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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Genome-wide association studies identify four ER negative–specific breast cancer risk loci</title><author><name sortKey="Garcia Closas, Montserrat" sort="Garcia Closas, Montserrat" uniqKey="Garcia Closas M" first="Montserrat" last="Garcia-Closas">Montserrat Garcia-Closas</name><affiliation><nlm:aff id="A1">Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, UK</nlm:aff></affiliation><affiliation><nlm:aff id="A2">Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK</nlm:aff></affiliation></author><author><name sortKey="Couch, Fergus J" sort="Couch, Fergus J" uniqKey="Couch F" first="Fergus J" last="Couch">Fergus J. Couch</name><affiliation><nlm:aff id="A3">Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota, USA</nlm:aff></affiliation></author><author><name sortKey="Lindstrom, Sara" sort="Lindstrom, Sara" uniqKey="Lindstrom S" first="Sara" last="Lindstrom">Sara Lindstrom</name><affiliation><nlm:aff id="A4">Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA</nlm:aff></affiliation></author><author><name sortKey="Michailidou, Kyriaki" sort="Michailidou, Kyriaki" uniqKey="Michailidou K" first="Kyriaki" last="Michailidou">Kyriaki Michailidou</name><affiliation><nlm:aff id="A5">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Schmidt, Marjanka K" sort="Schmidt, Marjanka K" uniqKey="Schmidt M" first="Marjanka K" last="Schmidt">Marjanka K. Schmidt</name><affiliation><nlm:aff id="A6">Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Brook, Mark N" sort="Brook, Mark N" uniqKey="Brook M" first="Mark N" last="Brook">Mark N. Brook</name><affiliation><nlm:aff id="A1">Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, UK</nlm:aff></affiliation></author><author><name sortKey="Orr, Nick" sort="Orr, Nick" uniqKey="Orr N" first="Nick" last="Orr">Nick Orr</name><affiliation><nlm:aff id="A2">Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK</nlm:aff></affiliation></author><author><name sortKey="Rhie, Suhn Kyong" sort="Rhie, Suhn Kyong" uniqKey="Rhie S" first="Suhn Kyong" last="Rhie">Suhn Kyong Rhie</name><affiliation><nlm:aff id="A7">Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA</nlm:aff></affiliation></author><author><name sortKey="Riboli, Elio" sort="Riboli, Elio" uniqKey="Riboli E" first="Elio" last="Riboli">Elio Riboli</name><affiliation><nlm:aff id="A8">School of Public Health, Imperial College, London, UK</nlm:aff></affiliation></author><author><name sortKey="Feigelson, Heather S" sort="Feigelson, Heather S" uniqKey="Feigelson H" first="Heather S" last="Feigelson">Heather S Feigelson</name><affiliation><nlm:aff id="A9">Kaiser Permanente, Institute for Health Research, Denver, Colorado, USA</nlm:aff></affiliation></author><author><name sortKey="Le Marchand, Loic" sort="Le Marchand, Loic" uniqKey="Le Marchand L" first="Loic" last="Le Marchand">Loic Le Marchand</name><affiliation><nlm:aff id="A10">Epidemiology Program, Cancer Research Center, University of Hawaii, Honolulu, Hawaii, USA</nlm:aff></affiliation></author><author><name sortKey="Buring, Julie E" sort="Buring, Julie E" uniqKey="Buring J" first="Julie E" last="Buring">Julie E. Buring</name><affiliation><nlm:aff id="A11">Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, USA</nlm:aff></affiliation></author><author><name sortKey="Eccles, Diana" sort="Eccles, Diana" uniqKey="Eccles D" first="Diana" last="Eccles">Diana Eccles</name><affiliation><nlm:aff id="A12">Faculty of Medicine, University of Southampton, Southampton, UK</nlm:aff></affiliation></author><author><name sortKey="Miron, Penelope" sort="Miron, Penelope" uniqKey="Miron P" first="Penelope" last="Miron">Penelope Miron</name><affiliation><nlm:aff id="A13">Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA</nlm:aff></affiliation></author><author><name sortKey="Fasching, Peter A" sort="Fasching, Peter A" uniqKey="Fasching P" first="Peter A" last="Fasching">Peter A. Fasching</name><affiliation><nlm:aff id="A14">Department of Gynecology and Obstetrics, University Breast Center Franconia, University Hospital Erlangen, Erlangen, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A15">Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA</nlm:aff></affiliation></author><author><name sortKey="Brauch, Hiltrud" sort="Brauch, Hiltrud" uniqKey="Brauch H" first="Hiltrud" last="Brauch">Hiltrud Brauch</name><affiliation><nlm:aff id="A16">Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A17">University of Tübingen, Tübingen, Germany</nlm:aff></affiliation></author><author><name sortKey="Chang Claude, Jenny" sort="Chang Claude, Jenny" uniqKey="Chang Claude J" first="Jenny" last="Chang-Claude">Jenny Chang-Claude</name><affiliation><nlm:aff id="A18">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Carpenter, Jane" sort="Carpenter, Jane" uniqKey="Carpenter J" first="Jane" last="Carpenter">Jane Carpenter</name><affiliation><nlm:aff id="A19">Australian Breast Cancer Tissue Bank, University of Sydney at the Westmead Millennium Institute, Westmead, New South Wales, Australia</nlm:aff></affiliation></author><author><name sortKey="Godwin, Andrew K" sort="Godwin, Andrew K" uniqKey="Godwin A" first="Andrew K" last="Godwin">Andrew K. Godwin</name><affiliation><nlm:aff id="A20">Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA</nlm:aff></affiliation></author><author><name sortKey="Nevanlinna, Heli" sort="Nevanlinna, Heli" uniqKey="Nevanlinna H" first="Heli" last="Nevanlinna">Heli Nevanlinna</name><affiliation><nlm:aff id="A21">Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Giles, Graham G" sort="Giles, Graham G" uniqKey="Giles G" first="Graham G" last="Giles">Graham G. Giles</name><affiliation><nlm:aff id="A22">Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia</nlm:aff></affiliation><affiliation><nlm:aff id="A23">School of Population Health, The University of Melbourne, Melbourne, Victoria, Australia</nlm:aff></affiliation></author><author><name sortKey="Cox, Angela" sort="Cox, Angela" uniqKey="Cox A" first="Angela" last="Cox">Angela Cox</name><affiliation><nlm:aff id="A24">Cancer Research UK/Yorkshire Cancer Research Sheffield Cancer Research Centre, Department of Oncology, University of Sheffield, Sheffield, UK</nlm:aff></affiliation></author><author><name sortKey="Hopper, John L" sort="Hopper, John L" uniqKey="Hopper J" first="John L" last="Hopper">John L. Hopper</name><affiliation><nlm:aff id="A25">Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Victoria, Australia</nlm:aff></affiliation></author><author><name sortKey="Bolla, Manjeet K" sort="Bolla, Manjeet K" uniqKey="Bolla M" first="Manjeet K" last="Bolla">Manjeet K. Bolla</name><affiliation><nlm:aff id="A5">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Wang, Qin" sort="Wang, Qin" uniqKey="Wang Q" first="Qin" last="Wang">Qin Wang</name><affiliation><nlm:aff id="A5">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Dennis, Joe" sort="Dennis, Joe" uniqKey="Dennis J" first="Joe" last="Dennis">Joe Dennis</name><affiliation><nlm:aff id="A5">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Dicks, Ed" sort="Dicks, Ed" uniqKey="Dicks E" first="Ed" last="Dicks">Ed Dicks</name><affiliation><nlm:aff id="A5">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Howat, Will J" sort="Howat, Will J" uniqKey="Howat W" first="Will J" last="Howat">Will J. Howat</name><affiliation><nlm:aff id="A26">Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Schoof, Nils" sort="Schoof, Nils" uniqKey="Schoof N" first="Nils" last="Schoof">Nils Schoof</name><affiliation><nlm:aff id="A27">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</nlm:aff></affiliation></author><author><name sortKey="Bojesen, Stig E" sort="Bojesen, Stig E" uniqKey="Bojesen S" first="Stig E" last="Bojesen">Stig E. Bojesen</name><affiliation><nlm:aff id="A28">Copenhagen General Population Study, Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark</nlm:aff></affiliation></author><author><name sortKey="Lambrechts, Diether" sort="Lambrechts, Diether" uniqKey="Lambrechts D" first="Diether" last="Lambrechts">Diether Lambrechts</name><affiliation><nlm:aff id="A29">Vesalius Research Center (VRC), VIB, Leuven, Belgium</nlm:aff></affiliation><affiliation><nlm:aff id="A30">Department of Oncology, University of Leuven, Leuven, Belgium</nlm:aff></affiliation></author><author><name sortKey="Broeks, Annegien" sort="Broeks, Annegien" uniqKey="Broeks A" first="Annegien" last="Broeks">Annegien Broeks</name><affiliation><nlm:aff id="A6">Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L" last="Andrulis">Irene L. Andrulis</name><affiliation><nlm:aff id="A31">Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada</nlm:aff></affiliation><affiliation><nlm:aff id="A32">Ontario Cancer Genetics Network, Fred A. Litwin Center for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada</nlm:aff></affiliation></author><author><name sortKey="Guenel, Pascal" sort="Guenel, Pascal" uniqKey="Guenel P" first="Pascal" last="Guénel">Pascal Guénel</name><affiliation><nlm:aff id="A33">University Paris–Sud, Unité Mixte de Recherche Scientifique (UMRS) 1018, Villejuif, France</nlm:aff></affiliation><affiliation><nlm:aff id="A34">INSERM (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), Environmental Epidemiology of Cancer, Villejuif, France</nlm:aff></affiliation></author><author><name sortKey="Burwinkel, Barbara" sort="Burwinkel, Barbara" uniqKey="Burwinkel B" first="Barbara" last="Burwinkel">Barbara Burwinkel</name><affiliation><nlm:aff id="A35">Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A36">Molecular Epidemiology Group, DKFZ, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Sawyer, Elinor J" sort="Sawyer, Elinor J" uniqKey="Sawyer E" first="Elinor J" last="Sawyer">Elinor J. Sawyer</name><affiliation><nlm:aff id="A37">Division of Cancer Studies, National Institute for Health Research (NIHR) Comprehensive Biomedical Research Centre, Guy’s & St. Thomas’ National Health Service (NHS) Foundation Trust in partnership with King’s College London, London, UK</nlm:aff></affiliation></author><author><name sortKey="Hollestelle, Antoinette" sort="Hollestelle, Antoinette" uniqKey="Hollestelle A" first="Antoinette" last="Hollestelle">Antoinette Hollestelle</name><affiliation><nlm:aff id="A38">Department of Medical Oncology, Erasmus University Medical Center–Daniel Den Hoed Cancer Center, Rotterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Fletcher, Olivia" sort="Fletcher, Olivia" uniqKey="Fletcher O" first="Olivia" last="Fletcher">Olivia Fletcher</name><affiliation><nlm:aff id="A2">Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK</nlm:aff></affiliation></author><author><name sortKey="Winqvist, Robert" sort="Winqvist, Robert" uniqKey="Winqvist R" first="Robert" last="Winqvist">Robert Winqvist</name><affiliation><nlm:aff id="A39">Laboratory of Cancer Genetics and Tumor Biology, Department of Clinical Genetics, Biocenter Oulu, University of Oulu, Oulu University Hospital, Oulu, Finland</nlm:aff></affiliation></author><author><name sortKey="Brenner, Hermann" sort="Brenner, Hermann" uniqKey="Brenner H" first="Hermann" last="Brenner">Hermann Brenner</name><affiliation><nlm:aff id="A40">Division of Clinical Epidemiology and Aging Research, DKFZ, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Mannermaa, Arto" sort="Mannermaa, Arto" uniqKey="Mannermaa A" first="Arto" last="Mannermaa">Arto Mannermaa</name><affiliation><nlm:aff id="A41">Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland</nlm:aff></affiliation><affiliation><nlm:aff id="A43">Biocenter Kuopio, Cancer Center of Eastern Finland, University of Eastern Finland, Kuopio, Finland</nlm:aff></affiliation></author><author><name sortKey="Hamann, Ute" sort="Hamann, Ute" uniqKey="Hamann U" first="Ute" last="Hamann">Ute Hamann</name><affiliation><nlm:aff id="A44">Molecular Genetics of Breast Cancer, DKFZ, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Meindl, Alfons" sort="Meindl, Alfons" uniqKey="Meindl A" first="Alfons" last="Meindl">Alfons Meindl</name><affiliation><nlm:aff id="A45">Division for Gynaecological Tumor Genetics, Clinic of Gynaecology and Obstetrics, Technische Universität München, Munich, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A46">Division of Gynaecology and Obstetrics, Technische Universität München, Munich, Germany</nlm:aff></affiliation></author><author><name sortKey="Lindblom, Annika" sort="Lindblom, Annika" uniqKey="Lindblom A" first="Annika" last="Lindblom">Annika Lindblom</name><affiliation><nlm:aff id="A47">Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden</nlm:aff></affiliation></author><author><name sortKey="Zheng, Wei" sort="Zheng, Wei" uniqKey="Zheng W" first="Wei" last="Zheng">Wei Zheng</name><affiliation><nlm:aff id="A48">Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA</nlm:aff></affiliation></author><author><name sortKey="Devillee, Peter" sort="Devillee, Peter" uniqKey="Devillee P" first="Peter" last="Devillee">Peter Devillee</name><affiliation><nlm:aff id="A49">Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands</nlm:aff></affiliation><affiliation><nlm:aff id="A50">Department of Pathology, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Goldberg, Mark S" sort="Goldberg, Mark S" uniqKey="Goldberg M" first="Mark S" last="Goldberg">Mark S. Goldberg</name><affiliation><nlm:aff id="A51">Department of Medicine, McGill University, Montreal, Quebec, Canada</nlm:aff></affiliation><affiliation><nlm:aff id="A52">Division of Clinical Epidemiology, McGill University Health Centre, Royal Victoria Hospital, Montreal, Quebec, Canada</nlm:aff></affiliation></author><author><name sortKey="Lubinski, Jan" sort="Lubinski, Jan" uniqKey="Lubinski J" first="Jan" last="Lubinski">Jan Lubinski</name><affiliation><nlm:aff id="A53">Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland</nlm:aff></affiliation></author><author><name sortKey="Kristensen, Vessela" sort="Kristensen, Vessela" uniqKey="Kristensen V" first="Vessela" last="Kristensen">Vessela Kristensen</name><affiliation><nlm:aff id="A54">Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo, Norway</nlm:aff></affiliation><affiliation><nlm:aff id="A55">Faculty of Medicine (Faculty Division Ahus), Universitetet i Oslo, Oslo, Norway</nlm:aff></affiliation></author><author><name sortKey="Swerdlow, Anthony" sort="Swerdlow, Anthony" uniqKey="Swerdlow A" first="Anthony" last="Swerdlow">Anthony Swerdlow</name><affiliation><nlm:aff id="A1">Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, UK</nlm:aff></affiliation></author><author><name sortKey="Anton Culver, Hoda" sort="Anton Culver, Hoda" uniqKey="Anton Culver H" first="Hoda" last="Anton-Culver">Hoda Anton-Culver</name><affiliation><nlm:aff id="A56">Department of Epidemiology, University of California–Irvine, Irvine, California, USA</nlm:aff></affiliation></author><author><name sortKey="Dork, Thilo" sort="Dork, Thilo" uniqKey="Dork T" first="Thilo" last="Dörk">Thilo Dörk</name><affiliation><nlm:aff id="A57">Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany</nlm:aff></affiliation></author><author><name sortKey="Muir, Kenneth" sort="Muir, Kenneth" uniqKey="Muir K" first="Kenneth" last="Muir">Kenneth Muir</name><affiliation><nlm:aff id="A58">Warwick Medical School, Warwick University, Coventry, UK</nlm:aff></affiliation><affiliation><nlm:aff id="A59">Institute of Population Health, University of Manchester, Manchester, UK</nlm:aff></affiliation></author><author><name sortKey="Matsuo, Keitaro" sort="Matsuo, Keitaro" uniqKey="Matsuo K" first="Keitaro" last="Matsuo">Keitaro Matsuo</name><affiliation><nlm:aff id="A60">Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan</nlm:aff></affiliation></author><author><name sortKey="Wu, Anna H" sort="Wu, Anna H" uniqKey="Wu A" first="Anna H" last="Wu">Anna H. Wu</name><affiliation><nlm:aff id="A7">Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA</nlm:aff></affiliation></author><author><name sortKey="Radice, Paolo" sort="Radice, Paolo" uniqKey="Radice P" first="Paolo" last="Radice">Paolo Radice</name><affiliation><nlm:aff id="A61">Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy</nlm:aff></affiliation><affiliation><nlm:aff id="A62">IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy</nlm:aff></affiliation></author><author><name sortKey="Teo, Soo Hwang" sort="Teo, Soo Hwang" uniqKey="Teo S" first="Soo Hwang" last="Teo">Soo Hwang Teo</name><affiliation><nlm:aff id="A63">Cancer Research Initiatives Foundation, Sime Darby Medical Centre, Subang Jaya, University Malaya Cancer Research Institute, University Malaya, Kuala Lumpur, Malaysia</nlm:aff></affiliation><affiliation><nlm:aff id="A64">Breast Cancer Research Unit, University Malaya Cancer Research Institute, University Malaya, Kuala Lumpur, Malaysia</nlm:aff></affiliation></author><author><name sortKey="Shu, Xiao Ou" sort="Shu, Xiao Ou" uniqKey="Shu X" first="Xiao-Ou" last="Shu">Xiao-Ou Shu</name><affiliation><nlm:aff id="A48">Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA</nlm:aff></affiliation></author><author><name sortKey="Blot, William" sort="Blot, William" uniqKey="Blot W" first="William" last="Blot">William Blot</name><affiliation><nlm:aff id="A48">Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A65">International Epidemiology Institute, Rockville, Maryland, USA</nlm:aff></affiliation></author><author><name sortKey="Kang, Daehee" sort="Kang, Daehee" uniqKey="Kang D" first="Daehee" last="Kang">Daehee Kang</name><affiliation><nlm:aff id="A66">Seoul National University College of Medicine, Seoul, Korea</nlm:aff></affiliation></author><author><name sortKey="Hartman, Mikael" sort="Hartman, Mikael" uniqKey="Hartman M" first="Mikael" last="Hartman">Mikael Hartman</name><affiliation><nlm:aff id="A67">Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore</nlm:aff></affiliation><affiliation><nlm:aff id="A68">Saw Swee Hock School of Public Health, National University of Singapore, Singapore</nlm:aff></affiliation></author><author><name sortKey="Sangrajrang, Suleeporn" sort="Sangrajrang, Suleeporn" uniqKey="Sangrajrang S" first="Suleeporn" last="Sangrajrang">Suleeporn Sangrajrang</name><affiliation><nlm:aff id="A69">National Cancer Institute, Bangkok, Thailand</nlm:aff></affiliation></author><author><name sortKey="Shen, Chen Yang" sort="Shen, Chen Yang" uniqKey="Shen C" first="Chen-Yang" last="Shen">Chen-Yang Shen</name><affiliation><nlm:aff id="A70">Colleague of Public Health, China Medical University, Taichong, Taiwan</nlm:aff></affiliation><affiliation><nlm:aff id="A71">Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan</nlm:aff></affiliation></author><author><name sortKey="Southey, Melissa C" sort="Southey, Melissa C" uniqKey="Southey M" first="Melissa C" last="Southey">Melissa C. Southey</name><affiliation><nlm:aff id="A72">Department of Pathology, The University of Melbourne, Melbourne, Victoria, Australia</nlm:aff></affiliation></author><author><name sortKey="Park, Daniel J" sort="Park, Daniel J" uniqKey="Park D" first="Daniel J" last="Park">Daniel J. Park</name><affiliation><nlm:aff id="A72">Department of Pathology, The University of Melbourne, Melbourne, Victoria, Australia</nlm:aff></affiliation></author><author><name sortKey="Hammet, Fleur" sort="Hammet, Fleur" uniqKey="Hammet F" first="Fleur" last="Hammet">Fleur Hammet</name><affiliation><nlm:aff id="A72">Department of Pathology, The University of Melbourne, Melbourne, Victoria, Australia</nlm:aff></affiliation></author><author><name sortKey="Stone, Jennifer" sort="Stone, Jennifer" uniqKey="Stone J" first="Jennifer" last="Stone">Jennifer Stone</name><affiliation><nlm:aff id="A25">Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Victoria, Australia</nlm:aff></affiliation></author><author><name sortKey="Veer, Laura J Van" sort="Veer, Laura J Van" uniqKey="Veer L" first="Laura J Van" last="Veer">Laura J Van Veer</name><affiliation><nlm:aff id="A6">Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Rutgers, Emiel J" sort="Rutgers, Emiel J" uniqKey="Rutgers E" first="Emiel J" last="Rutgers">Emiel J. Rutgers</name><affiliation><nlm:aff id="A6">Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Lophatananon, Artitaya" sort="Lophatananon, Artitaya" uniqKey="Lophatananon A" first="Artitaya" last="Lophatananon">Artitaya Lophatananon</name><affiliation><nlm:aff id="A58">Warwick Medical School, Warwick University, Coventry, UK</nlm:aff></affiliation></author><author><name sortKey="Stewart Brown, Sarah" sort="Stewart Brown, Sarah" uniqKey="Stewart Brown S" first="Sarah" last="Stewart-Brown">Sarah Stewart-Brown</name><affiliation><nlm:aff id="A58">Warwick Medical School, Warwick University, Coventry, UK</nlm:aff></affiliation></author><author><name sortKey="Siriwanarangsan, Pornthep" sort="Siriwanarangsan, Pornthep" uniqKey="Siriwanarangsan P" first="Pornthep" last="Siriwanarangsan">Pornthep Siriwanarangsan</name><affiliation><nlm:aff id="A73">Ministry of Public Health, Bangkok, Thailand</nlm:aff></affiliation></author><author><name sortKey="Peto, Julian" sort="Peto, Julian" uniqKey="Peto J" first="Julian" last="Peto">Julian Peto</name><affiliation><nlm:aff id="A74">Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine, London, UK</nlm:aff></affiliation></author><author><name sortKey="Schrauder, Michael