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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Facilitating a Culture of Responsible and Effective Sharing of Cancer Genome Data</title><author><name sortKey="Siu, Lillian L" sort="Siu, Lillian L" uniqKey="Siu L" first="Lillian L." last="Siu">Lillian L. Siu</name><affiliation><nlm:aff id="A1">Princess Margaret Cancer Centre, University of Toronto, Toronto, Canada</nlm:aff></affiliation></author><author><name sortKey="Lawler, Mark" sort="Lawler, Mark" uniqKey="Lawler M" first="Mark" last="Lawler">Mark Lawler</name><affiliation><nlm:aff id="A2">Centre for Cancer Research and Cell Biology, Queen’s University, Belfast, UK</nlm:aff></affiliation></author><author><name sortKey="Haussler, David" sort="Haussler, David" uniqKey="Haussler D" first="David" last="Haussler">David Haussler</name><affiliation><nlm:aff id="A3">UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA</nlm:aff></affiliation></author><author><name sortKey="Knoppers, Bartha Maria" sort="Knoppers, Bartha Maria" uniqKey="Knoppers B" first="Bartha Maria" last="Knoppers">Bartha Maria Knoppers</name><affiliation><nlm:aff id="A4">Centre of Genomics and Policy, McGill University, Montreal, Canada</nlm:aff></affiliation></author><author><name sortKey="Lewin, Jeremy" sort="Lewin, Jeremy" uniqKey="Lewin J" first="Jeremy" last="Lewin">Jeremy Lewin</name><affiliation><nlm:aff id="A1">Princess Margaret Cancer Centre, University of Toronto, Toronto, Canada</nlm:aff></affiliation></author><author><name sortKey="Vis, Daniel J" sort="Vis, Daniel J" uniqKey="Vis D" first="Daniel J." last="Vis">Daniel J. Vis</name><affiliation><nlm:aff id="A5">The Netherlands Cancer Institute, Amsterdam, the Netherlands</nlm:aff></affiliation></author><author><name sortKey="Liao, Rachel G" sort="Liao, Rachel G" uniqKey="Liao R" first="Rachel G." last="Liao">Rachel G. Liao</name><affiliation><nlm:aff id="A6">The Global Alliance for Genomics and Health, Toronto, Canada and the Broad Institute, Cambridge, MA, USA</nlm:aff></affiliation></author><author><name sortKey="Andre, Fabrice" sort="Andre, Fabrice" uniqKey="Andre F" first="Fabrice" last="Andre">Fabrice Andre</name><affiliation><nlm:aff id="A7">Gustave Roussy and Université Paris Sud, Villejuif, France</nlm:aff></affiliation></author><author><name sortKey="Banks, Ian" sort="Banks, Ian" uniqKey="Banks I" first="Ian" last="Banks">Ian Banks</name><affiliation><nlm:aff id="A8">Patient’s Advocacy Committee, European Cancer Organization, Brussels, Belgium</nlm:aff></affiliation></author><author><name sortKey="Barrett, J Carl" sort="Barrett, J Carl" uniqKey="Barrett J" first="J. Carl" last="Barrett">J. Carl Barrett</name><affiliation><nlm:aff id="A9">Translational Sciences, Oncology iMED, AstraZeneca, Waltham, MA, USA</nlm:aff></affiliation></author><author><name sortKey="Caldas, Carlos" sort="Caldas, Carlos" uniqKey="Caldas C" first="Carlos" last="Caldas">Carlos Caldas</name><affiliation><nlm:aff id="A10">University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Camargo, Anamaria Aranha" sort="Camargo, Anamaria Aranha" uniqKey="Camargo A" first="Anamaria Aranha" last="Camargo">Anamaria Aranha Camargo</name><affiliation><nlm:aff id="A11">Hospital Sírio-Libanês, São Paulo, Brazil</nlm:aff></affiliation></author><author><name sortKey="Fitzgerald, Rebecca C" sort="Fitzgerald, Rebecca C" uniqKey="Fitzgerald R" first="Rebecca C." last="Fitzgerald">Rebecca C. Fitzgerald</name><affiliation><nlm:aff id="A10">University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Mao, Mao" sort="Mao, Mao" uniqKey="Mao M" first="Mao" last="Mao">Mao Mao</name><affiliation><nlm:aff