Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers
Identifieur interne : 001724 ( Pmc/Curation ); précédent : 001723; suivant : 001725Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers
Auteurs : Antonis C. Antoniou ; Christiana Kartsonaki ; Olga M. Sinilnikova [France] ; Penny Soucy ; Lesley Mcguffog ; Sue Healey [Australie] ; Andrew Lee ; Paolo Peterlongo [Italie] ; Siranoush Manoukian [Italie] ; Bernard Peissel [Italie] ; Daniela Zaffaroni [Italie] ; Elisa Cattaneo [Italie] ; Monica Barile [Italie] ; Valeria Pensotti [Italie] ; Barbara Pasini [Italie] ; Riccardo Dolcetti [Italie] ; Giuseppe Giannini [Italie] ; Anna Laura Putignano [Italie] ; Liliana Varesco [Italie] ; Paolo Radice ; Phuong L. Mai [États-Unis] ; Mark H. Greene [États-Unis] ; Irene L. Andrulis [Canada] ; Gord Glendon [Canada] ; Hilmi Ozcelik [Canada] ; Mads Thomassen [Danemark] ; Anne-Marie Gerdes [Danemark] ; Torben A. Kruse [Danemark] ; Uffe Birk Jensen [Danemark] ; Dorthe G. Crüger [Danemark] ; Maria A. Caligo [Italie] ; Yael Laitman [Israël] ; Roni Milgrom [Israël] ; Bella Kaufman [Israël] ; Shani Paluch-Shimon [Israël] ; Eitan Friedman [Israël] ; Niklas Loman [Suède] ; Katja Harbst [Suède] ; Annika Lindblom ; Brita Arver [Suède] ; Hans Ehrencrona [Suède] ; Beatrice Melin [Suède] ; Katherine L. Nathanson [États-Unis] ; Susan M. Domchek [États-Unis] ; Timothy Rebbeck [États-Unis] ; Ania Jakubowska [Pologne] ; Jan Lubinski [Pologne] ; Jacek Gronwald [Pologne] ; Tomasz Huzarski [Pologne] ; Tomasz Byrski [Pologne] ; Cezary Cybulski [Pologne] ; Bohdan Gorski [Pologne] ; Ana Osorio [Espagne] ; Teresa Ram N Y Cajal [Espagne] ; Florentia Fostira [Grèce] ; Raquel Andrés [Espagne] ; Javier Benitez [Espagne] ; Ute Hamann [Allemagne] ; Frans B. Hogervorst ; Matti A. Rookus [Pays-Bas] ; Maartje J. Hooning [Pays-Bas] ; Marcel R. Nelen [Pays-Bas] ; Rob B. Van Der Luijt [Pays-Bas] ; Theo A. M. Van Os [Pays-Bas] ; Christi J. Van Asperen ; Peter Devilee [Pays-Bas] ; Hanne E. J. Meijers-Heijboer [Pays-Bas] ; Encarna B. G Mez Garcia [Pays-Bas] ; Susan Peock ; Margaret Cook ; Debra Frost ; Radka Platte ; Jean Leyland ; D. Gareth Evans [Royaume-Uni] ; Fiona Lalloo [Royaume-Uni] ; Ros Eeles [Royaume-Uni] ; Louise Izatt [Royaume-Uni] ; Julian Adlard [Royaume-Uni] ; Rosemarie Davidson [Royaume-Uni] ; Diana Eccles [Royaume-Uni] ; Kai-Ren Ong [Royaume-Uni] ; Jackie Cook [Royaume-Uni] ; Fiona Douglas [Royaume-Uni] ; Joan Paterson [Royaume-Uni] ; M. John Kennedy ; Zosia Miedzybrodzka [Royaume-Uni] ; Andrew Godwin [États-Unis] ; Dominique Stoppa-Lyonnet [France] ; Bruno Buecher ; Muriel Belotti ; Carole Tirapo ; Sylvie Mazoyer [France] ; Laure Barjhoux [France] ; Christine Lasset [France] ; Dominique Leroux [France] ; Laurence Faivre [France] ; Myriam Bronner [France] ; Fabienne Prieur [France] ; Catherine Nogues ; Etienne Rouleau [France] ; Pascal Pujol [France] ; Isabelle Coupier [France] ; Marc Frénay [France] ; John L. Hopper [Australie] ; Mary B. Daly [États-Unis] ; Mary B. Terry [États-Unis] ; Esther M. John [États-Unis] ; Saundra S. Buys [États-Unis] ; Yosuf Yassin [États-Unis] ; Alexander Miron [États-Unis] ; David Goldgar [États-Unis] ; Christian F. Singer [Autriche] ; Muy-Kheng Tea [Autriche] ; Georg Pfeiler [Autriche] ; Anne Catharina Dressler [Autriche] ; Thomas V. O. Hansen ; Lars J Nson ; Bent Ejlertsen [Danemark] ; Rosa Bjork Barkardottir [Islande] ; Tomas Kirchhoff [États-Unis] ; Kenneth Offit [États-Unis] ; Marion Piedmonte ; Gustavo Rodriguez [États-Unis] ; Laurie Small [États-Unis] ; John Boggess [États-Unis] ; Stephanie Blank [États-Unis] ; Jack Basil [États-Unis] ; Masoud Azodi [États-Unis] ; Amanda Ewart Toland [États-Unis] ; Marco Montagna [Italie] ; Silvia Tognazzo [Italie] ; Simona Agata [Italie] ; Evgeny Imyanitov [Russie] ; Ramunas Janavicius [Lituanie] ; Conxi Lazaro [Espagne] ; Ignacio Blanco [Espagne] ; Paul D. P. Pharoah [Royaume-Uni] ; Lara Sucheston [États-Unis] ; Beth Y. Karlan [États-Unis] ; Christine S. Walsh [États-Unis] ; Edith Olah [Hongrie] ; Aniko Bozsik [Hongrie] ; Soo-Hwang Teo [Malaisie] ; Joyce L. Seldon [États-Unis] ; Mary S. Beattie [États-Unis] ; Elizabeth J. Van Rensburg [Afrique du Sud] ; Michelle D. Sluiter [Afrique du Sud] ; Orland Diez [Espagne] ; Rita K. Schmutzler [Allemagne] ; Barbara Wappenschmidt [Allemagne] ; Christoph Engel [Allemagne] ; Alfons Meindl [Allemagne] ; Ina Ruehl [Allemagne] ; Raymonda Varon-Mateeva [Allemagne] ; Karin Kast [Allemagne] ; Helmut Deissler [Allemagne] ; Dieter Niederacher [Allemagne] ; Norbert Arnold [Allemagne] ; Dorothea Gadzicki [Allemagne] ; Ines Schönbuchner [Allemagne] ; Trinidad Caldes [Espagne] ; Miguel De La Hoya [Espagne] ; Heli Nevanlinna ; Kristiina Aittom Ki [Finlande] ; Martine Dumont ; Jocelyne Chiquette [Canada] ; Marc Tischkowitz [Canada] ; Xiaoqing Chen [Australie] ; Jonathan Beesley [Australie] ; Amanda B. Spurdle [Australie] ; Susan L. Neuhausen [États-Unis] ; Yuan Chun Ding [États-Unis] ; Zachary Fredericksen [États-Unis] ; Xianshu Wang [États-Unis] ; Vernon S. Pankratz [États-Unis] ; Fergus Couch [États-Unis] ; Jacques Simard [Canada] ; Douglas F. Easton ; Georgia Chenevix-Trench [Australie]Source :
- Human Molecular Genetics [ 0964-6906 ] ; 2011.
Abstract
Two single nucleotide polymorphisms (SNPs) at 6q25.1, near the
Url:
DOI: 10.1093/hmg/ddr226
PubMed: 21593217
PubMed Central: 3652640
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PMC:3652640Curation
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Paolo Peterlongo<affiliation><nlm:aff wicri:cut=" and" id="af9"><addr-line>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine</addr-line>
</nlm:aff>
<wicri:noCountry code="subfield">Department of Preventive and Predictive Medicine</wicri:noCountry>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af11"><addr-line>IFOM</addr-line>
,<institution>Fondazione Istituto FIRC di Oncologia Molecolare</institution>
,<addr-line>Milan</addr-line>
,<country>Italy</country>
,</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation><nlm:aff wicri:cut=" and" id="af9"><addr-line>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine</addr-line>
</nlm:aff>
<wicri:noCountry code="subfield">Department of Preventive and Predictive Medicine</wicri:noCountry>
</affiliation>
<affiliation><nlm:aff wicri:cut=" and" id="af58"><addr-line>Department of Clinical Genetics and GROM, School for Oncology</addr-line>
</nlm:aff>
<wicri:noCountry code="subfield">School for Oncology</wicri:noCountry>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af59"><addr-line>Developmental Biology</addr-line>
,<institution>MUMC</institution>
,<addr-line>Maastricht</addr-line>
,<country>The Netherlands</country>
,</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation><nlm:aff id="af70"><addr-line>Academic Unit of Clinical and Molecular Oncology</addr-line>
,<institution>Trinity College Dublin and St James's Hospital</institution>
,<addr-line>Dublin</addr-line>
,<country>Eire</country>
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<wicri:noCountry code="nlm country">Eire</wicri:noCountry>
</affiliation>
<affiliation><nlm:aff wicri:cut=" and" id="af99"><addr-line>Genomic Medicine, Department of Clinical Biochemistry</addr-line>
</nlm:aff>
<wicri:noCountry code="subfield">Department of Clinical Biochemistry</wicri:noCountry>
</affiliation>
<affiliation><nlm:aff wicri:cut=" and" id="af99"><addr-line>Genomic Medicine, Department of Clinical Biochemistry</addr-line>
</nlm:aff>
<wicri:noCountry code="subfield">Department of Clinical Biochemistry</wicri:noCountry>
</affiliation>
<affiliation><nlm:aff wicri:cut=" and" id="af130"><addr-line>Centre of Familial Breast and Ovarian Cancer, Department of Gynaecology and Obstetrics</addr-line>
</nlm:aff>
<wicri:noCountry code="subfield">Department of Gynaecology and Obstetrics</wicri:noCountry>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af131"><addr-line>Centre for Integrated Oncology (CIO)</addr-line>
,<institution>University hospital of Cologne</institution>
,<addr-line>Cologne</addr-line>
,<country>Germany</country>
,</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation><nlm:aff wicri:cut=" and" id="af130"><addr-line>Centre of Familial Breast and Ovarian Cancer, Department of Gynaecology and Obstetrics</addr-line>
</nlm:aff>
<wicri:noCountry code="subfield">Department of Gynaecology and Obstetrics</wicri:noCountry>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af131"><addr-line>Centre for Integrated Oncology (CIO)</addr-line>
,<institution>University hospital of Cologne</institution>
,<addr-line>Cologne</addr-line>
,<country>Germany</country>
,</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
Le document en format XML
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mutation carriers</title>
<author><name sortKey="Antoniou, Antonis C" sort="Antoniou, Antonis C" uniqKey="Antoniou A" first="Antonis C" last="Antoniou">Antonis C. Antoniou</name>
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<author><name sortKey="Sinilnikova, Olga M" sort="Sinilnikova, Olga M" uniqKey="Sinilnikova O" first="Olga M." last="Sinilnikova">Olga M. Sinilnikova</name>
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<affiliation wicri:level="1"><nlm:aff id="af4"><addr-line>Equipe labellisée LIGUE 2008, UMR5201 CNRS, Centre Léon Bérard</addr-line>
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<country xml:lang="fr">France</country>
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<author><name sortKey="Soucy, Penny" sort="Soucy, Penny" uniqKey="Soucy P" first="Penny" last="Soucy">Penny Soucy</name>
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<author><name sortKey="Mcguffog, Lesley" sort="Mcguffog, Lesley" uniqKey="Mcguffog L" first="Lesley" last="Mcguffog">Lesley Mcguffog</name>
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<author><name sortKey="Healey, Sue" sort="Healey, Sue" uniqKey="Healey S" first="Sue" last="Healey">Sue Healey</name>
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<country xml:lang="fr">Australie</country>
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<author><name sortKey="Lee, Andrew" sort="Lee, Andrew" uniqKey="Lee A" first="Andrew" last="Lee">Andrew Lee</name>
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<author><name sortKey="Peterlongo, Paolo" sort="Peterlongo, Paolo" uniqKey="Peterlongo P" first="Paolo" last="Peterlongo">Paolo Peterlongo</name>
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<country xml:lang="fr">Italie</country>
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<author><name sortKey="Manoukian, Siranoush" sort="Manoukian, Siranoush" uniqKey="Manoukian S" first="Siranoush" last="Manoukian">Siranoush Manoukian</name>
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<author><name sortKey="Peissel, Bernard" sort="Peissel, Bernard" uniqKey="Peissel B" first="Bernard" last="Peissel">Bernard Peissel</name>
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<country xml:lang="fr">Italie</country>
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<author><name sortKey="Zaffaroni, Daniela" sort="Zaffaroni, Daniela" uniqKey="Zaffaroni D" first="Daniela" last="Zaffaroni">Daniela Zaffaroni</name>
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,<country>Italy</country>
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<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="Cattaneo, Elisa" sort="Cattaneo, Elisa" uniqKey="Cattaneo E" first="Elisa" last="Cattaneo">Elisa Cattaneo</name>
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<country xml:lang="fr">Italie</country>
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<author><name sortKey="Barile, Monica" sort="Barile, Monica" uniqKey="Barile M" first="Monica" last="Barile">Monica Barile</name>
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<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="Pensotti, Valeria" sort="Pensotti, Valeria" uniqKey="Pensotti V" first="Valeria" last="Pensotti">Valeria Pensotti</name>
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,<institution>Consortium for Genomics Technology</institution>
,<addr-line>Milan</addr-line>
,<country>Italy</country>
,</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="Pasini, Barbara" sort="Pasini, Barbara" uniqKey="Pasini B" first="Barbara" last="Pasini">Barbara Pasini</name>
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,<institution>University of Turin</institution>
,<addr-line>Turin</addr-line>
,<country>Italy</country>
,</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="Dolcetti, Riccardo" sort="Dolcetti, Riccardo" uniqKey="Dolcetti R" first="Riccardo" last="Dolcetti">Riccardo Dolcetti</name>
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<country xml:lang="fr">Italie</country>
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<author><name sortKey="Giannini, Giuseppe" sort="Giannini, Giuseppe" uniqKey="Giannini G" first="Giuseppe" last="Giannini">Giuseppe Giannini</name>
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,<institution>University La Sapienza</institution>
,<addr-line>Rome</addr-line>
,<country>Italy</country>
,</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="Laura Putignano, Anna" sort="Laura Putignano, Anna" uniqKey="Laura Putignano A" first="Anna" last="Laura Putignano">Anna Laura Putignano</name>
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,<institution>University of Florence</institution>
,<addr-line>Florence</addr-line>
,<country>Italy</country>
,</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<affiliation wicri:level="1"><nlm:aff id="af20"><institution>Fiorgen Foundation for Pharmacogenomics</institution>
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,</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="Varesco, Liliana" sort="Varesco, Liliana" uniqKey="Varesco L" first="Liliana" last="Varesco">Liliana Varesco</name>
<affiliation wicri:level="1"><nlm:aff id="af21"><addr-line>Unit of Hereditary Cancer, Department of Epidemiology, Prevention and Special Functions</addr-line>
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,<addr-line>Genoa</addr-line>
,<country>Italy</country>
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<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="Radice, Paolo" sort="Radice, Paolo" uniqKey="Radice P" first="Paolo" last="Radice">Paolo Radice</name>
<affiliation><nlm:aff wicri:cut=" and" id="af9"><addr-line>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine</addr-line>
</nlm:aff>
<wicri:noCountry code="subfield">Department of Preventive and Predictive Medicine</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Mai, Phuong L" sort="Mai, Phuong L" uniqKey="Mai P" first="Phuong L." last="Mai">Phuong L. Mai</name>
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,<institution>US National Cancer Institute</institution>
,<addr-line>Rockville MD</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Greene, Mark H" sort="Greene, Mark H" uniqKey="Greene M" first="Mark H." last="Greene">Mark H. Greene</name>
<affiliation wicri:level="1"><nlm:aff id="af22"><addr-line>Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics</addr-line>
,<institution>US National Cancer Institute</institution>
,<addr-line>Rockville MD</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L." last="Andrulis">Irene L. Andrulis</name>
<affiliation wicri:level="1"><nlm:aff id="af23"><institution>Samuel Lunenfeld Research Institute, Mount Sinai Hospital</institution>
,<addr-line>Toronto, ON</addr-line>
,<country>Canada</country>
,</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation><nlm:aff id="af24"><addr-line>Department of Molecular Genetics</addr-line>
,</nlm:aff>
</affiliation>
<affiliation><nlm:aff wicri:cut=" and" id="af25"><addr-line>Department of Laboratory Medicine and Pathobiology</addr-line>
</nlm:aff>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af27"><institution>Cancer Care Ontario</institution>
,<addr-line>Toronto, ON</addr-line>
,<country>Canada</country>
,</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Glendon, Gord" sort="Glendon, Gord" uniqKey="Glendon G" first="Gord" last="Glendon">Gord Glendon</name>
<affiliation wicri:level="1"><nlm:aff id="af27"><institution>Cancer Care Ontario</institution>
,<addr-line>Toronto, ON</addr-line>
,<country>Canada</country>
,</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ozcelik, Hilmi" sort="Ozcelik, Hilmi" uniqKey="Ozcelik H" first="Hilmi" last="Ozcelik">Hilmi Ozcelik</name>
<affiliation wicri:level="1"><nlm:aff id="af23"><institution>Samuel Lunenfeld Research Institute, Mount Sinai Hospital</institution>
,<addr-line>Toronto, ON</addr-line>
,<country>Canada</country>
,</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af26"><addr-line>Department of Laboratory Medicine and Pathobiology</addr-line>
,<institution>University of Toronto</institution>
,<addr-line>Toronto, ON</addr-line>
,<country>Canada</country>
,</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Thomassen, Mads" sort="Thomassen, Mads" uniqKey="Thomassen M" first="Mads" last="Thomassen">Mads Thomassen</name>
<affiliation wicri:level="1"><nlm:aff id="af28"><addr-line>Clinical Genetics</addr-line>
,<institution>Odense University Hospital</institution>
,<addr-line>Odense C</addr-line>
,<country>Denmark</country>
,</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gerdes, Anne Marie" sort="Gerdes, Anne Marie" uniqKey="Gerdes A" first="Anne-Marie" last="Gerdes">Anne-Marie Gerdes</name>
<affiliation wicri:level="1"><nlm:aff id="af29"><addr-line>Clinical Genetics</addr-line>
,<institution>Rigshospital</institution>
,<addr-line>Copenhagen</addr-line>
,<country>Denmark</country>
,</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kruse, Torben A" sort="Kruse, Torben A" uniqKey="Kruse T" first="Torben A." last="Kruse">Torben A. Kruse</name>
<affiliation wicri:level="1"><nlm:aff id="af28"><addr-line>Clinical Genetics</addr-line>
,<institution>Odense University Hospital</institution>
,<addr-line>Odense C</addr-line>
,<country>Denmark</country>
,</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Birk Jensen, Uffe" sort="Birk Jensen, Uffe" uniqKey="Birk Jensen U" first="Uffe" last="Birk Jensen">Uffe Birk Jensen</name>
<affiliation wicri:level="1"><nlm:aff id="af30"><addr-line>Clinical Genetics</addr-line>
,<institution>Aarhus University Hospital</institution>
,<addr-line>Aarhus</addr-line>
,<country>Denmark</country>
,</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Cruger, Dorthe G" sort="Cruger, Dorthe G" uniqKey="Cruger D" first="Dorthe G." last="Crüger">Dorthe G. Crüger</name>
<affiliation wicri:level="1"><nlm:aff id="af31"><addr-line>Clinical Genetics</addr-line>
,<institution>Vejle Hospital</institution>
,<addr-line>Vejle</addr-line>
,<country>Denmark</country>
,</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Caligo, Maria A" sort="Caligo, Maria A" uniqKey="Caligo M" first="Maria A." last="Caligo">Maria A. Caligo</name>
<affiliation wicri:level="1"><nlm:aff id="af32"><addr-line>Section of Genetic Oncology, Department of Laboratory Medicine</addr-line>
,<institution>University and University Hospital of Pisa</institution>
,<addr-line>Pisa</addr-line>
,<country>Italy</country>
,</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Laitman, Yael" sort="Laitman, Yael" uniqKey="Laitman Y" first="Yael" last="Laitman">Yael Laitman</name>
<affiliation wicri:level="1"><nlm:aff id="af33"><addr-line>The Susanne Levy Gertner Oncogenetics Unit</addr-line>
,<institution>Sheba Medical Center</institution>
,<addr-line>Tel Hashomer</addr-line>
,<country>Israel</country>
,</nlm:aff>
<country xml:lang="fr">Israël</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Milgrom, Roni" sort="Milgrom, Roni" uniqKey="Milgrom R" first="Roni" last="Milgrom">Roni Milgrom</name>
<affiliation wicri:level="1"><nlm:aff id="af33"><addr-line>The Susanne Levy Gertner Oncogenetics Unit</addr-line>
,<institution>Sheba Medical Center</institution>
,<addr-line>Tel Hashomer</addr-line>
,<country>Israel</country>
,</nlm:aff>
<country xml:lang="fr">Israël</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kaufman, Bella" sort="Kaufman, Bella" uniqKey="Kaufman B" first="Bella" last="Kaufman">Bella Kaufman</name>
<affiliation wicri:level="1"><nlm:aff id="af34"><addr-line>The Breast cancer Unit</addr-line>
,<institution>Institute of Oncology, Sheba Medical Center</institution>
,<addr-line>Tel-Hashomer</addr-line>
,<country>Israel</country>
,</nlm:aff>
<country xml:lang="fr">Israël</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Paluch Shimon, Shani" sort="Paluch Shimon, Shani" uniqKey="Paluch Shimon S" first="Shani" last="Paluch-Shimon">Shani Paluch-Shimon</name>
<affiliation wicri:level="1"><nlm:aff id="af34"><addr-line>The Breast cancer Unit</addr-line>
,<institution>Institute of Oncology, Sheba Medical Center</institution>
,<addr-line>Tel-Hashomer</addr-line>
,<country>Israel</country>
,</nlm:aff>
<country xml:lang="fr">Israël</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Friedman, Eitan" sort="Friedman, Eitan" uniqKey="Friedman E" first="Eitan" last="Friedman">Eitan Friedman</name>
<affiliation wicri:level="1"><nlm:aff id="af33"><addr-line>The Susanne Levy Gertner Oncogenetics Unit</addr-line>
,<institution>Sheba Medical Center</institution>
,<addr-line>Tel Hashomer</addr-line>
,<country>Israel</country>
,</nlm:aff>
<country xml:lang="fr">Israël</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Loman, Niklas" sort="Loman, Niklas" uniqKey="Loman N" first="Niklas" last="Loman">Niklas Loman</name>
<affiliation wicri:level="1"><nlm:aff id="af35"><addr-line>Department of Oncology</addr-line>
,<institution>Lund University Hospital</institution>
,<addr-line>Lund</addr-line>
,<country>Sweden</country>
,</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Harbst, Katja" sort="Harbst, Katja" uniqKey="Harbst K" first="Katja" last="Harbst">Katja Harbst</name>
<affiliation wicri:level="1"><nlm:aff id="af35"><addr-line>Department of Oncology</addr-line>
,<institution>Lund University Hospital</institution>
,<addr-line>Lund</addr-line>
,<country>Sweden</country>
,</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lindblom, Annika" sort="Lindblom, Annika" uniqKey="Lindblom A" first="Annika" last="Lindblom">Annika Lindblom</name>
<affiliation><nlm:aff wicri:cut=" and" id="af36"><addr-line>Department of Clinical Genetics</addr-line>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Arver, Brita" sort="Arver, Brita" uniqKey="Arver B" first="Brita" last="Arver">Brita Arver</name>
<affiliation wicri:level="1"><nlm:aff id="af37"><addr-line>Department of Oncology</addr-line>
,<institution>Karolinska University Hospital</institution>
,<addr-line>S-17176 Stockholm</addr-line>
,<country>Sweden</country>
,</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ehrencrona, Hans" sort="Ehrencrona, Hans" uniqKey="Ehrencrona H" first="Hans" last="Ehrencrona">Hans Ehrencrona</name>
<affiliation wicri:level="1"><nlm:aff id="af38"><addr-line>Department of Genetics and Pathology</addr-line>
,<institution>Rudbeck Laboratory, Uppsala University</institution>
,<addr-line>S-751 85 Uppsala</addr-line>
,<country>Sweden</country>
,</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Melin, Beatrice" sort="Melin, Beatrice" uniqKey="Melin B" first="Beatrice" last="Melin">Beatrice Melin</name>
<affiliation wicri:level="1"><nlm:aff id="af39"><addr-line>Department of Radiation Sciences</addr-line>
,<institution>Oncology, Umeå University</institution>
,<addr-line>S-901 85 Umeå</addr-line>
,<country>Sweden</country>
,</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Nathanson, Katherine L" sort="Nathanson, Katherine L" uniqKey="Nathanson K" first="Katherine L." last="Nathanson">Katherine L. Nathanson</name>
<affiliation wicri:level="1"><nlm:aff id="af40"><institution>University of Pennsylvania</institution>
,<addr-line>Philadelphia, PA</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Domchek, Susan M" sort="Domchek, Susan M" uniqKey="Domchek S" first="Susan M." last="Domchek">Susan M. Domchek</name>
<affiliation wicri:level="1"><nlm:aff id="af40"><institution>University of Pennsylvania</institution>
,<addr-line>Philadelphia, PA</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rebbeck, Timothy" sort="Rebbeck, Timothy" uniqKey="Rebbeck T" first="Timothy" last="Rebbeck">Timothy Rebbeck</name>
<affiliation wicri:level="1"><nlm:aff id="af40"><institution>University of Pennsylvania</institution>
,<addr-line>Philadelphia, PA</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Jakubowska, Ania" sort="Jakubowska, Ania" uniqKey="Jakubowska A" first="Ania" last="Jakubowska">Ania Jakubowska</name>
<affiliation wicri:level="1"><nlm:aff id="af41"><addr-line>International Hereditary Cancer Centre, Department of Genetics and Pathology</addr-line>
,<institution>Pomeranian Medical University</institution>
,<addr-line>Szczecin</addr-line>
,<country>Poland</country>
,</nlm:aff>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lubinski, Jan" sort="Lubinski, Jan" uniqKey="Lubinski J" first="Jan" last="Lubinski">Jan Lubinski</name>
<affiliation wicri:level="1"><nlm:aff id="af41"><addr-line>International Hereditary Cancer Centre, Department of Genetics and Pathology</addr-line>
,<institution>Pomeranian Medical University</institution>
,<addr-line>Szczecin</addr-line>
,<country>Poland</country>
,</nlm:aff>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gronwald, Jacek" sort="Gronwald, Jacek" uniqKey="Gronwald J" first="Jacek" last="Gronwald">Jacek Gronwald</name>
<affiliation wicri:level="1"><nlm:aff id="af41"><addr-line>International Hereditary Cancer Centre, Department of Genetics and Pathology</addr-line>
,<institution>Pomeranian Medical University</institution>
,<addr-line>Szczecin</addr-line>
,<country>Poland</country>
,</nlm:aff>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Huzarski, Tomasz" sort="Huzarski, Tomasz" uniqKey="Huzarski T" first="Tomasz" last="Huzarski">Tomasz Huzarski</name>
<affiliation wicri:level="1"><nlm:aff id="af41"><addr-line>International Hereditary Cancer Centre, Department of Genetics and Pathology</addr-line>
,<institution>Pomeranian Medical University</institution>
,<addr-line>Szczecin</addr-line>
,<country>Poland</country>
,</nlm:aff>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Byrski, Tomasz" sort="Byrski, Tomasz" uniqKey="Byrski T" first="Tomasz" last="Byrski">Tomasz Byrski</name>
<affiliation wicri:level="1"><nlm:aff id="af41"><addr-line>International Hereditary Cancer Centre, Department of Genetics and Pathology</addr-line>
,<institution>Pomeranian Medical University</institution>
,<addr-line>Szczecin</addr-line>
,<country>Poland</country>
,</nlm:aff>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Cybulski, Cezary" sort="Cybulski, Cezary" uniqKey="Cybulski C" first="Cezary" last="Cybulski">Cezary Cybulski</name>
<affiliation wicri:level="1"><nlm:aff id="af41"><addr-line>International Hereditary Cancer Centre, Department of Genetics and Pathology</addr-line>
,<institution>Pomeranian Medical University</institution>
,<addr-line>Szczecin</addr-line>
,<country>Poland</country>
,</nlm:aff>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gorski, Bohdan" sort="Gorski, Bohdan" uniqKey="Gorski B" first="Bohdan" last="Gorski">Bohdan Gorski</name>
<affiliation wicri:level="1"><nlm:aff id="af41"><addr-line>International Hereditary Cancer Centre, Department of Genetics and Pathology</addr-line>
,<institution>Pomeranian Medical University</institution>
,<addr-line>Szczecin</addr-line>
,<country>Poland</country>
