Serveur d'exploration sur les relations entre la France et l'Australie

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Impact and Effectiveness of the Quadrivalent Human Papillomavirus Vaccine: A Systematic Review of 10 Years of Real-world Experience

Identifieur interne : 000656 ( Pmc/Curation ); précédent : 000655; suivant : 000657

Impact and Effectiveness of the Quadrivalent Human Papillomavirus Vaccine: A Systematic Review of 10 Years of Real-world Experience

Auteurs : Suzanne M. Garland [Australie] ; Susanne K. Kjaer [Danemark] ; Nubia Mu Oz ; Stan L. Block ; Darron R. Brown ; Mark J. Dinubile [États-Unis] ; Brianna R. Lindsay [États-Unis] ; Barbara J. Kuter [États-Unis] ; Gonzalo Perez [États-Unis, Colombie] ; Geraldine Dominiak-Felden [France] ; Alfred J. Saah [États-Unis] ; Rosybel Drury [France] ; Rituparna Das [États-Unis] ; Christine Velicer [États-Unis]

Source :

RBID : PMC:4967609

Abstract

This systematic review assessed the global impact and effectiveness of quadrivalent human papillomavirus (HPV) vaccination on HPV infection and disease in real-world settings over a decade of use. Substantial reductions in HPV 6/11/16/18 infection, anogenital warts, and cervical lesions have been achieved.


Url:
DOI: 10.1093/cid/ciw354
PubMed: 27230391
PubMed Central: 4967609

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PMC:4967609

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Darron R. Brown
<affiliation>
<nlm:aff id="af5">
<institution>Indiana University School of Medicine</institution>
, Indianapolis</nlm:aff>
<wicri:noCountry code="subfield">Indianapolis</wicri:noCountry>
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Le document en format XML