G" sort="Schrauder, Michael G" uniqKey="Schrauder M" first="Michael G" last="Schrauder">Michael G. Schrauder</name><affiliation><nlm:aff id="A14">Department of Gynecology and Obstetrics, University Breast Center Franconia, University Hospital Erlangen, Erlangen, Germany</nlm:aff></affiliation></author><author><name sortKey="Ekici, Arif B" sort="Ekici, Arif B" uniqKey="Ekici A" first="Arif B" last="Ekici">Arif B. Ekici</name><affiliation><nlm:aff id="A75">Institute of Human Genetics, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany</nlm:aff></affiliation></author><author><name sortKey="Beckmann, Matthias W" sort="Beckmann, Matthias W" uniqKey="Beckmann M" first="Matthias W" last="Beckmann">Matthias W. Beckmann</name><affiliation><nlm:aff id="A14">Department of Gynecology and Obstetrics, University Breast Center Franconia, University Hospital Erlangen, Erlangen, Germany</nlm:aff></affiliation></author><author><name sortKey="Silva, Isabel Dos Santos" sort="Silva, Isabel Dos Santos" uniqKey="Silva I" first="Isabel Dos Santos" last="Silva">Isabel Dos Santos Silva</name><affiliation><nlm:aff id="A74">Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine, London, UK</nlm:aff></affiliation></author><author><name sortKey="Johnson, Nichola" sort="Johnson, Nichola" uniqKey="Johnson N" first="Nichola" last="Johnson">Nichola Johnson</name><affiliation><nlm:aff id="A2">Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK</nlm:aff></affiliation></author><author><name sortKey="Warren, Helen" sort="Warren, Helen" uniqKey="Warren H" first="Helen" last="Warren">Helen Warren</name><affiliation><nlm:aff id="A74">Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine, London, UK</nlm:aff></affiliation></author><author><name sortKey="Tomlinson, Ian" sort="Tomlinson, Ian" uniqKey="Tomlinson I" first="Ian" last="Tomlinson">Ian Tomlinson</name><affiliation><nlm:aff id="A76">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff></affiliation><affiliation><nlm:aff id="A77">Oxford Biomedical Research Centre, University of Oxford, Oxford, UK</nlm:aff></affiliation></author><author><name sortKey="Kerin, Michael J" sort="Kerin, Michael J" uniqKey="Kerin M" first="Michael J" last="Kerin">Michael J. Kerin</name><affiliation><nlm:aff id="A78">Department of Surgery, Clinical Science Institute, University Hospital and National University of Ireland, Galway, Ireland</nlm:aff></affiliation></author><author><name sortKey="Miller, Nicola" sort="Miller, Nicola" uniqKey="Miller N" first="Nicola" last="Miller">Nicola Miller</name><affiliation><nlm:aff id="A78">Department of Surgery, Clinical Science Institute, University Hospital and National University of Ireland, Galway, Ireland</nlm:aff></affiliation></author><author><name sortKey="Marme, Federick" sort="Marme, Federick" uniqKey="Marme F" first="Federick" last="Marme">Federick Marme</name><affiliation><nlm:aff id="A35">Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A79">National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Schneeweiss, Andreas" sort="Schneeweiss, Andreas" uniqKey="Schneeweiss A" first="Andreas" last="Schneeweiss">Andreas Schneeweiss</name><affiliation><nlm:aff id="A35">Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A79">National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Sohn, Christof" sort="Sohn, Christof" uniqKey="Sohn C" first="Christof" last="Sohn">Christof Sohn</name><affiliation><nlm:aff id="A35">Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Truong, Therese" sort="Truong, Therese" uniqKey="Truong T" first="Therese" last="Truong">Therese Truong</name><affiliation><nlm:aff id="A33">University Paris–Sud, Unité Mixte de Recherche Scientifique (UMRS) 1018, Villejuif, France</nlm:aff></affiliation><affiliation><nlm:aff id="A34">INSERM (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), Environmental Epidemiology of Cancer, Villejuif, France</nlm:aff></affiliation></author><author><name sortKey="Laurent Puig, Pierre" sort="Laurent Puig, Pierre" uniqKey="Laurent Puig P" first="Pierre" last="Laurent-Puig">Pierre Laurent-Puig</name><affiliation><nlm:aff id="A80">INSERM, Université Paris Sorbonne Cité, UMRS 775, Paris, France</nlm:aff></affiliation></author><author><name sortKey="Kerbrat, Pierre" sort="Kerbrat, Pierre" uniqKey="Kerbrat P" first="Pierre" last="Kerbrat">Pierre Kerbrat</name><affiliation><nlm:aff id="A81">Centre Eugène Marquis, Department of Medical Oncology, Rennes, France</nlm:aff></affiliation></author><author><name sortKey="Nordestgaard, B Rge G" sort="Nordestgaard, B Rge G" uniqKey="Nordestgaard B" first="B Rge G" last="Nordestgaard">B Rge G. Nordestgaard</name><affiliation><nlm:aff id="A28">Copenhagen General Population Study, Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark</nlm:aff></affiliation></author><author><name sortKey="Nielsen, Sune F" sort="Nielsen, Sune F" uniqKey="Nielsen S" first="Sune F" last="Nielsen">Sune F. Nielsen</name><affiliation><nlm:aff id="A28">Copenhagen General Population Study, Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark</nlm:aff></affiliation></author><author><name sortKey="Flyger, Henrik" sort="Flyger, Henrik" uniqKey="Flyger H" first="Henrik" last="Flyger">Henrik Flyger</name><affiliation><nlm:aff id="A82">Department of Breast Surgery, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Denmark</nlm:aff></affiliation></author><author><name sortKey="Milne, Roger L" sort="Milne, Roger L" uniqKey="Milne R" first="Roger L" last="Milne">Roger L. Milne</name><affiliation><nlm:aff id="A83">Genetic & Molecular Epidemiology Group, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), Madrid, Spain</nlm:aff></affiliation></author><author><name sortKey="Perez, Jose Ignacio Arias" sort="Perez, Jose Ignacio Arias" uniqKey="Perez J" first="Jose Ignacio Arias" last="Perez">Jose Ignacio Arias Perez</name><affiliation><nlm:aff id="A84">Servicio de Cirugía General y Especialidades, Hospital Monte Naranco, Oviedo, Spain</nlm:aff></affiliation></author><author><name sortKey="Menendez, Primitiva" sort="Menendez, Primitiva" uniqKey="Menendez P" first="Primitiva" last="Menéndez">Primitiva Menéndez</name><affiliation><nlm:aff id="A85">Servicio de Anatomía Patológica, Hospital Monte Naranco, Oviedo, Spain</nlm:aff></affiliation></author><author><name sortKey="Muller, Heiko" sort="Muller, Heiko" uniqKey="Muller H" first="Heiko" last="Müller">Heiko Müller</name><affiliation><nlm:aff id="A40">Division of Clinical Epidemiology and Aging Research, DKFZ, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Arndt, Volker" sort="Arndt, Volker" uniqKey="Arndt V" first="Volker" last="Arndt">Volker Arndt</name><affiliation><nlm:aff id="A40">Division of Clinical Epidemiology and Aging Research, DKFZ, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Stegmaier, Christa" sort="Stegmaier, Christa" uniqKey="Stegmaier C" first="Christa" last="Stegmaier">Christa Stegmaier</name><affiliation><nlm:aff id="A86">Saarland Cancer Registry, Saarbrücken, Germany</nlm:aff></affiliation></author><author><name sortKey="Lichtner, Peter" sort="Lichtner, Peter" uniqKey="Lichtner P" first="Peter" last="Lichtner">Peter Lichtner</name><affiliation><nlm:aff id="A87">Institute of Human Genetics, Technische Universität München, Munich, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A88">Institute of Human Genetics, Helmholtz Zentrum München–German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Lochmann, Magdalena" sort="Lochmann, Magdalena" uniqKey="Lochmann M" first="Magdalena" last="Lochmann">Magdalena Lochmann</name><affiliation><nlm:aff id="A46">Division of Gynaecology and Obstetrics, Technische Universität München, Munich, Germany</nlm:aff></affiliation></author><author><name sortKey="Justenhoven, Christina" sort="Justenhoven, Christina" uniqKey="Justenhoven C" first="Christina" last="Justenhoven">Christina Justenhoven</name><affiliation><nlm:aff id="A16">Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A17">University of Tübingen, Tübingen, Germany</nlm:aff></affiliation></author><author><name sortKey="Ko, Yon Dschun" sort="Ko, Yon Dschun" uniqKey="Ko Y" first="Yon-Dschun" last="Ko">Yon-Dschun Ko</name><affiliation><nlm:aff id="A89">Department of Internal Medicine, Evangelische Kliniken Bonn, Johanniter Krankenhaus, Bonn, Germany</nlm:aff></affiliation></author><author><name sortKey="Muranen, Taru A" sort="Muranen, Taru A" uniqKey="Muranen T" first="Taru A" last="Muranen">Taru A. Muranen</name><affiliation><nlm:aff id="A21">Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Aittom Ki, Kristiina" sort="Aittom Ki, Kristiina" uniqKey="Aittom Ki K" first="Kristiina" last="Aittom Ki">Kristiina Aittom Ki</name><affiliation><nlm:aff id="A91">Department of Clinical Genetics, Helsinki University Central Hospital, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Blomqvist, Carl" sort="Blomqvist, Carl" uniqKey="Blomqvist C" first="Carl" last="Blomqvist">Carl Blomqvist</name><affiliation><nlm:aff id="A92">Department of Oncology, Helsinki University Central Hospital, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Greco, Dario" sort="Greco, Dario" uniqKey="Greco D" first="Dario" last="Greco">Dario Greco</name><affiliation><nlm:aff id="A21">Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Heikkinen, Tuomas" sort="Heikkinen, Tuomas" uniqKey="Heikkinen T" first="Tuomas" last="Heikkinen">Tuomas Heikkinen</name><affiliation><nlm:aff id="A21">Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Ito, Hidemi" sort="Ito, Hidemi" uniqKey="Ito H" first="Hidemi" last="Ito">Hidemi Ito</name><affiliation><nlm:aff id="A60">Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan</nlm:aff></affiliation></author><author><name sortKey="Iwata, Hiroji" sort="Iwata, Hiroji" uniqKey="Iwata H" first="Hiroji" last="Iwata">Hiroji Iwata</name><affiliation><nlm:aff id="A93">Department of Breast Oncology, Aichi Cancer Center Hospital, Nagoya, Japan</nlm:aff></affiliation></author><author><name sortKey="Yatabe, Yasushi" sort="Yatabe, Yasushi" uniqKey="Yatabe Y" first="Yasushi" last="Yatabe">Yasushi Yatabe</name><affiliation><nlm:aff id="A94">Department of Pathology and Molecular Diagnostics, Aichi Cancer Center Hospital, Nagoya, Japan</nlm:aff></affiliation></author><author><name sortKey="Antonenkova, Natalia N" sort="Antonenkova, Natalia N" uniqKey="Antonenkova N" first="Natalia N" last="Antonenkova">Natalia N. Antonenkova</name><affiliation><nlm:aff id="A95">N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus</nlm:aff></affiliation></author><author><name sortKey="Margolin, Sara" sort="Margolin, Sara" uniqKey="Margolin S" first="Sara" last="Margolin">Sara Margolin</name><affiliation><nlm:aff id="A96">Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden</nlm:aff></affiliation></author><author><name sortKey="Kataja, Vesa" sort="Kataja, Vesa" uniqKey="Kataja V" first="Vesa" last="Kataja">Vesa Kataja</name><affiliation><nlm:aff id="A42">School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, Kuopio, Finland</nlm:aff></affiliation><affiliation><nlm:aff id="A43">Biocenter Kuopio, Cancer Center of Eastern Finland, University of Eastern Finland, Kuopio, Finland</nlm:aff></affiliation><affiliation><nlm:aff id="A97">Cancer Center, Kuopio University Hospital, Kuopio, Finland</nlm:aff></affiliation></author><author><name sortKey="Kosma, Veli Matti" sort="Kosma, Veli Matti" uniqKey="Kosma V" first="Veli-Matti" last="Kosma">Veli-Matti Kosma</name><affiliation><nlm:aff id="A41">Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland</nlm:aff></affiliation><affiliation><nlm:aff id="A43">Biocenter Kuopio, Cancer Center of Eastern Finland, University of Eastern Finland, Kuopio, Finland</nlm:aff></affiliation></author><author><name sortKey="Hartikainen, Jaana M" sort="Hartikainen, Jaana M" uniqKey="Hartikainen J" first="Jaana M" last="Hartikainen">Jaana M. Hartikainen</name><affiliation><nlm:aff id="A41">Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland</nlm:aff></affiliation><affiliation><nlm:aff id="A43">Biocenter Kuopio, Cancer Center of Eastern Finland, University of Eastern Finland, Kuopio, Finland</nlm:aff></affiliation></author><author><name sortKey="Balleine, Rosemary" sort="Balleine, Rosemary" uniqKey="Balleine R" first="Rosemary" last="Balleine">Rosemary Balleine</name><affiliation><nlm:aff id="A98">Western Sydney Local Health District, Westmead Millennium Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia</nlm:aff></affiliation><affiliation><nlm:aff id="A99">Nepean Blue Mountains Local Health District, Westmead Millennium Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia</nlm:aff></affiliation></author><author><name sortKey="Tseng, Chiu Chen" sort="Tseng, Chiu Chen" uniqKey="Tseng C" first="Chiu-Chen" last="Tseng">Chiu-Chen Tseng</name><affiliation><nlm:aff id="A7">Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA</nlm:aff></affiliation></author><author><name sortKey="Van Den Berg, David" sort="Van Den Berg, David" uniqKey="Van Den Berg D" first="David" last="Van Den Berg">David Van Den Berg</name><affiliation><nlm:aff id="A7">Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA</nlm:aff></affiliation></author><author><name sortKey="Stram, Daniel O" sort="Stram, Daniel O" uniqKey="Stram D" first="Daniel O" last="Stram">Daniel O. Stram</name><affiliation><nlm:aff id="A7">Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA</nlm:aff></affiliation></author><author><name sortKey="Neven, Patrick" sort="Neven, Patrick" uniqKey="Neven P" first="Patrick" last="Neven">Patrick Neven</name><affiliation><nlm:aff id="A100">Multidisciplinary Breast Center, University Hospital Gasthuisberg, Department of Oncology, University of Leuven, Leuven, Belgium</nlm:aff></affiliation></author><author><name sortKey="Dieudonne, Anne Sophie" sort="Dieudonne, Anne Sophie" uniqKey="Dieudonne A" first="Anne-Sophie" last="Dieudonné">Anne-Sophie Dieudonné</name><affiliation><nlm:aff id="A100">Multidisciplinary Breast Center, University Hospital Gasthuisberg, Department of Oncology, University of Leuven, Leuven, Belgium</nlm:aff></affiliation></author><author><name sortKey="Leunen, Karin" sort="Leunen, Karin" uniqKey="Leunen K" first="Karin" last="Leunen">Karin Leunen</name><affiliation><nlm:aff id="A100">Multidisciplinary Breast Center, University Hospital Gasthuisberg, Department of Oncology, University of Leuven, Leuven, Belgium</nlm:aff></affiliation></author><author><name sortKey="Rudolph, Anja" sort="Rudolph, Anja" uniqKey="Rudolph A" first="Anja" last="Rudolph">Anja Rudolph</name><affiliation><nlm:aff id="A18">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Nickels, Stefan" sort="Nickels, Stefan" uniqKey="Nickels S" first="Stefan" last="Nickels">Stefan Nickels</name><affiliation><nlm:aff id="A18">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Flesch Janys, Dieter" sort="Flesch Janys, Dieter" uniqKey="Flesch Janys D" first="Dieter" last="Flesch-Janys">Dieter Flesch-Janys</name><affiliation><nlm:aff id="A101">Department of Cancer Epidemiology/Clinical Cancer Registry, University Clinic Hamburg-Eppendorf, Hamburg, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A102">Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg, Germany</nlm:aff></affiliation></author><author><name sortKey="Peterlongo, Paolo" sort="Peterlongo, Paolo" uniqKey="Peterlongo P" first="Paolo" last="Peterlongo">Paolo Peterlongo</name><affiliation><nlm:aff id="A61">Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy</nlm:aff></affiliation><affiliation><nlm:aff id="A62">IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy</nlm:aff></affiliation></author><author><name sortKey="Peissel, Bernard" sort="Peissel, Bernard" uniqKey="Peissel B" first="Bernard" last="Peissel">Bernard Peissel</name><affiliation><nlm:aff id="A103">Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS INT, Milan, Italy</nlm:aff></affiliation></author><author><name sortKey="Bernard, Loris" sort="Bernard, Loris" uniqKey="Bernard L" first="Loris" last="Bernard">Loris Bernard</name><affiliation><nlm:aff id="A104">Department of Experimental Oncology, Istituto Europeo di Oncologia, Milan, Italy</nlm:aff></affiliation><affiliation><nlm:aff id="A105">Cogentech Cancer Genetic Test Laboratory, Milan, Italy</nlm:aff></affiliation></author><author><name sortKey="Olson, Janet E" sort="Olson, Janet E" uniqKey="Olson J" first="Janet E" last="Olson">Janet E. Olson</name><affiliation><nlm:aff id="A3">Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota, USA</nlm:aff></affiliation></author><author><name sortKey="Wang, Xianshu" sort="Wang, Xianshu" uniqKey="Wang X" first="Xianshu" last="Wang">Xianshu Wang</name><affiliation><nlm:aff id="A3">Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A106">Department of Laboratory Medicine and Pathology, Division of Experimental Pathology, Mayo Clinic, Rochester, Minnesota, USA</nlm:aff></affiliation></author><author><name sortKey="Stevens, Kristen" sort="Stevens, Kristen" uniqKey="Stevens K" first="Kristen" last="Stevens">Kristen Stevens</name><affiliation><nlm:aff id="A3">Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota, USA</nlm:aff></affiliation></author><author><name sortKey="Severi, Gianluca" sort="Severi, Gianluca" uniqKey="Severi G" first="Gianluca" last="Severi">Gianluca Severi</name><affiliation><nlm:aff id="A22">Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia</nlm:aff></affiliation><affiliation><nlm:aff id="A25">Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Victoria, Australia</nlm:aff></affiliation></author><author><name sortKey="Baglietto, Laura" sort="Baglietto, Laura" uniqKey="Baglietto L" first="Laura" last="Baglietto">Laura Baglietto</name><affiliation><nlm:aff id="A22">Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia</nlm:aff></affiliation><affiliation><nlm:aff id="A25">Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Victoria, Australia</nlm:aff></affiliation></author><author><name sortKey="Mclean, Catriona" sort="Mclean, Catriona" uniqKey="Mclean C" first="Catriona" last="Mclean">Catriona Mclean</name><affiliation><nlm:aff id="A107">Department of Anatomical Pathology, The Alfred Hospital, Melbourne, Victoria, Australia</nlm:aff></affiliation></author><author><name sortKey="Coetzee, Gerhard A" sort="Coetzee, Gerhard A" uniqKey="Coetzee G" first="Gerhard A" last="Coetzee">Gerhard A. Coetzee</name><affiliation><nlm:aff id="A7">Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A108">Department of Urology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA</nlm:aff></affiliation></author><author><name sortKey="Feng, Ye" sort="Feng, Ye" uniqKey="Feng Y" first="Ye" last="Feng">Ye Feng</name><affiliation><nlm:aff id="A7">Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA</nlm:aff></affiliation></author><author><name sortKey="Henderson, Brian E" sort="Henderson, Brian E" uniqKey="Henderson B" first="Brian E" last="Henderson">Brian E. Henderson</name><affiliation><nlm:aff id="A7">Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA</nlm:aff></affiliation></author><author><name sortKey="Schumacher, Fredrick" sort="Schumacher, Fredrick" uniqKey="Schumacher F" first="Fredrick" last="Schumacher">Fredrick Schumacher</name><affiliation><nlm:aff id="A7">Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA</nlm:aff></affiliation></author><author><name sortKey="Bogdanova, Natalia V" sort="Bogdanova, Natalia V" uniqKey="Bogdanova N" first="Natalia V" last="Bogdanova">Natalia V. Bogdanova</name><affiliation><nlm:aff id="A57">Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A109">Department of Radiation Oncology, Hannover Medical School, Hannover, Germany</nlm:aff></affiliation></author><author><name sortKey="Labreche, France" sort="Labreche, France" uniqKey="Labreche F" first="France" last="Labrèche">France Labrèche</name><affiliation><nlm:aff id="A110">Département de Médecine Sociale et Préventive, Département de Santé Environnementale et Santé au Travail, Université de Montréal, Montreal, Quebec, Canada</nlm:aff></affiliation></author><author><name sortKey="Dumont, Martine" sort="Dumont, Martine" uniqKey="Dumont M" first="Martine" last="Dumont">Martine Dumont</name><affiliation><nlm:aff id="A111">Cancer Genomics Laboratory, Centre Hospitalier Universitaire de Québec and Laval University, Quebec City, Quebec, Canada</nlm:aff></affiliation></author><author><name sortKey="Yip, Cheng Har" sort="Yip, Cheng Har" uniqKey="Yip C" first="Cheng Har" last="Yip">Cheng Har Yip</name><affiliation><nlm:aff id="A64">Breast Cancer Research Unit, University Malaya Cancer Research Institute, University Malaya, Kuala Lumpur, Malaysia</nlm:aff></affiliation></author><author><name sortKey="Taib, Nur Aishah Mohd" sort="Taib, Nur Aishah Mohd" uniqKey="Taib N" first="Nur Aishah Mohd" last="Taib">Nur Aishah Mohd Taib</name><affiliation><nlm:aff id="A64">Breast Cancer Research Unit, University Malaya Cancer Research Institute, University Malaya, Kuala Lumpur, Malaysia</nlm:aff></affiliation></author><author><name sortKey="Cheng, Ching Yu" sort="Cheng, Ching Yu" uniqKey="Cheng C" first="Ching-Yu" last="Cheng">Ching-Yu Cheng</name><affiliation><nlm:aff id="A67">Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore</nlm:aff></affiliation><affiliation><nlm:aff id="A68">Saw Swee Hock School of Public Health, National University of Singapore, Singapore</nlm:aff></affiliation><affiliation><nlm:aff