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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Complicated intra-abdominal infections in a worldwide context: an observational prospective study (CIAOW Study)</title><author><name sortKey="Sartelli, Massimo" sort="Sartelli, Massimo" uniqKey="Sartelli M" first="Massimo" last="Sartelli">Massimo Sartelli</name><affiliation><nlm:aff id="I1">Department of Surgery, Macerata Hospital, Macerata, Italy</nlm:aff></affiliation></author><author><name sortKey="Catena, Fausto" sort="Catena, Fausto" uniqKey="Catena F" first="Fausto" last="Catena">Fausto Catena</name><affiliation><nlm:aff id="I2">Emergency Surgery, Maggiore Parma Hospital, Parma, Italy</nlm:aff></affiliation></author><author><name sortKey="Ansaloni, Luca" sort="Ansaloni, Luca" uniqKey="Ansaloni L" first="Luca" last="Ansaloni">Luca Ansaloni</name><affiliation><nlm:aff id="I3">Department of General Surgery, Ospedali Riuniti, Bergamo, Italy</nlm:aff></affiliation></author><author><name sortKey="Moore, Ernest" sort="Moore, Ernest" uniqKey="Moore E" first="Ernest" last="Moore">Ernest Moore</name><affiliation><nlm:aff id="I4">Department of Surgery, Denver Health Medical Center, Denver, CO, USA</nlm:aff></affiliation></author><author><name sortKey="Malangoni, Mark" sort="Malangoni, Mark" uniqKey="Malangoni M" first="Mark" last="Malangoni">Mark Malangoni</name><affiliation><nlm:aff id="I5">American Board of Surgery, Philadelphia, PA, USA</nlm:aff></affiliation></author><author><name sortKey="Velmahos, George" sort="Velmahos, George" uniqKey="Velmahos G" first="George" last="Velmahos">George Velmahos</name><affiliation><nlm:aff id="I6">Harvard Medical School, Division of Trauma, Emergency Surgery and Surgical Critical Care Massachusetts General Hospital, Boston, MA, USA</nlm:aff></affiliation></author><author><name sortKey="Coimbra, Raul" sort="Coimbra, Raul" uniqKey="Coimbra R" first="Raul" last="Coimbra">Raul Coimbra</name><affiliation><nlm:aff id="I7">Department of Surgery, UC San Diego Health System, San Diego, CA, USA</nlm:aff></affiliation></author><author><name sortKey="Koike, Kaoru" sort="Koike, Kaoru" uniqKey="Koike K" first="Kaoru" last="Koike">Kaoru Koike</name><affiliation><nlm:aff id="I8">Department of Primary Care & Emergency Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan</nlm:aff></affiliation></author><author><name sortKey="Leppaniemi, Ari" sort="Leppaniemi, Ari" uniqKey="Leppaniemi A" first="Ari" last="Leppaniemi">Ari Leppaniemi</name><affiliation><nlm:aff id="I9">Department of Abdominal Surgery, University Hospital Meilahti, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Biffl, Walter" sort="Biffl, Walter" uniqKey="Biffl W" first="Walter" last="Biffl">Walter Biffl</name><affiliation><nlm:aff id="I4">Department of Surgery, Denver Health Medical Center, Denver, CO, USA</nlm:aff></affiliation></author><author><name sortKey="Balogh, Zsolt" sort="Balogh, Zsolt" uniqKey="Balogh Z" first="Zsolt" last="Balogh">Zsolt Balogh</name><affiliation><nlm:aff id="I10">Department of Surgery, University of Newcastle, Newcastle, NSW, Australia</nlm:aff></affiliation></author><author><name sortKey="Bendinelli, Cino" sort="Bendinelli, Cino" uniqKey="Bendinelli C" first="Cino" last="Bendinelli">Cino Bendinelli</name><affiliation><nlm:aff id="I10">Department of Surgery, University of Newcastle, Newcastle, NSW, Australia</nlm:aff></affiliation></author><author><name sortKey="Gupta, Sanjay" sort="Gupta, Sanjay" uniqKey="Gupta S" first="Sanjay" last="Gupta">Sanjay Gupta</name><affiliation><nlm:aff id="I11">Department of Surgery, Govt Medical College and Hospital, Chandigarh, India</nlm:aff></affiliation></author><author><name sortKey="Kluger, Yoram" sort="Kluger, Yoram" uniqKey="Kluger Y" first="Yoram" last="Kluger">Yoram Kluger</name><affiliation><nlm:aff id="I12">Department of General Surgery, Rambam Health Care Campus, Haifa, Israel</nlm:aff></affiliation></author><author><name sortKey="Agresta, Ferdinando" sort="Agresta, Ferdinando" uniqKey="Agresta F" first="Ferdinando" last="Agresta">Ferdinando Agresta</name><affiliation><nlm:aff id="I13">Department of Surgery, Adria Hospital, Adria, Italy</nlm:aff></affiliation></author><author><name sortKey="Di Saverio, Salomone" sort="Di Saverio, Salomone" uniqKey="Di Saverio S" first="Salomone" last="Di Saverio">Salomone Di Saverio</name><affiliation><nlm:aff id="I14">Trauma Surgery Unit, Maggiore Hospital, Bologna, Italy</nlm:aff></affiliation></author><author><name sortKey="Tugnoli, Gregorio" sort="Tugnoli, Gregorio" uniqKey="Tugnoli G" first="Gregorio" last="Tugnoli">Gregorio Tugnoli</name><affiliation><nlm:aff id="I14">Trauma Surgery Unit, Maggiore Hospital, Bologna, Italy</nlm:aff></affiliation></author><author><name sortKey="Jovine, Elio" sort="Jovine, Elio" uniqKey="Jovine E" first="Elio" last="Jovine">Elio Jovine</name><affiliation><nlm:aff id="I15">Department of Surgery, Maggiore Hospital, Bologna, Italy</nlm:aff></affiliation></author><author><name sortKey="Ordonez, Carlos" sort="Ordonez, Carlos" uniqKey="Ordonez C" first="Carlos" last="Ordonez">Carlos Ordonez</name><affiliation><nlm:aff id="I16">Department of Surgery, Universidad del Valle, Fundacion Valle del Lili, Cali, Colombia</nlm:aff></affiliation></author><author><name sortKey="Gomes, Carlos Augusto" sort="Gomes, Carlos Augusto" uniqKey="Gomes C" first="Carlos Augusto" last="Gomes">Carlos Augusto Gomes</name><affiliation><nlm:aff id="I17">Department of Surgery, Monte Sinai Hospital, Juiz de Fora, Brazil</nlm:aff></affiliation></author><author><name sortKey="Junior, Gerson Alves Pereira" sort="Junior, Gerson Alves Pereira" uniqKey="Junior G" first="Gerson Alves Pereira" last="Junior">Gerson Alves Pereira Junior</name><affiliation><nlm:aff id="I18">Emergency Unit, Department of Surgery, Ribeirão Preto, Brazil</nlm:aff></affiliation></author><author><name sortKey="Yuan, Kuo Ching" sort="Yuan, Kuo Ching" uniqKey="Yuan K" first="Kuo-Ching" last="Yuan">Kuo-Ching Yuan</name><affiliation><nlm:aff id="I19">Department of Surgery, Chang Gung Memorial Hospital, Taoyuan, Taiwan</nlm:aff></affiliation></author><author><name sortKey="Bala, Miklosh" sort="Bala, Miklosh" uniqKey="Bala M" first="Miklosh" last="Bala">Miklosh Bala</name><affiliation><nlm:aff id="I20">Department of General Surgery, Hadassah Medical Center, Jerusalem, Israel</nlm:aff></affiliation></author><author><name sortKey="Peev, Miroslav P" sort="Peev, Miroslav P" uniqKey="Peev M" first="Miroslav P" last="Peev">Miroslav P. Peev</name><affiliation><nlm:aff id="I6">Harvard Medical School, Division of Trauma, Emergency Surgery and Surgical Critical Care Massachusetts General Hospital, Boston, MA, USA</nlm:aff></affiliation></author><author><name sortKey="Cui, Yunfeng" sort="Cui, Yunfeng" uniqKey="Cui Y" first="Yunfeng" last="Cui">Yunfeng Cui</name><affiliation><nlm:aff id="I21">Department of Surgery, Tianjin Nankai Hospital, Nankai Clinical School of Medicine, Tianjin Medical University, Tianjin, China</nlm:aff></affiliation></author><author><name sortKey="Marwah, Sanjay" sort="Marwah, Sanjay" uniqKey="Marwah S" first="Sanjay" last="Marwah">Sanjay Marwah</name><affiliation><nlm:aff id="I22">Department of Surgery, Pt BDS Post-graduate Institute of Medical Sciences, Rohtak, India</nlm:aff></affiliation></author><author><name sortKey="Zachariah, Sanoop" sort="Zachariah, Sanoop" uniqKey="Zachariah S" first="Sanoop" last="Zachariah">Sanoop Zachariah</name><affiliation><nlm:aff id="I23">Department of Surgery, MOSC medical college, Cochin, India</nlm:aff></affiliation></author><author><name sortKey="Sakakushev, Boris" sort="Sakakushev, Boris" uniqKey="Sakakushev B" first="Boris" last="Sakakushev">Boris Sakakushev</name><affiliation><nlm:aff id="I24">First Clinic of General Surgery, University Hospital /UMBAL/ St George Plovdiv, Plovdiv, Bulgaria</nlm:aff></affiliation><affiliation><nlm:aff id="I25">General Surgery Clinic, Medical University/University Hospital St.George, Plovdiv, Bulgaria</nlm:aff></affiliation></author><author><name sortKey="Kong, Victor" sort="Kong, Victor" uniqKey="Kong V" first="Victor" last="Kong">Victor Kong</name><affiliation><nlm:aff id="I26">Department of Surgery, Edendale Hospital, Pietermaritzburg, Republic of South Africa</nlm:aff></affiliation></author><author><name sortKey="Ahmed, Adamu" sort="Ahmed, Adamu" uniqKey="Ahmed A" first="Adamu" last="Ahmed">Adamu Ahmed</name><affiliation><nlm:aff id="I27">Department of Surgery, Ahmadu Bello University Teaching Hospital Zaria, Kaduna, Nigeria</nlm:aff></affiliation></author><author><name sortKey="Abbas, Ashraf" sort="Abbas, Ashraf" uniqKey="Abbas A" first="Ashraf" last="Abbas">Ashraf Abbas</name><affiliation><nlm:aff id="I28">Department of Surgery, Mansoura University Hospital, Mansoura, Egypt</nlm:aff></affiliation></author><author><name sortKey="Gonsaga, Ricardo Alessandro Teixeira" sort="Gonsaga, Ricardo Alessandro Teixeira" uniqKey="Gonsaga R" first="Ricardo Alessandro Teixeira" last="Gonsaga">Ricardo Alessandro Teixeira Gonsaga</name><affiliation><nlm:aff id="I29">Department of Surgery, Faculdades Integradas Padre Albino, Catanduva, Brazil</nlm:aff></affiliation></author><author><name sortKey="Guercioni, Gianluca" sort="Guercioni, Gianluca" uniqKey="Guercioni G" first="Gianluca" last="Guercioni">Gianluca Guercioni</name><affiliation><nlm:aff id="I30">Department of Surgery, Mazzoni Hospital, Ascoli Piceno, Italy</nlm:aff></affiliation></author><author><name sortKey="Vettoretto, Nereo" sort="Vettoretto, Nereo" uniqKey="Vettoretto N" first="Nereo" last="Vettoretto">Nereo Vettoretto</name><affiliation><nlm:aff id="I31">Department of Surgery, Mellini Hospital, Chiari (BS), Italy</nlm:aff></affiliation></author><author><name sortKey="Poiasina, Elia" sort="Poiasina, Elia" uniqKey="Poiasina E" first="Elia" last="Poiasina">Elia Poiasina</name><affiliation><nlm:aff id="I3">Department of General Surgery, Ospedali Riuniti, Bergamo, Italy</nlm:aff></affiliation></author><author><name sortKey="Ben Ishay, Offir" sort="Ben Ishay, Offir" uniqKey="Ben Ishay O" first="Offir" last="Ben-Ishay">Offir Ben-Ishay</name><affiliation><nlm:aff id="I12">Department of General Surgery, Rambam Health Care Campus, Haifa, Israel</nlm:aff></affiliation></author><author><name sortKey="Diaz Nieto, Rafael" sort="Diaz Nieto, Rafael" uniqKey="Diaz Nieto R" first="Rafael" last="Díaz-Nieto">Rafael Díaz-Nieto</name><affiliation><nlm:aff id="I32">Department of General and Digestive Surgery, Virgen de la Victoria, University Hospital, Malaga, Spain</nlm:aff></affiliation></author><author><name sortKey="Massalou, Damien" sort="Massalou, Damien" uniqKey="Massalou D" first="Damien" last="Massalou">Damien Massalou</name><affiliation><nlm:aff id="I33">Department of General Surgery and Surgical Oncology, Université de Nice Sophia-Antipolis, Universitary Hospital of Nice, Nice, France</nlm:aff></affiliation></author><author><name sortKey="Skrovina, Matej" sort="Skrovina, Matej" uniqKey="Skrovina M" first="Matej" last="Skrovina">Matej Skrovina</name><affiliation><nlm:aff id="I34">Department of Surgery, Hospital and Oncological Centre, Novy Jicin, Czech Republic</nlm:aff></affiliation></author><author><name sortKey="Gerych, Ihor" sort="Gerych, Ihor" uniqKey="Gerych I" first="Ihor" last="Gerych">Ihor Gerych</name><affiliation><nlm:aff id="I35">Department of General Surgery, Lviv Emergency Hospital, Lviv, Ukraine</nlm:aff></affiliation></author><author><name sortKey="Augustin, Goran" sort="Augustin, Goran" uniqKey="Augustin G" first="Goran" last="Augustin">Goran Augustin</name><affiliation><nlm:aff id="I36">Department of Surgery, University Hospital Center Zagreb, Zagreb, Croatia</nlm:aff></affiliation></author><author><name sortKey="Kenig, Jakub" sort="Kenig, Jakub" uniqKey="Kenig J" first="Jakub" last="Kenig">Jakub Kenig</name><affiliation><nlm:aff id="I37">3rd Department of General Surger Jagiellonian Univeristy, Narutowicz Hospital, Krakow, Poland</nlm:aff></affiliation></author><author><name sortKey="Khokha, Vladimir" sort="Khokha, Vladimir" uniqKey="Khokha V" first="Vladimir" last="Khokha">Vladimir Khokha</name><affiliation><nlm:aff id="I38">Department of Surgery, Mozyr City Hospital, Mozyr, Belarus</nlm:aff></affiliation></author><author><name sortKey="Trana, Cristian" sort="Trana, Cristian" uniqKey="Trana C" first="Cristian" last="Tranà">Cristian Tranà</name><affiliation><nlm:aff id="I39">Department of Surgery, Ancona University, Ancona, Italy</nlm:aff></affiliation></author><author><name sortKey="Kok, Kenneth Yuh Yen" sort="Kok, Kenneth Yuh Yen" uniqKey="Kok K" first="Kenneth Yuh Yen" last="Kok">Kenneth Yuh Yen Kok</name><affiliation><nlm:aff id="I40">Department of Surgery, Ripas Hospital, Bandar Seri Begawan, Brunei</nlm:aff></affiliation></author><author><name sortKey="Mefire, Alain Chichom" sort="Mefire, Alain Chichom" uniqKey="Mefire A" first="Alain Chichom" last="Mefire">Alain Chichom Mefire</name><affiliation><nlm:aff id="I41">Clinical Sciences, Regional Hospitals Limbe and Buea, Limbe, Cameroon</nlm:aff></affiliation></author><author><name sortKey="Lee, Jae Gil" sort="Lee, Jae Gil" uniqKey="Lee J" first="Jae Gil" last="Lee">Jae Gil Lee</name><affiliation><nlm:aff id="I42">Department of Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea</nlm:aff></affiliation></author><author><name sortKey="Hong, Suk