,</nlm:aff>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Osorio, Ana" sort="Osorio, Ana" uniqKey="Osorio A" first="Ana" last="Osorio">Ana Osorio</name>
<affiliation wicri:level="1"><nlm:aff id="af42"><addr-line>Human Genetics Group, Human Cancer Genetics Programme</addr-line>
,<institution>Spanish National Cancer Research Centre</institution>
,<addr-line>Madrid</addr-line>
,<country>Spain</country>
,</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation><nlm:aff id="af43"><addr-line>Spanish Network on Rare Diseases (CIBERER)</addr-line>
,</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ram N Y Cajal, Teresa" sort="Ram N Y Cajal, Teresa" uniqKey="Ram N Y Cajal T" first="Teresa" last="Ram N Y Cajal">Teresa Ram N Y Cajal</name>
<affiliation wicri:level="1"><nlm:aff id="af44"><addr-line>Oncology Service</addr-line>
,<institution>Hospital de la Santa Creu i Sant Pau</institution>
,<addr-line>Barcelona</addr-line>
,<country>Spain</country>
,</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Fostira, Florentia" sort="Fostira, Florentia" uniqKey="Fostira F" first="Florentia" last="Fostira">Florentia Fostira</name>
<affiliation wicri:level="1"><nlm:aff id="af45"><addr-line>Molecular Diagnostics Laboratory</addr-line>
,<institution>I.R.R.P., National Center for Scientific Research ‘Demokritos’</institution>
,<addr-line>Athens</addr-line>
,<country>Greece</country>
,</nlm:aff>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Andres, Raquel" sort="Andres, Raquel" uniqKey="Andres R" first="Raquel" last="Andrés">Raquel Andrés</name>
<affiliation wicri:level="1"><nlm:aff id="af46"><addr-line>Oncology unit</addr-line>
,<institution>Hospital clinico Universitario "Lozano Blesa"</institution>
,<addr-line>Zaragoza</addr-line>
,<country>Spain</country>
,</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Benitez, Javier" sort="Benitez, Javier" uniqKey="Benitez J" first="Javier" last="Benitez">Javier Benitez</name>
<affiliation wicri:level="1"><nlm:aff id="af42"><addr-line>Human Genetics Group, Human Cancer Genetics Programme</addr-line>
,<institution>Spanish National Cancer Research Centre</institution>
,<addr-line>Madrid</addr-line>
,<country>Spain</country>
,</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation><nlm:aff id="af43"><addr-line>Spanish Network on Rare Diseases (CIBERER)</addr-line>
,</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hamann, Ute" sort="Hamann, Ute" uniqKey="Hamann U" first="Ute" last="Hamann">Ute Hamann</name>
<affiliation wicri:level="1"><nlm:aff id="af47"><addr-line>Molecular Genetics of Breast Cancer</addr-line>
,<institution>Deutsches Krebsforschungszentrum (DKFZ)</institution>
,<addr-line>Heidelberg</addr-line>
,<country>Germany</country>
,</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hogervorst, Frans B" sort="Hogervorst, Frans B" uniqKey="Hogervorst F" first="Frans B." last="Hogervorst">Frans B. Hogervorst</name>
<affiliation><nlm:aff wicri:cut=" and" id="af48"><addr-line>Family Cancer Clinic</addr-line>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rookus, Matti A" sort="Rookus, Matti A" uniqKey="Rookus M" first="Matti A." last="Rookus">Matti A. Rookus</name>
<affiliation wicri:level="1"><nlm:aff id="af49"><addr-line>Department of Epidemiology</addr-line>
,<institution>Netherlands Cancer Institute</institution>
,<addr-line>Amsterdam</addr-line>
,<country>The Netherlands</country>
,</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hooning, Maartje J" sort="Hooning, Maartje J" uniqKey="Hooning M" first="Maartje J." last="Hooning">Maartje J. Hooning</name>
<affiliation wicri:level="1"><nlm:aff id="af50"><addr-line>Department of Medical Oncology</addr-line>
,<institution>Family Cancer Clinic, Erasmus University Medical Center</institution>
,<addr-line>Rotterdam</addr-line>
,<country>The Netherlands</country>
,</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Nelen, Marcel R" sort="Nelen, Marcel R" uniqKey="Nelen M" first="Marcel R." last="Nelen">Marcel R. Nelen</name>
<affiliation wicri:level="1"><nlm:aff id="af51"><addr-line>Department of Human Genetics 849</addr-line>
,<institution>Radboud University Nijmegen Medical Centre</institution>
,<addr-line>Nijmegen</addr-line>
,<country>The Netherlands</country>
,</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Der Luijt, Rob B" sort="Van Der Luijt, Rob B" uniqKey="Van Der Luijt R" first="Rob B." last="Van Der Luijt">Rob B. Van Der Luijt</name>
<affiliation wicri:level="1"><nlm:aff id="af52"><addr-line>Department of Medical Genetics</addr-line>
,<institution>University Medical Center Utrecht</institution>
,<addr-line>Utrecht</addr-line>
,<country>The Netherlands</country>
,</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Os, Theo A M" sort="Van Os, Theo A M" uniqKey="Van Os T" first="Theo A. M." last="Van Os">Theo A. M. Van Os</name>
<affiliation wicri:level="1"><nlm:aff id="af53"><addr-line>Department of Clinical Genetics</addr-line>
,<institution>Academic Medical Center</institution>
,<addr-line>Amsterdam</addr-line>
,<country>The Netherlands</country>
,</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Asperen, Christi J" sort="Van Asperen, Christi J" uniqKey="Van Asperen C" first="Christi J." last="Van Asperen">Christi J. Van Asperen</name>
<affiliation><nlm:aff id="af54"><addr-line>Department of Clinical Genetics</addr-line>
,</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Devilee, Peter" sort="Devilee, Peter" uniqKey="Devilee P" first="Peter" last="Devilee">Peter Devilee</name>
<affiliation><nlm:aff wicri:cut=" and" id="af55"><addr-line>Department of Human Genetics</addr-line>
</nlm:aff>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af56"><addr-line>Department of Pathology</addr-line>
,<institution>Leiden University Medical Center Leiden</institution>
,<addr-line>Leiden</addr-line>
,<country>The Netherlands</country>
,</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Meijers Heijboer, Hanne E J" sort="Meijers Heijboer, Hanne E J" uniqKey="Meijers Heijboer H" first="Hanne E. J." last="Meijers-Heijboer">Hanne E. J. Meijers-Heijboer</name>
<affiliation wicri:level="1"><nlm:aff id="af57"><addr-line>Department of Clinical Genetics</addr-line>
,<institution>VU Medical Center</institution>
,<addr-line>Amsterdam</addr-line>
,<country>The Netherlands</country>
,</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="G Mez Garcia, Encarna B" sort="G Mez Garcia, Encarna B" uniqKey="G Mez Garcia E" first="Encarna B." last="G Mez Garcia">Encarna B. G Mez Garcia</name>
<affiliation><nlm:aff wicri:cut=" and" id="af58"><addr-line>Department of Clinical Genetics and GROM, School for Oncology</addr-line>
</nlm:aff>
<wicri:noCountry code="subfield">School for Oncology</wicri:noCountry>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af59"><addr-line>Developmental Biology</addr-line>
,<institution>MUMC</institution>
,<addr-line>Maastricht</addr-line>
,<country>The Netherlands</country>
,</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Peock, Susan" sort="Peock, Susan" uniqKey="Peock S" first="Susan" last="Peock">Susan Peock</name>
<affiliation><nlm:aff wicri:cut=" and" id="af1"><addr-line>Department of Public Health and Primary Care</addr-line>
,<institution>Centre for Cancer Genetic Epidemiology</institution>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Cook, Margaret" sort="Cook, Margaret" uniqKey="Cook M" first="Margaret" last="Cook">Margaret Cook</name>
<affiliation><nlm:aff wicri:cut=" and" id="af1"><addr-line>Department of Public Health and Primary Care</addr-line>
,<institution>Centre for Cancer Genetic Epidemiology</institution>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Frost, Debra" sort="Frost, Debra" uniqKey="Frost D" first="Debra" last="Frost">Debra Frost</name>
<affiliation><nlm:aff wicri:cut=" and" id="af1"><addr-line>Department of Public Health and Primary Care</addr-line>
,<institution>Centre for Cancer Genetic Epidemiology</institution>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Platte, Radka" sort="Platte, Radka" uniqKey="Platte R" first="Radka" last="Platte">Radka Platte</name>
<affiliation><nlm:aff wicri:cut=" and" id="af1"><addr-line>Department of Public Health and Primary Care</addr-line>
,<institution>Centre for Cancer Genetic Epidemiology</institution>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Leyland, Jean" sort="Leyland, Jean" uniqKey="Leyland J" first="Jean" last="Leyland">Jean Leyland</name>
<affiliation><nlm:aff wicri:cut=" and" id="af1"><addr-line>Department of Public Health and Primary Care</addr-line>
,<institution>Centre for Cancer Genetic Epidemiology</institution>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Gareth Evans, D" sort="Gareth Evans, D" uniqKey="Gareth Evans D" first="D." last="Gareth Evans">D. Gareth Evans</name>
<affiliation wicri:level="1"><nlm:aff id="af60"><addr-line>Genetic Medicine</addr-line>
,<institution>Manchester Academic Health Sciences Centre, Central Manchester University Hospitals NHS Foundation Trust</institution>
,<addr-line>Manchester</addr-line>
,<country>UK</country>
,</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lalloo, Fiona" sort="Lalloo, Fiona" uniqKey="Lalloo F" first="Fiona" last="Lalloo">Fiona Lalloo</name>
<affiliation wicri:level="1"><nlm:aff id="af60"><addr-line>Genetic Medicine</addr-line>
,<institution>Manchester Academic Health Sciences Centre, Central Manchester University Hospitals NHS Foundation Trust</institution>
,<addr-line>Manchester</addr-line>
,<country>UK</country>
,</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Eeles, Ros" sort="Eeles, Ros" uniqKey="Eeles R" first="Ros" last="Eeles">Ros Eeles</name>
<affiliation wicri:level="1"><nlm:aff id="af61"><addr-line>Oncogenetics Team</addr-line>
,<institution>The Institute of Cancer Research and Royal Marsden NHS Foundation Trust</institution>
,<addr-line>Surrey</addr-line>
,<country>UK</country>
,</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Izatt, Louise" sort="Izatt, Louise" uniqKey="Izatt L" first="Louise" last="Izatt">Louise Izatt</name>
<affiliation wicri:level="1"><nlm:aff id="af62"><addr-line>Clinical Genetics</addr-line>
,<institution>Guy's and St. Thomas’ NHS Foundation Trust</institution>
,<addr-line>London</addr-line>
,<country>UK</country>
,</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Adlard, Julian" sort="Adlard, Julian" uniqKey="Adlard J" first="Julian" last="Adlard">Julian Adlard</name>
<affiliation wicri:level="1"><nlm:aff id="af63"><institution>Yorkshire Regional Genetics Service</institution>
,<addr-line>Leeds</addr-line>
,<country>UK</country>
,</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Davidson, Rosemarie" sort="Davidson, Rosemarie" uniqKey="Davidson R" first="Rosemarie" last="Davidson">Rosemarie Davidson</name>
<affiliation wicri:level="1"><nlm:aff id="af64"><addr-line>Ferguson-Smith Centre for Clinical Genetics</addr-line>
,<institution>Yorkhill Hospitals</institution>
,<addr-line>Glasgow</addr-line>
,<country>UK</country>
,</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Eccles, Diana" sort="Eccles, Diana" uniqKey="Eccles D" first="Diana" last="Eccles">Diana Eccles</name>
<affiliation wicri:level="1"><nlm:aff id="af65"><addr-line>Wessex Clinical Genetics Service</addr-line>
<institution>, Princess Anne Hospital</institution>
,<addr-line>Southampton</addr-line>
,<country>UK</country>
,</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ong, Kai Ren" sort="Ong, Kai Ren" uniqKey="Ong K" first="Kai-Ren" last="Ong">Kai-Ren Ong</name>
<affiliation wicri:level="1"><nlm:aff id="af66"><addr-line>West Midlands Regional Genetics Service</addr-line>
,<institution>Birmingham Women's Hospital Healthcare NHS Trust</institution>
,<addr-line>Edgbaston, Birmingham</addr-line>
,<country>UK</country>
,</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Cook, Jackie" sort="Cook, Jackie" uniqKey="Cook J" first="Jackie" last="Cook">Jackie Cook</name>
<affiliation wicri:level="1"><nlm:aff id="af67"><addr-line>Sheffield Clinical Genetics Service</addr-line>
,<institution>Sheffield Children's Hospital</institution>
,<addr-line>Sheffield</addr-line>
,<country>UK</country>
,</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Douglas, Fiona" sort="Douglas, Fiona" uniqKey="Douglas F" first="Fiona" last="Douglas">Fiona Douglas</name>
<affiliation wicri:level="1"><nlm:aff id="af68"><institution>Institute of Human Genetics, Centre for Life, Newcastle Upon Tyne Hospitals NHS Trust</institution>
,<addr-line>Newcastle upon Tyne</addr-line>
,<country>UK</country>
,</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Paterson, Joan" sort="Paterson, Joan" uniqKey="Paterson J" first="Joan" last="Paterson">Joan Paterson</name>
<affiliation wicri:level="1"><nlm:aff id="af69"><addr-line>Department of Clinical Genetics, East Anglian Regional Genetics Service</addr-line>
,<institution>Addenbrookes Hospital</institution>
,<addr-line>Cambridge</addr-line>
,<country>UK</country>
,</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="John Kennedy, M" sort="John Kennedy, M" uniqKey="John Kennedy M" first="M." last="John Kennedy">M. John Kennedy</name>
<affiliation><nlm:aff id="af70"><addr-line>Academic Unit of Clinical and Molecular Oncology</addr-line>
,<institution>Trinity College Dublin and St James's Hospital</institution>
,<addr-line>Dublin</addr-line>
,<country>Eire</country>
,</nlm:aff>
<wicri:noCountry code="nlm country">Eire</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Miedzybrodzka, Zosia" sort="Miedzybrodzka, Zosia" uniqKey="Miedzybrodzka Z" first="Zosia" last="Miedzybrodzka">Zosia Miedzybrodzka</name>
<affiliation wicri:level="1"><nlm:aff id="af71"><addr-line>North of Scotland Regional Genetics Service</addr-line>
,<institution>NHS Grampian & University of Aberdeen</institution>
,<addr-line>Foresterhill, Aberdeen</addr-line>
,<country>UK</country>
,</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Godwin, Andrew" sort="Godwin, Andrew" uniqKey="Godwin A" first="Andrew" last="Godwin">Andrew Godwin</name>
<affiliation wicri:level="1"><nlm:aff id="af72"><addr-line>Department of Pathology and Laboratory Medicine</addr-line>
,<institution>University of Kansas Medical Center</institution>
,<addr-line>Kansas City</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Stoppa Lyonnet, Dominique" sort="Stoppa Lyonnet, Dominique" uniqKey="Stoppa Lyonnet D" first="Dominique" last="Stoppa-Lyonnet">Dominique Stoppa-Lyonnet</name>
<affiliation><nlm:aff wicri:cut=" and" id="af73"><addr-line>Service de Génétique Oncologique</addr-line>
</nlm:aff>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af74"><addr-line>Unité INSERM U830</addr-line>
,<institution>Institut Curie</institution>
,<addr-line>Paris</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af75"><addr-line>Faculté de Médecine</addr-line>
,<institution>Université Paris Descartes</institution>
,<addr-line>Paris</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Buecher, Bruno" sort="Buecher, Bruno" uniqKey="Buecher B" first="Bruno" last="Buecher">Bruno Buecher</name>
<affiliation><nlm:aff wicri:cut=" and" id="af73"><addr-line>Service de Génétique Oncologique</addr-line>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Belotti, Muriel" sort="Belotti, Muriel" uniqKey="Belotti M" first="Muriel" last="Belotti">Muriel Belotti</name>
<affiliation><nlm:aff wicri:cut=" and" id="af73"><addr-line>Service de Génétique Oncologique</addr-line>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Tirapo, Carole" sort="Tirapo, Carole" uniqKey="Tirapo C" first="Carole" last="Tirapo">Carole Tirapo</name>
<affiliation><nlm:aff wicri:cut=" and" id="af73"><addr-line>Service de Génétique Oncologique</addr-line>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Mazoyer, Sylvie" sort="Mazoyer, Sylvie" uniqKey="Mazoyer S" first="Sylvie" last="Mazoyer">Sylvie Mazoyer</name>
<affiliation wicri:level="1"><nlm:aff id="af4"><addr-line>Equipe labellisée LIGUE 2008, UMR5201 CNRS, Centre Léon Bérard</addr-line>
,<institution>Université de Lyon</institution>
,<addr-line>Lyon</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Barjhoux, Laure" sort="Barjhoux, Laure" uniqKey="Barjhoux L" first="Laure" last="Barjhoux">Laure Barjhoux</name>
<affiliation wicri:level="1"><nlm:aff id="af4"><addr-line>Equipe labellisée LIGUE 2008, UMR5201 CNRS, Centre Léon Bérard</addr-line>
,<institution>Université de Lyon</institution>
,<addr-line>Lyon</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lasset, Christine" sort="Lasset, Christine" uniqKey="Lasset C" first="Christine" last="Lasset">Christine Lasset</name>
<affiliation wicri:level="1"><nlm:aff id="af76"><addr-line>CNRS UMR5558</addr-line>
,<institution>Université Lyon 1</institution>
,<addr-line>Lyon</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af77"><addr-line>Unité de Prévention et d'Epidémiologie Génétique</addr-line>
,<institution>Centre Léon Bérard</institution>
,<addr-line>Lyon</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Leroux, Dominique" sort="Leroux, Dominique" uniqKey="Leroux D" first="Dominique" last="Leroux">Dominique Leroux</name>
<affiliation wicri:level="1"><nlm:aff id="af78"><addr-line>Department of Genetics</addr-line>
,<institution>Centre Hospitalier Universitaire de Grenoble</institution>
,<addr-line>Grenoble</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af79"><institution>Institut Albert Bonniot, Université de Grenoble</institution>
,<addr-line>Grenoble</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Faivre, Laurence" sort="Faivre, Laurence" uniqKey="Faivre L" first="Laurence" last="Faivre">Laurence Faivre</name>
<affiliation wicri:level="1"><nlm:aff id="af80"><addr-line>Centre de Génétique</addr-line>
,<institution>Centre Hospitalier Universitaire de Dijon</institution>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af81"><institution>Centre de Lutte Contre le Cancer Georges François Leclerc</institution>
,<addr-line>Dijon</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bronner, Myriam" sort="Bronner, Myriam" uniqKey="Bronner M" first="Myriam" last="Bronner">Myriam Bronner</name>
<affiliation wicri:level="1"><nlm:aff id="af82"><addr-line>Laboratoire de Génétique Médicale</addr-line>
,<institution>Nancy Université, Centre Hospitalier Régional et Universitaire</institution>
,<addr-line>Vandoeuvre-les-Nancy</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Prieur, Fabienne" sort="Prieur, Fabienne" uniqKey="Prieur F" first="Fabienne" last="Prieur">Fabienne Prieur</name>
<affiliation wicri:level="1"><nlm:aff id="af83"><addr-line>Service de Génétique Clinique Chromosomique et Moléculaire</addr-line>
,<institution>Centre Hospitalier Universitaire de St Etienne</institution>
,<addr-line>St Etienne</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Nogues, Catherine" sort="Nogues, Catherine" uniqKey="Nogues C" first="Catherine" last="Nogues">Catherine Nogues</name>
<affiliation><nlm:aff wicri:cut=" and" id="af84"><addr-line>Oncogénétique Clinique</addr-line>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rouleau, Etienne" sort="Rouleau, Etienne" uniqKey="Rouleau E" first="Etienne" last="Rouleau">Etienne Rouleau</name>
<affiliation wicri:level="1"><nlm:aff id="af85"><addr-line>Laboratoire d'Oncogénétique</addr-line>
,<institution>Hôpital René Huguenin/Institut Curie</institution>
,<addr-line>Saint-Cloud</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pujol, Pascal" sort="Pujol, Pascal" uniqKey="Pujol P" first="Pascal" last="Pujol">Pascal Pujol</name>
<affiliation wicri:level="1"><nlm:aff id="af86"><addr-line>Unité d'Oncogénétique</addr-line>
,<institution>CHU Arnaud de Villeneuve</institution>
,<addr-line>Montpellier</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af87"><addr-line>INSERM 896</addr-line>
,<institution>CRCM Val d'Aurelle</institution>
,<addr-line>Montpellier</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Coupier, Isabelle" sort="Coupier, Isabelle" uniqKey="Coupier I" first="Isabelle" last="Coupier">Isabelle Coupier</name>
<affiliation wicri:level="1"><nlm:aff id="af86"><addr-line>Unité d'Oncogénétique</addr-line>
,<institution>CHU Arnaud de Villeneuve</institution>
,<addr-line>Montpellier</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af88"><addr-line>Unité d'Oncogénétique</addr-line>
,<institution>CRLCC Val d'Aurelle</institution>
,<addr-line>Montpellier</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Frenay, Marc" sort="Frenay, Marc" uniqKey="Frenay M" first="Marc" last="Frénay">Marc Frénay</name>
<affiliation wicri:level="1"><nlm:aff id="af89"><institution>Centre Antoine Lacassagne</institution>
,<addr-line>Nice</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hopper, John L" sort="Hopper, John L" uniqKey="Hopper J" first="John L." last="Hopper">John L. Hopper</name>
<affiliation wicri:level="1"><nlm:aff id="af90"><institution>The University of Melbourne</institution>
,<addr-line>Melbourne</addr-line>
,<country>Australia</country>
,</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Daly, Mary B" sort="Daly, Mary B" uniqKey="Daly M" first="Mary B." last="Daly">Mary B. Daly</name>
<affiliation wicri:level="1"><nlm:aff id="af91"><addr-line>Women's Cancer Program, Department of Medical Oncology</addr-line>
,<institution>Fox Chase Cancer Center</institution>
,<addr-line>Philadelphia, PA</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Terry, Mary B" sort="Terry, Mary B" uniqKey="Terry M" first="Mary B." last="Terry">Mary B. Terry</name>
<affiliation wicri:level="1"><nlm:aff id="af92"><institution>Columbia University New York</institution>
,<addr-line>New York, NY</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="John, Esther M" sort="John, Esther M" uniqKey="John E" first="Esther M." last="John">Esther M. John</name>
<affiliation wicri:level="1"><nlm:aff id="af93"><institution>Cancer Prevention Institute of California (formerly the Northern California Cancer Center)</institution>
,<addr-line>Fremont, CA</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af94"><addr-line>Stanford Cancer Center</addr-line>
,<institution>Stanford University School of Medicine</institution>
,<addr-line>Stanford, CA</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Buys, Saundra S" sort="Buys, Saundra S" uniqKey="Buys S" first="Saundra S." last="Buys">Saundra S. Buys</name>
<affiliation wicri:level="1"><nlm:aff id="af95"><addr-line>Huntsman Cancer Institute</addr-line>
,<institution>University of Utah Health Sciences Centre</institution>
,<addr-line>Salt Lake City, UT</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Yassin, Yosuf" sort="Yassin, Yosuf" uniqKey="Yassin Y" first="Yosuf" last="Yassin">Yosuf Yassin</name>
<affiliation wicri:level="1"><nlm:aff id="af96"><institution>Dana-Farber Cancer Institute</institution>
,<addr-line>Boston, MA</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Miron, Alexander" sort="Miron, Alexander" uniqKey="Miron A" first="Alexander" last="Miron">Alexander Miron</name>
<affiliation wicri:level="1"><nlm:aff id="af96"><institution>Dana-Farber Cancer Institute</institution>
,<addr-line>Boston, MA</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Goldgar, David" sort="Goldgar, David" uniqKey="Goldgar D" first="David" last="Goldgar">David Goldgar</name>
<affiliation wicri:level="1"><nlm:aff id="af97"><addr-line>Department of Dermatology</addr-line>
,<institution>University of Utah</institution>
,<addr-line>Salt Lake City, UT</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Singer, Christian F" sort="Singer, Christian F" uniqKey="Singer C" first="Christian F." last="Singer">Christian F. Singer</name>
<affiliation wicri:level="1"><nlm:aff id="af98"><addr-line>Department of Obstetrics/Gynaecology</addr-line>
,<institution>Medical University of Vienna</institution>
,<addr-line>Vienna</addr-line>
,<country>Austria</country>
,</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tea, Muy Kheng" sort="Tea, Muy Kheng" uniqKey="Tea M" first="Muy-Kheng" last="Tea">Muy-Kheng Tea</name>
<affiliation wicri:level="1"><nlm:aff id="af98"><addr-line>Department of Obstetrics/Gynaecology</addr-line>
,<institution>Medical University of Vienna</institution>
,<addr-line>Vienna</addr-line>
,<country>Austria</country>
,</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pfeiler, Georg" sort="Pfeiler, Georg" uniqKey="Pfeiler G" first="Georg" last="Pfeiler">Georg Pfeiler</name>
<affiliation wicri:level="1"><nlm:aff id="af98"><addr-line>Department of Obstetrics/Gynaecology</addr-line>
,<institution>Medical University of Vienna</institution>
,<addr-line>Vienna</addr-line>
,<country>Austria</country>
,</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Catharina Dressler, Anne" sort="Catharina Dressler, Anne" uniqKey="Catharina Dressler A" first="Anne" last="Catharina Dressler">Anne Catharina Dressler</name>
<affiliation wicri:level="1"><nlm:aff id="af98"><addr-line>Department of Obstetrics/Gynaecology</addr-line>
,<institution>Medical University of Vienna</institution>
,<addr-line>Vienna</addr-line>
,<country>Austria</country>
,</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hansen, Thomas V O" sort="Hansen, Thomas V O" uniqKey="Hansen T" first="Thomas V. O." last="Hansen">Thomas V. O. Hansen</name>
<affiliation><nlm:aff wicri:cut=" and" id="af99"><addr-line>Genomic Medicine, Department of Clinical Biochemistry</addr-line>
</nlm:aff>
<wicri:noCountry code="subfield">Department of Clinical Biochemistry</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="J Nson, Lars" sort="J Nson, Lars" uniqKey="J Nson L" first="Lars" last="J Nson">Lars J Nson</name>
<affiliation><nlm:aff wicri:cut=" and" id="af99"><addr-line>Genomic Medicine, Department of Clinical Biochemistry</addr-line>
</nlm:aff>
<wicri:noCountry code="subfield">Department of Clinical Biochemistry</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Ejlertsen, Bent" sort="Ejlertsen, Bent" uniqKey="Ejlertsen B" first="Bent" last="Ejlertsen">Bent Ejlertsen</name>
<affiliation wicri:level="1"><nlm:aff id="af100"><addr-line>Department of Oncology</addr-line>
,<institution>Rigshospitalet</institution>
,<institution>Copenhagen University Hospital</institution>
,<addr-line>Allerød</addr-line>
,<country>Denmark</country>
,</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bjork Barkardottir, Rosa" sort="Bjork Barkardottir, Rosa" uniqKey="Bjork Barkardottir R" first="Rosa" last="Bjork Barkardottir">Rosa Bjork Barkardottir</name>
<affiliation wicri:level="1"><nlm:aff id="af101"><addr-line>Laboratory of Cell Biology, Department of Pathology</addr-line>
,<institution>Landspitali-University Hospital</institution>
,<addr-line>Tromsø</addr-line>
,<country>Norway,</country>
</nlm:aff>
<wicri:regionArea># see nlm:aff region in country</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af102"><addr-line>Faculty of Medicine</addr-line>
,<institution>University of Iceland</institution>
,<addr-line>Reykjavik</addr-line>
,<country>Iceland</country>
,</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kirchhoff, Tomas" sort="Kirchhoff, Tomas" uniqKey="Kirchhoff T" first="Tomas" last="Kirchhoff">Tomas Kirchhoff</name>
<affiliation wicri:level="1"><nlm:aff id="af103"><addr-line>Clinical Genetics Service, Department of Medicine</addr-line>
,<institution>Memorial Sloan-Kettering Cancer Center</institution>
,<addr-line>New York, NY</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Offit, Kenneth" sort="Offit, Kenneth" uniqKey="Offit K" first="Kenneth" last="Offit">Kenneth Offit</name>
<affiliation wicri:level="1"><nlm:aff id="af103"><addr-line>Clinical Genetics Service, Department of Medicine</addr-line>
,<institution>Memorial Sloan-Kettering Cancer Center</institution>