id="A112">Singapore Eye Research Institute, National University of Singapore, Singapore</nlm:aff></affiliation></author><author><name sortKey="Shrubsole, Martha" sort="Shrubsole, Martha" uniqKey="Shrubsole M" first="Martha" last="Shrubsole">Martha Shrubsole</name><affiliation><nlm:aff id="A48">Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA</nlm:aff></affiliation></author><author><name sortKey="Long, Jirong" sort="Long, Jirong" uniqKey="Long J" first="Jirong" last="Long">Jirong Long</name><affiliation><nlm:aff id="A48">Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA</nlm:aff></affiliation></author><author><name sortKey="Pylk S, Katri" sort="Pylk S, Katri" uniqKey="Pylk S K" first="Katri" last="Pylk S">Katri Pylk S</name><affiliation><nlm:aff id="A39">Laboratory of Cancer Genetics and Tumor Biology, Department of Clinical Genetics, Biocenter Oulu, University of Oulu, Oulu University Hospital, Oulu, Finland</nlm:aff></affiliation></author><author><name sortKey="Jukkola Vuorinen, Arja" sort="Jukkola Vuorinen, Arja" uniqKey="Jukkola Vuorinen A" first="Arja" last="Jukkola-Vuorinen">Arja Jukkola-Vuorinen</name><affiliation><nlm:aff id="A113">Department of Oncology, Oulu University Hospital, University of Oulu, Oulu, Finland</nlm:aff></affiliation></author><author><name sortKey="Kauppila, Saila" sort="Kauppila, Saila" uniqKey="Kauppila S" first="Saila" last="Kauppila">Saila Kauppila</name><affiliation><nlm:aff id="A114">Department of Pathology, Oulu University Hospital, University of Oulu, Oulu, Finland</nlm:aff></affiliation></author><author><name sortKey="Knight, Julia A" sort="Knight, Julia A" uniqKey="Knight J" first="Julia A" last="Knight">Julia A. Knight</name><affiliation><nlm:aff id="A32">Ontario Cancer Genetics Network, Fred A. Litwin Center for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada</nlm:aff></affiliation><affiliation><nlm:aff id="A115">Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada</nlm:aff></affiliation><affiliation><nlm:aff id="A116">Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada</nlm:aff></affiliation></author><author><name sortKey="Glendon, Gord" sort="Glendon, Gord" uniqKey="Glendon G" first="Gord" last="Glendon">Gord Glendon</name><affiliation><nlm:aff id="A32">Ontario Cancer Genetics Network, Fred A. Litwin Center for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada</nlm:aff></affiliation></author><author><name sortKey="Mulligan, Anna Marie" sort="Mulligan, Anna Marie" uniqKey="Mulligan A" first="Anna Marie" last="Mulligan">Anna Marie Mulligan</name><affiliation><nlm:aff id="A117">Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada</nlm:aff></affiliation><affiliation><nlm:aff id="A118">Department of Laboratory Medicine, Keenan Research Centre of the Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, Ontario, Canada</nlm:aff></affiliation></author><author><name sortKey="Tollenaar, Robertus A E M" sort="Tollenaar, Robertus A E M" uniqKey="Tollenaar R" first="Robertus A E M" last="Tollenaar">Robertus A E M. Tollenaar</name><affiliation><nlm:aff id="A119">Department of Surgical Oncology, Leiden University Medical Center, Leiden, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Seynaeve, Caroline M" sort="Seynaeve, Caroline M" uniqKey="Seynaeve C" first="Caroline M" last="Seynaeve">Caroline M. Seynaeve</name><affiliation><nlm:aff id="A38">Department of Medical Oncology, Erasmus University Medical Center–Daniel Den Hoed Cancer Center, Rotterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Kriege, Mieke" sort="Kriege, Mieke" uniqKey="Kriege M" first="Mieke" last="Kriege">Mieke Kriege</name><affiliation><nlm:aff id="A38">Department of Medical Oncology, Erasmus University Medical Center–Daniel Den Hoed Cancer Center, Rotterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Hooning, Maartje J" sort="Hooning, Maartje J" uniqKey="Hooning M" first="Maartje J" last="Hooning">Maartje J. Hooning</name><affiliation><nlm:aff id="A38">Department of Medical Oncology, Erasmus University Medical Center–Daniel Den Hoed Cancer Center, Rotterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Van Den Ouweland, Ans M W" sort="Van Den Ouweland, Ans M W" uniqKey="Van Den Ouweland A" first="Ans M W" last="Van Den Ouweland">Ans M W. Van Den Ouweland</name><affiliation><nlm:aff id="A120">Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Van Deurzen, Carolien H M" sort="Van Deurzen, Carolien H M" uniqKey="Van Deurzen C" first="Carolien H M" last="Van Deurzen">Carolien H M. Van Deurzen</name><affiliation><nlm:aff id="A50">Department of Pathology, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Lu, Wei" sort="Lu, Wei" uniqKey="Lu W" first="Wei" last="Lu">Wei Lu</name><affiliation><nlm:aff id="A121">Shanghai Center for Disease Control and Prevention, Shanghai, China</nlm:aff></affiliation></author><author><name sortKey="Gao, Yu Tang" sort="Gao, Yu Tang" uniqKey="Gao Y" first="Yu-Tang" last="Gao">Yu-Tang Gao</name><affiliation><nlm:aff id="A122">Department of Epidemiology, Shanghai Cancer Institute, Shanghai, China</nlm:aff></affiliation></author><author><name sortKey="Cai, Hui" sort="Cai, Hui" uniqKey="Cai H" first="Hui" last="Cai">Hui Cai</name><affiliation><nlm:aff id="A48">Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA</nlm:aff></affiliation></author><author><name sortKey="Balasubramanian, Sabapathy P" sort="Balasubramanian, Sabapathy P" uniqKey="Balasubramanian S" first="Sabapathy P" last="Balasubramanian">Sabapathy P. Balasubramanian</name><affiliation><nlm:aff id="A24">Cancer Research UK/Yorkshire Cancer Research Sheffield Cancer Research Centre, Department of Oncology, University of Sheffield, Sheffield, UK</nlm:aff></affiliation></author><author><name sortKey="Cross, Simon S" sort="Cross, Simon S" uniqKey="Cross S" first="Simon S" last="Cross">Simon S. Cross</name><affiliation><nlm:aff id="A123">Academic Unit of Pathology, Department of Neuroscience, University of Sheffield, Sheffield, UK</nlm:aff></affiliation></author><author><name sortKey="Reed, Malcolm W R" sort="Reed, Malcolm W R" uniqKey="Reed M" first="Malcolm W R" last="Reed">Malcolm W R. Reed</name><affiliation><nlm:aff id="A24">Cancer Research UK/Yorkshire Cancer Research Sheffield Cancer Research Centre, Department of Oncology, University of Sheffield, Sheffield, UK</nlm:aff></affiliation></author><author><name sortKey="Signorello, Lisa" sort="Signorello, Lisa" uniqKey="Signorello L" first="Lisa" last="Signorello">Lisa Signorello</name><affiliation><nlm:aff id="A48">Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA</nlm:aff></affiliation></author><author><name sortKey="Cai, Qiuyin" sort="Cai, Qiuyin" uniqKey="Cai Q" first="Qiuyin" last="Cai">Qiuyin Cai</name><affiliation><nlm:aff id="A52">Division of Clinical Epidemiology, McGill University Health Centre, Royal Victoria Hospital, Montreal, Quebec, Canada</nlm:aff></affiliation></author><author><name sortKey="Shah, Mitul" sort="Shah, Mitul" uniqKey="Shah M" first="Mitul" last="Shah">Mitul Shah</name><affiliation><nlm:aff id="A124">Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Miao, Hui" sort="Miao, Hui" uniqKey="Miao H" first="Hui" last="Miao">Hui Miao</name><affiliation><nlm:aff id="A68">Saw Swee Hock School of Public Health, National University of Singapore, Singapore</nlm:aff></affiliation></author><author><name sortKey="Chan, Ching Wan" sort="Chan, Ching Wan" uniqKey="Chan C" first="Ching Wan" last="Chan">Ching Wan Chan</name><affiliation><nlm:aff id="A125">Department of Surgery, National University Health System, Singapore</nlm:aff></affiliation></author><author><name sortKey="Chia, Kee Seng" sort="Chia, Kee Seng" uniqKey="Chia K" first="Kee Seng" last="Chia">Kee Seng Chia</name><affiliation><nlm:aff id="A68">Saw Swee Hock School of Public Health, National University of Singapore, Singapore</nlm:aff></affiliation></author><author><name sortKey="Jakubowska, Anna" sort="Jakubowska, Anna" uniqKey="Jakubowska A" first="Anna" last="Jakubowska">Anna Jakubowska</name><affiliation><nlm:aff id="A53">Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland</nlm:aff></affiliation></author><author><name sortKey="Jaworska, Katarzyna" sort="Jaworska, Katarzyna" uniqKey="Jaworska K" first="Katarzyna" last="Jaworska">Katarzyna Jaworska</name><affiliation><nlm:aff id="A53">Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland</nlm:aff></affiliation></author><author><name sortKey="Durda, Katarzyna" sort="Durda, Katarzyna" uniqKey="Durda K" first="Katarzyna" last="Durda">Katarzyna Durda</name><affiliation><nlm:aff id="A53">Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland</nlm:aff></affiliation></author><author><name sortKey="Hsiung, Chia Ni" sort="Hsiung, Chia Ni" uniqKey="Hsiung C" first="Chia-Ni" last="Hsiung">Chia-Ni Hsiung</name><affiliation><nlm:aff id="A71">Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan</nlm:aff></affiliation></author><author><name sortKey="Wu, Pei Ei" sort="Wu, Pei Ei" uniqKey="Wu P" first="Pei-Ei" last="Wu">Pei-Ei Wu</name><affiliation><nlm:aff id="A126">Taiwan Biobank, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan</nlm:aff></affiliation></author><author><name sortKey="Yu, Jyh Cherng" sort="Yu, Jyh Cherng" uniqKey="Yu J" first="Jyh-Cherng" last="Yu">Jyh-Cherng Yu</name><affiliation><nlm:aff id="A127">Department of Surgery, Tri-Service General Hospital, Taipei, Taiwan</nlm:aff></affiliation></author><author><name sortKey="Ashworth, Alan" sort="Ashworth, Alan" uniqKey="Ashworth A" first="Alan" last="Ashworth">Alan Ashworth</name><affiliation><nlm:aff id="A2">Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK</nlm:aff></affiliation></author><author><name sortKey="Jones, Michael" sort="Jones, Michael" uniqKey="Jones M" first="Michael" last="Jones">Michael Jones</name><affiliation><nlm:aff id="A1">Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, UK</nlm:aff></affiliation></author><author><name sortKey="Tessier, Daniel C" sort="Tessier, Daniel C" uniqKey="Tessier D" first="Daniel C" last="Tessier">Daniel C. Tessier</name><affiliation><nlm:aff id="A128">McGill University and Génome Québec Innovation Centre, Montreal, Québec, Canada</nlm:aff></affiliation></author><author><name sortKey="Gonzalez Neira, Anna" sort="Gonzalez Neira, Anna" uniqKey="Gonzalez Neira A" first="Anna" last="González-Neira">Anna González-Neira</name><affiliation><nlm:aff id="A129">Human Genotyping Unit–CEGEN, Human Cancer Genetics Programme, CNIO, Madrid, Spain</nlm:aff></affiliation></author><author><name sortKey="Pita, Guillermo" sort="Pita, Guillermo" uniqKey="Pita G" first="Guillermo" last="Pita">Guillermo Pita</name><affiliation><nlm:aff id="A129">Human Genotyping Unit–CEGEN, Human Cancer Genetics Programme, CNIO, Madrid, Spain</nlm:aff></affiliation></author><author><name sortKey="Alonso, M Rosario" sort="Alonso, M Rosario" uniqKey="Alonso M" first="M Rosario" last="Alonso">M Rosario Alonso</name><affiliation><nlm:aff id="A129">Human Genotyping Unit–CEGEN, Human Cancer Genetics Programme, CNIO, Madrid, Spain</nlm:aff></affiliation></author><author><name sortKey="Vincent, Daniel" sort="Vincent, Daniel" uniqKey="Vincent D" first="Daniel" last="Vincent">Daniel Vincent</name><affiliation><nlm:aff id="A128">McGill University and Génome Québec Innovation Centre, Montreal, Québec, Canada</nlm:aff></affiliation></author><author><name sortKey="Bacot, Francois" sort="Bacot, Francois" uniqKey="Bacot F" first="Francois" last="Bacot">Francois Bacot</name><affiliation><nlm:aff id="A128">McGill University and Génome Québec Innovation Centre, Montreal, Québec, Canada</nlm:aff></affiliation></author><author><name sortKey="Ambrosone, Christine B" sort="Ambrosone, Christine B" uniqKey="Ambrosone C" first="Christine B" last="Ambrosone">Christine B. Ambrosone</name><affiliation><nlm:aff id="A130">Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, New York, USA</nlm:aff></affiliation></author><author><name sortKey="Bandera, Elisa V" sort="Bandera, Elisa V" uniqKey="Bandera E" first="Elisa V" last="Bandera">Elisa V. Bandera</name><affiliation><nlm:aff id="A131">The Cancer Institute of New Jersey, New Brunswick, New Jersey, USA</nlm:aff></affiliation></author><author><name sortKey="John, Esther M" sort="John, Esther M" uniqKey="John E" first="Esther M" last="John">Esther M. John</name><affiliation><nlm:aff id="A132">Cancer Prevention Institute of California, Fremont, California, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A133">Department of Health Research and Policy, Division of Epidemiology, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California, USA</nlm:aff></affiliation></author><author><name sortKey="Chen, Gary K" sort="Chen, Gary K" uniqKey="Chen G" first="Gary K" last="Chen">Gary K. Chen</name><affiliation><nlm:aff id="A7">Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA</nlm:aff></affiliation></author><author><name sortKey="Hu, Jennifer J" sort="Hu, Jennifer J" uniqKey="Hu J" first="Jennifer J" last="Hu">Jennifer J. Hu</name><affiliation><nlm:aff id="A134">Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A135">Department of Epidemiology and Public Health, University of Miami Miller School of Medicine, Miami, Florida, USA</nlm:aff></affiliation></author><author><name sortKey="Rodriguez Gil, Jorge L" sort="Rodriguez Gil, Jorge L" uniqKey="Rodriguez Gil J" first="Jorge L" last="Rodriguez-Gil">Jorge L. Rodriguez-Gil</name><affiliation><nlm:aff id="A134">Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A135">Department of Epidemiology and Public Health, University of Miami Miller School of Medicine, Miami, Florida, USA</nlm:aff></affiliation></author><author><name sortKey="Bernstein, Leslie" sort="Bernstein, Leslie" uniqKey="Bernstein L" first="Leslie" last="Bernstein">Leslie Bernstein</name><affiliation><nlm:aff id="A136">Division of Cancer Etiology, Department of Population Science, Beckman Research Institute, City of Hope, Duarte, California, USA</nlm:aff></affiliation></author><author><name sortKey="Press, Michael F" sort="Press, Michael F" uniqKey="Press M" first="Michael F" last="Press">Michael F. Press</name><affiliation><nlm:aff id="A137">Department of Pathology, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA</nlm:aff></affiliation></author><author><name sortKey="Ziegler, Regina G" sort="Ziegler, Regina G" uniqKey="Ziegler R" first="Regina G" last="Ziegler">Regina G. Ziegler</name><affiliation><nlm:aff id="A138">Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA</nlm:aff></affiliation></author><author><name sortKey="Millikan, Robert M" sort="Millikan, Robert M" uniqKey="Millikan R" first="Robert M" last="Millikan">Robert M. Millikan</name><affiliation><nlm:aff id="A139">Department of Epidemiology, Gillings School of Global Public Health, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, Chapel Hill, North Carolina, USA</nlm:aff></affiliation></author><author><name sortKey="Deming Halverson, Sandra L" sort="Deming Halverson, Sandra L" uniqKey="Deming Halverson S" first="Sandra L" last="Deming-Halverson">Sandra L. Deming-Halverson</name><affiliation><nlm:aff id="A48">Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA</nlm:aff></affiliation></author><author><name sortKey="Nyante, Sarah" sort="Nyante, Sarah" uniqKey="Nyante S" first="Sarah" last="Nyante">Sarah Nyante</name><affiliation><nlm:aff id="A139">Department of Epidemiology, Gillings School of Global Public Health, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, Chapel Hill, North Carolina, USA</nlm:aff></affiliation></author><author><name sortKey="Ingles, Sue A" sort="Ingles, Sue A" uniqKey="Ingles S" first="Sue A" last="Ingles">Sue A. Ingles</name><affiliation><nlm:aff id="A7">Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA</nlm:aff></affiliation></author><author><name sortKey="Waisfisz, Quinten" sort="Waisfisz, Quinten" uniqKey="Waisfisz Q" first="Quinten" last="Waisfisz">Quinten Waisfisz</name><affiliation><nlm:aff id="A140">Section of Oncogenetics, Department of Clinical Genetics, VU University Medical Center, Amsterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Tsimiklis, Helen" sort="Tsimiklis, Helen" uniqKey="Tsimiklis H" first="Helen" last="Tsimiklis">Helen Tsimiklis</name><affiliation><nlm:aff id="A141">Genetic Epidemiology Laboratory, Department of Pathology, The University of Melbourne, Melbourne, Victoria, Australia</nlm:aff></affiliation></author><author><name sortKey="Makalic, Enes" sort="Makalic, Enes" uniqKey="Makalic E" first="Enes" last="Makalic">Enes Makalic</name><affiliation><nlm:aff id="A23">School of Population Health, The University of Melbourne, Melbourne, Victoria, Australia</nlm:aff></affiliation><affiliation><nlm:aff id="A25">Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Victoria, Australia</nlm:aff></affiliation></author><author><name sortKey="Schmidt, Daniel" sort="Schmidt, Daniel" uniqKey="Schmidt D" first="Daniel" last="Schmidt">Daniel Schmidt</name><affiliation><nlm:aff id="A23">School of Population Health, The University of Melbourne, Melbourne, Victoria, Australia</nlm:aff></affiliation><affiliation><nlm:aff id="A25">Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Victoria, Australia</nlm:aff></affiliation></author><author><name sortKey="Bui, Minh" sort="Bui, Minh" uniqKey="Bui M" first="Minh" last="Bui">Minh Bui</name><affiliation><nlm:aff id="A23">School of Population Health, The University of Melbourne, Melbourne, Victoria, Australia</nlm:aff></affiliation><affiliation><nlm:aff id="A25">Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Victoria, Australia</nlm:aff></affiliation></author><author><name sortKey="Gibson, Lorna" sort="Gibson, Lorna" uniqKey="Gibson L" first="Lorna" last="Gibson">Lorna Gibson</name><affiliation><nlm:aff id="A74">Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine, London, UK</nlm:aff></affiliation></author><author><name sortKey="Muller Myhsok, Bertram" sort="Muller Myhsok, Bertram" uniqKey="Muller Myhsok B" first="Bertram" last="Müller-Myhsok">Bertram Müller-Myhsok</name><affiliation><nlm:aff id="A142">Statistical Genetics Research Group, Max Planck Institute of Psychiatry, Munich, Germany</nlm:aff></affiliation></author><author><name sortKey="Schmutzler, Rita K" sort="Schmutzler, Rita K" uniqKey="Schmutzler R" first="Rita K" last="Schmutzler">Rita K. Schmutzler</name><affiliation><nlm:aff id="A143">Centre of Hereditary Breast and Ovarian Cancer, University Hospital, Cologne, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A144">Centre of Integrated Oncology, University Hospital, Cologne, Germany</nlm:aff></affiliation></author><author><name sortKey="Hein, Rebecca" sort="Hein, Rebecca" uniqKey="Hein R" first="Rebecca" last="Hein">Rebecca Hein</name><affiliation><nlm:aff id="A18">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A145">PMV (Primärmedizinische Versorgung) Research Group, Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany</nlm:aff></affiliation></author><author><name sortKey="Dahmen, Norbert" sort="Dahmen, Norbert" uniqKey="Dahmen N" first="Norbert" last="Dahmen">Norbert Dahmen</name><affiliation><nlm:aff id="A146">Department of Psychiatry, University of Mainz, Mainz, Germany</nlm:aff></affiliation></author><author><name sortKey="Beckmann, Lars" sort="Beckmann, Lars" uniqKey="Beckmann L" first="Lars" last="Beckmann">Lars Beckmann</name><affiliation><nlm:aff id="A147">Institute for Quality and Efficiency in Health Care (IQWiG), Cologne, Germany</nlm:aff></affiliation></author><author><name sortKey="Aaltonen, Kirsimari" sort="Aaltonen, Kirsimari" uniqKey="Aaltonen K" first="Kirsimari" last="Aaltonen">Kirsimari Aaltonen</name><affiliation><nlm:aff id="A21">Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland</nlm:aff></affiliation><affiliation><nlm:aff id="A91">Department of Clinical Genetics, Helsinki University Central Hospital, Helsinki, Finland</nlm:aff></affiliation><affiliation><nlm:aff id="A92">Department of Oncology, Helsinki University Central Hospital, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Czene, Kamila" sort="Czene, Kamila" uniqKey="Czene K" first="Kamila" last="Czene">Kamila Czene</name><affiliation><nlm:aff id="A27">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</nlm:aff></affiliation></author><author><name sortKey="Irwanto, Astrid" sort="Irwanto, Astrid" uniqKey="Irwanto A" first="Astrid" last="Irwanto">Astrid Irwanto</name><affiliation><nlm:aff id="A148">Human Genetics Division, Genome Institute of Singapore, Singapore</nlm:aff></affiliation></author><author><name sortKey="Liu, Jianjun" sort="Liu, Jianjun" uniqKey="Liu J" first="Jianjun" last="Liu">Jianjun Liu</name><affiliation><nlm:aff id="A148">Human Genetics Division, Genome Institute of Singapore, Singapore</nlm:aff></affiliation></author><author><name sortKey="Turnbull, Clare" sort="Turnbull, Clare" uniqKey="Turnbull C" first="Clare" last="Turnbull">Clare Turnbull</name><affiliation><nlm:aff id="A1">Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, UK</nlm:aff></affiliation></author><author><name sortKey="Rahman, Nazneen" sort="Rahman, Nazneen" uniqKey="Rahman N" first="Nazneen" last="Rahman">Nazneen Rahman</name><affiliation><nlm:aff id="A1">Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, UK</nlm:aff></affiliation></author><author><name sortKey="Meijers Heijboer, Hanne" sort="Meijers