FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium
Identifieur interne : 000085 ( Pmc/Curation ); précédent : 000084; suivant : 000086FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium
Auteurs : D. Agarwal [Espagne, États-Unis] ; S. Pineda [Espagne] ; K. Michailidou [Royaume-Uni] ; J. Herranz [Espagne] ; G. Pita [Espagne] ; L T Moreno [Espagne] ; M R Alonso [Espagne] ; J. Dennis [Royaume-Uni] ; Q. Wang [Royaume-Uni] ; M K Bolla [Royaume-Uni] ; K B Meyer [Royaume-Uni] ; P. Menéndez-Rodríguez [Espagne] ; D. Hardisson [Espagne] ; M. Mendiola [Espagne] ; A. González-Neira [Espagne] ; A. Lindblom [Suède] ; S. Margolin [Suède] ; A. Swerdlow [Royaume-Uni] ; A. Ashworth [Royaume-Uni] ; N. Orr [Royaume-Uni] ; M. Jones [Royaume-Uni] ; K. Matsuo [Japon] ; H. Ito [Japon] ; H. Iwata [Japon] ; N. Kondo [Japon] ; M. Hartman [Singapour] ; M. Hui [Singapour] ; W Y Lim [Singapour] ; P. T-C Iau [Singapour] ; E. Sawyer [Royaume-Uni] ; I. Tomlinson [Royaume-Uni] ; M. Kerin [Royaume-Uni] ; N. Miller [Royaume-Uni] ; D. Kang [Corée du Sud] ; J-Y Choi [Corée du Sud] ; S K Park [Corée du Sud] ; D-Y Noh [Corée du Sud] ; J L Hopper [Australie] ; D F Schmidt [Australie] ; E. Makalic [Australie] ; M C Southey [Australie] ; S H Teo [Malaisie] ; C H Yip [Malaisie] ; K. Sivanandan [Malaisie] ; W-T Tay [Singapour] ; H. Brauch [Allemagne] ; T. Brüning [Allemagne] ; U. Hamann [Allemagne] ; A M Dunning [Royaume-Uni] ; M. Shah [Royaume-Uni] ; I L Andrulis [Canada] ; J A Knight [Canada] ; G. Glendon [Canada] ; S. Tchatchou [Canada] ; M K Schmidt [Pays-Bas] ; A. Broeks [Pays-Bas] ; E H Rosenberg [Pays-Bas] ; L J Van'T Veer [Pays-Bas] ; P A Fasching [Allemagne, États-Unis] ; S P Renner [Allemagne] ; A B Ekici [Allemagne] ; M W Beckmann [Allemagne] ; C-Y Shen [Taïwan] ; C-N Hsiung [Taïwan] ; J-C Yu [Taïwan] ; M-F Hou [Taïwan] ; W. Blot ; Q. Cai ; A H Wu [États-Unis] ; C-C Tseng [États-Unis] ; D. Van Den Berg [États-Unis] ; D O Stram [États-Unis] ; A. Cox [Royaume-Uni] ; I W Brock [Royaume-Uni] ; M W R. Reed [Royaume-Uni] ; K. Muir [Royaume-Uni] ; A. Lophatananon [Royaume-Uni] ; S. Stewart-Brown [Royaume-Uni] ; P. Siriwanarangsan [Thaïlande] ; W. Zheng [États-Unis] ; S. Deming-Halverson [États-Unis] ; M J Shrubsole [États-Unis] ; J. Long [États-Unis] ; X-O Shu [États-Unis] ; W. Lu [République populaire de Chine] ; Y-T Gao [République populaire de Chine] ; B. Zhang [États-Unis] ; P. Radice [Italie] ; P. Peterlongo [Italie] ; S. Manoukian [Italie] ; F. Mariette [Italie] ; S. Sangrajrang [Thaïlande] ; J. Mckay [France] ; F J Couch [États-Unis] ; A E Toland [États-Unis] ; D. Yannoukakos [Grèce] ; O. Fletcher [Royaume-Uni] ; N. Johnson [Royaume-Uni] ; I Dos Santos Silva [Royaume-Uni] ; J. Peto [Royaume-Uni] ; F. Marme [Allemagne] ; B. Burwinkel [Allemagne] ; P. Guénel [France] ; T. Truong [France] ; M. Sanchez [France] ; C. Mulot [France] ; S E Bojesen [Danemark] ; B G Nordestgaard [Danemark] ; H. Flyer [Danemark] ; H. Brenner [Allemagne] ; A K Dieffenbach [Allemagne] ; V. Arndt [Allemagne] ; C. Stegmaier [Allemagne] ; A. Mannermaa [Finlande] ; V. Kataja [Finlande] ; V-M Kosma [Finlande] ; J M Hartikainen [Finlande] ; D. Lambrechts [Belgique] ; B T Yesilyurt [Belgique] ; G. Floris [Belgique] ; K. Leunen [Belgique] ; J. Chang-Claude [Allemagne] ; A. Rudolph [Allemagne] ; P. Seibold [Allemagne] ; D. Flesch-Janys [Allemagne] ; X. Wang [États-Unis] ; J E Olson [États-Unis] ; C. Vachon [États-Unis] ; K. Purrington [États-Unis] ; G G Giles [Australie] ; G. Severi [Australie] ; L. Baglietto [Australie] ; C A Haiman [États-Unis] ; B E Henderson [États-Unis] ; F. Schumacher [États-Unis] ; L. Le Marchand [États-Unis] ; J. Simard [Canada] ; M. Dumont [Canada] ; M S Goldberg [Canada] ; F. Labrèche [Canada] ; R. Winqvist [Finlande] ; K. Pylk S [Finlande] ; A. Jukkola-Vuorinen [Finlande] ; M. Grip [Finlande] ; P. Devilee [Pays-Bas] ; R A E M. Tollenaar [Pays-Bas] ; C. Seynaeve [Pays-Bas] ; M. García-Closas [Royaume-Uni, États-Unis] ; S J Chanock [États-Unis] ; J. Lissowska [Pologne] ; J D Figueroa [États-Unis] ; K. Czene [Suède] ; M. Eriksson [Suède] ; K. Humphreys [Suède] ; H. Darabi [Suède] ; M J Hooning [Pays-Bas] ; M. Kriege [Pays-Bas] ; J M Collée [Pays-Bas] ; M. Tilanus-Linthorst [Pays-Bas] ; J. Li [Singapour] ; A. Jakubowska [Pologne] ; J. Lubinski [Pologne] ; K. Jaworska-Bieniek [Pologne] ; K. Durda [Pologne] ; H. Nevanlinna [Finlande] ; T A Muranen [Finlande] ; K. Aittom Ki [Finlande] ; C. Blomqvist [Finlande] ; N. Bogdanova [Allemagne] ; T. Dörk [Allemagne] ; P. Hall [Suède] ; G. Chenevix-Trench [Australie] ; D F Easton [Royaume-Uni] ; P D P. Pharoah [Royaume-Uni] ; J I Arias-Perez [Espagne] ; P. Zamora [Espagne] ; J. Benítez [Espagne] ; R L Milne [Espagne, Australie]Source :
- British Journal of Cancer [ 0007-0920 ] ; 2014.
Abstract
Breast cancer is one of the most common malignancies in women. Genome-wide association studies have identified
Data were combined from 49 studies, including 53 835 cases and 50 156 controls, of which 89 050 (46 450 cases and 42 600 controls) were of European ancestry, 12 893 (6269 cases and 6624 controls) of Asian and 2048 (1116 cases and 932 controls) of African ancestry. Associations with risk of breast cancer, overall and by disease sub-type, were assessed using unconditional logistic regression.
Little evidence of association with breast cancer risk was observed for SNPs in the FGF receptor genes. The strongest evidence in European women was for rs743682 in
Our results suggest that common variants in the other FGF receptors are not associated with risk of breast cancer to the degree observed for
Url:
DOI: 10.1038/bjc.2013.769
PubMed: 24548884
PubMed Central: 3929867
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W. Blot<affiliation><nlm:aff id="aff56"><institution>Department of Medicine, Vanderbilt University</institution>
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<affiliation><nlm:aff id="aff56"><institution>Department of Medicine, Vanderbilt University</institution>
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<wicri:noCountry code="nlm country">TN USA</wicri:noCountry>
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Le document en format XML
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<author><name sortKey="Margolin, S" sort="Margolin, S" uniqKey="Margolin S" first="S" last="Margolin">S. Margolin</name>
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<country xml:lang="fr">Suède</country>
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<author><name sortKey="Swerdlow, A" sort="Swerdlow, A" uniqKey="Swerdlow A" first="A" last="Swerdlow">A. Swerdlow</name>
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<affiliation wicri:level="1"><nlm:aff id="aff13"><institution>Division of Breast Cancer Research, The Institute of Cancer Research</institution>
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<country xml:lang="fr">Royaume-Uni</country>
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<author><name sortKey="Ashworth, A" sort="Ashworth, A" uniqKey="Ashworth A" first="A" last="Ashworth">A. Ashworth</name>
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<country xml:lang="fr">Royaume-Uni</country>
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<author><name sortKey="Orr, N" sort="Orr, N" uniqKey="Orr N" first="N" last="Orr">N. Orr</name>
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<country xml:lang="fr">Royaume-Uni</country>
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<author><name sortKey="Jones, M" sort="Jones, M" uniqKey="Jones M" first="M" last="Jones">M. Jones</name>
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</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="Matsuo, K" sort="Matsuo, K" uniqKey="Matsuo K" first="K" last="Matsuo">K. Matsuo</name>
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</nlm:aff>
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<author><name sortKey="Ito, H" sort="Ito, H" uniqKey="Ito H" first="H" last="Ito">H. Ito</name>
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<author><name sortKey="Iwata, H" sort="Iwata, H" uniqKey="Iwata H" first="H" last="Iwata">H. Iwata</name>
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<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="Kondo, N" sort="Kondo, N" uniqKey="Kondo N" first="N" last="Kondo">N. Kondo</name>
<affiliation wicri:level="1"><nlm:aff id="aff17"><institution>Department of Breast Oncology, Aichi Cancer Center Hospital</institution>
, Nagoya,<country>Japan</country>
</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="Hartman, M" sort="Hartman, M" uniqKey="Hartman M" first="M" last="Hartman">M. Hartman</name>
<affiliation wicri:level="1"><nlm:aff id="aff20"><institution>Saw Swee Hock School of Public Health, Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System</institution>
, Singapore,<country>Singapore</country>
</nlm:aff>
<country xml:lang="fr">Singapour</country>
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<author><name sortKey="Hui, M" sort="Hui, M" uniqKey="Hui M" first="M" last="Hui">M. Hui</name>
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, Singapore,<country>Singapore</country>
</nlm:aff>
<country xml:lang="fr">Singapour</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
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<author><name sortKey="Lim, W Y" sort="Lim, W Y" uniqKey="Lim W" first="W Y" last="Lim">W Y Lim</name>
<affiliation wicri:level="1"><nlm:aff id="aff21"><institution>Saw Swee Hock School of Public Health, National University of Singapore and National University Health System</institution>
, Singapore,<country>Singapore</country>
</nlm:aff>
<country xml:lang="fr">Singapour</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
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<author><name sortKey="T C Iau, P" sort="T C Iau, P" uniqKey="T C Iau P" first="P" last="T-C Iau">P. T-C Iau</name>
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</nlm:aff>
<country xml:lang="fr">Singapour</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="Sawyer, E" sort="Sawyer, E" uniqKey="Sawyer E" first="E" last="Sawyer">E. Sawyer</name>
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</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
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<author><name sortKey="Tomlinson, I" sort="Tomlinson, I" uniqKey="Tomlinson I" first="I" last="Tomlinson">I. Tomlinson</name>
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</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<affiliation wicri:level="1"><nlm:aff id="aff25"><institution>Oxford Biomedical Research Centre, University of Oxford</institution>
, Oxford,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kerin, M" sort="Kerin, M" uniqKey="Kerin M" first="M" last="Kerin">M. Kerin</name>
<affiliation wicri:level="1"><nlm:aff id="aff26"><institution>School of Medicine, Clinical Science Institute, National University of Ireland</institution>
, Galway,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Miller, N" sort="Miller, N" uniqKey="Miller N" first="N" last="Miller">N. Miller</name>
<affiliation wicri:level="1"><nlm:aff id="aff26"><institution>School of Medicine, Clinical Science Institute, National University of Ireland</institution>
, Galway,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kang, D" sort="Kang, D" uniqKey="Kang D" first="D" last="Kang">D. Kang</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Department of Preventive Medicine, Seoul National University College of Medicine</institution>
, Seoul,<country>Korea</country>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff28"><institution>Department of Biomedical Sciences, Seoul National University Graduate School</institution>
, Seoul,<country>Korea</country>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Choi, J Y" sort="Choi, J Y" uniqKey="Choi J" first="J-Y" last="Choi">J-Y Choi</name>
<affiliation wicri:level="1"><nlm:aff id="aff28"><institution>Department of Biomedical Sciences, Seoul National University Graduate School</institution>
, Seoul,<country>Korea</country>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Park, S K" sort="Park, S K" uniqKey="Park S" first="S K" last="Park">S K Park</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Department of Preventive Medicine, Seoul National University College of Medicine</institution>
, Seoul,<country>Korea</country>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff28"><institution>Department of Biomedical Sciences, Seoul National University Graduate School</institution>
, Seoul,<country>Korea</country>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Noh, D Y" sort="Noh, D Y" uniqKey="Noh D" first="D-Y" last="Noh">D-Y Noh</name>
<affiliation wicri:level="1"><nlm:aff id="aff29"><institution>Department of Surgery, Seoul National University College of Medicine</institution>
, Seoul,<country>Korea</country>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hopper, J L" sort="Hopper, J L" uniqKey="Hopper J" first="J L" last="Hopper">J L Hopper</name>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne</institution>
, Melbourne, Victoria,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schmidt, D F" sort="Schmidt, D F" uniqKey="Schmidt D" first="D F" last="Schmidt">D F Schmidt</name>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne</institution>
, Melbourne, Victoria,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Makalic, E" sort="Makalic, E" uniqKey="Makalic E" first="E" last="Makalic">E. Makalic</name>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne</institution>
, Melbourne, Victoria,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Southey, M C" sort="Southey, M C" uniqKey="Southey M" first="M C" last="Southey">M C Southey</name>
<affiliation wicri:level="1"><nlm:aff id="aff31"><institution>Department of Pathology, University of Melbourne</institution>
, Melbourne, Victoria,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Teo, S H" sort="Teo, S H" uniqKey="Teo S" first="S H" last="Teo">S H Teo</name>
<affiliation wicri:level="1"><nlm:aff id="aff32"><institution>Cancer Research Initiatives Foundation, Sime Darby Medical Centre</institution>
, Subang Jaya,<country>Malaysia</country>
</nlm:aff>
<country xml:lang="fr">Malaisie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff33"><institution>Breast Cancer Research Unit, University Malaya Cancer Research Institute, University Malaya Medical Centre</institution>
, Kuala Lumpur,<country>Malaysia</country>
</nlm:aff>
<country xml:lang="fr">Malaisie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Yip, C H" sort="Yip, C H" uniqKey="Yip C" first="C H" last="Yip">C H Yip</name>
<affiliation wicri:level="1"><nlm:aff id="aff33"><institution>Breast Cancer Research Unit, University Malaya Cancer Research Institute, University Malaya Medical Centre</institution>
, Kuala Lumpur,<country>Malaysia</country>
</nlm:aff>
<country xml:lang="fr">Malaisie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sivanandan, K" sort="Sivanandan, K" uniqKey="Sivanandan K" first="K" last="Sivanandan">K. Sivanandan</name>
<affiliation wicri:level="1"><nlm:aff id="aff32"><institution>Cancer Research Initiatives Foundation, Sime Darby Medical Centre</institution>
, Subang Jaya,<country>Malaysia</country>
</nlm:aff>
<country xml:lang="fr">Malaisie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tay, W T" sort="Tay, W T" uniqKey="Tay W" first="W-T" last="Tay">W-T Tay</name>
<affiliation wicri:level="1"><nlm:aff id="aff34"><institution>Singapore Eye Research Institute, National University of Singapore</institution>
,<country>Singapore</country>
</nlm:aff>
<country xml:lang="fr">Singapour</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Brauch, H" sort="Brauch, H" uniqKey="Brauch H" first="H" last="Brauch">H. Brauch</name>
<affiliation wicri:level="1"><nlm:aff id="aff35"><institution>Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology</institution>
, Stuttgart,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff36"><institution>University of Tübingen</institution>
,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bruning, T" sort="Bruning, T" uniqKey="Bruning T" first="T" last="Brüning">T. Brüning</name>
<affiliation wicri:level="1"><nlm:aff id="aff37"><institution>Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-University Bochum (IPA)</institution>
,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hamann, U" sort="Hamann, U" uniqKey="Hamann U" first="U" last="Hamann">U. Hamann</name>
<affiliation wicri:level="1"><nlm:aff id="aff38"><institution>Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg</institution>
,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Dunning, A M" sort="Dunning, A M" uniqKey="Dunning A" first="A M" last="Dunning">A M Dunning</name>
<affiliation wicri:level="1"><nlm:aff id="aff42"><institution>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge</institution>
, Cambridge,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Shah, M" sort="Shah, M" uniqKey="Shah M" first="M" last="Shah">M. Shah</name>
<affiliation wicri:level="1"><nlm:aff id="aff42"><institution>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge</institution>
, Cambridge,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Andrulis, I L" sort="Andrulis, I L" uniqKey="Andrulis I" first="I L" last="Andrulis">I L Andrulis</name>
<affiliation wicri:level="1"><nlm:aff id="aff43"><institution>Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital</institution>
, Toronto, Ontario,<country>Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff44"><institution>Department of Molecular Genetics, University of Toronto</institution>
, Toronto, Ontario,<country>Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Knight, J A" sort="Knight, J A" uniqKey="Knight J" first="J A" last="Knight">J A Knight</name>
<affiliation wicri:level="1"><nlm:aff id="aff43"><institution>Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital</institution>
, Toronto, Ontario,<country>Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff45"><institution>Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto</institution>
, Toronto, Ontario,<country>Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Glendon, G" sort="Glendon, G" uniqKey="Glendon G" first="G" last="Glendon">G. Glendon</name>
<affiliation wicri:level="1"><nlm:aff id="aff46"><institution>Ontario Cancer Genetics Network, Lunenfeld-Tanenbaum Research Institute</institution>
, Toronto, Ontario,<country>Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tchatchou, S" sort="Tchatchou, S" uniqKey="Tchatchou S" first="S" last="Tchatchou">S. Tchatchou</name>
<affiliation wicri:level="1"><nlm:aff id="aff43"><institution>Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital</institution>
, Toronto, Ontario,<country>Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schmidt, M K" sort="Schmidt, M K" uniqKey="Schmidt M" first="M K" last="Schmidt">M K Schmidt</name>
<affiliation wicri:level="1"><nlm:aff id="aff47"><institution>Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital</institution>
, Amsterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Broeks, A" sort="Broeks, A" uniqKey="Broeks A" first="A" last="Broeks">A. Broeks</name>
<affiliation wicri:level="1"><nlm:aff id="aff47"><institution>Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital</institution>
, Amsterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rosenberg, E H" sort="Rosenberg, E H" uniqKey="Rosenberg E" first="E H" last="Rosenberg">E H Rosenberg</name>
<affiliation wicri:level="1"><nlm:aff id="aff47"><institution>Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital</institution>
, Amsterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van T Veer, L J" sort="Van T Veer, L J" uniqKey="Van T Veer L" first="L J" last="Van'T Veer">L J Van'T Veer</name>
<affiliation wicri:level="1"><nlm:aff id="aff47"><institution>Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital</institution>
, Amsterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Fasching, P A" sort="Fasching, P A" uniqKey="Fasching P" first="P A" last="Fasching">P A Fasching</name>
<affiliation wicri:level="1"><nlm:aff id="aff48"><institution>Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN</institution>
, Erlangen,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff49"><institution>David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology, University of California at Los Angeles</institution>
, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Renner, S P" sort="Renner, S P" uniqKey="Renner S" first="S P" last="Renner">S P Renner</name>
<affiliation wicri:level="1"><nlm:aff id="aff48"><institution>Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN</institution>
, Erlangen,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ekici, A B" sort="Ekici, A B" uniqKey="Ekici A" first="A B" last="Ekici">A B Ekici</name>
<affiliation wicri:level="1"><nlm:aff id="aff50"><institution>Institute of Human Genetics, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg</institution>
, Erlangen,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Beckmann, M W" sort="Beckmann, M W" uniqKey="Beckmann M" first="M W" last="Beckmann">M W Beckmann</name>
<affiliation wicri:level="1"><nlm:aff id="aff48"><institution>Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN</institution>
, Erlangen,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Shen, C Y" sort="Shen, C Y" uniqKey="Shen C" first="C-Y" last="Shen">C-Y Shen</name>
<affiliation wicri:level="1"><nlm:aff id="aff51"><institution>Institute of Biomedical Sciences, Academia Sinica</institution>
, Taipei,<country>Taiwan</country>
</nlm:aff>
<country xml:lang="fr">Taïwan</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff52"><institution>College of Public Health, China Medical University</institution>
, Taichong,<country>Taiwan</country>
</nlm:aff>
<country xml:lang="fr">Taïwan</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hsiung, C N" sort="Hsiung, C N" uniqKey="Hsiung C" first="C-N" last="Hsiung">C-N Hsiung</name>
<affiliation wicri:level="1"><nlm:aff id="aff51"><institution>Institute of Biomedical Sciences, Academia Sinica</institution>
, Taipei,<country>Taiwan</country>
</nlm:aff>
<country xml:lang="fr">Taïwan</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Yu, J C" sort="Yu, J C" uniqKey="Yu J" first="J-C" last="Yu">J-C Yu</name>
<affiliation wicri:level="1"><nlm:aff id="aff53"><institution>Tri-Service General Hospital</institution>
, Taipei,<country>Taiwan</country>
</nlm:aff>
<country xml:lang="fr">Taïwan</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hou, M F" sort="Hou, M F" uniqKey="Hou M" first="M-F" last="Hou">M-F Hou</name>
<affiliation wicri:level="1"><nlm:aff id="aff54"><institution>Cancer Center, Kaohsiung Medical University Chung-Ho Memorial Hospital</institution>
, Kaohsiung,<country>Taiwan</country>
</nlm:aff>
<country xml:lang="fr">Taïwan</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff55"><institution>Department of Surgery, Kaohsiung Medical University Chung-Ho Memorial Hospital</institution>
, Kaohsiung,<country>Taiwan</country>
</nlm:aff>
<country xml:lang="fr">Taïwan</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Blot, W" sort="Blot, W" uniqKey="Blot W" first="W" last="Blot">W. Blot</name>
<affiliation><nlm:aff id="aff56"><institution>Department of Medicine, Vanderbilt University</institution>
, Nashville,<country>TN USA</country>
</nlm:aff>
<wicri:noCountry code="nlm country">TN USA</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Cai, Q" sort="Cai, Q" uniqKey="Cai Q" first="Q" last="Cai">Q. Cai</name>
<affiliation><nlm:aff id="aff56"><institution>Department of Medicine, Vanderbilt University</institution>
, Nashville,<country>TN USA</country>
</nlm:aff>
<wicri:noCountry code="nlm country">TN USA</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Wu, A H" sort="Wu, A H" uniqKey="Wu A" first="A H" last="Wu">A H Wu</name>
<affiliation wicri:level="1"><nlm:aff id="aff57"><institution>Department of Preventive Medicine, Keck School of Medicine, University of Southern California</institution>
, Los Angeles, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tseng, C C" sort="Tseng, C C" uniqKey="Tseng C" first="C-C" last="Tseng">C-C Tseng</name>
<affiliation wicri:level="1"><nlm:aff id="aff57"><institution>Department of Preventive Medicine, Keck School of Medicine, University of Southern California</institution>
, Los Angeles, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Den Berg, D" sort="Van Den Berg, D" uniqKey="Van Den Berg D" first="D" last="Van Den Berg">D. Van Den Berg</name>
<affiliation wicri:level="1"><nlm:aff id="aff57"><institution>Department of Preventive Medicine, Keck School of Medicine, University of Southern California</institution>
, Los Angeles, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Stram, D O" sort="Stram, D O" uniqKey="Stram D" first="D O" last="Stram">D O Stram</name>
<affiliation wicri:level="1"><nlm:aff id="aff57"><institution>Department of Preventive Medicine, Keck School of Medicine, University of Southern California</institution>
, Los Angeles, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Cox, A" sort="Cox, A" uniqKey="Cox A" first="A" last="Cox">A. Cox</name>
<affiliation wicri:level="1"><nlm:aff id="aff58"><institution>CRUK/YCR Sheffield Cancer Research Centre, Department of Oncology, University of Sheffield</institution>
, Sheffield,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Brock, I W" sort="Brock, I W" uniqKey="Brock I" first="I W" last="Brock">I W Brock</name>
<affiliation wicri:level="1"><nlm:aff id="aff58"><institution>CRUK/YCR Sheffield Cancer Research Centre, Department of Oncology, University of Sheffield</institution>
, Sheffield,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Reed, M W R" sort="Reed, M W R" uniqKey="Reed M" first="M W R" last="Reed">M W R. Reed</name>
<affiliation wicri:level="1"><nlm:aff id="aff58"><institution>CRUK/YCR Sheffield Cancer Research Centre, Department of Oncology, University of Sheffield</institution>
, Sheffield,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Muir, K" sort="Muir, K" uniqKey="Muir K" first="K" last="Muir">K. Muir</name>
<affiliation wicri:level="1"><nlm:aff id="aff59"><institution>Institute of Population Health, University of Manchester</institution>
, Manchester,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff60"><institution>Division of Health Sciences, Warwick Medical School</institution>
, Coventry,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lophatananon, A" sort="Lophatananon, A" uniqKey="Lophatananon A" first="A" last="Lophatananon">A. Lophatananon</name>
<affiliation wicri:level="1"><nlm:aff id="aff60"><institution>Division of Health Sciences, Warwick Medical School</institution>
, Coventry,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Stewart Brown, S" sort="Stewart Brown, S" uniqKey="Stewart Brown S" first="S" last="Stewart-Brown">S. Stewart-Brown</name>