Kyung" sort="Hong, Suk Kyung" uniqKey="Hong S" first="Suk-Kyung" last="Hong">Suk-Kyung Hong</name><affiliation><nlm:aff id="I43">Division of Trauma and Surgical Critical Care, Department of Surgery, University of Ulsan, Seoul, Republic of Korea</nlm:aff></affiliation></author><author><name sortKey="Lohse, Helmut Alfredo Segovia" sort="Lohse, Helmut Alfredo Segovia" uniqKey="Lohse H" first="Helmut Alfredo Segovia" last="Lohse">Helmut Alfredo Segovia Lohse</name><affiliation><nlm:aff id="I44">II Cátedra de Clínica Quirúrgica, Hospital de Clínicas, Asuncion, Paraguay</nlm:aff></affiliation></author><author><name sortKey="Ghnnam, Wagih" sort="Ghnnam, Wagih" uniqKey="Ghnnam W" first="Wagih" last="Ghnnam">Wagih Ghnnam</name><affiliation><nlm:aff id="I45">Department of Surgery, Khamis Mushayt General Hospital, Khamis Mushayt, Saudi Arabia</nlm:aff></affiliation></author><author><name sortKey="Verni, Alfredo" sort="Verni, Alfredo" uniqKey="Verni A" first="Alfredo" last="Verni">Alfredo Verni</name><affiliation><nlm:aff id="I46">Department of Surgery, Cutral Co Clinic, Neuquen, Argentina</nlm:aff></affiliation></author><author><name sortKey="Lohsiriwat, Varut" sort="Lohsiriwat, Varut" uniqKey="Lohsiriwat V" first="Varut" last="Lohsiriwat">Varut Lohsiriwat</name><affiliation><nlm:aff id="I47">Department of Surgery, Faculty of Medicine Siriraj Hospital, Bangkok, Thailand</nlm:aff></affiliation></author><author><name sortKey="Siribumrungwong, Boonying" sort="Siribumrungwong, Boonying" uniqKey="Siribumrungwong B" first="Boonying" last="Siribumrungwong">Boonying Siribumrungwong</name><affiliation><nlm:aff id="I48">Department of Surgery, Thammasat University Hospital, Pathumthani, Thailand</nlm:aff></affiliation></author><author><name sortKey="Tavares, Alberto" sort="Tavares, Alberto" uniqKey="Tavares A" first="Alberto" last="Tavares">Alberto Tavares</name><affiliation><nlm:aff id="I49">Department of Surgery, Hospital Regional de Alta Especialidad del Bajio, Leon, Mexico</nlm:aff></affiliation></author><author><name sortKey="Baiocchi, Gianluca" sort="Baiocchi, Gianluca" uniqKey="Baiocchi G" first="Gianluca" last="Baiocchi">Gianluca Baiocchi</name><affiliation><nlm:aff id="I50">Department of Clinical and Experimental Sciences, Brescia University, Brescia, Italy</nlm:aff></affiliation></author><author><name sortKey="Das, Koray" sort="Das, Koray" uniqKey="Das K" first="Koray" last="Das">Koray Das</name><affiliation><nlm:aff id="I51">General Surgery, Adana Numune Training and Research Hospital, Adana, Turkey</nlm:aff></affiliation></author><author><name sortKey="Jarry, Julien" sort="Jarry, Julien" uniqKey="Jarry J" first="Julien" last="Jarry">Julien Jarry</name><affiliation><nlm:aff id="I52">Visceral Surgery, Military Hospital Desgenettes, Lyon, France</nlm:aff></affiliation></author><author><name sortKey="Zida, Maurice" sort="Zida, Maurice" uniqKey="Zida M" first="Maurice" last="Zida">Maurice Zida</name><affiliation><nlm:aff id="I53">Visceral Surgery, Teaching Hospital Yalgado Ouedraogo, Ouagadougou, Burkina Faso</nlm:aff></affiliation></author><author><name sortKey="Sato, Norio" sort="Sato, Norio" uniqKey="Sato N" first="Norio" last="Sato">Norio Sato</name><affiliation><nlm:aff id="I8">Department of Primary Care & Emergency Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan</nlm:aff></affiliation></author><author><name sortKey="Murata, Kiyoshi" sort="Murata, Kiyoshi" uniqKey="Murata K" first="Kiyoshi" last="Murata">Kiyoshi Murata</name><affiliation><nlm:aff id="I54">Department of Acute and Critical care medicine, Tokyo Medical and Dental University, Tokyo, Japan</nlm:aff></affiliation></author><author><name sortKey="Shoko, Tomohisa" sort="Shoko, Tomohisa" uniqKey="Shoko T" first="Tomohisa" last="Shoko">Tomohisa Shoko</name><affiliation><nlm:aff id="I55">The Shock Trauma and Emergency Medical Center, Matsudo City Hospital, Chiba, Japan</nlm:aff></affiliation></author><author><name sortKey="Irahara, Takayuki" sort="Irahara, Takayuki" uniqKey="Irahara T" first="Takayuki" last="Irahara">Takayuki Irahara</name><affiliation><nlm:aff id="I56">Emergency and Critical Care Center of Nippon Medical School, Tama-Nagayama Hospital, Tokyo, Japan</nlm:aff></affiliation></author><author><name sortKey="Hamedelneel, Ahmed O" sort="Hamedelneel, Ahmed O" uniqKey="Hamedelneel A" first="Ahmed O" last="Hamedelneel">Ahmed O. Hamedelneel</name><affiliation><nlm:aff id="I57">Department of Surgery, Our Lady of Lourdes Hospital, Drogheda, Ireland</nlm:aff></affiliation></author><author><name sortKey="Naidoo, Noel" sort="Naidoo, Noel" uniqKey="Naidoo N" first="Noel" last="Naidoo">Noel Naidoo</name><affiliation><nlm:aff id="I58">Department of Surgery, Port Shepstone Hospital, Port Shepstone, South Africa</nlm:aff></affiliation></author><author><name sortKey="Adesunkanmi, Abdul Rashid Kayode" sort="Adesunkanmi, Abdul Rashid Kayode" uniqKey="Adesunkanmi A" first="Abdul Rashid Kayode" last="Adesunkanmi">Abdul Rashid Kayode Adesunkanmi</name><affiliation><nlm:aff id="I59">Department of Surgery, College of Health Sciences, Obafemi Awolowo University Hospital, Ile-Ife, Nigeria</nlm:aff></affiliation></author><author><name sortKey="Kobe, Yoshiro" sort="Kobe, Yoshiro" uniqKey="Kobe Y" first="Yoshiro" last="Kobe">Yoshiro Kobe</name><affiliation><nlm:aff id="I60">Department of Emergency and Critical Care Medicine, Chiba University Hospital, Chiba, Japan</nlm:aff></affiliation></author><author><name sortKey="Attri, Ak" sort="Attri, Ak" uniqKey="Attri A" first="Ak" last="Attri">Ak Attri</name><affiliation><nlm:aff id="I11">Department of Surgery, Govt Medical College and Hospital, Chandigarh, India</nlm:aff></affiliation></author><author><name sortKey="Sharma, Rajeev" sort="Sharma, Rajeev" uniqKey="Sharma R" first="Rajeev" last="Sharma">Rajeev Sharma</name><affiliation><nlm:aff id="I11">Department of Surgery, Govt Medical College and Hospital, Chandigarh, India</nlm:aff></affiliation></author><author><name sortKey="Coccolini, Federico" sort="Coccolini, Federico" uniqKey="Coccolini F" first="Federico" last="Coccolini">Federico Coccolini</name><affiliation><nlm:aff id="I3">Department of General Surgery, Ospedali Riuniti, Bergamo, Italy</nlm:aff></affiliation></author><author><name sortKey="El Zalabany, Tamer" sort="El Zalabany, Tamer" uniqKey="El Zalabany T" first="Tamer" last="El Zalabany">Tamer El Zalabany</name><affiliation><nlm:aff id="I61">Department of Surgery, Bahrain Defence Force Hospital, Manama, Bahrain</nlm:aff></affiliation></author><author><name sortKey="Khalifa, Khalid Al" sort="Khalifa, Khalid Al" uniqKey="Khalifa K" first="Khalid Al" last="Khalifa">Khalid Al Khalifa</name><affiliation><nlm:aff id="I61">Department of Surgery, Bahrain Defence Force Hospital, Manama, Bahrain</nlm:aff></affiliation></author><author><name sortKey="Sanjuan, Juan" sort="Sanjuan, Juan" uniqKey="Sanjuan J" first="Juan" last="Sanjuan">Juan Sanjuan</name><affiliation><nlm:aff id="I16">Department of Surgery, Universidad del Valle, Fundacion Valle del Lili, Cali, Colombia</nlm:aff></affiliation></author><author><name sortKey="Barnabe, Rita" sort="Barnabe, Rita" uniqKey="Barnabe R" first="Rita" last="Barnabé">Rita Barnabé</name><affiliation><nlm:aff id="I15">Department of Surgery, Maggiore Hospital, Bologna, Italy</nlm:aff></affiliation></author><author><name sortKey="Ishii, Wataru" sort="Ishii, Wataru" uniqKey="Ishii W" first="Wataru" last="Ishii">Wataru Ishii</name><affiliation><nlm:aff id="I62">Department of Emergency Medicine, Kyoto Second Red Cross Hospital, Kyoto, Japan</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">23286785</idno><idno type="pmc">3538624</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538624</idno><idno type="RBID">PMC:3538624</idno><idno type="doi">10.1186/1749-7922-8-1</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">002E67</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002E67</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Complicated intra-abdominal infections in a worldwide context: an observational prospective study (CIAOW Study)</title><author><name sortKey="Sartelli, Massimo" sort="Sartelli, Massimo" uniqKey="Sartelli M" first="Massimo" last="Sartelli">Massimo Sartelli</name><affiliation><nlm:aff id="I1">Department of Surgery, Macerata Hospital, Macerata, Italy</nlm:aff></affiliation></author><author><name sortKey="Catena, Fausto" sort="Catena, Fausto" uniqKey="Catena F" first="Fausto" last="Catena">Fausto Catena</name><affiliation><nlm:aff id="I2">Emergency Surgery, Maggiore Parma Hospital, Parma, Italy</nlm:aff></affiliation></author><author><name sortKey="Ansaloni, Luca" sort="Ansaloni, Luca" uniqKey="Ansaloni L" first="Luca" last="Ansaloni">Luca Ansaloni</name><affiliation><nlm:aff id="I3">Department of General Surgery, Ospedali Riuniti, Bergamo, Italy</nlm:aff></affiliation></author><author><name sortKey="Moore, Ernest" sort="Moore, Ernest" uniqKey="Moore E" first="Ernest" last="Moore">Ernest Moore</name><affiliation><nlm:aff id="I4">Department of Surgery, Denver Health Medical Center, Denver, CO, USA</nlm:aff></affiliation></author><author><name sortKey="Malangoni, Mark" sort="Malangoni, Mark" uniqKey="Malangoni M" first="Mark" last="Malangoni">Mark Malangoni</name><affiliation><nlm:aff id="I5">American Board of Surgery, Philadelphia, PA, USA</nlm:aff></affiliation></author><author><name sortKey="Velmahos, George" sort="Velmahos, George" uniqKey="Velmahos G" first="George" last="Velmahos">George Velmahos</name><affiliation><nlm:aff id="I6">Harvard Medical School, Division of Trauma, Emergency Surgery and Surgical Critical Care Massachusetts General Hospital, Boston, MA, USA</nlm:aff></affiliation></author><author><name sortKey="Coimbra, Raul" sort="Coimbra, Raul" uniqKey="Coimbra R" first="Raul" last="Coimbra">Raul Coimbra</name><affiliation><nlm:aff id="I7">Department of Surgery, UC San Diego Health System, San Diego, CA, USA</nlm:aff></affiliation></author><author><name sortKey="Koike, Kaoru" sort="Koike, Kaoru" uniqKey="Koike K" first="Kaoru" last="Koike">Kaoru Koike</name><affiliation><nlm:aff id="I8">Department of Primary Care & Emergency Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan</nlm:aff></affiliation></author><author><name sortKey="Leppaniemi, Ari" sort="Leppaniemi, Ari" uniqKey="Leppaniemi A" first="Ari" last="Leppaniemi">Ari Leppaniemi</name><affiliation><nlm:aff id="I9">Department of Abdominal Surgery, University Hospital Meilahti, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Biffl, Walter" sort="Biffl, Walter" uniqKey="Biffl W" first="Walter" last="Biffl">Walter Biffl</name><affiliation><nlm:aff id="I4">Department of Surgery, Denver Health Medical Center, Denver, CO, USA</nlm:aff></affiliation></author><author><name sortKey="Balogh, Zsolt" sort="Balogh, Zsolt" uniqKey="Balogh Z" first="Zsolt" last="Balogh">Zsolt Balogh</name><affiliation><nlm:aff id="I10">Department of Surgery, University of Newcastle, Newcastle, NSW, Australia</nlm:aff></affiliation></author><author><name sortKey="Bendinelli, Cino" sort="Bendinelli, Cino" uniqKey="Bendinelli C" first="Cino" last="Bendinelli">Cino Bendinelli</name><affiliation><nlm:aff id="I10">Department of Surgery, University of Newcastle, Newcastle, NSW, Australia</nlm:aff></affiliation></author><author><name sortKey="Gupta, Sanjay" sort="Gupta, Sanjay" uniqKey="Gupta S" first="Sanjay" last="Gupta">Sanjay Gupta</name><affiliation><nlm:aff id="I11">Department of Surgery, Govt Medical College and Hospital, Chandigarh, India</nlm:aff></affiliation></author><author><name sortKey="Kluger, Yoram" sort="Kluger, Yoram" uniqKey="Kluger Y" first="Yoram" last="Kluger">Yoram Kluger</name><affiliation><nlm:aff id="I12">Department of General Surgery, Rambam Health Care Campus, Haifa, Israel</nlm:aff></affiliation></author><author><name sortKey="Agresta, Ferdinando" sort="Agresta, Ferdinando" uniqKey="Agresta F" first="Ferdinando" last="Agresta">Ferdinando Agresta</name><affiliation><nlm:aff id="I13">Department of Surgery, Adria Hospital, Adria, Italy</nlm:aff></affiliation></author><author><name sortKey="Di Saverio, Salomone" sort="Di Saverio, Salomone" uniqKey="Di Saverio S" first="Salomone" last="Di Saverio">Salomone Di Saverio</name><affiliation><nlm:aff id="I14">Trauma Surgery Unit, Maggiore Hospital, Bologna, Italy</nlm:aff></affiliation></author><author><name sortKey="Tugnoli, Gregorio" sort="Tugnoli, Gregorio" uniqKey="Tugnoli G" first="Gregorio" last="Tugnoli">Gregorio Tugnoli</name><affiliation><nlm:aff id="I14">Trauma Surgery Unit, Maggiore Hospital, Bologna, Italy</nlm:aff></affiliation></author><author><name sortKey="Jovine, Elio" sort="Jovine, Elio" uniqKey="Jovine E" first="Elio" last="Jovine">Elio Jovine</name><affiliation><nlm:aff id="I15">Department of Surgery, Maggiore Hospital, Bologna, Italy</nlm:aff></affiliation></author><author><name sortKey="Ordonez, Carlos" sort="Ordonez, Carlos" uniqKey="Ordonez C" first="Carlos" last="Ordonez">Carlos Ordonez</name><affiliation><nlm:aff id="I16">Department of Surgery, Universidad del Valle, Fundacion Valle del Lili, Cali, Colombia</nlm:aff></affiliation></author><author><name sortKey="Gomes, Carlos Augusto" sort="Gomes, Carlos Augusto" uniqKey="Gomes C" first="Carlos Augusto" last="Gomes">Carlos Augusto Gomes</name><affiliation><nlm:aff id="I17">Department of Surgery, Monte Sinai