Heijboer, Hanne" uniqKey="Meijers Heijboer H" first="Hanne" last="Meijers-Heijboer">Hanne Meijers-Heijboer</name><affiliation><nlm:aff id="A140">Section of Oncogenetics, Department of Clinical Genetics, VU University Medical Center, Amsterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="Andre G" last="Uitterlinden">Andre G. Uitterlinden</name><affiliation><nlm:aff id="A149">Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Rivadeneira, Fernando" sort="Rivadeneira, Fernando" uniqKey="Rivadeneira F" first="Fernando" last="Rivadeneira">Fernando Rivadeneira</name><affiliation><nlm:aff id="A149">Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Olswold, Curtis" sort="Olswold, Curtis" uniqKey="Olswold C" first="Curtis" last="Olswold">Curtis Olswold</name><affiliation><nlm:aff id="A3">Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota, USA</nlm:aff></affiliation></author><author><name sortKey="Slager, Susan" sort="Slager, Susan" uniqKey="Slager S" first="Susan" last="Slager">Susan Slager</name><affiliation><nlm:aff id="A3">Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota, USA</nlm:aff></affiliation></author><author><name sortKey="Pilarski, Robert" sort="Pilarski, Robert" uniqKey="Pilarski R" first="Robert" last="Pilarski">Robert Pilarski</name><affiliation><nlm:aff id="A150">Department of Internal Medicine, James Comprehensive Cancer Center, Ohio State University, Columbus, Ohio, USA</nlm:aff></affiliation></author><author><name sortKey="Ademuyiwa, Foluso" sort="Ademuyiwa, Foluso" uniqKey="Ademuyiwa F" first="Foluso" last="Ademuyiwa">Foluso Ademuyiwa</name><affiliation><nlm:aff id="A151">Roswell Park Cancer Institute, Buffalo, New York, USA</nlm:aff></affiliation></author><author><name sortKey="Konstantopoulou, Irene" sort="Konstantopoulou, Irene" uniqKey="Konstantopoulou I" first="Irene" last="Konstantopoulou">Irene Konstantopoulou</name><affiliation><nlm:aff id="A152">Molecular Diagnostics Laboratory, Institute of Radioisotopes and Radiodiagnostic Products (IRRP), National Centre for Scientific Research Demokritos, Aghia Paraskevi Attikis, Athens, Greece</nlm:aff></affiliation></author><author><name sortKey="Martin, Nicholas G" sort="Martin, Nicholas G" uniqKey="Martin N" first="Nicholas G" last="Martin">Nicholas G. Martin</name><affiliation><nlm:aff id="A153">QIMR GWAS Collective, Queensland Institute of Medical Research, Brisbane, Queensland, Australia</nlm:aff></affiliation></author><author><name sortKey="Montgomery, Grant W" sort="Montgomery, Grant W" uniqKey="Montgomery G" first="Grant W" last="Montgomery">Grant W. Montgomery</name><affiliation><nlm:aff id="A153">QIMR GWAS Collective, Queensland Institute of Medical Research, Brisbane, Queensland, Australia</nlm:aff></affiliation></author><author><name sortKey="Slamon, Dennis J" sort="Slamon, Dennis J" uniqKey="Slamon D" first="Dennis J" last="Slamon">Dennis J. Slamon</name><affiliation><nlm:aff id="A15">Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A154">Department of Medicine, Division of Hematology and Oncology, University of California, Los Angeles, Los Angeles, California, USA</nlm:aff></affiliation></author><author><name sortKey="Rauh, Claudia" sort="Rauh, Claudia" uniqKey="Rauh C" first="Claudia" last="Rauh">Claudia Rauh</name><affiliation><nlm:aff id="A14">Department of Gynecology and Obstetrics, University Breast Center Franconia, University Hospital Erlangen, Erlangen, Germany</nlm:aff></affiliation></author><author><name sortKey="Lux, Michael P" sort="Lux, Michael P" uniqKey="Lux M" first="Michael P" last="Lux">Michael P. Lux</name><affiliation><nlm:aff id="A14">Department of Gynecology and Obstetrics, University Breast Center Franconia, University Hospital Erlangen, Erlangen, Germany</nlm:aff></affiliation></author><author><name sortKey="Jud, Sebastian M" sort="Jud, Sebastian M" uniqKey="Jud S" first="Sebastian M" last="Jud">Sebastian M. Jud</name><affiliation><nlm:aff id="A14">Department of Gynecology and Obstetrics, University Breast Center Franconia, University Hospital Erlangen, Erlangen, Germany</nlm:aff></affiliation></author><author><name sortKey="Bruning, Thomas" sort="Bruning, Thomas" uniqKey="Bruning T" first="Thomas" last="Bruning">Thomas Bruning</name><affiliation><nlm:aff id="A155">Institute for Prevention and Occupational Medicine of the German Social Accident Insurance (IPA), Bochum, Germany</nlm:aff></affiliation></author><author><name sortKey="Weaver, Joellen" sort="Weaver, Joellen" uniqKey="Weaver J" first="Joellen" last="Weaver">Joellen Weaver</name><affiliation><nlm:aff id="A156">Biosample Repository, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA</nlm:aff></affiliation></author><author><name sortKey="Sharma, Priyanka" sort="Sharma, Priyanka" uniqKey="Sharma P" first="Priyanka" last="Sharma">Priyanka Sharma</name><affiliation><nlm:aff id="A157">Division of Hematology and Oncology, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA</nlm:aff></affiliation></author><author><name sortKey="Pathak, Harsh" sort="Pathak, Harsh" uniqKey="Pathak H" first="Harsh" last="Pathak">Harsh Pathak</name><affiliation><nlm:aff id="A20">Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA</nlm:aff></affiliation></author><author><name sortKey="Tapper, Will" sort="Tapper, Will" uniqKey="Tapper W" first="Will" last="Tapper">Will Tapper</name><affiliation><nlm:aff id="A12">Faculty of Medicine, University of Southampton, Southampton, UK</nlm:aff></affiliation></author><author><name sortKey="Gerty, Sue" sort="Gerty, Sue" uniqKey="Gerty S" first="Sue" last="Gerty">Sue Gerty</name><affiliation><nlm:aff id="A12">Faculty of Medicine, University of Southampton, Southampton, UK</nlm:aff></affiliation></author><author><name sortKey="Durcan, Lorraine" sort="Durcan, Lorraine" uniqKey="Durcan L" first="Lorraine" last="Durcan">Lorraine Durcan</name><affiliation><nlm:aff id="A12">Faculty of Medicine, University of Southampton, Southampton, UK</nlm:aff></affiliation></author><author><name sortKey="Trichopoulos, Dimitrios" sort="Trichopoulos, Dimitrios" uniqKey="Trichopoulos D" first="Dimitrios" last="Trichopoulos">Dimitrios Trichopoulos</name><affiliation><nlm:aff id="A4">Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A158">Bureau of Epidemiologic Research, Academy of Athens, Athens, Greece</nlm:aff></affiliation><affiliation><nlm:aff id="A159">Hellenic Health Foundation, Athens, Greece</nlm:aff></affiliation></author><author><name sortKey="Tumino, Rosario" sort="Tumino, Rosario" uniqKey="Tumino R" first="Rosario" last="Tumino">Rosario Tumino</name><affiliation><nlm:aff id="A160">Cancer Registry, Histopathology Unit Civile MPArezzo Hospital, Ragusa, Italy</nlm:aff></affiliation></author><author><name sortKey="Peeters, Petra H" sort="Peeters, Petra H" uniqKey="Peeters P" first="Petra H" last="Peeters">Petra H. Peeters</name><affiliation><nlm:aff id="A161">Julius Center, University Medical Center Utrecht, Utrecht, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Kaaks, Rudolf" sort="Kaaks, Rudolf" uniqKey="Kaaks R" first="Rudolf" last="Kaaks">Rudolf Kaaks</name><affiliation><nlm:aff id="A18">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Campa, Daniele" sort="Campa, Daniele" uniqKey="Campa D" first="Daniele" last="Campa">Daniele Campa</name><affiliation><nlm:aff id="A18">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Canzian, Federico" sort="Canzian, Federico" uniqKey="Canzian F" first="Federico" last="Canzian">Federico Canzian</name><affiliation><nlm:aff id="A18">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name><affiliation><nlm:aff id="A27">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</nlm:aff></affiliation><affiliation><nlm:aff id="A162">Department of Community Medicine, University of Tromsø, Tromsø, Norway</nlm:aff></affiliation><affiliation><nlm:aff id="A164">Cancer Registry of Norway, Oslo, Norway</nlm:aff></affiliation></author><author><name sortKey="Johansson, Mattias" sort="Johansson, Mattias" uniqKey="Johansson M" first="Mattias" last="Johansson">Mattias Johansson</name><affiliation><nlm:aff id="A165">Genetic Epidemiology Group, International Agency for Research on Cancer, World Health Organization, Lyon, France</nlm:aff></affiliation></author><author><name sortKey="Khaw, Kay Tee" sort="Khaw, Kay Tee" uniqKey="Khaw K" first="Kay-Tee" last="Khaw">Kay-Tee Khaw</name><affiliation><nlm:aff id="A166">Clinical Gerontology Unit, University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Travis, Ruth" sort="Travis, Ruth" uniqKey="Travis R" first="Ruth" last="Travis">Ruth Travis</name><affiliation><nlm:aff id="A167">Cancer Epidemiology Unit, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK</nlm:aff></affiliation></author><author><name sortKey="Clavel Chapelon, Francoise" sort="Clavel Chapelon, Francoise" uniqKey="Clavel Chapelon F" first="Françoise" last="Clavel-Chapelon">Françoise Clavel-Chapelon</name><affiliation><nlm:aff id="A33">University Paris–Sud, Unité Mixte de Recherche Scientifique (UMRS) 1018, Villejuif, France</nlm:aff></affiliation><affiliation><nlm:aff id="A34">INSERM (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), Environmental Epidemiology of Cancer, Villejuif, France</nlm:aff></affiliation></author><author><name sortKey="Kolonel, Laurence N" sort="Kolonel, Laurence N" uniqKey="Kolonel L" first="Laurence N" last="Kolonel">Laurence N. Kolonel</name><affiliation><nlm:aff id="A110">Département de Médecine Sociale et Préventive, Département de Santé Environnementale et Santé au Travail, Université de Montréal, Montreal, Quebec, Canada</nlm:aff></affiliation></author><author><name sortKey="Chen, Constance" sort="Chen, Constance" uniqKey="Chen C" first="Constance" last="Chen">Constance Chen</name><affiliation><nlm:aff id="A4">Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA</nlm:aff></affiliation></author><author><name sortKey="Beck, Andy" sort="Beck, Andy" uniqKey="Beck A" first="Andy" last="Beck">Andy Beck</name><affiliation><nlm:aff id="A168">Department of Pathology, Beth Israel DeaconessMedical Center, Boston, Massachusetts, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A169">Department of Pathology, Harvard Medical School, Boston, Massachusetts, USA</nlm:aff></affiliation></author><author><name sortKey="Hankinson, Susan E" sort="Hankinson, Susan E" uniqKey="Hankinson S" first="Susan E" last="Hankinson">Susan E. Hankinson</name><affiliation><nlm:aff id="A170">Division of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst, Massachusetts, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A171">Channing Division of Network Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, USA</nlm:aff></affiliation></author><author><name sortKey="Berg, Christine D" sort="Berg, Christine D" uniqKey="Berg C" first="Christine D" last="Berg">Christine D. Berg</name><affiliation><nlm:aff id="A172">Division of Cancer Prevention, National Cancer Institute, Bethesda, Maryland, USA</nlm:aff></affiliation></author><author><name sortKey="Hoover, Robert N" sort="Hoover, Robert N" uniqKey="Hoover R" first="Robert N" last="Hoover">Robert N. Hoover</name><affiliation><nlm:aff id="A138">Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA</nlm:aff></affiliation></author><author><name sortKey="Lissowska, Jolanta" sort="Lissowska, Jolanta" uniqKey="Lissowska J" first="Jolanta" last="Lissowska">Jolanta Lissowska</name><affiliation><nlm:aff id="A173">Department of Cancer Epidemiology and Prevention, M Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland</nlm:aff></affiliation></author><author><name sortKey="Figueroa, Jonine D" sort="Figueroa, Jonine D" uniqKey="Figueroa J" first="Jonine D" last="Figueroa">Jonine D. Figueroa</name><affiliation><nlm:aff id="A138">Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA</nlm:aff></affiliation></author><author><name sortKey="Chasman, Daniel I" sort="Chasman, Daniel I" uniqKey="Chasman D" first="Daniel I" last="Chasman">Daniel I. Chasman</name><affiliation><nlm:aff id="A11">Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, USA</nlm:aff></affiliation></author><author><name sortKey="Gaudet, Mia M" sort="Gaudet, Mia M" uniqKey="Gaudet M" first="Mia M" last="Gaudet">Mia M. Gaudet</name><affiliation><nlm:aff id="A174">Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, USA</nlm:aff></affiliation></author><author><name sortKey="Diver, W Ryan" sort="Diver, W Ryan" uniqKey="Diver W" first="W Ryan" last="Diver">W Ryan Diver</name><affiliation><nlm:aff id="A174">Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, USA</nlm:aff></affiliation></author><author><name sortKey="Willett, Walter C" sort="Willett, Walter C" uniqKey="Willett W" first="Walter C" last="Willett">Walter C. Willett</name><affiliation><nlm:aff id="A175">Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA</nlm:aff></affiliation></author><author><name sortKey="Hunter, David J" sort="Hunter, David J" uniqKey="Hunter D" first="David J" last="Hunter">David J. Hunter</name><affiliation><nlm:aff id="A4">Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA</nlm:aff></affiliation></author><author><name sortKey="Simard, Jacques" sort="Simard, Jacques" uniqKey="Simard J" first="Jacques" last="Simard">Jacques Simard</name><affiliation><nlm:aff id="A111">Cancer Genomics Laboratory, Centre Hospitalier Universitaire de Québec and Laval University, Quebec City, Quebec, Canada</nlm:aff></affiliation></author><author><name sortKey="Benitez, Javier" sort="Benitez, Javier" uniqKey="Benitez J" first="Javier" last="Benitez">Javier Benitez</name><affiliation><nlm:aff id="A129">Human Genotyping Unit–CEGEN, Human Cancer Genetics Programme, CNIO, Madrid, Spain</nlm:aff></affiliation><affiliation><nlm:aff id="A176">Human Genetics Group, CNIO, Madrid, Spain</nlm:aff></affiliation><affiliation><nlm:aff id="A177">Centro de Investigacion en Red de Enfermedades Raras (CIBERER), Madrid, Spain</nlm:aff></affiliation></author><author><name sortKey="Dunning, Alison M" sort="Dunning, Alison M" uniqKey="Dunning A" first="Alison M" last="Dunning">Alison M. Dunning</name><affiliation><nlm:aff id="A124">Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Sherman, Mark E" sort="Sherman, Mark E" uniqKey="Sherman M" first="Mark E" last="Sherman">Mark E. Sherman</name><affiliation><nlm:aff id="A138">Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA</nlm:aff></affiliation></author><author><name sortKey="Chenevix Trench, Georgia" sort="Chenevix Trench, Georgia" uniqKey="Chenevix Trench G" first="Georgia" last="Chenevix-Trench">Georgia Chenevix-Trench</name><affiliation><nlm:aff id="A178">Department of Genetics, Queensland Institute of Medical Research, Brisbane, Queensland, Australia</nlm:aff></affiliation></author><author><name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J" last="Chanock">Stephen J. Chanock</name><affiliation><nlm:aff id="A138">Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA</nlm:aff></affiliation></author><author><name sortKey="Hall, Per" sort="Hall, Per" uniqKey="Hall P" first="Per" last="Hall">Per Hall</name><affiliation><nlm:aff id="A27">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</nlm:aff></affiliation></author><author><name sortKey="Pharoah, Paul D P" sort="Pharoah, Paul D P" uniqKey="Pharoah P" first="Paul D P" last="Pharoah">Paul D P. Pharoah</name><affiliation><nlm:aff id="A124">Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Vachon, Celine" sort="Vachon, Celine" uniqKey="Vachon C" first="Celine" last="Vachon">Celine Vachon</name><affiliation><nlm:aff id="A3">Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota, USA</nlm:aff></affiliation></author><author><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F" last="Easton">Douglas F. Easton</name><affiliation><nlm:aff id="A5">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Haiman, Christopher A" sort="Haiman, Christopher A" uniqKey="Haiman C" first="Christopher A" last="Haiman">Christopher A. Haiman</name><affiliation><nlm:aff id="A7">Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA</nlm:aff></affiliation></author><author><name sortKey="Kraft, Peter" sort="Kraft, Peter" uniqKey="Kraft P" first="Peter" last="Kraft">Peter Kraft</name><affiliation><nlm:aff id="A4">Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">23535733</idno><idno type="pmc">3771695</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771695</idno><idno type="RBID">PMC:3771695</idno><idno type="doi">10.1038/ng.2561</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">002142</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002142</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Genome-wide association studies identify four ER negative–specific breast cancer risk loci</title><author><name sortKey="Garcia Closas, Montserrat" sort="Garcia Closas, Montserrat" uniqKey="Garcia Closas M" first="Montserrat" last="Garcia-Closas">Montserrat Garcia-Closas</name><affiliation><nlm:aff id="A1">Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, UK</nlm:aff></affiliation><affiliation><nlm:aff id="A2">Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK</nlm:aff></affiliation></author><author><name sortKey="Couch, Fergus J" sort="Couch, Fergus J" uniqKey="Couch F" first="Fergus J" last="Couch">Fergus J. Couch</name><affiliation><nlm:aff id="A3">Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota, USA</nlm:aff></affiliation></author><author><name sortKey="Lindstrom, Sara" sort="Lindstrom, Sara" uniqKey="Lindstrom S" first="Sara" last="Lindstrom">Sara Lindstrom</name><affiliation><nlm:aff id="A4">Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA</nlm:aff></affiliation></author><author><name sortKey="Michailidou, Kyriaki" sort="Michailidou, Kyriaki" uniqKey="Michailidou K" first="Kyriaki" last="Michailidou">Kyriaki Michailidou</name><affiliation><nlm:aff id="A5">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Schmidt, Marjanka K" sort="Schmidt, Marjanka K" uniqKey="Schmidt M" first="Marjanka K" last="Schmidt">Marjanka K. Schmidt</name><affiliation><nlm:aff id="A6">Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Brook, Mark N" sort="Brook, Mark N" uniqKey="Brook M" first="Mark N" last="Brook">Mark N. Brook</name><affiliation><nlm:aff id="A1">Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, UK</nlm:aff></affiliation></author><author><name sortKey="Orr, Nick" sort="Orr, Nick" uniqKey="Orr N" first="Nick" last="Orr">Nick Orr</name><affiliation><nlm:aff id="A2">Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK</nlm:aff></affiliation></author><author><name sortKey="Rhie, Suhn Kyong" sort="Rhie, Suhn Kyong" uniqKey="Rhie S" first="Suhn Kyong" last="Rhie">Suhn Kyong Rhie</name><affiliation><nlm:aff id="A7">Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA</nlm:aff></affiliation></author><author><name sortKey="Riboli, Elio" sort="Riboli, Elio" uniqKey="Riboli E" first="Elio" last="Riboli">Elio Riboli</name><affiliation><nlm:aff id="A8">School of Public Health, Imperial College, London, UK</nlm:aff></affiliation></author><author><name sortKey="Feigelson, Heather S" sort="Feigelson, Heather S" uniqKey="Feigelson H" first="Heather S" last="Feigelson">Heather S Feigelson</name><affiliation><nlm:aff id="A9">Kaiser Permanente, Institute for Health Research, Denver, Colorado, USA</nlm:aff></affiliation></author><author><name sortKey="Le Marchand, Loic" sort="Le Marchand, Loic" uniqKey="Le Marchand L" first="Loic" last="Le Marchand">Loic Le Marchand</name><affiliation><nlm:aff id="A10">Epidemiology Program, Cancer Research Center, University of Hawaii, Honolulu, Hawaii, USA</nlm:aff></affiliation></author><author><name sortKey="Buring, Julie E" sort="Buring, Julie E" uniqKey="Buring J" first="Julie E" last="Buring">Julie E. Buring</name><affiliation><nlm:aff id="A11">Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, USA</nlm:aff></affiliation></author><author><name sortKey="Eccles, Diana" sort="Eccles, Diana" uniqKey="Eccles D" first="Diana" last="Eccles">Diana Eccles</name><affiliation><nlm:aff id="A12">Faculty of Medicine, University of Southampton, Southampton, UK</nlm:aff></affiliation></author><author><name sortKey="Miron, Penelope" sort="Miron, Penelope" uniqKey="Miron P" first="Penelope" last="Miron">Penelope Miron</name><affiliation><nlm:aff id="A13">Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA</nlm:aff></affiliation></author><author><name sortKey="Fasching, Peter A" sort="Fasching, Peter A" uniqKey="Fasching P" first="Peter A" last="Fasching">Peter A. Fasching</name><affiliation><nlm:aff id="A14">Department of Gynecology and Obstetrics, University Breast Center Franconia, University Hospital Erlangen, Erlangen, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A15">Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA</nlm:aff></affiliation></author><author><name sortKey="Brauch, Hiltrud" sort="Brauch, Hiltrud" uniqKey="Brauch H" first="Hiltrud" last="Brauch">Hiltrud Brauch</name><affiliation><nlm:aff id="A16">Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A17">University of Tübingen, Tübingen, Germany</nlm:aff></affiliation></author><author><name sortKey="Chang Claude, Jenny" sort="Chang Claude, Jenny" uniqKey="Chang Claude J" first="Jenny" last="Chang-Claude">Jenny Chang-Claude</name><affiliation><nlm:aff id="A18">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Carpenter, Jane" sort="Carpenter, Jane" uniqKey="Carpenter