,<addr-line>New York, NY</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Piedmonte, Marion" sort="Piedmonte, Marion" uniqKey="Piedmonte M" first="Marion" last="Piedmonte">Marion Piedmonte</name>
<affiliation><nlm:aff wicri:cut=" and" id="af104"><addr-line>GOG Statistical and Data Center</addr-line>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rodriguez, Gustavo" sort="Rodriguez, Gustavo" uniqKey="Rodriguez G" first="Gustavo" last="Rodriguez">Gustavo Rodriguez</name>
<affiliation wicri:level="1"><nlm:aff id="af106"><institution>Evanston Northwestern Healthcare</institution>
,<addr-line>Evanston, IL</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Small, Laurie" sort="Small, Laurie" uniqKey="Small L" first="Laurie" last="Small">Laurie Small</name>
<affiliation wicri:level="1"><nlm:aff id="af107"><institution>Maine Medical Center</institution>
,<addr-line>Scarborough, ME</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Boggess, John" sort="Boggess, John" uniqKey="Boggess J" first="John" last="Boggess">John Boggess</name>
<affiliation wicri:level="1"><nlm:aff id="af108"><institution>University of North Carolina</institution>
,<addr-line>Chapel Hill, NC</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Blank, Stephanie" sort="Blank, Stephanie" uniqKey="Blank S" first="Stephanie" last="Blank">Stephanie Blank</name>
<affiliation wicri:level="1"><nlm:aff id="af109"><institution>New York University School of Medicine</institution>
,<addr-line>New York, NY</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Basil, Jack" sort="Basil, Jack" uniqKey="Basil J" first="Jack" last="Basil">Jack Basil</name>
<affiliation wicri:level="1"><nlm:aff id="af110"><institution>St. Elizabeth Medical Center</institution>
,<addr-line>Edgewood, KY</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Azodi, Masoud" sort="Azodi, Masoud" uniqKey="Azodi M" first="Masoud" last="Azodi">Masoud Azodi</name>
<affiliation wicri:level="1"><nlm:aff id="af111"><institution>Yale University School of Medicine</institution>
,<addr-line>New Haven, CT</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ewart Toland, Amanda" sort="Ewart Toland, Amanda" uniqKey="Ewart Toland A" first="Amanda" last="Ewart Toland">Amanda Ewart Toland</name>
<affiliation wicri:level="1"><nlm:aff id="af112"><addr-line>Comprehensive Cancer Center, Department of Molecular Virology, Immunology and Medical Genetics</addr-line>
,<institution>The Ohio State University</institution>
,<addr-line>Columbus, OH</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Montagna, Marco" sort="Montagna, Marco" uniqKey="Montagna M" first="Marco" last="Montagna">Marco Montagna</name>
<affiliation wicri:level="1"><nlm:aff id="af113"><addr-line>Immunology and Molecular Oncology Unit</addr-line>
,<institution>Istituto Oncologico Veneto IOV - IRCCS</institution>
,<addr-line>Padua</addr-line>
,<country>Italy</country>
,</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tognazzo, Silvia" sort="Tognazzo, Silvia" uniqKey="Tognazzo S" first="Silvia" last="Tognazzo">Silvia Tognazzo</name>
<affiliation wicri:level="1"><nlm:aff id="af113"><addr-line>Immunology and Molecular Oncology Unit</addr-line>
,<institution>Istituto Oncologico Veneto IOV - IRCCS</institution>
,<addr-line>Padua</addr-line>
,<country>Italy</country>
,</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Agata, Simona" sort="Agata, Simona" uniqKey="Agata S" first="Simona" last="Agata">Simona Agata</name>
<affiliation wicri:level="1"><nlm:aff id="af113"><addr-line>Immunology and Molecular Oncology Unit</addr-line>
,<institution>Istituto Oncologico Veneto IOV - IRCCS</institution>
,<addr-line>Padua</addr-line>
,<country>Italy</country>
,</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Imyanitov, Evgeny" sort="Imyanitov, Evgeny" uniqKey="Imyanitov E" first="Evgeny" last="Imyanitov">Evgeny Imyanitov</name>
<affiliation wicri:level="1"><nlm:aff id="af114"><institution>N.N. Petrov Institute of Oncology</institution>
,<addr-line>St.-Petersburg</addr-line>
, 197758,<country>Russia</country>
,</nlm:aff>
<country xml:lang="fr">Russie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Janavicius, Ramunas" sort="Janavicius, Ramunas" uniqKey="Janavicius R" first="Ramunas" last="Janavicius">Ramunas Janavicius</name>
<affiliation wicri:level="1"><nlm:aff id="af115"><addr-line>Department of Molecular and Regenerative Medicine</addr-line>
,<institution>Vilnius university hospital Santariskiu Clinics</institution>
,<institution>Hematology</institution>
,<institution>Oncology and Transfusion Medicine Center</institution>
,<addr-line>Vilnius</addr-line>
,<country>Lithuania</country>
,</nlm:aff>
<country xml:lang="fr">Lituanie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af116"><institution>State Research Institute Inovative medicine center</institution>
,<addr-line>Vilnius</addr-line>
,<country>Lithuania</country>
,</nlm:aff>
<country xml:lang="fr">Lituanie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lazaro, Conxi" sort="Lazaro, Conxi" uniqKey="Lazaro C" first="Conxi" last="Lazaro">Conxi Lazaro</name>
<affiliation wicri:level="1"><nlm:aff id="af117"><addr-line>Hereditary Cancer Program</addr-line>
,<institution>Catalan Institute of Oncology</institution>
,<addr-line>Barcelona</addr-line>
,<country>Spain</country>
,</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Blanco, Ignacio" sort="Blanco, Ignacio" uniqKey="Blanco I" first="Ignacio" last="Blanco">Ignacio Blanco</name>
<affiliation wicri:level="1"><nlm:aff id="af117"><addr-line>Hereditary Cancer Program</addr-line>
,<institution>Catalan Institute of Oncology</institution>
,<addr-line>Barcelona</addr-line>
,<country>Spain</country>
,</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pharoah, Paul D P" sort="Pharoah, Paul D P" uniqKey="Pharoah P" first="Paul D. P." last="Pharoah">Paul D. P. Pharoah</name>
<affiliation wicri:level="1"><nlm:aff id="af2"><addr-line>Department of Oncology</addr-line>
,<institution>University of Cambridge</institution>
,<addr-line>Cambridge</addr-line>
,<country>UK</country>
,</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sucheston, Lara" sort="Sucheston, Lara" uniqKey="Sucheston L" first="Lara" last="Sucheston">Lara Sucheston</name>
<affiliation wicri:level="1"><nlm:aff id="af105"><addr-line>Department of Cancer Prevention and Control</addr-line>
,<institution>Roswell Park Cancer Institute</institution>
,<addr-line>Buffalo, NY</addr-line>
14263,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Karlan, Beth Y" sort="Karlan, Beth Y" uniqKey="Karlan B" first="Beth Y." last="Karlan">Beth Y. Karlan</name>
<affiliation wicri:level="1"><nlm:aff id="af118"><institution>Women's Cancer Research Institute at the Samuel Oschin Comprehensive Cancer Institute</institution>
,<institution>Cedars-Sinai Medical Center</institution>
,<addr-line>Los Angeles, CA</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Walsh, Christine S" sort="Walsh, Christine S" uniqKey="Walsh C" first="Christine S." last="Walsh">Christine S. Walsh</name>
<affiliation wicri:level="1"><nlm:aff id="af118"><institution>Women's Cancer Research Institute at the Samuel Oschin Comprehensive Cancer Institute</institution>
,<institution>Cedars-Sinai Medical Center</institution>
,<addr-line>Los Angeles, CA</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Olah, Edith" sort="Olah, Edith" uniqKey="Olah E" first="Edith" last="Olah">Edith Olah</name>
<affiliation wicri:level="1"><nlm:aff id="af119"><addr-line>Department of Molecular Genetics</addr-line>
,<institution>National Institute of Oncology</institution>
,<addr-line>Budapest</addr-line>
,<country>Hungary</country>
,</nlm:aff>
<country xml:lang="fr">Hongrie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bozsik, Aniko" sort="Bozsik, Aniko" uniqKey="Bozsik A" first="Aniko" last="Bozsik">Aniko Bozsik</name>
<affiliation wicri:level="1"><nlm:aff id="af119"><addr-line>Department of Molecular Genetics</addr-line>
,<institution>National Institute of Oncology</institution>
,<addr-line>Budapest</addr-line>
,<country>Hungary</country>
,</nlm:aff>
<country xml:lang="fr">Hongrie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Teo, Soo Hwang" sort="Teo, Soo Hwang" uniqKey="Teo S" first="Soo-Hwang" last="Teo">Soo-Hwang Teo</name>
<affiliation wicri:level="1"><nlm:aff id="af120"><addr-line>Cancer Research Initiatives Foundation</addr-line>
,<institution>Sime Darby Medical Centre</institution>
,<addr-line>Subang Jaya</addr-line>
,<country>Malaysia</country>
,</nlm:aff>
<country xml:lang="fr">Malaisie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af121"><institution>University Malaya Cancer Research Institute</institution>
,<institution>University Malaya</institution>
,<addr-line>Kuala Lumpur</addr-line>
,<country>Malaysia</country>
,</nlm:aff>
<country xml:lang="fr">Malaisie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Seldon, Joyce L" sort="Seldon, Joyce L" uniqKey="Seldon J" first="Joyce L." last="Seldon">Joyce L. Seldon</name>
<affiliation wicri:level="1"><nlm:aff id="af122"><addr-line>UCLA Cancer Genetics Program</addr-line>
,<institution>CLA Jonsson Comp Cancer Center</institution>
,<addr-line>Santa Monica, CA</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Beattie, Mary S" sort="Beattie, Mary S" uniqKey="Beattie M" first="Mary S." last="Beattie">Mary S. Beattie</name>
<affiliation wicri:level="1"><nlm:aff id="af123"><addr-line>UCSF Cancer Risk Program</addr-line>
,<institution>University of California</institution>
,<addr-line>San Francisco, CA</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation><nlm:aff id="af124"><addr-line>UCSF Department of Medicine</addr-line>
,</nlm:aff>
</affiliation>
<affiliation><nlm:aff wicri:cut=" and" id="af125"><addr-line>Department of Epidemiology</addr-line>
</nlm:aff>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af126"><addr-line>Department of Biostatistics</addr-line>
,<institution>University of California</institution>
,<addr-line>San Francisco, CA</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Rensburg, Elizabeth J" sort="Van Rensburg, Elizabeth J" uniqKey="Van Rensburg E" first="Elizabeth J." last="Van Rensburg">Elizabeth J. Van Rensburg</name>
<affiliation wicri:level="1"><nlm:aff id="af127"><addr-line>Department of Genetics</addr-line>
,<institution>University of Pretoria</institution>
,<addr-line>Pretoria</addr-line>
,<country>South Africa</country>
,</nlm:aff>
<country xml:lang="fr">Afrique du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sluiter, Michelle D" sort="Sluiter, Michelle D" uniqKey="Sluiter M" first="Michelle D." last="Sluiter">Michelle D. Sluiter</name>
<affiliation wicri:level="1"><nlm:aff id="af127"><addr-line>Department of Genetics</addr-line>
,<institution>University of Pretoria</institution>
,<addr-line>Pretoria</addr-line>
,<country>South Africa</country>
,</nlm:aff>
<country xml:lang="fr">Afrique du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Diez, Orland" sort="Diez, Orland" uniqKey="Diez O" first="Orland" last="Diez">Orland Diez</name>
<affiliation wicri:level="1"><nlm:aff id="af128"><addr-line>Oncogenetics Laboratory</addr-line>
,<institution>University Hospital Vall d'Hebron</institution>
,<addr-line>Barcelona</addr-line>
,<country>Spain</country>
,</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af129"><institution>Vall d'Hebron Institute of Oncology (VHIO)</institution>
,<addr-line>Barcelona</addr-line>
,<country>Spain</country>
,</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schmutzler, Rita K" sort="Schmutzler, Rita K" uniqKey="Schmutzler R" first="Rita K." last="Schmutzler">Rita K. Schmutzler</name>
<affiliation><nlm:aff wicri:cut=" and" id="af130"><addr-line>Centre of Familial Breast and Ovarian Cancer, Department of Gynaecology and Obstetrics</addr-line>
</nlm:aff>
<wicri:noCountry code="subfield">Department of Gynaecology and Obstetrics</wicri:noCountry>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af131"><addr-line>Centre for Integrated Oncology (CIO)</addr-line>
,<institution>University hospital of Cologne</institution>
,<addr-line>Cologne</addr-line>
,<country>Germany</country>
,</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wappenschmidt, Barbara" sort="Wappenschmidt, Barbara" uniqKey="Wappenschmidt B" first="Barbara" last="Wappenschmidt">Barbara Wappenschmidt</name>
<affiliation><nlm:aff wicri:cut=" and" id="af130"><addr-line>Centre of Familial Breast and Ovarian Cancer, Department of Gynaecology and Obstetrics</addr-line>
</nlm:aff>
<wicri:noCountry code="subfield">Department of Gynaecology and Obstetrics</wicri:noCountry>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af131"><addr-line>Centre for Integrated Oncology (CIO)</addr-line>
,<institution>University hospital of Cologne</institution>
,<addr-line>Cologne</addr-line>
,<country>Germany</country>
,</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Engel, Christoph" sort="Engel, Christoph" uniqKey="Engel C" first="Christoph" last="Engel">Christoph Engel</name>
<affiliation wicri:level="1"><nlm:aff id="af132"><addr-line>Institute for Medical Informatics, Statistics and Epidemiology</addr-line>
,<institution>University of Leipzig</institution>
,<addr-line>Leipzig</addr-line>
,<country>Germany</country>
,</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Meindl, Alfons" sort="Meindl, Alfons" uniqKey="Meindl A" first="Alfons" last="Meindl">Alfons Meindl</name>
<affiliation wicri:level="1"><nlm:aff id="af133"><addr-line>Department of Gynaecology and Obstetrics, Division of Tumor Genetics, Klinikum rechts der Isar</addr-line>
,<institution>Technical University Munich</institution>
,<addr-line>Munich</addr-line>
,<country>Germany</country>
,</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ruehl, Ina" sort="Ruehl, Ina" uniqKey="Ruehl I" first="Ina" last="Ruehl">Ina Ruehl</name>
<affiliation wicri:level="1"><nlm:aff id="af134"><addr-line>Department of Gynaecology and Obstetrics</addr-line>
,<institution>Ludwig-Maximillians University Munich</institution>
,<addr-line>Munich</addr-line>
,<country>Germany</country>
,</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Varon Mateeva, Raymonda" sort="Varon Mateeva, Raymonda" uniqKey="Varon Mateeva R" first="Raymonda" last="Varon-Mateeva">Raymonda Varon-Mateeva</name>
<affiliation wicri:level="1"><nlm:aff id="af135"><institution>Institute of Human Genetics</institution>
,<addr-line>Campus Virchov Klinikum, Charite Berlin</addr-line>
,<country>Germany</country>
,</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kast, Karin" sort="Kast, Karin" uniqKey="Kast K" first="Karin" last="Kast">Karin Kast</name>
<affiliation wicri:level="1"><nlm:aff id="af136"><addr-line>Department of Gynaecology and Obstetrics</addr-line>
,<institution>University Hospital Carl Gustav Carus, Technical University Dresden</institution>
,<addr-line>Dresden</addr-line>
,<country>Germany</country>
,</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Deissler, Helmut" sort="Deissler, Helmut" uniqKey="Deissler H" first="Helmut" last="Deissler">Helmut Deissler</name>
<affiliation wicri:level="1"><nlm:aff id="af137"><addr-line>Department of Gynaecology and Obstetrics</addr-line>
,<institution>University Hospital Ulm</institution>
,<addr-line>Ulm</addr-line>
,<country>Germany</country>
,</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Niederacher, Dieter" sort="Niederacher, Dieter" uniqKey="Niederacher D" first="Dieter" last="Niederacher">Dieter Niederacher</name>
<affiliation wicri:level="1"><nlm:aff id="af138"><addr-line>Department of Gynaecology and Obstetrics</addr-line>
,<institution>University Hospital Düsseldorf, Heinrich-Heine University Düsseldorf</institution>
,<addr-line>Düsseldorf</addr-line>
,<country>Germany</country>
,</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Arnold, Norbert" sort="Arnold, Norbert" uniqKey="Arnold N" first="Norbert" last="Arnold">Norbert Arnold</name>
<affiliation wicri:level="1"><nlm:aff id="af139"><addr-line>Department of Gynaecology and Obstetrics</addr-line>
,<institution>University Hospital of Schleswig-Holstein, Campus Kiel, Christian-Albrechts University Kiel</institution>
,<addr-line>Kiel</addr-line>
,<country>Germany</country>
,</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gadzicki, Dorothea" sort="Gadzicki, Dorothea" uniqKey="Gadzicki D" first="Dorothea" last="Gadzicki">Dorothea Gadzicki</name>
<affiliation wicri:level="1"><nlm:aff id="af140"><institution>Institute of Cell and Molecular Pathology, Hannover Medical School</institution>
,<addr-line>Hannover</addr-line>
,<country>Germany</country>
,</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schonbuchner, Ines" sort="Schonbuchner, Ines" uniqKey="Schonbuchner I" first="Ines" last="Schönbuchner">Ines Schönbuchner</name>
<affiliation wicri:level="1"><nlm:aff id="af141"><addr-line>Centre of Familial Breast and Ovarian Cancer, Department of Medical Genetics</addr-line>
,<institution>Institute of Human Genetics, University Würzburg</institution>
,<addr-line>Würzburg</addr-line>
,<country>Germany</country>
,</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Caldes, Trinidad" sort="Caldes, Trinidad" uniqKey="Caldes T" first="Trinidad" last="Caldes">Trinidad Caldes</name>
<affiliation wicri:level="1"><nlm:aff id="af142"><addr-line>Molecular Oncology Laboratory</addr-line>
,<institution>Hospital Clinico San Carlos</institution>
,<addr-line>Madrid</addr-line>
,<country>Spain</country>
,</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="De La Hoya, Miguel" sort="De La Hoya, Miguel" uniqKey="De La Hoya M" first="Miguel" last="De La Hoya">Miguel De La Hoya</name>
<affiliation wicri:level="1"><nlm:aff id="af142"><addr-line>Molecular Oncology Laboratory</addr-line>
,<institution>Hospital Clinico San Carlos</institution>
,<addr-line>Madrid</addr-line>
,<country>Spain</country>
,</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Nevanlinna, Heli" sort="Nevanlinna, Heli" uniqKey="Nevanlinna H" first="Heli" last="Nevanlinna">Heli Nevanlinna</name>
<affiliation><nlm:aff wicri:cut=" and" id="af143"><addr-line>Department of Obstetrics and Gynecology</addr-line>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Aittom Ki, Kristiina" sort="Aittom Ki, Kristiina" uniqKey="Aittom Ki K" first="Kristiina" last="Aittom Ki">Kristiina Aittom Ki</name>
<affiliation wicri:level="1"><nlm:aff id="af144"><addr-line>Department of Clinical Genetics</addr-line>
,<institution>Helsinki University Central Hospital</institution>
,<addr-line>Helsinki</addr-line>
,<country>Finland</country>
,</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Dumont, Martine" sort="Dumont, Martine" uniqKey="Dumont M" first="Martine" last="Dumont">Martine Dumont</name>
<affiliation><nlm:aff wicri:cut=" and" id="af5"><addr-line>Cancer Genomics Laboratory</addr-line>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Chiquette, Jocelyne" sort="Chiquette, Jocelyne" uniqKey="Chiquette J" first="Jocelyne" last="Chiquette">Jocelyne Chiquette</name>
<affiliation wicri:level="1"><nlm:aff id="af145"><addr-line>Unité de recherche en santé des populations</addr-line>
,<institution>Centre des maladies du sein Deschênes-Fabia, Centre de recherche FRSQ du Centre hospitalier affilié universitaire de Québec</institution>
,<addr-line>Québec, QC</addr-line>
,<country>Canada</country>
,</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tischkowitz, Marc" sort="Tischkowitz, Marc" uniqKey="Tischkowitz M" first="Marc" last="Tischkowitz">Marc Tischkowitz</name>
<affiliation wicri:level="1"><nlm:aff id="af146"><addr-line>Program in Cancer Genetics, Departments of Human Genetics and Oncology</addr-line>
,<institution>McGill University</institution>
,<addr-line>Montreal, QC</addr-line>
,<country>Canada</country>
,</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af147"><institution>Lady Davis Institute, Segal Cancer Centre, Jewish General Hospital</institution>
,<addr-line>Montreal, QC</addr-line>
,<country>Canada</country>
,</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Chen, Xiaoqing" sort="Chen, Xiaoqing" uniqKey="Chen X" first="Xiaoqing" last="Chen">Xiaoqing Chen</name>
<affiliation wicri:level="1"><nlm:aff id="af7"><institution>Queensland Institute of Medical Research</institution>
,<addr-line>Brisbane</addr-line>
,<country>Australia</country>
,</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Beesley, Jonathan" sort="Beesley, Jonathan" uniqKey="Beesley J" first="Jonathan" last="Beesley">Jonathan Beesley</name>
<affiliation wicri:level="1"><nlm:aff id="af7"><institution>Queensland Institute of Medical Research</institution>
,<addr-line>Brisbane</addr-line>
,<country>Australia</country>
,</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Spurdle, Amanda B" sort="Spurdle, Amanda B" uniqKey="Spurdle A" first="Amanda B." last="Spurdle">Amanda B. Spurdle</name>
<affiliation wicri:level="1"><nlm:aff id="af7"><institution>Queensland Institute of Medical Research</institution>
,<addr-line>Brisbane</addr-line>
,<country>Australia</country>
,</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Neuhausen, Susan L" sort="Neuhausen, Susan L" uniqKey="Neuhausen S" first="Susan L." last="Neuhausen">Susan L. Neuhausen</name>
<affiliation wicri:level="1"><nlm:aff id="af148"><addr-line>Department of Population Sciences</addr-line>
,<institution>Beckman Research Institute of the City of Hope</institution>
, Duarte,<addr-line>CA</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Chun Ding, Yuan" sort="Chun Ding, Yuan" uniqKey="Chun Ding Y" first="Yuan" last="Chun Ding">Yuan Chun Ding</name>
<affiliation wicri:level="1"><nlm:aff id="af148"><addr-line>Department of Population Sciences</addr-line>
,<institution>Beckman Research Institute of the City of Hope</institution>
, Duarte,<addr-line>CA</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Fredericksen, Zachary" sort="Fredericksen, Zachary" uniqKey="Fredericksen Z" first="Zachary" last="Fredericksen">Zachary Fredericksen</name>
<affiliation wicri:level="1"><nlm:aff wicri:cut=" and" id="af149"><addr-line>Department of Health Sciences Research</addr-line>
,<institution>Mayo Clinic</institution>
,<addr-line>Rochester, MN</addr-line>
,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wang, Xianshu" sort="Wang, Xianshu" uniqKey="Wang X" first="Xianshu" last="Wang">Xianshu Wang</name>
<affiliation wicri:level="1"><nlm:aff id="af150"><addr-line>Department of Laboratory Medicine and Pathology</addr-line>
,<institution>Mayo Clinic</institution>
,<addr-line>Rochester, MN</addr-line>
,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pankratz, Vernon S" sort="Pankratz, Vernon S" uniqKey="Pankratz V" first="Vernon S." last="Pankratz">Vernon S. Pankratz</name>
<affiliation wicri:level="1"><nlm:aff wicri:cut=" and" id="af149"><addr-line>Department of Health Sciences Research</addr-line>
,<institution>Mayo Clinic</institution>
,<addr-line>Rochester, MN</addr-line>
,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Couch, Fergus" sort="Couch, Fergus" uniqKey="Couch F" first="Fergus" last="Couch">Fergus Couch</name>
<affiliation wicri:level="1"><nlm:aff id="af150"><addr-line>Department of Laboratory Medicine and Pathology</addr-line>
,<institution>Mayo Clinic</institution>
,<addr-line>Rochester, MN</addr-line>
,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Simard, Jacques" sort="Simard, Jacques" uniqKey="Simard J" first="Jacques" last="Simard">Jacques Simard</name>
<affiliation wicri:level="1"><nlm:aff id="af6"><addr-line>Canada Research Chair in Oncogenetics, Cancer Genomics Laboratory</addr-line>
,<institution>Centre Hospitalier Universitaire de Québec and Laval University</institution>
,<addr-line>2705 Laurier Boulevard, T3-57, Quebec City, QC</addr-line>
,<country>Canada</country>
,</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F." last="Easton">Douglas F. Easton</name>
<affiliation><nlm:aff wicri:cut=" and" id="af1"><addr-line>Department of Public Health and Primary Care</addr-line>
,<institution>Centre for Cancer Genetic Epidemiology</institution>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Chenevix Trench, Georgia" sort="Chenevix Trench, Georgia" uniqKey="Chenevix Trench G" first="Georgia" last="Chenevix-Trench">Georgia Chenevix-Trench</name>
<affiliation wicri:level="1"><nlm:aff id="af7"><institution>Queensland Institute of Medical Research</institution>
,<addr-line>Brisbane</addr-line>
,<country>Australia</country>
,</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">21593217</idno>
<idno type="pmc">3652640</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652640</idno>
<idno type="RBID">PMC:3652640</idno>
<idno type="doi">10.1093/hmg/ddr226</idno>
<date when="2011">2011</date>
<idno type="wicri:Area/Pmc/Corpus">001864</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001864</idno>
<idno type="wicri:Area/Pmc/Curation">001724</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001724</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for <italic>BRCA1</italic>
and <italic>BRCA2</italic>
mutation carriers</title>
<author><name sortKey="Antoniou, Antonis C" sort="Antoniou, Antonis C" uniqKey="Antoniou A" first="Antonis C" last="Antoniou">Antonis C. Antoniou</name>
<affiliation><nlm:aff wicri:cut=" and" id="af1"><addr-line>Department of Public Health and Primary Care</addr-line>
,<institution>Centre for Cancer Genetic Epidemiology</institution>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kartsonaki, Christiana" sort="Kartsonaki, Christiana" uniqKey="Kartsonaki C" first="Christiana" last="Kartsonaki">Christiana Kartsonaki</name>
<affiliation><nlm:aff wicri:cut=" and" id="af1"><addr-line>Department of Public Health and Primary Care</addr-line>
,<institution>Centre for Cancer Genetic Epidemiology</institution>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Sinilnikova, Olga M" sort="Sinilnikova, Olga M" uniqKey="Sinilnikova O" first="Olga M." last="Sinilnikova">Olga M. Sinilnikova</name>
<affiliation wicri:level="1"><nlm:aff id="af3"><institution>Centre Hospitalier Universitaire de Lyon/Centre Léon Bérard, Unité Mixte de Génétique Constitutionnelle des Cancers Fréquents</institution>
,<addr-line>Lyon</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af4"><addr-line>Equipe labellisée LIGUE 2008, UMR5201 CNRS, Centre Léon Bérard</addr-line>
,<institution>Université de Lyon</institution>
,<addr-line>Lyon</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Soucy, Penny" sort="Soucy, Penny" uniqKey="Soucy P" first="Penny" last="Soucy">Penny Soucy</name>
<affiliation><nlm:aff wicri:cut=" and" id="af5"><addr-line>Cancer Genomics Laboratory</addr-line>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Mcguffog, Lesley" sort="Mcguffog, Lesley" uniqKey="Mcguffog L" first="Lesley" last="Mcguffog">Lesley Mcguffog</name>
<affiliation><nlm:aff wicri:cut=" and" id="af1"><addr-line>Department of Public Health and Primary Care</addr-line>
,<institution>Centre for Cancer Genetic Epidemiology</institution>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Healey, Sue" sort="Healey, Sue" uniqKey="Healey S" first="Sue" last="Healey">Sue Healey</name>
<affiliation wicri:level="1"><nlm:aff id="af7"><institution>Queensland Institute of Medical Research</institution>
,<addr-line>Brisbane</addr-line>
,<country>Australia</country>
,</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lee, Andrew" sort="Lee, Andrew" uniqKey="Lee A" first="Andrew" last="Lee">Andrew Lee</name>
<affiliation><nlm:aff wicri:cut=" and" id="af1"><addr-line>Department of Public Health and Primary Care</addr-line>