<affiliation wicri:level="1"><nlm:aff id="aff60"><institution>Division of Health Sciences, Warwick Medical School</institution>
, Coventry,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Siriwanarangsan, P" sort="Siriwanarangsan, P" uniqKey="Siriwanarangsan P" first="P" last="Siriwanarangsan">P. Siriwanarangsan</name>
<affiliation wicri:level="1"><nlm:aff id="aff61"><institution>Ministry of Public Health</institution>
, Bangkok,<country>Thailand</country>
</nlm:aff>
<country xml:lang="fr">Thaïlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Zheng, W" sort="Zheng, W" uniqKey="Zheng W" first="W" last="Zheng">W. Zheng</name>
<affiliation wicri:level="1"><nlm:aff id="aff62"><institution>Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center</institution>
, Nashville, TN,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Deming Halverson, S" sort="Deming Halverson, S" uniqKey="Deming Halverson S" first="S" last="Deming-Halverson">S. Deming-Halverson</name>
<affiliation wicri:level="1"><nlm:aff id="aff62"><institution>Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center</institution>
, Nashville, TN,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Shrubsole, M J" sort="Shrubsole, M J" uniqKey="Shrubsole M" first="M J" last="Shrubsole">M J Shrubsole</name>
<affiliation wicri:level="1"><nlm:aff id="aff62"><institution>Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center</institution>
, Nashville, TN,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Long, J" sort="Long, J" uniqKey="Long J" first="J" last="Long">J. Long</name>
<affiliation wicri:level="1"><nlm:aff id="aff62"><institution>Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center</institution>
, Nashville, TN,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Shu, X O" sort="Shu, X O" uniqKey="Shu X" first="X-O" last="Shu">X-O Shu</name>
<affiliation wicri:level="1"><nlm:aff id="aff62"><institution>Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center</institution>
, Nashville, TN,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lu, W" sort="Lu, W" uniqKey="Lu W" first="W" last="Lu">W. Lu</name>
<affiliation wicri:level="1"><nlm:aff id="aff63"><institution>Shanghai Center for Disease Control and Prevention</institution>
, Shanghai,<country>China</country>
</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gao, Y T" sort="Gao, Y T" uniqKey="Gao Y" first="Y-T" last="Gao">Y-T Gao</name>
<affiliation wicri:level="1"><nlm:aff id="aff64"><institution>Shanghai Cancer Institute</institution>
, Shanghai,<country>China</country>
</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Zhang, B" sort="Zhang, B" uniqKey="Zhang B" first="B" last="Zhang">B. Zhang</name>
<affiliation wicri:level="1"><nlm:aff id="aff62"><institution>Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center</institution>
, Nashville, TN,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Radice, P" sort="Radice, P" uniqKey="Radice P" first="P" last="Radice">P. Radice</name>
<affiliation wicri:level="1"><nlm:aff id="aff65"><institution>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori (INT)</institution>
, Milan,<country>Italy</country>
</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Peterlongo, P" sort="Peterlongo, P" uniqKey="Peterlongo P" first="P" last="Peterlongo">P. Peterlongo</name>
<affiliation wicri:level="1"><nlm:aff id="aff66"><institution>IFOM, Fondazione Istituto FIRC di Oncologia Molecolare</institution>
, Milan,<country>Italy</country>
</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Manoukian, S" sort="Manoukian, S" uniqKey="Manoukian S" first="S" last="Manoukian">S. Manoukian</name>
<affiliation wicri:level="1"><nlm:aff id="aff67"><institution>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori (INT)</institution>
, Milan,<country>Italy</country>
</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mariette, F" sort="Mariette, F" uniqKey="Mariette F" first="F" last="Mariette">F. Mariette</name>
<affiliation wicri:level="1"><nlm:aff id="aff66"><institution>IFOM, Fondazione Istituto FIRC di Oncologia Molecolare</institution>
, Milan,<country>Italy</country>
</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff68"><institution>Cogentech Cancer Genetic Test Laboratory</institution>
, Milan,<country>Italy</country>
</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sangrajrang, S" sort="Sangrajrang, S" uniqKey="Sangrajrang S" first="S" last="Sangrajrang">S. Sangrajrang</name>
<affiliation wicri:level="1"><nlm:aff id="aff69"><institution>National Cancer Institute</institution>
, Bangkok,<country>Thailand</country>
</nlm:aff>
<country xml:lang="fr">Thaïlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mckay, J" sort="Mckay, J" uniqKey="Mckay J" first="J" last="Mckay">J. Mckay</name>
<affiliation wicri:level="1"><nlm:aff id="aff70"><institution>Genetic Susceptibility Group, International Agency for Research on Cancer</institution>
, Lyon,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Couch, F J" sort="Couch, F J" uniqKey="Couch F" first="F J" last="Couch">F J Couch</name>
<affiliation wicri:level="1"><nlm:aff id="aff71"><institution>Department of Laboratory Medicine and Pathology, Mayo Clinic</institution>
, Rochester, MN,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Toland, A E" sort="Toland, A E" uniqKey="Toland A" first="A E" last="Toland">A E Toland</name>
<affiliation wicri:level="1"><nlm:aff id="aff72"><institution>Department of Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, The Ohio State University</institution>
, Columbus, OH,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Yannoukakos, D" sort="Yannoukakos, D" uniqKey="Yannoukakos D" first="D" last="Yannoukakos">D. Yannoukakos</name>
<affiliation wicri:level="1"><nlm:aff id="aff74"><institution>Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research "Demokritos"</institution>
, Athens,<country>Greece</country>
</nlm:aff>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Fletcher, O" sort="Fletcher, O" uniqKey="Fletcher O" first="O" last="Fletcher">O. Fletcher</name>
<affiliation wicri:level="1"><nlm:aff id="aff75"><institution>Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research</institution>
, London,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Johnson, N" sort="Johnson, N" uniqKey="Johnson N" first="N" last="Johnson">N. Johnson</name>
<affiliation wicri:level="1"><nlm:aff id="aff75"><institution>Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research</institution>
, London,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Silva, I Dos Santos" sort="Silva, I Dos Santos" uniqKey="Silva I" first="I Dos Santos" last="Silva">I Dos Santos Silva</name>
<affiliation wicri:level="1"><nlm:aff id="aff76"><institution>London School of Hygiene and Tropical Medicine</institution>
, London,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Peto, J" sort="Peto, J" uniqKey="Peto J" first="J" last="Peto">J. Peto</name>
<affiliation wicri:level="1"><nlm:aff id="aff76"><institution>London School of Hygiene and Tropical Medicine</institution>
, London,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Marme, F" sort="Marme, F" uniqKey="Marme F" first="F" last="Marme">F. Marme</name>
<affiliation wicri:level="1"><nlm:aff id="aff77"><institution>Department of Obstetrics and Gynecology, University of Heidelberg</institution>
, Heidelberg,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff78"><institution>National Center for Tumor Diseases, University of Heidelberg</institution>
, Heidelberg,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Burwinkel, B" sort="Burwinkel, B" uniqKey="Burwinkel B" first="B" last="Burwinkel">B. Burwinkel</name>
<affiliation wicri:level="1"><nlm:aff id="aff77"><institution>Department of Obstetrics and Gynecology, University of Heidelberg</institution>
, Heidelberg,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff79"><institution>Molecular Epidemiology Group, German Cancer Research Center (DKFZ)</institution>
, Heidelberg,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Guenel, P" sort="Guenel, P" uniqKey="Guenel P" first="P" last="Guénel">P. Guénel</name>
<affiliation wicri:level="1"><nlm:aff id="aff80"><institution>Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer</institution>
, Villejuif,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff81"><institution>University Paris-Sud, UMRS 1018</institution>
, Villejuif,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Truong, T" sort="Truong, T" uniqKey="Truong T" first="T" last="Truong">T. Truong</name>
<affiliation wicri:level="1"><nlm:aff id="aff80"><institution>Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer</institution>
, Villejuif,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff81"><institution>University Paris-Sud, UMRS 1018</institution>
, Villejuif,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sanchez, M" sort="Sanchez, M" uniqKey="Sanchez M" first="M" last="Sanchez">M. Sanchez</name>
<affiliation wicri:level="1"><nlm:aff id="aff80"><institution>Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer</institution>
, Villejuif,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff81"><institution>University Paris-Sud, UMRS 1018</institution>
, Villejuif,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mulot, C" sort="Mulot, C" uniqKey="Mulot C" first="C" last="Mulot">C. Mulot</name>
<affiliation wicri:level="1"><nlm:aff id="aff82"><institution>Inserm (National Institute of Health and Medical Research)</institution>
, U775 Paris,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff83"><institution>Centre de Ressources Biologiques EPIGENETEC</institution>
, Paris,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bojesen, S E" sort="Bojesen, S E" uniqKey="Bojesen S" first="S E" last="Bojesen">S E Bojesen</name>
<affiliation wicri:level="1"><nlm:aff id="aff84"><institution>Copenhagen General Population Study, Herlev University Hospital, University of Copenhagen</institution>
, Copenhagen,<country>Denmark</country>
</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff85"><institution>Department of Clinical Biochemistry, Herlev University Hospital, University of Copenhagen</institution>
, Copenhagen,<country>Denmark</country>
</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Nordestgaard, B G" sort="Nordestgaard, B G" uniqKey="Nordestgaard B" first="B G" last="Nordestgaard">B G Nordestgaard</name>
<affiliation wicri:level="1"><nlm:aff id="aff84"><institution>Copenhagen General Population Study, Herlev University Hospital, University of Copenhagen</institution>
, Copenhagen,<country>Denmark</country>
</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff85"><institution>Department of Clinical Biochemistry, Herlev University Hospital, University of Copenhagen</institution>
, Copenhagen,<country>Denmark</country>
</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Flyer, H" sort="Flyer, H" uniqKey="Flyer H" first="H" last="Flyer">H. Flyer</name>
<affiliation wicri:level="1"><nlm:aff id="aff86"><institution>Department of Breast Surgery, Herlev University Hospital, University of Copenhagen</institution>
, Copenhagen,<country>Denmark</country>
</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Brenner, H" sort="Brenner, H" uniqKey="Brenner H" first="H" last="Brenner">H. Brenner</name>
<affiliation wicri:level="1"><nlm:aff id="aff87"><institution>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ)</institution>
, Heidelberg,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff88"><institution>German Cancer Consortium (DKTK)</institution>
, Heidelberg,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Dieffenbach, A K" sort="Dieffenbach, A K" uniqKey="Dieffenbach A" first="A K" last="Dieffenbach">A K Dieffenbach</name>
<affiliation wicri:level="1"><nlm:aff id="aff87"><institution>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ)</institution>
, Heidelberg,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff88"><institution>German Cancer Consortium (DKTK)</institution>
, Heidelberg,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Arndt, V" sort="Arndt, V" uniqKey="Arndt V" first="V" last="Arndt">V. Arndt</name>
<affiliation wicri:level="1"><nlm:aff id="aff87"><institution>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ)</institution>
, Heidelberg,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Stegmaier, C" sort="Stegmaier, C" uniqKey="Stegmaier C" first="C" last="Stegmaier">C. Stegmaier</name>
<affiliation wicri:level="1"><nlm:aff id="aff89"><institution>Saarland Cancer Registry</institution>
, Saarbrücken,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mannermaa, A" sort="Mannermaa, A" uniqKey="Mannermaa A" first="A" last="Mannermaa">A. Mannermaa</name>
<affiliation wicri:level="1"><nlm:aff id="aff90"><institution>School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland</institution>
, Kuopio,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff91"><institution>Biocenter Kuopio, University of Eastern Finland</institution>
, Kuopio,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff92"><institution>Department of Clinical Pathology, Kuopio University Hospital</institution>
, Kuopio,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kataja, V" sort="Kataja, V" uniqKey="Kataja V" first="V" last="Kataja">V. Kataja</name>
<affiliation wicri:level="1"><nlm:aff id="aff91"><institution>Biocenter Kuopio, University of Eastern Finland</institution>
, Kuopio,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff93"><institution>School of Medicine, Institute of Clinical Medicine, Oncology, University of Eastern Finland</institution>
, Kuopio,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff94"><institution>Cancer Center, Kuopio University Hospital</institution>
, Kuopio,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kosma, V M" sort="Kosma, V M" uniqKey="Kosma V" first="V-M" last="Kosma">V-M Kosma</name>
<affiliation wicri:level="1"><nlm:aff id="aff90"><institution>School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland</institution>
, Kuopio,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff91"><institution>Biocenter Kuopio, University of Eastern Finland</institution>
, Kuopio,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff92"><institution>Department of Clinical Pathology, Kuopio University Hospital</institution>
, Kuopio,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hartikainen, J M" sort="Hartikainen, J M" uniqKey="Hartikainen J" first="J M" last="Hartikainen">J M Hartikainen</name>
<affiliation wicri:level="1"><nlm:aff id="aff90"><institution>School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland</institution>
, Kuopio,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff91"><institution>Biocenter Kuopio, University of Eastern Finland</institution>
, Kuopio,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff92"><institution>Department of Clinical Pathology, Kuopio University Hospital</institution>
, Kuopio,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lambrechts, D" sort="Lambrechts, D" uniqKey="Lambrechts D" first="D" last="Lambrechts">D. Lambrechts</name>
<affiliation wicri:level="1"><nlm:aff id="aff95"><institution>Vesalius Research Center (VRC), VIB</institution>
, Leuven,<country>Belgium</country>
</nlm:aff>
<country xml:lang="fr">Belgique</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Yesilyurt, B T" sort="Yesilyurt, B T" uniqKey="Yesilyurt B" first="B T" last="Yesilyurt">B T Yesilyurt</name>
<affiliation wicri:level="1"><nlm:aff id="aff95"><institution>Vesalius Research Center (VRC), VIB</institution>
, Leuven,<country>Belgium</country>
</nlm:aff>
<country xml:lang="fr">Belgique</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Floris, G" sort="Floris, G" uniqKey="Floris G" first="G" last="Floris">G. Floris</name>
<affiliation wicri:level="1"><nlm:aff id="aff96"><institution>Multidisciplinary Breast Center, University Hospital Gasthuisberg</institution>
, Leuven,<country>Belgium</country>
</nlm:aff>
<country xml:lang="fr">Belgique</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Leunen, K" sort="Leunen, K" uniqKey="Leunen K" first="K" last="Leunen">K. Leunen</name>
<affiliation wicri:level="1"><nlm:aff id="aff96"><institution>Multidisciplinary Breast Center, University Hospital Gasthuisberg</institution>
, Leuven,<country>Belgium</country>
</nlm:aff>
<country xml:lang="fr">Belgique</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Chang Claude, J" sort="Chang Claude, J" uniqKey="Chang Claude J" first="J" last="Chang-Claude">J. Chang-Claude</name>
<affiliation wicri:level="1"><nlm:aff id="aff97"><institution>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ)</institution>
, Heidelberg,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rudolph, A" sort="Rudolph, A" uniqKey="Rudolph A" first="A" last="Rudolph">A. Rudolph</name>
<affiliation wicri:level="1"><nlm:aff id="aff97"><institution>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ)</institution>
, Heidelberg,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Seibold, P" sort="Seibold, P" uniqKey="Seibold P" first="P" last="Seibold">P. Seibold</name>
<affiliation wicri:level="1"><nlm:aff id="aff97"><institution>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ)</institution>
, Heidelberg,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Flesch Janys, D" sort="Flesch Janys, D" uniqKey="Flesch Janys D" first="D" last="Flesch-Janys">D. Flesch-Janys</name>
<affiliation wicri:level="1"><nlm:aff id="aff98"><institution>Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf</institution>
, Hamburg,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff99"><institution>Department of Cancer Epidemiology/Clinical Cancer Registry, University Clinic Hamburg-Eppendorf</institution>
, Hamburg,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wang, X" sort="Wang, X" uniqKey="Wang X" first="X" last="Wang">X. Wang</name>
<affiliation wicri:level="1"><nlm:aff id="aff71"><institution>Department of Laboratory Medicine and Pathology, Mayo Clinic</institution>
, Rochester, MN,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Olson, J E" sort="Olson, J E" uniqKey="Olson J" first="J E" last="Olson">J E Olson</name>
<affiliation wicri:level="1"><nlm:aff id="aff100"><institution>Department of Health Sciences Research, Mayo Clinic</institution>
, Rochester, MN,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Vachon, C" sort="Vachon, C" uniqKey="Vachon C" first="C" last="Vachon">C. Vachon</name>
<affiliation wicri:level="1"><nlm:aff id="aff100"><institution>Department of Health Sciences Research, Mayo Clinic</institution>
, Rochester, MN,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Purrington, K" sort="Purrington, K" uniqKey="Purrington K" first="K" last="Purrington">K. Purrington</name>
<affiliation wicri:level="1"><nlm:aff id="aff100"><institution>Department of Health Sciences Research, Mayo Clinic</institution>
, Rochester, MN,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Giles, G G" sort="Giles, G G" uniqKey="Giles G" first="G G" last="Giles">G G Giles</name>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne</institution>
, Melbourne, Victoria,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff101"><institution>Cancer Epidemiology Centre, Cancer Council Victoria</institution>
, Melbourne,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Severi, G" sort="Severi, G" uniqKey="Severi G" first="G" last="Severi">G. Severi</name>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne</institution>
, Melbourne, Victoria,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff101"><institution>Cancer Epidemiology Centre, Cancer Council Victoria</institution>
, Melbourne,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Baglietto, L" sort="Baglietto, L" uniqKey="Baglietto L" first="L" last="Baglietto">L. Baglietto</name>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne</institution>
, Melbourne, Victoria,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff101"><institution>Cancer Epidemiology Centre, Cancer Council Victoria</institution>
, Melbourne,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Haiman, C A" sort="Haiman, C A" uniqKey="Haiman C" first="C A" last="Haiman">C A Haiman</name>
<affiliation wicri:level="1"><nlm:aff id="aff57"><institution>Department of Preventive Medicine, Keck School of Medicine, University of Southern California</institution>
, Los Angeles, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Henderson, B E" sort="Henderson, B E" uniqKey="Henderson B" first="B E" last="Henderson">B E Henderson</name>
<affiliation wicri:level="1"><nlm:aff id="aff57"><institution>Department of Preventive Medicine, Keck School of Medicine, University of Southern California</institution>
, Los Angeles, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schumacher, F" sort="Schumacher, F" uniqKey="Schumacher F" first="F" last="Schumacher">F. Schumacher</name>
<affiliation wicri:level="1"><nlm:aff id="aff57"><institution>Department of Preventive Medicine, Keck School of Medicine, University of Southern California</institution>
, Los Angeles, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Le Marchand, L" sort="Le Marchand, L" uniqKey="Le Marchand L" first="L" last="Le Marchand">L. Le Marchand</name>
<affiliation wicri:level="1"><nlm:aff id="aff102"><institution>University of Hawaii Cancer Center</institution>
, Honolulu, HI,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Simard, J" sort="Simard, J" uniqKey="Simard J" first="J" last="Simard">J. Simard</name>
<affiliation wicri:level="1"><nlm:aff id="aff103"><institution>Cancer Genomics Laboratory, Centre Hospitalier Universitaire de Quebec Research Center and Laval University</institution>
, Quebec,<country>Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Dumont, M" sort="Dumont, M" uniqKey="Dumont M" first="M" last="Dumont">M. Dumont</name>
<affiliation wicri:level="1"><nlm:aff id="aff103"><institution>Cancer Genomics Laboratory, Centre Hospitalier Universitaire de Quebec Research Center and Laval University</institution>
, Quebec,<country>Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Goldberg, M S" sort="Goldberg, M S" uniqKey="Goldberg M" first="M S" last="Goldberg">M S Goldberg</name>
<affiliation wicri:level="1"><nlm:aff id="aff104"><institution>Department of Medicine, McGill University, Montreal</institution>
, Montreal, Quebec,<country>Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff105"><institution>Division of Clinical Epidemiology, McGill University Health Centre, Royal Victoria Hospital</institution>
, Montreal, Quebec,<country>Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Labreche, F" sort="Labreche, F" uniqKey="Labreche F" first="F" last="Labrèche">F. Labrèche</name>
<affiliation wicri:level="1"><nlm:aff id="aff106"><institution>Département de médecine sociale et préventive, Département de santé environnementale et santé au travail, Université de Montréal</institution>
, Montreal, Quebec,<country>Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Winqvist, R" sort="Winqvist, R" uniqKey="Winqvist R" first="R" last="Winqvist">R. Winqvist</name>
<affiliation wicri:level="1"><nlm:aff id="aff107"><institution>Laboratory of Cancer Genetics and Tumor Biology, Department of Clinical Chemistry and Biocenter Oulu, University of Oulu, Oulu University Hospital</institution>
, Oulu,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pylk S, K" sort="Pylk S, K" uniqKey="Pylk S K" first="K" last="Pylk S">K. Pylk S</name>
<affiliation wicri:level="1"><nlm:aff id="aff107"><institution>Laboratory of Cancer Genetics and Tumor Biology, Department of Clinical Chemistry and Biocenter Oulu, University of Oulu, Oulu University Hospital</institution>
, Oulu,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Jukkola Vuorinen, A" sort="Jukkola Vuorinen, A" uniqKey="Jukkola Vuorinen A" first="A" last="Jukkola-Vuorinen">A. Jukkola-Vuorinen</name>
<affiliation wicri:level="1"><nlm:aff id="aff108"><institution>Department of Oncology, Oulu University Hospital, University of Oulu</institution>
, Oulu,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Grip, M" sort="Grip, M" uniqKey="Grip M" first="M" last="Grip">M. Grip</name>
<affiliation wicri:level="1"><nlm:aff id="aff109"><institution>Department of Surgery, Oulu University Hospital, University of Oulu</institution>
, Oulu,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Devilee, P" sort="Devilee, P" uniqKey="Devilee P" first="P" last="Devilee">P. Devilee</name>
<affiliation wicri:level="1"><nlm:aff id="aff110"><institution>Department of Human Genetics, Leiden University Medical Center</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tollenaar, R A E M" sort="Tollenaar, R A E M" uniqKey="Tollenaar R" first="R A E M" last="Tollenaar">R A E M. Tollenaar</name>
<affiliation wicri:level="1"><nlm:aff id="aff111"><institution>Department of Surgical Oncology, Leiden University Medical Center</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Seynaeve, C" sort="Seynaeve, C" uniqKey="Seynaeve C" first="C" last="Seynaeve">C. Seynaeve</name>
<affiliation wicri:level="1"><nlm:aff id="aff112"><institution>Department of Medical Oncology, Family Cancer Clinic, Erasmus University Medical Centre</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Garcia Closas, M" sort="Garcia Closas, M" uniqKey="Garcia Closas M" first="M" last="García-Closas">M. García-Closas</name>
<affiliation wicri:level="1"><nlm:aff id="aff13"><institution>Division of Breast Cancer Research, The Institute of Cancer Research</institution>
, London,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff113"><institution>Division of Cancer Epidemiology and Genetics, National Cancer Institute</institution>
, Rockville, MD,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff114"><institution>Division of Genetics and Epidemiology, Institute of Cancer Research and Breakthrough Breast Cancer Research Centre</institution>
, London,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Chanock, S J" sort="Chanock, S J" uniqKey="Chanock S" first="S J" last="Chanock">S J Chanock</name>
<affiliation wicri:level="1"><nlm:aff id="aff113"><institution>Division of Cancer Epidemiology and Genetics, National Cancer Institute</institution>
, Rockville, MD,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lissowska, J" sort="Lissowska, J" uniqKey="Lissowska J" first="J" last="Lissowska">J. Lissowska</name>
<affiliation wicri:level="1"><nlm:aff id="aff115"><institution>Department of Cancer Epidemiology and Prevention, M. Sklodowska-Curie Memorial Cancer Center & Institute of Oncology</institution>
, Warsaw,<country>Poland</country>
</nlm:aff>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Figueroa, J D" sort="Figueroa, J D" uniqKey="Figueroa J" first="J D" last="Figueroa">J D Figueroa</name>
<affiliation wicri:level="1"><nlm:aff id="aff113"><institution>Division of Cancer Epidemiology and Genetics, National Cancer Institute</institution>
