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<title xml:lang="en">Highlights of the 11th International
<named-content content-type="genus-species">Bordetella</named-content>
Symposium: from Basic Biology to Vaccine Development</title>
<author>
<name sortKey="Carbonetti, Nicholas H" sort="Carbonetti, Nicholas H" uniqKey="Carbonetti N" first="Nicholas H." last="Carbonetti">Nicholas H. Carbonetti</name>
<affiliation>
<nlm:aff id="aff1">University of Maryland School of Medicine, Baltimore, Maryland, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Wirsing Von Konig, Carl Heinz" sort="Wirsing Von Konig, Carl Heinz" uniqKey="Wirsing Von Konig C" first="Carl Heinz" last="Wirsing Von König">Carl Heinz Wirsing Von König</name>
<affiliation>
<nlm:aff id="aff2">Labor:Medizin Krefeld MVZ GmbH, Krefeld, Germany</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Lan, Ruiting" sort="Lan, Ruiting" uniqKey="Lan R" first="Ruiting" last="Lan">Ruiting Lan</name>
<affiliation>
<nlm:aff id="aff3">School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Jacob Dubuisson, Francoise" sort="Jacob Dubuisson, Francoise" uniqKey="Jacob Dubuisson F" first="Francoise" last="Jacob-Dubuisson">Francoise Jacob-Dubuisson</name>
<affiliation>
<nlm:aff id="aff4">Institut Pasteur de Lille, Inserm U1019, CNRS UMR8204, University of Lille, Center for Infection and Immunity of Lille, Lille, France</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Cotter, Peggy A" sort="Cotter, Peggy A" uniqKey="Cotter P" first="Peggy A." last="Cotter">Peggy A. Cotter</name>
<affiliation>
<nlm:aff id="aff5">University of North Carolina—Chapel Hill School of Medicine, Chapel Hill, North Carolina, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Deora, Rajendar" sort="Deora, Rajendar" uniqKey="Deora R" first="Rajendar" last="Deora">Rajendar Deora</name>
<affiliation>
<nlm:aff id="aff6">Wake Forest School of Medicine, Winston-Salem, North Carolina, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Merkel, Tod J" sort="Merkel, Tod J" uniqKey="Merkel T" first="Tod J." last="Merkel">Tod J. Merkel</name>
<affiliation>
<nlm:aff id="aff7">Center for Biologics Evaluation and Research, FDA, Silver Spring, Maryland, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Van Els, Cecile A" sort="Van Els, Cecile A" uniqKey="Van Els C" first="Cécile A." last="Van Els">Cécile A. Van Els</name>
<affiliation>
<nlm:aff id="aff8">Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, the Netherlands</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Locht, Camille" sort="Locht, Camille" uniqKey="Locht C" first="Camille" last="Locht">Camille Locht</name>
<affiliation>
<nlm:aff id="aff4">Institut Pasteur de Lille, Inserm U1019, CNRS UMR8204, University of Lille, Center for Infection and Immunity of Lille, Lille, France</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Hozbor, Daniela" sort="Hozbor, Daniela" uniqKey="Hozbor D" first="Daniela" last="Hozbor">Daniela Hozbor</name>
<affiliation>
<nlm:aff id="aff9">IBBM, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Rodriguez, Maria E" sort="Rodriguez, Maria E" uniqKey="Rodriguez M" first="Maria E." last="Rodriguez">Maria E. Rodriguez</name>
<affiliation>
<nlm:aff id="aff10">CINDEFI (CONICET-UNLP), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina</nlm:aff>
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<idno type="doi">10.1128/CVI.00388-16</idno>
<date when="2016">2016</date>
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<title xml:lang="en" level="a" type="main">Highlights of the 11th International
<named-content content-type="genus-species">Bordetella</named-content>
Symposium: from Basic Biology to Vaccine Development</title>
<author>
<name sortKey="Carbonetti, Nicholas H" sort="Carbonetti, Nicholas H" uniqKey="Carbonetti N" first="Nicholas H." last="Carbonetti">Nicholas H. Carbonetti</name>
<affiliation>
