A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer’s disease
Identifieur interne : 001C80 ( Pmc/Curation ); précédent : 001C79; suivant : 001C81A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer’s disease
Auteurs : Frank Jessen [Allemagne] ; Rebecca E. Amariglio [États-Unis] ; Martin Van Boxtel [Pays-Bas] ; Monique Breteler [Allemagne] ; Mathieu Ceccaldi [France] ; Gaël Chételat [France] ; Bruno Dubois [France] ; Carole Dufouil [France] ; Kathryn A. Ellis [Australie] ; Wiesje M. Van Der Flier [Pays-Bas] ; Lidia Glodzik [États-Unis] ; Argonde C. Van Harten [Pays-Bas] ; Mony J. De Leon [États-Unis] ; Pauline Mchugh [États-Unis] ; Michelle M. Mielke [États-Unis] ; Jose Luis Molinuevo [Espagne] ; Lisa Mosconi [États-Unis] ; Ricardo S. Osorio [États-Unis] ; Audrey Perrotin [France] ; Ronald C. Petersen [États-Unis] ; Laura A. Rabin [États-Unis] ; Lorena Rami [Espagne] ; Barry Reisberg [États-Unis] ; Dorene M. Rentz [États-Unis] ; Perminder S. Sachdev [Australie] ; Vincent De La Sayette [France] ; Andrew J. Saykin [États-Unis] ; Philip Scheltens [Pays-Bas] ; Melanie B. Shulman [États-Unis] ; Melissa J. Slavin [Australie] ; Reisa A. Sperling [États-Unis] ; Robert Stewart [Royaume-Uni] ; Olga Uspenskaya [France] ; Bruno Vellas [France] ; Pieter Jelle Visser [Pays-Bas] ; Michael Wagner [Allemagne]Source :
- Alzheimer's & dementia : the journal of the Alzheimer's Association [ 1552-5260 ] ; 2014.
Abstract
There is increasing evidence that subjective cognitive decline (SCD) in individuals with unimpaired performance on cognitive tests may represent the first symptomatic manifestation of Alzheimer’s disease (AD). The research on SCD in early AD, however, is limited by the absence of common standards. The working group of the Subjective Cognitive Decline Initiative (SCD-I) addressed this deficiency by reaching consensus on terminology and on a conceptual framework for research on SCD in AD. In this publication, research criteria for SCD in pre-mild cognitive impairment (MCI) are presented. In addition, a list of core features proposed for reporting in SCD studies is provided, which will enable comparability of research across different settings. Finally, a set of features is presented, which in accordance with current knowledge, increases the likelihood of the presence of preclinical AD in individuals with SCD. This list is referred to as SCD
Url:
DOI: 10.1016/j.jalz.2014.01.001
PubMed: 24798886
PubMed Central: 4317324
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: Pour aller vers cette notice dans l'étape Curation :001E24
Links to Exploration step
PMC:4317324Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer’s disease</title>
<author><name sortKey="Jessen, Frank" sort="Jessen, Frank" uniqKey="Jessen F" first="Frank" last="Jessen">Frank Jessen</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Department of Psychiatry, University of Bonn, Bonn, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Psychiatry, University of Bonn, Bonn</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A2">Clinical Treatment and Research Center for Neurodegenerative Disease (KBFZ), University of Bonn, Bonn, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Clinical Treatment and Research Center for Neurodegenerative Disease (KBFZ), University of Bonn, Bonn</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A3">German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Center for Neurodegenerative Diseases (DZNE), Bonn</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Amariglio, Rebecca E" sort="Amariglio, Rebecca E" uniqKey="Amariglio R" first="Rebecca E." last="Amariglio">Rebecca E. Amariglio</name>
<affiliation wicri:level="1"><nlm:aff id="A4">Department of Neurology, Harvard Medical School, Brigham and Women’s Hospital, Massachusetts General Hospital, Boston, MA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, Harvard Medical School, Brigham and Women’s Hospital, Massachusetts General Hospital, Boston, MA</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Boxtel, Martin" sort="Van Boxtel, Martin" uniqKey="Van Boxtel M" first="Martin" last="Van Boxtel">Martin Van Boxtel</name>
<affiliation wicri:level="1"><nlm:aff id="A5">Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience (MHeNS), Maastricht University, Maastricht, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience (MHeNS), Maastricht University, Maastricht</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Breteler, Monique" sort="Breteler, Monique" uniqKey="Breteler M" first="Monique" last="Breteler">Monique Breteler</name>
<affiliation wicri:level="1"><nlm:aff id="A3">German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Center for Neurodegenerative Diseases (DZNE), Bonn</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ceccaldi, Mathieu" sort="Ceccaldi, Mathieu" uniqKey="Ceccaldi M" first="Mathieu" last="Ceccaldi">Mathieu Ceccaldi</name>
<affiliation wicri:level="1"><nlm:aff id="A6">Institut des Neurosciences des Systèmes, Université de Marseille, Marseille, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institut des Neurosciences des Systèmes, Université de Marseille, Marseille</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Chetelat, Gael" sort="Chetelat, Gael" uniqKey="Chetelat G" first="Gaël" last="Chételat">Gaël Chételat</name>
<affiliation wicri:level="1"><nlm:aff id="A7">INSERM, U1077, Caen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM, U1077, Caen</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A8">Université de Caen Basse-Normandie, UMR-S1077, Caen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Université de Caen Basse-Normandie, UMR-S1077, Caen</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A9">Ecole Pratique des Hautes Etudes, UMR-S1077, Caen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Ecole Pratique des Hautes Etudes, UMR-S1077, Caen</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A10">CHU de Caen, U1077, Caen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>CHU de Caen, U1077, Caen</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Dubois, Bruno" sort="Dubois, Bruno" uniqKey="Dubois B" first="Bruno" last="Dubois">Bruno Dubois</name>
<affiliation wicri:level="1"><nlm:aff id="A11">Université Pierre et Marie Curie, Paris, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Université Pierre et Marie Curie, Paris</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Dufouil, Carole" sort="Dufouil, Carole" uniqKey="Dufouil C" first="Carole" last="Dufouil">Carole Dufouil</name>