, Rockville, MD,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Czene, K" sort="Czene, K" uniqKey="Czene K" first="K" last="Czene">K. Czene</name>
<affiliation wicri:level="1"><nlm:aff id="aff116"><institution>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet</institution>
, Stockholm,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Eriksson, M" sort="Eriksson, M" uniqKey="Eriksson M" first="M" last="Eriksson">M. Eriksson</name>
<affiliation wicri:level="1"><nlm:aff id="aff116"><institution>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet</institution>
, Stockholm,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Humphreys, K" sort="Humphreys, K" uniqKey="Humphreys K" first="K" last="Humphreys">K. Humphreys</name>
<affiliation wicri:level="1"><nlm:aff id="aff116"><institution>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet</institution>
, Stockholm,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Darabi, H" sort="Darabi, H" uniqKey="Darabi H" first="H" last="Darabi">H. Darabi</name>
<affiliation wicri:level="1"><nlm:aff id="aff116"><institution>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet</institution>
, Stockholm,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hooning, M J" sort="Hooning, M J" uniqKey="Hooning M" first="M J" last="Hooning">M J Hooning</name>
<affiliation wicri:level="1"><nlm:aff id="aff112"><institution>Department of Medical Oncology, Family Cancer Clinic, Erasmus University Medical Centre</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kriege, M" sort="Kriege, M" uniqKey="Kriege M" first="M" last="Kriege">M. Kriege</name>
<affiliation wicri:level="1"><nlm:aff id="aff112"><institution>Department of Medical Oncology, Family Cancer Clinic, Erasmus University Medical Centre</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Collee, J M" sort="Collee, J M" uniqKey="Collee J" first="J M" last="Collée">J M Collée</name>
<affiliation wicri:level="1"><nlm:aff id="aff117"><institution>Department of Clinical Genetics, Family Cancer Clinic, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tilanus Linthorst, M" sort="Tilanus Linthorst, M" uniqKey="Tilanus Linthorst M" first="M" last="Tilanus-Linthorst">M. Tilanus-Linthorst</name>
<affiliation wicri:level="1"><nlm:aff id="aff118"><institution>Department of Surgical Oncology, Family Cancer Clinic, Erasmus University Medical Centre</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Li, J" sort="Li, J" uniqKey="Li J" first="J" last="Li">J. Li</name>
<affiliation wicri:level="1"><nlm:aff id="aff119"><institution>Human Genetics Division, Genome Institute of Singapore</institution>
, Singapore,<country>Singapore</country>
</nlm:aff>
<country xml:lang="fr">Singapour</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Jakubowska, A" sort="Jakubowska, A" uniqKey="Jakubowska A" first="A" last="Jakubowska">A. Jakubowska</name>
<affiliation wicri:level="1"><nlm:aff id="aff120"><institution>Department of Genetics and Pathology, Pomeranian Medical University</institution>
, Szczecin,<country>Poland</country>
</nlm:aff>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lubinski, J" sort="Lubinski, J" uniqKey="Lubinski J" first="J" last="Lubinski">J. Lubinski</name>
<affiliation wicri:level="1"><nlm:aff id="aff120"><institution>Department of Genetics and Pathology, Pomeranian Medical University</institution>
, Szczecin,<country>Poland</country>
</nlm:aff>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Jaworska Bieniek, K" sort="Jaworska Bieniek, K" uniqKey="Jaworska Bieniek K" first="K" last="Jaworska-Bieniek">K. Jaworska-Bieniek</name>
<affiliation wicri:level="1"><nlm:aff id="aff120"><institution>Department of Genetics and Pathology, Pomeranian Medical University</institution>
, Szczecin,<country>Poland</country>
</nlm:aff>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Durda, K" sort="Durda, K" uniqKey="Durda K" first="K" last="Durda">K. Durda</name>
<affiliation wicri:level="1"><nlm:aff id="aff120"><institution>Department of Genetics and Pathology, Pomeranian Medical University</institution>
, Szczecin,<country>Poland</country>
</nlm:aff>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Nevanlinna, H" sort="Nevanlinna, H" uniqKey="Nevanlinna H" first="H" last="Nevanlinna">H. Nevanlinna</name>
<affiliation wicri:level="1"><nlm:aff id="aff121"><institution>Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Muranen, T A" sort="Muranen, T A" uniqKey="Muranen T" first="T A" last="Muranen">T A Muranen</name>
<affiliation wicri:level="1"><nlm:aff id="aff121"><institution>Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Aittom Ki, K" sort="Aittom Ki, K" uniqKey="Aittom Ki K" first="K" last="Aittom Ki">K. Aittom Ki</name>
<affiliation wicri:level="1"><nlm:aff id="aff122"><institution>Department of Clinical Genetics, Helsinki University Central Hospital</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Blomqvist, C" sort="Blomqvist, C" uniqKey="Blomqvist C" first="C" last="Blomqvist">C. Blomqvist</name>
<affiliation wicri:level="1"><nlm:aff id="aff123"><institution>Department of Oncology, Helsinki University Central Hospital</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bogdanova, N" sort="Bogdanova, N" uniqKey="Bogdanova N" first="N" last="Bogdanova">N. Bogdanova</name>
<affiliation wicri:level="1"><nlm:aff id="aff124"><institution>Department of Obstetrics and Gynaecology, Hannover Medical School</institution>
, Hannover,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff125"><institution>Department of Radiation Oncology, Hannover Medical School</institution>
, Hannover,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Dork, T" sort="Dork, T" uniqKey="Dork T" first="T" last="Dörk">T. Dörk</name>
<affiliation wicri:level="1"><nlm:aff id="aff124"><institution>Department of Obstetrics and Gynaecology, Hannover Medical School</institution>
, Hannover,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hall, P" sort="Hall, P" uniqKey="Hall P" first="P" last="Hall">P. Hall</name>
<affiliation wicri:level="1"><nlm:aff id="aff116"><institution>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet</institution>
, Stockholm,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Chenevix Trench, G" sort="Chenevix Trench, G" uniqKey="Chenevix Trench G" first="G" last="Chenevix-Trench">G. Chenevix-Trench</name>
<affiliation wicri:level="1"><nlm:aff id="aff19"><institution>QIMR Berghofer Institute of Medical Research</institution>
, Brisbane, Queensland,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Easton, D F" sort="Easton, D F" uniqKey="Easton D" first="D F" last="Easton">D F Easton</name>
<affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge</institution>
, Cambridge,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff42"><institution>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge</institution>
, Cambridge,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pharoah, P D P" sort="Pharoah, P D P" uniqKey="Pharoah P" first="P D P" last="Pharoah">P D P. Pharoah</name>
<affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge</institution>
, Cambridge,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff42"><institution>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge</institution>
, Cambridge,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Arias Perez, J I" sort="Arias Perez, J I" uniqKey="Arias Perez J" first="J I" last="Arias-Perez">J I Arias-Perez</name>
<affiliation wicri:level="1"><nlm:aff id="aff126"><institution>Servicio de Cirugía General y Especialidades, Hospital Monte Naranco</institution>
, Oviedo,<country>Spain</country>
</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Zamora, P" sort="Zamora, P" uniqKey="Zamora P" first="P" last="Zamora">P. Zamora</name>
<affiliation wicri:level="1"><nlm:aff id="aff127"><institution>Servicio de Oncología Médica, Hospital Universitario La Paz</institution>
, Madrid,<country>Spain</country>
</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Benitez, J" sort="Benitez, J" uniqKey="Benitez J" first="J" last="Benítez">J. Benítez</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO)</institution>
, Madrid,<country>Spain</country>
</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff5"><institution>Human Genotyping-CEGEN Unit, Spanish National Cancer Research Centre (CNIO)</institution>
, Madrid,<country>Spain</country>
</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Milne, R L" sort="Milne, R L" uniqKey="Milne R" first="R L" last="Milne">R L Milne</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO)</institution>
, Madrid,<country>Spain</country>
</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne</institution>
, Melbourne, Victoria,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff101"><institution>Cancer Epidemiology Centre, Cancer Council Victoria</institution>
, Melbourne,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">24548884</idno>
<idno type="pmc">3929867</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929867</idno>
<idno type="RBID">PMC:3929867</idno>
<idno type="doi">10.1038/bjc.2013.769</idno>
<date when="2014">2014</date>
<idno type="wicri:Area/Pmc/Corpus">000085</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000085</idno>
<idno type="wicri:Area/Pmc/Curation">000085</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000085</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium</title>
<author><name sortKey="Agarwal, D" sort="Agarwal, D" uniqKey="Agarwal D" first="D" last="Agarwal">D. Agarwal</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO)</institution>
, Madrid,<country>Spain</country>
</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Molecular, Cellular and Developmental Biology, Yale University</institution>
, New Haven, CT,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pineda, S" sort="Pineda, S" uniqKey="Pineda S" first="S" last="Pineda">S. Pineda</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO)</institution>
, Madrid,<country>Spain</country>
</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Michailidou, K" sort="Michailidou, K" uniqKey="Michailidou K" first="K" last="Michailidou">K. Michailidou</name>
<affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge</institution>
, Cambridge,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Herranz, J" sort="Herranz, J" uniqKey="Herranz J" first="J" last="Herranz">J. Herranz</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO)</institution>
, Madrid,<country>Spain</country>
</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff4"><institution>Biostatistics Unit, IMDEA Food Institute</institution>
, Madrid,<country>Spain</country>
</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pita, G" sort="Pita, G" uniqKey="Pita G" first="G" last="Pita">G. Pita</name>
<affiliation wicri:level="1"><nlm:aff id="aff5"><institution>Human Genotyping-CEGEN Unit, Spanish National Cancer Research Centre (CNIO)</institution>
, Madrid,<country>Spain</country>
</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Moreno, L T" sort="Moreno, L T" uniqKey="Moreno L" first="L T" last="Moreno">L T Moreno</name>
<affiliation wicri:level="1"><nlm:aff id="aff5"><institution>Human Genotyping-CEGEN Unit, Spanish National Cancer Research Centre (CNIO)</institution>
, Madrid,<country>Spain</country>
</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Alonso, M R" sort="Alonso, M R" uniqKey="Alonso M" first="M R" last="Alonso">M R Alonso</name>
<affiliation wicri:level="1"><nlm:aff id="aff5"><institution>Human Genotyping-CEGEN Unit, Spanish National Cancer Research Centre (CNIO)</institution>
, Madrid,<country>Spain</country>
</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Dennis, J" sort="Dennis, J" uniqKey="Dennis J" first="J" last="Dennis">J. Dennis</name>
<affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge</institution>
, Cambridge,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wang, Q" sort="Wang, Q" uniqKey="Wang Q" first="Q" last="Wang">Q. Wang</name>
<affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge</institution>
, Cambridge,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bolla, M K" sort="Bolla, M K" uniqKey="Bolla M" first="M K" last="Bolla">M K Bolla</name>
<affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge</institution>
, Cambridge,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Meyer, K B" sort="Meyer, K B" uniqKey="Meyer K" first="K B" last="Meyer">K B Meyer</name>
<affiliation wicri:level="1"><nlm:aff id="aff6"><institution>CRUK Cambridge Institute, University of Cambridge</institution>
, Cambridge,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Menendez Rodriguez, P" sort="Menendez Rodriguez, P" uniqKey="Menendez Rodriguez P" first="P" last="Menéndez-Rodríguez">P. Menéndez-Rodríguez</name>
<affiliation wicri:level="1"><nlm:aff id="aff7"><institution>Hospital Monte Naranco</institution>
, Oviedo,<country>Spain</country>
</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hardisson, D" sort="Hardisson, D" uniqKey="Hardisson D" first="D" last="Hardisson">D. Hardisson</name>
<affiliation wicri:level="1"><nlm:aff id="aff8"><institution>Department of Pathology, Hospital Universitario La Paz, IdiPAZ (Hospital La Paz Institute for Health Research) Universidad Autonoma de Madrid</institution>
, Madrid,<country>Spain</country>
</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mendiola, M" sort="Mendiola, M" uniqKey="Mendiola M" first="M" last="Mendiola">M. Mendiola</name>
<affiliation wicri:level="1"><nlm:aff id="aff9"><institution>Laboratory of Pathology and Oncology, Research Unit, Hospital Universitario La Paz, IdiPAZ</institution>
, Madrid,<country>Spain</country>
</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gonzalez Neira, A" sort="Gonzalez Neira, A" uniqKey="Gonzalez Neira A" first="A" last="González-Neira">A. González-Neira</name>
<affiliation wicri:level="1"><nlm:aff id="aff5"><institution>Human Genotyping-CEGEN Unit, Spanish National Cancer Research Centre (CNIO)</institution>
, Madrid,<country>Spain</country>
</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lindblom, A" sort="Lindblom, A" uniqKey="Lindblom A" first="A" last="Lindblom">A. Lindblom</name>
<affiliation wicri:level="1"><nlm:aff id="aff10"><institution>Department of Molecular Medicine and Surgery, Karolinska Institutet</institution>
, Stockholm,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Margolin, S" sort="Margolin, S" uniqKey="Margolin S" first="S" last="Margolin">S. Margolin</name>
<affiliation wicri:level="1"><nlm:aff id="aff11"><institution>Department of Oncology—Pathology, Karolinska Institutet</institution>
, Stockholm,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Swerdlow, A" sort="Swerdlow, A" uniqKey="Swerdlow A" first="A" last="Swerdlow">A. Swerdlow</name>
<affiliation wicri:level="1"><nlm:aff id="aff12"><institution>Division of Genetics and Epidemiology, The Institute of Cancer Research</institution>
, Sutton,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff13"><institution>Division of Breast Cancer Research, The Institute of Cancer Research</institution>
, London,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ashworth, A" sort="Ashworth, A" uniqKey="Ashworth A" first="A" last="Ashworth">A. Ashworth</name>
<affiliation wicri:level="1"><nlm:aff id="aff14"><institution>Breakthrough Breast Cancer Research Centre, Division of Breast Cancer Research, The Institute of Cancer Research</institution>
, London,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Orr, N" sort="Orr, N" uniqKey="Orr N" first="N" last="Orr">N. Orr</name>
<affiliation wicri:level="1"><nlm:aff id="aff14"><institution>Breakthrough Breast Cancer Research Centre, Division of Breast Cancer Research, The Institute of Cancer Research</institution>
, London,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Jones, M" sort="Jones, M" uniqKey="Jones M" first="M" last="Jones">M. Jones</name>
<affiliation wicri:level="1"><nlm:aff id="aff12"><institution>Division of Genetics and Epidemiology, The Institute of Cancer Research</institution>
, Sutton,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Matsuo, K" sort="Matsuo, K" uniqKey="Matsuo K" first="K" last="Matsuo">K. Matsuo</name>
<affiliation wicri:level="1"><nlm:aff id="aff15"><institution>Department of Preventive Medicine, Kyushu University Faculty of Medical Sciences</institution>
, Fukuoka,<country>Japan</country>
</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ito, H" sort="Ito, H" uniqKey="Ito H" first="H" last="Ito">H. Ito</name>
<affiliation wicri:level="1"><nlm:aff id="aff16"><institution>Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute</institution>
, Nagoya,<country>Japan</country>
</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Iwata, H" sort="Iwata, H" uniqKey="Iwata H" first="H" last="Iwata">H. Iwata</name>
<affiliation wicri:level="1"><nlm:aff id="aff17"><institution>Department of Breast Oncology, Aichi Cancer Center Hospital</institution>
, Nagoya,<country>Japan</country>
</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kondo, N" sort="Kondo, N" uniqKey="Kondo N" first="N" last="Kondo">N. Kondo</name>
<affiliation wicri:level="1"><nlm:aff id="aff17"><institution>Department of Breast Oncology, Aichi Cancer Center Hospital</institution>
, Nagoya,<country>Japan</country>
</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hartman, M" sort="Hartman, M" uniqKey="Hartman M" first="M" last="Hartman">M. Hartman</name>
<affiliation wicri:level="1"><nlm:aff id="aff20"><institution>Saw Swee Hock School of Public Health, Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System</institution>
, Singapore,<country>Singapore</country>
</nlm:aff>
<country xml:lang="fr">Singapour</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hui, M" sort="Hui, M" uniqKey="Hui M" first="M" last="Hui">M. Hui</name>
<affiliation wicri:level="1"><nlm:aff id="aff21"><institution>Saw Swee Hock School of Public Health, National University of Singapore and National University Health System</institution>
, Singapore,<country>Singapore</country>
</nlm:aff>
<country xml:lang="fr">Singapour</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lim, W Y" sort="Lim, W Y" uniqKey="Lim W" first="W Y" last="Lim">W Y Lim</name>
<affiliation wicri:level="1"><nlm:aff id="aff21"><institution>Saw Swee Hock School of Public Health, National University of Singapore and National University Health System</institution>
, Singapore,<country>Singapore</country>
</nlm:aff>
<country xml:lang="fr">Singapour</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="T C Iau, P" sort="T C Iau, P" uniqKey="T C Iau P" first="P" last="T-C Iau">P. T-C Iau</name>
<affiliation wicri:level="1"><nlm:aff id="aff22"><institution>Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System</institution>
, Singapore,<country>Singapore</country>
</nlm:aff>
<country xml:lang="fr">Singapour</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sawyer, E" sort="Sawyer, E" uniqKey="Sawyer E" first="E" last="Sawyer">E. Sawyer</name>
<affiliation wicri:level="1"><nlm:aff id="aff23"><institution>Research Oncology, Division of Cancer Studies, Kings College London Guy's Hospital</institution>
, London,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tomlinson, I" sort="Tomlinson, I" uniqKey="Tomlinson I" first="I" last="Tomlinson">I. Tomlinson</name>
<affiliation wicri:level="1"><nlm:aff id="aff24"><institution>Wellcome Trust Centre for Human Genetics, University of Oxford</institution>
, Oxford,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff25"><institution>Oxford Biomedical Research Centre, University of Oxford</institution>
, Oxford,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kerin, M" sort="Kerin, M" uniqKey="Kerin M" first="M" last="Kerin">M. Kerin</name>
<affiliation wicri:level="1"><nlm:aff id="aff26"><institution>School of Medicine, Clinical Science Institute, National University of Ireland</institution>
, Galway,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Miller, N" sort="Miller, N" uniqKey="Miller N" first="N" last="Miller">N. Miller</name>
<affiliation wicri:level="1"><nlm:aff id="aff26"><institution>School of Medicine, Clinical Science Institute, National University of Ireland</institution>
, Galway,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kang, D" sort="Kang, D" uniqKey="Kang D" first="D" last="Kang">D. Kang</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Department of Preventive Medicine, Seoul National University College of Medicine</institution>
, Seoul,<country>Korea</country>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff28"><institution>Department of Biomedical Sciences, Seoul National University Graduate School</institution>
, Seoul,<country>Korea</country>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Choi, J Y" sort="Choi, J Y" uniqKey="Choi J" first="J-Y" last="Choi">J-Y Choi</name>
<affiliation wicri:level="1"><nlm:aff id="aff28"><institution>Department of Biomedical Sciences, Seoul National University Graduate School</institution>
, Seoul,<country>Korea</country>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Park, S K" sort="Park, S K" uniqKey="Park S" first="S K" last="Park">S K Park</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Department of Preventive Medicine, Seoul National University College of Medicine</institution>
, Seoul,<country>Korea</country>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff28"><institution>Department of Biomedical Sciences, Seoul National University Graduate School</institution>
, Seoul,<country>Korea</country>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Noh, D Y" sort="Noh, D Y" uniqKey="Noh D" first="D-Y" last="Noh">D-Y Noh</name>
<affiliation wicri:level="1"><nlm:aff id="aff29"><institution>Department of Surgery, Seoul National University College of Medicine</institution>
, Seoul,<country>Korea</country>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hopper, J L" sort="Hopper, J L" uniqKey="Hopper J" first="J L" last="Hopper">J L Hopper</name>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne</institution>
, Melbourne, Victoria,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schmidt, D F" sort="Schmidt, D F" uniqKey="Schmidt D" first="D F" last="Schmidt">D F Schmidt</name>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne</institution>
, Melbourne, Victoria,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Makalic, E" sort="Makalic, E" uniqKey="Makalic E" first="E" last="Makalic">E. Makalic</name>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne</institution>
, Melbourne, Victoria,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Southey, M C" sort="Southey, M C" uniqKey="Southey M" first="M C" last="Southey">M C Southey</name>
<affiliation wicri:level="1"><nlm:aff id="aff31"><institution>Department of Pathology, University of Melbourne</institution>
, Melbourne, Victoria,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Teo, S H" sort="Teo, S H" uniqKey="Teo S" first="S H" last="Teo">S H Teo</name>
<affiliation wicri:level="1"><nlm:aff id="aff32"><institution>Cancer Research Initiatives Foundation, Sime Darby Medical Centre</institution>
, Subang Jaya,<country>Malaysia</country>
</nlm:aff>
<country xml:lang="fr">Malaisie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff33"><institution>Breast Cancer Research Unit, University Malaya Cancer Research Institute, University Malaya Medical Centre</institution>
, Kuala Lumpur,<country>Malaysia</country>
</nlm:aff>
<country xml:lang="fr">Malaisie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Yip, C H" sort="Yip, C H" uniqKey="Yip C" first="C H" last="Yip">C H Yip</name>
<affiliation wicri:level="1"><nlm:aff id="aff33"><institution>Breast Cancer Research Unit, University Malaya Cancer Research Institute, University Malaya Medical Centre</institution>
, Kuala Lumpur,<country>Malaysia</country>
</nlm:aff>
<country xml:lang="fr">Malaisie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sivanandan, K" sort="Sivanandan, K" uniqKey="Sivanandan K" first="K" last="Sivanandan">K. Sivanandan</name>
<affiliation wicri:level="1"><nlm:aff id="aff32"><institution>Cancer Research Initiatives Foundation, Sime Darby Medical Centre</institution>
, Subang Jaya,<country>Malaysia</country>
</nlm:aff>
<country xml:lang="fr">Malaisie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tay, W T" sort="Tay, W T" uniqKey="Tay W" first="W-T" last="Tay">W-T Tay</name>
<affiliation wicri:level="1"><nlm:aff id="aff34"><institution>Singapore Eye Research Institute, National University of Singapore</institution>
,<country>Singapore</country>
</nlm:aff>
<country xml:lang="fr">Singapour</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Brauch, H" sort="Brauch, H" uniqKey="Brauch H" first="H" last="Brauch">H. Brauch</name>
<affiliation wicri:level="1"><nlm:aff id="aff35"><institution>Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology</institution>
, Stuttgart,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff36"><institution>University of Tübingen</institution>
,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bruning, T" sort="Bruning, T" uniqKey="Bruning T" first="T" last="Brüning">T. Brüning</name>
<affiliation wicri:level="1"><nlm:aff id="aff37"><institution>Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-University Bochum (IPA)</institution>
,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hamann, U" sort="Hamann, U" uniqKey="Hamann U" first="U" last="Hamann">U. Hamann</name>
<affiliation wicri:level="1"><nlm:aff id="aff38"><institution>Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg</institution>
,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Dunning, A M" sort="Dunning, A M" uniqKey="Dunning A" first="A M" last="Dunning">A M Dunning</name>
<affiliation wicri:level="1"><nlm:aff id="aff42"><institution>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge</institution>
, Cambridge,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Shah, M" sort="Shah, M" uniqKey="Shah M" first="M" last="Shah">M. Shah</name>
<affiliation wicri:level="1"><nlm:aff id="aff42"><institution>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge</institution>
, Cambridge,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Andrulis, I L" sort="Andrulis, I L" uniqKey="Andrulis I" first="I L" last="Andrulis">I L Andrulis</name>
<affiliation wicri:level="1"><nlm:aff id="aff43"><institution>Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital</institution>
, Toronto, Ontario,<country>Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff44"><institution>Department of Molecular Genetics, University of Toronto</institution>
, Toronto, Ontario,<country>Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Knight, J A" sort="Knight, J A" uniqKey="Knight J" first="J A" last="Knight">J A Knight</name>
<affiliation wicri:level="1"><nlm:aff id="aff43"><institution>Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital</institution>