Hospital, Juiz de Fora, Brazil</nlm:aff></affiliation></author><author><name sortKey="Junior, Gerson Alves Pereira" sort="Junior, Gerson Alves Pereira" uniqKey="Junior G" first="Gerson Alves Pereira" last="Junior">Gerson Alves Pereira Junior</name><affiliation><nlm:aff id="I18">Emergency Unit, Department of Surgery, Ribeirão Preto, Brazil</nlm:aff></affiliation></author><author><name sortKey="Yuan, Kuo Ching" sort="Yuan, Kuo Ching" uniqKey="Yuan K" first="Kuo-Ching" last="Yuan">Kuo-Ching Yuan</name><affiliation><nlm:aff id="I19">Department of Surgery, Chang Gung Memorial Hospital, Taoyuan, Taiwan</nlm:aff></affiliation></author><author><name sortKey="Bala, Miklosh" sort="Bala, Miklosh" uniqKey="Bala M" first="Miklosh" last="Bala">Miklosh Bala</name><affiliation><nlm:aff id="I20">Department of General Surgery, Hadassah Medical Center, Jerusalem, Israel</nlm:aff></affiliation></author><author><name sortKey="Peev, Miroslav P" sort="Peev, Miroslav P" uniqKey="Peev M" first="Miroslav P" last="Peev">Miroslav P. Peev</name><affiliation><nlm:aff id="I6">Harvard Medical School, Division of Trauma, Emergency Surgery and Surgical Critical Care Massachusetts General Hospital, Boston, MA, USA</nlm:aff></affiliation></author><author><name sortKey="Cui, Yunfeng" sort="Cui, Yunfeng" uniqKey="Cui Y" first="Yunfeng" last="Cui">Yunfeng Cui</name><affiliation><nlm:aff id="I21">Department of Surgery, Tianjin Nankai Hospital, Nankai Clinical School of Medicine, Tianjin Medical University, Tianjin, China</nlm:aff></affiliation></author><author><name sortKey="Marwah, Sanjay" sort="Marwah, Sanjay" uniqKey="Marwah S" first="Sanjay" last="Marwah">Sanjay Marwah</name><affiliation><nlm:aff id="I22">Department of Surgery, Pt BDS Post-graduate Institute of Medical Sciences, Rohtak, India</nlm:aff></affiliation></author><author><name sortKey="Zachariah, Sanoop" sort="Zachariah, Sanoop" uniqKey="Zachariah S" first="Sanoop" last="Zachariah">Sanoop Zachariah</name><affiliation><nlm:aff id="I23">Department of Surgery, MOSC medical college, Cochin, India</nlm:aff></affiliation></author><author><name sortKey="Sakakushev, Boris" sort="Sakakushev, Boris" uniqKey="Sakakushev B" first="Boris" last="Sakakushev">Boris Sakakushev</name><affiliation><nlm:aff id="I24">First Clinic of General Surgery, University Hospital /UMBAL/ St George Plovdiv, Plovdiv, Bulgaria</nlm:aff></affiliation><affiliation><nlm:aff id="I25">General Surgery Clinic, Medical University/University Hospital St.George, Plovdiv, Bulgaria</nlm:aff></affiliation></author><author><name sortKey="Kong, Victor" sort="Kong, Victor" uniqKey="Kong V" first="Victor" last="Kong">Victor Kong</name><affiliation><nlm:aff id="I26">Department of Surgery, Edendale Hospital, Pietermaritzburg, Republic of South Africa</nlm:aff></affiliation></author><author><name sortKey="Ahmed, Adamu" sort="Ahmed, Adamu" uniqKey="Ahmed A" first="Adamu" last="Ahmed">Adamu Ahmed</name><affiliation><nlm:aff id="I27">Department of Surgery, Ahmadu Bello University Teaching Hospital Zaria, Kaduna, Nigeria</nlm:aff></affiliation></author><author><name sortKey="Abbas, Ashraf" sort="Abbas, Ashraf" uniqKey="Abbas A" first="Ashraf" last="Abbas">Ashraf Abbas</name><affiliation><nlm:aff id="I28">Department of Surgery, Mansoura University Hospital, Mansoura, Egypt</nlm:aff></affiliation></author><author><name sortKey="Gonsaga, Ricardo Alessandro Teixeira" sort="Gonsaga, Ricardo Alessandro Teixeira" uniqKey="Gonsaga R" first="Ricardo Alessandro Teixeira" last="Gonsaga">Ricardo Alessandro Teixeira Gonsaga</name><affiliation><nlm:aff id="I29">Department of Surgery, Faculdades Integradas Padre Albino, Catanduva, Brazil</nlm:aff></affiliation></author><author><name sortKey="Guercioni, Gianluca" sort="Guercioni, Gianluca" uniqKey="Guercioni G" first="Gianluca" last="Guercioni">Gianluca Guercioni</name><affiliation><nlm:aff id="I30">Department of Surgery, Mazzoni Hospital, Ascoli Piceno, Italy</nlm:aff></affiliation></author><author><name sortKey="Vettoretto, Nereo" sort="Vettoretto, Nereo" uniqKey="Vettoretto N" first="Nereo" last="Vettoretto">Nereo Vettoretto</name><affiliation><nlm:aff id="I31">Department of Surgery, Mellini Hospital, Chiari (BS), Italy</nlm:aff></affiliation></author><author><name sortKey="Poiasina, Elia" sort="Poiasina, Elia" uniqKey="Poiasina E" first="Elia" last="Poiasina">Elia Poiasina</name><affiliation><nlm:aff id="I3">Department of General Surgery, Ospedali Riuniti, Bergamo, Italy</nlm:aff></affiliation></author><author><name sortKey="Ben Ishay, Offir" sort="Ben Ishay, Offir" uniqKey="Ben Ishay O" first="Offir" last="Ben-Ishay">Offir Ben-Ishay</name><affiliation><nlm:aff id="I12">Department of General Surgery, Rambam Health Care Campus, Haifa, Israel</nlm:aff></affiliation></author><author><name sortKey="Diaz Nieto, Rafael" sort="Diaz Nieto, Rafael" uniqKey="Diaz Nieto R" first="Rafael" last="Díaz-Nieto">Rafael Díaz-Nieto</name><affiliation><nlm:aff id="I32">Department of General and Digestive Surgery, Virgen de la Victoria, University Hospital, Malaga, Spain</nlm:aff></affiliation></author><author><name sortKey="Massalou, Damien" sort="Massalou, Damien" uniqKey="Massalou D" first="Damien" last="Massalou">Damien Massalou</name><affiliation><nlm:aff id="I33">Department of General Surgery and Surgical Oncology, Université de Nice Sophia-Antipolis, Universitary Hospital of Nice, Nice, France</nlm:aff></affiliation></author><author><name sortKey="Skrovina, Matej" sort="Skrovina, Matej" uniqKey="Skrovina M" first="Matej" last="Skrovina">Matej Skrovina</name><affiliation><nlm:aff id="I34">Department of Surgery, Hospital and Oncological Centre, Novy Jicin, Czech Republic</nlm:aff></affiliation></author><author><name sortKey="Gerych, Ihor" sort="Gerych, Ihor" uniqKey="Gerych I" first="Ihor" last="Gerych">Ihor Gerych</name><affiliation><nlm:aff id="I35">Department of General Surgery, Lviv Emergency Hospital, Lviv, Ukraine</nlm:aff></affiliation></author><author><name sortKey="Augustin, Goran" sort="Augustin, Goran" uniqKey="Augustin G" first="Goran" last="Augustin">Goran Augustin</name><affiliation><nlm:aff id="I36">Department of Surgery, University Hospital Center Zagreb, Zagreb, Croatia</nlm:aff></affiliation></author><author><name sortKey="Kenig, Jakub" sort="Kenig, Jakub" uniqKey="Kenig J" first="Jakub" last="Kenig">Jakub Kenig</name><affiliation><nlm:aff id="I37">3rd Department of General Surger Jagiellonian Univeristy, Narutowicz Hospital, Krakow, Poland</nlm:aff></affiliation></author><author><name sortKey="Khokha, Vladimir" sort="Khokha, Vladimir" uniqKey="Khokha V" first="Vladimir" last="Khokha">Vladimir Khokha</name><affiliation><nlm:aff id="I38">Department of Surgery, Mozyr City Hospital, Mozyr, Belarus</nlm:aff></affiliation></author><author><name sortKey="Trana, Cristian" sort="Trana, Cristian" uniqKey="Trana C" first="Cristian" last="Tranà">Cristian Tranà</name><affiliation><nlm:aff id="I39">Department of Surgery, Ancona University, Ancona, Italy</nlm:aff></affiliation></author><author><name sortKey="Kok, Kenneth Yuh Yen" sort="Kok, Kenneth Yuh Yen" uniqKey="Kok K" first="Kenneth Yuh Yen" last="Kok">Kenneth Yuh Yen Kok</name><affiliation><nlm:aff id="I40">Department of Surgery, Ripas Hospital, Bandar Seri Begawan, Brunei</nlm:aff></affiliation></author><author><name sortKey="Mefire, Alain Chichom" sort="Mefire, Alain Chichom" uniqKey="Mefire A" first="Alain Chichom" last="Mefire">Alain Chichom Mefire</name><affiliation><nlm:aff id="I41">Clinical Sciences, Regional Hospitals Limbe and Buea, Limbe, Cameroon</nlm:aff></affiliation></author><author><name sortKey="Lee, Jae Gil" sort="Lee, Jae Gil" uniqKey="Lee J" first="Jae Gil" last="Lee">Jae Gil Lee</name><affiliation><nlm:aff id="I42">Department of Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea</nlm:aff></affiliation></author><author><name sortKey="Hong, Suk Kyung" sort="Hong, Suk Kyung" uniqKey="Hong S" first="Suk-Kyung" last="Hong">Suk-Kyung Hong</name><affiliation><nlm:aff id="I43">Division of Trauma and Surgical Critical Care, Department of Surgery, University of Ulsan, Seoul, Republic of Korea</nlm:aff></affiliation></author><author><name sortKey="Lohse, Helmut Alfredo Segovia" sort="Lohse, Helmut Alfredo Segovia" uniqKey="Lohse H" first="Helmut Alfredo Segovia" last="Lohse">Helmut Alfredo Segovia Lohse</name><affiliation><nlm:aff id="I44">II Cátedra de Clínica Quirúrgica, Hospital de Clínicas, Asuncion, Paraguay</nlm:aff></affiliation></author><author><name sortKey="Ghnnam, Wagih" sort="Ghnnam, Wagih" uniqKey="Ghnnam W" first="Wagih" last="Ghnnam">Wagih Ghnnam</name><affiliation><nlm:aff id="I45">Department of Surgery, Khamis Mushayt General Hospital, Khamis Mushayt, Saudi Arabia</nlm:aff></affiliation></author><author><name sortKey="Verni, Alfredo" sort="Verni, Alfredo" uniqKey="Verni A" first="Alfredo" last="Verni">Alfredo Verni</name><affiliation><nlm:aff id="I46">Department of Surgery, Cutral Co Clinic, Neuquen, Argentina</nlm:aff></affiliation></author><author><name sortKey="Lohsiriwat, Varut" sort="Lohsiriwat, Varut" uniqKey="Lohsiriwat V" first="Varut" last="Lohsiriwat">Varut Lohsiriwat</name><affiliation><nlm:aff id="I47">Department of Surgery, Faculty of Medicine Siriraj Hospital, Bangkok, Thailand</nlm:aff></affiliation></author><author><name sortKey="Siribumrungwong, Boonying" sort="Siribumrungwong, Boonying" uniqKey="Siribumrungwong B" first="Boonying" last="Siribumrungwong">Boonying Siribumrungwong</name><affiliation><nlm:aff id="I48">Department of Surgery, Thammasat University Hospital, Pathumthani, Thailand</nlm:aff></affiliation></author><author><name sortKey="Tavares, Alberto" sort="Tavares, Alberto" uniqKey="Tavares A" first="Alberto" last="Tavares">Alberto Tavares</name><affiliation><nlm:aff id="I49">Department of Surgery, Hospital Regional de Alta Especialidad del Bajio, Leon, Mexico</nlm:aff></affiliation></author><author><name sortKey="Baiocchi, Gianluca" sort="Baiocchi, Gianluca" uniqKey="Baiocchi G" first="Gianluca" last="Baiocchi">Gianluca Baiocchi</name><affiliation><nlm:aff id="I50">Department of Clinical and Experimental Sciences, Brescia University, Brescia, Italy</nlm:aff></affiliation></author><author><name sortKey="Das, Koray" sort="Das, Koray" uniqKey="Das K" first="Koray" last="Das">Koray Das</name><affiliation><nlm:aff id="I51">General Surgery, Adana Numune Training and Research Hospital, Adana, Turkey</nlm:aff></affiliation></author><author><name sortKey="Jarry, Julien" sort="Jarry, Julien" uniqKey="Jarry J" first="Julien" last="Jarry">Julien Jarry</name><affiliation><nlm:aff id="I52">Visceral Surgery, Military Hospital Desgenettes, Lyon, France</nlm:aff></affiliation></author><author><name sortKey="Zida, Maurice" sort="Zida, Maurice" uniqKey="Zida M" first="Maurice" last="Zida">Maurice Zida</name><affiliation><nlm:aff id="I53">Visceral Surgery, Teaching Hospital Yalgado Ouedraogo, Ouagadougou, Burkina Faso</nlm:aff></affiliation></author><author><name sortKey="Sato, Norio" sort="Sato, Norio" uniqKey="Sato N" first="Norio" last="Sato">Norio Sato</name><affiliation><nlm:aff id="I8">Department of Primary Care & Emergency Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan</nlm:aff></affiliation></author><author><name sortKey="Murata, Kiyoshi" sort="Murata, Kiyoshi" uniqKey="Murata K" first="Kiyoshi" last="Murata">Kiyoshi Murata</name><affiliation><nlm:aff id="I54">Department of Acute and Critical care medicine, Tokyo Medical and Dental University, Tokyo, Japan</nlm:aff></affiliation></author><author><name sortKey="Shoko, Tomohisa" sort="Shoko, Tomohisa" uniqKey="Shoko T" first="Tomohisa" last="Shoko">Tomohisa Shoko</name><affiliation><nlm:aff id="I55">The Shock Trauma and Emergency Medical Center, Matsudo City Hospital, Chiba, Japan</nlm:aff></affiliation></author><author><name sortKey="Irahara, Takayuki" sort="Irahara, Takayuki" uniqKey="Irahara T" first="Takayuki" last="Irahara">Takayuki Irahara</name><affiliation><nlm:aff id="I56">Emergency and Critical Care Center of Nippon Medical School, Tama-Nagayama Hospital, Tokyo, Japan</nlm:aff></affiliation></author><author><name sortKey="Hamedelneel, Ahmed O" sort="Hamedelneel, Ahmed O" uniqKey="Hamedelneel A" first="Ahmed O" last="Hamedelneel">Ahmed O. Hamedelneel</name><affiliation><nlm:aff id="I57">Department of Surgery, Our Lady of Lourdes Hospital, Drogheda, Ireland</nlm:aff></affiliation></author><author><name sortKey="Naidoo, Noel" sort="Naidoo, Noel" uniqKey="Naidoo N" first="Noel" last="Naidoo">Noel Naidoo</name><affiliation><nlm:aff id="I58">Department of Surgery, Port Shepstone Hospital, Port Shepstone, South Africa</nlm:aff></affiliation></author><author><name sortKey="Adesunkanmi, Abdul Rashid Kayode" sort="Adesunkanmi, Abdul Rashid Kayode" uniqKey="Adesunkanmi A" first="Abdul Rashid Kayode" last="Adesunkanmi">Abdul Rashid Kayode Adesunkanmi</name><affiliation><nlm:aff id="I59">Department of Surgery, College of Health Sciences, Obafemi Awolowo University Hospital, Ile-Ife, Nigeria</nlm:aff></affiliation></author><author><name sortKey="Kobe, Yoshiro" sort="Kobe, Yoshiro" uniqKey="Kobe Y" first="Yoshiro" last="Kobe">Yoshiro Kobe</name><affiliation><nlm:aff id="I60">Department of Emergency and Critical Care Medicine, Chiba University Hospital, Chiba, Japan</nlm:aff></affiliation></author><author><name sortKey="Attri, Ak" sort="Attri, Ak" uniqKey="Attri