<affiliation wicri:level="1"><nlm:aff id="A12">INSERM U708, Neuroepidemiology, CIC-EC7 and Bordeaux University, Bordeaux, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM U708, Neuroepidemiology, CIC-EC7 and Bordeaux University, Bordeaux</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ellis, Kathryn A" sort="Ellis, Kathryn A" uniqKey="Ellis K" first="Kathryn A." last="Ellis">Kathryn A. Ellis</name>
<affiliation wicri:level="1"><nlm:aff id="A13">Academic Unit for Psychiatry of Old Age, Department of Psychiatry, University of Melbourne, Melbourne, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Academic Unit for Psychiatry of Old Age, Department of Psychiatry, University of Melbourne, Melbourne</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Der Flier, Wiesje M" sort="Van Der Flier, Wiesje M" uniqKey="Van Der Flier W" first="Wiesje M." last="Van Der Flier">Wiesje M. Van Der Flier</name>
<affiliation wicri:level="1"><nlm:aff id="A14">Alzheimer Center, Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Centre, Amsterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Alzheimer Center, Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Centre, Amsterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Glodzik, Lidia" sort="Glodzik, Lidia" uniqKey="Glodzik L" first="Lidia" last="Glodzik">Lidia Glodzik</name>
<affiliation wicri:level="1"><nlm:aff id="A15">Department of Psychiatry, New York University Langone Medical Center, New York, NY, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry, New York University Langone Medical Center, New York, NY</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Harten, Argonde C" sort="Van Harten, Argonde C" uniqKey="Van Harten A" first="Argonde C." last="Van Harten">Argonde C. Van Harten</name>
<affiliation wicri:level="1"><nlm:aff id="A14">Alzheimer Center, Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Centre, Amsterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Alzheimer Center, Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Centre, Amsterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="De Leon, Mony J" sort="De Leon, Mony J" uniqKey="De Leon M" first="Mony J." last="De Leon">Mony J. De Leon</name>
<affiliation wicri:level="1"><nlm:aff id="A15">Department of Psychiatry, New York University Langone Medical Center, New York, NY, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry, New York University Langone Medical Center, New York, NY</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mchugh, Pauline" sort="Mchugh, Pauline" uniqKey="Mchugh P" first="Pauline" last="Mchugh">Pauline Mchugh</name>
<affiliation wicri:level="1"><nlm:aff id="A15">Department of Psychiatry, New York University Langone Medical Center, New York, NY, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry, New York University Langone Medical Center, New York, NY</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mielke, Michelle M" sort="Mielke, Michelle M" uniqKey="Mielke M" first="Michelle M." last="Mielke">Michelle M. Mielke</name>
<affiliation wicri:level="1"><nlm:aff id="A16">Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Health Sciences Research, Mayo Clinic, Rochester, MN</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Molinuevo, Jose Luis" sort="Molinuevo, Jose Luis" uniqKey="Molinuevo J" first="Jose Luis" last="Molinuevo">Jose Luis Molinuevo</name>
<affiliation wicri:level="1"><nlm:aff id="A17">Alzheimer’s Disease and Other Cognitive Disorders Unit, IDIBAPS, Hospital Clinic, Barcelona, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Alzheimer’s Disease and Other Cognitive Disorders Unit, IDIBAPS, Hospital Clinic, Barcelona</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mosconi, Lisa" sort="Mosconi, Lisa" uniqKey="Mosconi L" first="Lisa" last="Mosconi">Lisa Mosconi</name>
<affiliation wicri:level="1"><nlm:aff id="A15">Department of Psychiatry, New York University Langone Medical Center, New York, NY, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry, New York University Langone Medical Center, New York, NY</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Osorio, Ricardo S" sort="Osorio, Ricardo S" uniqKey="Osorio R" first="Ricardo S." last="Osorio">Ricardo S. Osorio</name>
<affiliation wicri:level="1"><nlm:aff id="A15">Department of Psychiatry, New York University Langone Medical Center, New York, NY, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry, New York University Langone Medical Center, New York, NY</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Perrotin, Audrey" sort="Perrotin, Audrey" uniqKey="Perrotin A" first="Audrey" last="Perrotin">Audrey Perrotin</name>
<affiliation wicri:level="1"><nlm:aff id="A7">INSERM, U1077, Caen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM, U1077, Caen</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A8">Université de Caen Basse-Normandie, UMR-S1077, Caen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Université de Caen Basse-Normandie, UMR-S1077, Caen</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A9">Ecole Pratique des Hautes Etudes, UMR-S1077, Caen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Ecole Pratique des Hautes Etudes, UMR-S1077, Caen</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A10">CHU de Caen, U1077, Caen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>CHU de Caen, U1077, Caen</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Petersen, Ronald C" sort="Petersen, Ronald C" uniqKey="Petersen R" first="Ronald C." last="Petersen">Ronald C. Petersen</name>
<affiliation wicri:level="1"><nlm:aff id="A18">Department of Neurology, Mayo Clinic, Rochester, MN, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, Mayo Clinic, Rochester, MN</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rabin, Laura A" sort="Rabin, Laura A" uniqKey="Rabin L" first="Laura A." last="Rabin">Laura A. Rabin</name>
<affiliation wicri:level="1"><nlm:aff id="A19">Brooklyn College of The City University of New York, New York, NY, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Brooklyn College of The City University of New York, New York, NY</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A20">The Graduate Center of The City University of New York, New York, NY, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>The Graduate Center of The City University of New York, New York, NY</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rami, Lorena" sort="Rami, Lorena" uniqKey="Rami L" first="Lorena" last="Rami">Lorena Rami</name>
<affiliation wicri:level="1"><nlm:aff id="A17">Alzheimer’s Disease and Other Cognitive Disorders Unit, IDIBAPS, Hospital Clinic, Barcelona, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Alzheimer’s Disease and Other Cognitive Disorders Unit, IDIBAPS, Hospital Clinic, Barcelona</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Reisberg, Barry" sort="Reisberg, Barry" uniqKey="Reisberg B" first="Barry" last="Reisberg">Barry Reisberg</name>