, Toronto, Ontario,<country>Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff45"><institution>Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto</institution>
, Toronto, Ontario,<country>Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Glendon, G" sort="Glendon, G" uniqKey="Glendon G" first="G" last="Glendon">G. Glendon</name>
<affiliation wicri:level="1"><nlm:aff id="aff46"><institution>Ontario Cancer Genetics Network, Lunenfeld-Tanenbaum Research Institute</institution>
, Toronto, Ontario,<country>Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tchatchou, S" sort="Tchatchou, S" uniqKey="Tchatchou S" first="S" last="Tchatchou">S. Tchatchou</name>
<affiliation wicri:level="1"><nlm:aff id="aff43"><institution>Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital</institution>
, Toronto, Ontario,<country>Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schmidt, M K" sort="Schmidt, M K" uniqKey="Schmidt M" first="M K" last="Schmidt">M K Schmidt</name>
<affiliation wicri:level="1"><nlm:aff id="aff47"><institution>Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital</institution>
, Amsterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Broeks, A" sort="Broeks, A" uniqKey="Broeks A" first="A" last="Broeks">A. Broeks</name>
<affiliation wicri:level="1"><nlm:aff id="aff47"><institution>Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital</institution>
, Amsterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rosenberg, E H" sort="Rosenberg, E H" uniqKey="Rosenberg E" first="E H" last="Rosenberg">E H Rosenberg</name>
<affiliation wicri:level="1"><nlm:aff id="aff47"><institution>Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital</institution>
, Amsterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van T Veer, L J" sort="Van T Veer, L J" uniqKey="Van T Veer L" first="L J" last="Van'T Veer">L J Van'T Veer</name>
<affiliation wicri:level="1"><nlm:aff id="aff47"><institution>Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital</institution>
, Amsterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Fasching, P A" sort="Fasching, P A" uniqKey="Fasching P" first="P A" last="Fasching">P A Fasching</name>
<affiliation wicri:level="1"><nlm:aff id="aff48"><institution>Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN</institution>
, Erlangen,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff49"><institution>David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology, University of California at Los Angeles</institution>
, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Renner, S P" sort="Renner, S P" uniqKey="Renner S" first="S P" last="Renner">S P Renner</name>
<affiliation wicri:level="1"><nlm:aff id="aff48"><institution>Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN</institution>
, Erlangen,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ekici, A B" sort="Ekici, A B" uniqKey="Ekici A" first="A B" last="Ekici">A B Ekici</name>
<affiliation wicri:level="1"><nlm:aff id="aff50"><institution>Institute of Human Genetics, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg</institution>
, Erlangen,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Beckmann, M W" sort="Beckmann, M W" uniqKey="Beckmann M" first="M W" last="Beckmann">M W Beckmann</name>
<affiliation wicri:level="1"><nlm:aff id="aff48"><institution>Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN</institution>
, Erlangen,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Shen, C Y" sort="Shen, C Y" uniqKey="Shen C" first="C-Y" last="Shen">C-Y Shen</name>
<affiliation wicri:level="1"><nlm:aff id="aff51"><institution>Institute of Biomedical Sciences, Academia Sinica</institution>
, Taipei,<country>Taiwan</country>
</nlm:aff>
<country xml:lang="fr">Taïwan</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff52"><institution>College of Public Health, China Medical University</institution>
, Taichong,<country>Taiwan</country>
</nlm:aff>
<country xml:lang="fr">Taïwan</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hsiung, C N" sort="Hsiung, C N" uniqKey="Hsiung C" first="C-N" last="Hsiung">C-N Hsiung</name>
<affiliation wicri:level="1"><nlm:aff id="aff51"><institution>Institute of Biomedical Sciences, Academia Sinica</institution>
, Taipei,<country>Taiwan</country>
</nlm:aff>
<country xml:lang="fr">Taïwan</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Yu, J C" sort="Yu, J C" uniqKey="Yu J" first="J-C" last="Yu">J-C Yu</name>
<affiliation wicri:level="1"><nlm:aff id="aff53"><institution>Tri-Service General Hospital</institution>
, Taipei,<country>Taiwan</country>
</nlm:aff>
<country xml:lang="fr">Taïwan</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hou, M F" sort="Hou, M F" uniqKey="Hou M" first="M-F" last="Hou">M-F Hou</name>
<affiliation wicri:level="1"><nlm:aff id="aff54"><institution>Cancer Center, Kaohsiung Medical University Chung-Ho Memorial Hospital</institution>
, Kaohsiung,<country>Taiwan</country>
</nlm:aff>
<country xml:lang="fr">Taïwan</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff55"><institution>Department of Surgery, Kaohsiung Medical University Chung-Ho Memorial Hospital</institution>
, Kaohsiung,<country>Taiwan</country>
</nlm:aff>
<country xml:lang="fr">Taïwan</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Blot, W" sort="Blot, W" uniqKey="Blot W" first="W" last="Blot">W. Blot</name>
<affiliation><nlm:aff id="aff56"><institution>Department of Medicine, Vanderbilt University</institution>
, Nashville,<country>TN USA</country>
</nlm:aff>
<wicri:noCountry code="nlm country">TN USA</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Cai, Q" sort="Cai, Q" uniqKey="Cai Q" first="Q" last="Cai">Q. Cai</name>
<affiliation><nlm:aff id="aff56"><institution>Department of Medicine, Vanderbilt University</institution>
, Nashville,<country>TN USA</country>
</nlm:aff>
<wicri:noCountry code="nlm country">TN USA</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Wu, A H" sort="Wu, A H" uniqKey="Wu A" first="A H" last="Wu">A H Wu</name>
<affiliation wicri:level="1"><nlm:aff id="aff57"><institution>Department of Preventive Medicine, Keck School of Medicine, University of Southern California</institution>
, Los Angeles, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tseng, C C" sort="Tseng, C C" uniqKey="Tseng C" first="C-C" last="Tseng">C-C Tseng</name>
<affiliation wicri:level="1"><nlm:aff id="aff57"><institution>Department of Preventive Medicine, Keck School of Medicine, University of Southern California</institution>
, Los Angeles, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Den Berg, D" sort="Van Den Berg, D" uniqKey="Van Den Berg D" first="D" last="Van Den Berg">D. Van Den Berg</name>
<affiliation wicri:level="1"><nlm:aff id="aff57"><institution>Department of Preventive Medicine, Keck School of Medicine, University of Southern California</institution>
, Los Angeles, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Stram, D O" sort="Stram, D O" uniqKey="Stram D" first="D O" last="Stram">D O Stram</name>
<affiliation wicri:level="1"><nlm:aff id="aff57"><institution>Department of Preventive Medicine, Keck School of Medicine, University of Southern California</institution>
, Los Angeles, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Cox, A" sort="Cox, A" uniqKey="Cox A" first="A" last="Cox">A. Cox</name>
<affiliation wicri:level="1"><nlm:aff id="aff58"><institution>CRUK/YCR Sheffield Cancer Research Centre, Department of Oncology, University of Sheffield</institution>
, Sheffield,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Brock, I W" sort="Brock, I W" uniqKey="Brock I" first="I W" last="Brock">I W Brock</name>
<affiliation wicri:level="1"><nlm:aff id="aff58"><institution>CRUK/YCR Sheffield Cancer Research Centre, Department of Oncology, University of Sheffield</institution>
, Sheffield,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Reed, M W R" sort="Reed, M W R" uniqKey="Reed M" first="M W R" last="Reed">M W R. Reed</name>
<affiliation wicri:level="1"><nlm:aff id="aff58"><institution>CRUK/YCR Sheffield Cancer Research Centre, Department of Oncology, University of Sheffield</institution>
, Sheffield,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Muir, K" sort="Muir, K" uniqKey="Muir K" first="K" last="Muir">K. Muir</name>
<affiliation wicri:level="1"><nlm:aff id="aff59"><institution>Institute of Population Health, University of Manchester</institution>
, Manchester,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff60"><institution>Division of Health Sciences, Warwick Medical School</institution>
, Coventry,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lophatananon, A" sort="Lophatananon, A" uniqKey="Lophatananon A" first="A" last="Lophatananon">A. Lophatananon</name>
<affiliation wicri:level="1"><nlm:aff id="aff60"><institution>Division of Health Sciences, Warwick Medical School</institution>
, Coventry,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Stewart Brown, S" sort="Stewart Brown, S" uniqKey="Stewart Brown S" first="S" last="Stewart-Brown">S. Stewart-Brown</name>
<affiliation wicri:level="1"><nlm:aff id="aff60"><institution>Division of Health Sciences, Warwick Medical School</institution>
, Coventry,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Siriwanarangsan, P" sort="Siriwanarangsan, P" uniqKey="Siriwanarangsan P" first="P" last="Siriwanarangsan">P. Siriwanarangsan</name>
<affiliation wicri:level="1"><nlm:aff id="aff61"><institution>Ministry of Public Health</institution>
, Bangkok,<country>Thailand</country>
</nlm:aff>
<country xml:lang="fr">Thaïlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Zheng, W" sort="Zheng, W" uniqKey="Zheng W" first="W" last="Zheng">W. Zheng</name>
<affiliation wicri:level="1"><nlm:aff id="aff62"><institution>Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center</institution>
, Nashville, TN,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Deming Halverson, S" sort="Deming Halverson, S" uniqKey="Deming Halverson S" first="S" last="Deming-Halverson">S. Deming-Halverson</name>
<affiliation wicri:level="1"><nlm:aff id="aff62"><institution>Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center</institution>
, Nashville, TN,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Shrubsole, M J" sort="Shrubsole, M J" uniqKey="Shrubsole M" first="M J" last="Shrubsole">M J Shrubsole</name>
<affiliation wicri:level="1"><nlm:aff id="aff62"><institution>Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center</institution>
, Nashville, TN,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Long, J" sort="Long, J" uniqKey="Long J" first="J" last="Long">J. Long</name>
<affiliation wicri:level="1"><nlm:aff id="aff62"><institution>Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center</institution>
, Nashville, TN,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Shu, X O" sort="Shu, X O" uniqKey="Shu X" first="X-O" last="Shu">X-O Shu</name>
<affiliation wicri:level="1"><nlm:aff id="aff62"><institution>Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center</institution>
, Nashville, TN,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lu, W" sort="Lu, W" uniqKey="Lu W" first="W" last="Lu">W. Lu</name>
<affiliation wicri:level="1"><nlm:aff id="aff63"><institution>Shanghai Center for Disease Control and Prevention</institution>
, Shanghai,<country>China</country>
</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gao, Y T" sort="Gao, Y T" uniqKey="Gao Y" first="Y-T" last="Gao">Y-T Gao</name>
<affiliation wicri:level="1"><nlm:aff id="aff64"><institution>Shanghai Cancer Institute</institution>
, Shanghai,<country>China</country>
</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Zhang, B" sort="Zhang, B" uniqKey="Zhang B" first="B" last="Zhang">B. Zhang</name>
<affiliation wicri:level="1"><nlm:aff id="aff62"><institution>Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center</institution>
, Nashville, TN,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Radice, P" sort="Radice, P" uniqKey="Radice P" first="P" last="Radice">P. Radice</name>
<affiliation wicri:level="1"><nlm:aff id="aff65"><institution>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori (INT)</institution>
, Milan,<country>Italy</country>
</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Peterlongo, P" sort="Peterlongo, P" uniqKey="Peterlongo P" first="P" last="Peterlongo">P. Peterlongo</name>
<affiliation wicri:level="1"><nlm:aff id="aff66"><institution>IFOM, Fondazione Istituto FIRC di Oncologia Molecolare</institution>
, Milan,<country>Italy</country>
</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Manoukian, S" sort="Manoukian, S" uniqKey="Manoukian S" first="S" last="Manoukian">S. Manoukian</name>
<affiliation wicri:level="1"><nlm:aff id="aff67"><institution>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori (INT)</institution>
, Milan,<country>Italy</country>
</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mariette, F" sort="Mariette, F" uniqKey="Mariette F" first="F" last="Mariette">F. Mariette</name>
<affiliation wicri:level="1"><nlm:aff id="aff66"><institution>IFOM, Fondazione Istituto FIRC di Oncologia Molecolare</institution>
, Milan,<country>Italy</country>
</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff68"><institution>Cogentech Cancer Genetic Test Laboratory</institution>
, Milan,<country>Italy</country>
</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sangrajrang, S" sort="Sangrajrang, S" uniqKey="Sangrajrang S" first="S" last="Sangrajrang">S. Sangrajrang</name>
<affiliation wicri:level="1"><nlm:aff id="aff69"><institution>National Cancer Institute</institution>
, Bangkok,<country>Thailand</country>
</nlm:aff>
<country xml:lang="fr">Thaïlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mckay, J" sort="Mckay, J" uniqKey="Mckay J" first="J" last="Mckay">J. Mckay</name>
<affiliation wicri:level="1"><nlm:aff id="aff70"><institution>Genetic Susceptibility Group, International Agency for Research on Cancer</institution>
, Lyon,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Couch, F J" sort="Couch, F J" uniqKey="Couch F" first="F J" last="Couch">F J Couch</name>
<affiliation wicri:level="1"><nlm:aff id="aff71"><institution>Department of Laboratory Medicine and Pathology, Mayo Clinic</institution>
, Rochester, MN,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Toland, A E" sort="Toland, A E" uniqKey="Toland A" first="A E" last="Toland">A E Toland</name>
<affiliation wicri:level="1"><nlm:aff id="aff72"><institution>Department of Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, The Ohio State University</institution>
, Columbus, OH,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Yannoukakos, D" sort="Yannoukakos, D" uniqKey="Yannoukakos D" first="D" last="Yannoukakos">D. Yannoukakos</name>
<affiliation wicri:level="1"><nlm:aff id="aff74"><institution>Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research "Demokritos"</institution>
, Athens,<country>Greece</country>
</nlm:aff>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Fletcher, O" sort="Fletcher, O" uniqKey="Fletcher O" first="O" last="Fletcher">O. Fletcher</name>
<affiliation wicri:level="1"><nlm:aff id="aff75"><institution>Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research</institution>
, London,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Johnson, N" sort="Johnson, N" uniqKey="Johnson N" first="N" last="Johnson">N. Johnson</name>
<affiliation wicri:level="1"><nlm:aff id="aff75"><institution>Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research</institution>
, London,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Silva, I Dos Santos" sort="Silva, I Dos Santos" uniqKey="Silva I" first="I Dos Santos" last="Silva">I Dos Santos Silva</name>
<affiliation wicri:level="1"><nlm:aff id="aff76"><institution>London School of Hygiene and Tropical Medicine</institution>
, London,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Peto, J" sort="Peto, J" uniqKey="Peto J" first="J" last="Peto">J. Peto</name>
<affiliation wicri:level="1"><nlm:aff id="aff76"><institution>London School of Hygiene and Tropical Medicine</institution>
, London,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Marme, F" sort="Marme, F" uniqKey="Marme F" first="F" last="Marme">F. Marme</name>
<affiliation wicri:level="1"><nlm:aff id="aff77"><institution>Department of Obstetrics and Gynecology, University of Heidelberg</institution>
, Heidelberg,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff78"><institution>National Center for Tumor Diseases, University of Heidelberg</institution>
, Heidelberg,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Burwinkel, B" sort="Burwinkel, B" uniqKey="Burwinkel B" first="B" last="Burwinkel">B. Burwinkel</name>
<affiliation wicri:level="1"><nlm:aff id="aff77"><institution>Department of Obstetrics and Gynecology, University of Heidelberg</institution>
, Heidelberg,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff79"><institution>Molecular Epidemiology Group, German Cancer Research Center (DKFZ)</institution>
, Heidelberg,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Guenel, P" sort="Guenel, P" uniqKey="Guenel P" first="P" last="Guénel">P. Guénel</name>
<affiliation wicri:level="1"><nlm:aff id="aff80"><institution>Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer</institution>
, Villejuif,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff81"><institution>University Paris-Sud, UMRS 1018</institution>
, Villejuif,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Truong, T" sort="Truong, T" uniqKey="Truong T" first="T" last="Truong">T. Truong</name>
<affiliation wicri:level="1"><nlm:aff id="aff80"><institution>Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer</institution>
, Villejuif,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff81"><institution>University Paris-Sud, UMRS 1018</institution>
, Villejuif,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sanchez, M" sort="Sanchez, M" uniqKey="Sanchez M" first="M" last="Sanchez">M. Sanchez</name>
<affiliation wicri:level="1"><nlm:aff id="aff80"><institution>Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer</institution>
, Villejuif,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff81"><institution>University Paris-Sud, UMRS 1018</institution>
, Villejuif,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mulot, C" sort="Mulot, C" uniqKey="Mulot C" first="C" last="Mulot">C. Mulot</name>
<affiliation wicri:level="1"><nlm:aff id="aff82"><institution>Inserm (National Institute of Health and Medical Research)</institution>
, U775 Paris,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff83"><institution>Centre de Ressources Biologiques EPIGENETEC</institution>
, Paris,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bojesen, S E" sort="Bojesen, S E" uniqKey="Bojesen S" first="S E" last="Bojesen">S E Bojesen</name>
<affiliation wicri:level="1"><nlm:aff id="aff84"><institution>Copenhagen General Population Study, Herlev University Hospital, University of Copenhagen</institution>
, Copenhagen,<country>Denmark</country>
</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff85"><institution>Department of Clinical Biochemistry, Herlev University Hospital, University of Copenhagen</institution>
, Copenhagen,<country>Denmark</country>
</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Nordestgaard, B G" sort="Nordestgaard, B G" uniqKey="Nordestgaard B" first="B G" last="Nordestgaard">B G Nordestgaard</name>
<affiliation wicri:level="1"><nlm:aff id="aff84"><institution>Copenhagen General Population Study, Herlev University Hospital, University of Copenhagen</institution>
, Copenhagen,<country>Denmark</country>
</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff85"><institution>Department of Clinical Biochemistry, Herlev University Hospital, University of Copenhagen</institution>
, Copenhagen,<country>Denmark</country>
</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Flyer, H" sort="Flyer, H" uniqKey="Flyer H" first="H" last="Flyer">H. Flyer</name>
<affiliation wicri:level="1"><nlm:aff id="aff86"><institution>Department of Breast Surgery, Herlev University Hospital, University of Copenhagen</institution>
, Copenhagen,<country>Denmark</country>
</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Brenner, H" sort="Brenner, H" uniqKey="Brenner H" first="H" last="Brenner">H. Brenner</name>
<affiliation wicri:level="1"><nlm:aff id="aff87"><institution>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ)</institution>
, Heidelberg,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff88"><institution>German Cancer Consortium (DKTK)</institution>
, Heidelberg,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Dieffenbach, A K" sort="Dieffenbach, A K" uniqKey="Dieffenbach A" first="A K" last="Dieffenbach">A K Dieffenbach</name>
<affiliation wicri:level="1"><nlm:aff id="aff87"><institution>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ)</institution>
, Heidelberg,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff88"><institution>German Cancer Consortium (DKTK)</institution>
, Heidelberg,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Arndt, V" sort="Arndt, V" uniqKey="Arndt V" first="V" last="Arndt">V. Arndt</name>
<affiliation wicri:level="1"><nlm:aff id="aff87"><institution>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ)</institution>
, Heidelberg,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Stegmaier, C" sort="Stegmaier, C" uniqKey="Stegmaier C" first="C" last="Stegmaier">C. Stegmaier</name>
<affiliation wicri:level="1"><nlm:aff id="aff89"><institution>Saarland Cancer Registry</institution>
, Saarbrücken,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mannermaa, A" sort="Mannermaa, A" uniqKey="Mannermaa A" first="A" last="Mannermaa">A. Mannermaa</name>
<affiliation wicri:level="1"><nlm:aff id="aff90"><institution>School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland</institution>
, Kuopio,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff91"><institution>Biocenter Kuopio, University of Eastern Finland</institution>
, Kuopio,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff92"><institution>Department of Clinical Pathology, Kuopio University Hospital</institution>
, Kuopio,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kataja, V" sort="Kataja, V" uniqKey="Kataja V" first="V" last="Kataja">V. Kataja</name>
<affiliation wicri:level="1"><nlm:aff id="aff91"><institution>Biocenter Kuopio, University of Eastern Finland</institution>
, Kuopio,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff93"><institution>School of Medicine, Institute of Clinical Medicine, Oncology, University of Eastern Finland</institution>
, Kuopio,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff94"><institution>Cancer Center, Kuopio University Hospital</institution>
, Kuopio,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kosma, V M" sort="Kosma, V M" uniqKey="Kosma V" first="V-M" last="Kosma">V-M Kosma</name>
<affiliation wicri:level="1"><nlm:aff id="aff90"><institution>School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland</institution>
, Kuopio,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff91"><institution>Biocenter Kuopio, University of Eastern Finland</institution>
, Kuopio,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff92"><institution>Department of Clinical Pathology, Kuopio University Hospital</institution>
, Kuopio,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hartikainen, J M" sort="Hartikainen, J M" uniqKey="Hartikainen J" first="J M" last="Hartikainen">J M Hartikainen</name>
<affiliation wicri:level="1"><nlm:aff id="aff90"><institution>School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland</institution>
, Kuopio,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff91"><institution>Biocenter Kuopio, University of Eastern Finland</institution>
, Kuopio,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff92"><institution>Department of Clinical Pathology, Kuopio University Hospital</institution>
, Kuopio,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lambrechts, D" sort="Lambrechts, D" uniqKey="Lambrechts D" first="D" last="Lambrechts">D. Lambrechts</name>
<affiliation wicri:level="1"><nlm:aff id="aff95"><institution>Vesalius Research Center (VRC), VIB</institution>
, Leuven,<country>Belgium</country>
</nlm:aff>
<country xml:lang="fr">Belgique</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Yesilyurt, B T" sort="Yesilyurt, B T" uniqKey="Yesilyurt B" first="B T" last="Yesilyurt">B T Yesilyurt</name>
<affiliation wicri:level="1"><nlm:aff id="aff95"><institution>Vesalius Research Center (VRC), VIB</institution>
, Leuven,<country>Belgium</country>
</nlm:aff>
<country xml:lang="fr">Belgique</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Floris, G" sort="Floris, G" uniqKey="Floris G" first="G" last="Floris">G. Floris</name>
<affiliation wicri:level="1"><nlm:aff id="aff96"><institution>Multidisciplinary Breast Center, University Hospital Gasthuisberg</institution>
, Leuven,<country>Belgium</country>
</nlm:aff>
<country xml:lang="fr">Belgique</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Leunen, K" sort="Leunen, K" uniqKey="Leunen K" first="K" last="Leunen">K. Leunen</name>
<affiliation wicri:level="1"><nlm:aff id="aff96"><institution>Multidisciplinary Breast Center, University Hospital Gasthuisberg</institution>
, Leuven,<country>Belgium</country>
</nlm:aff>
<country xml:lang="fr">Belgique</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Chang Claude, J" sort="Chang Claude, J" uniqKey="Chang Claude J" first="J" last="Chang-Claude">J. Chang-Claude</name>
<affiliation wicri:level="1"><nlm:aff id="aff97"><institution>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ)</institution>
, Heidelberg,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rudolph, A" sort="Rudolph, A" uniqKey="Rudolph A" first="A" last="Rudolph">A. Rudolph</name>
<affiliation wicri:level="1"><nlm:aff id="aff97"><institution>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ)</institution>
, Heidelberg,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Seibold, P" sort="Seibold, P" uniqKey="Seibold P" first="P" last="Seibold">P. Seibold</name>
<affiliation wicri:level="1"><nlm:aff id="aff97"><institution>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ)</institution>
, Heidelberg,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Flesch Janys, D" sort="Flesch Janys, D" uniqKey="Flesch Janys D" first="D" last="Flesch-Janys">D. Flesch-Janys</name>
<affiliation wicri:level="1"><nlm:aff id="aff98"><institution>Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf</institution>
, Hamburg,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff99"><institution>Department of Cancer Epidemiology/Clinical Cancer Registry, University Clinic Hamburg-Eppendorf</institution>
, Hamburg,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wang, X" sort="Wang, X" uniqKey="Wang X" first="X" last="Wang">X. Wang</name>
<affiliation wicri:level="1"><nlm:aff id="aff71"><institution>Department of Laboratory Medicine and Pathology, Mayo Clinic</institution>