id="A12">Yonsei Cancer Research Institute, Yonsei University College of Medicine, Seoul, Korea</nlm:aff></affiliation></author><author><name sortKey="Mattison, John E" sort="Mattison, John E" uniqKey="Mattison J" first="John E." last="Mattison">John E. Mattison</name><affiliation><nlm:aff id="A13">Kaiser Permanente, Pasadena, CA, USA</nlm:aff></affiliation></author><author><name sortKey="Pao, William" sort="Pao, William" uniqKey="Pao W" first="William" last="Pao">William Pao</name><affiliation><nlm:aff id="A14">Roche Innovation Center Basel, Pharma Research and Early Development, Roche, Basel, Switzerland</nlm:aff></affiliation></author><author><name sortKey="Sellers, William R" sort="Sellers, William R" uniqKey="Sellers W" first="William R." last="Sellers">William R. Sellers</name><affiliation><nlm:aff id="A15">Novartis Institutes for Biomedical Research, Cambridge, MA, USA</nlm:aff></affiliation></author><author><name sortKey="Sullivan, Patrick" sort="Sullivan, Patrick" uniqKey="Sullivan P" first="Patrick" last="Sullivan">Patrick Sullivan</name><affiliation><nlm:aff id="A16">Advocacy for Canadian Children Oncology Network, Vancouver, Canada</nlm:aff></affiliation></author><author><name sortKey="Teh, Bin Tean" sort="Teh, Bin Tean" uniqKey="Teh B" first="Bin Tean" last="Teh">Bin Tean Teh</name><affiliation><nlm:aff id="A17">National Cancer Centre Singapore, Singapore</nlm:aff></affiliation></author><author><name sortKey="Ward, Robyn" sort="Ward, Robyn" uniqKey="Ward R" first="Robyn" last="Ward">Robyn Ward</name><affiliation><nlm:aff id="A18">University of Queensland, St. Lucia, Australia</nlm:aff></affiliation></author><author><name sortKey="Zenklusen, Jean Claude" sort="Zenklusen, Jean Claude" uniqKey="Zenklusen J" first="Jean Claude" last="Zenklusen">Jean Claude Zenklusen</name><affiliation><nlm:aff id="A19">The Cancer Genome Atlas, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA</nlm:aff></affiliation></author><author><name sortKey="Sawyers, Charles L" sort="Sawyers, Charles L" uniqKey="Sawyers C" first="Charles L" last="Sawyers">Charles L. Sawyers</name><affiliation><nlm:aff id="A20">Memorial Sloan Kettering Cancer Center, New York, NY, USA</nlm:aff></affiliation></author><author><name sortKey="Voest, Emile E" sort="Voest, Emile E" uniqKey="Voest E" first="Emile E." last="Voest">Emile E. Voest</name><affiliation><nlm:aff id="A5">The Netherlands Cancer Institute, Amsterdam, the Netherlands</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27149219</idno><idno type="pmc">4995884</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995884</idno><idno type="RBID">PMC:4995884</idno><idno type="doi">10.1038/nm.4089</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">002172</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002172</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Facilitating a Culture of Responsible and Effective Sharing of Cancer Genome Data</title><author><name sortKey="Siu, Lillian L" sort="Siu, Lillian L" uniqKey="Siu L" first="Lillian L." last="Siu">Lillian L. Siu</name><affiliation><nlm:aff id="A1">Princess Margaret Cancer Centre, University of Toronto, Toronto, Canada</nlm:aff></affiliation></author><author><name sortKey="Lawler, Mark" sort="Lawler, Mark" uniqKey="Lawler M" first="Mark" last="Lawler">Mark Lawler</name><affiliation><nlm:aff id="A2">Centre for Cancer Research and Cell Biology, Queen’s University, Belfast, UK</nlm:aff></affiliation></author><author><name sortKey="Haussler, David" sort="Haussler, David" uniqKey="Haussler D" first="David" last="Haussler">David Haussler</name><affiliation><nlm:aff