<affiliation wicri:level="1"><nlm:aff id="A15">Department of Psychiatry, New York University Langone Medical Center, New York, NY, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry, New York University Langone Medical Center, New York, NY</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A21">Silberstein Aging and Dementia Research Center, New York University School of Medicine, New York, NY, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Silberstein Aging and Dementia Research Center, New York University School of Medicine, New York, NY</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rentz, Dorene M" sort="Rentz, Dorene M" uniqKey="Rentz D" first="Dorene M." last="Rentz">Dorene M. Rentz</name>
<affiliation wicri:level="1"><nlm:aff id="A4">Department of Neurology, Harvard Medical School, Brigham and Women’s Hospital, Massachusetts General Hospital, Boston, MA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, Harvard Medical School, Brigham and Women’s Hospital, Massachusetts General Hospital, Boston, MA</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sachdev, Perminder S" sort="Sachdev, Perminder S" uniqKey="Sachdev P" first="Perminder S." last="Sachdev">Perminder S. Sachdev</name>
<affiliation wicri:level="1"><nlm:aff id="A22">Centre for Healthy Brain Ageing, University of New South Wales, Sydney, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Centre for Healthy Brain Ageing, University of New South Wales, Sydney</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="De La Sayette, Vincent" sort="De La Sayette, Vincent" uniqKey="De La Sayette V" first="Vincent" last="De La Sayette">Vincent De La Sayette</name>
<affiliation wicri:level="1"><nlm:aff id="A7">INSERM, U1077, Caen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM, U1077, Caen</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A8">Université de Caen Basse-Normandie, UMR-S1077, Caen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Université de Caen Basse-Normandie, UMR-S1077, Caen</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A9">Ecole Pratique des Hautes Etudes, UMR-S1077, Caen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Ecole Pratique des Hautes Etudes, UMR-S1077, Caen</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A10">CHU de Caen, U1077, Caen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>CHU de Caen, U1077, Caen</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Saykin, Andrew J" sort="Saykin, Andrew J" uniqKey="Saykin A" first="Andrew J." last="Saykin">Andrew J. Saykin</name>
<affiliation wicri:level="1"><nlm:aff id="A23">Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Scheltens, Philip" sort="Scheltens, Philip" uniqKey="Scheltens P" first="Philip" last="Scheltens">Philip Scheltens</name>
<affiliation wicri:level="1"><nlm:aff id="A14">Alzheimer Center, Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Centre, Amsterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Alzheimer Center, Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Centre, Amsterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Shulman, Melanie B" sort="Shulman, Melanie B" uniqKey="Shulman M" first="Melanie B." last="Shulman">Melanie B. Shulman</name>
<affiliation wicri:level="1"><nlm:aff id="A15">Department of Psychiatry, New York University Langone Medical Center, New York, NY, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry, New York University Langone Medical Center, New York, NY</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Slavin, Melissa J" sort="Slavin, Melissa J" uniqKey="Slavin M" first="Melissa J." last="Slavin">Melissa J. Slavin</name>
<affiliation wicri:level="1"><nlm:aff id="A24">Dementia Collaborative Research Centre, School of Psychiatry, UNSW Medicine, University of New South Wales, Sydney, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Dementia Collaborative Research Centre, School of Psychiatry, UNSW Medicine, University of New South Wales, Sydney</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sperling, Reisa A" sort="Sperling, Reisa A" uniqKey="Sperling R" first="Reisa A." last="Sperling">Reisa A. Sperling</name>
<affiliation wicri:level="1"><nlm:aff id="A4">Department of Neurology, Harvard Medical School, Brigham and Women’s Hospital, Massachusetts General Hospital, Boston, MA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, Harvard Medical School, Brigham and Women’s Hospital, Massachusetts General Hospital, Boston, MA</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Stewart, Robert" sort="Stewart, Robert" uniqKey="Stewart R" first="Robert" last="Stewart">Robert Stewart</name>
<affiliation wicri:level="1"><nlm:aff id="A25">Institute of Psychiatry, King’s College London, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Institute of Psychiatry, King’s College London, London</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Uspenskaya, Olga" sort="Uspenskaya, Olga" uniqKey="Uspenskaya O" first="Olga" last="Uspenskaya">Olga Uspenskaya</name>
<affiliation wicri:level="1"><nlm:aff id="A26">Alzheimer’s Institute, Groupe Hospitalier Pitié-Salpêtrière, Paris, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Alzheimer’s Institute, Groupe Hospitalier Pitié-Salpêtrière, Paris</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Vellas, Bruno" sort="Vellas, Bruno" uniqKey="Vellas B" first="Bruno" last="Vellas">Bruno Vellas</name>
<affiliation wicri:level="1"><nlm:aff id="A27">Department of Internal Medicine and Geriatrics, Toulouse University Hospital, UMR INSERM 1027, University Paul Sabatier, Toulouse, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Internal Medicine and Geriatrics, Toulouse University Hospital, UMR INSERM 1027, University Paul Sabatier, Toulouse</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Visser, Pieter Jelle" sort="Visser, Pieter Jelle" uniqKey="Visser P" first="Pieter Jelle" last="Visser">Pieter Jelle Visser</name>
<affiliation wicri:level="1"><nlm:aff id="A5">Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience (MHeNS), Maastricht University, Maastricht, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience (MHeNS), Maastricht University, Maastricht</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A14">Alzheimer Center, Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Centre, Amsterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Alzheimer Center, Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Centre, Amsterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wagner, Michael" sort="Wagner, Michael" uniqKey="Wagner M" first="Michael" last="Wagner">Michael Wagner</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Department of Psychiatry, University of Bonn, Bonn, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Psychiatry, University of Bonn, Bonn</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A2">Clinical Treatment and Research Center for Neurodegenerative Disease (KBFZ), University of Bonn, Bonn, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Clinical Treatment and Research Center for Neurodegenerative Disease (KBFZ), University of Bonn, Bonn</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A3">German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Center for Neurodegenerative Diseases (DZNE), Bonn</wicri:regionArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">24798886</idno>