A" first="Ak" last="Attri">Ak Attri</name><affiliation><nlm:aff id="I11">Department of Surgery, Govt Medical College and Hospital, Chandigarh, India</nlm:aff></affiliation></author><author><name sortKey="Sharma, Rajeev" sort="Sharma, Rajeev" uniqKey="Sharma R" first="Rajeev" last="Sharma">Rajeev Sharma</name><affiliation><nlm:aff id="I11">Department of Surgery, Govt Medical College and Hospital, Chandigarh, India</nlm:aff></affiliation></author><author><name sortKey="Coccolini, Federico" sort="Coccolini, Federico" uniqKey="Coccolini F" first="Federico" last="Coccolini">Federico Coccolini</name><affiliation><nlm:aff id="I3">Department of General Surgery, Ospedali Riuniti, Bergamo, Italy</nlm:aff></affiliation></author><author><name sortKey="El Zalabany, Tamer" sort="El Zalabany, Tamer" uniqKey="El Zalabany T" first="Tamer" last="El Zalabany">Tamer El Zalabany</name><affiliation><nlm:aff id="I61">Department of Surgery, Bahrain Defence Force Hospital, Manama, Bahrain</nlm:aff></affiliation></author><author><name sortKey="Khalifa, Khalid Al" sort="Khalifa, Khalid Al" uniqKey="Khalifa K" first="Khalid Al" last="Khalifa">Khalid Al Khalifa</name><affiliation><nlm:aff id="I61">Department of Surgery, Bahrain Defence Force Hospital, Manama, Bahrain</nlm:aff></affiliation></author><author><name sortKey="Sanjuan, Juan" sort="Sanjuan, Juan" uniqKey="Sanjuan J" first="Juan" last="Sanjuan">Juan Sanjuan</name><affiliation><nlm:aff id="I16">Department of Surgery, Universidad del Valle, Fundacion Valle del Lili, Cali, Colombia</nlm:aff></affiliation></author><author><name sortKey="Barnabe, Rita" sort="Barnabe, Rita" uniqKey="Barnabe R" first="Rita" last="Barnabé">Rita Barnabé</name><affiliation><nlm:aff id="I15">Department of Surgery, Maggiore Hospital, Bologna, Italy</nlm:aff></affiliation></author><author><name sortKey="Ishii, Wataru" sort="Ishii, Wataru" uniqKey="Ishii W" first="Wataru" last="Ishii">Wataru Ishii</name><affiliation><nlm:aff id="I62">Department of Emergency Medicine, Kyoto Second Red Cross Hospital, Kyoto, Japan</nlm:aff></affiliation></author></analytic><series><title level="j">World Journal of Emergency Surgery : WJES</title><idno type="eISSN">1749-7922</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Despite advances in diagnosis, surgery, and antimicrobial therapy, mortality rates associated with complicated intra-abdominal infections remain exceedingly high. The World Society of Emergency Surgery (WSES) has designed the CIAOW study in order to describe the clinical, microbiological, and management-related profiles of both community- and healthcare-acquired complicated intra-abdominal infections in a worldwide context. The CIAOW study (Complicated Intra-Abdominal infection Observational Worldwide Study) is a multicenter observational study currently underway in 57 medical institutions worldwide. The study includes patients undergoing surgery or interventional drainage to address complicated intra-abdominal infections. This preliminary report includes all data from almost the first two months of the six-month study period. Patients who met inclusion criteria with either community-acquired or healthcare-associated complicated intra-abdominal infections (IAIs) were included in the study. 702 patients with a mean age of 49.2 years (range 18–98) were enrolled in the study. 272 patients (38.7%) were women and 430 (62.3%) were men. Among these patients, 615 (87.6%) were affected by community-acquired IAIs while the remaining 87 (12.4%) suffered from healthcare-associated infections. Generalized peritonitis was observed in 304 patients (43.3%), whereas localized peritonitis or abscesses was registered in 398 (57.7%) patients.</p><p>The overall mortality rate was 10.1% (71/702). The final results of the CIAOW Study will be published following the conclusion of the study period in March 2013.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Sartelli, M" uniqKey="Sartelli M">M Sartelli</name></author><author><name sortKey="Viale, P" uniqKey="Viale P">P Viale</name></author><author><name sortKey="Koike, K" uniqKey="Koike K">K Koike</name></author><author><name sortKey="Pea, F" uniqKey="Pea F">F Pea</name></author><author><name sortKey="Tumietto, F" uniqKey="Tumietto F">F Tumietto</name></author><author><name sortKey="Van Goor, H" uniqKey="Van Goor H">H van Goor</name></author><author><name sortKey="Guercioni, G" uniqKey="Guercioni G">G Guercioni</name></author><author><name sortKey="Nespoli, A" uniqKey="Nespoli A">A Nespoli</name></author><author><name sortKey="Trana, C" uniqKey="Trana C">C Tranà</name></author><author><name sortKey="Catena, F" uniqKey="Catena F">F Catena</name></author><author><name sortKey="Ansaloni, L" uniqKey="Ansaloni L">L Ansaloni</name></author><author><name sortKey="Leppaniemi, A" uniqKey="Leppaniemi A">A Leppaniemi</name></author><author><name sortKey="Biffl, W" uniqKey="Biffl W">W Biffl</name></author><author><name sortKey="Moore, Fa" uniqKey="Moore F">FA Moore</name></author><author><name sortKey="Poggetti, R" uniqKey="Poggetti R">R Poggetti</name></author><author><name sortKey="Pinna, Ad" uniqKey="Pinna A">AD Pinna</name></author><author><name sortKey="Moore, Ee" uniqKey="Moore E">EE Moore</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sartelli, M" uniqKey="Sartelli M">M Sartelli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Azzarello, G" uniqKey="Azzarello G">G Azzarello</name></author><author><name sortKey="Lanteri, R" uniqKey="Lanteri R">R Lanteri</name></author><author><name sortKey="Rapisarda, C" uniqKey="Rapisarda C">C Rapisarda</name></author><author><name sortKey="Santangelo, M" uniqKey="Santangelo M">M Santangelo</name></author><author><name sortKey="Racalbuto, A" uniqKey="Racalbuto A">A Racalbuto</name></author><author><name sortKey="Minutolo, V" uniqKey="Minutolo V">V Minutolo</name></author><author><name sortKey="Di Cataldo, A" uniqKey="Di Cataldo A">A Di Cataldo</name></author><author><name sortKey="Licata, A" uniqKey="Licata A">A Licata</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gazelle, Gs" uniqKey="Gazelle G">GS Gazelle</name></author><author><name sortKey="Mueller, Pr" uniqKey="Mueller P">PR Mueller</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vansonnenberg, E" uniqKey="Vansonnenberg E">E VanSonnenberg</name></author><author><name sortKey="Ferrucci, Jt" uniqKey="Ferrucci J">JT Ferrucci</name></author><author><name sortKey="Mueller, Pr" uniqKey="Mueller P">PR Mueller</name></author><author><name sortKey="Wittenberg, J" uniqKey="Wittenberg J">J Wittenberg</name></author><author><name sortKey="Simeone, Jf" uniqKey="Simeone J">JF Simeone</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bouali, K" uniqKey="Bouali K">K Bouali</name></author><author><name sortKey="Magotteaux, P" uniqKey="Magotteaux P">P Magotteaux</name></author><author><name sortKey="Jadot, A" uniqKey="Jadot A">A Jadot</name></author><author><name sortKey="Saive, C" uniqKey="Saive C">C Saive</name></author><author><name sortKey="Lombard, R" uniqKey="Lombard R">R Lombard</name></author><author><name sortKey="Weerts, J" uniqKey="Weerts J">J Weerts</name></author><author><name sortKey="Dallemagne, B" uniqKey="Dallemagne B">B Dallemagne</name></author><author><name sortKey="Jehaes, C" uniqKey="Jehaes C">C Jehaes</name></author><author><name sortKey="Delforge, M" uniqKey="Delforge M">M Delforge</name></author><author><name sortKey="Fontaine, F" uniqKey="Fontaine F">F Fontaine</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vansonnenberg, E" uniqKey="Vansonnenberg E">E VanSonnenberg</name></author><author><name sortKey="Wing, Vw" uniqKey="Wing V">VW Wing</name></author><author><name sortKey="Casola, G" uniqKey="Casola G">G Casola</name></author><author><name sortKey="Coons, Hg" uniqKey="Coons H">HG Coons</name></author><author><name sortKey="Nakamoto, Sk" uniqKey="Nakamoto S">SK Nakamoto</name></author><author><name sortKey="Mueller, Pr" uniqKey="Mueller P">PR Mueller</name></author><author><name sortKey="Ferrucci, Jt" uniqKey="Ferrucci J">JT Ferrucci</name></author><author><name sortKey="Halasz, Na" uniqKey="Halasz N">NA Halasz</name></author><author><name sortKey="Simeone, Jf" uniqKey="Simeone J">JF Simeone</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bufalari, A" uniqKey="Bufalari A">A Bufalari</name></author><author><name sortKey="Giustozzi, G" uniqKey="Giustozzi G">G Giustozzi</name></author><author><name sortKey="Moggi, L" uniqKey="Moggi L">L Moggi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vansonnenberg, E" uniqKey="Vansonnenberg E">E VanSonnenberg</name></author><author><name sortKey="Mueller, Pr" uniqKey="Mueller P">PR Mueller</name></author><author><name sortKey="Ferrucci, Jt" uniqKey="Ferrucci J">JT Ferrucci</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jaffe, Ta" uniqKey="Jaffe T">TA Jaffe</name></author><author><name sortKey="Nelson, Rc" uniqKey="Nelson R">RC Nelson</name></author><author><name sortKey="Delong, D" uniqKey="Delong D">D DeLong</name></author><author><name sortKey="Paulson, Ek" uniqKey="Paulson E">EK Paulson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Ruler, O" uniqKey="Van Ruler O">O van Ruler</name></author><author><name sortKey="Lamme, B" uniqKey="Lamme B">B Lamme</name></author><author><name sortKey="Gouma, Dj" uniqKey="Gouma D">DJ Gouma</name></author><author><name sortKey="Reitsma, Jb" uniqKey="Reitsma J">JB Reitsma</name></author><author><name sortKey="Boermeester, Ma" uniqKey="Boermeester M">MA Boermeester</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hutchins, Rr" uniqKey="Hutchins R">RR Hutchins</name></author><author><name sortKey="Gunning, Mp" uniqKey="Gunning M">MP Gunning</name></author><author><name sortKey="Lucas, Dn" uniqKey="Lucas D">DN Lucas</name></author><author><name sortKey="Allen Mersh, Tg" uniqKey="Allen Mersh T">TG Allen-Mersh</name></author><author><name sortKey="Soni, Nc" uniqKey="Soni N">NC Soni</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lamme, B" uniqKey="Lamme B">B Lamme</name></author><author><name sortKey="Mahler, Cw" uniqKey="Mahler C">CW Mahler</name></author><author><name sortKey="Van Ruler, O" uniqKey="Van Ruler O">O van Ruler</name></author><author><name sortKey="Gouma, Dj" uniqKey="Gouma D">DJ Gouma</name></author><author><name sortKey="Reitsma, Jb" uniqKey="Reitsma J">JB Reitsma</name></author><author><name sortKey="Boermeester, Ma" uniqKey="Boermeester M">MA Boermeester</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hawser, Sp" uniqKey="Hawser S">SP Hawser</name></author><author><name sortKey="Bouchillon, Sk" uniqKey="Bouchillon S">SK Bouchillon</name></author><author><name sortKey="Lascols, C" uniqKey="Lascols C">C Lascols</name></author><author><name sortKey="Hackel, M" uniqKey="Hackel M">M Hackel</name></author><author><name sortKey="Hoban, Dj" uniqKey="Hoban D">DJ Hoban</name></author><author><name sortKey="Badal, Re" uniqKey="Badal R">RE Badal</name></author><author><name sortKey="Woodford, N" uniqKey="Woodford N">N Woodford</name></author><author><name sortKey="Livermore, Dm" uniqKey="Livermore D">DM Livermore</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sartelli, M" uniqKey="Sartelli M">M Sartelli</name></author><author><name sortKey="Catena, F" uniqKey="Catena F">F Catena</name></author><author><name sortKey="Ansaloni, L" uniqKey="Ansaloni L">L Ansaloni</name></author><author><name sortKey="Leppaniemi, A" uniqKey="Leppaniemi A">A Leppaniemi</name></author><author><name sortKey="Taviloglu, K" uniqKey="Taviloglu K">K Taviloglu</name></author><author><name sortKey="Goor, H" uniqKey="Goor H">H Goor</name></author><author><name sortKey="Viale, P" uniqKey="Viale P">P Viale</name></author><author><name sortKey="Lazzareschi, Dv" uniqKey="Lazzareschi D">DV Lazzareschi</name></author><author><name sortKey="Coccolini, F" uniqKey="Coccolini F">F Coccolini</name></author><author><name sortKey="Corbella, D" uniqKey="Corbella D">D Corbella</name></author><author><name sortKey="Werra, C" uniqKey="Werra C">C Werra</name></author><author><name sortKey="Marrelli, D" uniqKey="Marrelli D">D Marrelli</name></author><author><name sortKey="Colizza, S" uniqKey="Colizza S">S Colizza</name></author><author><name sortKey="Scibe, R" uniqKey="Scibe R">R Scibè</name></author><author><name sortKey="Alis, H" uniqKey="Alis H">H Alis</name></author><author><name sortKey="Torer, N" uniqKey="Torer N">N Torer</name></author><author><name sortKey="Navarro, S" uniqKey="Navarro S">S Navarro</name></author><author><name sortKey="Sakakushev, B" uniqKey="Sakakushev B">B Sakakushev</name></author><author><name sortKey="Massalou, D" uniqKey="Massalou D">D Massalou</name></author><author><name sortKey="Augustin, G" uniqKey="Augustin G">G Augustin</name></author><author><name sortKey="Catani, M" uniqKey="Catani M">M Catani</name></author><author><name sortKey="Kauhanen, S" uniqKey="Kauhanen S">S Kauhanen</name></author><author><name sortKey="Pletinckx, P" uniqKey="Pletinckx P">P Pletinckx</name></author><author><name sortKey="Kenig, J" uniqKey="Kenig J">J Kenig</name></author><author><name sortKey="Saverio, S" uniqKey="Saverio S">S Saverio</name></author><author><name sortKey="Jovine, E" uniqKey="Jovine E">E Jovine</name></author><author><name sortKey="Guercioni, G" uniqKey="Guercioni G">G Guercioni</name></author><author><name