, Rochester, MN,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Olson, J E" sort="Olson, J E" uniqKey="Olson J" first="J E" last="Olson">J E Olson</name>
<affiliation wicri:level="1"><nlm:aff id="aff100"><institution>Department of Health Sciences Research, Mayo Clinic</institution>
, Rochester, MN,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Vachon, C" sort="Vachon, C" uniqKey="Vachon C" first="C" last="Vachon">C. Vachon</name>
<affiliation wicri:level="1"><nlm:aff id="aff100"><institution>Department of Health Sciences Research, Mayo Clinic</institution>
, Rochester, MN,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Purrington, K" sort="Purrington, K" uniqKey="Purrington K" first="K" last="Purrington">K. Purrington</name>
<affiliation wicri:level="1"><nlm:aff id="aff100"><institution>Department of Health Sciences Research, Mayo Clinic</institution>
, Rochester, MN,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Giles, G G" sort="Giles, G G" uniqKey="Giles G" first="G G" last="Giles">G G Giles</name>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne</institution>
, Melbourne, Victoria,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff101"><institution>Cancer Epidemiology Centre, Cancer Council Victoria</institution>
, Melbourne,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Severi, G" sort="Severi, G" uniqKey="Severi G" first="G" last="Severi">G. Severi</name>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne</institution>
, Melbourne, Victoria,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff101"><institution>Cancer Epidemiology Centre, Cancer Council Victoria</institution>
, Melbourne,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Baglietto, L" sort="Baglietto, L" uniqKey="Baglietto L" first="L" last="Baglietto">L. Baglietto</name>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne</institution>
, Melbourne, Victoria,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff101"><institution>Cancer Epidemiology Centre, Cancer Council Victoria</institution>
, Melbourne,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Haiman, C A" sort="Haiman, C A" uniqKey="Haiman C" first="C A" last="Haiman">C A Haiman</name>
<affiliation wicri:level="1"><nlm:aff id="aff57"><institution>Department of Preventive Medicine, Keck School of Medicine, University of Southern California</institution>
, Los Angeles, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Henderson, B E" sort="Henderson, B E" uniqKey="Henderson B" first="B E" last="Henderson">B E Henderson</name>
<affiliation wicri:level="1"><nlm:aff id="aff57"><institution>Department of Preventive Medicine, Keck School of Medicine, University of Southern California</institution>
, Los Angeles, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schumacher, F" sort="Schumacher, F" uniqKey="Schumacher F" first="F" last="Schumacher">F. Schumacher</name>
<affiliation wicri:level="1"><nlm:aff id="aff57"><institution>Department of Preventive Medicine, Keck School of Medicine, University of Southern California</institution>
, Los Angeles, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Le Marchand, L" sort="Le Marchand, L" uniqKey="Le Marchand L" first="L" last="Le Marchand">L. Le Marchand</name>
<affiliation wicri:level="1"><nlm:aff id="aff102"><institution>University of Hawaii Cancer Center</institution>
, Honolulu, HI,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Simard, J" sort="Simard, J" uniqKey="Simard J" first="J" last="Simard">J. Simard</name>
<affiliation wicri:level="1"><nlm:aff id="aff103"><institution>Cancer Genomics Laboratory, Centre Hospitalier Universitaire de Quebec Research Center and Laval University</institution>
, Quebec,<country>Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Dumont, M" sort="Dumont, M" uniqKey="Dumont M" first="M" last="Dumont">M. Dumont</name>
<affiliation wicri:level="1"><nlm:aff id="aff103"><institution>Cancer Genomics Laboratory, Centre Hospitalier Universitaire de Quebec Research Center and Laval University</institution>
, Quebec,<country>Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Goldberg, M S" sort="Goldberg, M S" uniqKey="Goldberg M" first="M S" last="Goldberg">M S Goldberg</name>
<affiliation wicri:level="1"><nlm:aff id="aff104"><institution>Department of Medicine, McGill University, Montreal</institution>
, Montreal, Quebec,<country>Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff105"><institution>Division of Clinical Epidemiology, McGill University Health Centre, Royal Victoria Hospital</institution>
, Montreal, Quebec,<country>Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Labreche, F" sort="Labreche, F" uniqKey="Labreche F" first="F" last="Labrèche">F. Labrèche</name>
<affiliation wicri:level="1"><nlm:aff id="aff106"><institution>Département de médecine sociale et préventive, Département de santé environnementale et santé au travail, Université de Montréal</institution>
, Montreal, Quebec,<country>Canada</country>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Winqvist, R" sort="Winqvist, R" uniqKey="Winqvist R" first="R" last="Winqvist">R. Winqvist</name>
<affiliation wicri:level="1"><nlm:aff id="aff107"><institution>Laboratory of Cancer Genetics and Tumor Biology, Department of Clinical Chemistry and Biocenter Oulu, University of Oulu, Oulu University Hospital</institution>
, Oulu,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pylk S, K" sort="Pylk S, K" uniqKey="Pylk S K" first="K" last="Pylk S">K. Pylk S</name>
<affiliation wicri:level="1"><nlm:aff id="aff107"><institution>Laboratory of Cancer Genetics and Tumor Biology, Department of Clinical Chemistry and Biocenter Oulu, University of Oulu, Oulu University Hospital</institution>
, Oulu,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Jukkola Vuorinen, A" sort="Jukkola Vuorinen, A" uniqKey="Jukkola Vuorinen A" first="A" last="Jukkola-Vuorinen">A. Jukkola-Vuorinen</name>
<affiliation wicri:level="1"><nlm:aff id="aff108"><institution>Department of Oncology, Oulu University Hospital, University of Oulu</institution>
, Oulu,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Grip, M" sort="Grip, M" uniqKey="Grip M" first="M" last="Grip">M. Grip</name>
<affiliation wicri:level="1"><nlm:aff id="aff109"><institution>Department of Surgery, Oulu University Hospital, University of Oulu</institution>
, Oulu,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Devilee, P" sort="Devilee, P" uniqKey="Devilee P" first="P" last="Devilee">P. Devilee</name>
<affiliation wicri:level="1"><nlm:aff id="aff110"><institution>Department of Human Genetics, Leiden University Medical Center</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tollenaar, R A E M" sort="Tollenaar, R A E M" uniqKey="Tollenaar R" first="R A E M" last="Tollenaar">R A E M. Tollenaar</name>
<affiliation wicri:level="1"><nlm:aff id="aff111"><institution>Department of Surgical Oncology, Leiden University Medical Center</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Seynaeve, C" sort="Seynaeve, C" uniqKey="Seynaeve C" first="C" last="Seynaeve">C. Seynaeve</name>
<affiliation wicri:level="1"><nlm:aff id="aff112"><institution>Department of Medical Oncology, Family Cancer Clinic, Erasmus University Medical Centre</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Garcia Closas, M" sort="Garcia Closas, M" uniqKey="Garcia Closas M" first="M" last="García-Closas">M. García-Closas</name>
<affiliation wicri:level="1"><nlm:aff id="aff13"><institution>Division of Breast Cancer Research, The Institute of Cancer Research</institution>
, London,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff113"><institution>Division of Cancer Epidemiology and Genetics, National Cancer Institute</institution>
, Rockville, MD,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff114"><institution>Division of Genetics and Epidemiology, Institute of Cancer Research and Breakthrough Breast Cancer Research Centre</institution>
, London,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Chanock, S J" sort="Chanock, S J" uniqKey="Chanock S" first="S J" last="Chanock">S J Chanock</name>
<affiliation wicri:level="1"><nlm:aff id="aff113"><institution>Division of Cancer Epidemiology and Genetics, National Cancer Institute</institution>
, Rockville, MD,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lissowska, J" sort="Lissowska, J" uniqKey="Lissowska J" first="J" last="Lissowska">J. Lissowska</name>
<affiliation wicri:level="1"><nlm:aff id="aff115"><institution>Department of Cancer Epidemiology and Prevention, M. Sklodowska-Curie Memorial Cancer Center & Institute of Oncology</institution>
, Warsaw,<country>Poland</country>
</nlm:aff>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Figueroa, J D" sort="Figueroa, J D" uniqKey="Figueroa J" first="J D" last="Figueroa">J D Figueroa</name>
<affiliation wicri:level="1"><nlm:aff id="aff113"><institution>Division of Cancer Epidemiology and Genetics, National Cancer Institute</institution>
, Rockville, MD,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Czene, K" sort="Czene, K" uniqKey="Czene K" first="K" last="Czene">K. Czene</name>
<affiliation wicri:level="1"><nlm:aff id="aff116"><institution>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet</institution>
, Stockholm,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Eriksson, M" sort="Eriksson, M" uniqKey="Eriksson M" first="M" last="Eriksson">M. Eriksson</name>
<affiliation wicri:level="1"><nlm:aff id="aff116"><institution>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet</institution>
, Stockholm,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Humphreys, K" sort="Humphreys, K" uniqKey="Humphreys K" first="K" last="Humphreys">K. Humphreys</name>
<affiliation wicri:level="1"><nlm:aff id="aff116"><institution>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet</institution>
, Stockholm,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Darabi, H" sort="Darabi, H" uniqKey="Darabi H" first="H" last="Darabi">H. Darabi</name>
<affiliation wicri:level="1"><nlm:aff id="aff116"><institution>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet</institution>
, Stockholm,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hooning, M J" sort="Hooning, M J" uniqKey="Hooning M" first="M J" last="Hooning">M J Hooning</name>
<affiliation wicri:level="1"><nlm:aff id="aff112"><institution>Department of Medical Oncology, Family Cancer Clinic, Erasmus University Medical Centre</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kriege, M" sort="Kriege, M" uniqKey="Kriege M" first="M" last="Kriege">M. Kriege</name>
<affiliation wicri:level="1"><nlm:aff id="aff112"><institution>Department of Medical Oncology, Family Cancer Clinic, Erasmus University Medical Centre</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Collee, J M" sort="Collee, J M" uniqKey="Collee J" first="J M" last="Collée">J M Collée</name>
<affiliation wicri:level="1"><nlm:aff id="aff117"><institution>Department of Clinical Genetics, Family Cancer Clinic, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tilanus Linthorst, M" sort="Tilanus Linthorst, M" uniqKey="Tilanus Linthorst M" first="M" last="Tilanus-Linthorst">M. Tilanus-Linthorst</name>
<affiliation wicri:level="1"><nlm:aff id="aff118"><institution>Department of Surgical Oncology, Family Cancer Clinic, Erasmus University Medical Centre</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Li, J" sort="Li, J" uniqKey="Li J" first="J" last="Li">J. Li</name>
<affiliation wicri:level="1"><nlm:aff id="aff119"><institution>Human Genetics Division, Genome Institute of Singapore</institution>
, Singapore,<country>Singapore</country>
</nlm:aff>
<country xml:lang="fr">Singapour</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Jakubowska, A" sort="Jakubowska, A" uniqKey="Jakubowska A" first="A" last="Jakubowska">A. Jakubowska</name>
<affiliation wicri:level="1"><nlm:aff id="aff120"><institution>Department of Genetics and Pathology, Pomeranian Medical University</institution>
, Szczecin,<country>Poland</country>
</nlm:aff>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lubinski, J" sort="Lubinski, J" uniqKey="Lubinski J" first="J" last="Lubinski">J. Lubinski</name>
<affiliation wicri:level="1"><nlm:aff id="aff120"><institution>Department of Genetics and Pathology, Pomeranian Medical University</institution>
, Szczecin,<country>Poland</country>
</nlm:aff>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Jaworska Bieniek, K" sort="Jaworska Bieniek, K" uniqKey="Jaworska Bieniek K" first="K" last="Jaworska-Bieniek">K. Jaworska-Bieniek</name>
<affiliation wicri:level="1"><nlm:aff id="aff120"><institution>Department of Genetics and Pathology, Pomeranian Medical University</institution>
, Szczecin,<country>Poland</country>
</nlm:aff>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Durda, K" sort="Durda, K" uniqKey="Durda K" first="K" last="Durda">K. Durda</name>
<affiliation wicri:level="1"><nlm:aff id="aff120"><institution>Department of Genetics and Pathology, Pomeranian Medical University</institution>
, Szczecin,<country>Poland</country>
</nlm:aff>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Nevanlinna, H" sort="Nevanlinna, H" uniqKey="Nevanlinna H" first="H" last="Nevanlinna">H. Nevanlinna</name>
<affiliation wicri:level="1"><nlm:aff id="aff121"><institution>Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Muranen, T A" sort="Muranen, T A" uniqKey="Muranen T" first="T A" last="Muranen">T A Muranen</name>
<affiliation wicri:level="1"><nlm:aff id="aff121"><institution>Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Aittom Ki, K" sort="Aittom Ki, K" uniqKey="Aittom Ki K" first="K" last="Aittom Ki">K. Aittom Ki</name>
<affiliation wicri:level="1"><nlm:aff id="aff122"><institution>Department of Clinical Genetics, Helsinki University Central Hospital</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Blomqvist, C" sort="Blomqvist, C" uniqKey="Blomqvist C" first="C" last="Blomqvist">C. Blomqvist</name>
<affiliation wicri:level="1"><nlm:aff id="aff123"><institution>Department of Oncology, Helsinki University Central Hospital</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bogdanova, N" sort="Bogdanova, N" uniqKey="Bogdanova N" first="N" last="Bogdanova">N. Bogdanova</name>
<affiliation wicri:level="1"><nlm:aff id="aff124"><institution>Department of Obstetrics and Gynaecology, Hannover Medical School</institution>
, Hannover,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff125"><institution>Department of Radiation Oncology, Hannover Medical School</institution>
, Hannover,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Dork, T" sort="Dork, T" uniqKey="Dork T" first="T" last="Dörk">T. Dörk</name>
<affiliation wicri:level="1"><nlm:aff id="aff124"><institution>Department of Obstetrics and Gynaecology, Hannover Medical School</institution>
, Hannover,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hall, P" sort="Hall, P" uniqKey="Hall P" first="P" last="Hall">P. Hall</name>
<affiliation wicri:level="1"><nlm:aff id="aff116"><institution>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet</institution>
, Stockholm,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Chenevix Trench, G" sort="Chenevix Trench, G" uniqKey="Chenevix Trench G" first="G" last="Chenevix-Trench">G. Chenevix-Trench</name>
<affiliation wicri:level="1"><nlm:aff id="aff19"><institution>QIMR Berghofer Institute of Medical Research</institution>
, Brisbane, Queensland,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Easton, D F" sort="Easton, D F" uniqKey="Easton D" first="D F" last="Easton">D F Easton</name>
<affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge</institution>
, Cambridge,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff42"><institution>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge</institution>
, Cambridge,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pharoah, P D P" sort="Pharoah, P D P" uniqKey="Pharoah P" first="P D P" last="Pharoah">P D P. Pharoah</name>
<affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge</institution>
, Cambridge,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff42"><institution>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge</institution>
, Cambridge,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Arias Perez, J I" sort="Arias Perez, J I" uniqKey="Arias Perez J" first="J I" last="Arias-Perez">J I Arias-Perez</name>
<affiliation wicri:level="1"><nlm:aff id="aff126"><institution>Servicio de Cirugía General y Especialidades, Hospital Monte Naranco</institution>
, Oviedo,<country>Spain</country>
</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Zamora, P" sort="Zamora, P" uniqKey="Zamora P" first="P" last="Zamora">P. Zamora</name>
<affiliation wicri:level="1"><nlm:aff id="aff127"><institution>Servicio de Oncología Médica, Hospital Universitario La Paz</institution>
, Madrid,<country>Spain</country>
</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Benitez, J" sort="Benitez, J" uniqKey="Benitez J" first="J" last="Benítez">J. Benítez</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO)</institution>
, Madrid,<country>Spain</country>
</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff5"><institution>Human Genotyping-CEGEN Unit, Spanish National Cancer Research Centre (CNIO)</institution>
, Madrid,<country>Spain</country>
</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Milne, R L" sort="Milne, R L" uniqKey="Milne R" first="R L" last="Milne">R L Milne</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO)</institution>
, Madrid,<country>Spain</country>
</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne</institution>
, Melbourne, Victoria,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff101"><institution>Cancer Epidemiology Centre, Cancer Council Victoria</institution>
, Melbourne,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
</analytic>
<series><title level="j">British Journal of Cancer</title>
<idno type="ISSN">0007-0920</idno>
<idno type="eISSN">1532-1827</idno>
<imprint><date when="2014">2014</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><sec><title>Background:</title>
<p>Breast cancer is one of the most common malignancies in women. Genome-wide association studies have identified <italic>FGFR2</italic>
as a breast cancer susceptibility gene. Common variation in other fibroblast growth factor (FGF) receptors might also modify risk. We tested this hypothesis by studying genotyped single-nucleotide polymorphisms (SNPs) and imputed SNPs in <italic>FGFR1, FGFR3, FGFR4</italic>
and <italic>FGFRL1</italic>
in the Breast Cancer Association Consortium.</p>
</sec>
<sec><title>Methods:</title>
<p>Data were combined from 49 studies, including 53 835 cases and 50 156 controls, of which 89 050 (46 450 cases and 42 600 controls) were of European ancestry, 12 893 (6269 cases and 6624 controls) of Asian and 2048 (1116 cases and 932 controls) of African ancestry. Associations with risk of breast cancer, overall and by disease sub-type, were assessed using unconditional logistic regression.</p>
</sec>
<sec><title>Results:</title>
<p>Little evidence of association with breast cancer risk was observed for SNPs in the FGF receptor genes. The strongest evidence in European women was for rs743682 in <italic>FGFR3</italic>
; the estimated per-allele odds ratio was 1.05 (95% confidence interval=1.02–1.09, <italic>P=</italic>
0.0020), which is substantially lower than that observed for SNPs in <italic>FGFR2.</italic>
</p>
</sec>
<sec><title>Conclusion:</title>
<p>Our results suggest that common variants in the other FGF receptors are not associated with risk of breast cancer to the degree observed for <italic>FGFR2</italic>
.</p>
</sec>
</div>
</front>
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<article-id pub-id-type="pmc">3929867</article-id>
<article-id pub-id-type="pii">bjc2013769</article-id>
<article-id pub-id-type="doi">10.1038/bjc.2013.769</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Genetics and Genomics</subject>
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<contrib contrib-type="author"><name><surname>Brock</surname>
<given-names>I W</given-names>
</name>
<xref ref-type="aff" rid="aff58">58</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Reed</surname>
<given-names>M W R</given-names>
</name>
<xref ref-type="aff" rid="aff58">58</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Muir</surname>
<given-names>K</given-names>
</name>
<xref ref-type="aff" rid="aff59">59</xref>
<xref ref-type="aff" rid="aff60">60</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Lophatananon</surname>
<given-names>A</given-names>
</name>
<xref ref-type="aff" rid="aff60">60</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Stewart-Brown</surname>
<given-names>S</given-names>
</name>
<xref ref-type="aff" rid="aff60">60</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Siriwanarangsan</surname>
<given-names>P</given-names>
</name>
<xref ref-type="aff" rid="aff61">61</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Zheng</surname>
<given-names>W</given-names>
</name>
<xref ref-type="aff" rid="aff62">62</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Deming-Halverson</surname>
<given-names>S</given-names>
</name>
<xref ref-type="aff" rid="aff62">62</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Shrubsole</surname>
<given-names>M J</given-names>
</name>
<xref ref-type="aff" rid="aff62">62</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Long</surname>
<given-names>J</given-names>
</name>
<xref ref-type="aff" rid="aff62">62</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Shu</surname>
<given-names>X-O</given-names>
</name>
<xref ref-type="aff" rid="aff62">62</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Lu</surname>
<given-names>W</given-names>
</name>
<xref ref-type="aff" rid="aff63">63</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Gao</surname>
<given-names>Y-T</given-names>
</name>
<xref ref-type="aff" rid="aff64">64</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Zhang</surname>
<given-names>B</given-names>
</name>
<xref ref-type="aff" rid="aff62">62</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Radice</surname>
<given-names>P</given-names>
</name>
<xref ref-type="aff" rid="aff65">65</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Peterlongo</surname>
<given-names>P</given-names>
</name>
<xref ref-type="aff" rid="aff66">66</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Manoukian</surname>
<given-names>S</given-names>
</name>
<xref ref-type="aff" rid="aff67">67</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Mariette</surname>
<given-names>F</given-names>
</name>
<xref ref-type="aff" rid="aff66">66</xref>
<xref ref-type="aff" rid="aff68">68</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Sangrajrang</surname>
<given-names>S</given-names>
</name>
<xref ref-type="aff" rid="aff69">69</xref>
</contrib>
<contrib contrib-type="author"><name><surname>McKay</surname>
<given-names>J</given-names>
</name>
<xref ref-type="aff" rid="aff70">70</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Couch</surname>
<given-names>F J</given-names>
</name>
<xref ref-type="aff" rid="aff71">71</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Toland</surname>
<given-names>A E</given-names>
</name>
<xref ref-type="aff" rid="aff72">72</xref>
</contrib>
<contrib contrib-type="author"><collab>TNBCC<xref ref-type="aff" rid="aff73">73</xref>
</collab>
</contrib>
<contrib contrib-type="author"><name><surname>Yannoukakos</surname>
<given-names>D</given-names>
</name>
<xref ref-type="aff" rid="aff74">74</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Fletcher</surname>
<given-names>O</given-names>
</name>
<xref ref-type="aff" rid="aff75">75</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Johnson</surname>
<given-names>N</given-names>
</name>
<xref ref-type="aff" rid="aff75">75</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Silva</surname>
<given-names>I dos Santos</given-names>
</name>
<xref ref-type="aff" rid="aff76">76</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Peto</surname>
<given-names>J</given-names>
</name>
<xref ref-type="aff" rid="aff76">76</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Marme</surname>
<given-names>F</given-names>
</name>
<xref ref-type="aff" rid="aff77">77</xref>
<xref ref-type="aff" rid="aff78">78</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Burwinkel</surname>
<given-names>B</given-names>
</name>
<xref ref-type="aff" rid="aff77">77</xref>
<xref ref-type="aff" rid="aff79">79</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Guénel</surname>
<given-names>P</given-names>
</name>
<xref ref-type="aff" rid="aff80">80</xref>
<xref ref-type="aff" rid="aff81">81</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Truong</surname>
<given-names>T</given-names>
</name>
<xref ref-type="aff" rid="aff80">80</xref>
<xref ref-type="aff" rid="aff81">81</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Sanchez</surname>
<given-names>M</given-names>
</name>
<xref ref-type="aff" rid="aff80">80</xref>
<xref ref-type="aff" rid="aff81">81</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Mulot</surname>
<given-names>C</given-names>
</name>
<xref ref-type="aff" rid="aff82">82</xref>
<xref ref-type="aff" rid="aff83">83</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Bojesen</surname>
<given-names>S E</given-names>
</name>
<xref ref-type="aff" rid="aff84">84</xref>
<xref ref-type="aff" rid="aff85">85</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Nordestgaard</surname>
<given-names>B G</given-names>
</name>
<xref ref-type="aff" rid="aff84">84</xref>
<xref ref-type="aff" rid="aff85">85</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Flyer</surname>
<given-names>H</given-names>
</name>
<xref ref-type="aff" rid="aff86">86</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Brenner</surname>
<given-names>H</given-names>
</name>
<xref ref-type="aff" rid="aff87">87</xref>
<xref ref-type="aff" rid="aff88">88</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Dieffenbach</surname>
<given-names>A K</given-names>
</name>
<xref ref-type="aff" rid="aff87">87</xref>
<xref ref-type="aff" rid="aff88">88</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Arndt</surname>
<given-names>V</given-names>
</name>
<xref ref-type="aff" rid="aff87">87</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Stegmaier</surname>
<given-names>C</given-names>
</name>
<xref ref-type="aff" rid="aff89">89</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Mannermaa</surname>
<given-names>A</given-names>
</name>
<xref ref-type="aff" rid="aff90">90</xref>
<xref ref-type="aff" rid="aff91">91</xref>
<xref ref-type="aff" rid="aff92">92</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kataja</surname>
<given-names>V</given-names>
</name>
<xref ref-type="aff" rid="aff91">91</xref>
<xref ref-type="aff" rid="aff93">93</xref>
<xref ref-type="aff" rid="aff94">94</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kosma</surname>