J" first="Jane" last="Carpenter">Jane Carpenter</name><affiliation><nlm:aff id="A19">Australian Breast Cancer Tissue Bank, University of Sydney at the Westmead Millennium Institute, Westmead, New South Wales, Australia</nlm:aff></affiliation></author><author><name sortKey="Godwin, Andrew K" sort="Godwin, Andrew K" uniqKey="Godwin A" first="Andrew K" last="Godwin">Andrew K. Godwin</name><affiliation><nlm:aff id="A20">Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA</nlm:aff></affiliation></author><author><name sortKey="Nevanlinna, Heli" sort="Nevanlinna, Heli" uniqKey="Nevanlinna H" first="Heli" last="Nevanlinna">Heli Nevanlinna</name><affiliation><nlm:aff id="A21">Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Giles, Graham G" sort="Giles, Graham G" uniqKey="Giles G" first="Graham G" last="Giles">Graham G. Giles</name><affiliation><nlm:aff id="A22">Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia</nlm:aff></affiliation><affiliation><nlm:aff id="A23">School of Population Health, The University of Melbourne, Melbourne, Victoria, Australia</nlm:aff></affiliation></author><author><name sortKey="Cox, Angela" sort="Cox, Angela" uniqKey="Cox A" first="Angela" last="Cox">Angela Cox</name><affiliation><nlm:aff id="A24">Cancer Research UK/Yorkshire Cancer Research Sheffield Cancer Research Centre, Department of Oncology, University of Sheffield, Sheffield, UK</nlm:aff></affiliation></author><author><name sortKey="Hopper, John L" sort="Hopper, John L" uniqKey="Hopper J" first="John L" last="Hopper">John L. Hopper</name><affiliation><nlm:aff id="A25">Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Victoria, Australia</nlm:aff></affiliation></author><author><name sortKey="Bolla, Manjeet K" sort="Bolla, Manjeet K" uniqKey="Bolla M" first="Manjeet K" last="Bolla">Manjeet K. Bolla</name><affiliation><nlm:aff id="A5">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Wang, Qin" sort="Wang, Qin" uniqKey="Wang Q" first="Qin" last="Wang">Qin Wang</name><affiliation><nlm:aff id="A5">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Dennis, Joe" sort="Dennis, Joe" uniqKey="Dennis J" first="Joe" last="Dennis">Joe Dennis</name><affiliation><nlm:aff id="A5">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Dicks, Ed" sort="Dicks, Ed" uniqKey="Dicks E" first="Ed" last="Dicks">Ed Dicks</name><affiliation><nlm:aff id="A5">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Howat, Will J" sort="Howat, Will J" uniqKey="Howat W" first="Will J" last="Howat">Will J. Howat</name><affiliation><nlm:aff id="A26">Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Schoof, Nils" sort="Schoof, Nils" uniqKey="Schoof N" first="Nils" last="Schoof">Nils Schoof</name><affiliation><nlm:aff id="A27">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</nlm:aff></affiliation></author><author><name sortKey="Bojesen, Stig E" sort="Bojesen, Stig E" uniqKey="Bojesen S" first="Stig E" last="Bojesen">Stig E. Bojesen</name><affiliation><nlm:aff id="A28">Copenhagen General Population Study, Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark</nlm:aff></affiliation></author><author><name sortKey="Lambrechts, Diether" sort="Lambrechts, Diether" uniqKey="Lambrechts D" first="Diether" last="Lambrechts">Diether Lambrechts</name><affiliation><nlm:aff id="A29">Vesalius Research Center (VRC), VIB, Leuven, Belgium</nlm:aff></affiliation><affiliation><nlm:aff id="A30">Department of Oncology, University of Leuven, Leuven, Belgium</nlm:aff></affiliation></author><author><name sortKey="Broeks, Annegien" sort="Broeks, Annegien" uniqKey="Broeks A" first="Annegien" last="Broeks">Annegien Broeks</name><affiliation><nlm:aff id="A6">Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L" last="Andrulis">Irene L. Andrulis</name><affiliation><nlm:aff id="A31">Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada</nlm:aff></affiliation><affiliation><nlm:aff id="A32">Ontario Cancer Genetics Network, Fred A. Litwin Center for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada</nlm:aff></affiliation></author><author><name sortKey="Guenel, Pascal" sort="Guenel, Pascal" uniqKey="Guenel P" first="Pascal" last="Guénel">Pascal Guénel</name><affiliation><nlm:aff id="A33">University Paris–Sud, Unité Mixte de Recherche Scientifique (UMRS) 1018, Villejuif, France</nlm:aff></affiliation><affiliation><nlm:aff id="A34">INSERM (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), Environmental Epidemiology of Cancer, Villejuif, France</nlm:aff></affiliation></author><author><name sortKey="Burwinkel, Barbara" sort="Burwinkel, Barbara" uniqKey="Burwinkel B" first="Barbara" last="Burwinkel">Barbara Burwinkel</name><affiliation><nlm:aff id="A35">Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A36">Molecular Epidemiology Group, DKFZ, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Sawyer, Elinor J" sort="Sawyer, Elinor J" uniqKey="Sawyer E" first="Elinor J" last="Sawyer">Elinor J. Sawyer</name><affiliation><nlm:aff id="A37">Division of Cancer Studies, National Institute for Health Research (NIHR) Comprehensive Biomedical Research Centre, Guy’s & St. Thomas’ National Health Service (NHS) Foundation Trust in partnership with King’s College London, London, UK</nlm:aff></affiliation></author><author><name sortKey="Hollestelle, Antoinette" sort="Hollestelle, Antoinette" uniqKey="Hollestelle A" first="Antoinette" last="Hollestelle">Antoinette Hollestelle</name><affiliation><nlm:aff id="A38">Department of Medical Oncology, Erasmus University Medical Center–Daniel Den Hoed Cancer Center, Rotterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Fletcher, Olivia" sort="Fletcher, Olivia" uniqKey="Fletcher O" first="Olivia" last="Fletcher">Olivia Fletcher</name><affiliation><nlm:aff id="A2">Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK</nlm:aff></affiliation></author><author><name sortKey="Winqvist, Robert" sort="Winqvist, Robert" uniqKey="Winqvist R" first="Robert" last="Winqvist">Robert Winqvist</name><affiliation><nlm:aff id="A39">Laboratory of Cancer Genetics and Tumor Biology, Department of Clinical Genetics, Biocenter Oulu, University of Oulu, Oulu University Hospital, Oulu, Finland</nlm:aff></affiliation></author><author><name sortKey="Brenner, Hermann" sort="Brenner, Hermann" uniqKey="Brenner H" first="Hermann" last="Brenner">Hermann Brenner</name><affiliation><nlm:aff id="A40">Division of Clinical Epidemiology and Aging Research, DKFZ, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Mannermaa, Arto" sort="Mannermaa, Arto" uniqKey="Mannermaa A" first="Arto" last="Mannermaa">Arto Mannermaa</name><affiliation><nlm:aff id="A41">Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland</nlm:aff></affiliation><affiliation><nlm:aff id="A43">Biocenter Kuopio, Cancer Center of Eastern Finland, University of Eastern Finland, Kuopio, Finland</nlm:aff></affiliation></author><author><name sortKey="Hamann, Ute" sort="Hamann, Ute" uniqKey="Hamann U" first="Ute" last="Hamann">Ute Hamann</name><affiliation><nlm:aff id="A44">Molecular Genetics of Breast Cancer, DKFZ, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Meindl, Alfons" sort="Meindl, Alfons" uniqKey="Meindl A" first="Alfons" last="Meindl">Alfons Meindl</name><affiliation><nlm:aff id="A45">Division for Gynaecological Tumor Genetics, Clinic of Gynaecology and Obstetrics, Technische Universität München, Munich, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A46">Division of Gynaecology and Obstetrics, Technische Universität München, Munich, Germany</nlm:aff></affiliation></author><author><name sortKey="Lindblom, Annika" sort="Lindblom, Annika" uniqKey="Lindblom A" first="Annika" last="Lindblom">Annika Lindblom</name><affiliation><nlm:aff id="A47">Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden</nlm:aff></affiliation></author><author><name sortKey="Zheng, Wei" sort="Zheng, Wei" uniqKey="Zheng W" first="Wei" last="Zheng">Wei Zheng</name><affiliation><nlm:aff id="A48">Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA</nlm:aff></affiliation></author><author><name sortKey="Devillee, Peter" sort="Devillee, Peter" uniqKey="Devillee P" first="Peter" last="Devillee">Peter Devillee</name><affiliation><nlm:aff id="A49">Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands</nlm:aff></affiliation><affiliation><nlm:aff id="A50">Department of Pathology, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Goldberg, Mark S" sort="Goldberg, Mark S" uniqKey="Goldberg M" first="Mark S" last="Goldberg">Mark S. Goldberg</name><affiliation><nlm:aff id="A51">Department of Medicine, McGill University, Montreal, Quebec, Canada</nlm:aff></affiliation><affiliation><nlm:aff id="A52">Division of Clinical Epidemiology, McGill University Health Centre, Royal Victoria Hospital, Montreal, Quebec, Canada</nlm:aff></affiliation></author><author><name sortKey="Lubinski, Jan" sort="Lubinski, Jan" uniqKey="Lubinski J" first="Jan" last="Lubinski">Jan Lubinski</name><affiliation><nlm:aff id="A53">Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland</nlm:aff></affiliation></author><author><name sortKey="Kristensen, Vessela" sort="Kristensen, Vessela" uniqKey="Kristensen V" first="Vessela" last="Kristensen">Vessela Kristensen</name><affiliation><nlm:aff id="A54">Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo, Norway</nlm:aff></affiliation><affiliation><nlm:aff id="A55">Faculty of Medicine (Faculty Division Ahus), Universitetet i Oslo, Oslo, Norway</nlm:aff></affiliation></author><author><name sortKey="Swerdlow, Anthony" sort="Swerdlow, Anthony" uniqKey="Swerdlow A" first="Anthony" last="Swerdlow">Anthony Swerdlow</name><affiliation><nlm:aff id="A1">Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, UK</nlm:aff></affiliation></author><author><name sortKey="Anton Culver, Hoda" sort="Anton Culver, Hoda" uniqKey="Anton Culver H" first="Hoda" last="Anton-Culver">Hoda Anton-Culver</name><affiliation><nlm:aff id="A56">Department of Epidemiology, University of California–Irvine, Irvine, California, USA</nlm:aff></affiliation></author><author><name sortKey="Dork, Thilo" sort="Dork, Thilo" uniqKey="Dork T" first="Thilo" last="Dörk">Thilo Dörk</name><affiliation><nlm:aff id="A57">Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany</nlm:aff></affiliation></author><author><name sortKey="Muir, Kenneth" sort="Muir, Kenneth" uniqKey="Muir K" first="Kenneth" last="Muir">Kenneth Muir</name><affiliation><nlm:aff id="A58">Warwick Medical School, Warwick University, Coventry, UK</nlm:aff></affiliation><affiliation><nlm:aff id="A59">Institute of Population Health, University of Manchester, Manchester, UK</nlm:aff></affiliation></author><author><name sortKey="Matsuo, Keitaro" sort="Matsuo, Keitaro" uniqKey="Matsuo K" first="Keitaro" last="Matsuo">Keitaro Matsuo</name><affiliation><nlm:aff id="A60">Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan</nlm:aff></affiliation></author><author><name sortKey="Wu, Anna H" sort="Wu, Anna H" uniqKey="Wu A" first="Anna H" last="Wu">Anna H. Wu</name><affiliation><nlm:aff id="A7">Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA</nlm:aff></affiliation></author><author><name sortKey="Radice, Paolo" sort="Radice, Paolo" uniqKey="Radice P" first="Paolo" last="Radice">Paolo Radice</name><affiliation><nlm:aff id="A61">Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy</nlm:aff></affiliation><affiliation><nlm:aff id="A62">IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy</nlm:aff></affiliation></author><author><name sortKey="Teo, Soo Hwang" sort="Teo, Soo Hwang" uniqKey="Teo S" first="Soo Hwang" last="Teo">Soo Hwang Teo</name><affiliation><nlm:aff id="A63">Cancer Research Initiatives Foundation, Sime Darby Medical Centre, Subang Jaya, University Malaya Cancer Research Institute, University Malaya, Kuala Lumpur, Malaysia</nlm:aff></affiliation><affiliation><nlm:aff id="A64">Breast Cancer Research Unit, University Malaya Cancer Research Institute, University Malaya, Kuala Lumpur, Malaysia</nlm:aff></affiliation></author><author><name sortKey="Shu, Xiao Ou" sort="Shu, Xiao Ou" uniqKey="Shu X" first="Xiao-Ou" last="Shu">Xiao-Ou Shu</name><affiliation><nlm:aff id="A48">Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA</nlm:aff></affiliation></author><author><name sortKey="Blot, William" sort="Blot, William" uniqKey="Blot W" first="William" last="Blot">William Blot</name><affiliation><nlm:aff id="A48">Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A65">International Epidemiology Institute, Rockville, Maryland, USA</nlm:aff></affiliation></author><author><name sortKey="Kang, Daehee" sort="Kang, Daehee" uniqKey="Kang D" first="Daehee" last="Kang">Daehee Kang</name><affiliation><nlm:aff id="A66">Seoul National University College of Medicine, Seoul, Korea</nlm:aff></affiliation></author><author><name sortKey="Hartman, Mikael" sort="Hartman, Mikael" uniqKey="Hartman M" first="Mikael" last="Hartman">Mikael Hartman</name><affiliation><nlm:aff id="A67">Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore</nlm:aff></affiliation><affiliation><nlm:aff id="A68">Saw Swee Hock School of Public Health, National University of Singapore, Singapore</nlm:aff></affiliation></author><author><name sortKey="Sangrajrang, Suleeporn" sort="Sangrajrang, Suleeporn" uniqKey="Sangrajrang S" first="Suleeporn" last="Sangrajrang">Suleeporn Sangrajrang</name><affiliation><nlm:aff id="A69">National Cancer Institute, Bangkok, Thailand</nlm:aff></affiliation></author><author><name sortKey="Shen, Chen Yang" sort="Shen, Chen Yang" uniqKey="Shen C" first="Chen-Yang" last="Shen">Chen-Yang Shen</name><affiliation><nlm:aff id="A70">Colleague of Public Health, China Medical University, Taichong, Taiwan</nlm:aff></affiliation><affiliation><nlm:aff id="A71">Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan</nlm:aff></affiliation></author><author><name sortKey="Southey, Melissa C" sort="Southey, Melissa C" uniqKey="Southey M" first="Melissa C" last="Southey">Melissa C. Southey</name><affiliation><nlm:aff id="A72">Department of Pathology, The University of Melbourne, Melbourne, Victoria, Australia</nlm:aff></affiliation></author><author><name sortKey="Park, Daniel J" sort="Park, Daniel J" uniqKey="Park D" first="Daniel J" last="Park">Daniel J. Park</name><affiliation><nlm:aff id="A72">Department of Pathology, The University of Melbourne, Melbourne, Victoria, Australia</nlm:aff></affiliation></author><author><name sortKey="Hammet, Fleur" sort="Hammet, Fleur" uniqKey="Hammet F" first="Fleur" last="Hammet">Fleur Hammet</name><affiliation><nlm:aff id="A72">Department of Pathology, The University of Melbourne, Melbourne, Victoria, Australia</nlm:aff></affiliation></author><author><name sortKey="Stone, Jennifer" sort="Stone, Jennifer" uniqKey="Stone J" first="Jennifer" last="Stone">Jennifer Stone</name><affiliation><nlm:aff id="A25">Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Victoria, Australia</nlm:aff></affiliation></author><author><name sortKey="Veer, Laura J Van" sort="Veer, Laura J Van" uniqKey="Veer L" first="Laura J Van" last="Veer">Laura J Van Veer</name><affiliation><nlm:aff id="A6">Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Rutgers, Emiel J" sort="Rutgers, Emiel J" uniqKey="Rutgers E" first="Emiel J" last="Rutgers">Emiel J. Rutgers</name><affiliation><nlm:aff id="A6">Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Lophatananon, Artitaya" sort="Lophatananon, Artitaya" uniqKey="Lophatananon A" first="Artitaya" last="Lophatananon">Artitaya Lophatananon</name><affiliation><nlm:aff id="A58">Warwick Medical School, Warwick University, Coventry, UK</nlm:aff></affiliation></author><author><name sortKey="Stewart Brown, Sarah" sort="Stewart Brown, Sarah" uniqKey="Stewart Brown S" first="Sarah" last="Stewart-Brown">Sarah Stewart-Brown</name><affiliation><nlm:aff id="A58">Warwick Medical School, Warwick University, Coventry, UK</nlm:aff></affiliation></author><author><name sortKey="Siriwanarangsan, Pornthep" sort="Siriwanarangsan, Pornthep" uniqKey="Siriwanarangsan P" first="Pornthep" last="Siriwanarangsan">Pornthep Siriwanarangsan</name><affiliation><nlm:aff id="A73">Ministry of Public Health, Bangkok, Thailand</nlm:aff></affiliation></author><author><name sortKey="Peto, Julian" sort="Peto, Julian" uniqKey="Peto J" first="Julian" last="Peto">Julian Peto</name><affiliation><nlm:aff id="A74">Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine, London, UK</nlm:aff></affiliation></author><author><name sortKey="Schrauder, Michael G" sort="Schrauder, Michael G" uniqKey="Schrauder M" first="Michael G" last="Schrauder">Michael G. Schrauder</name><affiliation><nlm:aff id="A14">Department of Gynecology and Obstetrics, University Breast Center Franconia, University Hospital Erlangen, Erlangen, Germany</nlm:aff></affiliation></author><author><name sortKey="Ekici, Arif B" sort="Ekici, Arif B" uniqKey="Ekici A" first="Arif B" last="Ekici">Arif B. Ekici</name><affiliation><nlm:aff id="A75">Institute of Human Genetics, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany</nlm:aff></affiliation></author><author><name sortKey="Beckmann, Matthias W" sort="Beckmann, Matthias W" uniqKey="Beckmann M" first="Matthias W" last="Beckmann">Matthias W. Beckmann</name><affiliation><nlm:aff id="A14">Department of Gynecology and Obstetrics, University Breast Center Franconia, University Hospital Erlangen, Erlangen, Germany</nlm:aff></affiliation></author><author><name sortKey="Silva, Isabel Dos Santos" sort="Silva, Isabel Dos Santos" uniqKey="Silva I" first="Isabel Dos Santos" last="Silva">Isabel Dos Santos Silva</name><affiliation><nlm:aff id="A74">Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine, London, UK</nlm:aff></affiliation></author><author><name sortKey="Johnson, Nichola" sort="Johnson, Nichola" uniqKey="Johnson N" first="Nichola" last="Johnson">Nichola Johnson</name><affiliation><nlm:aff id="A2">Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK</nlm:aff></affiliation></author><author><name sortKey="Warren, Helen" sort="Warren, Helen" uniqKey="Warren H" first="Helen" last="Warren">Helen Warren</name><affiliation><nlm:aff id="A74">Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine, London, UK</nlm:aff></affiliation></author><author><name sortKey="Tomlinson, Ian" sort="Tomlinson, Ian" uniqKey="Tomlinson I" first="Ian" last="Tomlinson">Ian Tomlinson</name><affiliation><nlm:aff id="A76">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff></affiliation><affiliation><nlm:aff id="A77">Oxford Biomedical Research Centre, University of Oxford, Oxford, UK</nlm:aff></affiliation></author><author><name sortKey="Kerin, Michael J" sort="Kerin, Michael J" uniqKey="Kerin M" first="Michael J" last="Kerin">Michael J. Kerin</name><affiliation><nlm:aff id="A78">Department of Surgery, Clinical Science Institute, University Hospital and National University of Ireland, Galway, Ireland</nlm:aff></affiliation></author><author><name sortKey="Miller, Nicola" sort="Miller, Nicola" uniqKey="Miller N" first="Nicola" last="Miller">Nicola Miller</name><affiliation><nlm:aff id="A78">Department of Surgery, Clinical Science Institute, University Hospital and National University of Ireland, Galway, Ireland</nlm:aff></affiliation></author><author><name sortKey="Marme, Federick" sort="Marme, Federick" uniqKey="Marme F" first="Federick" last="Marme">Federick Marme</name><affiliation><nlm:aff id="A35">Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A79">National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Schneeweiss, Andreas" sort="Schneeweiss, Andreas" uniqKey="Schneeweiss A" first="Andreas" last="Schneeweiss">Andreas Schneeweiss</name><affiliation><nlm:aff id="A35">Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A79">National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Sohn, Christof" sort="Sohn, Christof" uniqKey="Sohn C" first="Christof" last="Sohn">Christof Sohn</name><affiliation><nlm:aff id="A35">Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Truong, Therese" sort="Truong, Therese" uniqKey="Truong T" first="Therese" last="Truong">Therese Truong</name><affiliation><nlm:aff id="A33">University Paris–Sud, Unité Mixte de Recherche Scientifique (UMRS) 1018, Villejuif, France</nlm:aff></affiliation><affiliation><nlm:aff id="A34">INSERM (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), Environmental Epidemiology of Cancer, Villejuif, France</nlm:aff></affiliation></author><author><name sortKey="Laurent Puig, Pierre" sort="Laurent Puig, Pierre" uniqKey="Laurent Puig P" first="Pierre" last="Laurent-Puig">Pierre Laurent-Puig</name><affiliation><nlm:aff id="A80">INSERM, Université Paris Sorbonne Cité, UMRS 775, Paris, France</nlm:aff></affiliation></author><author><name sortKey="Kerbrat, Pierre" sort="Kerbrat, Pierre" uniqKey="Kerbrat P" first="Pierre" last="Kerbrat">Pierre Kerbrat</name><affiliation><nlm:aff id="A81">Centre Eugène Marquis, Department of Medical Oncology, Rennes, France</nlm:aff></affiliation></author><author><name sortKey="Nordestgaard, B Rge G" sort="Nordestgaard, B Rge G" uniqKey="Nordestgaard B" first="B Rge G" last="Nordestgaard">B Rge G. Nordestgaard</name><affiliation><nlm:aff id="A28">Copenhagen General Population Study, Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark</nlm:aff></affiliation></author><author><name sortKey="Nielsen, Sune F" sort="Nielsen, Sune F" uniqKey="Nielsen