sortKey="Skrovina, M" uniqKey="Skrovina M">M Skrovina</name></author><author><name sortKey="Diaz Nieto, R" uniqKey="Diaz Nieto R">R Diaz-Nieto</name></author><author><name sortKey="Ferrero, A" uniqKey="Ferrero A">A Ferrero</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="review-article" xml:lang="en"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">World J Emerg Surg</journal-id><journal-id journal-id-type="iso-abbrev">World J Emerg Surg</journal-id><journal-title-group><journal-title>World Journal of Emergency Surgery : WJES</journal-title></journal-title-group><issn pub-type="epub">1749-7922</issn><publisher><publisher-name>BioMed Central</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">23286785</article-id><article-id pub-id-type="pmc">3538624</article-id><article-id pub-id-type="publisher-id">1749-7922-8-1</article-id><article-id pub-id-type="doi">10.1186/1749-7922-8-1</article-id><article-categories><subj-group subj-group-type="heading"><subject>Review</subject></subj-group></article-categories><title-group><article-title>Complicated intra-abdominal infections in a worldwide context: an observational prospective study (CIAOW Study)</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes" id="A1"><name><surname>Sartelli</surname><given-names>Massimo</given-names></name><xref ref-type="aff" rid="I1">1</xref><email>m.sartelli@virgilio.it</email></contrib><contrib contrib-type="author" id="A2"><name><surname>Catena</surname><given-names>Fausto</given-names></name><xref ref-type="aff" rid="I2">2</xref><email>faustocatena@gmail.com</email></contrib><contrib contrib-type="author" id="A3"><name><surname>Ansaloni</surname><given-names>Luca</given-names></name><xref ref-type="aff" rid="I3">3</xref><email>lansaloni@ospedaliriuniti.bergamo.it</email></contrib><contrib contrib-type="author" id="A4"><name><surname>Moore</surname><given-names>Ernest</given-names></name><xref ref-type="aff" rid="I4">4</xref><email>ernest.moore@dhha.org</email></contrib><contrib contrib-type="author" id="A5"><name><surname>Malangoni</surname><given-names>Mark</given-names></name><xref ref-type="aff" rid="I5">5</xref><email>mmalangoni@absurgery.org</email></contrib><contrib contrib-type="author" id="A6"><name><surname>Velmahos</surname><given-names>George</given-names></name><xref ref-type="aff" rid="I6">6</xref><email>GVELMAHOS@PARTNERS.ORG</email></contrib><contrib contrib-type="author" id="A7"><name><surname>Coimbra</surname><given-names>Raul</given-names></name><xref ref-type="aff" rid="I7">7</xref><email>rcoimbra@ucsd.edu</email></contrib><contrib contrib-type="author" id="A8"><name><surname>Koike</surname><given-names>Kaoru</given-names></name><xref ref-type="aff" rid="I8">8</xref><email>kkoike@kuhp.kyoto-u.ac.jp</email></contrib><contrib contrib-type="author" id="A9"><name><surname>Leppaniemi</surname><given-names>Ari</given-names></name><xref ref-type="aff" rid="I9">9</xref><email>Ari.Leppaniemi@hus.fi</email></contrib><contrib contrib-type="author" id="A10"><name><surname>Biffl</surname><given-names>Walter</given-names></name><xref ref-type="aff" rid="I4">4</xref><email>Walter.Biffl@dhha.org</email></contrib><contrib contrib-type="author" id="A11"><name><surname>Balogh</surname><given-names>Zsolt</given-names></name><xref ref-type="aff" rid="I10">10</xref><email>zsolt.balogh@hnehealth.nsw.gov.au</email></contrib><contrib contrib-type="author" id="A12"><name><surname>Bendinelli</surname><given-names>Cino</given-names></name><xref ref-type="aff" rid="I10">10</xref><email>Cino.Bendinelli@hnehealth.nsw.gov.au</email></contrib><contrib contrib-type="author" id="A13"><name><surname>Gupta</surname><given-names>Sanjay</given-names></name><xref ref-type="aff" rid="I11">11</xref><email>sandiv99@yahoo.co.uk</email></contrib><contrib contrib-type="author" id="A14"><name><surname>Kluger</surname><given-names>Yoram</given-names></name><xref ref-type="aff" rid="I12">12</xref><email>y_kluger@rambam.health.gov.il</email></contrib><contrib contrib-type="author" id="A15"><name><surname>Agresta</surname><given-names>Ferdinando</given-names></name><xref ref-type="aff" rid="I13">13</xref><email>fagresta@libero.it</email></contrib><contrib 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id="A55"><name><surname>Baiocchi</surname><given-names>Gianluca</given-names></name><xref ref-type="aff" rid="I50">50</xref><email>baiocchi@med.unibs.it</email></contrib><contrib contrib-type="author" id="A56"><name><surname>Das</surname><given-names>Koray</given-names></name><xref ref-type="aff" rid="I51">51</xref><email>koraydas@yahoo.com</email></contrib><contrib contrib-type="author" id="A57"><name><surname>Jarry</surname><given-names>Julien</given-names></name><xref ref-type="aff" rid="I52">52</xref><email>julienjarry@hotmail.com</email></contrib><contrib contrib-type="author" id="A58"><name><surname>Zida</surname><given-names>Maurice</given-names></name><xref ref-type="aff" rid="I53">53</xref><email>zimaur@yahoo.fr</email></contrib><contrib contrib-type="author" id="A59"><name><surname>Sato</surname><given-names>Norio</given-names></name><xref ref-type="aff" rid="I8">8</xref><email>drnori@kuhp.kyoto-u.ac.jp</email></contrib><contrib contrib-type="author" id="A60"><name><surname>Murata</surname><given-names>Kiyoshi</given-names></name><xref ref-type="aff" rid="I54">54</xref><email>murata.accm@tmd.ac.jp</email></contrib><contrib contrib-type="author" id="A61"><name><surname>Shoko</surname><given-names>Tomohisa</given-names></name><xref ref-type="aff" rid="I55">55</xref><email>shoukoaccm@me.com</email></contrib><contrib contrib-type="author" id="A62"><name><surname>Irahara</surname><given-names>Takayuki</given-names></name><xref ref-type="aff" rid="I56">56</xref><email>Iraira19@aol.com</email></contrib><contrib contrib-type="author" id="A63"><name><surname>Hamedelneel</surname><given-names>Ahmed O</given-names></name><xref ref-type="aff" rid="I57">57</xref><email>barcelonamst@hotmail.com</email></contrib><contrib contrib-type="author" id="A64"><name><surname>Naidoo</surname><given-names>Noel</given-names></name><xref ref-type="aff" rid="I58">58</xref><email>noel.naidoo@gmail.com</email></contrib><contrib contrib-type="author" id="A65"><name><surname>Adesunkanmi</surname><given-names>Abdul Rashid Kayode</given-names></name><xref ref-type="aff" rid="I59">59</xref><email>adesunkanmi@yahoo.com</email></contrib><contrib contrib-type="author" id="A66"><name><surname>Kobe</surname><given-names>Yoshiro</given-names></name><xref ref-type="aff" rid="I60">60</xref><email>y-kobe@umin.org</email></contrib><contrib contrib-type="author" id="A67"><name><surname>Attri</surname><given-names>AK</given-names></name><xref ref-type="aff" rid="I11">11</xref><email>sandiv99@yahoo.co.uk</email></contrib><contrib contrib-type="author" id="A68"><name><surname>Sharma</surname><given-names>Rajeev</given-names></name><xref ref-type="aff" rid="I11">11</xref><email>sandiv99@yahoo.co.uk</email></contrib><contrib contrib-type="author" id="A69"><name><surname>Coccolini</surname><given-names>Federico</given-names></name><xref ref-type="aff" rid="I3">3</xref><email>fedecocco@iol.it</email></contrib><contrib contrib-type="author" id="A70"><name><surname>El Zalabany</surname><given-names>Tamer</given-names></name><xref ref-type="aff" rid="I61">61</xref><email>dtzalabany@hotmail.com</email></contrib><contrib contrib-type="author" id="A71"><name><surname>Khalifa</surname><given-names>Khalid Al</given-names></name><xref ref-type="aff" rid="I61">61</xref><email>dtzalabany@hotmail.com</email></contrib><contrib contrib-type="author" id="A72"><name><surname>Sanjuan</surname><given-names>Juan</given-names></name><xref ref-type="aff" rid="I16">16</xref><email>ordonezcarlosa@gmail.com</email></contrib><contrib contrib-type="author" id="A73"><name><surname>Barnabé</surname><given-names>Rita</given-names></name><xref ref-type="aff" rid="I15">15</xref><email>barnaberita@libero.it</email></contrib><contrib contrib-type="author" id="A74"><name><surname>Ishii</surname><given-names>Wataru</given-names></name><xref ref-type="aff" rid="I62">62</xref><email>wataru84@coda.ocn.ne.jp</email></contrib></contrib-group><aff id="I1"><label>1</label>Department of Surgery, Macerata Hospital, Macerata, Italy</aff><aff id="I2"><label>2</label>Emergency Surgery, Maggiore Parma Hospital, Parma, Italy</aff><aff id="I3"><label>3</label>Department of General Surgery, Ospedali Riuniti, Bergamo, Italy</aff><aff id="I4"><label>4</label>Department of Surgery, Denver Health Medical Center, Denver, CO, USA</aff><aff id="I5"><label>5</label>American Board of Surgery, Philadelphia, PA, USA</aff><aff id="I6"><label>6</label>Harvard Medical School, Division of Trauma, Emergency Surgery and Surgical Critical Care Massachusetts General Hospital, Boston, MA, USA</aff><aff id="I7"><label>7</label>Department of Surgery, UC San Diego Health System, San Diego, CA, USA</aff><aff id="I8"><label>8</label>Department of Primary Care & Emergency Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan</aff><aff id="I9"><label>9</label>Department of Abdominal Surgery, University Hospital Meilahti, Helsinki, Finland</aff><aff id="I10"><label>10</label>Department of Surgery, University of Newcastle, Newcastle, NSW, Australia</aff><aff id="I11"><label>11</label>Department of Surgery, Govt Medical College and Hospital, Chandigarh, India</aff><aff id="I12"><label>12</label>Department of General Surgery, Rambam Health Care Campus, Haifa, Israel</aff><aff id="I13"><label>13</label>Department of Surgery, Adria Hospital, Adria, Italy</aff><aff id="I14"><label>14</label>Trauma Surgery Unit, Maggiore Hospital, Bologna, Italy</aff><aff id="I15"><label>15</label>Department of Surgery, Maggiore Hospital, Bologna, Italy</aff><aff id="I16"><label>16</label>Department of Surgery, Universidad del Valle, Fundacion Valle del Lili, Cali, Colombia</aff><aff id="I17"><label>17</label>Department of Surgery, Monte Sinai Hospital, Juiz de Fora, Brazil</aff><aff id="I18"><label>18</label>Emergency Unit, Department of Surgery, Ribeirão Preto, Brazil</aff><aff id="I19"><label>19</label>Department of Surgery, Chang Gung Memorial Hospital, Taoyuan, Taiwan</aff><aff id="I20"><label>20</label>Department of General Surgery, Hadassah Medical Center, Jerusalem, Israel</aff><aff id="I21"><label>21</label>Department of Surgery, Tianjin Nankai Hospital, Nankai Clinical School of Medicine, Tianjin Medical University, Tianjin, China</aff><aff id="I22"><label>22</label>Department of Surgery, Pt BDS Post-graduate Institute of Medical Sciences, Rohtak, India</aff><aff id="I23"><label>23</label>Department of Surgery, MOSC medical college, Cochin, India</aff><aff id="I24"><label>24</label>First Clinic of General Surgery, University Hospital /UMBAL/ St George Plovdiv, Plovdiv, Bulgaria</aff><aff id="I25"><label>25</label>General Surgery Clinic, Medical University/University Hospital St.George, Plovdiv, Bulgaria</aff><aff id="I26"><label>26</label>Department of Surgery, Edendale Hospital, Pietermaritzburg, Republic of South Africa</aff><aff id="I27"><label>27</label>Department of Surgery, Ahmadu Bello University Teaching Hospital Zaria, Kaduna, Nigeria</aff><aff id="I28"><label>28</label>Department of Surgery, Mansoura University Hospital, Mansoura, Egypt</aff><aff id="I29"><label>29</label>Department of Surgery, Faculdades Integradas Padre Albino, Catanduva, Brazil</aff><aff id="I30"><label>30</label>Department of Surgery, Mazzoni Hospital, Ascoli Piceno, Italy</aff><aff id="I31"><label>31</label>Department of Surgery, Mellini Hospital, Chiari (BS), Italy</aff><aff id="I32"><label>32</label>Department of General and Digestive Surgery, Virgen de la Victoria, University Hospital, Malaga, Spain</aff><aff id="I33"><label>33</label>Department of General Surgery and Surgical Oncology, Université de Nice Sophia-Antipolis, Universitary Hospital of Nice, Nice, France</aff><aff id="I34"><label>34</label>Department of Surgery, Hospital and Oncological Centre, Novy Jicin, Czech Republic</aff><aff id="I35"><label>35</label>Department of General Surgery, Lviv Emergency Hospital, Lviv, Ukraine</aff><aff id="I36"><label>36</label>Department of Surgery, University Hospital Center Zagreb, Zagreb, Croatia</aff><aff id="I37"><label>37</label>3rd Department of General Surger Jagiellonian Univeristy, Narutowicz Hospital, Krakow, Poland</aff><aff id="I38"><label>38</label>Department of Surgery, Mozyr City Hospital, Mozyr, Belarus</aff><aff id="I39"><label>39</label>Department of Surgery, Ancona University, Ancona, Italy</aff><aff id="I40"><label>40</label>Department of Surgery, Ripas Hospital, Bandar Seri Begawan, Brunei</aff><aff id="I41"><label>41</label>Clinical Sciences, Regional Hospitals Limbe and Buea, Limbe, Cameroon</aff><aff id="I42"><label>42</label>Department of Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea</aff><aff id="I43"><label>43</label>Division of Trauma and Surgical Critical Care, Department of Surgery, University of Ulsan, Seoul, Republic of Korea</aff><aff id="I44"><label>44</label>II Cátedra de Clínica Quirúrgica, Hospital de Clínicas, Asuncion, Paraguay</aff><aff id="I45"><label>45</label>Department of Surgery, Khamis Mushayt General Hospital, Khamis Mushayt, Saudi Arabia</aff><aff id="I46"><label>46</label>Department of Surgery, Cutral Co Clinic, Neuquen, Argentina</aff><aff