<nlm:aff id="aff1">University of Maryland School of Medicine, Baltimore, Maryland, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Wirsing Von Konig, Carl Heinz" sort="Wirsing Von Konig, Carl Heinz" uniqKey="Wirsing Von Konig C" first="Carl Heinz" last="Wirsing Von König">Carl Heinz Wirsing Von König</name>
<affiliation>
<nlm:aff id="aff2">Labor:Medizin Krefeld MVZ GmbH, Krefeld, Germany</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Lan, Ruiting" sort="Lan, Ruiting" uniqKey="Lan R" first="Ruiting" last="Lan">Ruiting Lan</name>
<affiliation>
<nlm:aff id="aff3">School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Jacob Dubuisson, Francoise" sort="Jacob Dubuisson, Francoise" uniqKey="Jacob Dubuisson F" first="Francoise" last="Jacob-Dubuisson">Francoise Jacob-Dubuisson</name>
<affiliation>
<nlm:aff id="aff4">Institut Pasteur de Lille, Inserm U1019, CNRS UMR8204, University of Lille, Center for Infection and Immunity of Lille, Lille, France</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Cotter, Peggy A" sort="Cotter, Peggy A" uniqKey="Cotter P" first="Peggy A." last="Cotter">Peggy A. Cotter</name>
<affiliation>
<nlm:aff id="aff5">University of North Carolina—Chapel Hill School of Medicine, Chapel Hill, North Carolina, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Deora, Rajendar" sort="Deora, Rajendar" uniqKey="Deora R" first="Rajendar" last="Deora">Rajendar Deora</name>
<affiliation>
<nlm:aff id="aff6">Wake Forest School of Medicine, Winston-Salem, North Carolina, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Merkel, Tod J" sort="Merkel, Tod J" uniqKey="Merkel T" first="Tod J." last="Merkel">Tod J. Merkel</name>
<affiliation>
<nlm:aff id="aff7">Center for Biologics Evaluation and Research, FDA, Silver Spring, Maryland, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Van Els, Cecile A" sort="Van Els, Cecile A" uniqKey="Van Els C" first="Cécile A." last="Van Els">Cécile A. Van Els</name>
<affiliation>
<nlm:aff id="aff8">Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, the Netherlands</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Locht, Camille" sort="Locht, Camille" uniqKey="Locht C" first="Camille" last="Locht">Camille Locht</name>
<affiliation>
<nlm:aff id="aff4">Institut Pasteur de Lille, Inserm U1019, CNRS UMR8204, University of Lille, Center for Infection and Immunity of Lille, Lille, France</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Hozbor, Daniela" sort="Hozbor, Daniela" uniqKey="Hozbor D" first="Daniela" last="Hozbor">Daniela Hozbor</name>
<affiliation>
<nlm:aff id="aff9">IBBM, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Rodriguez, Maria E" sort="Rodriguez, Maria E" uniqKey="Rodriguez M" first="Maria E." last="Rodriguez">Maria E. Rodriguez</name>
<affiliation>
<nlm:aff id="aff10">CINDEFI (CONICET-UNLP), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina</nlm:aff>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Clinical and Vaccine Immunology : CVI</title>
<idno type="ISSN">1556-6811</idno>
<idno type="eISSN">1556-679X</idno>
<imprint>
<date when="2016">2016</date>
</imprint>
</series>
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<front>
<div type="abstract" xml:lang="en">
<p>Pertussis is a severe respiratory disease caused by infection with the bacterial pathogen
<named-content content-type="genus-species">Bordetella pertussis</named-content>
. The disease affects individuals of all ages but is particularly severe and sometimes fatal in unvaccinated young infants. Other
<named-content content-type="genus-species">Bordetella</named-content>
species cause diseases in humans, animals, and birds. Scientific, clinical, public health, vaccine company, and regulatory agency experts on these pathogens and diseases gathered in Buenos Aires, Argentina from 5 to 8 April 2016 for the 11th International
<named-content content-type="genus-species">Bordetella</named-content>
Symposium to discuss recent advances in our understanding of the biology of these organisms, the diseases they cause, and the development of new vaccines and other strategies to prevent these diseases. Highlights of the meeting included pertussis epidemiology in developing nations, genomic analysis of