,<institution>Centre for Cancer Genetic Epidemiology</institution>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Peterlongo, Paolo" sort="Peterlongo, Paolo" uniqKey="Peterlongo P" first="Paolo" last="Peterlongo">Paolo Peterlongo</name>
<affiliation><nlm:aff wicri:cut=" and" id="af9"><addr-line>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine</addr-line>
</nlm:aff>
<wicri:noCountry code="subfield">Department of Preventive and Predictive Medicine</wicri:noCountry>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af11"><addr-line>IFOM</addr-line>
,<institution>Fondazione Istituto FIRC di Oncologia Molecolare</institution>
,<addr-line>Milan</addr-line>
,<country>Italy</country>
,</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Manoukian, Siranoush" sort="Manoukian, Siranoush" uniqKey="Manoukian S" first="Siranoush" last="Manoukian">Siranoush Manoukian</name>
<affiliation wicri:level="1"><nlm:aff id="af12"><addr-line>Unit of Medical Genetics, Department of Preventive and Predicted Medicine</addr-line>
,<institution>Fondazione IRCCS Istituto Nazionale Tumori (INT)</institution>
,<addr-line>Milan</addr-line>
,<country>Italy</country>
,</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Peissel, Bernard" sort="Peissel, Bernard" uniqKey="Peissel B" first="Bernard" last="Peissel">Bernard Peissel</name>
<affiliation wicri:level="1"><nlm:aff id="af12"><addr-line>Unit of Medical Genetics, Department of Preventive and Predicted Medicine</addr-line>
,<institution>Fondazione IRCCS Istituto Nazionale Tumori (INT)</institution>
,<addr-line>Milan</addr-line>
,<country>Italy</country>
,</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Zaffaroni, Daniela" sort="Zaffaroni, Daniela" uniqKey="Zaffaroni D" first="Daniela" last="Zaffaroni">Daniela Zaffaroni</name>
<affiliation wicri:level="1"><nlm:aff id="af12"><addr-line>Unit of Medical Genetics, Department of Preventive and Predicted Medicine</addr-line>
,<institution>Fondazione IRCCS Istituto Nazionale Tumori (INT)</institution>
,<addr-line>Milan</addr-line>
,<country>Italy</country>
,</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Cattaneo, Elisa" sort="Cattaneo, Elisa" uniqKey="Cattaneo E" first="Elisa" last="Cattaneo">Elisa Cattaneo</name>
<affiliation wicri:level="1"><nlm:aff id="af10"><addr-line>Unit of Medical Genetics, Department of Preventive and Predicted Medicine</addr-line>
,<institution>Fondazione IRCCS Istituto Nazionale Tumori (INT)</institution>
,<addr-line>Milan</addr-line>
,<country>Italy</country>
,</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Barile, Monica" sort="Barile, Monica" uniqKey="Barile M" first="Monica" last="Barile">Monica Barile</name>
<affiliation wicri:level="1"><nlm:aff id="af14"><addr-line>Division of Cancer Prevention and Genetics</addr-line>
,<institution>Istituto Europeo di Oncologia (IEO)</institution>
,<addr-line>Milan</addr-line>
,<country>Italy</country>
,</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pensotti, Valeria" sort="Pensotti, Valeria" uniqKey="Pensotti V" first="Valeria" last="Pensotti">Valeria Pensotti</name>
<affiliation wicri:level="1"><nlm:aff id="af15"><addr-line>Cogentech</addr-line>
,<institution>Consortium for Genomics Technology</institution>
,<addr-line>Milan</addr-line>
,<country>Italy</country>
,</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pasini, Barbara" sort="Pasini, Barbara" uniqKey="Pasini B" first="Barbara" last="Pasini">Barbara Pasini</name>
<affiliation wicri:level="1"><nlm:aff id="af16"><addr-line>Department of Genetics, Biology and Biochemistry</addr-line>
,<institution>University of Turin</institution>
,<addr-line>Turin</addr-line>
,<country>Italy</country>
,</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Dolcetti, Riccardo" sort="Dolcetti, Riccardo" uniqKey="Dolcetti R" first="Riccardo" last="Dolcetti">Riccardo Dolcetti</name>
<affiliation wicri:level="1"><nlm:aff id="af17"><addr-line>Cancer Bioimmunotherapy Unit</addr-line>
,<institution>Centro di Riferimento Oncologico, IRCCS</institution>
,<addr-line>Aviano (PN)</addr-line>
,<country>Italy</country>
,</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Giannini, Giuseppe" sort="Giannini, Giuseppe" uniqKey="Giannini G" first="Giuseppe" last="Giannini">Giuseppe Giannini</name>
<affiliation wicri:level="1"><nlm:aff id="af18"><addr-line>Department of Experimental Medicine</addr-line>
,<institution>University La Sapienza</institution>
,<addr-line>Rome</addr-line>
,<country>Italy</country>
,</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Laura Putignano, Anna" sort="Laura Putignano, Anna" uniqKey="Laura Putignano A" first="Anna" last="Laura Putignano">Anna Laura Putignano</name>
<affiliation wicri:level="1"><nlm:aff id="af19"><addr-line>Department of Clinical Physiopathology</addr-line>
,<institution>University of Florence</institution>
,<addr-line>Florence</addr-line>
,<country>Italy</country>
,</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af20"><institution>Fiorgen Foundation for Pharmacogenomics</institution>
,<addr-line>Sesto Fiorentino</addr-line>
,<country>Italy</country>
,</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Varesco, Liliana" sort="Varesco, Liliana" uniqKey="Varesco L" first="Liliana" last="Varesco">Liliana Varesco</name>
<affiliation wicri:level="1"><nlm:aff id="af21"><addr-line>Unit of Hereditary Cancer, Department of Epidemiology, Prevention and Special Functions</addr-line>
,<institution>Istituto Nazionale per la Ricerca sul Cancro (IST)</institution>
,<addr-line>Genoa</addr-line>
,<country>Italy</country>
,</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Radice, Paolo" sort="Radice, Paolo" uniqKey="Radice P" first="Paolo" last="Radice">Paolo Radice</name>
<affiliation><nlm:aff wicri:cut=" and" id="af9"><addr-line>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine</addr-line>
</nlm:aff>
<wicri:noCountry code="subfield">Department of Preventive and Predictive Medicine</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Mai, Phuong L" sort="Mai, Phuong L" uniqKey="Mai P" first="Phuong L." last="Mai">Phuong L. Mai</name>
<affiliation wicri:level="1"><nlm:aff id="af22"><addr-line>Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics</addr-line>
,<institution>US National Cancer Institute</institution>
,<addr-line>Rockville MD</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Greene, Mark H" sort="Greene, Mark H" uniqKey="Greene M" first="Mark H." last="Greene">Mark H. Greene</name>
<affiliation wicri:level="1"><nlm:aff id="af22"><addr-line>Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics</addr-line>
,<institution>US National Cancer Institute</institution>
,<addr-line>Rockville MD</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L." last="Andrulis">Irene L. Andrulis</name>
<affiliation wicri:level="1"><nlm:aff id="af23"><institution>Samuel Lunenfeld Research Institute, Mount Sinai Hospital</institution>
,<addr-line>Toronto, ON</addr-line>
,<country>Canada</country>
,</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation><nlm:aff id="af24"><addr-line>Department of Molecular Genetics</addr-line>
,</nlm:aff>
</affiliation>
<affiliation><nlm:aff wicri:cut=" and" id="af25"><addr-line>Department of Laboratory Medicine and Pathobiology</addr-line>
</nlm:aff>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af27"><institution>Cancer Care Ontario</institution>
,<addr-line>Toronto, ON</addr-line>
,<country>Canada</country>
,</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Glendon, Gord" sort="Glendon, Gord" uniqKey="Glendon G" first="Gord" last="Glendon">Gord Glendon</name>
<affiliation wicri:level="1"><nlm:aff id="af27"><institution>Cancer Care Ontario</institution>
,<addr-line>Toronto, ON</addr-line>
,<country>Canada</country>
,</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ozcelik, Hilmi" sort="Ozcelik, Hilmi" uniqKey="Ozcelik H" first="Hilmi" last="Ozcelik">Hilmi Ozcelik</name>
<affiliation wicri:level="1"><nlm:aff id="af23"><institution>Samuel Lunenfeld Research Institute, Mount Sinai Hospital</institution>
,<addr-line>Toronto, ON</addr-line>
,<country>Canada</country>
,</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af26"><addr-line>Department of Laboratory Medicine and Pathobiology</addr-line>
,<institution>University of Toronto</institution>
,<addr-line>Toronto, ON</addr-line>
,<country>Canada</country>
,</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Thomassen, Mads" sort="Thomassen, Mads" uniqKey="Thomassen M" first="Mads" last="Thomassen">Mads Thomassen</name>
<affiliation wicri:level="1"><nlm:aff id="af28"><addr-line>Clinical Genetics</addr-line>
,<institution>Odense University Hospital</institution>
,<addr-line>Odense C</addr-line>
,<country>Denmark</country>
,</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gerdes, Anne Marie" sort="Gerdes, Anne Marie" uniqKey="Gerdes A" first="Anne-Marie" last="Gerdes">Anne-Marie Gerdes</name>
<affiliation wicri:level="1"><nlm:aff id="af29"><addr-line>Clinical Genetics</addr-line>
,<institution>Rigshospital</institution>
,<addr-line>Copenhagen</addr-line>
,<country>Denmark</country>
,</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kruse, Torben A" sort="Kruse, Torben A" uniqKey="Kruse T" first="Torben A." last="Kruse">Torben A. Kruse</name>
<affiliation wicri:level="1"><nlm:aff id="af28"><addr-line>Clinical Genetics</addr-line>
,<institution>Odense University Hospital</institution>
,<addr-line>Odense C</addr-line>
,<country>Denmark</country>
,</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Birk Jensen, Uffe" sort="Birk Jensen, Uffe" uniqKey="Birk Jensen U" first="Uffe" last="Birk Jensen">Uffe Birk Jensen</name>
<affiliation wicri:level="1"><nlm:aff id="af30"><addr-line>Clinical Genetics</addr-line>
,<institution>Aarhus University Hospital</institution>
,<addr-line>Aarhus</addr-line>
,<country>Denmark</country>
,</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Cruger, Dorthe G" sort="Cruger, Dorthe G" uniqKey="Cruger D" first="Dorthe G." last="Crüger">Dorthe G. Crüger</name>
<affiliation wicri:level="1"><nlm:aff id="af31"><addr-line>Clinical Genetics</addr-line>
,<institution>Vejle Hospital</institution>
,<addr-line>Vejle</addr-line>
,<country>Denmark</country>
,</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Caligo, Maria A" sort="Caligo, Maria A" uniqKey="Caligo M" first="Maria A." last="Caligo">Maria A. Caligo</name>
<affiliation wicri:level="1"><nlm:aff id="af32"><addr-line>Section of Genetic Oncology, Department of Laboratory Medicine</addr-line>
,<institution>University and University Hospital of Pisa</institution>
,<addr-line>Pisa</addr-line>
,<country>Italy</country>
,</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Laitman, Yael" sort="Laitman, Yael" uniqKey="Laitman Y" first="Yael" last="Laitman">Yael Laitman</name>
<affiliation wicri:level="1"><nlm:aff id="af33"><addr-line>The Susanne Levy Gertner Oncogenetics Unit</addr-line>
,<institution>Sheba Medical Center</institution>
,<addr-line>Tel Hashomer</addr-line>
,<country>Israel</country>
,</nlm:aff>
<country xml:lang="fr">Israël</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Milgrom, Roni" sort="Milgrom, Roni" uniqKey="Milgrom R" first="Roni" last="Milgrom">Roni Milgrom</name>
<affiliation wicri:level="1"><nlm:aff id="af33"><addr-line>The Susanne Levy Gertner Oncogenetics Unit</addr-line>
,<institution>Sheba Medical Center</institution>
,<addr-line>Tel Hashomer</addr-line>
,<country>Israel</country>
,</nlm:aff>
<country xml:lang="fr">Israël</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kaufman, Bella" sort="Kaufman, Bella" uniqKey="Kaufman B" first="Bella" last="Kaufman">Bella Kaufman</name>
<affiliation wicri:level="1"><nlm:aff id="af34"><addr-line>The Breast cancer Unit</addr-line>
,<institution>Institute of Oncology, Sheba Medical Center</institution>
,<addr-line>Tel-Hashomer</addr-line>
,<country>Israel</country>
,</nlm:aff>
<country xml:lang="fr">Israël</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Paluch Shimon, Shani" sort="Paluch Shimon, Shani" uniqKey="Paluch Shimon S" first="Shani" last="Paluch-Shimon">Shani Paluch-Shimon</name>
<affiliation wicri:level="1"><nlm:aff id="af34"><addr-line>The Breast cancer Unit</addr-line>
,<institution>Institute of Oncology, Sheba Medical Center</institution>
,<addr-line>Tel-Hashomer</addr-line>
,<country>Israel</country>
,</nlm:aff>
<country xml:lang="fr">Israël</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Friedman, Eitan" sort="Friedman, Eitan" uniqKey="Friedman E" first="Eitan" last="Friedman">Eitan Friedman</name>
<affiliation wicri:level="1"><nlm:aff id="af33"><addr-line>The Susanne Levy Gertner Oncogenetics Unit</addr-line>
,<institution>Sheba Medical Center</institution>
,<addr-line>Tel Hashomer</addr-line>
,<country>Israel</country>
,</nlm:aff>
<country xml:lang="fr">Israël</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Loman, Niklas" sort="Loman, Niklas" uniqKey="Loman N" first="Niklas" last="Loman">Niklas Loman</name>
<affiliation wicri:level="1"><nlm:aff id="af35"><addr-line>Department of Oncology</addr-line>
,<institution>Lund University Hospital</institution>
,<addr-line>Lund</addr-line>
,<country>Sweden</country>
,</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Harbst, Katja" sort="Harbst, Katja" uniqKey="Harbst K" first="Katja" last="Harbst">Katja Harbst</name>
<affiliation wicri:level="1"><nlm:aff id="af35"><addr-line>Department of Oncology</addr-line>
,<institution>Lund University Hospital</institution>
,<addr-line>Lund</addr-line>
,<country>Sweden</country>
,</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lindblom, Annika" sort="Lindblom, Annika" uniqKey="Lindblom A" first="Annika" last="Lindblom">Annika Lindblom</name>
<affiliation><nlm:aff wicri:cut=" and" id="af36"><addr-line>Department of Clinical Genetics</addr-line>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Arver, Brita" sort="Arver, Brita" uniqKey="Arver B" first="Brita" last="Arver">Brita Arver</name>
<affiliation wicri:level="1"><nlm:aff id="af37"><addr-line>Department of Oncology</addr-line>
,<institution>Karolinska University Hospital</institution>
,<addr-line>S-17176 Stockholm</addr-line>
,<country>Sweden</country>
,</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ehrencrona, Hans" sort="Ehrencrona, Hans" uniqKey="Ehrencrona H" first="Hans" last="Ehrencrona">Hans Ehrencrona</name>
<affiliation wicri:level="1"><nlm:aff id="af38"><addr-line>Department of Genetics and Pathology</addr-line>
,<institution>Rudbeck Laboratory, Uppsala University</institution>
,<addr-line>S-751 85 Uppsala</addr-line>
,<country>Sweden</country>
,</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Melin, Beatrice" sort="Melin, Beatrice" uniqKey="Melin B" first="Beatrice" last="Melin">Beatrice Melin</name>
<affiliation wicri:level="1"><nlm:aff id="af39"><addr-line>Department of Radiation Sciences</addr-line>
,<institution>Oncology, Umeå University</institution>
,<addr-line>S-901 85 Umeå</addr-line>
,<country>Sweden</country>
,</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Nathanson, Katherine L" sort="Nathanson, Katherine L" uniqKey="Nathanson K" first="Katherine L." last="Nathanson">Katherine L. Nathanson</name>
<affiliation wicri:level="1"><nlm:aff id="af40"><institution>University of Pennsylvania</institution>
,<addr-line>Philadelphia, PA</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Domchek, Susan M" sort="Domchek, Susan M" uniqKey="Domchek S" first="Susan M." last="Domchek">Susan M. Domchek</name>
<affiliation wicri:level="1"><nlm:aff id="af40"><institution>University of Pennsylvania</institution>
,<addr-line>Philadelphia, PA</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rebbeck, Timothy" sort="Rebbeck, Timothy" uniqKey="Rebbeck T" first="Timothy" last="Rebbeck">Timothy Rebbeck</name>
<affiliation wicri:level="1"><nlm:aff id="af40"><institution>University of Pennsylvania</institution>
,<addr-line>Philadelphia, PA</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Jakubowska, Ania" sort="Jakubowska, Ania" uniqKey="Jakubowska A" first="Ania" last="Jakubowska">Ania Jakubowska</name>
<affiliation wicri:level="1"><nlm:aff id="af41"><addr-line>International Hereditary Cancer Centre, Department of Genetics and Pathology</addr-line>
,<institution>Pomeranian Medical University</institution>
,<addr-line>Szczecin</addr-line>
,<country>Poland</country>
,</nlm:aff>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lubinski, Jan" sort="Lubinski, Jan" uniqKey="Lubinski J" first="Jan" last="Lubinski">Jan Lubinski</name>
<affiliation wicri:level="1"><nlm:aff id="af41"><addr-line>International Hereditary Cancer Centre, Department of Genetics and Pathology</addr-line>
,<institution>Pomeranian Medical University</institution>
,<addr-line>Szczecin</addr-line>
,<country>Poland</country>
,</nlm:aff>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gronwald, Jacek" sort="Gronwald, Jacek" uniqKey="Gronwald J" first="Jacek" last="Gronwald">Jacek Gronwald</name>
<affiliation wicri:level="1"><nlm:aff id="af41"><addr-line>International Hereditary Cancer Centre, Department of Genetics and Pathology</addr-line>
,<institution>Pomeranian Medical University</institution>
,<addr-line>Szczecin</addr-line>
,<country>Poland</country>
,</nlm:aff>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Huzarski, Tomasz" sort="Huzarski, Tomasz" uniqKey="Huzarski T" first="Tomasz" last="Huzarski">Tomasz Huzarski</name>
<affiliation wicri:level="1"><nlm:aff id="af41"><addr-line>International Hereditary Cancer Centre, Department of Genetics and Pathology</addr-line>
,<institution>Pomeranian Medical University</institution>
,<addr-line>Szczecin</addr-line>
,<country>Poland</country>
,</nlm:aff>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Byrski, Tomasz" sort="Byrski, Tomasz" uniqKey="Byrski T" first="Tomasz" last="Byrski">Tomasz Byrski</name>
<affiliation wicri:level="1"><nlm:aff id="af41"><addr-line>International Hereditary Cancer Centre, Department of Genetics and Pathology</addr-line>
,<institution>Pomeranian Medical University</institution>
,<addr-line>Szczecin</addr-line>
,<country>Poland</country>
,</nlm:aff>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Cybulski, Cezary" sort="Cybulski, Cezary" uniqKey="Cybulski C" first="Cezary" last="Cybulski">Cezary Cybulski</name>
<affiliation wicri:level="1"><nlm:aff id="af41"><addr-line>International Hereditary Cancer Centre, Department of Genetics and Pathology</addr-line>
,<institution>Pomeranian Medical University</institution>
,<addr-line>Szczecin</addr-line>
,<country>Poland</country>
,</nlm:aff>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gorski, Bohdan" sort="Gorski, Bohdan" uniqKey="Gorski B" first="Bohdan" last="Gorski">Bohdan Gorski</name>
<affiliation wicri:level="1"><nlm:aff id="af41"><addr-line>International Hereditary Cancer Centre, Department of Genetics and Pathology</addr-line>
,<institution>Pomeranian Medical University</institution>
,<addr-line>Szczecin</addr-line>
,<country>Poland</country>
,</nlm:aff>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Osorio, Ana" sort="Osorio, Ana" uniqKey="Osorio A" first="Ana" last="Osorio">Ana Osorio</name>
<affiliation wicri:level="1"><nlm:aff id="af42"><addr-line>Human Genetics Group, Human Cancer Genetics Programme</addr-line>
,<institution>Spanish National Cancer Research Centre</institution>
,<addr-line>Madrid</addr-line>
,<country>Spain</country>
,</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation><nlm:aff id="af43"><addr-line>Spanish Network on Rare Diseases (CIBERER)</addr-line>
,</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ram N Y Cajal, Teresa" sort="Ram N Y Cajal, Teresa" uniqKey="Ram N Y Cajal T" first="Teresa" last="Ram N Y Cajal">Teresa Ram N Y Cajal</name>
<affiliation wicri:level="1"><nlm:aff id="af44"><addr-line>Oncology Service</addr-line>
,<institution>Hospital de la Santa Creu i Sant Pau</institution>
,<addr-line>Barcelona</addr-line>
,<country>Spain</country>
,</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Fostira, Florentia" sort="Fostira, Florentia" uniqKey="Fostira F" first="Florentia" last="Fostira">Florentia Fostira</name>
<affiliation wicri:level="1"><nlm:aff id="af45"><addr-line>Molecular Diagnostics Laboratory</addr-line>
,<institution>I.R.R.P., National Center for Scientific Research ‘Demokritos’</institution>
,<addr-line>Athens</addr-line>
,<country>Greece</country>
,</nlm:aff>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Andres, Raquel" sort="Andres, Raquel" uniqKey="Andres R" first="Raquel" last="Andrés">Raquel Andrés</name>
<affiliation wicri:level="1"><nlm:aff id="af46"><addr-line>Oncology unit</addr-line>
,<institution>Hospital clinico Universitario "Lozano Blesa"</institution>
,<addr-line>Zaragoza</addr-line>
,<country>Spain</country>
,</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Benitez, Javier" sort="Benitez, Javier" uniqKey="Benitez J" first="Javier" last="Benitez">Javier Benitez</name>
<affiliation wicri:level="1"><nlm:aff id="af42"><addr-line>Human Genetics Group, Human Cancer Genetics Programme</addr-line>
,<institution>Spanish National Cancer Research Centre</institution>
,<addr-line>Madrid</addr-line>
,<country>Spain</country>
,</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation><nlm:aff id="af43"><addr-line>Spanish Network on Rare Diseases (CIBERER)</addr-line>
,</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hamann, Ute" sort="Hamann, Ute" uniqKey="Hamann U" first="Ute" last="Hamann">Ute Hamann</name>
<affiliation wicri:level="1"><nlm:aff id="af47"><addr-line>Molecular Genetics of Breast Cancer</addr-line>
,<institution>Deutsches Krebsforschungszentrum (DKFZ)</institution>
,<addr-line>Heidelberg</addr-line>
,<country>Germany</country>
,</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hogervorst, Frans B" sort="Hogervorst, Frans B" uniqKey="Hogervorst F" first="Frans B." last="Hogervorst">Frans B. Hogervorst</name>
<affiliation><nlm:aff wicri:cut=" and" id="af48"><addr-line>Family Cancer Clinic</addr-line>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rookus, Matti A" sort="Rookus, Matti A" uniqKey="Rookus M" first="Matti A." last="Rookus">Matti A. Rookus</name>
<affiliation wicri:level="1"><nlm:aff id="af49"><addr-line>Department of Epidemiology</addr-line>
,<institution>Netherlands Cancer Institute</institution>
,<addr-line>Amsterdam</addr-line>
,<country>The Netherlands</country>
,</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hooning, Maartje J" sort="Hooning, Maartje J" uniqKey="Hooning M" first="Maartje J." last="Hooning">Maartje J. Hooning</name>
<affiliation wicri:level="1"><nlm:aff id="af50"><addr-line>Department of Medical Oncology</addr-line>
,<institution>Family Cancer Clinic, Erasmus University Medical Center</institution>
,<addr-line>Rotterdam</addr-line>
,<country>The Netherlands</country>
,</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Nelen, Marcel R" sort="Nelen, Marcel R" uniqKey="Nelen M" first="Marcel R." last="Nelen">Marcel R. Nelen</name>
<affiliation wicri:level="1"><nlm:aff id="af51"><addr-line>Department of Human Genetics 849</addr-line>
,<institution>Radboud University Nijmegen Medical Centre</institution>
,<addr-line>Nijmegen</addr-line>
,<country>The Netherlands</country>
,</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Der Luijt, Rob B" sort="Van Der Luijt, Rob B" uniqKey="Van Der Luijt R" first="Rob B." last="Van Der Luijt">Rob B. Van Der Luijt</name>
<affiliation wicri:level="1"><nlm:aff id="af52"><addr-line>Department of Medical Genetics</addr-line>
,<institution>University Medical Center Utrecht</institution>
,<addr-line>Utrecht</addr-line>
,<country>The Netherlands</country>
,</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Os, Theo A M" sort="Van Os, Theo A M" uniqKey="Van Os T" first="Theo A. M." last="Van Os">Theo A. M. Van Os</name>
<affiliation wicri:level="1"><nlm:aff id="af53"><addr-line>Department of Clinical Genetics</addr-line>
,<institution>Academic Medical Center</institution>
,<addr-line>Amsterdam</addr-line>
,<country>The Netherlands</country>
,</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Asperen, Christi J" sort="Van Asperen, Christi J" uniqKey="Van Asperen C" first="Christi J." last="Van Asperen">Christi J. Van Asperen</name>
<affiliation><nlm:aff id="af54"><addr-line>Department of Clinical Genetics</addr-line>
,</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Devilee, Peter" sort="Devilee, Peter" uniqKey="Devilee P" first="Peter" last="Devilee">Peter Devilee</name>
<affiliation><nlm:aff wicri:cut=" and" id="af55"><addr-line>Department of Human Genetics</addr-line>
</nlm:aff>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af56"><addr-line>Department of Pathology</addr-line>
,<institution>Leiden University Medical Center Leiden</institution>
,<addr-line>Leiden</addr-line>
,<country>The Netherlands</country>
,</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Meijers Heijboer, Hanne E J" sort="Meijers Heijboer, Hanne E J" uniqKey="Meijers Heijboer H" first="Hanne E. J." last="Meijers-Heijboer">Hanne E. J. Meijers-Heijboer</name>
<affiliation wicri:level="1"><nlm:aff id="af57"><addr-line>Department of Clinical Genetics</addr-line>
,<institution>VU Medical Center</institution>
,<addr-line>Amsterdam</addr-line>
,<country>The Netherlands</country>
,</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="G Mez Garcia, Encarna B" sort="G Mez Garcia, Encarna B" uniqKey="G Mez Garcia E" first="Encarna B." last="G Mez Garcia">Encarna B. G Mez Garcia</name>
<affiliation><nlm:aff wicri:cut=" and" id="af58"><addr-line>Department of Clinical Genetics and GROM, School for Oncology</addr-line>
</nlm:aff>
<wicri:noCountry code="subfield">School for Oncology</wicri:noCountry>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af59"><addr-line>Developmental Biology</addr-line>
,<institution>MUMC</institution>
,<addr-line>Maastricht</addr-line>
,<country>The Netherlands</country>
,</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Peock, Susan" sort="Peock, Susan" uniqKey="Peock S" first="Susan" last="Peock">Susan Peock</name>
<affiliation><nlm:aff wicri:cut=" and" id="af1"><addr-line>Department of Public Health and Primary Care</addr-line>
,<institution>Centre for Cancer Genetic Epidemiology</institution>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Cook, Margaret" sort="Cook, Margaret" uniqKey="Cook M" first="Margaret" last="Cook">Margaret Cook</name>
<affiliation><nlm:aff wicri:cut=" and" id="af1"><addr-line>Department of Public Health and Primary Care</addr-line>
,<institution>Centre for Cancer Genetic Epidemiology</institution>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Frost, Debra" sort="Frost, Debra" uniqKey="Frost D" first="Debra" last="Frost">Debra Frost</name>
<affiliation><nlm:aff wicri:cut=" and" id="af1"><addr-line>Department of Public Health and Primary Care</addr-line>
,<institution>Centre for Cancer Genetic Epidemiology</institution>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Platte, Radka" sort="Platte, Radka" uniqKey="Platte R" first="Radka" last="Platte">Radka Platte</name>
<affiliation><nlm:aff wicri:cut=" and" id="af1"><addr-line>Department of Public Health and Primary Care</addr-line>
,<institution>Centre for Cancer Genetic Epidemiology</institution>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Leyland, Jean" sort="Leyland, Jean" uniqKey="Leyland J" first="Jean" last="Leyland">Jean Leyland</name>
<affiliation><nlm:aff wicri:cut=" and" id="af1"><addr-line>Department of Public Health and Primary Care</addr-line>
,<institution>Centre for Cancer Genetic Epidemiology</institution>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Gareth Evans, D" sort="Gareth Evans, D" uniqKey="Gareth Evans D" first="D." last="Gareth Evans">D. Gareth Evans</name>