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<p>This systematic review assessed the global impact and effectiveness of quadrivalent human papillomavirus (HPV) vaccination on HPV infection and disease in real-world settings over a decade of use. Substantial reductions in HPV 6/11/16/18 infection, anogenital warts, and cervical lesions have been achieved.</p>
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</TEI>
<pmc article-type="review-article">
<pmc-dir>properties open_access</pmc-dir>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">Clin Infect Dis</journal-id>
<journal-id journal-id-type="iso-abbrev">Clin. Infect. Dis</journal-id>
<journal-id journal-id-type="publisher-id">cid</journal-id>
<journal-id journal-id-type="hwp">cid</journal-id>
<journal-title-group>
<journal-title>Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America</journal-title>
</journal-title-group>
<issn pub-type="ppub">1058-4838</issn>
<issn pub-type="epub">1537-6591</issn>
<publisher>
<publisher-name>Oxford University Press</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">27230391</article-id>
<article-id pub-id-type="pmc">4967609</article-id>
<article-id pub-id-type="doi">10.1093/cid/ciw354</article-id>
<article-id pub-id-type="publisher-id">ciw354</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Review Articles</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Impact and Effectiveness of the Quadrivalent Human Papillomavirus Vaccine: A Systematic Review of 10 Years of Real-world Experience</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Garland</surname>
<given-names>Suzanne M.</given-names>
</name>
<xref ref-type="aff" rid="af1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Kjaer</surname>
<given-names>Susanne K.</given-names>
</name>
<xref ref-type="aff" rid="af2">2</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Muñoz</surname>
<given-names>Nubia</given-names>
</name>
<xref ref-type="aff" rid="af3">3</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Block</surname>
<given-names>Stan L.</given-names>
</name>
<xref ref-type="aff" rid="af4">4</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Brown</surname>
<given-names>Darron R.</given-names>
</name>
<xref ref-type="aff" rid="af5">5</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>DiNubile</surname>
<given-names>Mark J.</given-names>
</name>
<xref ref-type="aff" rid="af6">6</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Lindsay</surname>
<given-names>Brianna R.</given-names>
</name>
<xref ref-type="aff" rid="af6">6</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Kuter</surname>
<given-names>Barbara J.</given-names>
</name>
<xref ref-type="aff" rid="af6">6</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Perez</surname>
<given-names>Gonzalo</given-names>
</name>
<xref ref-type="aff" rid="af6">6</xref>
<xref ref-type="aff" rid="af7">7</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Dominiak-Felden</surname>
<given-names>Geraldine</given-names>
</name>
<xref ref-type="aff" rid="af8">8</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Saah</surname>
<given-names>Alfred J.</given-names>
</name>
<xref ref-type="aff" rid="af6">6</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Drury</surname>
<given-names>Rosybel</given-names>
</name>
<xref ref-type="aff" rid="af8">8</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Das</surname>
<given-names>Rituparna</given-names>
</name>
<xref ref-type="aff" rid="af6">6</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Velicer</surname>
<given-names>Christine</given-names>
</name>
<xref ref-type="aff" rid="af6">6</xref>
</contrib>
<aff id="af1">
<label>1</label>
<institution>Royal Women's Hospital, University of Melbourne, Murdoch Childrens Research Institute</institution>
,
<addr-line>Victoria</addr-line>
,
<country>Australia</country>
</aff>
<aff id="af2">
<label>2</label>
<addr-line>Danish Cancer Society Research Center and Department of Gynecology</addr-line>
,
<institution>Rigshospitalet, University of Copenhagen</institution>
,
<country>Denmark</country>
</aff>
<aff id="af3">
<label>3</label>
<institution>Colombian National Institute of Cancer</institution>
,
<addr-line>Bogota</addr-line>
</aff>
<aff id="af4">
<label>4</label>
<institution>Kentucky Pediatric and Adult Research</institution>
,
<addr-line>Bardstown</addr-line>
</aff>
<aff id="af5">
<label>5</label>
<institution>Indiana University School of Medicine</institution>
, Indianapolis</aff>
<aff id="af6">
<label>6</label>
<institution>Merck & Co, Inc</institution>
,
<addr-line>Kenilworth, New Jersey</addr-line>
</aff>
<aff id="af7">
<label>7</label>
<institution>Universidad del Rosario</institution>
,
<addr-line>Bogota</addr-line>
,
<country>Colombia</country>
</aff>
<aff id="af8">
<label>8</label>
<institution>Sanofi Pasteur MSD</institution>
,
<addr-line>Lyon</addr-line>
,
<country>France</country>
</aff>
</contrib-group>
<author-notes>
<corresp>Correspondence: S. M. Garland, Royal Women's Hospital, Department of Clinical Microbiology and Infectious Diseases, Locked Bag 300, Parkville, Victoria, Australia (
<email>suzanne.garland@thewomens.org.au</email>
).</corresp>
</author-notes>
<pub-date pub-type="ppub">
<day>15</day>
<month>8</month>
<year>2016</year>
</pub-date>
<pub-date pub-type="epub">
<day>26</day>
<month>5</month>
<year>2016</year>
</pub-date>
<pub-date pub-type="pmc-release">
<day>26</day>
<month>5</month>
<year>2016</year>
</pub-date>
<pmc-comment> PMC Release delay is 0 months and 0 days and was based on the . </pmc-comment>
<volume>63</volume>
<issue>4</issue>
<fpage>519</fpage>
<lpage>527</lpage>
<history>
<date date-type="received">
<day>29</day>
<month>3</month>
<year>2016</year>
</date>
<date date-type="accepted">
<day>18</day>
<month>5</month>
<year>2016</year>
</date>
</history>
<permissions>
<copyright-statement>© The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America.</copyright-statement>
<copyright-year>2016</copyright-year>
<license license-type="creative-commons" xlink:href="http://creativecommons.org/licenses/by/4.0/">
<license-p>This is an Open Access article distributed under the terms of the Creative Commons Attribution License (
<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/4.0/">http://creativecommons.org/licenses/by/4.0/</ext-link>
), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
</license>
</permissions>
<self-uri content-type="pdf" xlink:href="ciw354.pdf"></self-uri>
<abstract abstract-type="precis">
<p>This systematic review assessed the global impact and effectiveness of quadrivalent human papillomavirus (HPV) vaccination on HPV infection and disease in real-world settings over a decade of use. Substantial reductions in HPV 6/11/16/18 infection, anogenital warts, and cervical lesions have been achieved.</p>
</abstract>
<abstract>
<p>Prophylactic human papillomavirus (HPV) vaccination programs constitute major public health initiatives worldwide. We assessed the global effect of quadrivalent HPV (4vHPV) vaccination on HPV infection and disease. PubMed and Embase were systematically searched for peer-reviewed articles from January 2007 through February 2016 to identify observational studies reporting the impact or effectiveness of 4vHPV vaccination on infection, anogenital warts, and cervical cancer or precancerous lesions. Over the last decade, the impact of HPV vaccination in real-world settings has become increasingly evident, especially among girls vaccinated before HPV exposure in countries with high vaccine uptake. Maximal reductions of approximately 90% for HPV 6/11/16/18 infection, approximately 90% for genital warts, approximately 45% for low-grade cytological cervical abnormalities, and approximately 85% for high-grade histologically proven cervical abnormalities have been reported. The full public health potential of HPV vaccination is not yet realized. HPV-related disease remains a significant source of morbidity and mortality in developing and developed nations, underscoring the need for HPV vaccination programs with high population coverage.</p>
</abstract>
<kwd-group>
<kwd>HPV vaccination</kwd>
<kwd>cervical cancer</kwd>
<kwd>CIN</kwd>
<kwd>genital warts</kwd>
<kwd>Gardasil/Silgard</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>

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