<given-names>V-M</given-names>
</name>
<xref ref-type="aff" rid="aff90">90</xref>
<xref ref-type="aff" rid="aff91">91</xref>
<xref ref-type="aff" rid="aff92">92</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Hartikainen</surname>
<given-names>J M</given-names>
</name>
<xref ref-type="aff" rid="aff90">90</xref>
<xref ref-type="aff" rid="aff91">91</xref>
<xref ref-type="aff" rid="aff92">92</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Lambrechts</surname>
<given-names>D</given-names>
</name>
<xref ref-type="aff" rid="aff95">95</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Yesilyurt</surname>
<given-names>B T</given-names>
</name>
<xref ref-type="aff" rid="aff95">95</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Floris</surname>
<given-names>G</given-names>
</name>
<xref ref-type="aff" rid="aff96">96</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Leunen</surname>
<given-names>K</given-names>
</name>
<xref ref-type="aff" rid="aff96">96</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Chang-Claude</surname>
<given-names>J</given-names>
</name>
<xref ref-type="aff" rid="aff97">97</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Rudolph</surname>
<given-names>A</given-names>
</name>
<xref ref-type="aff" rid="aff97">97</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Seibold</surname>
<given-names>P</given-names>
</name>
<xref ref-type="aff" rid="aff97">97</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Flesch-Janys</surname>
<given-names>D</given-names>
</name>
<xref ref-type="aff" rid="aff98">98</xref>
<xref ref-type="aff" rid="aff99">99</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Wang</surname>
<given-names>X</given-names>
</name>
<xref ref-type="aff" rid="aff71">71</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Olson</surname>
<given-names>J E</given-names>
</name>
<xref ref-type="aff" rid="aff100">100</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Vachon</surname>
<given-names>C</given-names>
</name>
<xref ref-type="aff" rid="aff100">100</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Purrington</surname>
<given-names>K</given-names>
</name>
<xref ref-type="aff" rid="aff100">100</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Giles</surname>
<given-names>G G</given-names>
</name>
<xref ref-type="aff" rid="aff30">30</xref>
<xref ref-type="aff" rid="aff101">101</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Severi</surname>
<given-names>G</given-names>
</name>
<xref ref-type="aff" rid="aff30">30</xref>
<xref ref-type="aff" rid="aff101">101</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Baglietto</surname>
<given-names>L</given-names>
</name>
<xref ref-type="aff" rid="aff30">30</xref>
<xref ref-type="aff" rid="aff101">101</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Haiman</surname>
<given-names>C A</given-names>
</name>
<xref ref-type="aff" rid="aff57">57</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Henderson</surname>
<given-names>B E</given-names>
</name>
<xref ref-type="aff" rid="aff57">57</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Schumacher</surname>
<given-names>F</given-names>
</name>
<xref ref-type="aff" rid="aff57">57</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Le Marchand</surname>
<given-names>L</given-names>
</name>
<xref ref-type="aff" rid="aff102">102</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Simard</surname>
<given-names>J</given-names>
</name>
<xref ref-type="aff" rid="aff103">103</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Dumont</surname>
<given-names>M</given-names>
</name>
<xref ref-type="aff" rid="aff103">103</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Goldberg</surname>
<given-names>M S</given-names>
</name>
<xref ref-type="aff" rid="aff104">104</xref>
<xref ref-type="aff" rid="aff105">105</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Labrèche</surname>
<given-names>F</given-names>
</name>
<xref ref-type="aff" rid="aff106">106</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Winqvist</surname>
<given-names>R</given-names>
</name>
<xref ref-type="aff" rid="aff107">107</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Pylkäs</surname>
<given-names>K</given-names>
</name>
<xref ref-type="aff" rid="aff107">107</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Jukkola-Vuorinen</surname>
<given-names>A</given-names>
</name>
<xref ref-type="aff" rid="aff108">108</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Grip</surname>
<given-names>M</given-names>
</name>
<xref ref-type="aff" rid="aff109">109</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Devilee</surname>
<given-names>P</given-names>
</name>
<xref ref-type="aff" rid="aff110">110</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Tollenaar</surname>
<given-names>R A E M</given-names>
</name>
<xref ref-type="aff" rid="aff111">111</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Seynaeve</surname>
<given-names>C</given-names>
</name>
<xref ref-type="aff" rid="aff112">112</xref>
</contrib>
<contrib contrib-type="author"><name><surname>García-Closas</surname>
<given-names>M</given-names>
</name>
<xref ref-type="aff" rid="aff13">13</xref>
<xref ref-type="aff" rid="aff113">113</xref>
<xref ref-type="aff" rid="aff114">114</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Chanock</surname>
<given-names>S J</given-names>
</name>
<xref ref-type="aff" rid="aff113">113</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Lissowska</surname>
<given-names>J</given-names>
</name>
<xref ref-type="aff" rid="aff115">115</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Figueroa</surname>
<given-names>J D</given-names>
</name>
<xref ref-type="aff" rid="aff113">113</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Czene</surname>
<given-names>K</given-names>
</name>
<xref ref-type="aff" rid="aff116">116</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Eriksson</surname>
<given-names>M</given-names>
</name>
<xref ref-type="aff" rid="aff116">116</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Humphreys</surname>
<given-names>K</given-names>
</name>
<xref ref-type="aff" rid="aff116">116</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Darabi</surname>
<given-names>H</given-names>
</name>
<xref ref-type="aff" rid="aff116">116</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Hooning</surname>
<given-names>M J</given-names>
</name>
<xref ref-type="aff" rid="aff112">112</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kriege</surname>
<given-names>M</given-names>
</name>
<xref ref-type="aff" rid="aff112">112</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Collée</surname>
<given-names>J M</given-names>
</name>
<xref ref-type="aff" rid="aff117">117</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Tilanus-Linthorst</surname>
<given-names>M</given-names>
</name>
<xref ref-type="aff" rid="aff118">118</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Li</surname>
<given-names>J</given-names>
</name>
<xref ref-type="aff" rid="aff119">119</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Jakubowska</surname>
<given-names>A</given-names>
</name>
<xref ref-type="aff" rid="aff120">120</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Lubinski</surname>
<given-names>J</given-names>
</name>
<xref ref-type="aff" rid="aff120">120</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Jaworska-Bieniek</surname>
<given-names>K</given-names>
</name>
<xref ref-type="aff" rid="aff120">120</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Durda</surname>
<given-names>K</given-names>
</name>
<xref ref-type="aff" rid="aff120">120</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Nevanlinna</surname>
<given-names>H</given-names>
</name>
<xref ref-type="aff" rid="aff121">121</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Muranen</surname>
<given-names>T A</given-names>
</name>
<xref ref-type="aff" rid="aff121">121</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Aittomäki</surname>
<given-names>K</given-names>
</name>
<xref ref-type="aff" rid="aff122">122</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Blomqvist</surname>
<given-names>C</given-names>
</name>
<xref ref-type="aff" rid="aff123">123</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Bogdanova</surname>
<given-names>N</given-names>
</name>
<xref ref-type="aff" rid="aff124">124</xref>
<xref ref-type="aff" rid="aff125">125</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Dörk</surname>
<given-names>T</given-names>
</name>
<xref ref-type="aff" rid="aff124">124</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Hall</surname>
<given-names>P</given-names>
</name>
<xref ref-type="aff" rid="aff116">116</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Chenevix-Trench</surname>
<given-names>G</given-names>
</name>
<xref ref-type="aff" rid="aff19">19</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Easton</surname>
<given-names>D F</given-names>
</name>
<xref ref-type="aff" rid="aff3">3</xref>
<xref ref-type="aff" rid="aff42">42</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Pharoah</surname>
<given-names>P D P</given-names>
</name>
<xref ref-type="aff" rid="aff3">3</xref>
<xref ref-type="aff" rid="aff42">42</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Arias-Perez</surname>
<given-names>J I</given-names>
</name>
<xref ref-type="aff" rid="aff126">126</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Zamora</surname>
<given-names>P</given-names>
</name>
<xref ref-type="aff" rid="aff127">127</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Benítez</surname>
<given-names>J</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
<xref ref-type="aff" rid="aff5">5</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Milne</surname>
<given-names>R L</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
<xref ref-type="aff" rid="aff30">30</xref>
<xref ref-type="aff" rid="aff101">101</xref>
<xref ref-type="corresp" rid="caf1">*</xref>
</contrib>
<aff id="aff1"><label>1</label>
<institution>Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO)</institution>
, Madrid,<country>Spain</country>
</aff>
<aff id="aff2"><label>2</label>
<institution>Department of Molecular, Cellular and Developmental Biology, Yale University</institution>
, New Haven, CT,<country>USA</country>
</aff>
<aff id="aff3"><label>3</label>
<institution>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge</institution>
, Cambridge,<country>UK</country>
</aff>
<aff id="aff4"><label>4</label>
<institution>Biostatistics Unit, IMDEA Food Institute</institution>
, Madrid,<country>Spain</country>
</aff>
<aff id="aff5"><label>5</label>
<institution>Human Genotyping-CEGEN Unit, Spanish National Cancer Research Centre (CNIO)</institution>
, Madrid,<country>Spain</country>
</aff>
<aff id="aff6"><label>6</label>
<institution>CRUK Cambridge Institute, University of Cambridge</institution>
, Cambridge,<country>UK</country>
</aff>
<aff id="aff7"><label>7</label>
<institution>Hospital Monte Naranco</institution>
, Oviedo,<country>Spain</country>
</aff>
<aff id="aff8"><label>8</label>
<institution>Department of Pathology, Hospital Universitario La Paz, IdiPAZ (Hospital La Paz Institute for Health Research) Universidad Autonoma de Madrid</institution>
, Madrid,<country>Spain</country>
</aff>
<aff id="aff9"><label>9</label>
<institution>Laboratory of Pathology and Oncology, Research Unit, Hospital Universitario La Paz, IdiPAZ</institution>
, Madrid,<country>Spain</country>
</aff>
<aff id="aff10"><label>10</label>
<institution>Department of Molecular Medicine and Surgery, Karolinska Institutet</institution>
, Stockholm,<country>Sweden</country>
</aff>
<aff id="aff11"><label>11</label>
<institution>Department of Oncology—Pathology, Karolinska Institutet</institution>
, Stockholm,<country>Sweden</country>
</aff>
<aff id="aff12"><label>12</label>
<institution>Division of Genetics and Epidemiology, The Institute of Cancer Research</institution>
, Sutton,<country>UK</country>
</aff>
<aff id="aff13"><label>13</label>
<institution>Division of Breast Cancer Research, The Institute of Cancer Research</institution>
, London,<country>UK</country>
</aff>
<aff id="aff14"><label>14</label>
<institution>Breakthrough Breast Cancer Research Centre, Division of Breast Cancer Research, The Institute of Cancer Research</institution>
, London,<country>UK</country>
</aff>
<aff id="aff15"><label>15</label>
<institution>Department of Preventive Medicine, Kyushu University Faculty of Medical Sciences</institution>
, Fukuoka,<country>Japan</country>
</aff>
<aff id="aff16"><label>16</label>
<institution>Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute</institution>
, Nagoya,<country>Japan</country>
</aff>
<aff id="aff17"><label>17</label>
<institution>Department of Breast Oncology, Aichi Cancer Center Hospital</institution>
, Nagoya,<country>Japan</country>
</aff>
<aff id="aff18"><label>18</label>
<institution>Peter MacCallum Cancer Centre</institution>
, Melbourne, Victoria,<country>Australia</country>
</aff>
<aff id="aff19"><label>19</label>
<institution>QIMR Berghofer Institute of Medical Research</institution>
, Brisbane, Queensland,<country>Australia</country>
</aff>
<aff id="aff20"><label>20</label>
<institution>Saw Swee Hock School of Public Health, Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System</institution>
, Singapore,<country>Singapore</country>
</aff>
<aff id="aff21"><label>21</label>
<institution>Saw Swee Hock School of Public Health, National University of Singapore and National University Health System</institution>
, Singapore,<country>Singapore</country>
</aff>
<aff id="aff22"><label>22</label>
<institution>Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System</institution>
, Singapore,<country>Singapore</country>
</aff>
<aff id="aff23"><label>23</label>
<institution>Research Oncology, Division of Cancer Studies, Kings College London Guy's Hospital</institution>
, London,<country>UK</country>
</aff>
<aff id="aff24"><label>24</label>
<institution>Wellcome Trust Centre for Human Genetics, University of Oxford</institution>
, Oxford,<country>UK</country>
</aff>
<aff id="aff25"><label>25</label>
<institution>Oxford Biomedical Research Centre, University of Oxford</institution>
, Oxford,<country>UK</country>
</aff>
<aff id="aff26"><label>26</label>
<institution>School of Medicine, Clinical Science Institute, National University of Ireland</institution>
, Galway,<country>UK</country>
</aff>
<aff id="aff27"><label>27</label>
<institution>Department of Preventive Medicine, Seoul National University College of Medicine</institution>
, Seoul,<country>Korea</country>
</aff>
<aff id="aff28"><label>28</label>
<institution>Department of Biomedical Sciences, Seoul National University Graduate School</institution>
, Seoul,<country>Korea</country>
</aff>
<aff id="aff29"><label>29</label>
<institution>Department of Surgery, Seoul National University College of Medicine</institution>
, Seoul,<country>Korea</country>
</aff>
<aff id="aff30"><label>30</label>
<institution>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne</institution>
, Melbourne, Victoria,<country>Australia</country>
</aff>
<aff id="aff31"><label>31</label>
<institution>Department of Pathology, University of Melbourne</institution>
, Melbourne, Victoria,<country>Australia</country>
</aff>
<aff id="aff32"><label>32</label>
<institution>Cancer Research Initiatives Foundation, Sime Darby Medical Centre</institution>
, Subang Jaya,<country>Malaysia</country>
</aff>
<aff id="aff33"><label>33</label>
<institution>Breast Cancer Research Unit, University Malaya Cancer Research Institute, University Malaya Medical Centre</institution>
, Kuala Lumpur,<country>Malaysia</country>
</aff>
<aff id="aff34"><label>34</label>
<institution>Singapore Eye Research Institute, National University of Singapore</institution>
,<country>Singapore</country>
</aff>
<aff id="aff35"><label>35</label>
<institution>Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology</institution>
, Stuttgart,<country>Germany</country>
</aff>
<aff id="aff36"><label>36</label>
<institution>University of Tübingen</institution>
,<country>Germany</country>
</aff>
<aff id="aff37"><label>37</label>
<institution>Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-University Bochum (IPA)</institution>
,<country>Germany</country>
</aff>
<aff id="aff38"><label>38</label>
<institution>Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg</institution>
,<country>Germany</country>
</aff>
<aff id="aff39"><label>39</label>
<institution>Institute for Occupational Medicine and Maritime Medicine, University Medical Center Hamburg-Eppendorf</institution>
,<country>Germany</country>
</aff>
<aff id="aff40"><label>40</label>
<institution>Institute of Pathology, Medical Faculty of the University of Bonn</institution>
,<country>Germany</country>
</aff>
<aff id="aff41"><label>41</label>
<institution>Department of Internal Medicine, Evangelische Kliniken Bonn GmbH, Johanniter Krankenhaus, Bonn</institution>
,<country>Germany</country>
</aff>
<aff id="aff42"><label>42</label>
<institution>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge</institution>
, Cambridge,<country>UK</country>
</aff>
<aff id="aff43"><label>43</label>
<institution>Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital</institution>
, Toronto, Ontario,<country>Canada</country>
</aff>
<aff id="aff44"><label>44</label>
<institution>Department of Molecular Genetics, University of Toronto</institution>
, Toronto, Ontario,<country>Canada</country>
</aff>
<aff id="aff45"><label>45</label>
<institution>Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto</institution>
, Toronto, Ontario,<country>Canada</country>
</aff>
<aff id="aff46"><label>46</label>
<institution>Ontario Cancer Genetics Network, Lunenfeld-Tanenbaum Research Institute</institution>
, Toronto, Ontario,<country>Canada</country>
</aff>
<aff id="aff47"><label>47</label>
<institution>Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital</institution>
, Amsterdam,<country>The Netherlands</country>
</aff>
<aff id="aff48"><label>48</label>
<institution>Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN</institution>
, Erlangen,<country>Germany</country>
</aff>
<aff id="aff49"><label>49</label>
<institution>David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology, University of California at Los Angeles</institution>
, CA,<country>USA</country>
</aff>
<aff id="aff50"><label>50</label>
<institution>Institute of Human Genetics, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg</institution>
, Erlangen,<country>Germany</country>
</aff>
<aff id="aff51"><label>51</label>
<institution>Institute of Biomedical Sciences, Academia Sinica</institution>
, Taipei,<country>Taiwan</country>
</aff>
<aff id="aff52"><label>52</label>
<institution>College of Public Health, China Medical University</institution>
, Taichong,<country>Taiwan</country>
</aff>
<aff id="aff53"><label>53</label>
<institution>Tri-Service General Hospital</institution>
, Taipei,<country>Taiwan</country>
</aff>
<aff id="aff54"><label>54</label>
<institution>Cancer Center, Kaohsiung Medical University Chung-Ho Memorial Hospital</institution>
, Kaohsiung,<country>Taiwan</country>
</aff>
<aff id="aff55"><label>55</label>
<institution>Department of Surgery, Kaohsiung Medical University Chung-Ho Memorial Hospital</institution>
, Kaohsiung,<country>Taiwan</country>
</aff>
<aff id="aff56"><label>56</label>
<institution>Department of Medicine, Vanderbilt University</institution>
, Nashville,<country>TN USA</country>
</aff>
<aff id="aff57"><label>57</label>
<institution>Department of Preventive Medicine, Keck School of Medicine, University of Southern California</institution>
, Los Angeles, CA,<country>USA</country>
</aff>
<aff id="aff58"><label>58</label>
<institution>CRUK/YCR Sheffield Cancer Research Centre, Department of Oncology, University of Sheffield</institution>
, Sheffield,<country>UK</country>
</aff>
<aff id="aff59"><label>59</label>
<institution>Institute of Population Health, University of Manchester</institution>
, Manchester,<country>UK</country>
</aff>
<aff id="aff60"><label>60</label>
<institution>Division of Health Sciences, Warwick Medical School</institution>
, Coventry,<country>UK</country>
</aff>
<aff id="aff61"><label>61</label>
<institution>Ministry of Public Health</institution>
, Bangkok,<country>Thailand</country>
</aff>
<aff id="aff62"><label>62</label>
<institution>Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center</institution>
, Nashville, TN,<country>USA</country>
</aff>
<aff id="aff63"><label>63</label>
<institution>Shanghai Center for Disease Control and Prevention</institution>
, Shanghai,<country>China</country>
</aff>
<aff id="aff64"><label>64</label>
<institution>Shanghai Cancer Institute</institution>
, Shanghai,<country>China</country>
</aff>
<aff id="aff65"><label>65</label>
<institution>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori (INT)</institution>
, Milan,<country>Italy</country>
</aff>
<aff id="aff66"><label>66</label>
<institution>IFOM, Fondazione Istituto FIRC di Oncologia Molecolare</institution>
, Milan,<country>Italy</country>
</aff>
<aff id="aff67"><label>67</label>
<institution>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori (INT)</institution>
, Milan,<country>Italy</country>
</aff>
<aff id="aff68"><label>68</label>
<institution>Cogentech Cancer Genetic Test Laboratory</institution>
, Milan,<country>Italy</country>
</aff>
<aff id="aff69"><label>69</label>
<institution>National Cancer Institute</institution>
, Bangkok,<country>Thailand</country>
</aff>
<aff id="aff70"><label>70</label>
<institution>Genetic Susceptibility Group, International Agency for Research on Cancer</institution>
, Lyon,<country>France</country>
</aff>
<aff id="aff71"><label>71</label>
<institution>Department of Laboratory Medicine and Pathology, Mayo Clinic</institution>
, Rochester, MN,<country>USA</country>
</aff>
<aff id="aff72"><label>72</label>
<institution>Department of Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, The Ohio State University</institution>
, Columbus, OH,<country>USA</country>
</aff>
<aff id="aff73"><label>73</label>
<institution>Mayo Clinic</institution>
, Rochester, MN,<country>USA</country>
</aff>
<aff id="aff74"><label>74</label>
<institution>Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research "Demokritos"</institution>
, Athens,<country>Greece</country>
</aff>
<aff id="aff75"><label>75</label>
<institution>Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research</institution>
, London,<country>UK</country>
</aff>
<aff id="aff76"><label>76</label>
<institution>London School of Hygiene and Tropical Medicine</institution>
, London,<country>UK</country>
</aff>
<aff id="aff77"><label>77</label>
<institution>Department of Obstetrics and Gynecology, University of Heidelberg</institution>
, Heidelberg,<country>Germany</country>
</aff>
<aff id="aff78"><label>78</label>
<institution>National Center for Tumor Diseases, University of Heidelberg</institution>
, Heidelberg,<country>Germany</country>
</aff>
<aff id="aff79"><label>79</label>
<institution>Molecular Epidemiology Group, German Cancer Research Center (DKFZ)</institution>
, Heidelberg,<country>Germany</country>
</aff>
<aff id="aff80"><label>80</label>
<institution>Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer</institution>
, Villejuif,<country>France</country>
</aff>
<aff id="aff81"><label>81</label>
<institution>University Paris-Sud, UMRS 1018</institution>
, Villejuif,<country>France</country>
</aff>
<aff id="aff82"><label>82</label>
<institution>Inserm (National Institute of Health and Medical Research)</institution>
, U775 Paris,<country>France</country>
</aff>
<aff id="aff83"><label>83</label>
<institution>Centre de Ressources Biologiques EPIGENETEC</institution>
, Paris,<country>France</country>
</aff>
<aff id="aff84"><label>84</label>
<institution>Copenhagen General Population Study, Herlev University Hospital, University of Copenhagen</institution>
, Copenhagen,<country>Denmark</country>
</aff>
<aff id="aff85"><label>85</label>
<institution>Department of Clinical Biochemistry, Herlev University Hospital, University of Copenhagen</institution>
, Copenhagen,<country>Denmark</country>
</aff>
<aff id="aff86"><label>86</label>
<institution>Department of Breast Surgery, Herlev University Hospital, University of Copenhagen</institution>
, Copenhagen,<country>Denmark</country>
</aff>
<aff id="aff87"><label>87</label>
<institution>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ)</institution>
, Heidelberg,<country>Germany</country>
</aff>
<aff id="aff88"><label>88</label>
<institution>German Cancer Consortium (DKTK)</institution>
, Heidelberg,<country>Germany</country>
</aff>
<aff id="aff89"><label>89</label>
<institution>Saarland Cancer Registry</institution>
, Saarbrücken,<country>Germany</country>
</aff>
<aff id="aff90"><label>90</label>
<institution>School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland</institution>
, Kuopio,<country>Finland</country>
</aff>
<aff id="aff91"><label>91</label>
<institution>Biocenter Kuopio, University of Eastern Finland</institution>
, Kuopio,<country>Finland</country>
</aff>
<aff id="aff92"><label>92</label>
<institution>Department of Clinical Pathology, Kuopio University Hospital</institution>
, Kuopio,<country>Finland</country>
</aff>
<aff id="aff93"><label>93</label>
<institution>School of Medicine, Institute of Clinical Medicine, Oncology, University of Eastern Finland</institution>
, Kuopio,<country>Finland</country>
</aff>
<aff id="aff94"><label>94</label>
<institution>Cancer Center, Kuopio University Hospital</institution>
, Kuopio,<country>Finland</country>
</aff>
<aff id="aff95"><label>95</label>
<institution>Vesalius Research Center (VRC), VIB</institution>
, Leuven,<country>Belgium</country>
</aff>
<aff id="aff96"><label>96</label>
<institution>Multidisciplinary Breast Center, University Hospital Gasthuisberg</institution>
, Leuven,<country>Belgium</country>
</aff>
<aff id="aff97"><label>97</label>
<institution>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ)</institution>
, Heidelberg,<country>Germany</country>
</aff>
<aff id="aff98"><label>98</label>
<institution>Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf</institution>
, Hamburg,<country>Germany</country>
</aff>
<aff id="aff99"><label>99</label>
<institution>Department of Cancer Epidemiology/Clinical Cancer Registry, University Clinic Hamburg-Eppendorf</institution>
, Hamburg,<country>Germany</country>
</aff>
<aff id="aff100"><label>100</label>
<institution>Department of Health Sciences Research, Mayo Clinic</institution>
, Rochester, MN,<country>USA</country>
</aff>
<aff id="aff101"><label>101</label>
<institution>Cancer Epidemiology Centre, Cancer Council Victoria</institution>
, Melbourne,<country>Australia</country>
</aff>
<aff id="aff102"><label>102</label>
<institution>University of Hawaii Cancer Center</institution>
, Honolulu, HI,<country>USA</country>
</aff>