id="I47"><label>47</label>Department of Surgery, Faculty of Medicine Siriraj Hospital, Bangkok, Thailand</aff><aff id="I48"><label>48</label>Department of Surgery, Thammasat University Hospital, Pathumthani, Thailand</aff><aff id="I49"><label>49</label>Department of Surgery, Hospital Regional de Alta Especialidad del Bajio, Leon, Mexico</aff><aff id="I50"><label>50</label>Department of Clinical and Experimental Sciences, Brescia University, Brescia, Italy</aff><aff id="I51"><label>51</label>General Surgery, Adana Numune Training and Research Hospital, Adana, Turkey</aff><aff id="I52"><label>52</label>Visceral Surgery, Military Hospital Desgenettes, Lyon, France</aff><aff id="I53"><label>53</label>Visceral Surgery, Teaching Hospital Yalgado Ouedraogo, Ouagadougou, Burkina Faso</aff><aff id="I54"><label>54</label>Department of Acute and Critical care medicine, Tokyo Medical and Dental University, Tokyo, Japan</aff><aff id="I55"><label>55</label>The Shock Trauma and Emergency Medical Center, Matsudo City Hospital, Chiba, Japan</aff><aff id="I56"><label>56</label>Emergency and Critical Care Center of Nippon Medical School, Tama-Nagayama Hospital, Tokyo, Japan</aff><aff id="I57"><label>57</label>Department of Surgery, Our Lady of Lourdes Hospital, Drogheda, Ireland</aff><aff id="I58"><label>58</label>Department of Surgery, Port Shepstone Hospital, Port Shepstone, South Africa</aff><aff id="I59"><label>59</label>Department of Surgery, College of Health Sciences, Obafemi Awolowo University Hospital, Ile-Ife, Nigeria</aff><aff id="I60"><label>60</label>Department of Emergency and Critical Care Medicine, Chiba University Hospital, Chiba, Japan</aff><aff id="I61"><label>61</label>Department of Surgery, Bahrain Defence Force Hospital, Manama, Bahrain</aff><aff id="I62"><label>62</label>Department of Emergency Medicine, Kyoto Second Red Cross Hospital, Kyoto, Japan</aff><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>3</day><month>1</month><year>2013</year></pub-date><volume>8</volume><fpage>1</fpage><lpage>1</lpage><history><date date-type="received"><day>28</day><month>12</month><year>2012</year></date><date date-type="accepted"><day>2</day><month>1</month><year>2013</year></date></history><permissions><copyright-statement>Copyright ©2013 Sartelli et al; licensee BioMed Central Ltd.</copyright-statement><copyright-year>2013</copyright-year><copyright-holder>Sartelli et al; licensee BioMed Central Ltd.</copyright-holder><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/2.0"><license-p>This is an Open Access article distributed under the terms of the Creative Commons Attribution License (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/2.0">http://creativecommons.org/licenses/by/2.0</ext-link>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p></license></permissions><self-uri xlink:href="http://www.wjes.org/content/8/1/1"></self-uri><abstract><p>Despite advances in diagnosis, surgery, and antimicrobial therapy, mortality rates associated with complicated intra-abdominal infections remain exceedingly high. The World Society of Emergency Surgery (WSES) has designed the CIAOW study in order to describe the clinical, microbiological, and management-related profiles of both community- and healthcare-acquired complicated intra-abdominal infections in a worldwide context. The CIAOW study (Complicated Intra-Abdominal infection Observational Worldwide Study) is a multicenter observational study currently underway in 57 medical institutions worldwide. The study includes patients undergoing surgery or interventional drainage to address complicated intra-abdominal infections. This preliminary report includes all data from almost the first two months of the six-month study period. Patients who met inclusion criteria with either community-acquired or healthcare-associated complicated intra-abdominal infections (IAIs) were included in the study. 702 patients with a mean age of 49.2 years (range 18–98) were enrolled in the study. 272 patients (38.7%) were women and 430 (62.3%) were men. Among these patients, 615 (87.6%) were affected by community-acquired IAIs while the remaining 87 (12.4%) suffered from healthcare-associated infections. Generalized peritonitis was observed in 304 patients (43.3%), whereas localized peritonitis or abscesses was registered in 398 (57.7%) patients.</p><p>The overall mortality rate was 10.1% (71/702). The final results of the CIAOW Study will be published following the conclusion of the study period in March 2013.</p></abstract></article-meta></front><body><sec><title>Introduction</title><p>Intra-abdominal infections (IAIs) include a wide spectrum of pathological conditions, ranging from uncomplicated appendicitis to fecal peritonitis [<xref ref-type="bibr" rid="B1">1</xref>].</p><p>From a clinical perspective, IAIs are classified in two major categories: complicated and uncomplicated.</p><p>In uncomplicated IAIs, the infectious process only involves a single organ and does not spread to the peritoneum. Patients with such infections can be managed with either surgical resection or antibiotics. When the focus of infection is treated effectively by surgical excision, 24-hour perioperative prophylaxis is typically sufficient. Patients with less severe intra-abdominal infections, including acute diverticulitis and certain forms of acute appendicitis, may be treated non-operatively.</p><p>In complicated IAIs, the infectious process extends beyond a singularly affected organ, and causes either localized peritonitis or diffuse peritonitis. The treatment of patients with complicated intra-abdominal infections involves both source control and antibiotic therapy.</p><p>Intra-abdominal infections are further classified in two groups: community-acquired intra-abdominal infections (CA-IAIs) and healthcare-associated intra-abdominal infections (HA-IAIs). CA-IAIs are acquired directly in the community while HA-IAIs develop in hospitalized patients or residents of long-term healthcare facilities. HA-IAIs are associated with higher rates of mortality due to the patients’ poorer underlying health and an increased likelihood of infection by multi-drug resistant microorganisms.</p><p>Source control encompasses all measures undertaken to eliminate the source of infection and to control ongoing contamination.</p><p>The most common source of infection in community-acquired intra-abdominal infections is the appendix, followed by the colon, and then the stomach. Dehiscence complicates 5-10% of intra-abdominal bowel anastomoses and is associated with high rates of mortality [<xref ref-type="bibr" rid="B2">2</xref>].</p><p>Ultrasound- and CT-guided percutaneous drainage of abdominal and extra-peritoneal abscesses have proven to be safe and effective in select patients [<xref ref-type="bibr" rid="B3">3</xref>-<xref ref-type="bibr" rid="B10">10</xref>].</p><p>Surgery is the most important therapeutic recourse for controlling intra-abdominal infections.</p><p>Generally, the choice of the procedure depends on the anatomical source of infection, on the degree of peritoneal inflammation, on the generalized septic response and on the patient’s general conditions.</p><p>Patients suffering from severe peritonitis are prone to persisting intra-abdominal sepsis, even when the source of infection has been neutralized. Timely re-laparotomy is the only possible known surgical recourse, capable to significantly improve patient outcome in these cases.</p><p>In the event of secondary peritonitis, the decision and timing of re-laparotomy is largely subjective and is often based on a surgeon’s professional experience. Factors indicative of progressive or persistent organ failure during early postoperative follow-up analysis are the strongest indicators of ongoing infection and suggest positive findings upon re-laparotomy [<xref ref-type="bibr" rid="B11">11</xref>-<xref ref-type="bibr" rid="B13">13</xref>].</p><p>Three methods of localized, mechanical management of abdominal sepsis following the initial laparotomy, which was performed for purposes of source control, are currently debated within the medical community: open-abdomen, planned re-laparotomy and on-demand re-laparotomy</p><p>Antimicrobial therapy plays an integral role in the management of intra-abdominal infections, especially in critically ill patients requiring immediate empiric antibiotic therapy.</p><p>Empiric antibiotic therapy accounts for the most frequently isolated microorganisms as well as any local trends of antibiotic resistance.</p><p>The major pathogens involved in community-acquired intra-abdominal infections are Enterobacteriaceae and anaerobic microbes (especially B. fragilis).</p><p>An antimicrobial-based approach to treating intra-abdominal infections involves a delicate balance between the optimization of empirical therapy, which has been shown to improve clinical outcomes, and the reduction of excessive antimicrobial use, which has been proven to increase the rate of emergence of antimicrobial-resistant strains.</p><p>The threat of antimicrobial resistance is one of the major challenges associated with the antimicrobial management of complicated intra-abdominal infections.</p><p>The recent and rapid spread of serine carbapenemases in Klebsiella pneumoniae (KPC) has become an important concern when administering antimicrobial therapy in hospitals worldwide [<xref ref-type="bibr" rid="B14">14</xref>].</p><p>The growing emergence of multidrug-resistant bacteria and the limited availability of new antibiotics to counteract them has brought about an impending crisis with alarming implications (especially regarding gram-negative microorganisms).</p></sec><sec sec-type="methods"><title>Methods</title><sec><title>Aim</title><p>The purpose of the study is to describe the clini-cal, microbiological, and treatment profiles of both community-associated and healthcare-acquired complicated intra-abdominal infections (IAIs) in a worldwide context.</p><p>Patients older than 18 years with both community-acquired and healthcare-associated intra-abdominal infections will be included in the database.</p><p>In Europe, the CIAO Study has recently ended, concluding a six-month, multicenter observational study across twenty European countries. The study’s findings have recently been published [<xref ref-type="bibr" rid="B15">15</xref>].</p><p>Given the promising results of the CIAO Study, the World Society of Emergency Surgery (WSES) has designed a prospective observational study investigating the management of complicated intra-abdominal infections in a worldwide context.</p></sec><sec><title>Study population</title><p>The CIAOW study (Complicated Intra-Abdominal infection Observational Worldwide Study) is a multicenter observational study currently underway in 57 medical institutions worldwide. The study includes patients undergoing surgery or interventional drainage to address complicated IAIs.</p><p>Medical institutions from each continent participate in the study. The geographical distribution of the participating centers is represented in Figure <xref ref-type="fig" rid="F1">1</xref>.</p><fig id="F1" position="float"><label>Figure 1</label><caption><p>Participating centers for each continent.</p></caption><graphic xlink:href="1749-7922-8-1-1"></graphic></fig></sec><sec><title>Study design</title><p>The study does not attempt to change or modify the laboratory or clinical practices of the participating physicians, and neither informed consent nor formal approval by an Ethics Committee has been required.</p><p>The study meets the standards outlined in the Declaration of Helsinki and Good Epidemiological Practices.</p><p>The study is monitored by the coordination center, which investigates and verifies missing or unclear data submitted to the central database. It is performed under the direct supervision of the board of directors of WSES.</p></sec><sec><title>Data collection</title><p>In each center, the coordinator collects and compiles data in an online case report system.These data include the following: (i) patient and disease characteristics, i.e., demographic data, type of infection (community- or healthcare-acquired), severity criteria, previous curative antibiotic therapy administered in the 7 days preceding surgery; (ii) origin of infection and surgical procedures performed; and (iii) microbiological data, i.e., identification of bacteria and microbial pathogens within the peritoneal fluid, the presence of yeasts (if applicable), and the antibiotic susceptibilities of bacterial isolates.</p><p>The primary endpoints include the following:</p><p>•Clinical profiles of intra-abdominal infections</p><p>•Epidemiological profiles (epidemiology of the microorganisms isolated from intra-abdominal samples and these organisms’ resistance to antibiotics)</p><p>•Management profiles</p></sec><sec><title>Statistical analysis</title><p>At the end of the six-month study period statistical comparisons will be performed using the Student’s t-test, χ2 analysis, or the Kruskall–Wallis/Wilcoxon tests, as dictated by the natural parameters of the data. Statistical significance will be defined as a P-value less than 0.05 (P < 0.05). Multivariate analysis will be carried out by means of stepwise logistic regressions in order to assess the predictive factors of mortality during hospitalization. Adjusted odds ratios (OR) and their 95% confidence intervals (CI) will also be included.