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<TEI>
<teiHeader>
<fileDesc>
<titleStmt>
<title xml:lang="en">Review of screening for pancreatic cancer in high risk individuals</title>
<author>
<name sortKey="Stoita, Alina" sort="Stoita, Alina" uniqKey="Stoita A" first="Alina" last="Stoita">Alina Stoita</name>
</author>
<author>
<name sortKey="Penman, Ian D" sort="Penman, Ian D" uniqKey="Penman I" first="Ian D" last="Penman">Ian D. Penman</name>
</author>
<author>
<name sortKey="Williams, David B" sort="Williams, David B" uniqKey="Williams D" first="David B" last="Williams">David B. Williams</name>
</author>
</titleStmt>
<publicationStmt>
<idno type="wicri:source">PMC</idno>
<idno type="pmid">21633635</idno>
<idno type="pmc">3103788</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103788</idno>
<idno type="RBID">PMC:3103788</idno>
<idno type="doi">10.3748/wjg.v17.i19.2365</idno>
<date when="2011">2011</date>
<idno type="wicri:Area/Pmc/Corpus">002F06</idno>
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<title xml:lang="en" level="a" type="main">Review of screening for pancreatic cancer in high risk individuals</title>
<author>
<name sortKey="Stoita, Alina" sort="Stoita, Alina" uniqKey="Stoita A" first="Alina" last="Stoita">Alina Stoita</name>
</author>
<author>
<name sortKey="Penman, Ian D" sort="Penman, Ian D" uniqKey="Penman I" first="Ian D" last="Penman">Ian D. Penman</name>
</author>
<author>
<name sortKey="Williams, David B" sort="Williams, David B" uniqKey="Williams D" first="David B" last="Williams">David B. Williams</name>
</author>
</analytic>
<series>
<title level="j">World Journal of Gastroenterology : WJG</title>
<idno type="ISSN">1007-9327</idno>
<imprint>
<date when="2011">2011</date>
</imprint>
</series>
</biblStruct>
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<textClass></textClass>
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<front>
<div type="abstract" xml:lang="en">
<p>Pancreatic cancer is difficult to diagnose at an early stage and is associated with a very poor survival. Ten percent of pancreatic cancers result from genetic susceptibility and/or familial aggregation. Individuals from families with multiple affected first-degree relatives and those with a known cancer-causing genetic mutation have been shown to be at much higher risk of developing pancreatic cancer. Recent efforts have focused on detecting disease at an earlier stage to improve survival in these high-risk groups. This article reviews high-risk groups, screening methods, and current screening programs and their results.</p>
</div>
</front>
</TEI>
<pmc article-type="review-article">
<pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">World J Gastroenterol</journal-id>
<journal-id journal-id-type="publisher-id">WJG</journal-id>
<journal-title-group>
<journal-title>World Journal of Gastroenterology : WJG</journal-title>
</journal-title-group>
<issn pub-type="ppub">1007-9327</issn>
<publisher>
<publisher-name>Baishideng Publishing Group Co., Limited</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">21633635</article-id>
<article-id pub-id-type="pmc">3103788</article-id>
<article-id pub-id-type="other">jWJG.v17.i19.pg2365</article-id>
<article-id pub-id-type="doi">10.3748/wjg.v17.i19.2365</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Topic Highlight</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Review of screening for pancreatic cancer in high risk individuals</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Stoita</surname>
<given-names>Alina</given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Penman</surname>
<given-names>Ian D</given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Williams</surname>
<given-names>David B</given-names>
</name>
</contrib>
<aff>Alina Stoita, David B Williams, Department of Gastroenterology, St Vincent’s Hospital, 390 Victoria Street, Darlinghurst, 2010, NSW, Australia</aff>
<aff>Ian D Penman, Centre for Liver and Digestive Disorders, Royal Infirmary of Edinburgh, 51 Little France Crescent, Edinburgh, EH16 4SA, United Kingdom</aff>
</contrib-group>
<author-notes>
<fn>
<p>Author contributions: All authors made an equal contribution.</p>
<p>Correspondence to: Dr. Alina Stoita, Department of Gastroenterology, St Vincent’s Hospital, 390 Victoria Street, Darlinghurt, 2010, NSW, Australia.
<email>alinastoita@yahoo.com.au</email>
</p>
<p>Telephone: +61-2-8382-2061 Fax: +61-2-83823983</p>
</fn>
</author-notes>
<pub-date pub-type="ppub">
<day>21</day>
<month>5</month>
<year>2011</year>
</pub-date>
<pub-date pub-type="epub">
<day>21</day>
<month>5</month>
<year>2011</year>
</pub-date>
<volume>17</volume>
<issue>19</issue>
<fpage>2365</fpage>
<lpage>2371</lpage>
<history>
<date date-type="received">
<day>17</day>
<month>9</month>
<year>2010</year>
</date>
<date date-type="rev-recd">
<day>17</day>
<month>12</month>
<year>2010</year>
</date>
<date date-type="accepted">
<day>24</day>
<month>12</month>
<year>2010</year>
</date>
</history>
<permissions>
<copyright-statement>©2011 Baishideng Publishing Group Co., Limited. All rights reserved.</copyright-statement>
<copyright-year>2011</copyright-year>
</permissions>
<abstract>
<p>Pancreatic cancer is difficult to diagnose at an early stage and is associated with a very poor survival. Ten percent of pancreatic cancers result from genetic susceptibility and/or familial aggregation. Individuals from families with multiple affected first-degree relatives and those with a known cancer-causing genetic mutation have been shown to be at much higher risk of developing pancreatic cancer. Recent efforts have focused on detecting disease at an earlier stage to improve survival in these high-risk groups. This article reviews high-risk groups, screening methods, and current screening programs and their results.</p>
</abstract>
<kwd-group>
<kwd>Pancreatic cancer</kwd>
<kwd>Familial cancer</kwd>
<kwd>Cancer screening</kwd>
<kwd>Risk factors</kwd>
<kwd>Endoscopic ultrasound</kwd>
<kwd>Hereditary cancer</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>

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