<affiliation wicri:level="1"><nlm:aff id="af60"><addr-line>Genetic Medicine</addr-line>
,<institution>Manchester Academic Health Sciences Centre, Central Manchester University Hospitals NHS Foundation Trust</institution>
,<addr-line>Manchester</addr-line>
,<country>UK</country>
,</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lalloo, Fiona" sort="Lalloo, Fiona" uniqKey="Lalloo F" first="Fiona" last="Lalloo">Fiona Lalloo</name>
<affiliation wicri:level="1"><nlm:aff id="af60"><addr-line>Genetic Medicine</addr-line>
,<institution>Manchester Academic Health Sciences Centre, Central Manchester University Hospitals NHS Foundation Trust</institution>
,<addr-line>Manchester</addr-line>
,<country>UK</country>
,</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Eeles, Ros" sort="Eeles, Ros" uniqKey="Eeles R" first="Ros" last="Eeles">Ros Eeles</name>
<affiliation wicri:level="1"><nlm:aff id="af61"><addr-line>Oncogenetics Team</addr-line>
,<institution>The Institute of Cancer Research and Royal Marsden NHS Foundation Trust</institution>
,<addr-line>Surrey</addr-line>
,<country>UK</country>
,</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Izatt, Louise" sort="Izatt, Louise" uniqKey="Izatt L" first="Louise" last="Izatt">Louise Izatt</name>
<affiliation wicri:level="1"><nlm:aff id="af62"><addr-line>Clinical Genetics</addr-line>
,<institution>Guy's and St. Thomas’ NHS Foundation Trust</institution>
,<addr-line>London</addr-line>
,<country>UK</country>
,</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Adlard, Julian" sort="Adlard, Julian" uniqKey="Adlard J" first="Julian" last="Adlard">Julian Adlard</name>
<affiliation wicri:level="1"><nlm:aff id="af63"><institution>Yorkshire Regional Genetics Service</institution>
,<addr-line>Leeds</addr-line>
,<country>UK</country>
,</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Davidson, Rosemarie" sort="Davidson, Rosemarie" uniqKey="Davidson R" first="Rosemarie" last="Davidson">Rosemarie Davidson</name>
<affiliation wicri:level="1"><nlm:aff id="af64"><addr-line>Ferguson-Smith Centre for Clinical Genetics</addr-line>
,<institution>Yorkhill Hospitals</institution>
,<addr-line>Glasgow</addr-line>
,<country>UK</country>
,</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Eccles, Diana" sort="Eccles, Diana" uniqKey="Eccles D" first="Diana" last="Eccles">Diana Eccles</name>
<affiliation wicri:level="1"><nlm:aff id="af65"><addr-line>Wessex Clinical Genetics Service</addr-line>
<institution>, Princess Anne Hospital</institution>
,<addr-line>Southampton</addr-line>
,<country>UK</country>
,</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ong, Kai Ren" sort="Ong, Kai Ren" uniqKey="Ong K" first="Kai-Ren" last="Ong">Kai-Ren Ong</name>
<affiliation wicri:level="1"><nlm:aff id="af66"><addr-line>West Midlands Regional Genetics Service</addr-line>
,<institution>Birmingham Women's Hospital Healthcare NHS Trust</institution>
,<addr-line>Edgbaston, Birmingham</addr-line>
,<country>UK</country>
,</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Cook, Jackie" sort="Cook, Jackie" uniqKey="Cook J" first="Jackie" last="Cook">Jackie Cook</name>
<affiliation wicri:level="1"><nlm:aff id="af67"><addr-line>Sheffield Clinical Genetics Service</addr-line>
,<institution>Sheffield Children's Hospital</institution>
,<addr-line>Sheffield</addr-line>
,<country>UK</country>
,</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Douglas, Fiona" sort="Douglas, Fiona" uniqKey="Douglas F" first="Fiona" last="Douglas">Fiona Douglas</name>
<affiliation wicri:level="1"><nlm:aff id="af68"><institution>Institute of Human Genetics, Centre for Life, Newcastle Upon Tyne Hospitals NHS Trust</institution>
,<addr-line>Newcastle upon Tyne</addr-line>
,<country>UK</country>
,</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Paterson, Joan" sort="Paterson, Joan" uniqKey="Paterson J" first="Joan" last="Paterson">Joan Paterson</name>
<affiliation wicri:level="1"><nlm:aff id="af69"><addr-line>Department of Clinical Genetics, East Anglian Regional Genetics Service</addr-line>
,<institution>Addenbrookes Hospital</institution>
,<addr-line>Cambridge</addr-line>
,<country>UK</country>
,</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="John Kennedy, M" sort="John Kennedy, M" uniqKey="John Kennedy M" first="M." last="John Kennedy">M. John Kennedy</name>
<affiliation><nlm:aff id="af70"><addr-line>Academic Unit of Clinical and Molecular Oncology</addr-line>
,<institution>Trinity College Dublin and St James's Hospital</institution>
,<addr-line>Dublin</addr-line>
,<country>Eire</country>
,</nlm:aff>
<wicri:noCountry code="nlm country">Eire</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Miedzybrodzka, Zosia" sort="Miedzybrodzka, Zosia" uniqKey="Miedzybrodzka Z" first="Zosia" last="Miedzybrodzka">Zosia Miedzybrodzka</name>
<affiliation wicri:level="1"><nlm:aff id="af71"><addr-line>North of Scotland Regional Genetics Service</addr-line>
,<institution>NHS Grampian & University of Aberdeen</institution>
,<addr-line>Foresterhill, Aberdeen</addr-line>
,<country>UK</country>
,</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Godwin, Andrew" sort="Godwin, Andrew" uniqKey="Godwin A" first="Andrew" last="Godwin">Andrew Godwin</name>
<affiliation wicri:level="1"><nlm:aff id="af72"><addr-line>Department of Pathology and Laboratory Medicine</addr-line>
,<institution>University of Kansas Medical Center</institution>
,<addr-line>Kansas City</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Stoppa Lyonnet, Dominique" sort="Stoppa Lyonnet, Dominique" uniqKey="Stoppa Lyonnet D" first="Dominique" last="Stoppa-Lyonnet">Dominique Stoppa-Lyonnet</name>
<affiliation><nlm:aff wicri:cut=" and" id="af73"><addr-line>Service de Génétique Oncologique</addr-line>
</nlm:aff>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af74"><addr-line>Unité INSERM U830</addr-line>
,<institution>Institut Curie</institution>
,<addr-line>Paris</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af75"><addr-line>Faculté de Médecine</addr-line>
,<institution>Université Paris Descartes</institution>
,<addr-line>Paris</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Buecher, Bruno" sort="Buecher, Bruno" uniqKey="Buecher B" first="Bruno" last="Buecher">Bruno Buecher</name>
<affiliation><nlm:aff wicri:cut=" and" id="af73"><addr-line>Service de Génétique Oncologique</addr-line>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Belotti, Muriel" sort="Belotti, Muriel" uniqKey="Belotti M" first="Muriel" last="Belotti">Muriel Belotti</name>
<affiliation><nlm:aff wicri:cut=" and" id="af73"><addr-line>Service de Génétique Oncologique</addr-line>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Tirapo, Carole" sort="Tirapo, Carole" uniqKey="Tirapo C" first="Carole" last="Tirapo">Carole Tirapo</name>
<affiliation><nlm:aff wicri:cut=" and" id="af73"><addr-line>Service de Génétique Oncologique</addr-line>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Mazoyer, Sylvie" sort="Mazoyer, Sylvie" uniqKey="Mazoyer S" first="Sylvie" last="Mazoyer">Sylvie Mazoyer</name>
<affiliation wicri:level="1"><nlm:aff id="af4"><addr-line>Equipe labellisée LIGUE 2008, UMR5201 CNRS, Centre Léon Bérard</addr-line>
,<institution>Université de Lyon</institution>
,<addr-line>Lyon</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Barjhoux, Laure" sort="Barjhoux, Laure" uniqKey="Barjhoux L" first="Laure" last="Barjhoux">Laure Barjhoux</name>
<affiliation wicri:level="1"><nlm:aff id="af4"><addr-line>Equipe labellisée LIGUE 2008, UMR5201 CNRS, Centre Léon Bérard</addr-line>
,<institution>Université de Lyon</institution>
,<addr-line>Lyon</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lasset, Christine" sort="Lasset, Christine" uniqKey="Lasset C" first="Christine" last="Lasset">Christine Lasset</name>
<affiliation wicri:level="1"><nlm:aff id="af76"><addr-line>CNRS UMR5558</addr-line>
,<institution>Université Lyon 1</institution>
,<addr-line>Lyon</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af77"><addr-line>Unité de Prévention et d'Epidémiologie Génétique</addr-line>
,<institution>Centre Léon Bérard</institution>
,<addr-line>Lyon</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Leroux, Dominique" sort="Leroux, Dominique" uniqKey="Leroux D" first="Dominique" last="Leroux">Dominique Leroux</name>
<affiliation wicri:level="1"><nlm:aff id="af78"><addr-line>Department of Genetics</addr-line>
,<institution>Centre Hospitalier Universitaire de Grenoble</institution>
,<addr-line>Grenoble</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af79"><institution>Institut Albert Bonniot, Université de Grenoble</institution>
,<addr-line>Grenoble</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Faivre, Laurence" sort="Faivre, Laurence" uniqKey="Faivre L" first="Laurence" last="Faivre">Laurence Faivre</name>
<affiliation wicri:level="1"><nlm:aff id="af80"><addr-line>Centre de Génétique</addr-line>
,<institution>Centre Hospitalier Universitaire de Dijon</institution>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af81"><institution>Centre de Lutte Contre le Cancer Georges François Leclerc</institution>
,<addr-line>Dijon</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bronner, Myriam" sort="Bronner, Myriam" uniqKey="Bronner M" first="Myriam" last="Bronner">Myriam Bronner</name>
<affiliation wicri:level="1"><nlm:aff id="af82"><addr-line>Laboratoire de Génétique Médicale</addr-line>
,<institution>Nancy Université, Centre Hospitalier Régional et Universitaire</institution>
,<addr-line>Vandoeuvre-les-Nancy</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Prieur, Fabienne" sort="Prieur, Fabienne" uniqKey="Prieur F" first="Fabienne" last="Prieur">Fabienne Prieur</name>
<affiliation wicri:level="1"><nlm:aff id="af83"><addr-line>Service de Génétique Clinique Chromosomique et Moléculaire</addr-line>
,<institution>Centre Hospitalier Universitaire de St Etienne</institution>
,<addr-line>St Etienne</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Nogues, Catherine" sort="Nogues, Catherine" uniqKey="Nogues C" first="Catherine" last="Nogues">Catherine Nogues</name>
<affiliation><nlm:aff wicri:cut=" and" id="af84"><addr-line>Oncogénétique Clinique</addr-line>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rouleau, Etienne" sort="Rouleau, Etienne" uniqKey="Rouleau E" first="Etienne" last="Rouleau">Etienne Rouleau</name>
<affiliation wicri:level="1"><nlm:aff id="af85"><addr-line>Laboratoire d'Oncogénétique</addr-line>
,<institution>Hôpital René Huguenin/Institut Curie</institution>
,<addr-line>Saint-Cloud</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pujol, Pascal" sort="Pujol, Pascal" uniqKey="Pujol P" first="Pascal" last="Pujol">Pascal Pujol</name>
<affiliation wicri:level="1"><nlm:aff id="af86"><addr-line>Unité d'Oncogénétique</addr-line>
,<institution>CHU Arnaud de Villeneuve</institution>
,<addr-line>Montpellier</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af87"><addr-line>INSERM 896</addr-line>
,<institution>CRCM Val d'Aurelle</institution>
,<addr-line>Montpellier</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Coupier, Isabelle" sort="Coupier, Isabelle" uniqKey="Coupier I" first="Isabelle" last="Coupier">Isabelle Coupier</name>
<affiliation wicri:level="1"><nlm:aff id="af86"><addr-line>Unité d'Oncogénétique</addr-line>
,<institution>CHU Arnaud de Villeneuve</institution>
,<addr-line>Montpellier</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af88"><addr-line>Unité d'Oncogénétique</addr-line>
,<institution>CRLCC Val d'Aurelle</institution>
,<addr-line>Montpellier</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Frenay, Marc" sort="Frenay, Marc" uniqKey="Frenay M" first="Marc" last="Frénay">Marc Frénay</name>
<affiliation wicri:level="1"><nlm:aff id="af89"><institution>Centre Antoine Lacassagne</institution>
,<addr-line>Nice</addr-line>
,<country>France</country>
,</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hopper, John L" sort="Hopper, John L" uniqKey="Hopper J" first="John L." last="Hopper">John L. Hopper</name>
<affiliation wicri:level="1"><nlm:aff id="af90"><institution>The University of Melbourne</institution>
,<addr-line>Melbourne</addr-line>
,<country>Australia</country>
,</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Daly, Mary B" sort="Daly, Mary B" uniqKey="Daly M" first="Mary B." last="Daly">Mary B. Daly</name>
<affiliation wicri:level="1"><nlm:aff id="af91"><addr-line>Women's Cancer Program, Department of Medical Oncology</addr-line>
,<institution>Fox Chase Cancer Center</institution>
,<addr-line>Philadelphia, PA</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Terry, Mary B" sort="Terry, Mary B" uniqKey="Terry M" first="Mary B." last="Terry">Mary B. Terry</name>
<affiliation wicri:level="1"><nlm:aff id="af92"><institution>Columbia University New York</institution>
,<addr-line>New York, NY</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="John, Esther M" sort="John, Esther M" uniqKey="John E" first="Esther M." last="John">Esther M. John</name>
<affiliation wicri:level="1"><nlm:aff id="af93"><institution>Cancer Prevention Institute of California (formerly the Northern California Cancer Center)</institution>
,<addr-line>Fremont, CA</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af94"><addr-line>Stanford Cancer Center</addr-line>
,<institution>Stanford University School of Medicine</institution>
,<addr-line>Stanford, CA</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Buys, Saundra S" sort="Buys, Saundra S" uniqKey="Buys S" first="Saundra S." last="Buys">Saundra S. Buys</name>
<affiliation wicri:level="1"><nlm:aff id="af95"><addr-line>Huntsman Cancer Institute</addr-line>
,<institution>University of Utah Health Sciences Centre</institution>
,<addr-line>Salt Lake City, UT</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Yassin, Yosuf" sort="Yassin, Yosuf" uniqKey="Yassin Y" first="Yosuf" last="Yassin">Yosuf Yassin</name>
<affiliation wicri:level="1"><nlm:aff id="af96"><institution>Dana-Farber Cancer Institute</institution>
,<addr-line>Boston, MA</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Miron, Alexander" sort="Miron, Alexander" uniqKey="Miron A" first="Alexander" last="Miron">Alexander Miron</name>
<affiliation wicri:level="1"><nlm:aff id="af96"><institution>Dana-Farber Cancer Institute</institution>
,<addr-line>Boston, MA</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Goldgar, David" sort="Goldgar, David" uniqKey="Goldgar D" first="David" last="Goldgar">David Goldgar</name>
<affiliation wicri:level="1"><nlm:aff id="af97"><addr-line>Department of Dermatology</addr-line>
,<institution>University of Utah</institution>
,<addr-line>Salt Lake City, UT</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Singer, Christian F" sort="Singer, Christian F" uniqKey="Singer C" first="Christian F." last="Singer">Christian F. Singer</name>
<affiliation wicri:level="1"><nlm:aff id="af98"><addr-line>Department of Obstetrics/Gynaecology</addr-line>
,<institution>Medical University of Vienna</institution>
,<addr-line>Vienna</addr-line>
,<country>Austria</country>
,</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tea, Muy Kheng" sort="Tea, Muy Kheng" uniqKey="Tea M" first="Muy-Kheng" last="Tea">Muy-Kheng Tea</name>
<affiliation wicri:level="1"><nlm:aff id="af98"><addr-line>Department of Obstetrics/Gynaecology</addr-line>
,<institution>Medical University of Vienna</institution>
,<addr-line>Vienna</addr-line>
,<country>Austria</country>
,</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pfeiler, Georg" sort="Pfeiler, Georg" uniqKey="Pfeiler G" first="Georg" last="Pfeiler">Georg Pfeiler</name>
<affiliation wicri:level="1"><nlm:aff id="af98"><addr-line>Department of Obstetrics/Gynaecology</addr-line>
,<institution>Medical University of Vienna</institution>
,<addr-line>Vienna</addr-line>
,<country>Austria</country>
,</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Catharina Dressler, Anne" sort="Catharina Dressler, Anne" uniqKey="Catharina Dressler A" first="Anne" last="Catharina Dressler">Anne Catharina Dressler</name>
<affiliation wicri:level="1"><nlm:aff id="af98"><addr-line>Department of Obstetrics/Gynaecology</addr-line>
,<institution>Medical University of Vienna</institution>
,<addr-line>Vienna</addr-line>
,<country>Austria</country>
,</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hansen, Thomas V O" sort="Hansen, Thomas V O" uniqKey="Hansen T" first="Thomas V. O." last="Hansen">Thomas V. O. Hansen</name>
<affiliation><nlm:aff wicri:cut=" and" id="af99"><addr-line>Genomic Medicine, Department of Clinical Biochemistry</addr-line>
</nlm:aff>
<wicri:noCountry code="subfield">Department of Clinical Biochemistry</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="J Nson, Lars" sort="J Nson, Lars" uniqKey="J Nson L" first="Lars" last="J Nson">Lars J Nson</name>
<affiliation><nlm:aff wicri:cut=" and" id="af99"><addr-line>Genomic Medicine, Department of Clinical Biochemistry</addr-line>
</nlm:aff>
<wicri:noCountry code="subfield">Department of Clinical Biochemistry</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Ejlertsen, Bent" sort="Ejlertsen, Bent" uniqKey="Ejlertsen B" first="Bent" last="Ejlertsen">Bent Ejlertsen</name>
<affiliation wicri:level="1"><nlm:aff id="af100"><addr-line>Department of Oncology</addr-line>
,<institution>Rigshospitalet</institution>
,<institution>Copenhagen University Hospital</institution>
,<addr-line>Allerød</addr-line>
,<country>Denmark</country>
,</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bjork Barkardottir, Rosa" sort="Bjork Barkardottir, Rosa" uniqKey="Bjork Barkardottir R" first="Rosa" last="Bjork Barkardottir">Rosa Bjork Barkardottir</name>
<affiliation wicri:level="1"><nlm:aff id="af101"><addr-line>Laboratory of Cell Biology, Department of Pathology</addr-line>
,<institution>Landspitali-University Hospital</institution>
,<addr-line>Tromsø</addr-line>
,<country>Norway,</country>
</nlm:aff>
<wicri:regionArea># see nlm:aff region in country</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af102"><addr-line>Faculty of Medicine</addr-line>
,<institution>University of Iceland</institution>
,<addr-line>Reykjavik</addr-line>
,<country>Iceland</country>
,</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kirchhoff, Tomas" sort="Kirchhoff, Tomas" uniqKey="Kirchhoff T" first="Tomas" last="Kirchhoff">Tomas Kirchhoff</name>
<affiliation wicri:level="1"><nlm:aff id="af103"><addr-line>Clinical Genetics Service, Department of Medicine</addr-line>
,<institution>Memorial Sloan-Kettering Cancer Center</institution>
,<addr-line>New York, NY</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Offit, Kenneth" sort="Offit, Kenneth" uniqKey="Offit K" first="Kenneth" last="Offit">Kenneth Offit</name>
<affiliation wicri:level="1"><nlm:aff id="af103"><addr-line>Clinical Genetics Service, Department of Medicine</addr-line>
,<institution>Memorial Sloan-Kettering Cancer Center</institution>
,<addr-line>New York, NY</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Piedmonte, Marion" sort="Piedmonte, Marion" uniqKey="Piedmonte M" first="Marion" last="Piedmonte">Marion Piedmonte</name>
<affiliation><nlm:aff wicri:cut=" and" id="af104"><addr-line>GOG Statistical and Data Center</addr-line>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rodriguez, Gustavo" sort="Rodriguez, Gustavo" uniqKey="Rodriguez G" first="Gustavo" last="Rodriguez">Gustavo Rodriguez</name>
<affiliation wicri:level="1"><nlm:aff id="af106"><institution>Evanston Northwestern Healthcare</institution>
,<addr-line>Evanston, IL</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Small, Laurie" sort="Small, Laurie" uniqKey="Small L" first="Laurie" last="Small">Laurie Small</name>
<affiliation wicri:level="1"><nlm:aff id="af107"><institution>Maine Medical Center</institution>
,<addr-line>Scarborough, ME</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Boggess, John" sort="Boggess, John" uniqKey="Boggess J" first="John" last="Boggess">John Boggess</name>
<affiliation wicri:level="1"><nlm:aff id="af108"><institution>University of North Carolina</institution>
,<addr-line>Chapel Hill, NC</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Blank, Stephanie" sort="Blank, Stephanie" uniqKey="Blank S" first="Stephanie" last="Blank">Stephanie Blank</name>
<affiliation wicri:level="1"><nlm:aff id="af109"><institution>New York University School of Medicine</institution>
,<addr-line>New York, NY</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Basil, Jack" sort="Basil, Jack" uniqKey="Basil J" first="Jack" last="Basil">Jack Basil</name>
<affiliation wicri:level="1"><nlm:aff id="af110"><institution>St. Elizabeth Medical Center</institution>
,<addr-line>Edgewood, KY</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Azodi, Masoud" sort="Azodi, Masoud" uniqKey="Azodi M" first="Masoud" last="Azodi">Masoud Azodi</name>
<affiliation wicri:level="1"><nlm:aff id="af111"><institution>Yale University School of Medicine</institution>
,<addr-line>New Haven, CT</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ewart Toland, Amanda" sort="Ewart Toland, Amanda" uniqKey="Ewart Toland A" first="Amanda" last="Ewart Toland">Amanda Ewart Toland</name>
<affiliation wicri:level="1"><nlm:aff id="af112"><addr-line>Comprehensive Cancer Center, Department of Molecular Virology, Immunology and Medical Genetics</addr-line>
,<institution>The Ohio State University</institution>
,<addr-line>Columbus, OH</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Montagna, Marco" sort="Montagna, Marco" uniqKey="Montagna M" first="Marco" last="Montagna">Marco Montagna</name>
<affiliation wicri:level="1"><nlm:aff id="af113"><addr-line>Immunology and Molecular Oncology Unit</addr-line>
,<institution>Istituto Oncologico Veneto IOV - IRCCS</institution>
,<addr-line>Padua</addr-line>
,<country>Italy</country>
,</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tognazzo, Silvia" sort="Tognazzo, Silvia" uniqKey="Tognazzo S" first="Silvia" last="Tognazzo">Silvia Tognazzo</name>
<affiliation wicri:level="1"><nlm:aff id="af113"><addr-line>Immunology and Molecular Oncology Unit</addr-line>
,<institution>Istituto Oncologico Veneto IOV - IRCCS</institution>
,<addr-line>Padua</addr-line>
,<country>Italy</country>
,</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Agata, Simona" sort="Agata, Simona" uniqKey="Agata S" first="Simona" last="Agata">Simona Agata</name>
<affiliation wicri:level="1"><nlm:aff id="af113"><addr-line>Immunology and Molecular Oncology Unit</addr-line>
,<institution>Istituto Oncologico Veneto IOV - IRCCS</institution>
,<addr-line>Padua</addr-line>
,<country>Italy</country>
,</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Imyanitov, Evgeny" sort="Imyanitov, Evgeny" uniqKey="Imyanitov E" first="Evgeny" last="Imyanitov">Evgeny Imyanitov</name>
<affiliation wicri:level="1"><nlm:aff id="af114"><institution>N.N. Petrov Institute of Oncology</institution>
,<addr-line>St.-Petersburg</addr-line>
, 197758,<country>Russia</country>
,</nlm:aff>
<country xml:lang="fr">Russie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Janavicius, Ramunas" sort="Janavicius, Ramunas" uniqKey="Janavicius R" first="Ramunas" last="Janavicius">Ramunas Janavicius</name>
<affiliation wicri:level="1"><nlm:aff id="af115"><addr-line>Department of Molecular and Regenerative Medicine</addr-line>
,<institution>Vilnius university hospital Santariskiu Clinics</institution>
,<institution>Hematology</institution>
,<institution>Oncology and Transfusion Medicine Center</institution>
,<addr-line>Vilnius</addr-line>
,<country>Lithuania</country>
,</nlm:aff>
<country xml:lang="fr">Lituanie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af116"><institution>State Research Institute Inovative medicine center</institution>
,<addr-line>Vilnius</addr-line>
,<country>Lithuania</country>
,</nlm:aff>
<country xml:lang="fr">Lituanie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lazaro, Conxi" sort="Lazaro, Conxi" uniqKey="Lazaro C" first="Conxi" last="Lazaro">Conxi Lazaro</name>
<affiliation wicri:level="1"><nlm:aff id="af117"><addr-line>Hereditary Cancer Program</addr-line>
,<institution>Catalan Institute of Oncology</institution>
,<addr-line>Barcelona</addr-line>
,<country>Spain</country>
,</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Blanco, Ignacio" sort="Blanco, Ignacio" uniqKey="Blanco I" first="Ignacio" last="Blanco">Ignacio Blanco</name>
<affiliation wicri:level="1"><nlm:aff id="af117"><addr-line>Hereditary Cancer Program</addr-line>
,<institution>Catalan Institute of Oncology</institution>
,<addr-line>Barcelona</addr-line>
,<country>Spain</country>
,</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pharoah, Paul D P" sort="Pharoah, Paul D P" uniqKey="Pharoah P" first="Paul D. P." last="Pharoah">Paul D. P. Pharoah</name>
<affiliation wicri:level="1"><nlm:aff id="af2"><addr-line>Department of Oncology</addr-line>
,<institution>University of Cambridge</institution>
,<addr-line>Cambridge</addr-line>
,<country>UK</country>
,</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sucheston, Lara" sort="Sucheston, Lara" uniqKey="Sucheston L" first="Lara" last="Sucheston">Lara Sucheston</name>
<affiliation wicri:level="1"><nlm:aff id="af105"><addr-line>Department of Cancer Prevention and Control</addr-line>
,<institution>Roswell Park Cancer Institute</institution>
,<addr-line>Buffalo, NY</addr-line>
14263,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Karlan, Beth Y" sort="Karlan, Beth Y" uniqKey="Karlan B" first="Beth Y." last="Karlan">Beth Y. Karlan</name>
<affiliation wicri:level="1"><nlm:aff id="af118"><institution>Women's Cancer Research Institute at the Samuel Oschin Comprehensive Cancer Institute</institution>
,<institution>Cedars-Sinai Medical Center</institution>
,<addr-line>Los Angeles, CA</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Walsh, Christine S" sort="Walsh, Christine S" uniqKey="Walsh C" first="Christine S." last="Walsh">Christine S. Walsh</name>
<affiliation wicri:level="1"><nlm:aff id="af118"><institution>Women's Cancer Research Institute at the Samuel Oschin Comprehensive Cancer Institute</institution>
,<institution>Cedars-Sinai Medical Center</institution>
,<addr-line>Los Angeles, CA</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Olah, Edith" sort="Olah, Edith" uniqKey="Olah E" first="Edith" last="Olah">Edith Olah</name>
<affiliation wicri:level="1"><nlm:aff id="af119"><addr-line>Department of Molecular Genetics</addr-line>
,<institution>National Institute of Oncology</institution>
,<addr-line>Budapest</addr-line>
,<country>Hungary</country>
,</nlm:aff>
<country xml:lang="fr">Hongrie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bozsik, Aniko" sort="Bozsik, Aniko" uniqKey="Bozsik A" first="Aniko" last="Bozsik">Aniko Bozsik</name>
<affiliation wicri:level="1"><nlm:aff id="af119"><addr-line>Department of Molecular Genetics</addr-line>
,<institution>National Institute of Oncology</institution>
,<addr-line>Budapest</addr-line>
,<country>Hungary</country>
,</nlm:aff>
<country xml:lang="fr">Hongrie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Teo, Soo Hwang" sort="Teo, Soo Hwang" uniqKey="Teo S" first="Soo-Hwang" last="Teo">Soo-Hwang Teo</name>
<affiliation wicri:level="1"><nlm:aff id="af120"><addr-line>Cancer Research Initiatives Foundation</addr-line>
,<institution>Sime Darby Medical Centre</institution>
,<addr-line>Subang Jaya</addr-line>
,<country>Malaysia</country>
,</nlm:aff>
<country xml:lang="fr">Malaisie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af121"><institution>University Malaya Cancer Research Institute</institution>