id="A3">UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA</nlm:aff></affiliation></author><author><name sortKey="Knoppers, Bartha Maria" sort="Knoppers, Bartha Maria" uniqKey="Knoppers B" first="Bartha Maria" last="Knoppers">Bartha Maria Knoppers</name><affiliation><nlm:aff id="A4">Centre of Genomics and Policy, McGill University, Montreal, Canada</nlm:aff></affiliation></author><author><name sortKey="Lewin, Jeremy" sort="Lewin, Jeremy" uniqKey="Lewin J" first="Jeremy" last="Lewin">Jeremy Lewin</name><affiliation><nlm:aff id="A1">Princess Margaret Cancer Centre, University of Toronto, Toronto, Canada</nlm:aff></affiliation></author><author><name sortKey="Vis, Daniel J" sort="Vis, Daniel J" uniqKey="Vis D" first="Daniel J." last="Vis">Daniel J. Vis</name><affiliation><nlm:aff id="A5">The Netherlands Cancer Institute, Amsterdam, the Netherlands</nlm:aff></affiliation></author><author><name sortKey="Liao, Rachel G" sort="Liao, Rachel G" uniqKey="Liao R" first="Rachel G." last="Liao">Rachel G. Liao</name><affiliation><nlm:aff id="A6">The Global Alliance for Genomics and Health, Toronto, Canada and the Broad Institute, Cambridge, MA, USA</nlm:aff></affiliation></author><author><name sortKey="Andre, Fabrice" sort="Andre, Fabrice" uniqKey="Andre F" first="Fabrice" last="Andre">Fabrice Andre</name><affiliation><nlm:aff id="A7">Gustave Roussy and Université Paris Sud, Villejuif, France</nlm:aff></affiliation></author><author><name sortKey="Banks, Ian" sort="Banks, Ian" uniqKey="Banks I" first="Ian" last="Banks">Ian Banks</name><affiliation><nlm:aff id="A8">Patient’s Advocacy Committee, European Cancer Organization, Brussels, Belgium</nlm:aff></affiliation></author><author><name sortKey="Barrett, J Carl" sort="Barrett, J Carl" uniqKey="Barrett J" first="J. Carl" last="Barrett">J. Carl Barrett</name><affiliation><nlm:aff id="A9">Translational Sciences, Oncology iMED, AstraZeneca, Waltham, MA, USA</nlm:aff></affiliation></author><author><name sortKey="Caldas, Carlos" sort="Caldas, Carlos" uniqKey="Caldas C" first="Carlos" last="Caldas">Carlos Caldas</name><affiliation><nlm:aff id="A10">University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Camargo, Anamaria Aranha" sort="Camargo, Anamaria Aranha" uniqKey="Camargo A" first="Anamaria Aranha" last="Camargo">Anamaria Aranha Camargo</name><affiliation><nlm:aff id="A11">Hospital Sírio-Libanês, São Paulo, Brazil</nlm:aff></affiliation></author><author><name sortKey="Fitzgerald, Rebecca C" sort="Fitzgerald, Rebecca C" uniqKey="Fitzgerald R" first="Rebecca C." last="Fitzgerald">Rebecca C. Fitzgerald</name><affiliation><nlm:aff id="A10">University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Mao, Mao" sort="Mao, Mao" uniqKey="Mao M" first="Mao" last="Mao">Mao Mao</name><affiliation><nlm:aff id="A12">Yonsei Cancer Research Institute, Yonsei University College of Medicine, Seoul, Korea</nlm:aff></affiliation></author><author><name sortKey="Mattison, John E" sort="Mattison, John E" uniqKey="Mattison J" first="John E." last="Mattison">John E. Mattison</name><affiliation><nlm:aff id="A13">Kaiser Permanente, Pasadena, CA, USA</nlm:aff></affiliation></author><author><name sortKey="Pao, William" sort="Pao, William" uniqKey="Pao W" first="William" last="Pao">William Pao</name><affiliation><nlm:aff id="A14">Roche Innovation Center Basel, Pharma Research and Early Development, Roche, Basel, Switzerland</nlm:aff></affiliation></author><author><name sortKey="Sellers, William R" sort="Sellers, William R" uniqKey="Sellers W" first="William R." last="Sellers">William R. Sellers</name><affiliation><nlm:aff id="A15">Novartis Institutes for Biomedical