S" first="Sune F" last="Nielsen">Sune F. Nielsen</name><affiliation><nlm:aff id="A28">Copenhagen General Population Study, Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark</nlm:aff></affiliation></author><author><name sortKey="Flyger, Henrik" sort="Flyger, Henrik" uniqKey="Flyger H" first="Henrik" last="Flyger">Henrik Flyger</name><affiliation><nlm:aff id="A82">Department of Breast Surgery, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Denmark</nlm:aff></affiliation></author><author><name sortKey="Milne, Roger L" sort="Milne, Roger L" uniqKey="Milne R" first="Roger L" last="Milne">Roger L. Milne</name><affiliation><nlm:aff id="A83">Genetic & Molecular Epidemiology Group, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), Madrid, Spain</nlm:aff></affiliation></author><author><name sortKey="Perez, Jose Ignacio Arias" sort="Perez, Jose Ignacio Arias" uniqKey="Perez J" first="Jose Ignacio Arias" last="Perez">Jose Ignacio Arias Perez</name><affiliation><nlm:aff id="A84">Servicio de Cirugía General y Especialidades, Hospital Monte Naranco, Oviedo, Spain</nlm:aff></affiliation></author><author><name sortKey="Menendez, Primitiva" sort="Menendez, Primitiva" uniqKey="Menendez P" first="Primitiva" last="Menéndez">Primitiva Menéndez</name><affiliation><nlm:aff id="A85">Servicio de Anatomía Patológica, Hospital Monte Naranco, Oviedo, Spain</nlm:aff></affiliation></author><author><name sortKey="Muller, Heiko" sort="Muller, Heiko" uniqKey="Muller H" first="Heiko" last="Müller">Heiko Müller</name><affiliation><nlm:aff id="A40">Division of Clinical Epidemiology and Aging Research, DKFZ, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Arndt, Volker" sort="Arndt, Volker" uniqKey="Arndt V" first="Volker" last="Arndt">Volker Arndt</name><affiliation><nlm:aff id="A40">Division of Clinical Epidemiology and Aging Research, DKFZ, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Stegmaier, Christa" sort="Stegmaier, Christa" uniqKey="Stegmaier C" first="Christa" last="Stegmaier">Christa Stegmaier</name><affiliation><nlm:aff id="A86">Saarland Cancer Registry, Saarbrücken, Germany</nlm:aff></affiliation></author><author><name sortKey="Lichtner, Peter" sort="Lichtner, Peter" uniqKey="Lichtner P" first="Peter" last="Lichtner">Peter Lichtner</name><affiliation><nlm:aff id="A87">Institute of Human Genetics, Technische Universität München, Munich, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A88">Institute of Human Genetics, Helmholtz Zentrum München–German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Lochmann, Magdalena" sort="Lochmann, Magdalena" uniqKey="Lochmann M" first="Magdalena" last="Lochmann">Magdalena Lochmann</name><affiliation><nlm:aff id="A46">Division of Gynaecology and Obstetrics, Technische Universität München, Munich, Germany</nlm:aff></affiliation></author><author><name sortKey="Justenhoven, Christina" sort="Justenhoven, Christina" uniqKey="Justenhoven C" first="Christina" last="Justenhoven">Christina Justenhoven</name><affiliation><nlm:aff id="A16">Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A17">University of Tübingen, Tübingen, Germany</nlm:aff></affiliation></author><author><name sortKey="Ko, Yon Dschun" sort="Ko, Yon Dschun" uniqKey="Ko Y" first="Yon-Dschun" last="Ko">Yon-Dschun Ko</name><affiliation><nlm:aff id="A89">Department of Internal Medicine, Evangelische Kliniken Bonn, Johanniter Krankenhaus, Bonn, Germany</nlm:aff></affiliation></author><author><name sortKey="Muranen, Taru A" sort="Muranen, Taru A" uniqKey="Muranen T" first="Taru A" last="Muranen">Taru A. Muranen</name><affiliation><nlm:aff id="A21">Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Aittom Ki, Kristiina" sort="Aittom Ki, Kristiina" uniqKey="Aittom Ki K" first="Kristiina" last="Aittom Ki">Kristiina Aittom Ki</name><affiliation><nlm:aff id="A91">Department of Clinical Genetics, Helsinki University Central Hospital, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Blomqvist, Carl" sort="Blomqvist, Carl" uniqKey="Blomqvist C" first="Carl" last="Blomqvist">Carl Blomqvist</name><affiliation><nlm:aff id="A92">Department of Oncology, Helsinki University Central Hospital, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Greco, Dario" sort="Greco, Dario" uniqKey="Greco D" first="Dario" last="Greco">Dario Greco</name><affiliation><nlm:aff id="A21">Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Heikkinen, Tuomas" sort="Heikkinen, Tuomas" uniqKey="Heikkinen T" first="Tuomas" last="Heikkinen">Tuomas Heikkinen</name><affiliation><nlm:aff id="A21">Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Ito, Hidemi" sort="Ito, Hidemi" uniqKey="Ito H" first="Hidemi" last="Ito">Hidemi Ito</name><affiliation><nlm:aff id="A60">Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan</nlm:aff></affiliation></author><author><name sortKey="Iwata, Hiroji" sort="Iwata, Hiroji" uniqKey="Iwata H" first="Hiroji" last="Iwata">Hiroji Iwata</name><affiliation><nlm:aff id="A93">Department of Breast Oncology, Aichi Cancer Center Hospital, Nagoya, Japan</nlm:aff></affiliation></author><author><name sortKey="Yatabe, Yasushi" sort="Yatabe, Yasushi" uniqKey="Yatabe Y" first="Yasushi" last="Yatabe">Yasushi Yatabe</name><affiliation><nlm:aff id="A94">Department of Pathology and Molecular Diagnostics, Aichi Cancer Center Hospital, Nagoya, Japan</nlm:aff></affiliation></author><author><name sortKey="Antonenkova, Natalia N" sort="Antonenkova, Natalia N" uniqKey="Antonenkova N" first="Natalia N" last="Antonenkova">Natalia N. Antonenkova</name><affiliation><nlm:aff id="A95">N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus</nlm:aff></affiliation></author><author><name sortKey="Margolin, Sara" sort="Margolin, Sara" uniqKey="Margolin S" first="Sara" last="Margolin">Sara Margolin</name><affiliation><nlm:aff id="A96">Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden</nlm:aff></affiliation></author><author><name sortKey="Kataja, Vesa" sort="Kataja, Vesa" uniqKey="Kataja V" first="Vesa" last="Kataja">Vesa Kataja</name><affiliation><nlm:aff id="A42">School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, Kuopio, Finland</nlm:aff></affiliation><affiliation><nlm:aff id="A43">Biocenter Kuopio, Cancer Center of Eastern Finland, University of Eastern Finland, Kuopio, Finland</nlm:aff></affiliation><affiliation><nlm:aff id="A97">Cancer Center, Kuopio University Hospital, Kuopio, Finland</nlm:aff></affiliation></author><author><name sortKey="Kosma, Veli Matti" sort="Kosma, Veli Matti" uniqKey="Kosma V" first="Veli-Matti" last="Kosma">Veli-Matti Kosma</name><affiliation><nlm:aff id="A41">Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland</nlm:aff></affiliation><affiliation><nlm:aff id="A43">Biocenter Kuopio, Cancer Center of Eastern Finland, University of Eastern Finland, Kuopio, Finland</nlm:aff></affiliation></author><author><name sortKey="Hartikainen, Jaana M" sort="Hartikainen, Jaana M" uniqKey="Hartikainen J" first="Jaana M" last="Hartikainen">Jaana M. Hartikainen</name><affiliation><nlm:aff id="A41">Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland</nlm:aff></affiliation><affiliation><nlm:aff id="A43">Biocenter Kuopio, Cancer Center of Eastern Finland, University of Eastern Finland, Kuopio, Finland</nlm:aff></affiliation></author><author><name sortKey="Balleine, Rosemary" sort="Balleine, Rosemary" uniqKey="Balleine R" first="Rosemary" last="Balleine">Rosemary Balleine</name><affiliation><nlm:aff id="A98">Western Sydney Local Health District, Westmead Millennium Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia</nlm:aff></affiliation><affiliation><nlm:aff id="A99">Nepean Blue Mountains Local Health District, Westmead Millennium Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia</nlm:aff></affiliation></author><author><name sortKey="Tseng, Chiu Chen" sort="Tseng, Chiu Chen" uniqKey="Tseng C" first="Chiu-Chen" last="Tseng">Chiu-Chen Tseng</name><affiliation><nlm:aff id="A7">Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA</nlm:aff></affiliation></author><author><name sortKey="Van Den Berg, David" sort="Van Den Berg, David" uniqKey="Van Den Berg D" first="David" last="Van Den Berg">David Van Den Berg</name><affiliation><nlm:aff id="A7">Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA</nlm:aff></affiliation></author><author><name sortKey="Stram, Daniel O" sort="Stram, Daniel O" uniqKey="Stram D" first="Daniel O" last="Stram">Daniel O. Stram</name><affiliation><nlm:aff id="A7">Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA</nlm:aff></affiliation></author><author><name sortKey="Neven, Patrick" sort="Neven, Patrick" uniqKey="Neven P" first="Patrick" last="Neven">Patrick Neven</name><affiliation><nlm:aff id="A100">Multidisciplinary Breast Center, University Hospital Gasthuisberg, Department of Oncology, University of Leuven, Leuven, Belgium</nlm:aff></affiliation></author><author><name sortKey="Dieudonne, Anne Sophie" sort="Dieudonne, Anne Sophie" uniqKey="Dieudonne A" first="Anne-Sophie" last="Dieudonné">Anne-Sophie Dieudonné</name><affiliation><nlm:aff id="A100">Multidisciplinary Breast Center, University Hospital Gasthuisberg, Department of Oncology, University of Leuven, Leuven, Belgium</nlm:aff></affiliation></author><author><name sortKey="Leunen, Karin" sort="Leunen, Karin" uniqKey="Leunen K" first="Karin" last="Leunen">Karin Leunen</name><affiliation><nlm:aff id="A100">Multidisciplinary Breast Center, University Hospital Gasthuisberg, Department of Oncology, University of Leuven, Leuven, Belgium</nlm:aff></affiliation></author><author><name sortKey="Rudolph, Anja" sort="Rudolph, Anja" uniqKey="Rudolph A" first="Anja" last="Rudolph">Anja Rudolph</name><affiliation><nlm:aff id="A18">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Nickels, Stefan" sort="Nickels, Stefan" uniqKey="Nickels S" first="Stefan" last="Nickels">Stefan Nickels</name><affiliation><nlm:aff id="A18">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Flesch Janys, Dieter" sort="Flesch Janys, Dieter" uniqKey="Flesch Janys D" first="Dieter" last="Flesch-Janys">Dieter Flesch-Janys</name><affiliation><nlm:aff id="A101">Department of Cancer Epidemiology/Clinical Cancer Registry, University Clinic Hamburg-Eppendorf, Hamburg, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A102">Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg, Germany</nlm:aff></affiliation></author><author><name sortKey="Peterlongo, Paolo" sort="Peterlongo, Paolo" uniqKey="Peterlongo P" first="Paolo" last="Peterlongo">Paolo Peterlongo</name><affiliation><nlm:aff id="A61">Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy</nlm:aff></affiliation><affiliation><nlm:aff id="A62">IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy</nlm:aff></affiliation></author><author><name sortKey="Peissel, Bernard" sort="Peissel, Bernard" uniqKey="Peissel B" first="Bernard" last="Peissel">Bernard Peissel</name><affiliation><nlm:aff id="A103">Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS INT, Milan, Italy</nlm:aff></affiliation></author><author><name sortKey="Bernard, Loris" sort="Bernard, Loris" uniqKey="Bernard L" first="Loris" last="Bernard">Loris Bernard</name><affiliation><nlm:aff id="A104">Department of Experimental Oncology, Istituto Europeo di Oncologia, Milan, Italy</nlm:aff></affiliation><affiliation><nlm:aff id="A105">Cogentech Cancer Genetic Test Laboratory, Milan, Italy</nlm:aff></affiliation></author><author><name sortKey="Olson, Janet E" sort="Olson, Janet E" uniqKey="Olson J" first="Janet E" last="Olson">Janet E. Olson</name><affiliation><nlm:aff id="A3">Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota, USA</nlm:aff></affiliation></author><author><name sortKey="Wang, Xianshu" sort="Wang, Xianshu" uniqKey="Wang X" first="Xianshu" last="Wang">Xianshu Wang</name><affiliation><nlm:aff id="A3">Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A106">Department of Laboratory Medicine and Pathology, Division of Experimental Pathology, Mayo Clinic, Rochester, Minnesota, USA</nlm:aff></affiliation></author><author><name sortKey="Stevens, Kristen" sort="Stevens, Kristen" uniqKey="Stevens K" first="Kristen" last="Stevens">Kristen Stevens</name><affiliation><nlm:aff id="A3">Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota, USA</nlm:aff></affiliation></author><author><name sortKey="Severi, Gianluca" sort="Severi, Gianluca" uniqKey="Severi G" first="Gianluca" last="Severi">Gianluca Severi</name><affiliation><nlm:aff id="A22">Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia</nlm:aff></affiliation><affiliation><nlm:aff id="A25">Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Victoria, Australia</nlm:aff></affiliation></author><author><name sortKey="Baglietto, Laura" sort="Baglietto, Laura" uniqKey="Baglietto L" first="Laura" last="Baglietto">Laura Baglietto</name><affiliation><nlm:aff id="A22">Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia</nlm:aff></affiliation><affiliation><nlm:aff id="A25">Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Victoria, Australia</nlm:aff></affiliation></author><author><name sortKey="Mclean, Catriona" sort="Mclean, Catriona" uniqKey="Mclean C" first="Catriona" last="Mclean">Catriona Mclean</name><affiliation><nlm:aff id="A107">Department of Anatomical Pathology, The Alfred Hospital, Melbourne, Victoria, Australia</nlm:aff></affiliation></author><author><name sortKey="Coetzee, Gerhard A" sort="Coetzee, Gerhard A" uniqKey="Coetzee G" first="Gerhard A" last="Coetzee">Gerhard A. Coetzee</name><affiliation><nlm:aff id="A7">Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A108">Department of Urology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA</nlm:aff></affiliation></author><author><name sortKey="Feng, Ye" sort="Feng, Ye" uniqKey="Feng Y" first="Ye" last="Feng">Ye Feng</name><affiliation><nlm:aff id="A7">Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA</nlm:aff></affiliation></author><author><name sortKey="Henderson, Brian E" sort="Henderson, Brian E" uniqKey="Henderson B" first="Brian E" last="Henderson">Brian E. Henderson</name><affiliation><nlm:aff id="A7">Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA</nlm:aff></affiliation></author><author><name sortKey="Schumacher, Fredrick" sort="Schumacher, Fredrick" uniqKey="Schumacher F" first="Fredrick" last="Schumacher">Fredrick Schumacher</name><affiliation><nlm:aff id="A7">Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA</nlm:aff></affiliation></author><author><name sortKey="Bogdanova, Natalia V" sort="Bogdanova, Natalia V" uniqKey="Bogdanova N" first="Natalia V" last="Bogdanova">Natalia V. Bogdanova</name><affiliation><nlm:aff id="A57">Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A109">Department of Radiation Oncology, Hannover Medical School, Hannover, Germany</nlm:aff></affiliation></author><author><name sortKey="Labreche, France" sort="Labreche, France" uniqKey="Labreche F" first="France" last="Labrèche">France Labrèche</name><affiliation><nlm:aff id="A110">Département de Médecine Sociale et Préventive, Département de Santé Environnementale et Santé au Travail, Université de Montréal, Montreal, Quebec, Canada</nlm:aff></affiliation></author><author><name sortKey="Dumont, Martine" sort="Dumont, Martine" uniqKey="Dumont M" first="Martine" last="Dumont">Martine Dumont</name><affiliation><nlm:aff id="A111">Cancer Genomics Laboratory, Centre Hospitalier Universitaire de Québec and Laval University, Quebec City, Quebec, Canada</nlm:aff></affiliation></author><author><name sortKey="Yip, Cheng Har" sort="Yip, Cheng Har" uniqKey="Yip C" first="Cheng Har" last="Yip">Cheng Har Yip</name><affiliation><nlm:aff id="A64">Breast Cancer Research Unit, University Malaya Cancer Research Institute, University Malaya, Kuala Lumpur, Malaysia</nlm:aff></affiliation></author><author><name sortKey="Taib, Nur Aishah Mohd" sort="Taib, Nur Aishah Mohd" uniqKey="Taib N" first="Nur Aishah Mohd" last="Taib">Nur Aishah Mohd Taib</name><affiliation><nlm:aff id="A64">Breast Cancer Research Unit, University Malaya Cancer Research Institute, University Malaya, Kuala Lumpur, Malaysia</nlm:aff></affiliation></author><author><name sortKey="Cheng, Ching Yu" sort="Cheng, Ching Yu" uniqKey="Cheng C" first="Ching-Yu" last="Cheng">Ching-Yu Cheng</name><affiliation><nlm:aff id="A67">Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore</nlm:aff></affiliation><affiliation><nlm:aff id="A68">Saw Swee Hock School of Public Health, National University of Singapore, Singapore</nlm:aff></affiliation><affiliation><nlm:aff id="A112">Singapore Eye Research Institute, National University of Singapore, Singapore</nlm:aff></affiliation></author><author><name sortKey="Shrubsole, Martha" sort="Shrubsole, Martha" uniqKey="Shrubsole M" first="Martha" last="Shrubsole">Martha Shrubsole</name><affiliation><nlm:aff id="A48">Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA</nlm:aff></affiliation></author><author><name sortKey="Long, Jirong" sort="Long, Jirong" uniqKey="Long J" first="Jirong" last="Long">Jirong Long</name><affiliation><nlm:aff id="A48">Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA</nlm:aff></affiliation></author><author><name sortKey="Pylk S, Katri" sort="Pylk S, Katri" uniqKey="Pylk S K" first="Katri" last="Pylk S">Katri Pylk S</name><affiliation><nlm:aff id="A39">Laboratory of Cancer Genetics and Tumor Biology, Department of Clinical Genetics, Biocenter Oulu, University of Oulu, Oulu University Hospital, Oulu, Finland</nlm:aff></affiliation></author><author><name sortKey="Jukkola Vuorinen, Arja" sort="Jukkola Vuorinen, Arja" uniqKey="Jukkola Vuorinen A" first="Arja" last="Jukkola-Vuorinen">Arja Jukkola-Vuorinen</name><affiliation><nlm:aff id="A113">Department of Oncology, Oulu University Hospital, University of Oulu, Oulu, Finland</nlm:aff></affiliation></author><author><name sortKey="Kauppila, Saila" sort="Kauppila, Saila" uniqKey="Kauppila S" first="Saila" last="Kauppila">Saila Kauppila</name><affiliation><nlm:aff id="A114">Department of Pathology, Oulu University Hospital, University of Oulu, Oulu, Finland</nlm:aff></affiliation></author><author><name sortKey="Knight, Julia A" sort="Knight, Julia A" uniqKey="Knight J" first="Julia A" last="Knight">Julia A. Knight</name><affiliation><nlm:aff id="A32">Ontario Cancer Genetics Network, Fred A. Litwin Center for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada</nlm:aff></affiliation><affiliation><nlm:aff id="A115">Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada</nlm:aff></affiliation><affiliation><nlm:aff id="A116">Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada</nlm:aff></affiliation></author><author><name sortKey="Glendon, Gord" sort="Glendon, Gord" uniqKey="Glendon G" first="Gord" last="Glendon">Gord Glendon</name><affiliation><nlm:aff id="A32">Ontario Cancer Genetics Network, Fred A. Litwin Center for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada</nlm:aff></affiliation></author><author><name sortKey="Mulligan, Anna Marie" sort="Mulligan, Anna Marie" uniqKey="Mulligan A" first="Anna Marie" last="Mulligan">Anna Marie Mulligan</name><affiliation><nlm:aff id="A117">Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada</nlm:aff></affiliation><affiliation><nlm:aff id="A118">Department of Laboratory Medicine, Keenan Research Centre of the Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, Ontario, Canada</nlm:aff></affiliation></author><author><name sortKey="Tollenaar, Robertus A E M" sort="Tollenaar, Robertus A E M" uniqKey="Tollenaar R" first="Robertus A E M" last="Tollenaar">Robertus A E M. Tollenaar</name><affiliation><nlm:aff id="A119">Department of Surgical Oncology, Leiden University Medical Center, Leiden, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Seynaeve, Caroline M" sort="Seynaeve, Caroline M" uniqKey="Seynaeve C" first="Caroline M" last="Seynaeve">Caroline M. Seynaeve</name><affiliation><nlm:aff id="A38">Department of Medical Oncology, Erasmus University Medical Center–Daniel Den Hoed Cancer Center, Rotterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Kriege, Mieke" sort="Kriege, Mieke" uniqKey="Kriege M" first="Mieke" last="Kriege">Mieke Kriege</name><affiliation><nlm:aff id="A38">Department of Medical Oncology, Erasmus University Medical Center–Daniel Den Hoed Cancer Center, Rotterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Hooning, Maartje J" sort="Hooning, Maartje J" uniqKey="Hooning M" first="Maartje J" last="Hooning">Maartje J. Hooning</name><affiliation><nlm:aff id="A38">Department of Medical Oncology, Erasmus University Medical Center–Daniel Den Hoed Cancer Center, Rotterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Van Den Ouweland, Ans M W" sort="Van Den Ouweland, Ans M W" uniqKey="Van Den Ouweland A" first="Ans M W" last="Van Den Ouweland">Ans M W. Van Den Ouweland</name><affiliation><nlm:aff id="A120">Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Van Deurzen, Carolien H M" sort="Van Deurzen, Carolien H M" uniqKey="Van Deurzen C" first="Carolien H M" last="Van Deurzen">Carolien H M. Van Deurzen</name><affiliation><nlm:aff id="A50">Department of Pathology, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Lu, Wei" sort="Lu, Wei" uniqKey="Lu W" first="Wei" last="Lu">Wei Lu</name><affiliation><nlm:aff id="A121">Shanghai Center for Disease Control and Prevention, Shanghai, China</nlm:aff></affiliation></author><author><name