<idno type="pmc">4317324</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317324</idno>
<idno type="RBID">PMC:4317324</idno>
<idno type="doi">10.1016/j.jalz.2014.01.001</idno>
<date when="2014">2014</date>
<idno type="wicri:Area/Pmc/Corpus">001E24</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001E24</idno>
<idno type="wicri:Area/Pmc/Curation">001C80</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001C80</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer’s disease</title>
<author><name sortKey="Jessen, Frank" sort="Jessen, Frank" uniqKey="Jessen F" first="Frank" last="Jessen">Frank Jessen</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Department of Psychiatry, University of Bonn, Bonn, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Psychiatry, University of Bonn, Bonn</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A2">Clinical Treatment and Research Center for Neurodegenerative Disease (KBFZ), University of Bonn, Bonn, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Clinical Treatment and Research Center for Neurodegenerative Disease (KBFZ), University of Bonn, Bonn</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A3">German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Center for Neurodegenerative Diseases (DZNE), Bonn</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Amariglio, Rebecca E" sort="Amariglio, Rebecca E" uniqKey="Amariglio R" first="Rebecca E." last="Amariglio">Rebecca E. Amariglio</name>
<affiliation wicri:level="1"><nlm:aff id="A4">Department of Neurology, Harvard Medical School, Brigham and Women’s Hospital, Massachusetts General Hospital, Boston, MA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, Harvard Medical School, Brigham and Women’s Hospital, Massachusetts General Hospital, Boston, MA</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Boxtel, Martin" sort="Van Boxtel, Martin" uniqKey="Van Boxtel M" first="Martin" last="Van Boxtel">Martin Van Boxtel</name>
<affiliation wicri:level="1"><nlm:aff id="A5">Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience (MHeNS), Maastricht University, Maastricht, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience (MHeNS), Maastricht University, Maastricht</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Breteler, Monique" sort="Breteler, Monique" uniqKey="Breteler M" first="Monique" last="Breteler">Monique Breteler</name>
<affiliation wicri:level="1"><nlm:aff id="A3">German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Center for Neurodegenerative Diseases (DZNE), Bonn</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ceccaldi, Mathieu" sort="Ceccaldi, Mathieu" uniqKey="Ceccaldi M" first="Mathieu" last="Ceccaldi">Mathieu Ceccaldi</name>
<affiliation wicri:level="1"><nlm:aff id="A6">Institut des Neurosciences des Systèmes, Université de Marseille, Marseille, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institut des Neurosciences des Systèmes, Université de Marseille, Marseille</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Chetelat, Gael" sort="Chetelat, Gael" uniqKey="Chetelat G" first="Gaël" last="Chételat">Gaël Chételat</name>
<affiliation wicri:level="1"><nlm:aff id="A7">INSERM, U1077, Caen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM, U1077, Caen</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A8">Université de Caen Basse-Normandie, UMR-S1077, Caen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Université de Caen Basse-Normandie, UMR-S1077, Caen</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A9">Ecole Pratique des Hautes Etudes, UMR-S1077, Caen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Ecole Pratique des Hautes Etudes, UMR-S1077, Caen</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A10">CHU de Caen, U1077, Caen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>CHU de Caen, U1077, Caen</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Dubois, Bruno" sort="Dubois, Bruno" uniqKey="Dubois B" first="Bruno" last="Dubois">Bruno Dubois</name>
<affiliation wicri:level="1"><nlm:aff id="A11">Université Pierre et Marie Curie, Paris, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Université Pierre et Marie Curie, Paris</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Dufouil, Carole" sort="Dufouil, Carole" uniqKey="Dufouil C" first="Carole" last="Dufouil">Carole Dufouil</name>
<affiliation wicri:level="1"><nlm:aff id="A12">INSERM U708, Neuroepidemiology, CIC-EC7 and Bordeaux University, Bordeaux, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM U708, Neuroepidemiology, CIC-EC7 and Bordeaux University, Bordeaux</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ellis, Kathryn A" sort="Ellis, Kathryn A" uniqKey="Ellis K" first="Kathryn A." last="Ellis">Kathryn A. Ellis</name>
<affiliation wicri:level="1"><nlm:aff id="A13">Academic Unit for Psychiatry of Old Age, Department of Psychiatry, University of Melbourne, Melbourne, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Academic Unit for Psychiatry of Old Age, Department of Psychiatry, University of Melbourne, Melbourne</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Der Flier, Wiesje M" sort="Van Der Flier, Wiesje M" uniqKey="Van Der Flier W" first="Wiesje M." last="Van Der Flier">Wiesje M. Van Der Flier</name>
<affiliation wicri:level="1"><nlm:aff id="A14">Alzheimer Center, Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Centre, Amsterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Alzheimer Center, Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Centre, Amsterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Glodzik, Lidia" sort="Glodzik, Lidia" uniqKey="Glodzik L" first="Lidia" last="Glodzik">Lidia Glodzik</name>
<affiliation wicri:level="1"><nlm:aff id="A15">Department of Psychiatry, New York University Langone Medical Center, New York, NY, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry, New York University Langone Medical Center, New York, NY</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Harten, Argonde C" sort="Van Harten, Argonde C" uniqKey="Van Harten A" first="Argonde C." last="Van Harten">Argonde C. Van Harten</name>