Research, Cambridge, MA, USA</nlm:aff></affiliation></author><author><name sortKey="Sullivan, Patrick" sort="Sullivan, Patrick" uniqKey="Sullivan P" first="Patrick" last="Sullivan">Patrick Sullivan</name><affiliation><nlm:aff id="A16">Advocacy for Canadian Children Oncology Network, Vancouver, Canada</nlm:aff></affiliation></author><author><name sortKey="Teh, Bin Tean" sort="Teh, Bin Tean" uniqKey="Teh B" first="Bin Tean" last="Teh">Bin Tean Teh</name><affiliation><nlm:aff id="A17">National Cancer Centre Singapore, Singapore</nlm:aff></affiliation></author><author><name sortKey="Ward, Robyn" sort="Ward, Robyn" uniqKey="Ward R" first="Robyn" last="Ward">Robyn Ward</name><affiliation><nlm:aff id="A18">University of Queensland, St. Lucia, Australia</nlm:aff></affiliation></author><author><name sortKey="Zenklusen, Jean Claude" sort="Zenklusen, Jean Claude" uniqKey="Zenklusen J" first="Jean Claude" last="Zenklusen">Jean Claude Zenklusen</name><affiliation><nlm:aff id="A19">The Cancer Genome Atlas, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA</nlm:aff></affiliation></author><author><name sortKey="Sawyers, Charles L" sort="Sawyers, Charles L" uniqKey="Sawyers C" first="Charles L" last="Sawyers">Charles L. Sawyers</name><affiliation><nlm:aff id="A20">Memorial Sloan Kettering Cancer Center, New York, NY, USA</nlm:aff></affiliation></author><author><name sortKey="Voest, Emile E" sort="Voest, Emile E" uniqKey="Voest E" first="Emile E." last="Voest">Emile E. Voest</name><affiliation><nlm:aff id="A5">The Netherlands Cancer Institute, Amsterdam, the Netherlands</nlm:aff></affiliation></author></analytic><series><title level="j">Nature medicine</title><idno type="ISSN">1078-8956</idno><idno type="eISSN">1546-170X</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">Rapid and affordable tumor molecular profiling has led to an explosion of clinical and genomic data poised to enhance diagnosis, prognostication and treatment of cancer. A critical point has now been reached where analysis and storage of annotated clinical and genomic information in unconnected silos will stall the advancement of precision cancer care. Information systems must be harmonized to overcome the multiple technical and logistical barriers for data sharing. Against this backdrop, the Global Alliance for Genomic Health (GA4GH) was established in 2013 to create a common framework that enables responsible, voluntary, and secure sharing of clinical and genomic data. This Perspective from the GA4GH Clinical Working Group Cancer Task Team highlights the data aggregation challenges faced by the field, suggests potential collaborative solutions, and describes how GA4GH can catalyze a harmonized data sharing culture.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">9502015</journal-id><journal-id journal-id-type="pubmed-jr-id">8791</journal-id><journal-id journal-id-type="nlm-ta">Nat Med</journal-id><journal-id journal-id-type="iso-abbrev">Nat. Med.</journal-id><journal-title-group><journal-title>Nature medicine</journal-title></journal-title-group><issn pub-type="ppub">1078-8956</issn><issn pub-type="epub">1546-170X</issn></journal-meta><article-meta><article-id pub-id-type="pmid">27149219</article-id><article-id pub-id-type="pmc">4995884</article-id><article-id pub-id-type="doi">10.1038/nm.4089</article-id><article-id pub-id-type="manuscript">NIHMS810334</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Facilitating a Culture of Responsible and Effective Sharing of Cancer Genome Data</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Siu</surname><given-names>Lillian L.