sortKey="Gao, Yu Tang" sort="Gao, Yu Tang" uniqKey="Gao Y" first="Yu-Tang" last="Gao">Yu-Tang Gao</name><affiliation><nlm:aff id="A122">Department of Epidemiology, Shanghai Cancer Institute, Shanghai, China</nlm:aff></affiliation></author><author><name sortKey="Cai, Hui" sort="Cai, Hui" uniqKey="Cai H" first="Hui" last="Cai">Hui Cai</name><affiliation><nlm:aff id="A48">Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA</nlm:aff></affiliation></author><author><name sortKey="Balasubramanian, Sabapathy P" sort="Balasubramanian, Sabapathy P" uniqKey="Balasubramanian S" first="Sabapathy P" last="Balasubramanian">Sabapathy P. Balasubramanian</name><affiliation><nlm:aff id="A24">Cancer Research UK/Yorkshire Cancer Research Sheffield Cancer Research Centre, Department of Oncology, University of Sheffield, Sheffield, UK</nlm:aff></affiliation></author><author><name sortKey="Cross, Simon S" sort="Cross, Simon S" uniqKey="Cross S" first="Simon S" last="Cross">Simon S. Cross</name><affiliation><nlm:aff id="A123">Academic Unit of Pathology, Department of Neuroscience, University of Sheffield, Sheffield, UK</nlm:aff></affiliation></author><author><name sortKey="Reed, Malcolm W R" sort="Reed, Malcolm W R" uniqKey="Reed M" first="Malcolm W R" last="Reed">Malcolm W R. Reed</name><affiliation><nlm:aff id="A24">Cancer Research UK/Yorkshire Cancer Research Sheffield Cancer Research Centre, Department of Oncology, University of Sheffield, Sheffield, UK</nlm:aff></affiliation></author><author><name sortKey="Signorello, Lisa" sort="Signorello, Lisa" uniqKey="Signorello L" first="Lisa" last="Signorello">Lisa Signorello</name><affiliation><nlm:aff id="A48">Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA</nlm:aff></affiliation></author><author><name sortKey="Cai, Qiuyin" sort="Cai, Qiuyin" uniqKey="Cai Q" first="Qiuyin" last="Cai">Qiuyin Cai</name><affiliation><nlm:aff id="A52">Division of Clinical Epidemiology, McGill University Health Centre, Royal Victoria Hospital, Montreal, Quebec, Canada</nlm:aff></affiliation></author><author><name sortKey="Shah, Mitul" sort="Shah, Mitul" uniqKey="Shah M" first="Mitul" last="Shah">Mitul Shah</name><affiliation><nlm:aff id="A124">Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Miao, Hui" sort="Miao, Hui" uniqKey="Miao H" first="Hui" last="Miao">Hui Miao</name><affiliation><nlm:aff id="A68">Saw Swee Hock School of Public Health, National University of Singapore, Singapore</nlm:aff></affiliation></author><author><name sortKey="Chan, Ching Wan" sort="Chan, Ching Wan" uniqKey="Chan C" first="Ching Wan" last="Chan">Ching Wan Chan</name><affiliation><nlm:aff id="A125">Department of Surgery, National University Health System, Singapore</nlm:aff></affiliation></author><author><name sortKey="Chia, Kee Seng" sort="Chia, Kee Seng" uniqKey="Chia K" first="Kee Seng" last="Chia">Kee Seng Chia</name><affiliation><nlm:aff id="A68">Saw Swee Hock School of Public Health, National University of Singapore, Singapore</nlm:aff></affiliation></author><author><name sortKey="Jakubowska, Anna" sort="Jakubowska, Anna" uniqKey="Jakubowska A" first="Anna" last="Jakubowska">Anna Jakubowska</name><affiliation><nlm:aff id="A53">Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland</nlm:aff></affiliation></author><author><name sortKey="Jaworska, Katarzyna" sort="Jaworska, Katarzyna" uniqKey="Jaworska K" first="Katarzyna" last="Jaworska">Katarzyna Jaworska</name><affiliation><nlm:aff id="A53">Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland</nlm:aff></affiliation></author><author><name sortKey="Durda, Katarzyna" sort="Durda, Katarzyna" uniqKey="Durda K" first="Katarzyna" last="Durda">Katarzyna Durda</name><affiliation><nlm:aff id="A53">Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland</nlm:aff></affiliation></author><author><name sortKey="Hsiung, Chia Ni" sort="Hsiung, Chia Ni" uniqKey="Hsiung C" first="Chia-Ni" last="Hsiung">Chia-Ni Hsiung</name><affiliation><nlm:aff id="A71">Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan</nlm:aff></affiliation></author><author><name sortKey="Wu, Pei Ei" sort="Wu, Pei Ei" uniqKey="Wu P" first="Pei-Ei" last="Wu">Pei-Ei Wu</name><affiliation><nlm:aff id="A126">Taiwan Biobank, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan</nlm:aff></affiliation></author><author><name sortKey="Yu, Jyh Cherng" sort="Yu, Jyh Cherng" uniqKey="Yu J" first="Jyh-Cherng" last="Yu">Jyh-Cherng Yu</name><affiliation><nlm:aff id="A127">Department of Surgery, Tri-Service General Hospital, Taipei, Taiwan</nlm:aff></affiliation></author><author><name sortKey="Ashworth, Alan" sort="Ashworth, Alan" uniqKey="Ashworth A" first="Alan" last="Ashworth">Alan Ashworth</name><affiliation><nlm:aff id="A2">Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK</nlm:aff></affiliation></author><author><name sortKey="Jones, Michael" sort="Jones, Michael" uniqKey="Jones M" first="Michael" last="Jones">Michael Jones</name><affiliation><nlm:aff id="A1">Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, UK</nlm:aff></affiliation></author><author><name sortKey="Tessier, Daniel C" sort="Tessier, Daniel C" uniqKey="Tessier D" first="Daniel C" last="Tessier">Daniel C. Tessier</name><affiliation><nlm:aff id="A128">McGill University and Génome Québec Innovation Centre, Montreal, Québec, Canada</nlm:aff></affiliation></author><author><name sortKey="Gonzalez Neira, Anna" sort="Gonzalez Neira, Anna" uniqKey="Gonzalez Neira A" first="Anna" last="González-Neira">Anna González-Neira</name><affiliation><nlm:aff id="A129">Human Genotyping Unit–CEGEN, Human Cancer Genetics Programme, CNIO, Madrid, Spain</nlm:aff></affiliation></author><author><name sortKey="Pita, Guillermo" sort="Pita, Guillermo" uniqKey="Pita G" first="Guillermo" last="Pita">Guillermo Pita</name><affiliation><nlm:aff id="A129">Human Genotyping Unit–CEGEN, Human Cancer Genetics Programme, CNIO, Madrid, Spain</nlm:aff></affiliation></author><author><name sortKey="Alonso, M Rosario" sort="Alonso, M Rosario" uniqKey="Alonso M" first="M Rosario" last="Alonso">M Rosario Alonso</name><affiliation><nlm:aff id="A129">Human Genotyping Unit–CEGEN, Human Cancer Genetics Programme, CNIO, Madrid, Spain</nlm:aff></affiliation></author><author><name sortKey="Vincent, Daniel" sort="Vincent, Daniel" uniqKey="Vincent D" first="Daniel" last="Vincent">Daniel Vincent</name><affiliation><nlm:aff id="A128">McGill University and Génome Québec Innovation Centre, Montreal, Québec, Canada</nlm:aff></affiliation></author><author><name sortKey="Bacot, Francois" sort="Bacot, Francois" uniqKey="Bacot F" first="Francois" last="Bacot">Francois Bacot</name><affiliation><nlm:aff id="A128">McGill University and Génome Québec Innovation Centre, Montreal, Québec, Canada</nlm:aff></affiliation></author><author><name sortKey="Ambrosone, Christine B" sort="Ambrosone, Christine B" uniqKey="Ambrosone C" first="Christine B" last="Ambrosone">Christine B. Ambrosone</name><affiliation><nlm:aff id="A130">Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, New York, USA</nlm:aff></affiliation></author><author><name sortKey="Bandera, Elisa V" sort="Bandera, Elisa V" uniqKey="Bandera E" first="Elisa V" last="Bandera">Elisa V. Bandera</name><affiliation><nlm:aff id="A131">The Cancer Institute of New Jersey, New Brunswick, New Jersey, USA</nlm:aff></affiliation></author><author><name sortKey="John, Esther M" sort="John, Esther M" uniqKey="John E" first="Esther M" last="John">Esther M. John</name><affiliation><nlm:aff id="A132">Cancer Prevention Institute of California, Fremont, California, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A133">Department of Health Research and Policy, Division of Epidemiology, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California, USA</nlm:aff></affiliation></author><author><name sortKey="Chen, Gary K" sort="Chen, Gary K" uniqKey="Chen G" first="Gary K" last="Chen">Gary K. Chen</name><affiliation><nlm:aff id="A7">Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA</nlm:aff></affiliation></author><author><name sortKey="Hu, Jennifer J" sort="Hu, Jennifer J" uniqKey="Hu J" first="Jennifer J" last="Hu">Jennifer J. Hu</name><affiliation><nlm:aff id="A134">Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A135">Department of Epidemiology and Public Health, University of Miami Miller School of Medicine, Miami, Florida, USA</nlm:aff></affiliation></author><author><name sortKey="Rodriguez Gil, Jorge L" sort="Rodriguez Gil, Jorge L" uniqKey="Rodriguez Gil J" first="Jorge L" last="Rodriguez-Gil">Jorge L. Rodriguez-Gil</name><affiliation><nlm:aff id="A134">Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A135">Department of Epidemiology and Public Health, University of Miami Miller School of Medicine, Miami, Florida, USA</nlm:aff></affiliation></author><author><name sortKey="Bernstein, Leslie" sort="Bernstein, Leslie" uniqKey="Bernstein L" first="Leslie" last="Bernstein">Leslie Bernstein</name><affiliation><nlm:aff id="A136">Division of Cancer Etiology, Department of Population Science, Beckman Research Institute, City of Hope, Duarte, California, USA</nlm:aff></affiliation></author><author><name sortKey="Press, Michael F" sort="Press, Michael F" uniqKey="Press M" first="Michael F" last="Press">Michael F. Press</name><affiliation><nlm:aff id="A137">Department of Pathology, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA</nlm:aff></affiliation></author><author><name sortKey="Ziegler, Regina G" sort="Ziegler, Regina G" uniqKey="Ziegler R" first="Regina G" last="Ziegler">Regina G. Ziegler</name><affiliation><nlm:aff id="A138">Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA</nlm:aff></affiliation></author><author><name sortKey="Millikan, Robert M" sort="Millikan, Robert M" uniqKey="Millikan R" first="Robert M" last="Millikan">Robert M. Millikan</name><affiliation><nlm:aff id="A139">Department of Epidemiology, Gillings School of Global Public Health, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, Chapel Hill, North Carolina, USA</nlm:aff></affiliation></author><author><name sortKey="Deming Halverson, Sandra L" sort="Deming Halverson, Sandra L" uniqKey="Deming Halverson S" first="Sandra L" last="Deming-Halverson">Sandra L. Deming-Halverson</name><affiliation><nlm:aff id="A48">Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA</nlm:aff></affiliation></author><author><name sortKey="Nyante, Sarah" sort="Nyante, Sarah" uniqKey="Nyante S" first="Sarah" last="Nyante">Sarah Nyante</name><affiliation><nlm:aff id="A139">Department of Epidemiology, Gillings School of Global Public Health, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, Chapel Hill, North Carolina, USA</nlm:aff></affiliation></author><author><name sortKey="Ingles, Sue A" sort="Ingles, Sue A" uniqKey="Ingles S" first="Sue A" last="Ingles">Sue A. Ingles</name><affiliation><nlm:aff id="A7">Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA</nlm:aff></affiliation></author><author><name sortKey="Waisfisz, Quinten" sort="Waisfisz, Quinten" uniqKey="Waisfisz Q" first="Quinten" last="Waisfisz">Quinten Waisfisz</name><affiliation><nlm:aff id="A140">Section of Oncogenetics, Department of Clinical Genetics, VU University Medical Center, Amsterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Tsimiklis, Helen" sort="Tsimiklis, Helen" uniqKey="Tsimiklis H" first="Helen" last="Tsimiklis">Helen Tsimiklis</name><affiliation><nlm:aff id="A141">Genetic Epidemiology Laboratory, Department of Pathology, The University of Melbourne, Melbourne, Victoria, Australia</nlm:aff></affiliation></author><author><name sortKey="Makalic, Enes" sort="Makalic, Enes" uniqKey="Makalic E" first="Enes" last="Makalic">Enes Makalic</name><affiliation><nlm:aff id="A23">School of Population Health, The University of Melbourne, Melbourne, Victoria, Australia</nlm:aff></affiliation><affiliation><nlm:aff id="A25">Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Victoria, Australia</nlm:aff></affiliation></author><author><name sortKey="Schmidt, Daniel" sort="Schmidt, Daniel" uniqKey="Schmidt D" first="Daniel" last="Schmidt">Daniel Schmidt</name><affiliation><nlm:aff id="A23">School of Population Health, The University of Melbourne, Melbourne, Victoria, Australia</nlm:aff></affiliation><affiliation><nlm:aff id="A25">Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Victoria, Australia</nlm:aff></affiliation></author><author><name sortKey="Bui, Minh" sort="Bui, Minh" uniqKey="Bui M" first="Minh" last="Bui">Minh Bui</name><affiliation><nlm:aff id="A23">School of Population Health, The University of Melbourne, Melbourne, Victoria, Australia</nlm:aff></affiliation><affiliation><nlm:aff id="A25">Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Victoria, Australia</nlm:aff></affiliation></author><author><name sortKey="Gibson, Lorna" sort="Gibson, Lorna" uniqKey="Gibson L" first="Lorna" last="Gibson">Lorna Gibson</name><affiliation><nlm:aff id="A74">Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine, London, UK</nlm:aff></affiliation></author><author><name sortKey="Muller Myhsok, Bertram" sort="Muller Myhsok, Bertram" uniqKey="Muller Myhsok B" first="Bertram" last="Müller-Myhsok">Bertram Müller-Myhsok</name><affiliation><nlm:aff id="A142">Statistical Genetics Research Group, Max Planck Institute of Psychiatry, Munich, Germany</nlm:aff></affiliation></author><author><name sortKey="Schmutzler, Rita K" sort="Schmutzler, Rita K" uniqKey="Schmutzler R" first="Rita K" last="Schmutzler">Rita K. Schmutzler</name><affiliation><nlm:aff id="A143">Centre of Hereditary Breast and Ovarian Cancer, University Hospital, Cologne, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A144">Centre of Integrated Oncology, University Hospital, Cologne, Germany</nlm:aff></affiliation></author><author><name sortKey="Hein, Rebecca" sort="Hein, Rebecca" uniqKey="Hein R" first="Rebecca" last="Hein">Rebecca Hein</name><affiliation><nlm:aff id="A18">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A145">PMV (Primärmedizinische Versorgung) Research Group, Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany</nlm:aff></affiliation></author><author><name sortKey="Dahmen, Norbert" sort="Dahmen, Norbert" uniqKey="Dahmen N" first="Norbert" last="Dahmen">Norbert Dahmen</name><affiliation><nlm:aff id="A146">Department of Psychiatry, University of Mainz, Mainz, Germany</nlm:aff></affiliation></author><author><name sortKey="Beckmann, Lars" sort="Beckmann, Lars" uniqKey="Beckmann L" first="Lars" last="Beckmann">Lars Beckmann</name><affiliation><nlm:aff id="A147">Institute for Quality and Efficiency in Health Care (IQWiG), Cologne, Germany</nlm:aff></affiliation></author><author><name sortKey="Aaltonen, Kirsimari" sort="Aaltonen, Kirsimari" uniqKey="Aaltonen K" first="Kirsimari" last="Aaltonen">Kirsimari Aaltonen</name><affiliation><nlm:aff id="A21">Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland</nlm:aff></affiliation><affiliation><nlm:aff id="A91">Department of Clinical Genetics, Helsinki University Central Hospital, Helsinki, Finland</nlm:aff></affiliation><affiliation><nlm:aff id="A92">Department of Oncology, Helsinki University Central Hospital, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Czene, Kamila" sort="Czene, Kamila" uniqKey="Czene K" first="Kamila" last="Czene">Kamila Czene</name><affiliation><nlm:aff id="A27">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</nlm:aff></affiliation></author><author><name sortKey="Irwanto, Astrid" sort="Irwanto, Astrid" uniqKey="Irwanto A" first="Astrid" last="Irwanto">Astrid Irwanto</name><affiliation><nlm:aff id="A148">Human Genetics Division, Genome Institute of Singapore, Singapore</nlm:aff></affiliation></author><author><name sortKey="Liu, Jianjun" sort="Liu, Jianjun" uniqKey="Liu J" first="Jianjun" last="Liu">Jianjun Liu</name><affiliation><nlm:aff id="A148">Human Genetics Division, Genome Institute of Singapore, Singapore</nlm:aff></affiliation></author><author><name sortKey="Turnbull, Clare" sort="Turnbull, Clare" uniqKey="Turnbull C" first="Clare" last="Turnbull">Clare Turnbull</name><affiliation><nlm:aff id="A1">Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, UK</nlm:aff></affiliation></author><author><name sortKey="Rahman, Nazneen" sort="Rahman, Nazneen" uniqKey="Rahman N" first="Nazneen" last="Rahman">Nazneen Rahman</name><affiliation><nlm:aff id="A1">Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, UK</nlm:aff></affiliation></author><author><name sortKey="Meijers Heijboer, Hanne" sort="Meijers Heijboer, Hanne" uniqKey="Meijers Heijboer H" first="Hanne" last="Meijers-Heijboer">Hanne Meijers-Heijboer</name><affiliation><nlm:aff id="A140">Section of Oncogenetics, Department of Clinical Genetics, VU University Medical Center, Amsterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="Andre G" last="Uitterlinden">Andre G. Uitterlinden</name><affiliation><nlm:aff id="A149">Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Rivadeneira, Fernando" sort="Rivadeneira, Fernando" uniqKey="Rivadeneira F" first="Fernando" last="Rivadeneira">Fernando Rivadeneira</name><affiliation><nlm:aff id="A149">Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Olswold, Curtis" sort="Olswold, Curtis" uniqKey="Olswold C" first="Curtis" last="Olswold">Curtis Olswold</name><affiliation><nlm:aff id="A3">Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota, USA</nlm:aff></affiliation></author><author><name sortKey="Slager, Susan" sort="Slager, Susan" uniqKey="Slager S" first="Susan" last="Slager">Susan Slager</name><affiliation><nlm:aff id="A3">Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota, USA</nlm:aff></affiliation></author><author><name sortKey="Pilarski, Robert" sort="Pilarski, Robert" uniqKey="Pilarski R" first="Robert" last="Pilarski">Robert Pilarski</name><affiliation><nlm:aff id="A150">Department of Internal Medicine, James Comprehensive Cancer Center, Ohio State University, Columbus, Ohio, USA</nlm:aff></affiliation></author><author><name sortKey="Ademuyiwa, Foluso" sort="Ademuyiwa, Foluso" uniqKey="Ademuyiwa F" first="Foluso" last="Ademuyiwa">Foluso Ademuyiwa</name><affiliation><nlm:aff id="A151">Roswell Park Cancer Institute, Buffalo, New York, USA</nlm:aff></affiliation></author><author><name sortKey="Konstantopoulou, Irene" sort="Konstantopoulou, Irene" uniqKey="Konstantopoulou I" first="Irene" last="Konstantopoulou">Irene Konstantopoulou</name><affiliation><nlm:aff id="A152">Molecular Diagnostics Laboratory, Institute of Radioisotopes and Radiodiagnostic Products (IRRP), National Centre for Scientific Research Demokritos, Aghia Paraskevi Attikis, Athens, Greece</nlm:aff></affiliation></author><author><name sortKey="Martin, Nicholas G" sort="Martin, Nicholas G" uniqKey="Martin N" first="Nicholas G" last="Martin">Nicholas G. Martin</name><affiliation><nlm:aff id="A153">QIMR GWAS Collective, Queensland Institute of Medical Research, Brisbane, Queensland, Australia</nlm:aff></affiliation></author><author><name sortKey="Montgomery, Grant W" sort="Montgomery, Grant W" uniqKey="Montgomery G" first="Grant W" last="Montgomery">Grant W. Montgomery</name><affiliation><nlm:aff id="A153">QIMR GWAS Collective, Queensland Institute of Medical Research, Brisbane, Queensland, Australia</nlm:aff></affiliation></author><author><name sortKey="Slamon, Dennis J" sort="Slamon, Dennis J" uniqKey="Slamon D" first="Dennis J" last="Slamon">Dennis J. Slamon</name><affiliation><nlm:aff id="A15">Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A154">Department of Medicine, Division of Hematology and Oncology, University of California, Los Angeles, Los Angeles, California, USA</nlm:aff></affiliation></author><author><name sortKey="Rauh, Claudia" sort="Rauh, Claudia" uniqKey="Rauh C" first="Claudia" last="Rauh">Claudia Rauh</name><affiliation><nlm:aff id="A14">Department of Gynecology and Obstetrics, University Breast Center Franconia, University Hospital Erlangen, Erlangen, Germany</nlm:aff></affiliation></author><author><name sortKey="Lux, Michael P" sort="Lux, Michael P" uniqKey="Lux M" first="Michael P" last="Lux">Michael P. Lux</name><affiliation><nlm:aff id="A14">Department of Gynecology and Obstetrics, University Breast Center Franconia, University Hospital Erlangen, Erlangen, Germany</nlm:aff></affiliation></author><author><name sortKey="Jud, Sebastian M" sort="Jud, Sebastian M" uniqKey="Jud S" first="Sebastian M" last="Jud">Sebastian M. Jud</name><affiliation><nlm:aff id="A14">Department of Gynecology and Obstetrics, University Breast Center Franconia, University Hospital Erlangen, Erlangen, Germany</nlm:aff></affiliation></author><author><name sortKey="Bruning, Thomas" sort="Bruning, Thomas" uniqKey="Bruning T" first="Thomas" last="Bruning">Thomas Bruning</name><affiliation><nlm:aff id="A155">Institute for Prevention and Occupational Medicine of the German Social Accident Insurance (IPA), Bochum, Germany</nlm:aff></affiliation></author><author><name sortKey="Weaver, Joellen" sort="Weaver, Joellen" uniqKey="Weaver J" first="Joellen" last="Weaver">Joellen Weaver</name><affiliation><nlm:aff id="A156">Biosample Repository, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA</nlm:aff></affiliation></author><author><name sortKey="Sharma, Priyanka" sort="Sharma, Priyanka" uniqKey="Sharma P" first="Priyanka" last="Sharma">Priyanka Sharma</name><affiliation><nlm:aff id="A157">Division of Hematology and