<affiliation wicri:level="1"><nlm:aff id="A14">Alzheimer Center, Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Centre, Amsterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Alzheimer Center, Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Centre, Amsterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="De Leon, Mony J" sort="De Leon, Mony J" uniqKey="De Leon M" first="Mony J." last="De Leon">Mony J. De Leon</name>
<affiliation wicri:level="1"><nlm:aff id="A15">Department of Psychiatry, New York University Langone Medical Center, New York, NY, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry, New York University Langone Medical Center, New York, NY</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mchugh, Pauline" sort="Mchugh, Pauline" uniqKey="Mchugh P" first="Pauline" last="Mchugh">Pauline Mchugh</name>
<affiliation wicri:level="1"><nlm:aff id="A15">Department of Psychiatry, New York University Langone Medical Center, New York, NY, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry, New York University Langone Medical Center, New York, NY</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mielke, Michelle M" sort="Mielke, Michelle M" uniqKey="Mielke M" first="Michelle M." last="Mielke">Michelle M. Mielke</name>
<affiliation wicri:level="1"><nlm:aff id="A16">Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Health Sciences Research, Mayo Clinic, Rochester, MN</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Molinuevo, Jose Luis" sort="Molinuevo, Jose Luis" uniqKey="Molinuevo J" first="Jose Luis" last="Molinuevo">Jose Luis Molinuevo</name>
<affiliation wicri:level="1"><nlm:aff id="A17">Alzheimer’s Disease and Other Cognitive Disorders Unit, IDIBAPS, Hospital Clinic, Barcelona, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Alzheimer’s Disease and Other Cognitive Disorders Unit, IDIBAPS, Hospital Clinic, Barcelona</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mosconi, Lisa" sort="Mosconi, Lisa" uniqKey="Mosconi L" first="Lisa" last="Mosconi">Lisa Mosconi</name>
<affiliation wicri:level="1"><nlm:aff id="A15">Department of Psychiatry, New York University Langone Medical Center, New York, NY, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry, New York University Langone Medical Center, New York, NY</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Osorio, Ricardo S" sort="Osorio, Ricardo S" uniqKey="Osorio R" first="Ricardo S." last="Osorio">Ricardo S. Osorio</name>
<affiliation wicri:level="1"><nlm:aff id="A15">Department of Psychiatry, New York University Langone Medical Center, New York, NY, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry, New York University Langone Medical Center, New York, NY</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Perrotin, Audrey" sort="Perrotin, Audrey" uniqKey="Perrotin A" first="Audrey" last="Perrotin">Audrey Perrotin</name>
<affiliation wicri:level="1"><nlm:aff id="A7">INSERM, U1077, Caen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM, U1077, Caen</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A8">Université de Caen Basse-Normandie, UMR-S1077, Caen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Université de Caen Basse-Normandie, UMR-S1077, Caen</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A9">Ecole Pratique des Hautes Etudes, UMR-S1077, Caen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Ecole Pratique des Hautes Etudes, UMR-S1077, Caen</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A10">CHU de Caen, U1077, Caen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>CHU de Caen, U1077, Caen</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Petersen, Ronald C" sort="Petersen, Ronald C" uniqKey="Petersen R" first="Ronald C." last="Petersen">Ronald C. Petersen</name>
<affiliation wicri:level="1"><nlm:aff id="A18">Department of Neurology, Mayo Clinic, Rochester, MN, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, Mayo Clinic, Rochester, MN</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rabin, Laura A" sort="Rabin, Laura A" uniqKey="Rabin L" first="Laura A." last="Rabin">Laura A. Rabin</name>
<affiliation wicri:level="1"><nlm:aff id="A19">Brooklyn College of The City University of New York, New York, NY, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Brooklyn College of The City University of New York, New York, NY</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A20">The Graduate Center of The City University of New York, New York, NY, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>The Graduate Center of The City University of New York, New York, NY</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rami, Lorena" sort="Rami, Lorena" uniqKey="Rami L" first="Lorena" last="Rami">Lorena Rami</name>
<affiliation wicri:level="1"><nlm:aff id="A17">Alzheimer’s Disease and Other Cognitive Disorders Unit, IDIBAPS, Hospital Clinic, Barcelona, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Alzheimer’s Disease and Other Cognitive Disorders Unit, IDIBAPS, Hospital Clinic, Barcelona</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Reisberg, Barry" sort="Reisberg, Barry" uniqKey="Reisberg B" first="Barry" last="Reisberg">Barry Reisberg</name>
<affiliation wicri:level="1"><nlm:aff id="A15">Department of Psychiatry, New York University Langone Medical Center, New York, NY, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry, New York University Langone Medical Center, New York, NY</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A21">Silberstein Aging and Dementia Research Center, New York University School of Medicine, New York, NY, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Silberstein Aging and Dementia Research Center, New York University School of Medicine, New York, NY</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rentz, Dorene M" sort="Rentz, Dorene M" uniqKey="Rentz D" first="Dorene M." last="Rentz">Dorene M. Rentz</name>
<affiliation wicri:level="1"><nlm:aff id="A4">Department of Neurology, Harvard Medical School, Brigham and Women’s Hospital, Massachusetts General Hospital, Boston, MA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, Harvard Medical School, Brigham and Women’s Hospital, Massachusetts General Hospital, Boston, MA</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sachdev, Perminder S" sort="Sachdev, Perminder S" uniqKey="Sachdev P" first="Perminder S." last="Sachdev">Perminder S. Sachdev</name>