,<institution>University Malaya</institution>
,<addr-line>Kuala Lumpur</addr-line>
,<country>Malaysia</country>
,</nlm:aff>
<country xml:lang="fr">Malaisie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Seldon, Joyce L" sort="Seldon, Joyce L" uniqKey="Seldon J" first="Joyce L." last="Seldon">Joyce L. Seldon</name>
<affiliation wicri:level="1"><nlm:aff id="af122"><addr-line>UCLA Cancer Genetics Program</addr-line>
,<institution>CLA Jonsson Comp Cancer Center</institution>
,<addr-line>Santa Monica, CA</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Beattie, Mary S" sort="Beattie, Mary S" uniqKey="Beattie M" first="Mary S." last="Beattie">Mary S. Beattie</name>
<affiliation wicri:level="1"><nlm:aff id="af123"><addr-line>UCSF Cancer Risk Program</addr-line>
,<institution>University of California</institution>
,<addr-line>San Francisco, CA</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation><nlm:aff id="af124"><addr-line>UCSF Department of Medicine</addr-line>
,</nlm:aff>
</affiliation>
<affiliation><nlm:aff wicri:cut=" and" id="af125"><addr-line>Department of Epidemiology</addr-line>
</nlm:aff>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af126"><addr-line>Department of Biostatistics</addr-line>
,<institution>University of California</institution>
,<addr-line>San Francisco, CA</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Rensburg, Elizabeth J" sort="Van Rensburg, Elizabeth J" uniqKey="Van Rensburg E" first="Elizabeth J." last="Van Rensburg">Elizabeth J. Van Rensburg</name>
<affiliation wicri:level="1"><nlm:aff id="af127"><addr-line>Department of Genetics</addr-line>
,<institution>University of Pretoria</institution>
,<addr-line>Pretoria</addr-line>
,<country>South Africa</country>
,</nlm:aff>
<country xml:lang="fr">Afrique du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sluiter, Michelle D" sort="Sluiter, Michelle D" uniqKey="Sluiter M" first="Michelle D." last="Sluiter">Michelle D. Sluiter</name>
<affiliation wicri:level="1"><nlm:aff id="af127"><addr-line>Department of Genetics</addr-line>
,<institution>University of Pretoria</institution>
,<addr-line>Pretoria</addr-line>
,<country>South Africa</country>
,</nlm:aff>
<country xml:lang="fr">Afrique du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Diez, Orland" sort="Diez, Orland" uniqKey="Diez O" first="Orland" last="Diez">Orland Diez</name>
<affiliation wicri:level="1"><nlm:aff id="af128"><addr-line>Oncogenetics Laboratory</addr-line>
,<institution>University Hospital Vall d'Hebron</institution>
,<addr-line>Barcelona</addr-line>
,<country>Spain</country>
,</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af129"><institution>Vall d'Hebron Institute of Oncology (VHIO)</institution>
,<addr-line>Barcelona</addr-line>
,<country>Spain</country>
,</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schmutzler, Rita K" sort="Schmutzler, Rita K" uniqKey="Schmutzler R" first="Rita K." last="Schmutzler">Rita K. Schmutzler</name>
<affiliation><nlm:aff wicri:cut=" and" id="af130"><addr-line>Centre of Familial Breast and Ovarian Cancer, Department of Gynaecology and Obstetrics</addr-line>
</nlm:aff>
<wicri:noCountry code="subfield">Department of Gynaecology and Obstetrics</wicri:noCountry>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af131"><addr-line>Centre for Integrated Oncology (CIO)</addr-line>
,<institution>University hospital of Cologne</institution>
,<addr-line>Cologne</addr-line>
,<country>Germany</country>
,</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wappenschmidt, Barbara" sort="Wappenschmidt, Barbara" uniqKey="Wappenschmidt B" first="Barbara" last="Wappenschmidt">Barbara Wappenschmidt</name>
<affiliation><nlm:aff wicri:cut=" and" id="af130"><addr-line>Centre of Familial Breast and Ovarian Cancer, Department of Gynaecology and Obstetrics</addr-line>
</nlm:aff>
<wicri:noCountry code="subfield">Department of Gynaecology and Obstetrics</wicri:noCountry>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af131"><addr-line>Centre for Integrated Oncology (CIO)</addr-line>
,<institution>University hospital of Cologne</institution>
,<addr-line>Cologne</addr-line>
,<country>Germany</country>
,</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Engel, Christoph" sort="Engel, Christoph" uniqKey="Engel C" first="Christoph" last="Engel">Christoph Engel</name>
<affiliation wicri:level="1"><nlm:aff id="af132"><addr-line>Institute for Medical Informatics, Statistics and Epidemiology</addr-line>
,<institution>University of Leipzig</institution>
,<addr-line>Leipzig</addr-line>
,<country>Germany</country>
,</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Meindl, Alfons" sort="Meindl, Alfons" uniqKey="Meindl A" first="Alfons" last="Meindl">Alfons Meindl</name>
<affiliation wicri:level="1"><nlm:aff id="af133"><addr-line>Department of Gynaecology and Obstetrics, Division of Tumor Genetics, Klinikum rechts der Isar</addr-line>
,<institution>Technical University Munich</institution>
,<addr-line>Munich</addr-line>
,<country>Germany</country>
,</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ruehl, Ina" sort="Ruehl, Ina" uniqKey="Ruehl I" first="Ina" last="Ruehl">Ina Ruehl</name>
<affiliation wicri:level="1"><nlm:aff id="af134"><addr-line>Department of Gynaecology and Obstetrics</addr-line>
,<institution>Ludwig-Maximillians University Munich</institution>
,<addr-line>Munich</addr-line>
,<country>Germany</country>
,</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Varon Mateeva, Raymonda" sort="Varon Mateeva, Raymonda" uniqKey="Varon Mateeva R" first="Raymonda" last="Varon-Mateeva">Raymonda Varon-Mateeva</name>
<affiliation wicri:level="1"><nlm:aff id="af135"><institution>Institute of Human Genetics</institution>
,<addr-line>Campus Virchov Klinikum, Charite Berlin</addr-line>
,<country>Germany</country>
,</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kast, Karin" sort="Kast, Karin" uniqKey="Kast K" first="Karin" last="Kast">Karin Kast</name>
<affiliation wicri:level="1"><nlm:aff id="af136"><addr-line>Department of Gynaecology and Obstetrics</addr-line>
,<institution>University Hospital Carl Gustav Carus, Technical University Dresden</institution>
,<addr-line>Dresden</addr-line>
,<country>Germany</country>
,</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Deissler, Helmut" sort="Deissler, Helmut" uniqKey="Deissler H" first="Helmut" last="Deissler">Helmut Deissler</name>
<affiliation wicri:level="1"><nlm:aff id="af137"><addr-line>Department of Gynaecology and Obstetrics</addr-line>
,<institution>University Hospital Ulm</institution>
,<addr-line>Ulm</addr-line>
,<country>Germany</country>
,</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Niederacher, Dieter" sort="Niederacher, Dieter" uniqKey="Niederacher D" first="Dieter" last="Niederacher">Dieter Niederacher</name>
<affiliation wicri:level="1"><nlm:aff id="af138"><addr-line>Department of Gynaecology and Obstetrics</addr-line>
,<institution>University Hospital Düsseldorf, Heinrich-Heine University Düsseldorf</institution>
,<addr-line>Düsseldorf</addr-line>
,<country>Germany</country>
,</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Arnold, Norbert" sort="Arnold, Norbert" uniqKey="Arnold N" first="Norbert" last="Arnold">Norbert Arnold</name>
<affiliation wicri:level="1"><nlm:aff id="af139"><addr-line>Department of Gynaecology and Obstetrics</addr-line>
,<institution>University Hospital of Schleswig-Holstein, Campus Kiel, Christian-Albrechts University Kiel</institution>
,<addr-line>Kiel</addr-line>
,<country>Germany</country>
,</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gadzicki, Dorothea" sort="Gadzicki, Dorothea" uniqKey="Gadzicki D" first="Dorothea" last="Gadzicki">Dorothea Gadzicki</name>
<affiliation wicri:level="1"><nlm:aff id="af140"><institution>Institute of Cell and Molecular Pathology, Hannover Medical School</institution>
,<addr-line>Hannover</addr-line>
,<country>Germany</country>
,</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schonbuchner, Ines" sort="Schonbuchner, Ines" uniqKey="Schonbuchner I" first="Ines" last="Schönbuchner">Ines Schönbuchner</name>
<affiliation wicri:level="1"><nlm:aff id="af141"><addr-line>Centre of Familial Breast and Ovarian Cancer, Department of Medical Genetics</addr-line>
,<institution>Institute of Human Genetics, University Würzburg</institution>
,<addr-line>Würzburg</addr-line>
,<country>Germany</country>
,</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Caldes, Trinidad" sort="Caldes, Trinidad" uniqKey="Caldes T" first="Trinidad" last="Caldes">Trinidad Caldes</name>
<affiliation wicri:level="1"><nlm:aff id="af142"><addr-line>Molecular Oncology Laboratory</addr-line>
,<institution>Hospital Clinico San Carlos</institution>
,<addr-line>Madrid</addr-line>
,<country>Spain</country>
,</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="De La Hoya, Miguel" sort="De La Hoya, Miguel" uniqKey="De La Hoya M" first="Miguel" last="De La Hoya">Miguel De La Hoya</name>
<affiliation wicri:level="1"><nlm:aff id="af142"><addr-line>Molecular Oncology Laboratory</addr-line>
,<institution>Hospital Clinico San Carlos</institution>
,<addr-line>Madrid</addr-line>
,<country>Spain</country>
,</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Nevanlinna, Heli" sort="Nevanlinna, Heli" uniqKey="Nevanlinna H" first="Heli" last="Nevanlinna">Heli Nevanlinna</name>
<affiliation><nlm:aff wicri:cut=" and" id="af143"><addr-line>Department of Obstetrics and Gynecology</addr-line>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Aittom Ki, Kristiina" sort="Aittom Ki, Kristiina" uniqKey="Aittom Ki K" first="Kristiina" last="Aittom Ki">Kristiina Aittom Ki</name>
<affiliation wicri:level="1"><nlm:aff id="af144"><addr-line>Department of Clinical Genetics</addr-line>
,<institution>Helsinki University Central Hospital</institution>
,<addr-line>Helsinki</addr-line>
,<country>Finland</country>
,</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Dumont, Martine" sort="Dumont, Martine" uniqKey="Dumont M" first="Martine" last="Dumont">Martine Dumont</name>
<affiliation><nlm:aff wicri:cut=" and" id="af5"><addr-line>Cancer Genomics Laboratory</addr-line>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Chiquette, Jocelyne" sort="Chiquette, Jocelyne" uniqKey="Chiquette J" first="Jocelyne" last="Chiquette">Jocelyne Chiquette</name>
<affiliation wicri:level="1"><nlm:aff id="af145"><addr-line>Unité de recherche en santé des populations</addr-line>
,<institution>Centre des maladies du sein Deschênes-Fabia, Centre de recherche FRSQ du Centre hospitalier affilié universitaire de Québec</institution>
,<addr-line>Québec, QC</addr-line>
,<country>Canada</country>
,</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tischkowitz, Marc" sort="Tischkowitz, Marc" uniqKey="Tischkowitz M" first="Marc" last="Tischkowitz">Marc Tischkowitz</name>
<affiliation wicri:level="1"><nlm:aff id="af146"><addr-line>Program in Cancer Genetics, Departments of Human Genetics and Oncology</addr-line>
,<institution>McGill University</institution>
,<addr-line>Montreal, QC</addr-line>
,<country>Canada</country>
,</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="af147"><institution>Lady Davis Institute, Segal Cancer Centre, Jewish General Hospital</institution>
,<addr-line>Montreal, QC</addr-line>
,<country>Canada</country>
,</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Chen, Xiaoqing" sort="Chen, Xiaoqing" uniqKey="Chen X" first="Xiaoqing" last="Chen">Xiaoqing Chen</name>
<affiliation wicri:level="1"><nlm:aff id="af7"><institution>Queensland Institute of Medical Research</institution>
,<addr-line>Brisbane</addr-line>
,<country>Australia</country>
,</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Beesley, Jonathan" sort="Beesley, Jonathan" uniqKey="Beesley J" first="Jonathan" last="Beesley">Jonathan Beesley</name>
<affiliation wicri:level="1"><nlm:aff id="af7"><institution>Queensland Institute of Medical Research</institution>
,<addr-line>Brisbane</addr-line>
,<country>Australia</country>
,</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Spurdle, Amanda B" sort="Spurdle, Amanda B" uniqKey="Spurdle A" first="Amanda B." last="Spurdle">Amanda B. Spurdle</name>
<affiliation wicri:level="1"><nlm:aff id="af7"><institution>Queensland Institute of Medical Research</institution>
,<addr-line>Brisbane</addr-line>
,<country>Australia</country>
,</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Neuhausen, Susan L" sort="Neuhausen, Susan L" uniqKey="Neuhausen S" first="Susan L." last="Neuhausen">Susan L. Neuhausen</name>
<affiliation wicri:level="1"><nlm:aff id="af148"><addr-line>Department of Population Sciences</addr-line>
,<institution>Beckman Research Institute of the City of Hope</institution>
, Duarte,<addr-line>CA</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Chun Ding, Yuan" sort="Chun Ding, Yuan" uniqKey="Chun Ding Y" first="Yuan" last="Chun Ding">Yuan Chun Ding</name>
<affiliation wicri:level="1"><nlm:aff id="af148"><addr-line>Department of Population Sciences</addr-line>
,<institution>Beckman Research Institute of the City of Hope</institution>
, Duarte,<addr-line>CA</addr-line>
,<country>USA</country>
,</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Fredericksen, Zachary" sort="Fredericksen, Zachary" uniqKey="Fredericksen Z" first="Zachary" last="Fredericksen">Zachary Fredericksen</name>
<affiliation wicri:level="1"><nlm:aff wicri:cut=" and" id="af149"><addr-line>Department of Health Sciences Research</addr-line>
,<institution>Mayo Clinic</institution>
,<addr-line>Rochester, MN</addr-line>
,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wang, Xianshu" sort="Wang, Xianshu" uniqKey="Wang X" first="Xianshu" last="Wang">Xianshu Wang</name>
<affiliation wicri:level="1"><nlm:aff id="af150"><addr-line>Department of Laboratory Medicine and Pathology</addr-line>
,<institution>Mayo Clinic</institution>
,<addr-line>Rochester, MN</addr-line>
,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pankratz, Vernon S" sort="Pankratz, Vernon S" uniqKey="Pankratz V" first="Vernon S." last="Pankratz">Vernon S. Pankratz</name>
<affiliation wicri:level="1"><nlm:aff wicri:cut=" and" id="af149"><addr-line>Department of Health Sciences Research</addr-line>
,<institution>Mayo Clinic</institution>
,<addr-line>Rochester, MN</addr-line>
,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Couch, Fergus" sort="Couch, Fergus" uniqKey="Couch F" first="Fergus" last="Couch">Fergus Couch</name>
<affiliation wicri:level="1"><nlm:aff id="af150"><addr-line>Department of Laboratory Medicine and Pathology</addr-line>
,<institution>Mayo Clinic</institution>
,<addr-line>Rochester, MN</addr-line>
,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Simard, Jacques" sort="Simard, Jacques" uniqKey="Simard J" first="Jacques" last="Simard">Jacques Simard</name>
<affiliation wicri:level="1"><nlm:aff id="af6"><addr-line>Canada Research Chair in Oncogenetics, Cancer Genomics Laboratory</addr-line>
,<institution>Centre Hospitalier Universitaire de Québec and Laval University</institution>
,<addr-line>2705 Laurier Boulevard, T3-57, Quebec City, QC</addr-line>
,<country>Canada</country>
,</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F." last="Easton">Douglas F. Easton</name>
<affiliation><nlm:aff wicri:cut=" and" id="af1"><addr-line>Department of Public Health and Primary Care</addr-line>
,<institution>Centre for Cancer Genetic Epidemiology</institution>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Chenevix Trench, Georgia" sort="Chenevix Trench, Georgia" uniqKey="Chenevix Trench G" first="Georgia" last="Chenevix-Trench">Georgia Chenevix-Trench</name>
<affiliation wicri:level="1"><nlm:aff id="af7"><institution>Queensland Institute of Medical Research</institution>
,<addr-line>Brisbane</addr-line>
,<country>Australia</country>
,</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
</analytic>
<series><title level="j">Human Molecular Genetics</title>
<idno type="ISSN">0964-6906</idno>
<idno type="eISSN">1460-2083</idno>
<imprint><date when="2011">2011</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>Two single nucleotide polymorphisms (SNPs) at 6q25.1, near the <italic>ESR1</italic>
gene, have been implicated in the susceptibility to breast cancer for Asian (rs2046210) and European women (rs9397435). A genome-wide association study in Europeans identified two further breast cancer susceptibility variants: rs11249433 at 1p11.2 and rs999737 in <italic>RAD51L1</italic>
at 14q24.1. Although previously identified breast cancer susceptibility variants have been shown to be associated with breast cancer risk for <italic>BRCA1</italic>
and <italic>BRCA2</italic>
mutation carriers, the involvement of these SNPs to breast cancer susceptibility in mutation carriers is currently unknown. To address this, we genotyped these SNPs in <italic>BRCA1</italic>
and <italic>BRCA2</italic>
mutation carriers from 42 studies from the Consortium of Investigators of Modifiers of <italic>BRCA1/2</italic>
<italic>.</italic>
In the analysis of 14 123 <italic>BRCA1</italic>
and 8053 <italic>BRCA2</italic>
mutation carriers of European ancestry, the 6q25.1 SNPs (<italic>r</italic>
<sup>2</sup>
= 0.14) were independently associated with the risk of breast cancer for <italic>BRCA1</italic>
mutation carriers [hazard ratio (HR) = 1.17, 95% confidence interval (CI): 1.11–1.23, <italic>P</italic>
-trend = 4.5 × 10<sup>−9</sup>
for rs2046210; HR = 1.28, 95% CI: 1.18–1.40, <italic>P</italic>
-trend = 1.3 × 10<sup>−8</sup>
for rs9397435], but only rs9397435 was associated with the risk for <italic>BRCA2</italic>
carriers (HR = 1.14, 95% CI: 1.01–1.28, <italic>P</italic>
-trend = 0.031). SNP rs11249433 (1p11.2) was associated with the risk of breast cancer for <italic>BRCA2</italic>
mutation carriers (HR = 1.09, 95% CI: 1.02–1.17, <italic>P</italic>
-trend = 0.015), but was not associated with breast cancer risk for <italic>BRCA1</italic>
mutation carriers (HR = 0.97, 95% CI: 0.92–1.02, <italic>P</italic>
-trend = 0.20). SNP rs999737 (<italic>RAD51L1</italic>
) was not associated with breast cancer risk for either <italic>BRCA1</italic>
or <italic>BRCA2</italic>
mutation carriers (<italic>P</italic>
-trend = 0.27 and 0.30, respectively). The identification of SNPs at 6q25.1 associated with breast cancer risk for <italic>BRCA1</italic>
mutation carriers will lead to a better understanding of the biology of tumour development in these women.</p>
</div>
</front>
</TEI>
<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Hum Mol Genet</journal-id>
<journal-id journal-id-type="iso-abbrev">Hum. Mol. Genet</journal-id>
<journal-id journal-id-type="publisher-id">hmg</journal-id>
<journal-id journal-id-type="hwp">hmg</journal-id>
<journal-title-group><journal-title>Human Molecular Genetics</journal-title>
</journal-title-group>
<issn pub-type="ppub">0964-6906</issn>
<issn pub-type="epub">1460-2083</issn>
<publisher><publisher-name>Oxford University Press</publisher-name>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">21593217</article-id>
<article-id pub-id-type="pmc">3652640</article-id>
<article-id pub-id-type="doi">10.1093/hmg/ddr226</article-id>
<article-id pub-id-type="publisher-id">ddr226</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Association Studies Articles</subject>
</subj-group>
</article-categories>
<title-group><article-title>Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for <italic>BRCA1</italic>
and <italic>BRCA2</italic>
mutation carriers</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Antoniou</surname>
<given-names>Antonis C</given-names>
</name>
<xref ref-type="aff" rid="af1">1</xref>
<xref ref-type="corresp" rid="cor1">*</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kartsonaki</surname>
<given-names>Christiana</given-names>
</name>
<xref ref-type="aff" rid="af1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Sinilnikova</surname>
<given-names>Olga M.</given-names>
</name>
<xref ref-type="aff" rid="af3">3</xref>
<xref ref-type="aff" rid="af4">4</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Soucy</surname>
<given-names>Penny</given-names>
</name>
<xref ref-type="aff" rid="af5">5</xref>
</contrib>
<contrib contrib-type="author"><name><surname>McGuffog</surname>
<given-names>Lesley</given-names>
</name>
<xref ref-type="aff" rid="af1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Healey</surname>
<given-names>Sue</given-names>
</name>
<xref ref-type="aff" rid="af7">7</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Lee</surname>
<given-names>Andrew</given-names>
</name>
<xref ref-type="aff" rid="af1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Peterlongo</surname>
<given-names>Paolo</given-names>
</name>
<xref ref-type="aff" rid="af9">9</xref>
<xref ref-type="aff" rid="af11">11</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Manoukian</surname>
<given-names>Siranoush</given-names>
</name>
<xref ref-type="aff" rid="af12">12</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Peissel</surname>
<given-names>Bernard</given-names>
</name>
<xref ref-type="aff" rid="af12">12</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Zaffaroni</surname>
<given-names>Daniela</given-names>
</name>
<xref ref-type="aff" rid="af12">12</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Cattaneo</surname>
<given-names>Elisa</given-names>
</name>
<xref ref-type="aff" rid="af10">10</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Barile</surname>
<given-names>Monica</given-names>
</name>
<xref ref-type="aff" rid="af14">14</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Pensotti</surname>
<given-names>Valeria</given-names>
</name>
<xref ref-type="aff" rid="af15">15</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Pasini</surname>
<given-names>Barbara</given-names>
</name>
<xref ref-type="aff" rid="af16">16</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Dolcetti</surname>
<given-names>Riccardo</given-names>
</name>
<xref ref-type="aff" rid="af17">17</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Giannini</surname>
<given-names>Giuseppe</given-names>
</name>
<xref ref-type="aff" rid="af18">18</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Laura Putignano</surname>
<given-names>Anna</given-names>
</name>
<xref ref-type="aff" rid="af19">19</xref>
<xref ref-type="aff" rid="af20">20</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Varesco</surname>
<given-names>Liliana</given-names>
</name>
<xref ref-type="aff" rid="af21">21</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Radice</surname>
<given-names>Paolo</given-names>
</name>
<xref ref-type="aff" rid="af9">9</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Mai</surname>
<given-names>Phuong L.</given-names>
</name>
<xref ref-type="aff" rid="af22">22</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Greene</surname>
<given-names>Mark H.</given-names>
</name>
<xref ref-type="aff" rid="af22">22</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Andrulis</surname>
<given-names>Irene L.</given-names>
</name>
<xref ref-type="aff" rid="af23">23</xref>
<xref ref-type="aff" rid="af24">24</xref>
<xref ref-type="aff" rid="af25">25</xref>
<xref ref-type="aff" rid="af27">27</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Glendon</surname>
<given-names>Gord</given-names>
</name>
<xref ref-type="aff" rid="af27">27</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Ozcelik</surname>
<given-names>Hilmi</given-names>
</name>
<xref ref-type="aff" rid="af23">23</xref>
<xref ref-type="aff" rid="af26">26</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Thomassen</surname>
<given-names>Mads</given-names>
</name>
<xref ref-type="aff" rid="af28">28</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Gerdes</surname>
<given-names>Anne-Marie</given-names>
</name>
<xref ref-type="aff" rid="af29">29</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kruse</surname>
<given-names>Torben A.</given-names>
</name>
<xref ref-type="aff" rid="af28">28</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Birk Jensen</surname>
<given-names>Uffe</given-names>
</name>
<xref ref-type="aff" rid="af30">30</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Crüger</surname>
<given-names>Dorthe G.</given-names>
</name>
<xref ref-type="aff" rid="af31">31</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Caligo</surname>
<given-names>Maria A.</given-names>
</name>
<xref ref-type="aff" rid="af32">32</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Laitman</surname>
<given-names>Yael</given-names>
</name>
<xref ref-type="aff" rid="af33">33</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Milgrom</surname>
<given-names>Roni</given-names>
</name>
<xref ref-type="aff" rid="af33">33</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kaufman</surname>
<given-names>Bella</given-names>
</name>
<xref ref-type="aff" rid="af34">34</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Paluch-Shimon</surname>
<given-names>Shani</given-names>
</name>
<xref ref-type="aff" rid="af34">34</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Friedman</surname>
<given-names>Eitan</given-names>
</name>
<xref ref-type="aff" rid="af33">33</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Loman</surname>
<given-names>Niklas</given-names>
</name>
<xref ref-type="aff" rid="af35">35</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Harbst</surname>
<given-names>Katja</given-names>
</name>
<xref ref-type="aff" rid="af35">35</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Lindblom</surname>
<given-names>Annika</given-names>
</name>
<xref ref-type="aff" rid="af36">36</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Arver</surname>
<given-names>Brita</given-names>
</name>
<xref ref-type="aff" rid="af37">37</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Ehrencrona</surname>
<given-names>Hans</given-names>
</name>
<xref ref-type="aff" rid="af38">38</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Melin</surname>
<given-names>Beatrice</given-names>
</name>
<xref ref-type="aff" rid="af39">39</xref>
</contrib>
<contrib contrib-type="author"><collab>SWE-BRCA</collab>
<xref ref-type="aff" rid="af35">35</xref>
<xref ref-type="aff" rid="af36">36</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Nathanson</surname>
<given-names>Katherine L.</given-names>
</name>
<xref ref-type="aff" rid="af40">40</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Domchek</surname>
<given-names>Susan M.</given-names>
</name>
<xref ref-type="aff" rid="af40">40</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Rebbeck</surname>
<given-names>Timothy</given-names>
</name>
<xref ref-type="aff" rid="af40">40</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Jakubowska</surname>
<given-names>Ania</given-names>
</name>
<xref ref-type="aff" rid="af41">41</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Lubinski</surname>
<given-names>Jan</given-names>
</name>
<xref ref-type="aff" rid="af41">41</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Gronwald</surname>
<given-names>Jacek</given-names>
</name>
<xref ref-type="aff" rid="af41">41</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Huzarski</surname>
<given-names>Tomasz</given-names>
</name>
<xref ref-type="aff" rid="af41">41</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Byrski</surname>
<given-names>Tomasz</given-names>
</name>
<xref ref-type="aff" rid="af41">41</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Cybulski</surname>
<given-names>Cezary</given-names>
</name>
<xref ref-type="aff" rid="af41">41</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Gorski</surname>