<aff id="aff103"><label>103</label>
<institution>Cancer Genomics Laboratory, Centre Hospitalier Universitaire de Quebec Research Center and Laval University</institution>
, Quebec,<country>Canada</country>
</aff>
<aff id="aff104"><label>104</label>
<institution>Department of Medicine, McGill University, Montreal</institution>
, Montreal, Quebec,<country>Canada</country>
</aff>
<aff id="aff105"><label>105</label>
<institution>Division of Clinical Epidemiology, McGill University Health Centre, Royal Victoria Hospital</institution>
, Montreal, Quebec,<country>Canada</country>
</aff>
<aff id="aff106"><label>106</label>
<institution>Département de médecine sociale et préventive, Département de santé environnementale et santé au travail, Université de Montréal</institution>
, Montreal, Quebec,<country>Canada</country>
</aff>
<aff id="aff107"><label>107</label>
<institution>Laboratory of Cancer Genetics and Tumor Biology, Department of Clinical Chemistry and Biocenter Oulu, University of Oulu, Oulu University Hospital</institution>
, Oulu,<country>Finland</country>
</aff>
<aff id="aff108"><label>108</label>
<institution>Department of Oncology, Oulu University Hospital, University of Oulu</institution>
, Oulu,<country>Finland</country>
</aff>
<aff id="aff109"><label>109</label>
<institution>Department of Surgery, Oulu University Hospital, University of Oulu</institution>
, Oulu,<country>Finland</country>
</aff>
<aff id="aff110"><label>110</label>
<institution>Department of Human Genetics, Leiden University Medical Center</institution>
, Leiden,<country>The Netherlands</country>
</aff>
<aff id="aff111"><label>111</label>
<institution>Department of Surgical Oncology, Leiden University Medical Center</institution>
, Leiden,<country>The Netherlands</country>
</aff>
<aff id="aff112"><label>112</label>
<institution>Department of Medical Oncology, Family Cancer Clinic, Erasmus University Medical Centre</institution>
, Rotterdam,<country>The Netherlands</country>
</aff>
<aff id="aff113"><label>113</label>
<institution>Division of Cancer Epidemiology and Genetics, National Cancer Institute</institution>
, Rockville, MD,<country>USA</country>
</aff>
<aff id="aff114"><label>114</label>
<institution>Division of Genetics and Epidemiology, Institute of Cancer Research and Breakthrough Breast Cancer Research Centre</institution>
, London,<country>UK</country>
</aff>
<aff id="aff115"><label>115</label>
<institution>Department of Cancer Epidemiology and Prevention, M. Sklodowska-Curie Memorial Cancer Center & Institute of Oncology</institution>
, Warsaw,<country>Poland</country>
</aff>
<aff id="aff116"><label>116</label>
<institution>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet</institution>
, Stockholm,<country>Sweden</country>
</aff>
<aff id="aff117"><label>117</label>
<institution>Department of Clinical Genetics, Family Cancer Clinic, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</aff>
<aff id="aff118"><label>118</label>
<institution>Department of Surgical Oncology, Family Cancer Clinic, Erasmus University Medical Centre</institution>
, Rotterdam,<country>The Netherlands</country>
</aff>
<aff id="aff119"><label>119</label>
<institution>Human Genetics Division, Genome Institute of Singapore</institution>
, Singapore,<country>Singapore</country>
</aff>
<aff id="aff120"><label>120</label>
<institution>Department of Genetics and Pathology, Pomeranian Medical University</institution>
, Szczecin,<country>Poland</country>
</aff>
<aff id="aff121"><label>121</label>
<institution>Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital</institution>
, Helsinki,<country>Finland</country>
</aff>
<aff id="aff122"><label>122</label>
<institution>Department of Clinical Genetics, Helsinki University Central Hospital</institution>
, Helsinki,<country>Finland</country>
</aff>
<aff id="aff123"><label>123</label>
<institution>Department of Oncology, Helsinki University Central Hospital</institution>
, Helsinki,<country>Finland</country>
</aff>
<aff id="aff124"><label>124</label>
<institution>Department of Obstetrics and Gynaecology, Hannover Medical School</institution>
, Hannover,<country>Germany</country>
</aff>
<aff id="aff125"><label>125</label>
<institution>Department of Radiation Oncology, Hannover Medical School</institution>
, Hannover,<country>Germany</country>
</aff>
<aff id="aff126"><label>126</label>
<institution>Servicio de Cirugía General y Especialidades, Hospital Monte Naranco</institution>
, Oviedo,<country>Spain</country>
</aff>
<aff id="aff127"><label>127</label>
<institution>Servicio de Oncología Médica, Hospital Universitario La Paz</institution>
, Madrid,<country>Spain</country>
</aff>
</contrib-group>
<author-notes><corresp id="caf1"><label>*</label>
E-mail: <email>roger.milne@cancervic.org.au</email>
</corresp>
</author-notes>
<pub-date pub-type="ppub"><day>18</day>
<month>02</month>
<year>2014</year>
</pub-date>
<pub-date pub-type="epub"><day>18</day>
<month>02</month>
<year>2014</year>
</pub-date>
<volume>110</volume>
<issue>4</issue>
<fpage>1088</fpage>
<lpage>1100</lpage>
<history><date date-type="received"><day>04</day>
<month>09</month>
<year>2013</year>
</date>
<date date-type="rev-recd"><day>08</day>
<month>11</month>
<year>2013</year>
</date>
<date date-type="accepted"><day>15</day>
<month>11</month>
<year>2013</year>
</date>
</history>
<permissions><copyright-statement>Copyright © 2014 Cancer Research UK</copyright-statement>
<copyright-year>2014</copyright-year>
<copyright-holder>Cancer Research UK</copyright-holder>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc-sa/3.0/"><license-p>From twelve months after its original publication, this work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/</license-p>
</license>
</permissions>
<abstract><sec><title>Background:</title>
<p>Breast cancer is one of the most common malignancies in women. Genome-wide association studies have identified <italic>FGFR2</italic>
as a breast cancer susceptibility gene. Common variation in other fibroblast growth factor (FGF) receptors might also modify risk. We tested this hypothesis by studying genotyped single-nucleotide polymorphisms (SNPs) and imputed SNPs in <italic>FGFR1, FGFR3, FGFR4</italic>
and <italic>FGFRL1</italic>
in the Breast Cancer Association Consortium.</p>
</sec>
<sec><title>Methods:</title>
<p>Data were combined from 49 studies, including 53 835 cases and 50 156 controls, of which 89 050 (46 450 cases and 42 600 controls) were of European ancestry, 12 893 (6269 cases and 6624 controls) of Asian and 2048 (1116 cases and 932 controls) of African ancestry. Associations with risk of breast cancer, overall and by disease sub-type, were assessed using unconditional logistic regression.</p>
</sec>
<sec><title>Results:</title>
<p>Little evidence of association with breast cancer risk was observed for SNPs in the FGF receptor genes. The strongest evidence in European women was for rs743682 in <italic>FGFR3</italic>
; the estimated per-allele odds ratio was 1.05 (95% confidence interval=1.02–1.09, <italic>P=</italic>
0.0020), which is substantially lower than that observed for SNPs in <italic>FGFR2.</italic>
</p>
</sec>
<sec><title>Conclusion:</title>
<p>Our results suggest that common variants in the other FGF receptors are not associated with risk of breast cancer to the degree observed for <italic>FGFR2</italic>
.</p>
</sec>
</abstract>
<kwd-group><kwd>breast cancer</kwd>
<kwd>SNP</kwd>
<kwd>FGF receptors</kwd>
<kwd>susceptibility</kwd>
<kwd>disease subtypes</kwd>
</kwd-group>
</article-meta>
</front>
<floats-group><table-wrap id="tbl1"><label>Table 1</label>
<caption><title>Number of cases and controls included, by study</title>
</caption>
<table frame="hsides" rules="groups" border="1"><colgroup><col align="left"></col>
<col align="left"></col>
<col align="char" char="."></col>
<col align="char" char="."></col>
<col align="char" char="."></col>
<col align="char" char="."></col>
</colgroup>
<thead valign="bottom"><tr><th align="left" valign="top" charoff="50"><bold>Study</bold>
</th>
<th align="left" valign="top" charoff="50"><bold>Country</bold>
</th>
<th align="center" valign="top" char="." charoff="50"><bold>Controls</bold>
</th>
<th align="center" valign="top" char="." charoff="50"><bold>Cases</bold>
</th>
<th align="center" valign="top" char="." charoff="50"><bold>ER+</bold>
</th>
<th align="center" valign="top" char="." charoff="50"><bold>ER−</bold>
</th>
</tr>
</thead>
<tbody valign="top"><tr><td colspan="6" align="left" valign="top" charoff="50"><bold>White European women</bold>
<hr></hr>
</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Australian Breast Cancer Family Study<xref ref-type="fn" rid="t1-fn2">a</xref>
(ABCFS)</td>
<td align="left" valign="top" charoff="50">Australia</td>
<td align="char" valign="top" char="." charoff="50">551</td>
<td align="char" valign="top" char="." charoff="50">790</td>
<td align="char" valign="top" char="." charoff="50">456</td>
<td align="char" valign="top" char="." charoff="50">261</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Amsterdam Breast Cancer Study (ABCS)</td>
<td align="left" valign="top" charoff="50">Netherlands</td>
<td align="char" valign="top" char="." charoff="50">1429</td>
<td align="char" valign="top" char="." charoff="50">1325</td>
<td align="char" valign="top" char="." charoff="50">420</td>
<td align="char" valign="top" char="." charoff="50">153</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Bavarian Breast Cancer Cases and Controls (BBCC)</td>
<td align="left" valign="top" charoff="50">Germany</td>
<td align="char" valign="top" char="." charoff="50">458</td>
<td align="char" valign="top" char="." charoff="50">564</td>
<td align="char" valign="top" char="." charoff="50">460</td>
<td align="char" valign="top" char="." charoff="50">83</td>
</tr>
<tr><td align="left" valign="top" charoff="50">British Breast Cancer Study (BBCS)</td>
<td align="left" valign="top" charoff="50">UK</td>
<td align="char" valign="top" char="." charoff="50">1397</td>
<td align="char" valign="top" char="." charoff="50">1554</td>
<td align="char" valign="top" char="." charoff="50">507</td>
<td align="char" valign="top" char="." charoff="50">114</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Breast Cancer In Galway Genetic Study (BIGGS)</td>
<td align="left" valign="top" charoff="50">Ireland</td>
<td align="char" valign="top" char="." charoff="50">719</td>
<td align="char" valign="top" char="." charoff="50">836</td>
<td align="char" valign="top" char="." charoff="50">495</td>
<td align="char" valign="top" char="." charoff="50">154</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Breast Cancer Study of the University Clinic Heidelberg (BSUCH)</td>
<td align="left" valign="top" charoff="50">Germany</td>
<td align="char" valign="top" char="." charoff="50">954</td>
<td align="char" valign="top" char="." charoff="50">852</td>
<td align="char" valign="top" char="." charoff="50">499</td>
<td align="char" valign="top" char="." charoff="50">154</td>
</tr>
<tr><td align="left" valign="top" charoff="50">CECILE Breast Cancer Study (CECILE)</td>
<td align="left" valign="top" charoff="50">France</td>
<td align="char" valign="top" char="." charoff="50">999</td>
<td align="char" valign="top" char="." charoff="50">1019</td>
<td align="char" valign="top" char="." charoff="50">797</td>
<td align="char" valign="top" char="." charoff="50">144</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Copenhagen General Population Study (CGPS)</td>
<td align="left" valign="top" charoff="50">Denmark</td>
<td align="char" valign="top" char="." charoff="50">4086</td>
<td align="char" valign="top" char="." charoff="50">2901</td>
<td align="char" valign="top" char="." charoff="50">1919</td>
<td align="char" valign="top" char="." charoff="50">357</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Spanish National Cancer Centre Breast Cancer Study (CNIO-BCS)</td>
<td align="left" valign="top" charoff="50">Spain</td>
<td align="char" valign="top" char="." charoff="50">876</td>
<td align="char" valign="top" char="." charoff="50">902</td>
<td align="char" valign="top" char="." charoff="50">242</td>
<td align="char" valign="top" char="." charoff="50">88</td>
</tr>
<tr><td align="left" valign="top" charoff="50">California Teachers Study (CTS)</td>
<td align="left" valign="top" charoff="50">USA</td>
<td align="char" valign="top" char="." charoff="50">71</td>
<td align="char" valign="top" char="." charoff="50">68</td>
<td align="char" valign="top" char="." charoff="50">0</td>
<td align="char" valign="top" char="." charoff="50">17</td>
</tr>
<tr><td align="left" valign="top" charoff="50">ESTHER Breast Cancer Study (ESTHER)</td>
<td align="left" valign="top" charoff="50">Germany</td>
<td align="char" valign="top" char="." charoff="50">502</td>
<td align="char" valign="top" char="." charoff="50">478</td>
<td align="char" valign="top" char="." charoff="50">304</td>
<td align="char" valign="top" char="." charoff="50">98</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Gene–Environment Interaction and Breast Cancer in Germany (GENICA)</td>
<td align="left" valign="top" charoff="50">Germany</td>
<td align="char" valign="top" char="." charoff="50">427</td>
<td align="char" valign="top" char="." charoff="50">465</td>
<td align="char" valign="top" char="." charoff="50">328</td>
<td align="char" valign="top" char="." charoff="50">119</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Helsinki Breast Cancer Study (HEBCS)</td>
<td align="left" valign="top" charoff="50">Finland</td>
<td align="char" valign="top" char="." charoff="50">1234</td>
<td align="char" valign="top" char="." charoff="50">1664</td>
<td align="char" valign="top" char="." charoff="50">1295</td>
<td align="char" valign="top" char="." charoff="50">237</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Hannover-Minsk Breast Cancer Study (HMBCS)</td>
<td align="left" valign="top" charoff="50">Belarus</td>
<td align="char" valign="top" char="." charoff="50">130</td>
<td align="char" valign="top" char="." charoff="50">690</td>
<td align="char" valign="top" char="." charoff="50">37</td>
<td align="char" valign="top" char="." charoff="50">0</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Karolinska Breast Cancer Study (KARBAC)</td>
<td align="left" valign="top" charoff="50">Sweden</td>
<td align="char" valign="top" char="." charoff="50">662</td>
<td align="char" valign="top" char="." charoff="50">722</td>
<td align="char" valign="top" char="." charoff="50">338</td>
<td align="char" valign="top" char="." charoff="50">63</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Kuopio Breast Cancer Project (KBCP)</td>
<td align="left" valign="top" charoff="50">Finland</td>
<td align="char" valign="top" char="." charoff="50">251</td>
<td align="char" valign="top" char="." charoff="50">445</td>
<td align="char" valign="top" char="." charoff="50">304</td>
<td align="char" valign="top" char="." charoff="50">97</td>
</tr>
<tr><td align="left" valign="top" charoff="50">kConFab/Australian Ovarian Cancer Study (kConFab/AOCS)</td>
<td align="left" valign="top" charoff="50">Australia</td>
<td align="char" valign="top" char="." charoff="50">897</td>
<td align="char" valign="top" char="." charoff="50">613</td>
<td align="char" valign="top" char="." charoff="50">162</td>
<td align="char" valign="top" char="." charoff="50">59</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Leuven Multidisciplinary Breast Centre (LMBC)</td>
<td align="left" valign="top" charoff="50">Belgium</td>
<td align="char" valign="top" char="." charoff="50">1388</td>
<td align="char" valign="top" char="." charoff="50">2671</td>
<td align="char" valign="top" char="." charoff="50">2071</td>
<td align="char" valign="top" char="." charoff="50">379</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Mammary Carcinoma Risk Factor Investigation (MARIE)</td>
<td align="left" valign="top" charoff="50">Germany</td>
<td align="char" valign="top" char="." charoff="50">1778</td>
<td align="char" valign="top" char="." charoff="50">1818</td>
<td align="char" valign="top" char="." charoff="50">1349</td>
<td align="char" valign="top" char="." charoff="50">399</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Milan Breast Cancer Study Group (MBCSG)</td>
<td align="left" valign="top" charoff="50">Italy</td>
<td align="char" valign="top" char="." charoff="50">400</td>
<td align="char" valign="top" char="." charoff="50">488</td>
<td align="char" valign="top" char="." charoff="50">149</td>
<td align="char" valign="top" char="." charoff="50">42</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Mayo Clinic Breast Cancer Study (MCBCS)</td>
<td align="left" valign="top" charoff="50">USA</td>
<td align="char" valign="top" char="." charoff="50">1931</td>
<td align="char" valign="top" char="." charoff="50">1862</td>
<td align="char" valign="top" char="." charoff="50">1486</td>
<td align="char" valign="top" char="." charoff="50">295</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Melbourne Collaborative Cohort Study (MCCS)</td>
<td align="left" valign="top" charoff="50">Australia</td>
<td align="char" valign="top" char="." charoff="50">511</td>
<td align="char" valign="top" char="." charoff="50">614</td>
<td align="char" valign="top" char="." charoff="50">352</td>
<td align="char" valign="top" char="." charoff="50">119</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Multi-ethnic Cohort (MEC)</td>
<td align="left" valign="top" charoff="50">USA</td>
<td align="char" valign="top" char="." charoff="50">741</td>
<td align="char" valign="top" char="." charoff="50">731</td>
<td align="char" valign="top" char="." charoff="50">415</td>
<td align="char" valign="top" char="." charoff="50">87</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Montreal Gene–Environment Breast Cancer Study (MTLGEBCS)</td>
<td align="left" valign="top" charoff="50">Canada</td>
<td align="char" valign="top" char="." charoff="50">436</td>
<td align="char" valign="top" char="." charoff="50">489</td>
<td align="char" valign="top" char="." charoff="50">421</td>
<td align="char" valign="top" char="." charoff="50">64</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Norwegian Breast Cancer Study (NBCS)</td>
<td align="left" valign="top" charoff="50">Norway</td>
<td align="char" valign="top" char="." charoff="50">70</td>
<td align="char" valign="top" char="." charoff="50">22</td>
<td align="char" valign="top" char="." charoff="50">0</td>
<td align="char" valign="top" char="." charoff="50">22</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Oulu Breast Cancer Study (OBCS)</td>
<td align="left" valign="top" charoff="50">Finland</td>
<td align="char" valign="top" char="." charoff="50">414</td>
<td align="char" valign="top" char="." charoff="50">507</td>
<td align="char" valign="top" char="." charoff="50">407</td>
<td align="char" valign="top" char="." charoff="50">100</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Ontario Familial Breast Cancer Registry<xref ref-type="fn" rid="t1-fn3">b</xref>
(OFBCR)</td>
<td align="left" valign="top" charoff="50">Canada</td>
<td align="char" valign="top" char="." charoff="50">511</td>
<td align="char" valign="top" char="." charoff="50">1175</td>
<td align="char" valign="top" char="." charoff="50">630</td>
<td align="char" valign="top" char="." charoff="50">268</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Leiden University Medical Centre Breast Cancer Study (ORIGO)</td>
<td align="left" valign="top" charoff="50">Netherlands</td>
<td align="char" valign="top" char="." charoff="50">327</td>
<td align="char" valign="top" char="." charoff="50">357</td>
<td align="char" valign="top" char="." charoff="50">211</td>
<td align="char" valign="top" char="." charoff="50">70</td>
</tr>
<tr><td align="left" valign="top" charoff="50">NCI Polish Breast Cancer Study (PBCS)</td>
<td align="left" valign="top" charoff="50">Poland</td>
<td align="char" valign="top" char="." charoff="50">424</td>
<td align="char" valign="top" char="." charoff="50">519</td>
<td align="char" valign="top" char="." charoff="50">519</td>
<td align="char" valign="top" char="." charoff="50">0</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Karolinska Mammography Project for Risk Prediction of Breast Cancer (pKARMA)</td>
<td align="left" valign="top" charoff="50">Sweden</td>
<td align="char" valign="top" char="." charoff="50">5537</td>
<td align="char" valign="top" char="." charoff="50">5434</td>
<td align="char" valign="top" char="." charoff="50">3672</td>
<td align="char" valign="top" char="." charoff="50">702</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Rotterdam Breast Cancer Study (RBCS)</td>
<td align="left" valign="top" charoff="50">Netherlands</td>
<td align="char" valign="top" char="." charoff="50">699</td>
<td align="char" valign="top" char="." charoff="50">664</td>
<td align="char" valign="top" char="." charoff="50">368</td>
<td align="char" valign="top" char="." charoff="50">131</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Singapore and Sweden Breast Cancer Study (SASBAC)</td>
<td align="left" valign="top" charoff="50">Sweden</td>
<td align="char" valign="top" char="." charoff="50">1378</td>
<td align="char" valign="top" char="." charoff="50">1163</td>
<td align="char" valign="top" char="." charoff="50">663</td>
<td align="char" valign="top" char="." charoff="50">144</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Sheffield Breast Cancer Study (SBCS)</td>
<td align="left" valign="top" charoff="50">UK</td>
<td align="char" valign="top" char="." charoff="50">848</td>
<td align="char" valign="top" char="." charoff="50">843</td>
<td align="char" valign="top" char="." charoff="50">377</td>
<td align="char" valign="top" char="." charoff="50">105</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Studies of Epidemiology and Risk factors in Cancer Heredity (SEARCH)</td>
<td align="left" valign="top" charoff="50">UK</td>
<td align="char" valign="top" char="." charoff="50">8069</td>
<td align="char" valign="top" char="." charoff="50">9347</td>
<td align="char" valign="top" char="." charoff="50">5160</td>
<td align="char" valign="top" char="." charoff="50">1181</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Städtisches Klinikum Karlsruhe Deutsches Krebsforschungszentrum Study (SKKDKFZS)</td>
<td align="left" valign="top" charoff="50">Germany</td>
<td align="char" valign="top" char="." charoff="50">29</td>
<td align="char" valign="top" char="." charoff="50">136</td>
<td align="char" valign="top" char="." charoff="50">0</td>
<td align="char" valign="top" char="." charoff="50">136</td>
</tr>
<tr><td align="left" valign="top" charoff="50">IHCC-Szczecin Breast Cancer Study (SZBCS)</td>
<td align="left" valign="top" charoff="50">Poland</td>
<td align="char" valign="top" char="." charoff="50">315</td>
<td align="char" valign="top" char="." charoff="50">365</td>
<td align="char" valign="top" char="." charoff="50">165</td>
<td align="char" valign="top" char="." charoff="50">60</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Triple Negative Breast Cancer Consortium Study (TNBCC)</td>
<td align="left" valign="top" charoff="50">Various</td>
<td align="char" valign="top" char="." charoff="50">542</td>
<td align="char" valign="top" char="." charoff="50">881</td>
<td align="char" valign="top" char="." charoff="50">0</td>
<td align="char" valign="top" char="." charoff="50">881</td>
</tr>
<tr><td align="left" valign="top" charoff="50">UK Breakthrough Generations Study (UKBGS)<hr></hr>
</td>
<td align="left" valign="top" charoff="50">UK<hr></hr>
</td>
<td align="char" valign="top" char="." charoff="50">470<hr></hr>
</td>
<td align="char" valign="top" char="." charoff="50">476<hr></hr>
</td>
<td align="char" valign="top" char="." charoff="50">96<hr></hr>
</td>
<td align="char" valign="top" char="." charoff="50">22<hr></hr>
</td>
</tr>
<tr><td colspan="6" align="left" valign="top" charoff="50"><bold>Asian women</bold>
<hr></hr>
</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Asian Cancer Project (ACP)</td>
<td align="left" valign="top" charoff="50">Thailand</td>
<td align="char" valign="top" char="." charoff="50">636</td>
<td align="char" valign="top" char="." charoff="50">423</td>
<td align="char" valign="top" char="." charoff="50">92</td>
<td align="char" valign="top" char="." charoff="50">53</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Hospital-based Epidemiologic Research Program at Aichi Cancer Center (HERPACC)</td>
<td align="left" valign="top" charoff="50">Japan</td>
<td align="char" valign="top" char="." charoff="50">1376</td>
<td align="char" valign="top" char="." charoff="50">694</td>
<td align="char" valign="top" char="." charoff="50">395</td>
<td align="char" valign="top" char="." charoff="50">139</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Los Angeles County Asian-American Breast Cancer Case–Control (LAABC)</td>
<td align="left" valign="top" charoff="50">USA</td>
<td align="char" valign="top" char="." charoff="50">990</td>
<td align="char" valign="top" char="." charoff="50">812</td>
<td align="char" valign="top" char="." charoff="50">528</td>
<td align="char" valign="top" char="." charoff="50">138</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Malaysian Breast Cancer Genetic Study (MYBRCA)</td>
<td align="left" valign="top" charoff="50">Malaysia</td>
<td align="char" valign="top" char="." charoff="50">610</td>
<td align="char" valign="top" char="." charoff="50">770</td>
<td align="char" valign="top" char="." charoff="50">422</td>
<td align="char" valign="top" char="." charoff="50">291</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Shanghai Breast Cancer Genetic Study (SBCGS)</td>
<td align="left" valign="top" charoff="50">China</td>
<td align="char" valign="top" char="." charoff="50">892</td>
<td align="char" valign="top" char="." charoff="50">848</td>
<td align="char" valign="top" char="." charoff="50">510</td>
<td align="char" valign="top" char="." charoff="50">276</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Seoul Breast Cancer Study (SEBCS)</td>
<td align="left" valign="top" charoff="50">South Korea</td>
<td align="char" valign="top" char="." charoff="50">1129</td>
<td align="char" valign="top" char="." charoff="50">1162</td>
<td align="char" valign="top" char="." charoff="50">657</td>
<td align="char" valign="top" char="." charoff="50">375</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Singapore Breast Cancer Cohort (SGBCC)</td>
<td align="left" valign="top" charoff="50">Singapore</td>
<td align="char" valign="top" char="." charoff="50">502</td>
<td align="char" valign="top" char="." charoff="50">533</td>
<td align="char" valign="top" char="." charoff="50">272</td>
<td align="char" valign="top" char="." charoff="50">108</td>
</tr>
<tr><td align="left" valign="top" charoff="50">IARC-Thai Breast Cancer (TBCS)</td>
<td align="left" valign="top" charoff="50">Thailand</td>
<td align="char" valign="top" char="." charoff="50">253</td>
<td align="char" valign="top" char="." charoff="50">138</td>