<affiliation wicri:level="1"><nlm:aff id="A22">Centre for Healthy Brain Ageing, University of New South Wales, Sydney, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Centre for Healthy Brain Ageing, University of New South Wales, Sydney</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="De La Sayette, Vincent" sort="De La Sayette, Vincent" uniqKey="De La Sayette V" first="Vincent" last="De La Sayette">Vincent De La Sayette</name>
<affiliation wicri:level="1"><nlm:aff id="A7">INSERM, U1077, Caen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM, U1077, Caen</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A8">Université de Caen Basse-Normandie, UMR-S1077, Caen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Université de Caen Basse-Normandie, UMR-S1077, Caen</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A9">Ecole Pratique des Hautes Etudes, UMR-S1077, Caen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Ecole Pratique des Hautes Etudes, UMR-S1077, Caen</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A10">CHU de Caen, U1077, Caen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>CHU de Caen, U1077, Caen</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Saykin, Andrew J" sort="Saykin, Andrew J" uniqKey="Saykin A" first="Andrew J." last="Saykin">Andrew J. Saykin</name>
<affiliation wicri:level="1"><nlm:aff id="A23">Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Scheltens, Philip" sort="Scheltens, Philip" uniqKey="Scheltens P" first="Philip" last="Scheltens">Philip Scheltens</name>
<affiliation wicri:level="1"><nlm:aff id="A14">Alzheimer Center, Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Centre, Amsterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Alzheimer Center, Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Centre, Amsterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Shulman, Melanie B" sort="Shulman, Melanie B" uniqKey="Shulman M" first="Melanie B." last="Shulman">Melanie B. Shulman</name>
<affiliation wicri:level="1"><nlm:aff id="A15">Department of Psychiatry, New York University Langone Medical Center, New York, NY, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry, New York University Langone Medical Center, New York, NY</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Slavin, Melissa J" sort="Slavin, Melissa J" uniqKey="Slavin M" first="Melissa J." last="Slavin">Melissa J. Slavin</name>
<affiliation wicri:level="1"><nlm:aff id="A24">Dementia Collaborative Research Centre, School of Psychiatry, UNSW Medicine, University of New South Wales, Sydney, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Dementia Collaborative Research Centre, School of Psychiatry, UNSW Medicine, University of New South Wales, Sydney</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sperling, Reisa A" sort="Sperling, Reisa A" uniqKey="Sperling R" first="Reisa A." last="Sperling">Reisa A. Sperling</name>
<affiliation wicri:level="1"><nlm:aff id="A4">Department of Neurology, Harvard Medical School, Brigham and Women’s Hospital, Massachusetts General Hospital, Boston, MA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, Harvard Medical School, Brigham and Women’s Hospital, Massachusetts General Hospital, Boston, MA</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Stewart, Robert" sort="Stewart, Robert" uniqKey="Stewart R" first="Robert" last="Stewart">Robert Stewart</name>
<affiliation wicri:level="1"><nlm:aff id="A25">Institute of Psychiatry, King’s College London, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Institute of Psychiatry, King’s College London, London</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Uspenskaya, Olga" sort="Uspenskaya, Olga" uniqKey="Uspenskaya O" first="Olga" last="Uspenskaya">Olga Uspenskaya</name>
<affiliation wicri:level="1"><nlm:aff id="A26">Alzheimer’s Institute, Groupe Hospitalier Pitié-Salpêtrière, Paris, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Alzheimer’s Institute, Groupe Hospitalier Pitié-Salpêtrière, Paris</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Vellas, Bruno" sort="Vellas, Bruno" uniqKey="Vellas B" first="Bruno" last="Vellas">Bruno Vellas</name>
<affiliation wicri:level="1"><nlm:aff id="A27">Department of Internal Medicine and Geriatrics, Toulouse University Hospital, UMR INSERM 1027, University Paul Sabatier, Toulouse, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Internal Medicine and Geriatrics, Toulouse University Hospital, UMR INSERM 1027, University Paul Sabatier, Toulouse</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Visser, Pieter Jelle" sort="Visser, Pieter Jelle" uniqKey="Visser P" first="Pieter Jelle" last="Visser">Pieter Jelle Visser</name>
<affiliation wicri:level="1"><nlm:aff id="A5">Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience (MHeNS), Maastricht University, Maastricht, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience (MHeNS), Maastricht University, Maastricht</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A14">Alzheimer Center, Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Centre, Amsterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Alzheimer Center, Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Centre, Amsterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wagner, Michael" sort="Wagner, Michael" uniqKey="Wagner M" first="Michael" last="Wagner">Michael Wagner</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Department of Psychiatry, University of Bonn, Bonn, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Psychiatry, University of Bonn, Bonn</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A2">Clinical Treatment and Research Center for Neurodegenerative Disease (KBFZ), University of Bonn, Bonn, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Clinical Treatment and Research Center for Neurodegenerative Disease (KBFZ), University of Bonn, Bonn</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A3">German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Center for Neurodegenerative Diseases (DZNE), Bonn</wicri:regionArea>
</affiliation>
</author>
</analytic>
<series><title level="j">Alzheimer's & dementia : the journal of the Alzheimer's Association</title>
<idno type="ISSN">1552-5260</idno>
<idno type="eISSN">1552-5279</idno>
<imprint><date when="2014">2014</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p id="P1">There is increasing evidence that subjective cognitive decline (SCD) in individuals with unimpaired performance on cognitive tests may represent the first symptomatic manifestation of Alzheimer’s disease (AD). The research on SCD in early AD, however, is limited by the absence of common standards. The working group of the Subjective Cognitive Decline Initiative (SCD-I) addressed this deficiency by reaching consensus on terminology and on a conceptual framework for research on SCD in AD. In this publication, research criteria for SCD in pre-mild cognitive impairment (MCI) are presented. In addition, a list of core features proposed for reporting in SCD studies is provided, which will enable comparability of research across different settings. Finally, a set of features is presented, which in accordance with current knowledge, increases the likelihood of the presence of preclinical AD in individuals with SCD. This list is referred to as SCD <italic>plus</italic>