<named-content content-type="genus-species">Bordetella</named-content>
biology and evolution, regulation of virulence factor expression, new model systems to study
<named-content content-type="genus-species">Bordetella</named-content>
biology and disease, effects of different vaccines on immune responses, maternal immunization as a strategy to prevent newborn disease, and novel vaccine development for pertussis. In addition, the group approved the formation of an International
<named-content content-type="genus-species">Bordetella</named-content>
Society to promote research and information exchange on bordetellae and to organize future meetings. A new Bordetella.org website will also be developed to facilitate these goals.</p>
</div>
</front>
</TEI>
<pmc article-type="review-article">
<pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">Clin Vaccine Immunol</journal-id>
<journal-id journal-id-type="iso-abbrev">Clin. Vaccine Immunol</journal-id>
<journal-id journal-id-type="hwp">cdli</journal-id>
<journal-id journal-id-type="pmc">cvi</journal-id>
<journal-id journal-id-type="publisher-id">CVI</journal-id>
<journal-title-group>
<journal-title>Clinical and Vaccine Immunology : CVI</journal-title>
</journal-title-group>
<issn pub-type="ppub">1556-6811</issn>
<issn pub-type="epub">1556-679X</issn>
<publisher>
<publisher-name>American Society for Microbiology</publisher-name>
<publisher-loc>1752 N St., N.W., Washington, DC</publisher-loc>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">27655886</article-id>
<article-id pub-id-type="pmc">5098017</article-id>
<article-id pub-id-type="publisher-id">00388-16</article-id>
<article-id pub-id-type="doi">10.1128/CVI.00388-16</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Meeting Highlights</subject>
</subj-group>
<subj-group subj-group-type="editorial-class">
<subject>Spotlight</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Highlights of the 11th International
<named-content content-type="genus-species">Bordetella</named-content>
Symposium: from Basic Biology to Vaccine Development</article-title>
<alt-title alt-title-type="running-head">Meeting Highlights</alt-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<name>
<surname>Carbonetti</surname>
<given-names>Nicholas H.</given-names>
</name>
<xref ref-type="aff" rid="aff1">
<sup>a</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Wirsing von König</surname>
<given-names>Carl Heinz</given-names>
</name>
<xref ref-type="aff" rid="aff2">
<sup>b</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Lan</surname>
<given-names>Ruiting</given-names>
</name>
<xref ref-type="aff" rid="aff3">
<sup>c</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<contrib-id contrib-id-type="orcid" authenticated="false">http://orcid.org/0000-0002-5102-1704</contrib-id>
<name>
<surname>Jacob-Dubuisson</surname>
<given-names>Francoise</given-names>
</name>
<xref ref-type="aff" rid="aff4">
<sup>d</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Cotter</surname>
<given-names>Peggy A.</given-names>
</name>
<xref ref-type="aff" rid="aff5">
<sup>e</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Deora</surname>
<given-names>Rajendar</given-names>
</name>
<xref ref-type="aff" rid="aff6">
<sup>f</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Merkel</surname>
<given-names>Tod J.</given-names>
</name>
<xref ref-type="aff" rid="aff7">
<sup>g</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>van Els</surname>
<given-names>Cécile A.</given-names>
</name>
<xref ref-type="aff" rid="aff8">
<sup>h</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Locht</surname>
<given-names>Camille</given-names>
</name>
<xref ref-type="aff" rid="aff4">
<sup>d</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Hozbor</surname>
<given-names>Daniela</given-names>
</name>
<xref ref-type="aff" rid="aff9">