<td align="char" valign="top" char="." charoff="50">26</td>
<td align="char" valign="top" char="." charoff="50">26</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Taiwanese Breast Cancer Study (TWBCS)<hr></hr>
</td>
<td align="left" valign="top" charoff="50">Taiwan<hr></hr>
</td>
<td align="char" valign="top" char="." charoff="50">236<hr></hr>
</td>
<td align="char" valign="top" char="." charoff="50">889<hr></hr>
</td>
<td align="char" valign="top" char="." charoff="50">460<hr></hr>
</td>
<td align="char" valign="top" char="." charoff="50">204<hr></hr>
</td>
</tr>
<tr><td colspan="6" align="left" valign="top" charoff="50"><bold>African</bold>
<hr></hr>
</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Southern Community Cohort Study (SCCS)</td>
<td align="left" valign="top" charoff="50">USA</td>
<td align="char" valign="top" char="." charoff="50">680</td>
<td align="char" valign="top" char="." charoff="50">679</td>
<td align="char" valign="top" char="." charoff="50">0</td>
<td align="char" valign="top" char="." charoff="50">0</td>
</tr>
<tr><td align="left" valign="top" charoff="50">Nashville Breast Health Study (NBHS)</td>
<td align="left" valign="top" charoff="50">USA</td>
<td align="char" valign="top" char="." charoff="50">252</td>
<td align="char" valign="top" char="." charoff="50">437</td>
<td align="char" valign="top" char="." charoff="50">199</td>
<td align="char" valign="top" char="." charoff="50">222</td>
</tr>
<tr><td align="left" valign="top" charoff="50"> </td>
<td align="left" valign="top" charoff="50"> </td>
<td align="char" valign="top" char="." charoff="50"> </td>
<td align="char" valign="top" char="." charoff="50"> </td>
<td align="char" valign="top" char="." charoff="50"> </td>
<td align="char" valign="top" char="." charoff="50"> </td>
</tr>
<tr><td align="left" valign="top" charoff="50">Total</td>
<td align="left" valign="top" charoff="50"> </td>
<td align="char" valign="top" char="." charoff="50">50156</td>
<td align="char" valign="top" char="." charoff="50">53835</td>
<td align="char" valign="top" char="." charoff="50">30635</td>
<td align="char" valign="top" char="." charoff="50">9120</td>
</tr>
</tbody>
</table>
<table-wrap-foot><fn id="t1-fn1"><p>Abbreviations: ER−=estrogen receptor-negative cases; ER+=estrogen receptor-positive cases.</p>
</fn>
<fn id="t1-fn2"><label>a</label>
<p>Australian site of the Breast Cancer Family Registry.</p>
</fn>
<fn id="t1-fn3"><label>b</label>
<p>Ontario site of the Breast Cancer Family Registry.</p>
</fn>
</table-wrap-foot>
</table-wrap>
<table-wrap id="tbl2"><label>Table 2</label>
<caption><title>Summary results for SNPs in FGF receptor genes for white European women</title>
</caption>
<table frame="hsides" rules="groups" border="1"><colgroup><col align="left"></col>
<col align="center"></col>
<col align="char" char="."></col>
<col align="char" char="("></col>
<col align="char" char="("></col>
<col align="char" char="("></col>
<col align="char" char="."></col>
<col align="char" char="("></col>
<col align="char" char="("></col>
<col align="char" char="."></col>
</colgroup>
<thead valign="bottom"><tr><th align="left" valign="top" charoff="50"> <hr></hr>
</th>
<th align="center" valign="top" charoff="50"> <hr></hr>
</th>
<th align="char" valign="top" char="." charoff="50"> <hr></hr>
</th>
<th colspan="3" align="center" valign="top" char="(" charoff="50"><bold>OR (95%CI)</bold>
<hr></hr>
</th>
<th align="char" valign="top" char="." charoff="50"> <hr></hr>
</th>
<th colspan="2" align="center" valign="top" char="(" charoff="50"><bold>OR (95%CI)</bold>
<hr></hr>
</th>
<th align="char" valign="top" char="." charoff="50"> <hr></hr>
</th>
</tr>
<tr><th align="left" valign="top" charoff="50"><bold>SNP</bold>
</th>
<th align="center" valign="top" charoff="50"><bold>Alleles</bold>
</th>
<th align="char" valign="top" char="." charoff="50"><bold>MAF</bold>
</th>
<th align="center" valign="top" char="(" charoff="50"><bold>Aa</bold>
</th>
<th align="center" valign="top" char="(" charoff="50"><bold>aa</bold>
</th>
<th align="center" valign="top" char="(" charoff="50"><bold>per-a-allele</bold>
</th>
<th align="center" valign="top" char="." charoff="50"><italic><bold>P</bold>
</italic>
</th>
<th align="center" valign="top" char="(" charoff="50"><bold>ER−</bold>
</th>
<th align="center" valign="top" char="(" charoff="50"><bold>ER+</bold>
</th>
<th align="center" valign="top" char="." charoff="50"><italic><bold>P-het</bold>
</italic>
</th>
</tr>
</thead>
<tbody valign="top"><tr><td colspan="10" align="left" valign="top" charoff="50"><bold><italic>FGFR1</italic>
</bold>
<hr></hr>
</td>
</tr>
<tr><td align="left" valign="top" charoff="50">rs10958704</td>
<td align="center" valign="top" charoff="50">A<bold>G</bold>
</td>
<td align="char" valign="top" char="." charoff="50">0.40</td>
<td align="char" valign="top" char="(" charoff="50">0.98 (0.95–1.01)</td>
<td align="char" valign="top" char="(" charoff="50">0.98 (0.94–1.02)</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.97–1.01)</td>
<td align="char" valign="top" char="." charoff="50">0.18</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.96–1.03)</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.97–1.02)</td>
<td align="char" valign="top" char="." charoff="50">0.91</td>
</tr>
<tr><td align="left" valign="top" charoff="50">rs17182141</td>
<td align="center" valign="top" charoff="50">A<bold>G</bold>
</td>
<td align="char" valign="top" char="." charoff="50">0.06</td>
<td align="char" valign="top" char="(" charoff="50">1.05 (1.00–1.09)</td>
<td align="char" valign="top" char="(" charoff="50">0.95 (0.75–1.22)</td>
<td align="char" valign="top" char="(" charoff="50">1.04 (1.00–1.08)</td>
<td align="char" valign="top" char="." charoff="50">0.057</td>
<td align="char" valign="top" char="(" charoff="50">1.08 (1.00–1.17)</td>
<td align="char" valign="top" char="(" charoff="50">1.04 (0.99–1.09)</td>
<td align="char" valign="top" char="." charoff="50">0.30</td>
</tr>
<tr><td align="left" valign="top" charoff="50">rs2288696</td>
<td align="center" valign="top" charoff="50">G<bold>A</bold>
</td>
<td align="char" valign="top" char="." charoff="50">0.21</td>
<td align="char" valign="top" char="(" charoff="50">1.02 (0.99–1.05)</td>
<td align="char" valign="top" char="(" charoff="50">1.07 (1.00–1.14)</td>
<td align="char" valign="top" char="(" charoff="50">1.03 (1.00–1.05)</td>
<td align="char" valign="top" char="." charoff="50">0.023</td>
<td align="char" valign="top" char="(" charoff="50">1.05 (1.01–1.10)</td>
<td align="char" valign="top" char="(" charoff="50">1.03 (1.00–1.06)</td>
<td align="char" valign="top" char="." charoff="50">0.35</td>
</tr>
<tr><td align="left" valign="top" charoff="50">rs2411256</td>
<td align="center" valign="top" charoff="50">G<bold>A</bold>
</td>
<td align="char" valign="top" char="." charoff="50">0.24</td>
<td align="char" valign="top" char="(" charoff="50">1.02 (0.99–1.05)</td>
<td align="char" valign="top" char="(" charoff="50">1.01 (0.95–1.07)</td>
<td align="char" valign="top" char="(" charoff="50">1.01 (0.99–1.03)</td>
<td align="char" valign="top" char="." charoff="50">0.36</td>
<td align="char" valign="top" char="(" charoff="50">1.00 (0.95–1.04)</td>
<td align="char" valign="top" char="(" charoff="50">1.01 (0.99–1.04)</td>
<td align="char" valign="top" char="." charoff="50">0.44</td>
</tr>
<tr><td align="left" valign="top" charoff="50">rs2978076</td>
<td align="center" valign="top" charoff="50">G<bold>A</bold>
</td>
<td align="char" valign="top" char="." charoff="50">0.08</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.96–1.03)</td>
<td align="char" valign="top" char="(" charoff="50">1.22 (1.04–1.44)</td>
<td align="char" valign="top" char="(" charoff="50">1.01 (0.98–1.05)</td>
<td align="char" valign="top" char="." charoff="50">0.53</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.92–1.06)</td>
<td align="char" valign="top" char="(" charoff="50">1.02 (0.98–1.06)</td>
<td align="char" valign="top" char="." charoff="50">0.37</td>
</tr>
<tr><td align="left" valign="top" charoff="50">rs2978083</td>
<td align="center" valign="top" charoff="50">G<bold>A</bold>
</td>
<td align="char" valign="top" char="." charoff="50">0.05</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.96–1.03)</td>
<td align="char" valign="top" char="(" charoff="50">1.22 (1.04–1.44)</td>
<td align="char" valign="top" char="(" charoff="50">1.01 (0.98–1.05)</td>
<td align="char" valign="top" char="." charoff="50">0.53</td>
<td align="char" valign="top" char="(" charoff="50">0.97 (0.89–1.06)</td>
<td align="char" valign="top" char="(" charoff="50">1.03 (0.97–1.08)</td>
<td align="char" valign="top" char="." charoff="50">0.27</td>
</tr>
<tr><td align="left" valign="top" charoff="50">rs3758102</td>
<td align="center" valign="top" charoff="50">G<bold>A</bold>
</td>
<td align="char" valign="top" char="." charoff="50">0.26</td>
<td align="char" valign="top" char="(" charoff="50">1.01 (0.98–1.04)</td>
<td align="char" valign="top" char="(" charoff="50">1.02 (0.96–1.07)</td>
<td align="char" valign="top" char="(" charoff="50">1.01 (0.99–1.03)</td>
<td align="char" valign="top" char="." charoff="50">0.35</td>
<td align="char" valign="top" char="(" charoff="50">1.01 (0.97–1.05)</td>
<td align="char" valign="top" char="(" charoff="50">1.01 (0.98–1.04)</td>
<td align="char" valign="top" char="." charoff="50">0.95</td>
</tr>
<tr><td align="left" valign="top" charoff="50">rs3925</td>
<td align="center" valign="top" charoff="50">G<bold>A</bold>
</td>
<td align="char" valign="top" char="." charoff="50">0.23</td>
<td align="char" valign="top" char="(" charoff="50">1.01 (0.98–1.04)</td>
<td align="char" valign="top" char="(" charoff="50">1.00 (0.95–1.07)</td>
<td align="char" valign="top" char="(" charoff="50">1.01 (0.99–1.03)</td>
<td align="char" valign="top" char="." charoff="50">0.51</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.95–1.04)</td>
<td align="char" valign="top" char="(" charoff="50">1.01 (0.99–1.04)</td>
<td align="char" valign="top" char="." charoff="50">0.39</td>
</tr>
<tr><td align="left" valign="top" charoff="50">rs4733930</td>
<td align="center" valign="top" charoff="50">G<bold>A</bold>
</td>
<td align="char" valign="top" char="." charoff="50">0.42</td>
<td align="char" valign="top" char="(" charoff="50">1.00 (0.97–1.03)</td>
<td align="char" valign="top" char="(" charoff="50">1.04 (1.00–1.08)</td>
<td align="char" valign="top" char="(" charoff="50">1.02 (1.00–1.04)</td>
<td align="char" valign="top" char="." charoff="50">0.11</td>
<td align="char" valign="top" char="(" charoff="50">1.03 (0.99–1.07)</td>
<td align="char" valign="top" char="(" charoff="50">1.02 (1.00–1.04)</td>
<td align="char" valign="top" char="." charoff="50">0.67</td>
</tr>
<tr><td align="left" valign="top" charoff="50">rs4733946</td>
<td align="center" valign="top" charoff="50">C<bold>A</bold>
</td>
<td align="char" valign="top" char="." charoff="50">0.08</td>
<td align="char" valign="top" char="(" charoff="50">1.00 (0.97–1.03)</td>
<td align="char" valign="top" char="(" charoff="50">1.04 (1.00–1.08)</td>
<td align="char" valign="top" char="(" charoff="50">1.02 (1.00–1.04)</td>
<td align="char" valign="top" char="." charoff="50">0.11</td>
<td align="char" valign="top" char="(" charoff="50">1.01 (0.95–1.08)</td>
<td align="char" valign="top" char="(" charoff="50">1.04 (1.00–1.09)</td>
<td align="char" valign="top" char="." charoff="50">0.39</td>
</tr>
<tr><td align="left" valign="top" charoff="50">rs6474354</td>
<td align="center" valign="top" charoff="50">G<bold>A</bold>
</td>
<td align="char" valign="top" char="." charoff="50">0.21</td>
<td align="char" valign="top" char="(" charoff="50">0.98 (0.95–1.01)</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.92–1.05)</td>
<td align="char" valign="top" char="(" charoff="50">0.98 (0.96–1.01)</td>
<td align="char" valign="top" char="." charoff="50">0.18</td>
<td align="char" valign="top" char="(" charoff="50">0.96 (0.92–1.01)</td>
<td align="char" valign="top" char="(" charoff="50">0.98 (0.96–1.01)</td>
<td align="char" valign="top" char="." charoff="50">0.37</td>
</tr>
<tr><td align="left" valign="top" charoff="50">rs6996321</td>
<td align="center" valign="top" charoff="50">G<bold>A</bold>
</td>
<td align="char" valign="top" char="." charoff="50">0.39</td>
<td align="char" valign="top" char="(" charoff="50">1.01 (0.98–1.04)</td>
<td align="char" valign="top" char="(" charoff="50">1.00 (0.96–1.04)</td>
<td align="char" valign="top" char="(" charoff="50">1.00 (0.98–1.02)</td>
<td align="char" valign="top" char="." charoff="50">0.95</td>
<td align="char" valign="top" char="(" charoff="50">1.00 (0.97–1.04)</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.97–1.02)</td>
<td align="char" valign="top" char="." charoff="50">0.54</td>
</tr>
<tr><td align="left" valign="top" charoff="50">rs6983315</td>
<td align="center" valign="top" charoff="50">G<bold>A</bold>
</td>
<td align="char" valign="top" char="." charoff="50">0.44</td>
<td align="char" valign="top" char="(" charoff="50">1.01 (0.97–1.04)</td>
<td align="char" valign="top" char="(" charoff="50">0.98 (0.94–1.02)</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.97–1.01)</td>
<td align="char" valign="top" char="." charoff="50">0.39</td>
<td align="char" valign="top" char="(" charoff="50">0.97 (0.93–1.00)</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.97–1.02)</td>
<td align="char" valign="top" char="." charoff="50">0.13</td>
</tr>
<tr><td align="left" valign="top" charoff="50">rs7012413<hr></hr>
</td>
<td align="center" valign="top" charoff="50">G<bold>A</bold>
<hr></hr>
</td>
<td align="char" valign="top" char="." charoff="50">0.30<hr></hr>
</td>
<td align="char" valign="top" char="(" charoff="50">1.00 (0.97–1.02)<hr></hr>
</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.95–1.04)<hr></hr>
</td>
<td align="char" valign="top" char="(" charoff="50">1.00 (0.98–1.02)<hr></hr>
</td>
<td align="char" valign="top" char="." charoff="50">0.69<hr></hr>
</td>
<td align="char" valign="top" char="(" charoff="50">1.00 (0.97–1.04)<hr></hr>
</td>
<td align="char" valign="top" char="(" charoff="50">1.00 (0.98–1.02)<hr></hr>
</td>
<td align="char" valign="top" char="." charoff="50">0.82<hr></hr>
</td>
</tr>
<tr><td colspan="10" align="left" valign="top" charoff="50"><bold><italic>FGFR3</italic>
</bold>
<hr></hr>
</td>
</tr>
<tr><td align="left" valign="top" charoff="50">rs12502543</td>
<td align="center" valign="top" charoff="50">G<bold>A</bold>
</td>
<td align="char" valign="top" char="." charoff="50">0.10</td>
<td align="char" valign="top" char="(" charoff="50">1.04 (1.01–1.08)</td>
<td align="char" valign="top" char="(" charoff="50">1.10 (0.96–1.25)</td>
<td align="char" valign="top" char="(" charoff="50">1.04 (1.01–1.08)</td>
<td align="char" valign="top" char="." charoff="50">0.0076</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.93–1.05)</td>
<td align="char" valign="top" char="(" charoff="50">1.06 (1.02–1.10)</td>
<td align="char" valign="top" char="." charoff="50">0.036</td>
</tr>
<tr><td align="left" valign="top" charoff="50">rs2234909</td>
<td align="center" valign="top" charoff="50">A<bold>G</bold>
</td>
<td align="char" valign="top" char="." charoff="50">0.14</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.95–1.02)</td>
<td align="char" valign="top" char="(" charoff="50">0.97 (0.88–1.07)</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.96–1.01)</td>
<td align="char" valign="top" char="." charoff="50">0.29</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.94–1.04)</td>
<td align="char" valign="top" char="(" charoff="50">0.98 (0.95–1.02)</td>
<td align="char" valign="top" char="." charoff="50">0.77</td>
</tr>
<tr><td align="left" valign="top" charoff="50">rs3135848</td>
<td align="center" valign="top" charoff="50">A<bold>G</bold>
</td>
<td align="char" valign="top" char="." charoff="50">0.28</td>
<td align="char" valign="top" char="(" charoff="50">1.02 (0.99–1.04)</td>
<td align="char" valign="top" char="(" charoff="50">1.02 (0.96–1.07)</td>
<td align="char" valign="top" char="(" charoff="50">1.01 (0.99–1.03)</td>
<td align="char" valign="top" char="." charoff="50">0.31</td>
<td align="char" valign="top" char="(" charoff="50">1.00 (0.96–1.04)</td>
<td align="char" valign="top" char="(" charoff="50">1.01 (0.99–1.04)</td>
<td align="char" valign="top" char="." charoff="50">0.55</td>
</tr>
<tr><td align="left" valign="top" charoff="50">rs743682</td>
<td align="center" valign="top" charoff="50">G<bold>A</bold>
</td>
<td align="char" valign="top" char="." charoff="50">0.09</td>
<td align="char" valign="top" char="(" charoff="50">1.05 (1.01–1.09)</td>
<td align="char" valign="top" char="(" charoff="50">1.16 (1.00–1.34)</td>
<td align="char" valign="top" char="(" charoff="50">1.05 (1.02–1.09)</td>
<td align="char" valign="top" char="." charoff="50">0.0020</td>
<td align="char" valign="top" char="(" charoff="50">1.01 (0.95–1.08)</td>
<td align="char" valign="top" char="(" charoff="50">1.06 (1.02–1.10)</td>
<td align="char" valign="top" char="." charoff="50">0.24</td>
</tr>
<tr><td align="left" valign="top" charoff="50">rs746779<hr></hr>
</td>
<td align="center" valign="top" charoff="50">G<bold>A</bold>
<hr></hr>
</td>
<td align="char" valign="top" char="." charoff="50">0.18<hr></hr>
</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.96–1.02)<hr></hr>
</td>
<td align="char" valign="top" char="(" charoff="50">0.98 (0.90–1.06)<hr></hr>
</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.96–1.01)<hr></hr>
</td>
<td align="char" valign="top" char="." charoff="50">0.29<hr></hr>
</td>
<td align="char" valign="top" char="(" charoff="50">1.00 (0.95–1.05)<hr></hr>
</td>
<td align="char" valign="top" char="(" charoff="50">0.98 (0.95–1.01)<hr></hr>
</td>
<td align="char" valign="top" char="." charoff="50">0.48<hr></hr>
</td>
</tr>
<tr><td colspan="10" align="left" valign="top" charoff="50"><bold><italic>FGFR4</italic>
</bold>
<hr></hr>
</td>
</tr>
<tr><td align="left" valign="top" charoff="50">rs1076891</td>
<td align="center" valign="top" charoff="50">G<bold>A</bold>
</td>
<td align="char" valign="top" char="." charoff="50">0.06</td>
<td align="char" valign="top" char="(" charoff="50">1.03 (0.99–1.08)</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.81–1.22)</td>
<td align="char" valign="top" char="(" charoff="50">1.03 (0.99–1.07)</td>
<td align="char" valign="top" char="." charoff="50">0.14</td>
<td align="char" valign="top" char="(" charoff="50">1.06 (0.98–1.14)</td>
<td align="char" valign="top" char="(" charoff="50">1.01 (0.97–1.06)</td>
<td align="char" valign="top" char="." charoff="50">0.25</td>
</tr>
<tr><td align="left" valign="top" charoff="50">rs1966265</td>
<td align="center" valign="top" charoff="50">G<bold>A</bold>
</td>
<td align="char" valign="top" char="." charoff="50">0.23</td>
<td align="char" valign="top" char="(" charoff="50">0.97 (0.94–1.00)</td>
<td align="char" valign="top" char="(" charoff="50">0.93 (0.88–0.99)</td>
<td align="char" valign="top" char="(" charoff="50">0.97 (0.95–0.99)</td>
<td align="char" valign="top" char="." charoff="50">0.0060</td>
<td align="char" valign="top" char="(" charoff="50">0.98 (0.94–1.03)</td>
<td align="char" valign="top" char="(" charoff="50">0.97 (0.95–1.00)</td>
<td align="char" valign="top" char="." charoff="50">0.54</td>
</tr>
<tr><td align="left" valign="top" charoff="50">rs2456173</td>
<td align="center" valign="top" charoff="50">G<bold>A</bold>
</td>
<td align="char" valign="top" char="." charoff="50">0.21</td>
<td align="char" valign="top" char="(" charoff="50">1.00 (0.97–1.03)</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.92–1.05)</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.97–1.02)</td>
<td align="char" valign="top" char="." charoff="50">0.66</td>
<td align="char" valign="top" char="(" charoff="50">0.98 (0.94–1.02)</td>
<td align="char" valign="top" char="(" charoff="50">1.00 (0.98–1.03)</td>
<td align="char" valign="top" char="." charoff="50">0.34</td>
</tr>
<tr><td align="left" valign="top" charoff="50">rs376618</td>
<td align="center" valign="top" charoff="50">A<bold>G</bold>
</td>
<td align="char" valign="top" char="." charoff="50">0.24</td>
<td align="char" valign="top" char="(" charoff="50">1.00 (0.97–1.03)</td>
<td align="char" valign="top" char="(" charoff="50">0.96 (0.91–1.02)</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.97–1.01)</td>
<td align="char" valign="top" char="." charoff="50">0.33</td>
<td align="char" valign="top" char="(" charoff="50">0.97 (0.93–1.01)</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.97–1.02)</td>
<td align="char" valign="top" char="." charoff="50">0.29</td>
</tr>
<tr><td align="left" valign="top" charoff="50">rs641101</td>
<td align="center" valign="top" charoff="50">G<bold>A</bold>
</td>
<td align="char" valign="top" char="." charoff="50">0.31</td>
<td align="char" valign="top" char="(" charoff="50">1.01 (0.98–1.04)</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.94–1.03)</td>
<td align="char" valign="top" char="(" charoff="50">1.00 (0.98–1.02)</td>
<td align="char" valign="top" char="." charoff="50">0.98</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.95–1.03)</td>
<td align="char" valign="top" char="(" charoff="50">1.00 (0.98–1.02)</td>
<td align="char" valign="top" char="." charoff="50">0.56</td>
</tr>
<tr><td align="left" valign="top" charoff="50">rs6556301<hr></hr>
</td>
<td align="center" valign="top" charoff="50">C<bold>A</bold>
<hr></hr>
</td>
<td align="char" valign="top" char="." charoff="50">0.36<hr></hr>
</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.97–1.02)<hr></hr>
</td>
<td align="char" valign="top" char="(" charoff="50">0.96 (0.92–1.00)<hr></hr>
</td>
<td align="char" valign="top" char="(" charoff="50">0.98 (0.97–1.00)<hr></hr>
</td>
<td align="char" valign="top" char="." charoff="50">0.13<hr></hr>
</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.95–1.02)<hr></hr>
</td>
<td align="char" valign="top" char="(" charoff="50">0.98 (0.96–1.01)<hr></hr>
</td>
<td align="char" valign="top" char="." charoff="50">0.84<hr></hr>
</td>
</tr>
<tr><td colspan="10" align="left" valign="top" charoff="50"><bold><italic>FGFRL1</italic>
</bold>
<hr></hr>
</td>
</tr>
<tr><td align="left" valign="top" charoff="50">rs34869253</td>
<td align="center" valign="top" charoff="50">A<bold>G</bold>
</td>
<td align="char" valign="top" char="." charoff="50">0.43</td>
<td align="char" valign="top" char="(" charoff="50">1.00 (0.97–1.04)</td>
<td align="char" valign="top" char="(" charoff="50">1.00 (0.96–1.04)</td>
<td align="char" valign="top" char="(" charoff="50">1.00 (0.98–1.02)</td>
<td align="char" valign="top" char="." charoff="50">0.96</td>
<td align="char" valign="top" char="(" charoff="50">0.98 (0.94–1.01)</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.97–1.01)</td>
<td align="char" valign="top" char="." charoff="50">0.52</td>
</tr>
<tr><td align="left" valign="top" charoff="50">rs3755955</td>
<td align="center" valign="top" charoff="50">G<bold>A</bold>
</td>
<td align="char" valign="top" char="." charoff="50">0.16</td>
<td align="char" valign="top" char="(" charoff="50">1.00 (0.97–1.03)</td>
<td align="char" valign="top" char="(" charoff="50">1.02 (0.94–1.11)</td>
<td align="char" valign="top" char="(" charoff="50">1.00 (0.98–1.03)</td>
<td align="char" valign="top" char="." charoff="50">0.82</td>
<td align="char" valign="top" char="(" charoff="50">1.00 (0.95–1.05)</td>
<td align="char" valign="top" char="(" charoff="50">1.00 (0.97–1.03)</td>
<td align="char" valign="top" char="." charoff="50">0.83</td>
</tr>
<tr><td align="left" valign="top" charoff="50">rs4505759</td>
<td align="center" valign="top" charoff="50">G<bold>A</bold>
</td>
<td align="char" valign="top" char="." charoff="50">0.30</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.96–1.02)</td>
<td align="char" valign="top" char="(" charoff="50">0.98 (0.93–1.03)</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.97–1.00)</td>
<td align="char" valign="top" char="." charoff="50">0.38</td>
<td align="char" valign="top" char="(" charoff="50">1.00 (0.96–1.04)</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.97–1.02)</td>
<td align="char" valign="top" char="." charoff="50">0.78</td>
</tr>
<tr><td align="left" valign="top" charoff="50">rs4647932</td>
<td align="center" valign="top" charoff="50">G<bold>A</bold>
</td>
<td align="char" valign="top" char="." charoff="50">0.06</td>
<td align="char" valign="top" char="(" charoff="50">1.04 (0.99–1.08)</td>
<td align="char" valign="top" char="(" charoff="50">0.98 (0.80–1.20)</td>
<td align="char" valign="top" char="(" charoff="50">1.03 (0.99–1.07)</td>
<td align="char" valign="top" char="." charoff="50">0.14</td>
<td align="char" valign="top" char="(" charoff="50">1.06 (0.98–1.14)</td>
<td align="char" valign="top" char="(" charoff="50">1.02 (0.97–1.06)</td>
<td align="char" valign="top" char="." charoff="50">0.31</td>
</tr>
<tr><td align="left" valign="top" charoff="50">rs6855233</td>
<td align="center" valign="top" charoff="50">A<bold>G</bold>
</td>
<td align="char" valign="top" char="." charoff="50">0.29</td>
<td align="char" valign="top" char="(" charoff="50">0.99 (0.97–1.02)</td>
<td align="char" valign="top" char="(" charoff="50">1.03 (0.98–1.08)</td>
<td align="char" valign="top" char="(" charoff="50">1.01 (0.98–1.03)</td>
<td align="char" valign="top" char="." charoff="50">0.62</td>
<td align="char" valign="top" char="(" charoff="50">0.98 (0.94–1.02)</td>
<td align="char" valign="top" char="(" charoff="50">1.00 (0.98–1.03)</td>
<td align="char" valign="top" char="." charoff="50">0.31</td>
</tr>
<tr><td align="left" valign="top" charoff="50">rs748651</td>
<td align="center" valign="top" charoff="50">A<bold>G</bold>
</td>
<td align="char" valign="top" char="." charoff="50">0.48</td>
<td align="char" valign="top" char="(" charoff="50">1.00 (0.97–1.03)</td>
<td align="char" valign="top" char="(" charoff="50">1.02 (0.98–1.06)</td>
<td align="char" valign="top" char="(" charoff="50">1.01 (0.99–1.03)</td>
<td align="char" valign="top" char="." charoff="50">0.31</td>
<td align="char" valign="top" char="(" charoff="50">1.03 (0.99–1.07)</td>
<td align="char" valign="top" char="(" charoff="50">1.01 (0.98–1.03)</td>
<td align="char" valign="top" char="." charoff="50">0.22</td>
</tr>
</tbody>
</table>
<table-wrap-foot><fn id="t2-fn1"><p>Abbreviations: SNP=single-nucleotide polymorphism; FGF=fibroblast growth factor; OR=odds ratio where A is the common allele, a is the rare allele and both Aa and aa are compared with AA genotypes; CI=confidence interval; MAF=minor allele frequency; <italic>P</italic>
=<italic>P</italic>
-value for the per-a-allele model; ER−=results (per a-allele) for risk of estrogen receptor-negative disease; ER+=results (per a-allele) for risk of estrogen receptor-positive disease; <italic>P-het</italic>
=<italic>P</italic>
-value for heterogeneity by disease sub-type defined by estrogen receptor status.</p>
</fn>
</table-wrap-foot>
</table-wrap>
</floats-group>
</pmc>
</record>
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