<given-names>Bohdan</given-names>
</name>
<xref ref-type="aff" rid="af41">41</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Osorio</surname>
<given-names>Ana</given-names>
</name>
<xref ref-type="aff" rid="af42">42</xref>
<xref ref-type="aff" rid="af43">43</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Ramón y Cajal</surname>
<given-names>Teresa</given-names>
</name>
<xref ref-type="aff" rid="af44">44</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Fostira</surname>
<given-names>Florentia</given-names>
</name>
<xref ref-type="aff" rid="af45">45</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Andrés</surname>
<given-names>Raquel</given-names>
</name>
<xref ref-type="aff" rid="af46">46</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Benitez</surname>
<given-names>Javier</given-names>
</name>
<xref ref-type="aff" rid="af42">42</xref>
<xref ref-type="aff" rid="af43">43</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Hamann</surname>
<given-names>Ute</given-names>
</name>
<xref ref-type="aff" rid="af47">47</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Hogervorst</surname>
<given-names>Frans B.</given-names>
</name>
<xref ref-type="aff" rid="af48">48</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Rookus</surname>
<given-names>Matti A.</given-names>
</name>
<xref ref-type="aff" rid="af49">49</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Hooning</surname>
<given-names>Maartje J.</given-names>
</name>
<xref ref-type="aff" rid="af50">50</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Nelen</surname>
<given-names>Marcel R.</given-names>
</name>
<xref ref-type="aff" rid="af51">51</xref>
</contrib>
<contrib contrib-type="author"><name><surname>van der Luijt</surname>
<given-names>Rob B.</given-names>
</name>
<xref ref-type="aff" rid="af52">52</xref>
</contrib>
<contrib contrib-type="author"><name><surname>van Os</surname>
<given-names>Theo A.M.</given-names>
</name>
<xref ref-type="aff" rid="af53">53</xref>
</contrib>
<contrib contrib-type="author"><name><surname>van Asperen</surname>
<given-names>Christi J.</given-names>
</name>
<xref ref-type="aff" rid="af54">54</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Devilee</surname>
<given-names>Peter</given-names>
</name>
<xref ref-type="aff" rid="af55">55</xref>
<xref ref-type="aff" rid="af56">56</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Meijers-Heijboer</surname>
<given-names>Hanne E.J.</given-names>
</name>
<xref ref-type="aff" rid="af57">57</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Gómez Garcia</surname>
<given-names>Encarna B.</given-names>
</name>
<xref ref-type="aff" rid="af58">58</xref>
<xref ref-type="aff" rid="af59">59</xref>
</contrib>
<contrib contrib-type="author"><collab>HEBON</collab>
<xref ref-type="aff" rid="af49">49</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Peock</surname>
<given-names>Susan</given-names>
</name>
<xref ref-type="aff" rid="af1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Cook</surname>
<given-names>Margaret</given-names>
</name>
<xref ref-type="aff" rid="af1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Frost</surname>
<given-names>Debra</given-names>
</name>
<xref ref-type="aff" rid="af1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Platte</surname>
<given-names>Radka</given-names>
</name>
<xref ref-type="aff" rid="af1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Leyland</surname>
<given-names>Jean</given-names>
</name>
<xref ref-type="aff" rid="af1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Gareth Evans</surname>
<given-names>D.</given-names>
</name>
<xref ref-type="aff" rid="af60">60</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Lalloo</surname>
<given-names>Fiona</given-names>
</name>
<xref ref-type="aff" rid="af60">60</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Eeles</surname>
<given-names>Ros</given-names>
</name>
<xref ref-type="aff" rid="af61">61</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Izatt</surname>
<given-names>Louise</given-names>
</name>
<xref ref-type="aff" rid="af62">62</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Adlard</surname>
<given-names>Julian</given-names>
</name>
<xref ref-type="aff" rid="af63">63</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Davidson</surname>
<given-names>Rosemarie</given-names>
</name>
<xref ref-type="aff" rid="af64">64</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Eccles</surname>
<given-names>Diana</given-names>
</name>
<xref ref-type="aff" rid="af65">65</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Ong</surname>
<given-names>Kai-ren</given-names>
</name>
<xref ref-type="aff" rid="af66">66</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Cook</surname>
<given-names>Jackie</given-names>
</name>
<xref ref-type="aff" rid="af67">67</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Douglas</surname>
<given-names>Fiona</given-names>
</name>
<xref ref-type="aff" rid="af68">68</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Paterson</surname>
<given-names>Joan</given-names>
</name>
<xref ref-type="aff" rid="af69">69</xref>
</contrib>
<contrib contrib-type="author"><name><surname>John Kennedy</surname>
<given-names>M.</given-names>
</name>
<xref ref-type="aff" rid="af70">70</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Miedzybrodzka</surname>
<given-names>Zosia</given-names>
</name>
<xref ref-type="aff" rid="af71">71</xref>
</contrib>
<contrib contrib-type="author"><collab>EMBRACE</collab>
<xref ref-type="aff" rid="af1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Godwin</surname>
<given-names>Andrew</given-names>
</name>
<xref ref-type="aff" rid="af72">72</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Stoppa-Lyonnet</surname>
<given-names>Dominique</given-names>
</name>
<xref ref-type="aff" rid="af73">73</xref>
<xref ref-type="aff" rid="af74">74</xref>
<xref ref-type="aff" rid="af75">75</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Buecher</surname>
<given-names>Bruno</given-names>
</name>
<xref ref-type="aff" rid="af73">73</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Belotti</surname>
<given-names>Muriel</given-names>
</name>
<xref ref-type="aff" rid="af73">73</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Tirapo</surname>
<given-names>Carole</given-names>
</name>
<xref ref-type="aff" rid="af73">73</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Mazoyer</surname>
<given-names>Sylvie</given-names>
</name>
<xref ref-type="aff" rid="af4">4</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Barjhoux</surname>
<given-names>Laure</given-names>
</name>
<xref ref-type="aff" rid="af4">4</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Lasset</surname>
<given-names>Christine</given-names>
</name>
<xref ref-type="aff" rid="af76">76</xref>
<xref ref-type="aff" rid="af77">77</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Leroux</surname>
<given-names>Dominique</given-names>
</name>
<xref ref-type="aff" rid="af78">78</xref>
<xref ref-type="aff" rid="af79">79</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Faivre</surname>
<given-names>Laurence</given-names>
</name>
<xref ref-type="aff" rid="af80">80</xref>
<xref ref-type="aff" rid="af81">81</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Bronner</surname>
<given-names>Myriam</given-names>
</name>
<xref ref-type="aff" rid="af82">82</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Prieur</surname>
<given-names>Fabienne</given-names>
</name>
<xref ref-type="aff" rid="af83">83</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Nogues</surname>
<given-names>Catherine</given-names>
</name>
<xref ref-type="aff" rid="af84">84</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Rouleau</surname>
<given-names>Etienne</given-names>
</name>
<xref ref-type="aff" rid="af85">85</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Pujol</surname>
<given-names>Pascal</given-names>
</name>
<xref ref-type="aff" rid="af86">86</xref>
<xref ref-type="aff" rid="af87">87</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Coupier</surname>
<given-names>Isabelle</given-names>
</name>
<xref ref-type="aff" rid="af86">86</xref>
<xref ref-type="aff" rid="af88">88</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Frénay</surname>
<given-names>Marc</given-names>
</name>
<xref ref-type="aff" rid="af89">89</xref>
</contrib>
<contrib contrib-type="author"><collab>CEMO Study Collaborators</collab>
<xref ref-type="aff" rid="af3">3</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Hopper</surname>
<given-names>John L.</given-names>
</name>
<xref ref-type="aff" rid="af90">90</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Daly</surname>
<given-names>Mary B.</given-names>
</name>
<xref ref-type="aff" rid="af91">91</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Terry</surname>
<given-names>Mary B.</given-names>
</name>
<xref ref-type="aff" rid="af92">92</xref>
</contrib>
<contrib contrib-type="author"><name><surname>John</surname>
<given-names>Esther M.</given-names>
</name>
<xref ref-type="aff" rid="af93">93</xref>
<xref ref-type="aff" rid="af94">94</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Buys</surname>
<given-names>Saundra S.</given-names>
</name>
<xref ref-type="aff" rid="af95">95</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Yassin</surname>
<given-names>Yosuf</given-names>
</name>
<xref ref-type="aff" rid="af96">96</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Miron</surname>
<given-names>Alexander</given-names>
</name>
<xref ref-type="aff" rid="af96">96</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Goldgar</surname>
<given-names>David</given-names>
</name>
<xref ref-type="aff" rid="af97">97</xref>
</contrib>
<contrib contrib-type="author"><collab>Breast Cancer Family Registry</collab>
</contrib>
<contrib contrib-type="author"><name><surname>Singer</surname>
<given-names>Christian F.</given-names>
</name>
<xref ref-type="aff" rid="af98">98</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Tea</surname>
<given-names>Muy-Kheng</given-names>
</name>
<xref ref-type="aff" rid="af98">98</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Pfeiler</surname>
<given-names>Georg</given-names>
</name>
<xref ref-type="aff" rid="af98">98</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Catharina Dressler</surname>
<given-names>Anne</given-names>
</name>
<xref ref-type="aff" rid="af98">98</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Hansen</surname>
<given-names>Thomas v.O.</given-names>
</name>
<xref ref-type="aff" rid="af99">99</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Jønson</surname>
<given-names>Lars</given-names>
</name>
<xref ref-type="aff" rid="af99">99</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Ejlertsen</surname>
<given-names>Bent</given-names>
</name>
<xref ref-type="aff" rid="af100">100</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Bjork Barkardottir</surname>
<given-names>Rosa</given-names>
</name>
<xref ref-type="aff" rid="af101">101</xref>
<xref ref-type="aff" rid="af102">102</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kirchhoff</surname>
<given-names>Tomas</given-names>
</name>
<xref ref-type="aff" rid="af103">103</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Offit</surname>
<given-names>Kenneth</given-names>
</name>
<xref ref-type="aff" rid="af103">103</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Piedmonte</surname>
<given-names>Marion</given-names>
</name>
<xref ref-type="aff" rid="af104">104</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Rodriguez</surname>
<given-names>Gustavo</given-names>
</name>
<xref ref-type="aff" rid="af106">106</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Small</surname>
<given-names>Laurie</given-names>
</name>
<xref ref-type="aff" rid="af107">107</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Boggess</surname>
<given-names>John</given-names>
</name>
<xref ref-type="aff" rid="af108">108</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Blank</surname>
<given-names>Stephanie</given-names>
</name>
<xref ref-type="aff" rid="af109">109</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Basil</surname>
<given-names>Jack</given-names>
</name>
<xref ref-type="aff" rid="af110">110</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Azodi</surname>
<given-names>Masoud</given-names>
</name>
<xref ref-type="aff" rid="af111">111</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Ewart Toland</surname>
<given-names>Amanda</given-names>
</name>
<xref ref-type="aff" rid="af112">112</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Montagna</surname>
<given-names>Marco</given-names>
</name>
<xref ref-type="aff" rid="af113">113</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Tognazzo</surname>
<given-names>Silvia</given-names>
</name>
<xref ref-type="aff" rid="af113">113</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Agata</surname>
<given-names>Simona</given-names>
</name>
<xref ref-type="aff" rid="af113">113</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Imyanitov</surname>
<given-names>Evgeny</given-names>
</name>
<xref ref-type="aff" rid="af114">114</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Janavicius</surname>
<given-names>Ramunas</given-names>
</name>
<xref ref-type="aff" rid="af115">115</xref>
<xref ref-type="aff" rid="af116">116</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Lazaro</surname>
<given-names>Conxi</given-names>
</name>
<xref ref-type="aff" rid="af117">117</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Blanco</surname>
<given-names>Ignacio</given-names>
</name>
<xref ref-type="aff" rid="af117">117</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Pharoah</surname>
<given-names>Paul D.P.</given-names>
</name>
<xref ref-type="aff" rid="af2">2</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Sucheston</surname>
<given-names>Lara</given-names>
</name>
<xref ref-type="aff" rid="af105">105</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Karlan</surname>
<given-names>Beth Y.</given-names>
</name>
<xref ref-type="aff" rid="af118">118</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Walsh</surname>
<given-names>Christine S.</given-names>
</name>
<xref ref-type="aff" rid="af118">118</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Olah</surname>
<given-names>Edith</given-names>
</name>
<xref ref-type="aff" rid="af119">119</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Bozsik</surname>
<given-names>Aniko</given-names>
</name>
<xref ref-type="aff" rid="af119">119</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Teo</surname>
<given-names>Soo-Hwang</given-names>
</name>
<xref ref-type="aff" rid="af120">120</xref>
<xref ref-type="aff" rid="af121">121</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Seldon</surname>
<given-names>Joyce L.</given-names>
</name>
<xref ref-type="aff" rid="af122">122</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Beattie</surname>
<given-names>Mary S.</given-names>
</name>
<xref ref-type="aff" rid="af123">123</xref>
<xref ref-type="aff" rid="af124">124</xref>
<xref ref-type="aff" rid="af125">125</xref>
<xref ref-type="aff" rid="af126">126</xref>
</contrib>
<contrib contrib-type="author"><name><surname>van Rensburg</surname>
<given-names>Elizabeth J.</given-names>
</name>
<xref ref-type="aff" rid="af127">127</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Sluiter</surname>
<given-names>Michelle D.</given-names>
</name>
<xref ref-type="aff" rid="af127">127</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Diez</surname>
<given-names>Orland</given-names>
</name>
<xref ref-type="aff" rid="af128">128</xref>
<xref ref-type="aff" rid="af129">129</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Schmutzler</surname>
<given-names>Rita K.</given-names>
</name>
<xref ref-type="aff" rid="af130">130</xref>
<xref ref-type="aff" rid="af131">131</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Wappenschmidt</surname>
<given-names>Barbara</given-names>
</name>
<xref ref-type="aff" rid="af130">130</xref>
<xref ref-type="aff" rid="af131">131</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Engel</surname>
<given-names>Christoph</given-names>
</name>
<xref ref-type="aff" rid="af132">132</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Meindl</surname>
<given-names>Alfons</given-names>
</name>
<xref ref-type="aff" rid="af133">133</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Ruehl</surname>
<given-names>Ina</given-names>
</name>
<xref ref-type="aff" rid="af134">134</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Varon-Mateeva</surname>
<given-names>Raymonda</given-names>
</name>
<xref ref-type="aff" rid="af135">135</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kast</surname>
<given-names>Karin</given-names>
</name>
<xref ref-type="aff" rid="af136">136</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Deissler</surname>
<given-names>Helmut</given-names>
</name>
<xref ref-type="aff" rid="af137">137</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Niederacher</surname>
<given-names>Dieter</given-names>
</name>
<xref ref-type="aff" rid="af138">138</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Arnold</surname>
<given-names>Norbert</given-names>
</name>
<xref ref-type="aff" rid="af139">139</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Gadzicki</surname>
<given-names>Dorothea</given-names>
</name>
<xref ref-type="aff" rid="af140">140</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Schönbuchner</surname>
<given-names>Ines</given-names>
</name>
<xref ref-type="aff" rid="af141">141</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Caldes</surname>
<given-names>Trinidad</given-names>
</name>
<xref ref-type="aff" rid="af142">142</xref>
</contrib>
<contrib contrib-type="author"><name><surname>de la Hoya</surname>
<given-names>Miguel</given-names>
</name>
<xref ref-type="aff" rid="af142">142</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Nevanlinna</surname>
<given-names>Heli</given-names>
</name>
<xref ref-type="aff" rid="af143">143</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Aittomäki</surname>
<given-names>Kristiina</given-names>
</name>
<xref ref-type="aff" rid="af144">144</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Dumont</surname>
<given-names>Martine</given-names>
</name>
<xref ref-type="aff" rid="af5">5</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Chiquette</surname>
<given-names>Jocelyne</given-names>
</name>
<xref ref-type="aff" rid="af145">145</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Tischkowitz</surname>
<given-names>Marc</given-names>
</name>
<xref ref-type="aff" rid="af146">146</xref>
<xref ref-type="aff" rid="af147">147</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Chen</surname>
<given-names>Xiaoqing</given-names>
</name>
<xref ref-type="aff" rid="af7">7</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Beesley</surname>
<given-names>Jonathan</given-names>
</name>
<xref ref-type="aff" rid="af7">7</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Spurdle</surname>
<given-names>Amanda B.</given-names>
</name>
<xref ref-type="aff" rid="af7">7</xref>
</contrib>
<contrib contrib-type="author"><collab>kConFab investigators</collab>
<xref ref-type="aff" rid="af8">8</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Neuhausen</surname>
<given-names>Susan L.</given-names>
</name>
<xref ref-type="aff" rid="af148">148</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Chun Ding</surname>
<given-names>Yuan</given-names>
</name>
<xref ref-type="aff" rid="af148">148</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Fredericksen</surname>
<given-names>Zachary</given-names>
</name>
<xref ref-type="aff" rid="af149">149</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Wang</surname>
<given-names>Xianshu</given-names>
</name>
<xref ref-type="aff" rid="af150">150</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Pankratz</surname>
<given-names>Vernon S.</given-names>
</name>
<xref ref-type="aff" rid="af149">149</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Couch</surname>
<given-names>Fergus</given-names>
</name>
<xref ref-type="aff" rid="af150">150</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Simard</surname>
<given-names>Jacques</given-names>
</name>
<xref ref-type="aff" rid="af6">6</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Easton</surname>
<given-names>Douglas F.</given-names>
</name>
<xref ref-type="aff" rid="af1">1</xref>
<xref ref-type="author-notes" rid="AN1">†</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Chenevix-Trench</surname>
<given-names>Georgia</given-names>
</name>
<xref ref-type="aff" rid="af7">7</xref>
<xref ref-type="author-notes" rid="AN1">†</xref>
</contrib>
</contrib-group>
<contrib-group><contrib contrib-type="author"><collab>on behalf of CIMBA</collab>
<xref ref-type="aff" rid="af27">27</xref>
</contrib>
</contrib-group>
<aff id="af1"><label>1</label>
<addr-line>Department of Public Health and Primary Care</addr-line>
,<institution>Centre for Cancer Genetic Epidemiology</institution>
and</aff>
<aff id="af2"><label>2</label>
<addr-line>Department of Oncology</addr-line>
,<institution>University of Cambridge</institution>
,<addr-line>Cambridge</addr-line>
,<country>UK</country>
,</aff>
<aff id="af3"><label>3</label>
<institution>Centre Hospitalier Universitaire de Lyon/Centre Léon Bérard, Unité Mixte de Génétique Constitutionnelle des Cancers Fréquents</institution>
,<addr-line>Lyon</addr-line>
,<country>France</country>
,</aff>
<aff id="af4"><label>4</label>
<addr-line>Equipe labellisée LIGUE 2008, UMR5201 CNRS, Centre Léon Bérard</addr-line>
,<institution>Université de Lyon</institution>
,<addr-line>Lyon</addr-line>
,<country>France</country>
,</aff>
<aff id="af5"><label>5</label>
<addr-line>Cancer Genomics Laboratory</addr-line>
and</aff>
<aff id="af6"><label>6</label>
<addr-line>Canada Research Chair in Oncogenetics, Cancer Genomics Laboratory</addr-line>
,<institution>Centre Hospitalier Universitaire de Québec and Laval University</institution>
,<addr-line>2705 Laurier Boulevard, T3-57, Quebec City, QC</addr-line>
,<country>Canada</country>
,</aff>
<aff id="af7"><label>7</label>
<institution>Queensland Institute of Medical Research</institution>
,<addr-line>Brisbane</addr-line>
,<country>Australia</country>
,</aff>
<aff id="af8"><label>8</label>
<addr-line>kConFab: Kathleen Cuningham Consortium for Research into Familial Breast Cancer</addr-line>
,<institution>Peter MacCallum Cancer Center</institution>
,<addr-line>Melbourne</addr-line>
,<country>Australia</country>
,</aff>
<aff id="af9"><label>9</label>
<addr-line>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine</addr-line>
and</aff>
<aff id="af10"><label>10</label>
<addr-line>Unit of Medical Genetics, Department of Preventive and Predicted Medicine</addr-line>
,<institution>Fondazione IRCCS Istituto Nazionale Tumori (INT)</institution>
,<addr-line>Milan</addr-line>
,<country>Italy</country>
,</aff>
<aff id="af11"><label>11</label>
<addr-line>IFOM</addr-line>
,<institution>Fondazione Istituto FIRC di Oncologia Molecolare</institution>
,<addr-line>Milan</addr-line>
,<country>Italy</country>
,</aff>
<aff id="af12"><label>12</label>
<addr-line>Unit of Medical Genetics, Department of Preventive and Predicted Medicine</addr-line>
,<institution>Fondazione IRCCS Istituto Nazionale Tumori (INT)</institution>
,<addr-line>Milan</addr-line>
,<country>Italy</country>
,</aff>
<aff id="af13"><label>13</label>
<addr-line>Department of Medicine, Surgery and Dentistry</addr-line>
,<institution>Università degli Studi di Milano, Medical Genetics</institution>
,<addr-line>Milan</addr-line>
,<country>Italy</country>
,</aff>
<aff id="af14"><label>14</label>
<addr-line>Division of Cancer Prevention and Genetics</addr-line>
,<institution>Istituto Europeo di Oncologia (IEO)</institution>
,<addr-line>Milan</addr-line>
,<country>Italy</country>
,</aff>
<aff id="af15"><label>15</label>
<addr-line>Cogentech</addr-line>
,<institution>Consortium for Genomics Technology</institution>
,<addr-line>Milan</addr-line>
,<country>Italy</country>
,</aff>
<aff id="af16"><label>16</label>
<addr-line>Department of Genetics, Biology and Biochemistry</addr-line>
,<institution>University of Turin</institution>
,<addr-line>Turin</addr-line>
,<country>Italy</country>
,</aff>
<aff id="af17"><label>17</label>
<addr-line>Cancer Bioimmunotherapy Unit</addr-line>
,<institution>Centro di Riferimento Oncologico, IRCCS</institution>
,<addr-line>Aviano (PN)</addr-line>
,<country>Italy</country>
,</aff>
<aff id="af18"><label>18</label>
<addr-line>Department of Experimental Medicine</addr-line>
,<institution>University La Sapienza</institution>
,<addr-line>Rome</addr-line>
,<country>Italy</country>
,</aff>
<aff id="af19"><label>19</label>
<addr-line>Department of Clinical Physiopathology</addr-line>
,<institution>University of Florence</institution>
,<addr-line>Florence</addr-line>
,<country>Italy</country>
,</aff>
<aff id="af20"><label>20</label>
<institution>Fiorgen Foundation for Pharmacogenomics</institution>
,<addr-line>Sesto Fiorentino</addr-line>
,<country>Italy</country>
,</aff>
<aff id="af21"><label>21</label>
<addr-line>Unit of Hereditary Cancer, Department of Epidemiology, Prevention and Special Functions</addr-line>
,<institution>Istituto Nazionale per la Ricerca sul Cancro (IST)</institution>
,<addr-line>Genoa</addr-line>
,<country>Italy</country>
,</aff>
<aff id="af22"><label>22</label>
<addr-line>Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics</addr-line>
,<institution>US National Cancer Institute</institution>
,<addr-line>Rockville MD</addr-line>
,<country>USA</country>
,</aff>
<aff id="af23"><label>23</label>
<institution>Samuel Lunenfeld Research Institute, Mount Sinai Hospital</institution>
,<addr-line>Toronto, ON</addr-line>
,<country>Canada</country>
,</aff>
<aff id="af24"><label>24</label>
<addr-line>Department of Molecular Genetics</addr-line>
,</aff>
<aff id="af25"><label>25</label>
<addr-line>Department of Laboratory Medicine and Pathobiology</addr-line>
and</aff>
<aff id="af26"><label>26</label>
<addr-line>Department of Laboratory Medicine and Pathobiology</addr-line>
,<institution>University of Toronto</institution>
,<addr-line>Toronto, ON</addr-line>
,<country>Canada</country>
,</aff>
<aff id="af27"><label>27</label>
<institution>Cancer Care Ontario</institution>
,<addr-line>Toronto, ON</addr-line>
,<country>Canada</country>
,</aff>
<aff id="af28"><label>28</label>
<addr-line>Clinical Genetics</addr-line>
,<institution>Odense University Hospital</institution>
,<addr-line>Odense C</addr-line>
,<country>Denmark</country>
,</aff>
<aff id="af29"><label>29</label>
<addr-line>Clinical Genetics</addr-line>
,<institution>Rigshospital</institution>
,<addr-line>Copenhagen</addr-line>
,<country>Denmark</country>
,</aff>
<aff id="af30"><label>30</label>
<addr-line>Clinical Genetics</addr-line>
,<institution>Aarhus University Hospital</institution>
,<addr-line>Aarhus</addr-line>
,<country>Denmark</country>
,</aff>
<aff id="af31"><label>31</label>
<addr-line>Clinical Genetics</addr-line>
,<institution>Vejle Hospital</institution>
,<addr-line>Vejle</addr-line>
,<country>Denmark</country>
,</aff>
<aff id="af32"><label>32</label>
<addr-line>Section of Genetic Oncology, Department of Laboratory Medicine</addr-line>
,<institution>University and University Hospital of Pisa</institution>
,<addr-line>Pisa</addr-line>
,<country>Italy</country>
,</aff>
<aff id="af33"><label>33</label>