</p></sec><sec><title>Inclusion criteria</title><p>•Patients older than 18 years</p><p>•Community- and healthcare-acquired complicated intra-abdominal infections</p></sec><sec><title>Exclusion criteria</title><p>•Age under 18 years old</p><p>•Pancreatitis</p><p>•Primary peritonitis.</p></sec></sec><sec><title>Preliminary results</title><sec><title>Patients</title><p>This preliminary report includes all data from the first two months of the six-month study period.</p><p>702 patients with a mean age of 49.2 years (range 18–98) were enrolled in the study. 272 patients (38.7%) were women and 430 (62.3%) were men. Among these patients, 615 (87.6%) were affected by community-acquired IAIs while the remaining 87 (12.4%) suffered from healthcare-associated infections.</p><p>304 patients (43.3%) were affected by generalized peritonitis while 398 (57.7%) suffered from localized peritonitis or abscesses.</p><p>112 patients (15.9%) were admitted in critical condition (severe sepsis, septic shock).</p></sec><sec><title>Source control</title><p>The various sources of infection are outlined in Table <xref ref-type="table" rid="T1">1</xref>. The most frequent source of infection was acute appendicitis. 243 cases were attributable to this condition.</p><table-wrap position="float" id="T1"><label>Table 1</label><caption><p>Source of infection</p></caption><table frame="hsides" rules="groups" border="1"><colgroup><col align="left"></col><col align="left"></col></colgroup><thead valign="top"><tr><th align="left" valign="bottom"><bold>Source of infection</bold><hr></hr></th><th align="left" valign="bottom"><bold>Patients</bold><hr></hr></th></tr><tr><th align="left"> </th><th align="left"><bold>N 702 (100%)</bold></th></tr></thead><tbody valign="top"><tr><td align="left" valign="bottom">Appendicitis<hr></hr></td><td align="left" valign="bottom">243 (34.6%)<hr></hr></td></tr><tr><td align="left" valign="bottom">Cholecystitis<hr></hr></td><td align="left" valign="bottom">104 (14.8%)<hr></hr></td></tr><tr><td align="left" valign="bottom">Post-operative<hr></hr></td><td align="left" valign="bottom">53 (7.5%)<hr></hr></td></tr><tr><td align="left" valign="bottom">Colonic non diverticular perforation<hr></hr></td><td align="left" valign="bottom">38 (5.4%)<hr></hr></td></tr><tr><td align="left" valign="bottom">Gastroduodenal perforations<hr></hr></td><td align="left" valign="bottom">100 (14.2%)<hr></hr></td></tr><tr><td align="left" valign="bottom">Diverticulitis<hr></hr></td><td align="left" valign="bottom">40 (5.7%)<hr></hr></td></tr><tr><td align="left" valign="bottom">Small bowel perforation<hr></hr></td><td align="left" valign="bottom">53 (7.5%)<hr></hr></td></tr><tr><td align="left" valign="bottom">Others<hr></hr></td><td align="left" valign="bottom">52 (7.4%)<hr></hr></td></tr><tr><td align="left" valign="bottom">PID<hr></hr></td><td align="left" valign="bottom">8 (1.1%)<hr></hr></td></tr><tr><td align="left">Post traumatic perforation</td><td align="left">11 (1.6%)</td></tr></tbody></table></table-wrap><p>The most frequently performed procedure employed to address complicated appendicitis was the open appendectomy. 136 patients (55.9%) admitted for complicated appendicitis underwent open appendectomies: 95 patients (69.8%) for localized infection or abscesses and 41 patients (31.2%) for generalized peritonitis. A laparoscopic appendectomy was performed on 93 patients (39.4%) presenting with complicated acute appendicitis, 82 (88.2%) and 11 (11.8%) of whom underwent the procedure for localized peritonitis/abscesses and generalized peritonitis, respectively. Open colonic resection was performed on 1 patient to address complicated appendicitis. In the other cases of complicated appendicitis, conservative treatment (percutaneous drainage, surgical drainage, and non-operative treatment) was performed. 7 (3%) patients underwent percutaneous drainage to address appendicular abscesses.</p><p>For patients with complicated acute cholecystitis (104 cases), the most frequently performed procedure to address cholecystitis was the open cholecystectomy. 53 cholecystitis patients (51%) underwent this procedure. A laparoscopic cholecystectomy was performed on 27 patients (26%). In the remaining cases, conservative treatment methods (percutaneous drainage, non-operative treatment) were alternatively employed.</p><p>Among the patients with complicated diverticulitis (40) the Hartmann resection was the most frequently performed procedure. 12 patients (30%) underwent a Hartmann resection. All these resections were open procedures. 8 of these patients underwent a Hartmann resection for generalized peritonitis, while the remaining 4 underwent the same procedure for localized peritonitis or abscesses.</p><p>Colo-rectal resection was performed in 11 cases (27.5%) (4 with and 7 without stoma protection).</p><p>The other patients received conservative treatment (percutaneous drainage, non-operative treatment, surgical drainage and stoma). Only two (5%) underwent laparoscopic lavage and drainage.</p><p>Of the 100 patients with gastro-duodenal perforations, the most frequent surgical procedure was gastro-duodenal suture. It was performed in 91 patients (91%): 85 patients underwent open gastro-duodenal suture and 6 patients underwent laparoscopic gastro-duodenal suture. Four (4%) patients underwent gastro-duodenal resection. The remaining patients (5%) received conservative treatment (non-operative treatment, surgical drainage).</p><p>Among the 53 patients with small bowel perforations, 35 underwent open small bowel resection (79.5%) and one (4.5%) underwent laparoscopic small bowel resection. Fourteen patients were treated by stoma. Two patients were treated by open drainage</p><p>Among the 38 patients with colonic non-diverticular perforation, 15 patients (66%) underwent open Hartmann resection, 1 patient (2.6%) underwent laparoscopic Hartmann resection, 9 (25%) underwent open resection with anastomosis and without stoma protection, and 4 underwent open resection with stoma protection (10.5%).</p></sec><sec><title>Microbiology</title><p>Intraperitoneal specimens were collected from 415 (59.1%) patients.</p><p>Intraperitoneal specimens were isolated from 336 of the 615 patients with community-acquired intra-abdominal infections (54.6%). Among the remaining 87 patients with healthcare-associated intra-abdominal infections, intraperitoneal specimens were collected from 79 patients (90.9%).</p><p>The major pathogens involved in intra-abdominal infections were found to be Enterobacteriaceae.</p><p>The aerobic bacteria identified in samples of peritoneal fluid are reported in Table <xref ref-type="table" rid="T2">2</xref>.</p><table-wrap position="float" id="T2"><label>Table 2</label><caption><p>Aerobic bacteria identified in peritoneal fluid</p></caption><table frame="hsides" rules="groups" border="1"><colgroup><col align="left"></col><col align="left"></col></colgroup><thead valign="top"><tr><th align="left"><bold>Total</bold></th><th align="left"><bold>455 (100%)</bold></th></tr></thead><tbody valign="top"><tr><td align="left" valign="bottom"><bold>Aerobic gram-negative bacteria</bold><hr></hr></td><td align="left" valign="bottom"><bold>352</bold><hr></hr></td></tr><tr><td align="left" valign="bottom"> Escherichia coli<hr></hr></td><td align="left" valign="bottom">226(49.7%)<hr></hr></td></tr><tr><td align="left" valign="bottom"> (Escherichia coli resistant to third generation cephalosporins)<hr></hr></td><td align="left" valign="bottom">37 (8.1%)<hr></hr></td></tr><tr><td align="left" valign="bottom"> Klebsiella pneuumoniae<hr></hr></td><td align="left" valign="bottom">53 (11.6%)<hr></hr></td></tr><tr><td align="left" valign="bottom"> (Klebsiella pneumoniae resistant to third generation cephalosporins)<hr></hr></td><td align="left" valign="bottom">13 (2.9%)<hr></hr></td></tr><tr><td align="left" valign="bottom"> Klebsiella oxytoca<hr></hr></td><td align="left" valign="bottom">3 (0.7%)<hr></hr></td></tr><tr><td align="left" valign="bottom"> Enterobacter<hr></hr></td><td align="left" valign="bottom">10 (2.2%)<hr></hr></td></tr><tr><td align="left" valign="bottom"> Proteus<hr></hr></td><td align="left" valign="bottom">13 (2.9%)<hr></hr></td></tr><tr><td align="left" valign="bottom"> Pseudomonas<hr></hr></td><td align="left" valign="bottom">25 (5.5%)<hr></hr></td></tr><tr><td align="left" valign="bottom"> Others<hr></hr></td><td align="left" valign="bottom">22 (4.8%)<hr></hr></td></tr><tr><td align="left" valign="bottom"><bold>Aerobic gram-positive bacteria</bold><hr></hr></td><td align="left" valign="bottom"><bold>103</bold><hr></hr></td></tr><tr><td align="left" valign="bottom"> Enterococcus faecalis<hr></hr></td><td align="left" valign="bottom">27 (5.9%)<hr></hr></td></tr><tr><td align="left" valign="bottom"> Enterococcus faecium<hr></hr></td><td align="left" valign="bottom">21 (4.6%)<hr></hr></td></tr><tr><td align="left" valign="bottom"> Staphylococcus Aureus<hr></hr></td><td align="left" valign="bottom">11 (2.4%)<hr></hr></td></tr><tr><td align="left" valign="bottom"> Streptococcus spp.<hr></hr></td><td align="left" valign="bottom">29 (6.5%)<hr></hr></td></tr><tr><td align="left"> Others</td><td align="left">15 (3.3%)</td></tr></tbody></table></table-wrap><p>According to CIAOW Study data, ESBL producers were the most commonly identified drug-resistant microorganism involved in IAIs.</p><p>1 identified isolate of Klebsiella pneumoniae proved resistant to Carbapenems.</p><p>Among the identified aerobic gram-negative isolates, there were 25 isolates of Pseudomonas aeruginosa, comprising 5.5% of all identified aerobic bacteria isolates.</p><p>Among the identified aerobic gram-positive bacteria, Enterococci (E. faecalis and E. faecium) were the most prevalent, representing 10.5% of all aerobic isolates, 3 glycopeptide-resistant Enterococci were identified; 2 were glycopeptide-resistant Enterococcus faecalis isolates and 1 was glycopeptide-resistant Enterococcus faecium isolates.</p><p>Tests for anaerobes were conducted for 168 patients.</p><p>52 anaerobes were observed. The most frequently identified anaerobic pathogen was Bacteroides. 39 Bacteroides isolates were observed during the course of the study.</p><p>Additionally, 36 Candida isolates were collectively identified. 30 were Candida albicans and 6 were non-albicans Candida.</p></sec><sec><title>Outcome</title><p>The overall mortality rate was 10.1% (71/702).</p><p>68 patients (9.7%) were admitted to the intensive care unit in the early recovery phase immediately following surgery.</p><p>90 patients (12.8%) ultimately required additional surgeries; 54% of these underwent relaparotomies “on-demand”, 28.9% underwent open abdomen procedures.</p><p>According to univariate statistical analysis, a critical clinical condition (severe sepsis and septic shock) upon hospital admission was the most significant risk factor for death; indeed, the rate of patient mortality was 36.6% (41/112) among critically ill patients (patients presenting with septic shock and severe sepsis upon admission), but the mortality rate was only 5.1% (30/590) for clinically stable patients (p < 0.0001).</p><p>For patients with generalized peritonitis, the mortality rate was 18% (55/304) while patients with localized peritonitis or abscesses demonstrated a mortality rate of only 4% (16/398) (p < 0,001).</p><p>The immediate post-operative clinical course was a significant parameter for predicting mortality: the rate of patient mortality was 54.9% (51/93) among critically ill patients (patients presenting with septic shock and severe sepsis upon the immediate post-operative course), but the mortality rate was only 3.3% (20/609) for clinically stable patients (p < 0.0001).</p><p>Preliminary statistical analyses were performed using MedCalc<sup>®</sup> statistical software.</p></sec></sec><sec sec-type="conclusions"><title>Conclusion</title><p>Complicated intra-abdominal infections remain an important cause of morbidity with poor clinical prognoses.</p><p>The purpose of the CIAOW Study is to describe the epidemiological, clinical, microbiological, and treatment profiles of both community-acquired and healthcare-acquired complicated intra-abdominal infections (IAIs) based on the data collected over a six-month period (October 2012 to March 2013) from 56 medical institutions Worldwide.</p><p>The final results of the CIAOW Study will be published following the conclusion of the study period in March 2013.</p></sec><sec><title>Competing interests</title><p>The authors declare that they have no competing interests.</p></sec><sec><title>Authors’ contributions</title><p>MS designed the study and wrote the manuscript. All authors read and approved the final manuscript.