<sup>i</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Rodriguez</surname>
<given-names>Maria E.</given-names>
</name>
<xref ref-type="aff" rid="aff10">
<sup>j</sup>
</xref>
</contrib>
<aff id="aff1">
<label>a</label>
University of Maryland School of Medicine, Baltimore, Maryland, USA</aff>
<aff id="aff2">
<label>b</label>
Labor:Medizin Krefeld MVZ GmbH, Krefeld, Germany</aff>
<aff id="aff3">
<label>c</label>
School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia</aff>
<aff id="aff4">
<label>d</label>
Institut Pasteur de Lille, Inserm U1019, CNRS UMR8204, University of Lille, Center for Infection and Immunity of Lille, Lille, France</aff>
<aff id="aff5">
<label>e</label>
University of North Carolina—Chapel Hill School of Medicine, Chapel Hill, North Carolina, USA</aff>
<aff id="aff6">
<label>f</label>
Wake Forest School of Medicine, Winston-Salem, North Carolina, USA</aff>
<aff id="aff7">
<label>g</label>
Center for Biologics Evaluation and Research, FDA, Silver Spring, Maryland, USA</aff>
<aff id="aff8">
<label>h</label>
Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, the Netherlands</aff>
<aff id="aff9">
<label>i</label>
IBBM, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina</aff>
<aff id="aff10">
<label>j</label>
CINDEFI (CONICET-UNLP), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina</aff>
</contrib-group>
<contrib-group>
<contrib contrib-type="editor">
<name>
<surname>Burns</surname>
<given-names>D. L.</given-names>
</name>
<role>Editor</role>
</contrib>
<aff>Food and Drug Administration</aff>
</contrib-group>
<author-notes>
<corresp id="cor1">Address correspondence to Nicholas H. Carbonetti,
<email>ncarbonetti@som.umaryland.edu</email>
.</corresp>
<fn fn-type="other">
<p>
<bold>Citation</bold>
Carbonetti NH, Wirsing von König CH, Lan R, Jacob-Dubuisson F, Cotter PA, Deora R, Merkel TJ, van Els CA, Locht C, Hozbor D, Rodriguez ME. 2016. Highlights of the 11th International
<named-content content-type="genus-species">Bordetella</named-content>
Symposium: from basic biology to vaccine development. Clin Vaccine Immunol 23:842–850. doi:
<ext-link ext-link-type="uri" xlink:href="http://dx.doi.org/10.1128/CVI.00388-16">10.1128/CVI.00388-16</ext-link>
.</p>
</fn>
</author-notes>
<pub-date pub-type="epreprint">
<day>21</day>
<month>9</month>
<year>2016</year>
</pub-date>
<pub-date pub-type="epub">
<day>4</day>
<month>11</month>
<year>2016</year>
</pub-date>
<pub-date pub-type="collection">
<month>11</month>
<year>2016</year>
</pub-date>
<volume>23</volume>
<issue>11</issue>
<fpage>842</fpage>
<lpage>850</lpage>
<permissions>
<copyright-statement>Copyright © 2016, American Society for Microbiology. All Rights Reserved.</copyright-statement>
<copyright-year>2016</copyright-year>
<copyright-holder>American Society for Microbiology</copyright-holder>
</permissions>
<self-uri content-type="pdf" xlink:href="zcd01116000842.pdf"></self-uri>
<abstract>
<p>Pertussis is a severe respiratory disease caused by infection with the bacterial pathogen
<named-content content-type="genus-species">Bordetella pertussis</named-content>
. The disease affects individuals of all ages but is particularly severe and sometimes fatal in unvaccinated young infants. Other
<named-content content-type="genus-species">Bordetella</named-content>
species cause diseases in humans, animals, and birds. Scientific, clinical, public health, vaccine company, and regulatory agency experts on these pathogens and diseases gathered in Buenos Aires, Argentina from 5 to 8 April 2016 for the 11th International
<named-content content-type="genus-species">Bordetella</named-content>
Symposium to discuss recent advances in our understanding of the biology of these organisms, the diseases they cause, and the development of new vaccines and other strategies to prevent these diseases. Highlights of the meeting included pertussis epidemiology in developing nations, genomic analysis of
<named-content content-type="genus-species">Bordetella</named-content>