.</p>
</div>
</front>
</TEI>
<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">101231978</journal-id>
<journal-id journal-id-type="pubmed-jr-id">33173</journal-id>
<journal-id journal-id-type="nlm-ta">Alzheimers Dement</journal-id>
<journal-id journal-id-type="iso-abbrev">Alzheimers Dement</journal-id>
<journal-title-group><journal-title>Alzheimer's & dementia : the journal of the Alzheimer's Association</journal-title>
</journal-title-group>
<issn pub-type="ppub">1552-5260</issn>
<issn pub-type="epub">1552-5279</issn>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">24798886</article-id>
<article-id pub-id-type="pmc">4317324</article-id>
<article-id pub-id-type="doi">10.1016/j.jalz.2014.01.001</article-id>
<article-id pub-id-type="manuscript">NIHMS643057</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer’s disease</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Jessen</surname>
<given-names>Frank</given-names>
</name>
<xref ref-type="aff" rid="A1">a</xref>
<xref ref-type="aff" rid="A2">b</xref>
<xref ref-type="aff" rid="A3">c</xref>
<xref rid="FN1" ref-type="author-notes">*</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Amariglio</surname>
<given-names>Rebecca E.</given-names>
</name>
<xref ref-type="aff" rid="A4">d</xref>
</contrib>
<contrib contrib-type="author"><name><surname>van Boxtel</surname>
<given-names>Martin</given-names>
</name>
<xref ref-type="aff" rid="A5">e</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Breteler</surname>
<given-names>Monique</given-names>
</name>
<xref ref-type="aff" rid="A3">c</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Ceccaldi</surname>
<given-names>Mathieu</given-names>
</name>
<xref ref-type="aff" rid="A6">f</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Chételat</surname>
<given-names>Gaël</given-names>
</name>
<xref ref-type="aff" rid="A7">g</xref>
<xref ref-type="aff" rid="A8">h</xref>
<xref ref-type="aff" rid="A9">i</xref>
<xref ref-type="aff" rid="A10">j</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Dubois</surname>
<given-names>Bruno</given-names>
</name>
<xref ref-type="aff" rid="A11">k</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Dufouil</surname>
<given-names>Carole</given-names>
</name>
<xref ref-type="aff" rid="A12">l</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Ellis</surname>
<given-names>Kathryn A.</given-names>
</name>
<xref ref-type="aff" rid="A13">m</xref>
</contrib>
<contrib contrib-type="author"><name><surname>van der Flier</surname>
<given-names>Wiesje M.</given-names>
</name>
<xref ref-type="aff" rid="A14">n</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Glodzik</surname>
<given-names>Lidia</given-names>
</name>
<xref ref-type="aff" rid="A15">o</xref>
</contrib>
<contrib contrib-type="author"><name><surname>van Harten</surname>
<given-names>Argonde C.</given-names>
</name>
<xref ref-type="aff" rid="A14">n</xref>
</contrib>
<contrib contrib-type="author"><name><surname>de Leon</surname>
<given-names>Mony J.</given-names>
</name>
<xref ref-type="aff" rid="A15">o</xref>
</contrib>
<contrib contrib-type="author"><name><surname>McHugh</surname>
<given-names>Pauline</given-names>
</name>
<xref ref-type="aff" rid="A15">o</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Mielke</surname>
<given-names>Michelle M.</given-names>
</name>
<xref ref-type="aff" rid="A16">p</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Molinuevo</surname>
<given-names>Jose Luis</given-names>
</name>
<xref ref-type="aff" rid="A17">q</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Mosconi</surname>
<given-names>Lisa</given-names>
</name>
<xref ref-type="aff" rid="A15">o</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Osorio</surname>
<given-names>Ricardo S.</given-names>
</name>
<xref ref-type="aff" rid="A15">o</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Perrotin</surname>
<given-names>Audrey</given-names>
</name>
<xref ref-type="aff" rid="A7">g</xref>
<xref ref-type="aff" rid="A8">h</xref>
<xref ref-type="aff" rid="A9">i</xref>
<xref ref-type="aff" rid="A10">j</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Petersen</surname>
<given-names>Ronald C.</given-names>
</name>
<xref ref-type="aff" rid="A18">r</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Rabin</surname>
<given-names>Laura A.</given-names>
</name>
<xref ref-type="aff" rid="A19">s</xref>
<xref ref-type="aff" rid="A20">t</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Rami</surname>
<given-names>Lorena</given-names>
</name>
<xref ref-type="aff" rid="A17">q</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Reisberg</surname>
<given-names>Barry</given-names>
</name>
<xref ref-type="aff" rid="A15">o</xref>
<xref ref-type="aff" rid="A21">u</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Rentz</surname>
<given-names>Dorene M.</given-names>
</name>
<xref ref-type="aff" rid="A4">d</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Sachdev</surname>
<given-names>Perminder S.</given-names>
</name>
<xref ref-type="aff" rid="A22">v</xref>
</contrib>
<contrib contrib-type="author"><name><surname>de la Sayette</surname>
<given-names>Vincent</given-names>
</name>
<xref ref-type="aff" rid="A7">g</xref>
<xref ref-type="aff" rid="A8">h</xref>
<xref ref-type="aff" rid="A9">i</xref>
<xref ref-type="aff" rid="A10">j</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Saykin</surname>
<given-names>Andrew J.</given-names>
</name>
<xref ref-type="aff" rid="A23">w</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Scheltens</surname>
<given-names>Philip</given-names>
</name>
<xref ref-type="aff" rid="A14">n</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Shulman</surname>
<given-names>Melanie B.</given-names>
</name>
<xref ref-type="aff" rid="A15">o</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Slavin</surname>
<given-names>Melissa J.</given-names>
</name>
<xref ref-type="aff" rid="A24">x</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Sperling</surname>
<given-names>Reisa A.</given-names>
</name>
<xref ref-type="aff" rid="A4">d</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Stewart</surname>
<given-names>Robert</given-names>
</name>
<xref ref-type="aff" rid="A25">y</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Uspenskaya</surname>