</p></sec></body><back><ref-list><ref id="B1"><mixed-citation publication-type="journal"><name><surname>Sartelli</surname><given-names>M</given-names></name><name><surname>Viale</surname><given-names>P</given-names></name><name><surname>Koike</surname><given-names>K</given-names></name><name><surname>Pea</surname><given-names>F</given-names></name><name><surname>Tumietto</surname><given-names>F</given-names></name><name><surname>van Goor</surname><given-names>H</given-names></name><name><surname>Guercioni</surname><given-names>G</given-names></name><name><surname>Nespoli</surname><given-names>A</given-names></name><name><surname>Tranà</surname><given-names>C</given-names></name><name><surname>Catena</surname><given-names>F</given-names></name><name><surname>Ansaloni</surname><given-names>L</given-names></name><name><surname>Leppaniemi</surname><given-names>A</given-names></name><name><surname>Biffl</surname><given-names>W</given-names></name><name><surname>Moore</surname><given-names>FA</given-names></name><name><surname>Poggetti</surname><given-names>R</given-names></name><name><surname>Pinna</surname><given-names>AD</given-names></name><name><surname>Moore</surname><given-names>EE</given-names></name><collab>WSES consensus conference</collab><article-title>Guidelines for first-line management of intra-abdominal infections</article-title><source>World J Emerg Surg</source><year>2011</year><volume>6</volume><fpage>2</fpage><pub-id pub-id-type="doi">10.1186/1749-7922-6-2</pub-id><pub-id pub-id-type="pmid">21232143</pub-id></mixed-citation></ref><ref id="B2"><mixed-citation publication-type="journal"><name><surname>Sartelli</surname><given-names>M</given-names></name><article-title>A focus on intra-abdominal infections</article-title><source>World J Emerg Surg</source><year>2010</year><volume>5</volume><fpage>9</fpage><pub-id pub-id-type="doi">10.1186/1749-7922-5-9</pub-id><pub-id pub-id-type="pmid">20302628</pub-id></mixed-citation></ref><ref id="B3"><mixed-citation publication-type="journal"><name><surname>Azzarello</surname><given-names>G</given-names></name><name><surname>Lanteri</surname><given-names>R</given-names></name><name><surname>Rapisarda</surname><given-names>C</given-names></name><name><surname>Santangelo</surname><given-names>M</given-names></name><name><surname>Racalbuto</surname><given-names>A</given-names></name><name><surname>Minutolo</surname><given-names>V</given-names></name><name><surname>Di Cataldo</surname><given-names>A</given-names></name><name><surname>Licata</surname><given-names>A</given-names></name><article-title>Ultrasound-guided percutaneous treatment of abdominal collections</article-title><source>Chir Ital</source><year>2009</year><volume>61</volume><fpage>337</fpage><lpage>340</lpage><pub-id pub-id-type="pmid">19694236</pub-id></mixed-citation></ref><ref id="B4"><mixed-citation publication-type="journal"><name><surname>Gazelle</surname><given-names>GS</given-names></name><name><surname>Mueller</surname><given-names>PR</given-names></name><article-title>Abdominal abscess: Imaging and intervention</article-title><source>Radiol Clin North Am</source><year>1994</year><volume>32</volume><fpage>913</fpage><lpage>932</lpage><pub-id pub-id-type="pmid">8085004</pub-id></mixed-citation></ref><ref id="B5"><mixed-citation publication-type="journal"><name><surname>VanSonnenberg</surname><given-names>E</given-names></name><name><surname>Ferrucci</surname><given-names>JT</given-names></name><name><surname>Mueller</surname><given-names>PR</given-names></name><name><surname>Wittenberg</surname><given-names>J</given-names></name><name><surname>Simeone</surname><given-names>JF</given-names></name><article-title>Percutaneous drainage of abscesses and fluid collections: Technique, results, and applications</article-title><source>Radiology</source><year>1982</year><volume>142</volume><fpage>1</fpage><lpage>10</lpage><pub-id pub-id-type="pmid">7053517</pub-id></mixed-citation></ref><ref id="B6"><mixed-citation publication-type="journal"><name><surname>Bouali</surname><given-names>K</given-names></name><name><surname>Magotteaux</surname><given-names>P</given-names></name><name><surname>Jadot</surname><given-names>A</given-names></name><name><surname>Saive</surname><given-names>C</given-names></name><name><surname>Lombard</surname><given-names>R</given-names></name><name><surname>Weerts</surname><given-names>J</given-names></name><name><surname>Dallemagne</surname><given-names>B</given-names></name><name><surname>Jehaes</surname><given-names>C</given-names></name><name><surname>Delforge</surname><given-names>M</given-names></name><name><surname>Fontaine</surname><given-names>F</given-names></name><article-title>Percutaneous catheter drainage of abdominal abscess after abdominal surgery: Results in 121 cases</article-title><source>J Belg Radiol</source><year>1993</year><volume>76</volume><fpage>11</fpage><lpage>14</lpage><pub-id pub-id-type="pmid">8320186</pub-id></mixed-citation></ref><ref id="B7"><mixed-citation publication-type="journal"><name><surname>VanSonnenberg</surname><given-names>E</given-names></name><name><surname>Wing</surname><given-names>VW</given-names></name><name><surname>Casola</surname><given-names>G</given-names></name><name><surname>Coons</surname><given-names>HG</given-names></name><name><surname>Nakamoto</surname><given-names>SK</given-names></name><name><surname>Mueller</surname><given-names>PR</given-names></name><name><surname>Ferrucci</surname><given-names>JT</given-names><suffix>Jr</suffix></name><name><surname>Halasz</surname><given-names>NA</given-names></name><name><surname>Simeone</surname><given-names>JF</given-names></name><article-title>Temporizing effect of percutaneous drainage of complicated abscesses in critically ill patients</article-title><source>Am J Roentgenol</source><year>1984</year><volume>142</volume><fpage>821</fpage><lpage>826</lpage><pub-id pub-id-type="doi">10.2214/ajr.142.4.821</pub-id><pub-id pub-id-type="pmid">6199965</pub-id></mixed-citation></ref><ref id="B8"><mixed-citation publication-type="journal"><name><surname>Bufalari</surname><given-names>A</given-names></name><name><surname>Giustozzi</surname><given-names>G</given-names></name><name><surname>Moggi</surname><given-names>L</given-names></name><article-title>Postoperative intra-abdominal abscesses: Percutaneous versus surgical treatment</article-title><source>Acta Chir Belg</source><year>1996</year><volume>96</volume><issue>5</issue><fpage>197</fpage><lpage>200</lpage><pub-id pub-id-type="pmid">8950379</pub-id></mixed-citation></ref><ref id="B9"><mixed-citation publication-type="journal"><name><surname>VanSonnenberg</surname><given-names>E</given-names></name><name><surname>Mueller</surname><given-names>PR</given-names></name><name><surname>Ferrucci</surname><given-names>JT</given-names><suffix>Jr</suffix></name><article-title>Percutaneous drainage of 250 abdominal abscesses and fluid collections. I. Results, failures, and complications</article-title><source>Radiology</source><year>1984</year><volume>151</volume><fpage>337</fpage><lpage>341</lpage><pub-id pub-id-type="pmid">6709901</pub-id></mixed-citation></ref><ref id="B10"><mixed-citation publication-type="journal"><name><surname>Jaffe</surname><given-names>TA</given-names></name><name><surname>Nelson</surname><given-names>RC</given-names></name><name><surname>DeLong</surname><given-names>D</given-names></name><name><surname>Paulson</surname><given-names>EK</given-names></name><article-title>Practice Patterns in Percutaneous Image-guided Intra-abdominal Abscess Drainage: Survey of Academic and Private Practice Centres</article-title><source>Radiology</source><year>2004</year><volume>233</volume><fpage>750</fpage><lpage>756</lpage><pub-id pub-id-type="doi">10.1148/radiol.2333032063</pub-id><pub-id pub-id-type="pmid">15516608</pub-id></mixed-citation></ref><ref id="B11"><mixed-citation publication-type="journal"><name><surname>van Ruler</surname><given-names>O</given-names></name><name><surname>Lamme</surname><given-names>B</given-names></name><name><surname>Gouma</surname><given-names>DJ</given-names></name><name><surname>Reitsma</surname><given-names>JB</given-names></name><name><surname>Boermeester</surname><given-names>MA</given-names></name><article-title>Variables associated with positive findings at relaparotomy in patients with secondary peritonitis</article-title><source>Crit Care Med</source><year>2007</year><volume>35</volume><issue>2</issue><fpage>468</fpage><lpage>476</lpage><pub-id pub-id-type="doi">10.1097/01.CCM.0000253399.03545.2D</pub-id><pub-id pub-id-type="pmid">17205025</pub-id></mixed-citation></ref><ref id="B12"><mixed-citation publication-type="journal"><name><surname>Hutchins</surname><given-names>RR</given-names></name><name><surname>Gunning</surname><given-names>MP</given-names></name><name><surname>Lucas</surname><given-names>DN</given-names></name><name><surname>Allen-Mersh</surname><given-names>TG</given-names></name><name><surname>Soni</surname><given-names>NC</given-names></name><article-title>Relaparotomy for suspected intraperitoneal sepsis after abdominal surgery</article-title><source>World J Surg</source><year>2004</year><volume>28</volume><issue>2</issue><fpage>137</fpage><lpage>141</lpage><pub-id pub-id-type="doi">10.1007/s00268-003-7067-8</pub-id><pub-id pub-id-type="pmid">14708056</pub-id></mixed-citation></ref><ref id="B13"><mixed-citation publication-type="journal"><name><surname>Lamme</surname><given-names>B</given-names></name><name><surname>Mahler</surname><given-names>CW</given-names></name><name><surname>van Ruler</surname><given-names>O</given-names></name><name><surname>Gouma</surname><given-names>DJ</given-names></name><name><surname>Reitsma</surname><given-names>JB</given-names></name><name><surname>Boermeester</surname><given-names>MA</given-names></name><article-title>Clinical predictors of ongoing infection in secondary peritonitis: systematic review</article-title><source>World J Surg</source><year>2006</year><volume>30</volume><issue>12</issue><fpage>2170</fpage><lpage>2181</lpage><pub-id pub-id-type="doi">10.1007/s00268-005-0333-1</pub-id><pub-id pub-id-type="pmid">17102920</pub-id></mixed-citation></ref><ref id="B14"><mixed-citation publication-type="journal"><name><surname>Hawser</surname><given-names>SP</given-names></name><name><surname>Bouchillon</surname><given-names>SK</given-names></name><name><surname>Lascols</surname><given-names>C</given-names></name><name><surname>Hackel</surname><given-names>M</given-names></name><name><surname>Hoban</surname><given-names>DJ</given-names></name><name><surname>Badal</surname><given-names>RE</given-names></name><name><surname>Woodford</surname><given-names>N</given-names></name><name><surname>Livermore</surname><given-names>DM</given-names></name><article-title>Susceptibility of Klebsiella pneumoniae isolates from intra-abdominal infections and molecular characterization of ertapenem-resistant isolates</article-title><source>Antimicrob Agents Chemother</source><year>2011</year><volume>55</volume><issue>8</issue><fpage>3917</fpage><lpage>3921</lpage><pub-id pub-id-type="doi">10.1128/AAC.00070-11</pub-id><pub-id pub-id-type="pmid">21670192</pub-id></mixed-citation></ref><ref id="B15"><mixed-citation publication-type="journal"><name><surname>Sartelli</surname><given-names>M</given-names></name><name><surname>Catena</surname><given-names>F</given-names></name><name><surname>Ansaloni</surname><given-names>L</given-names></name><name><surname>Leppaniemi</surname><given-names>A</given-names></name><name><surname>Taviloglu</surname><given-names>K</given-names></name><name><surname>Goor</surname><given-names>H</given-names></name><name><surname>Viale</surname><given-names>P</given-names></name><name><surname>Lazzareschi</surname><given-names>DV</given-names></name><name><surname>Coccolini</surname><given-names>F</given-names></name><name><surname>Corbella</surname><given-names>D</given-names></name><name><surname>Werra</surname><given-names>C</given-names></name><name><surname>Marrelli</surname><given-names>D</given-names></name><name><surname>Colizza</surname><given-names>S</given-names></name><name><surname>Scibè</surname><given-names>R</given-names></name><name><surname>Alis</surname><given-names>H</given-names></name><name><surname>Torer</surname><given-names>N</given-names></name><name><surname>Navarro</surname><given-names>S</given-names></name><name><surname>Sakakushev</surname><given-names>B</given-names></name><name><surname>Massalou</surname><given-names>D</given-names></name><name><surname>Augustin</surname><given-names>G</given-names></name><name><surname>Catani</surname><given-names>M</given-names></name><name><surname>Kauhanen</surname><given-names>S</given-names></name><name><surname>Pletinckx</surname><given-names>P</given-names></name><name><surname>Kenig</surname><given-names>J</given-names></name><name><surname>Saverio</surname><given-names>S</given-names></name><name><surname>Jovine</surname><given-names>E</given-names></name><name><surname>Guercioni</surname><given-names>G</given-names></name><name><surname>Skrovina</surname><given-names>M</given-names></name><name><surname>Diaz-Nieto</surname><given-names>R</given-names></name><name><surname>Ferrero</surname><given-names>A</given-names></name><etal></etal><article-title>Complicated intra-abdominal infections in Europe: a comprehensive review of the CIAO study</article-title><source>World J Emerg Surg</source><year>2012</year><volume>7</volume><issue>1</issue><fpage>36</fpage><pub-id pub-id-type="doi">10.1186/1749-7922-7-36</pub-id><pub-id pub-id-type="pmid">23190741</pub-id></mixed-citation></ref></ref-list></back></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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