biology and evolution, regulation of virulence factor expression, new model systems to study
<named-content content-type="genus-species">Bordetella</named-content>
biology and disease, effects of different vaccines on immune responses, maternal immunization as a strategy to prevent newborn disease, and novel vaccine development for pertussis. In addition, the group approved the formation of an International
<named-content content-type="genus-species">Bordetella</named-content>
Society to promote research and information exchange on bordetellae and to organize future meetings. A new Bordetella.org website will also be developed to facilitate these goals.</p>
</abstract>
<funding-group>
<award-group id="award1">
<funding-source id="gs1">HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID)
<named-content content-type="funder-id">http://dx.doi.org/10.13039/100000060</named-content>
</funding-source>
<award-id rid="gs1">R21 AI117095</award-id>
<award-id rid="gs1">R01 AI101055</award-id>
<award-id rid="gs1">R21 AI119566</award-id>
<principal-award-recipient>Nicholas H. Carbonetti</principal-award-recipient>
</award-group>
<award-group id="award2">
<funding-source id="gs2">HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID)
<named-content content-type="funder-id">http://dx.doi.org/10.13039/100000060</named-content>
</funding-source>
<award-id rid="gs2">R01 AI125560</award-id>
<principal-award-recipient>Rajendar Deora</principal-award-recipient>
</award-group>
<award-group id="award3">
<funding-source id="gs3">HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID)
<named-content content-type="funder-id">http://dx.doi.org/10.13039/100000060</named-content>
</funding-source>
<award-id rid="gs3">R21 AI126147</award-id>
<principal-award-recipient>Rajendar Deora</principal-award-recipient>
</award-group>
<award-group id="award4">
<funding-source id="gs4">HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID)
<named-content content-type="funder-id">http://dx.doi.org/10.13039/100000060</named-content>
</funding-source>
<award-id rid="gs4">R01 AI094991</award-id>
<principal-award-recipient>Peggy A. Cotter</principal-award-recipient>
</award-group>
<award-group id="award5">
<funding-source id="gs5">the National Health and Medical Research Council (NHMRC)
<named-content content-type="funder-id">http://dx.doi.org/10.13039/100000060</named-content>
</funding-source>
<award-id rid="gs5">APP1011942</award-id>
<principal-award-recipient>Ruiting Lan</principal-award-recipient>
</award-group>
<award-group id="award6">
<funding-source id="gs6">Agencia Nacional de Promoción Científica y Técnológica (ANCPyT)
<named-content content-type="funder-id">http://dx.doi.org/10.13039/100000060</named-content>
</funding-source>
<award-id rid="gs6">PICT2012/2719</award-id>
<award-id rid="gs6">PICT2014/3617</award-id>
<principal-award-recipient>Daniela Hozbor</principal-award-recipient>
</award-group>
<award-group id="award7">
<funding-source id="gs7">L' Agence Nationale de la Recherche
<named-content content-type="funder-id">http://dx.doi.org/10.13039/100000060</named-content>
</funding-source>
<award-id rid="gs7">ANR-13-BSV8-0002-01</award-id>
<principal-award-recipient>F. Jacob-Dubuisson</principal-award-recipient>
</award-group>
<award-group id="award8">
<funding-source id="gs8">the National Agency for Scientific and Technological Promotion (MINCyT)
<named-content content-type="funder-id">http://dx.doi.org/10.13039/100000060</named-content>
</funding-source>
<award-id rid="gs7">PICT 2013 1937</award-id>
<principal-award-recipient>Maria Eugenia Rodriguez</principal-award-recipient>
</award-group>
<funding-statement>The symposium was funded in part by conference grant RC 2015 0031 from the National Agency for Scientific and Technological Promotion (MINCyT) (to Maria Eugenia Rodriguez) and by an R13 conference grant from the National Institute of Allergy and Infectious Diseases, NIH (to Eric Hewlett).</funding-statement>
</funding-group>
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