<given-names>Olga</given-names>
</name>
<xref ref-type="aff" rid="A26">z</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Vellas</surname>
<given-names>Bruno</given-names>
</name>
<xref ref-type="aff" rid="A27">aa</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Visser</surname>
<given-names>Pieter Jelle</given-names>
</name>
<xref ref-type="aff" rid="A5">e</xref>
<xref ref-type="aff" rid="A14">n</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Wagner</surname>
<given-names>Michael</given-names>
</name>
<xref ref-type="aff" rid="A1">a</xref>
<xref ref-type="aff" rid="A2">b</xref>
<xref ref-type="aff" rid="A3">c</xref>
</contrib>
<contrib contrib-type="author"><collab>Subjective Cognitive Decline Initiative (SCD-I) Working Group</collab>
</contrib>
</contrib-group>
<aff id="A1"><label>a</label>
Department of Psychiatry, University of Bonn, Bonn, Germany</aff>
<aff id="A2"><label>b</label>
Clinical Treatment and Research Center for Neurodegenerative Disease (KBFZ), University of Bonn, Bonn, Germany</aff>
<aff id="A3"><label>c</label>
German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany</aff>
<aff id="A4"><label>d</label>
Department of Neurology, Harvard Medical School, Brigham and Women’s Hospital, Massachusetts General Hospital, Boston, MA, USA</aff>
<aff id="A5"><label>e</label>
Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience (MHeNS), Maastricht University, Maastricht, The Netherlands</aff>
<aff id="A6"><label>f</label>
Institut des Neurosciences des Systèmes, Université de Marseille, Marseille, France</aff>
<aff id="A7"><label>g</label>
INSERM, U1077, Caen, France</aff>
<aff id="A8"><label>h</label>
Université de Caen Basse-Normandie, UMR-S1077, Caen, France</aff>
<aff id="A9"><label>i</label>
Ecole Pratique des Hautes Etudes, UMR-S1077, Caen, France</aff>
<aff id="A10"><label>j</label>
CHU de Caen, U1077, Caen, France</aff>
<aff id="A11"><label>k</label>
Université Pierre et Marie Curie, Paris, France</aff>
<aff id="A12"><label>l</label>
INSERM U708, Neuroepidemiology, CIC-EC7 and Bordeaux University, Bordeaux, France</aff>
<aff id="A13"><label>m</label>
Academic Unit for Psychiatry of Old Age, Department of Psychiatry, University of Melbourne, Melbourne, Australia</aff>
<aff id="A14"><label>n</label>
Alzheimer Center, Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Centre, Amsterdam, The Netherlands</aff>
<aff id="A15"><label>o</label>
Department of Psychiatry, New York University Langone Medical Center, New York, NY, USA</aff>
<aff id="A16"><label>p</label>
Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA</aff>
<aff id="A17"><label>q</label>
Alzheimer’s Disease and Other Cognitive Disorders Unit, IDIBAPS, Hospital Clinic, Barcelona, Spain</aff>
<aff id="A18"><label>r</label>
Department of Neurology, Mayo Clinic, Rochester, MN, USA</aff>
<aff id="A19"><label>s</label>
Brooklyn College of The City University of New York, New York, NY, USA</aff>
<aff id="A20"><label>t</label>
The Graduate Center of The City University of New York, New York, NY, USA</aff>
<aff id="A21"><label>u</label>
Silberstein Aging and Dementia Research Center, New York University School of Medicine, New York, NY, USA</aff>
<aff id="A22"><label>v</label>
Centre for Healthy Brain Ageing, University of New South Wales, Sydney, Australia</aff>
<aff id="A23"><label>w</label>
Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA</aff>
<aff id="A24"><label>x</label>
Dementia Collaborative Research Centre, School of Psychiatry, UNSW Medicine, University of New South Wales, Sydney, Australia</aff>
<aff id="A25"><label>y</label>
Institute of Psychiatry, King’s College London, London, UK</aff>
<aff id="A26"><label>z</label>
Alzheimer’s Institute, Groupe Hospitalier Pitié-Salpêtrière, Paris, France</aff>
<aff id="A27"><label>aa</label>
Department of Internal Medicine and Geriatrics, Toulouse University Hospital, UMR INSERM 1027, University Paul Sabatier, Toulouse, France</aff>
<author-notes><corresp id="FN1"><label>*</label>
Corresponding author. Tel.: +49-228-287-11109; Fax: +49-228-287-19732., <email>frank.jessen@ukb.uni-bonn.de</email>
</corresp>
</author-notes>
<pub-date pub-type="nihms-submitted"><day>18</day>
<month>11</month>
<year>2014</year>
</pub-date>
<pub-date pub-type="epub"><day>03</day>
<month>5</month>
<year>2014</year>
</pub-date>
<pub-date pub-type="ppub"><month>11</month>
<year>2014</year>
</pub-date>
<pub-date pub-type="pmc-release"><day>01</day>
<month>11</month>
<year>2015</year>
</pub-date>
<volume>10</volume>
<issue>6</issue>
<fpage>844</fpage>
<lpage>852</lpage>
<pmc-comment>elocation-id from pubmed: 10.1016/j.jalz.2014.01.001</pmc-comment>
<permissions><copyright-statement>© 2014 The Alzheimer’s Association. All rights reserved.</copyright-statement>
<copyright-year>2014</copyright-year>
</permissions>
<abstract><p id="P1">There is increasing evidence that subjective cognitive decline (SCD) in individuals with unimpaired performance on cognitive tests may represent the first symptomatic manifestation of Alzheimer’s disease (AD). The research on SCD in early AD, however, is limited by the absence of common standards. The working group of the Subjective Cognitive Decline Initiative (SCD-I) addressed this deficiency by reaching consensus on terminology and on a conceptual framework for research on SCD in AD. In this publication, research criteria for SCD in pre-mild cognitive impairment (MCI) are presented. In addition, a list of core features proposed for reporting in SCD studies is provided, which will enable comparability of research across different settings. Finally, a set of features is presented, which in accordance with current knowledge, increases the likelihood of the presence of preclinical AD in individuals with SCD. This list is referred to as SCD <italic>plus</italic>
.</p>
</abstract>
<kwd-group><kwd>Alzheimer’s disease</kwd>
<kwd>Subjective cognitive decline</kwd>
<kwd>Preclinical Alzheimer’s disease</kwd>
<kwd>Mild cognitive impairment</kwd>
<kwd>Prodromal Alzheimer ’s disease</kwd>
<kwd>Research criteria</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Pmc/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001C80 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Curation/biblio.hfd -nk 001C80 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Asie |area= AustralieFrV1 |flux= Pmc |étape= Curation |type= RBID |clé= PMC:4317324 |texte= A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer’s disease }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Curation/RBID.i -Sk "pubmed:24798886" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Curation/biblio.hfd \ | NlmPubMed2Wicri -a AustralieFrV1
![]() | This area was generated with Dilib version V0.6.33. | ![]() |