<addr-line>The Susanne Levy Gertner Oncogenetics Unit</addr-line>
,<institution>Sheba Medical Center</institution>
,<addr-line>Tel Hashomer</addr-line>
,<country>Israel</country>
,</aff>
<aff id="af34"><label>34</label>
<addr-line>The Breast cancer Unit</addr-line>
,<institution>Institute of Oncology, Sheba Medical Center</institution>
,<addr-line>Tel-Hashomer</addr-line>
,<country>Israel</country>
,</aff>
<aff id="af35"><label>35</label>
<addr-line>Department of Oncology</addr-line>
,<institution>Lund University Hospital</institution>
,<addr-line>Lund</addr-line>
,<country>Sweden</country>
,</aff>
<aff id="af36"><label>36</label>
<addr-line>Department of Clinical Genetics</addr-line>
and</aff>
<aff id="af37"><label>37</label>
<addr-line>Department of Oncology</addr-line>
,<institution>Karolinska University Hospital</institution>
,<addr-line>S-17176 Stockholm</addr-line>
,<country>Sweden</country>
,</aff>
<aff id="af38"><label>38</label>
<addr-line>Department of Genetics and Pathology</addr-line>
,<institution>Rudbeck Laboratory, Uppsala University</institution>
,<addr-line>S-751 85 Uppsala</addr-line>
,<country>Sweden</country>
,</aff>
<aff id="af39"><label>39</label>
<addr-line>Department of Radiation Sciences</addr-line>
,<institution>Oncology, Umeå University</institution>
,<addr-line>S-901 85 Umeå</addr-line>
,<country>Sweden</country>
,</aff>
<aff id="af40"><label>40</label>
<institution>University of Pennsylvania</institution>
,<addr-line>Philadelphia, PA</addr-line>
,<country>USA</country>
,</aff>
<aff id="af41"><label>41</label>
<addr-line>International Hereditary Cancer Centre, Department of Genetics and Pathology</addr-line>
,<institution>Pomeranian Medical University</institution>
,<addr-line>Szczecin</addr-line>
,<country>Poland</country>
,</aff>
<aff id="af42"><label>42</label>
<addr-line>Human Genetics Group, Human Cancer Genetics Programme</addr-line>
,<institution>Spanish National Cancer Research Centre</institution>
,<addr-line>Madrid</addr-line>
,<country>Spain</country>
,</aff>
<aff id="af43"><label>43</label>
<addr-line>Spanish Network on Rare Diseases (CIBERER)</addr-line>
,</aff>
<aff id="af44"><label>44</label>
<addr-line>Oncology Service</addr-line>
,<institution>Hospital de la Santa Creu i Sant Pau</institution>
,<addr-line>Barcelona</addr-line>
,<country>Spain</country>
,</aff>
<aff id="af45"><label>45</label>
<addr-line>Molecular Diagnostics Laboratory</addr-line>
,<institution>I.R.R.P., National Center for Scientific Research ‘Demokritos’</institution>
,<addr-line>Athens</addr-line>
,<country>Greece</country>
,</aff>
<aff id="af46"><label>46</label>
<addr-line>Oncology unit</addr-line>
,<institution>Hospital clinico Universitario "Lozano Blesa"</institution>
,<addr-line>Zaragoza</addr-line>
,<country>Spain</country>
,</aff>
<aff id="af47"><label>47</label>
<addr-line>Molecular Genetics of Breast Cancer</addr-line>
,<institution>Deutsches Krebsforschungszentrum (DKFZ)</institution>
,<addr-line>Heidelberg</addr-line>
,<country>Germany</country>
,</aff>
<aff id="af48"><label>48</label>
<addr-line>Family Cancer Clinic</addr-line>
and</aff>
<aff id="af49"><label>49</label>
<addr-line>Department of Epidemiology</addr-line>
,<institution>Netherlands Cancer Institute</institution>
,<addr-line>Amsterdam</addr-line>
,<country>The Netherlands</country>
,</aff>
<aff id="af50"><label>50</label>
<addr-line>Department of Medical Oncology</addr-line>
,<institution>Family Cancer Clinic, Erasmus University Medical Center</institution>
,<addr-line>Rotterdam</addr-line>
,<country>The Netherlands</country>
,</aff>
<aff id="af51"><label>51</label>
<addr-line>Department of Human Genetics 849</addr-line>
,<institution>Radboud University Nijmegen Medical Centre</institution>
,<addr-line>Nijmegen</addr-line>
,<country>The Netherlands</country>
,</aff>
<aff id="af52"><label>52</label>
<addr-line>Department of Medical Genetics</addr-line>
,<institution>University Medical Center Utrecht</institution>
,<addr-line>Utrecht</addr-line>
,<country>The Netherlands</country>
,</aff>
<aff id="af53"><label>53</label>
<addr-line>Department of Clinical Genetics</addr-line>
,<institution>Academic Medical Center</institution>
,<addr-line>Amsterdam</addr-line>
,<country>The Netherlands</country>
,</aff>
<aff id="af54"><label>54</label>
<addr-line>Department of Clinical Genetics</addr-line>
,</aff>
<aff id="af55"><label>55</label>
<addr-line>Department of Human Genetics</addr-line>
and</aff>
<aff id="af56"><label>56</label>
<addr-line>Department of Pathology</addr-line>
,<institution>Leiden University Medical Center Leiden</institution>
,<addr-line>Leiden</addr-line>
,<country>The Netherlands</country>
,</aff>
<aff id="af57"><label>57</label>
<addr-line>Department of Clinical Genetics</addr-line>
,<institution>VU Medical Center</institution>
,<addr-line>Amsterdam</addr-line>
,<country>The Netherlands</country>
,</aff>
<aff id="af58"><label>58</label>
<addr-line>Department of Clinical Genetics and GROM, School for Oncology</addr-line>
and</aff>
<aff id="af59"><label>59</label>
<addr-line>Developmental Biology</addr-line>
,<institution>MUMC</institution>
,<addr-line>Maastricht</addr-line>
,<country>The Netherlands</country>
,</aff>
<aff id="af60"><label>60</label>
<addr-line>Genetic Medicine</addr-line>
,<institution>Manchester Academic Health Sciences Centre, Central Manchester University Hospitals NHS Foundation Trust</institution>
,<addr-line>Manchester</addr-line>
,<country>UK</country>
,</aff>
<aff id="af61"><label>61</label>
<addr-line>Oncogenetics Team</addr-line>
,<institution>The Institute of Cancer Research and Royal Marsden NHS Foundation Trust</institution>
,<addr-line>Surrey</addr-line>
,<country>UK</country>
,</aff>
<aff id="af62"><label>62</label>
<addr-line>Clinical Genetics</addr-line>
,<institution>Guy's and St. Thomas’ NHS Foundation Trust</institution>
,<addr-line>London</addr-line>
,<country>UK</country>
,</aff>
<aff id="af63"><label>63</label>
<institution>Yorkshire Regional Genetics Service</institution>
,<addr-line>Leeds</addr-line>
,<country>UK</country>
,</aff>
<aff id="af64"><label>64</label>
<addr-line>Ferguson-Smith Centre for Clinical Genetics</addr-line>
,<institution>Yorkhill Hospitals</institution>
,<addr-line>Glasgow</addr-line>
,<country>UK</country>
,</aff>
<aff id="af65"><label>65</label>
<addr-line>Wessex Clinical Genetics Service</addr-line>
<institution>, Princess Anne Hospital</institution>
,<addr-line>Southampton</addr-line>
,<country>UK</country>
,</aff>
<aff id="af66"><label>66</label>
<addr-line>West Midlands Regional Genetics Service</addr-line>
,<institution>Birmingham Women's Hospital Healthcare NHS Trust</institution>
,<addr-line>Edgbaston, Birmingham</addr-line>
,<country>UK</country>
,</aff>
<aff id="af67"><label>67</label>
<addr-line>Sheffield Clinical Genetics Service</addr-line>
,<institution>Sheffield Children's Hospital</institution>
,<addr-line>Sheffield</addr-line>
,<country>UK</country>
,</aff>
<aff id="af68"><label>68</label>
<institution>Institute of Human Genetics, Centre for Life, Newcastle Upon Tyne Hospitals NHS Trust</institution>
,<addr-line>Newcastle upon Tyne</addr-line>
,<country>UK</country>
,</aff>
<aff id="af69"><label>69</label>
<addr-line>Department of Clinical Genetics, East Anglian Regional Genetics Service</addr-line>
,<institution>Addenbrookes Hospital</institution>
,<addr-line>Cambridge</addr-line>
,<country>UK</country>
,</aff>
<aff id="af70"><label>70</label>
<addr-line>Academic Unit of Clinical and Molecular Oncology</addr-line>
,<institution>Trinity College Dublin and St James's Hospital</institution>
,<addr-line>Dublin</addr-line>
,<country>Eire</country>
,</aff>
<aff id="af71"><label>71</label>
<addr-line>North of Scotland Regional Genetics Service</addr-line>
,<institution>NHS Grampian & University of Aberdeen</institution>
,<addr-line>Foresterhill, Aberdeen</addr-line>
,<country>UK</country>
,</aff>
<aff id="af72"><label>72</label>
<addr-line>Department of Pathology and Laboratory Medicine</addr-line>
,<institution>University of Kansas Medical Center</institution>
,<addr-line>Kansas City</addr-line>
,<country>USA</country>
,</aff>
<aff id="af73"><label>73</label>
<addr-line>Service de Génétique Oncologique</addr-line>
and</aff>
<aff id="af74"><label>74</label>
<addr-line>Unité INSERM U830</addr-line>
,<institution>Institut Curie</institution>
,<addr-line>Paris</addr-line>
,<country>France</country>
,</aff>
<aff id="af75"><label>75</label>
<addr-line>Faculté de Médecine</addr-line>
,<institution>Université Paris Descartes</institution>
,<addr-line>Paris</addr-line>
,<country>France</country>
,</aff>
<aff id="af76"><label>76</label>
<addr-line>CNRS UMR5558</addr-line>
,<institution>Université Lyon 1</institution>
,<addr-line>Lyon</addr-line>
,<country>France</country>
,</aff>
<aff id="af77"><label>77</label>
<addr-line>Unité de Prévention et d'Epidémiologie Génétique</addr-line>
,<institution>Centre Léon Bérard</institution>
,<addr-line>Lyon</addr-line>
,<country>France</country>
,</aff>
<aff id="af78"><label>78</label>
<addr-line>Department of Genetics</addr-line>
,<institution>Centre Hospitalier Universitaire de Grenoble</institution>
,<addr-line>Grenoble</addr-line>
,<country>France</country>
,</aff>
<aff id="af79"><label>79</label>
<institution>Institut Albert Bonniot, Université de Grenoble</institution>
,<addr-line>Grenoble</addr-line>
,<country>France</country>
,</aff>
<aff id="af80"><label>80</label>
<addr-line>Centre de Génétique</addr-line>
,<institution>Centre Hospitalier Universitaire de Dijon</institution>
,<country>France</country>
,</aff>
<aff id="af81"><label>81</label>
<institution>Centre de Lutte Contre le Cancer Georges François Leclerc</institution>
,<addr-line>Dijon</addr-line>
,<country>France</country>
,</aff>
<aff id="af82"><label>82</label>
<addr-line>Laboratoire de Génétique Médicale</addr-line>
,<institution>Nancy Université, Centre Hospitalier Régional et Universitaire</institution>
,<addr-line>Vandoeuvre-les-Nancy</addr-line>
,<country>France</country>
,</aff>
<aff id="af83"><label>83</label>
<addr-line>Service de Génétique Clinique Chromosomique et Moléculaire</addr-line>
,<institution>Centre Hospitalier Universitaire de St Etienne</institution>
,<addr-line>St Etienne</addr-line>
,<country>France</country>
,</aff>
<aff id="af84"><label>84</label>
<addr-line>Oncogénétique Clinique</addr-line>
and</aff>
<aff id="af85"><label>85</label>
<addr-line>Laboratoire d'Oncogénétique</addr-line>
,<institution>Hôpital René Huguenin/Institut Curie</institution>
,<addr-line>Saint-Cloud</addr-line>
,<country>France</country>
,</aff>
<aff id="af86"><label>86</label>
<addr-line>Unité d'Oncogénétique</addr-line>
,<institution>CHU Arnaud de Villeneuve</institution>
,<addr-line>Montpellier</addr-line>
,<country>France</country>
,</aff>
<aff id="af87"><label>87</label>
<addr-line>INSERM 896</addr-line>
,<institution>CRCM Val d'Aurelle</institution>
,<addr-line>Montpellier</addr-line>
,<country>France</country>
,</aff>
<aff id="af88"><label>88</label>
<addr-line>Unité d'Oncogénétique</addr-line>
,<institution>CRLCC Val d'Aurelle</institution>
,<addr-line>Montpellier</addr-line>
,<country>France</country>
,</aff>
<aff id="af89"><label>89</label>
<institution>Centre Antoine Lacassagne</institution>
,<addr-line>Nice</addr-line>
,<country>France</country>
,</aff>
<aff id="af90"><label>90</label>
<institution>The University of Melbourne</institution>
,<addr-line>Melbourne</addr-line>
,<country>Australia</country>
,</aff>
<aff id="af91"><label>91</label>
<addr-line>Women's Cancer Program, Department of Medical Oncology</addr-line>
,<institution>Fox Chase Cancer Center</institution>
,<addr-line>Philadelphia, PA</addr-line>
,<country>USA</country>
,</aff>
<aff id="af92"><label>92</label>
<institution>Columbia University New York</institution>
,<addr-line>New York, NY</addr-line>
,<country>USA</country>
,</aff>
<aff id="af93"><label>93</label>
<institution>Cancer Prevention Institute of California (formerly the Northern California Cancer Center)</institution>
,<addr-line>Fremont, CA</addr-line>
,<country>USA</country>
,</aff>
<aff id="af94"><label>94</label>
<addr-line>Stanford Cancer Center</addr-line>
,<institution>Stanford University School of Medicine</institution>
,<addr-line>Stanford, CA</addr-line>
,<country>USA</country>
,</aff>
<aff id="af95"><label>95</label>
<addr-line>Huntsman Cancer Institute</addr-line>
,<institution>University of Utah Health Sciences Centre</institution>
,<addr-line>Salt Lake City, UT</addr-line>
,<country>USA</country>
,</aff>
<aff id="af96"><label>96</label>
<institution>Dana-Farber Cancer Institute</institution>
,<addr-line>Boston, MA</addr-line>
,<country>USA</country>
,</aff>
<aff id="af97"><label>97</label>
<addr-line>Department of Dermatology</addr-line>
,<institution>University of Utah</institution>
,<addr-line>Salt Lake City, UT</addr-line>
,<country>USA</country>
,</aff>
<aff id="af98"><label>98</label>
<addr-line>Department of Obstetrics/Gynaecology</addr-line>
,<institution>Medical University of Vienna</institution>
,<addr-line>Vienna</addr-line>
,<country>Austria</country>
,</aff>
<aff id="af99"><label>99</label>
<addr-line>Genomic Medicine, Department of Clinical Biochemistry</addr-line>
and</aff>
<aff id="af100"><label>100</label>
<addr-line>Department of Oncology</addr-line>
,<institution>Rigshospitalet</institution>
,<institution>Copenhagen University Hospital</institution>
,<addr-line>Allerød</addr-line>
,<country>Denmark</country>
,</aff>
<aff id="af101"><label>101</label>
<addr-line>Laboratory of Cell Biology, Department of Pathology</addr-line>
,<institution>Landspitali-University Hospital</institution>
,<addr-line>Tromsø</addr-line>
,<country>Norway,</country>
</aff>
<aff id="af102"><label>102</label>
<addr-line>Faculty of Medicine</addr-line>
,<institution>University of Iceland</institution>
,<addr-line>Reykjavik</addr-line>
,<country>Iceland</country>
,</aff>
<aff id="af103"><label>103</label>
<addr-line>Clinical Genetics Service, Department of Medicine</addr-line>
,<institution>Memorial Sloan-Kettering Cancer Center</institution>
,<addr-line>New York, NY</addr-line>
,<country>USA</country>
,</aff>
<aff id="af104"><label>104</label>
<addr-line>GOG Statistical and Data Center</addr-line>
and</aff>
<aff id="af105"><label>105</label>
<addr-line>Department of Cancer Prevention and Control</addr-line>
,<institution>Roswell Park Cancer Institute</institution>
,<addr-line>Buffalo, NY</addr-line>
14263,<country>USA</country>
,</aff>
<aff id="af106"><label>106</label>
<institution>Evanston Northwestern Healthcare</institution>
,<addr-line>Evanston, IL</addr-line>
,<country>USA</country>
,</aff>
<aff id="af107"><label>107</label>
<institution>Maine Medical Center</institution>
,<addr-line>Scarborough, ME</addr-line>
,<country>USA</country>
,</aff>
<aff id="af108"><label>108</label>
<institution>University of North Carolina</institution>
,<addr-line>Chapel Hill, NC</addr-line>
,<country>USA</country>
,</aff>
<aff id="af109"><label>109</label>
<institution>New York University School of Medicine</institution>
,<addr-line>New York, NY</addr-line>
,<country>USA</country>
,</aff>
<aff id="af110"><label>110</label>
<institution>St. Elizabeth Medical Center</institution>
,<addr-line>Edgewood, KY</addr-line>
,<country>USA</country>
,</aff>
<aff id="af111"><label>111</label>
<institution>Yale University School of Medicine</institution>
,<addr-line>New Haven, CT</addr-line>
,<country>USA</country>
,</aff>
<aff id="af112"><label>112</label>
<addr-line>Comprehensive Cancer Center, Department of Molecular Virology, Immunology and Medical Genetics</addr-line>
,<institution>The Ohio State University</institution>
,<addr-line>Columbus, OH</addr-line>
,<country>USA</country>
,</aff>
<aff id="af113"><label>113</label>
<addr-line>Immunology and Molecular Oncology Unit</addr-line>
,<institution>Istituto Oncologico Veneto IOV - IRCCS</institution>
,<addr-line>Padua</addr-line>
,<country>Italy</country>
,</aff>
<aff id="af114"><label>114</label>
<institution>N.N. Petrov Institute of Oncology</institution>
,<addr-line>St.-Petersburg</addr-line>
, 197758,<country>Russia</country>
,</aff>
<aff id="af115"><label>115</label>
<addr-line>Department of Molecular and Regenerative Medicine</addr-line>
,<institution>Vilnius university hospital Santariskiu Clinics</institution>
,<institution>Hematology</institution>
,<institution>Oncology and Transfusion Medicine Center</institution>
,<addr-line>Vilnius</addr-line>
,<country>Lithuania</country>
,</aff>
<aff id="af116"><label>116</label>
<institution>State Research Institute Inovative medicine center</institution>
,<addr-line>Vilnius</addr-line>
,<country>Lithuania</country>
,</aff>
<aff id="af117"><label>117</label>
<addr-line>Hereditary Cancer Program</addr-line>
,<institution>Catalan Institute of Oncology</institution>
,<addr-line>Barcelona</addr-line>
,<country>Spain</country>
,</aff>
<aff id="af118"><label>118</label>
<institution>Women's Cancer Research Institute at the Samuel Oschin Comprehensive Cancer Institute</institution>
,<institution>Cedars-Sinai Medical Center</institution>
,<addr-line>Los Angeles, CA</addr-line>
,<country>USA</country>
,</aff>
<aff id="af119"><label>119</label>
<addr-line>Department of Molecular Genetics</addr-line>
,<institution>National Institute of Oncology</institution>
,<addr-line>Budapest</addr-line>
,<country>Hungary</country>
,</aff>
<aff id="af120"><label>120</label>
<addr-line>Cancer Research Initiatives Foundation</addr-line>
,<institution>Sime Darby Medical Centre</institution>
,<addr-line>Subang Jaya</addr-line>
,<country>Malaysia</country>
,</aff>
<aff id="af121"><label>121</label>
<institution>University Malaya Cancer Research Institute</institution>
,<institution>University Malaya</institution>
,<addr-line>Kuala Lumpur</addr-line>
,<country>Malaysia</country>
,</aff>
<aff id="af122"><label>122</label>
<addr-line>UCLA Cancer Genetics Program</addr-line>
,<institution>CLA Jonsson Comp Cancer Center</institution>
,<addr-line>Santa Monica, CA</addr-line>
,<country>USA</country>
,</aff>
<aff id="af123"><label>123</label>
<addr-line>UCSF Cancer Risk Program</addr-line>
,<institution>University of California</institution>
,<addr-line>San Francisco, CA</addr-line>
,<country>USA</country>
,</aff>
<aff id="af124"><label>124</label>
<addr-line>UCSF Department of Medicine</addr-line>
,</aff>
<aff id="af125"><label>125</label>
<addr-line>Department of Epidemiology</addr-line>
and</aff>
<aff id="af126"><label>126</label>
<addr-line>Department of Biostatistics</addr-line>
,<institution>University of California</institution>
,<addr-line>San Francisco, CA</addr-line>
,<country>USA</country>
,</aff>
<aff id="af127"><label>127</label>
<addr-line>Department of Genetics</addr-line>
,<institution>University of Pretoria</institution>
,<addr-line>Pretoria</addr-line>
,<country>South Africa</country>
,</aff>
<aff id="af128"><label>128</label>
<addr-line>Oncogenetics Laboratory</addr-line>
,<institution>University Hospital Vall d'Hebron</institution>
,<addr-line>Barcelona</addr-line>
,<country>Spain</country>
,</aff>
<aff id="af129"><label>129</label>
<institution>Vall d'Hebron Institute of Oncology (VHIO)</institution>
,<addr-line>Barcelona</addr-line>
,<country>Spain</country>
,</aff>
<aff id="af130"><label>130</label>
<addr-line>Centre of Familial Breast and Ovarian Cancer, Department of Gynaecology and Obstetrics</addr-line>
and</aff>
<aff id="af131"><label>131</label>
<addr-line>Centre for Integrated Oncology (CIO)</addr-line>
,<institution>University hospital of Cologne</institution>
,<addr-line>Cologne</addr-line>
,<country>Germany</country>
,</aff>
<aff id="af132"><label>132</label>
<addr-line>Institute for Medical Informatics, Statistics and Epidemiology</addr-line>
,<institution>University of Leipzig</institution>
,<addr-line>Leipzig</addr-line>
,<country>Germany</country>
,</aff>
<aff id="af133"><label>133</label>
<addr-line>Department of Gynaecology and Obstetrics, Division of Tumor Genetics, Klinikum rechts der Isar</addr-line>
,<institution>Technical University Munich</institution>
,<addr-line>Munich</addr-line>
,<country>Germany</country>
,</aff>
<aff id="af134"><label>134</label>
<addr-line>Department of Gynaecology and Obstetrics</addr-line>
,<institution>Ludwig-Maximillians University Munich</institution>
,<addr-line>Munich</addr-line>
,<country>Germany</country>
,</aff>
<aff id="af135"><label>135</label>
<institution>Institute of Human Genetics</institution>
,<addr-line>Campus Virchov Klinikum, Charite Berlin</addr-line>
,<country>Germany</country>
,</aff>
<aff id="af136"><label>136</label>
<addr-line>Department of Gynaecology and Obstetrics</addr-line>
,<institution>University Hospital Carl Gustav Carus, Technical University Dresden</institution>
,<addr-line>Dresden</addr-line>
,<country>Germany</country>
,</aff>
<aff id="af137"><label>137</label>
<addr-line>Department of Gynaecology and Obstetrics</addr-line>
,<institution>University Hospital Ulm</institution>
,<addr-line>Ulm</addr-line>
,<country>Germany</country>
,</aff>
<aff id="af138"><label>138</label>
<addr-line>Department of Gynaecology and Obstetrics</addr-line>
,<institution>University Hospital Düsseldorf, Heinrich-Heine University Düsseldorf</institution>
,<addr-line>Düsseldorf</addr-line>
,<country>Germany</country>
,</aff>
<aff id="af139"><label>139</label>
<addr-line>Department of Gynaecology and Obstetrics</addr-line>
,<institution>University Hospital of Schleswig-Holstein, Campus Kiel, Christian-Albrechts University Kiel</institution>
,<addr-line>Kiel</addr-line>
,<country>Germany</country>
,</aff>
<aff id="af140"><label>140</label>
<institution>Institute of Cell and Molecular Pathology, Hannover Medical School</institution>
,<addr-line>Hannover</addr-line>
,<country>Germany</country>
,</aff>
<aff id="af141"><label>141</label>
<addr-line>Centre of Familial Breast and Ovarian Cancer, Department of Medical Genetics</addr-line>
,<institution>Institute of Human Genetics, University Würzburg</institution>
,<addr-line>Würzburg</addr-line>
,<country>Germany</country>
,</aff>
<aff id="af142"><label>142</label>
<addr-line>Molecular Oncology Laboratory</addr-line>
,<institution>Hospital Clinico San Carlos</institution>
,<addr-line>Madrid</addr-line>
,<country>Spain</country>
,</aff>
<aff id="af143"><label>143</label>
<addr-line>Department of Obstetrics and Gynecology</addr-line>
and</aff>
<aff id="af144"><label>144</label>
<addr-line>Department of Clinical Genetics</addr-line>
,<institution>Helsinki University Central Hospital</institution>
,<addr-line>Helsinki</addr-line>
,<country>Finland</country>
,</aff>
<aff id="af145"><label>145</label>
<addr-line>Unité de recherche en santé des populations</addr-line>
,<institution>Centre des maladies du sein Deschênes-Fabia, Centre de recherche FRSQ du Centre hospitalier affilié universitaire de Québec</institution>
,<addr-line>Québec, QC</addr-line>
,<country>Canada</country>
,</aff>
<aff id="af146"><label>146</label>
<addr-line>Program in Cancer Genetics, Departments of Human Genetics and Oncology</addr-line>
,<institution>McGill University</institution>
,<addr-line>Montreal, QC</addr-line>
,<country>Canada</country>
,</aff>
<aff id="af147"><label>147</label>
<institution>Lady Davis Institute, Segal Cancer Centre, Jewish General Hospital</institution>
,<addr-line>Montreal, QC</addr-line>
,<country>Canada</country>
,</aff>
<aff id="af148"><label>148</label>
<addr-line>Department of Population Sciences</addr-line>
,<institution>Beckman Research Institute of the City of Hope</institution>
, Duarte,<addr-line>CA</addr-line>
,<country>USA</country>
,</aff>
<aff id="af149"><label>149</label>
<addr-line>Department of Health Sciences Research</addr-line>
,<institution>Mayo Clinic</institution>
,<addr-line>Rochester, MN</addr-line>
,<country>USA</country>
and</aff>
<aff id="af150"><label>150</label>
<addr-line>Department of Laboratory Medicine and Pathology</addr-line>
,<institution>Mayo Clinic</institution>
,<addr-line>Rochester, MN</addr-line>
,<country>USA</country>
</aff>
<author-notes><corresp id="cor1"><sup>*</sup>
To whom correspondence should be addressed at: Strangeways Research Laboratory, University of Cambridge, Worts Causeway, Cambridge CB1 8RN, UK. Tel: +44 1223 740163; Fax: +44 1223 740159; Email: <email>antonis@srl.cam.ac.uk</email>
</corresp>
<fn id="AN1"><label>†</label>
<p>Joint senior authors.</p>
</fn>
</author-notes>
<pub-date pub-type="ppub"><day>15</day>
<month>8</month>
<year>2011</year>
</pub-date>
<pub-date pub-type="epub"><day>18</day>
<month>5</month>
<year>2011</year>
</pub-date>
<volume>20</volume>
<issue>16</issue>
<fpage>3304</fpage>
<lpage>3321</lpage>
<history><date date-type="received"><day>24</day>
<month>3</month>
<year>2011</year>
</date>
<date date-type="rev-recd"><day>9</day>
<month>5</month>
<year>2011</year>
</date>
<date date-type="accepted"><day>16</day>
<month>5</month>
<year>2011</year>
</date>
</history>
<permissions><copyright-statement>© The Author 2011. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com</copyright-statement>
<copyright-year>2011</copyright-year>
</permissions>
<self-uri content-type="pdf" xlink:type="simple" xlink:href="ddr226.pdf"></self-uri>
<abstract><p>Two single nucleotide polymorphisms (SNPs) at 6q25.1, near the <italic>ESR1</italic>
gene, have been implicated in the susceptibility to breast cancer for Asian (rs2046210) and European women (rs9397435). A genome-wide association study in Europeans identified two further breast cancer susceptibility variants: rs11249433 at 1p11.2 and rs999737 in <italic>RAD51L1</italic>
at 14q24.1. Although previously identified breast cancer susceptibility variants have been shown to be associated with breast cancer risk for <italic>BRCA1</italic>
and <italic>BRCA2</italic>
mutation carriers, the involvement of these SNPs to breast cancer susceptibility in mutation carriers is currently unknown. To address this, we genotyped these SNPs in <italic>BRCA1</italic>
and <italic>BRCA2</italic>
mutation carriers from 42 studies from the Consortium of Investigators of Modifiers of <italic>BRCA1/2</italic>
<italic>.</italic>
In the analysis of 14 123 <italic>BRCA1</italic>
and 8053 <italic>BRCA2</italic>
mutation carriers of European ancestry, the 6q25.1 SNPs (<italic>r</italic>
<sup>2</sup>
= 0.14) were independently associated with the risk of breast cancer for <italic>BRCA1</italic>
mutation carriers [hazard ratio (HR) = 1.17, 95% confidence interval (CI): 1.11–1.23, <italic>P</italic>
-trend = 4.5 × 10<sup>−9</sup>
for rs2046210; HR = 1.28, 95% CI: 1.18–1.40, <italic>P</italic>
-trend = 1.3 × 10<sup>−8</sup>
for rs9397435], but only rs9397435 was associated with the risk for <italic>BRCA2</italic>
carriers (HR = 1.14, 95% CI: 1.01–1.28, <italic>P</italic>
-trend = 0.031). SNP rs11249433 (1p11.2) was associated with the risk of breast cancer for <italic>BRCA2</italic>
mutation carriers (HR = 1.09, 95% CI: 1.02–1.17, <italic>P</italic>
-trend = 0.015), but was not associated with breast cancer risk for <italic>BRCA1</italic>
mutation carriers (HR = 0.97, 95% CI: 0.92–1.02, <italic>P</italic>
-trend = 0.20). SNP rs999737 (<italic>RAD51L1</italic>
) was not associated with breast cancer risk for either <italic>BRCA1</italic>
or <italic>BRCA2</italic>
mutation carriers (<italic>P</italic>
-trend = 0.27 and 0.30, respectively). The identification of SNPs at 6q25.1 associated with breast cancer risk for <italic>BRCA1</italic>
mutation carriers will lead to a better understanding of the biology of tumour development in these women.</p>
</abstract>
</article-meta>
</front>
</pmc>
</record>
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