</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref rid="FN2" ref-type="author-notes">*</xref></contrib><contrib contrib-type="author"><name><surname>Lawler</surname><given-names>Mark</given-names></name><xref ref-type="aff" rid="A2">2</xref><xref rid="FN2" ref-type="author-notes">*</xref><xref rid="FN1" ref-type="author-notes">ˆ</xref></contrib><contrib contrib-type="author"><name><surname>Haussler</surname><given-names>David</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Knoppers</surname><given-names>Bartha Maria</given-names></name><xref ref-type="aff" rid="A4">4</xref></contrib><contrib contrib-type="author"><name><surname>Lewin</surname><given-names>Jeremy</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Vis</surname><given-names>Daniel J.</given-names></name><xref ref-type="aff" rid="A5">5</xref></contrib><contrib contrib-type="author"><name><surname>Liao</surname><given-names>Rachel G.</given-names></name><xref ref-type="aff" rid="A6">6</xref></contrib><contrib contrib-type="author"><name><surname>Andre</surname><given-names>Fabrice</given-names></name><xref ref-type="aff" rid="A7">7</xref></contrib><contrib contrib-type="author"><name><surname>Banks</surname><given-names>Ian</given-names></name><xref ref-type="aff" rid="A8">8</xref></contrib><contrib contrib-type="author"><name><surname>Barrett</surname><given-names>J. Carl</given-names></name><xref ref-type="aff" rid="A9">9</xref></contrib><contrib contrib-type="author"><name><surname>Caldas</surname><given-names>Carlos</given-names></name><xref ref-type="aff" rid="A10">10</xref></contrib><contrib contrib-type="author"><name><surname>Camargo</surname><given-names>Anamaria Aranha</given-names></name><xref ref-type="aff" rid="A11">11</xref></contrib><contrib contrib-type="author"><name><surname>Fitzgerald</surname><given-names>Rebecca C.</given-names></name><xref ref-type="aff" rid="A10">10</xref></contrib><contrib contrib-type="author"><name><surname>Mao</surname><given-names>Mao</given-names></name><xref ref-type="aff" rid="A12">12</xref></contrib><contrib contrib-type="author"><name><surname>Mattison</surname><given-names>John E.</given-names></name><xref ref-type="aff" rid="A13">13</xref></contrib><contrib contrib-type="author"><name><surname>Pao</surname><given-names>William</given-names></name><xref ref-type="aff" rid="A14">14</xref></contrib><contrib contrib-type="author"><name><surname>Sellers</surname><given-names>William R.</given-names></name><xref ref-type="aff" rid="A15">15</xref></contrib><contrib contrib-type="author"><name><surname>Sullivan</surname><given-names>Patrick</given-names></name><xref ref-type="aff" rid="A16">16</xref></contrib><contrib contrib-type="author"><name><surname>Teh</surname><given-names>Bin Tean</given-names></name><xref ref-type="aff" rid="A17">17</xref></contrib><contrib contrib-type="author"><name><surname>Ward</surname><given-names>Robyn</given-names></name><xref ref-type="aff" rid="A18">18</xref></contrib><contrib contrib-type="author"><name><surname>ZenKlusen</surname><given-names>Jean Claude</given-names></name><xref ref-type="aff" rid="A19">19</xref></contrib><contrib contrib-type="author"><name><surname>Sawyers</surname><given-names>Charles L</given-names></name><xref ref-type="aff" rid="A20">20</xref></contrib><contrib contrib-type="author"><name><surname>Voest</surname><given-names>Emile E.</given-names></name><xref ref-type="aff" rid="A5">5</xref></contrib></contrib-group><aff id="A1"><label>1</label>Princess Margaret Cancer Centre, University of Toronto, Toronto, Canada</aff><aff id="A2"><label>2</label>Centre for Cancer Research and Cell Biology, Queen’s University, Belfast, UK</aff><aff id="A3"><label>3</label>UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA</aff><aff id="A4"><label>4</label>Centre of Genomics and Policy, McGill University, Montreal, Canada</aff><aff id="A5"><label>5</label>The Netherlands Cancer Institute, Amsterdam, the Netherlands</aff><aff id="A6"><label>6</label>The Global Alliance for Genomics and Health, Toronto, Canada and the Broad Institute, Cambridge, MA, USA</aff><aff id="A7"><label>7</label>Gustave Roussy and Université Paris Sud, Villejuif, France</aff><aff id="A8"><label>8</label>Patient’s Advocacy Committee, European Cancer Organization, Brussels, Belgium</aff><aff id="A9"><label>9</label>Translational Sciences, Oncology iMED, AstraZeneca, Waltham, MA, USA</aff><aff id="A10"><label>10</label>University of Cambridge, Cambridge, UK</aff><aff id="A11"><label>11</label>Hospital Sírio-Libanês, São Paulo, Brazil</aff><aff id="A12"><label>12</label>Yonsei Cancer Research Institute, Yonsei University College of Medicine, Seoul, Korea</aff><aff id="A13"><label>13</label>Kaiser Permanente, Pasadena, CA, USA</aff><aff id="A14"><label>14</label>Roche Innovation Center Basel, Pharma Research and Early Development, Roche, Basel, Switzerland</aff><aff id="A15"><label>15</label>Novartis Institutes for Biomedical Research, Cambridge, MA, USA</aff><aff id="A16"><label>16</label>Advocacy for Canadian Children Oncology Network, Vancouver, Canada</aff><aff id="A17"><label>17</label>National Cancer Centre Singapore, Singapore</aff><aff id="A18"><label>18</label>University of Queensland, St. Lucia, Australia</aff><aff id="A19"><label>19</label>The Cancer Genome Atlas, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA</aff><aff id="A20"><label>20</label>Memorial Sloan Kettering Cancer Center, New York, NY, USA</aff><author-notes><corresp id="FN1"><label>ˆ</label>Corresponding Author: Mark Lawler, Centre for Cancer Research and Cell Biology, Queen’s University Belfast, CCRCB, Lisburn Road 97, Belfast, BT9 7AE, United Kingdom, Phone: 44-28-9097-2931, Fax: 44-28-9097-2776, <email>mark.lawler@qub.ac.uk</email></corresp><fn id="FN2" fn-type="equal"><label>*</label><p>These authors contributed equally</p></fn></author-notes><pub-date pub-type="nihms-submitted"><day>15</day><month>8</month><year>2016</year></pub-date><pub-date pub-type="ppub"><day>5</day><month>5</month><year>2016</year></pub-date><pub-date pub-type="pmc-release"><day>24</day><month>8</month><year>2016</year></pub-date><volume>22</volume><issue>5</issue><fpage>464</fpage><lpage>471</lpage><pmc-comment>elocation-id from pubmed: 10.1038/nm.4089</pmc-comment>
<abstract><p id="P1">Rapid and affordable tumor molecular profiling has led to an explosion of clinical and genomic data poised to enhance diagnosis, prognostication and treatment of cancer. A critical point has now been reached where analysis and storage of annotated clinical and genomic information in unconnected silos will stall the advancement of precision cancer care. Information systems must be harmonized to overcome the multiple technical and logistical barriers for data sharing. Against this backdrop, the Global Alliance for Genomic Health (GA4GH) was established in 2013 to create a common framework that enables responsible, voluntary, and secure sharing of clinical and genomic data. This Perspective from the GA4GH Clinical Working Group Cancer Task Team highlights the data aggregation challenges faced by the field, suggests potential collaborative solutions, and describes how GA4GH can catalyze a harmonized data sharing culture.</p></abstract></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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