Oncology, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA</nlm:aff></affiliation></author><author><name sortKey="Pathak, Harsh" sort="Pathak, Harsh" uniqKey="Pathak H" first="Harsh" last="Pathak">Harsh Pathak</name><affiliation><nlm:aff id="A20">Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA</nlm:aff></affiliation></author><author><name sortKey="Tapper, Will" sort="Tapper, Will" uniqKey="Tapper W" first="Will" last="Tapper">Will Tapper</name><affiliation><nlm:aff id="A12">Faculty of Medicine, University of Southampton, Southampton, UK</nlm:aff></affiliation></author><author><name sortKey="Gerty, Sue" sort="Gerty, Sue" uniqKey="Gerty S" first="Sue" last="Gerty">Sue Gerty</name><affiliation><nlm:aff id="A12">Faculty of Medicine, University of Southampton, Southampton, UK</nlm:aff></affiliation></author><author><name sortKey="Durcan, Lorraine" sort="Durcan, Lorraine" uniqKey="Durcan L" first="Lorraine" last="Durcan">Lorraine Durcan</name><affiliation><nlm:aff id="A12">Faculty of Medicine, University of Southampton, Southampton, UK</nlm:aff></affiliation></author><author><name sortKey="Trichopoulos, Dimitrios" sort="Trichopoulos, Dimitrios" uniqKey="Trichopoulos D" first="Dimitrios" last="Trichopoulos">Dimitrios Trichopoulos</name><affiliation><nlm:aff id="A4">Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A158">Bureau of Epidemiologic Research, Academy of Athens, Athens, Greece</nlm:aff></affiliation><affiliation><nlm:aff id="A159">Hellenic Health Foundation, Athens, Greece</nlm:aff></affiliation></author><author><name sortKey="Tumino, Rosario" sort="Tumino, Rosario" uniqKey="Tumino R" first="Rosario" last="Tumino">Rosario Tumino</name><affiliation><nlm:aff id="A160">Cancer Registry, Histopathology Unit Civile MPArezzo Hospital, Ragusa, Italy</nlm:aff></affiliation></author><author><name sortKey="Peeters, Petra H" sort="Peeters, Petra H" uniqKey="Peeters P" first="Petra H" last="Peeters">Petra H. Peeters</name><affiliation><nlm:aff id="A161">Julius Center, University Medical Center Utrecht, Utrecht, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Kaaks, Rudolf" sort="Kaaks, Rudolf" uniqKey="Kaaks R" first="Rudolf" last="Kaaks">Rudolf Kaaks</name><affiliation><nlm:aff id="A18">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Campa, Daniele" sort="Campa, Daniele" uniqKey="Campa D" first="Daniele" last="Campa">Daniele Campa</name><affiliation><nlm:aff id="A18">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Canzian, Federico" sort="Canzian, Federico" uniqKey="Canzian F" first="Federico" last="Canzian">Federico Canzian</name><affiliation><nlm:aff id="A18">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name><affiliation><nlm:aff id="A27">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</nlm:aff></affiliation><affiliation><nlm:aff id="A162">Department of Community Medicine, University of Tromsø, Tromsø, Norway</nlm:aff></affiliation><affiliation><nlm:aff id="A164">Cancer Registry of Norway, Oslo, Norway</nlm:aff></affiliation></author><author><name sortKey="Johansson, Mattias" sort="Johansson, Mattias" uniqKey="Johansson M" first="Mattias" last="Johansson">Mattias Johansson</name><affiliation><nlm:aff id="A165">Genetic Epidemiology Group, International Agency for Research on Cancer, World Health Organization, Lyon, France</nlm:aff></affiliation></author><author><name sortKey="Khaw, Kay Tee" sort="Khaw, Kay Tee" uniqKey="Khaw K" first="Kay-Tee" last="Khaw">Kay-Tee Khaw</name><affiliation><nlm:aff id="A166">Clinical Gerontology Unit, University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Travis, Ruth" sort="Travis, Ruth" uniqKey="Travis R" first="Ruth" last="Travis">Ruth Travis</name><affiliation><nlm:aff id="A167">Cancer Epidemiology Unit, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK</nlm:aff></affiliation></author><author><name sortKey="Clavel Chapelon, Francoise" sort="Clavel Chapelon, Francoise" uniqKey="Clavel Chapelon F" first="Françoise" last="Clavel-Chapelon">Françoise Clavel-Chapelon</name><affiliation><nlm:aff id="A33">University Paris–Sud, Unité Mixte de Recherche Scientifique (UMRS) 1018, Villejuif, France</nlm:aff></affiliation><affiliation><nlm:aff id="A34">INSERM (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), Environmental Epidemiology of Cancer, Villejuif, France</nlm:aff></affiliation></author><author><name sortKey="Kolonel, Laurence N" sort="Kolonel, Laurence N" uniqKey="Kolonel L" first="Laurence N" last="Kolonel">Laurence N. Kolonel</name><affiliation><nlm:aff id="A110">Département de Médecine Sociale et Préventive, Département de Santé Environnementale et Santé au Travail, Université de Montréal, Montreal, Quebec, Canada</nlm:aff></affiliation></author><author><name sortKey="Chen, Constance" sort="Chen, Constance" uniqKey="Chen C" first="Constance" last="Chen">Constance Chen</name><affiliation><nlm:aff id="A4">Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA</nlm:aff></affiliation></author><author><name sortKey="Beck, Andy" sort="Beck, Andy" uniqKey="Beck A" first="Andy" last="Beck">Andy Beck</name><affiliation><nlm:aff id="A168">Department of Pathology, Beth Israel DeaconessMedical Center, Boston, Massachusetts, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A169">Department of Pathology, Harvard Medical School, Boston, Massachusetts, USA</nlm:aff></affiliation></author><author><name sortKey="Hankinson, Susan E" sort="Hankinson, Susan E" uniqKey="Hankinson S" first="Susan E" last="Hankinson">Susan E. Hankinson</name><affiliation><nlm:aff id="A170">Division of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst, Massachusetts, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A171">Channing Division of Network Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, USA</nlm:aff></affiliation></author><author><name sortKey="Berg, Christine D" sort="Berg, Christine D" uniqKey="Berg C" first="Christine D" last="Berg">Christine D. Berg</name><affiliation><nlm:aff id="A172">Division of Cancer Prevention, National Cancer Institute, Bethesda, Maryland, USA</nlm:aff></affiliation></author><author><name sortKey="Hoover, Robert N" sort="Hoover, Robert N" uniqKey="Hoover R" first="Robert N" last="Hoover">Robert N. Hoover</name><affiliation><nlm:aff id="A138">Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA</nlm:aff></affiliation></author><author><name sortKey="Lissowska, Jolanta" sort="Lissowska, Jolanta" uniqKey="Lissowska J" first="Jolanta" last="Lissowska">Jolanta Lissowska</name><affiliation><nlm:aff id="A173">Department of Cancer Epidemiology and Prevention, M Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland</nlm:aff></affiliation></author><author><name sortKey="Figueroa, Jonine D" sort="Figueroa, Jonine D" uniqKey="Figueroa J" first="Jonine D" last="Figueroa">Jonine D. Figueroa</name><affiliation><nlm:aff id="A138">Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA</nlm:aff></affiliation></author><author><name sortKey="Chasman, Daniel I" sort="Chasman, Daniel I" uniqKey="Chasman D" first="Daniel I" last="Chasman">Daniel I. Chasman</name><affiliation><nlm:aff id="A11">Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, USA</nlm:aff></affiliation></author><author><name sortKey="Gaudet, Mia M" sort="Gaudet, Mia M" uniqKey="Gaudet M" first="Mia M" last="Gaudet">Mia M. Gaudet</name><affiliation><nlm:aff id="A174">Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, USA</nlm:aff></affiliation></author><author><name sortKey="Diver, W Ryan" sort="Diver, W Ryan" uniqKey="Diver W" first="W Ryan" last="Diver">W Ryan Diver</name><affiliation><nlm:aff id="A174">Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, USA</nlm:aff></affiliation></author><author><name sortKey="Willett, Walter C" sort="Willett, Walter C" uniqKey="Willett W" first="Walter C" last="Willett">Walter C. Willett</name><affiliation><nlm:aff id="A175">Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA</nlm:aff></affiliation></author><author><name sortKey="Hunter, David J" sort="Hunter, David J" uniqKey="Hunter D" first="David J" last="Hunter">David J. Hunter</name><affiliation><nlm:aff id="A4">Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA</nlm:aff></affiliation></author><author><name sortKey="Simard, Jacques" sort="Simard, Jacques" uniqKey="Simard J" first="Jacques" last="Simard">Jacques Simard</name><affiliation><nlm:aff id="A111">Cancer Genomics Laboratory, Centre Hospitalier Universitaire de Québec and Laval University, Quebec City, Quebec, Canada</nlm:aff></affiliation></author><author><name sortKey="Benitez, Javier" sort="Benitez, Javier" uniqKey="Benitez J" first="Javier" last="Benitez">Javier Benitez</name><affiliation><nlm:aff id="A129">Human Genotyping Unit–CEGEN, Human Cancer Genetics Programme, CNIO, Madrid, Spain</nlm:aff></affiliation><affiliation><nlm:aff id="A176">Human Genetics Group, CNIO, Madrid, Spain</nlm:aff></affiliation><affiliation><nlm:aff id="A177">Centro de Investigacion en Red de Enfermedades Raras (CIBERER), Madrid, Spain</nlm:aff></affiliation></author><author><name sortKey="Dunning, Alison M" sort="Dunning, Alison M" uniqKey="Dunning A" first="Alison M" last="Dunning">Alison M. Dunning</name><affiliation><nlm:aff id="A124">Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Sherman, Mark E" sort="Sherman, Mark E" uniqKey="Sherman M" first="Mark E" last="Sherman">Mark E. Sherman</name><affiliation><nlm:aff id="A138">Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA</nlm:aff></affiliation></author><author><name sortKey="Chenevix Trench, Georgia" sort="Chenevix Trench, Georgia" uniqKey="Chenevix Trench G" first="Georgia" last="Chenevix-Trench">Georgia Chenevix-Trench</name><affiliation><nlm:aff id="A178">Department of Genetics, Queensland Institute of Medical Research, Brisbane, Queensland, Australia</nlm:aff></affiliation></author><author><name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J" last="Chanock">Stephen J. Chanock</name><affiliation><nlm:aff id="A138">Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA</nlm:aff></affiliation></author><author><name sortKey="Hall, Per" sort="Hall, Per" uniqKey="Hall P" first="Per" last="Hall">Per Hall</name><affiliation><nlm:aff id="A27">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</nlm:aff></affiliation></author><author><name sortKey="Pharoah, Paul D P" sort="Pharoah, Paul D P" uniqKey="Pharoah P" first="Paul D P" last="Pharoah">Paul D P. Pharoah</name><affiliation><nlm:aff id="A124">Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Vachon, Celine" sort="Vachon, Celine" uniqKey="Vachon C" first="Celine" last="Vachon">Celine Vachon</name><affiliation><nlm:aff id="A3">Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota, USA</nlm:aff></affiliation></author><author><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F" last="Easton">Douglas F. Easton</name><affiliation><nlm:aff id="A5">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Haiman, Christopher A" sort="Haiman, Christopher A" uniqKey="Haiman C" first="Christopher A" last="Haiman">Christopher A. Haiman</name><affiliation><nlm:aff id="A7">Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA</nlm:aff></affiliation></author><author><name sortKey="Kraft, Peter" sort="Kraft, Peter" uniqKey="Kraft P" first="Peter" last="Kraft">Peter Kraft</name><affiliation><nlm:aff id="A4">Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA</nlm:aff></affiliation></author></analytic><series><title level="j">Nature genetics</title><idno type="ISSN">1061-4036</idno><idno type="eISSN">1546-1718</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">Estrogen receptor (ER)-negative tumors represent 20–30% of all breast cancers, with a higher proportion occurring in younger women and women of African ancestry<sup><xref rid="R1" ref-type="bibr">1</xref></sup>. The etiology<sup><xref rid="R2" ref-type="bibr">2</xref></sup> and clinical behavior<sup><xref rid="R3" ref-type="bibr">3</xref></sup> of ER-negative tumors are different from those of tumors expressing ER (ER positive), including differences in genetic predisposition<sup><xref rid="R4" ref-type="bibr">4</xref></sup>. To identify susceptibility loci specific to ER-negative disease, we combined in a meta-analysis 3 genome-wide association studies of 4,193 ER-negative breast cancer cases and 35,194 controls with a series of 40 follow-up studies (6,514 cases and 41,455 controls), genotyped using a custom Illumina array, iCOGS, developed by the Collaborative Oncological Gene-environment Study (COGS). SNPs at four loci, 1q32.1 (<italic>MDM4</italic>, <italic>P</italic> = 2.1 × 10<sup>−12</sup> and <italic>LGR6</italic>, <italic>P</italic> = 1.4 × 10<sup>−8</sup>), 2p24.1 (<italic>P</italic> = 4.6 × 10<sup>−8</sup>) and 16q12.2 (<italic>FTO</italic>, <italic>P</italic> = 4.0 × 10<sup>−8</sup>), were associated with ER-negative but not ER-positive breast cancer (<italic>P</italic> > 0.05). These findings provide further evidence for distinct etiological pathways associated with invasive ER-positive and ER-negative breast cancers.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
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<front><journal-meta><journal-id journal-id-type="nlm-journal-id">9216904</journal-id><journal-id journal-id-type="pubmed-jr-id">2419</journal-id><journal-id journal-id-type="nlm-ta">Nat Genet</journal-id><journal-id journal-id-type="iso-abbrev">Nat. Genet.</journal-id><journal-title-group><journal-title>Nature genetics</journal-title></journal-title-group><issn pub-type="ppub">1061-4036</issn><issn pub-type="epub">1546-1718</issn></journal-meta><article-meta><article-id pub-id-type="pmid">23535733</article-id><article-id pub-id-type="pmc">3771695</article-id><article-id pub-id-type="doi">10.1038/ng.2561</article-id><article-id pub-id-type="manuscript">NIHMS479348</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Genome-wide association studies identify four ER negative–specific breast cancer risk loci</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Garcia-Closas</surname><given-names>Montserrat</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref ref-type="aff" rid="A2">2</xref><xref rid="FN2" ref-type="author-notes">180</xref></contrib><contrib 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rid="A3">3</xref><xref rid="FN3" ref-type="author-notes">181</xref></contrib><contrib contrib-type="author"><name><surname>Easton</surname><given-names>Douglas F</given-names></name><xref ref-type="aff" rid="A5">5</xref><xref rid="FN3" ref-type="author-notes">181</xref></contrib><contrib contrib-type="author"><name><surname>Haiman</surname><given-names>Christopher A</given-names></name><xref ref-type="aff" rid="A7">7</xref><xref rid="FN3" ref-type="author-notes">181</xref></contrib><contrib contrib-type="author"><name><surname>Kraft</surname><given-names>Peter</given-names></name><xref ref-type="aff" rid="A4">4</xref><xref rid="FN3" ref-type="author-notes">181</xref></contrib></contrib-group><aff id="A1"><label>1</label>Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, UK</aff><aff id="A2"><label>2</label>Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK</aff><aff id="A3"><label>3</label>Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota, USA</aff><aff id="A4"><label>4</label>Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA</aff><aff id="A5"><label>5</label>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK</aff><aff id="A6"><label>6</label>Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands</aff><aff id="A7"><label>7</label>Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA</aff><aff id="A8"><label>8</label>School of Public Health, Imperial College, London, UK</aff><aff id="A9"><label>9</label>Kaiser Permanente, Institute for Health Research, Denver, Colorado, USA</aff><aff id="A10"><label>10</label>Epidemiology Program, Cancer Research Center, University of Hawaii, Honolulu, Hawaii, USA</aff><aff id="A11"><label>11</label>Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, USA</aff><aff id="A12"><label>12</label>Faculty of Medicine, University of Southampton, Southampton, UK</aff><aff id="A13"><label>13</label>Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA</aff><aff id="A14"><label>14</label>Department of Gynecology and Obstetrics, University Breast Center Franconia, University Hospital Erlangen, Erlangen, Germany</aff><aff id="A15"><label>15</label>Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA</aff><aff id="A16"><label>16</label>Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany</aff><aff id="A17"><label>17</label>University of Tübingen, Tübingen, Germany</aff><aff id="A18"><label>18</label>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</aff><aff id="A19"><label>19</label>Australian Breast Cancer Tissue Bank, University of Sydney at the Westmead Millennium Institute, Westmead, New South Wales, Australia</aff><aff id="A20"><label>20</label>Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA</aff><aff id="A21"><label>21</label>Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland</aff><aff id="A22"><label>22</label>Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia</aff><aff id="A23"><label>23</label>School of Population Health, The University of Melbourne, Melbourne, Victoria, Australia</aff><aff id="A24"><label>24</label>Cancer Research UK/Yorkshire Cancer Research Sheffield Cancer Research Centre, Department of Oncology, University of Sheffield, Sheffield, UK</aff><aff id="A25"><label>25</label>Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Victoria, Australia</aff><aff id="A26"><label>26</label>Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK</aff><aff id="A27"><label>27</label>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</aff><aff id="A28"><label>28</label>Copenhagen General Population Study, Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark</aff><aff id="A29"><label>29</label>Vesalius Research Center (VRC), VIB, Leuven, Belgium</aff><aff id="A30"><label>30</label>Department of Oncology, University of Leuven, Leuven, Belgium</aff><aff id="A31"><label>31</label>Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada</aff><aff id="A32"><label>32</label>Ontario Cancer Genetics Network, Fred A. Litwin Center for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada</aff><aff id="A33"><label>33</label>University Paris–Sud, Unité Mixte de Recherche Scientifique (UMRS) 1018, Villejuif, France</aff><aff id="A34"><label>34</label>INSERM (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), Environmental Epidemiology of Cancer, Villejuif, France</aff><aff id="A35"><label>35</label>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</aff><aff id="A36"><label>36</label>Molecular Epidemiology Group, DKFZ, Heidelberg, Germany</aff><aff id="A37"><label>37</label>Division of Cancer Studies, National Institute for Health Research (NIHR) Comprehensive Biomedical Research Centre, Guy’s & St. Thomas’ National Health Service (NHS) Foundation Trust in partnership with King’s College London, London, UK</aff><aff id="A38"><label>38</label>Department of Medical Oncology, Erasmus University Medical Center–Daniel Den Hoed Cancer Center, Rotterdam, The Netherlands</aff><aff id="A39"><label>39</label>Laboratory of Cancer Genetics and Tumor Biology, Department of Clinical Genetics, Biocenter Oulu, University of Oulu, Oulu University Hospital, Oulu, Finland</aff><aff id="A40"><label>40</label>Division of Clinical Epidemiology and Aging Research, DKFZ, Heidelberg, Germany</aff><aff id="A41"><label>41</label>Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland</aff><aff id="A42"><label>42</label>School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, Kuopio, Finland</aff><aff id="A43"><label>43</label>Biocenter Kuopio, Cancer Center of Eastern Finland, University of Eastern Finland, Kuopio, Finland</aff><aff id="A44"><label>44</label>Molecular Genetics of Breast Cancer, DKFZ, Heidelberg, Germany</aff><aff id="A45"><label>45</label>Division for Gynaecological Tumor Genetics, Clinic of Gynaecology and Obstetrics, Technische Universität München, Munich, Germany</aff><aff id="A46"><label>46</label>Division of Gynaecology and Obstetrics, Technische Universität München, Munich, Germany</aff><aff id="A47"><label>47</label>Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden</aff><aff id="A48"><label>48</label>Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA</aff><aff id="A49"><label>49</label>Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands</aff><aff id="A50"><label>50</label>Department of Pathology, Erasmus University Medical Center, Rotterdam, The Netherlands</aff><aff id="A51"><label>51</label>Department of Medicine, McGill University, Montreal, Quebec, Canada</aff><aff id="A52"><label>52</label>Division of Clinical Epidemiology, McGill University Health Centre, Royal Victoria Hospital, Montreal, Quebec, Canada</aff><aff id="A53"><label>53</label>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland</aff><aff id="A54"><label>54</label>Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo, Norway</aff><aff id="A55"><label>55</label>Faculty of Medicine (Faculty Division Ahus), Universitetet i Oslo, Oslo, Norway</aff><aff id="A56"><label>56</label>Department of Epidemiology, University of California–Irvine, Irvine, California, USA</aff><aff id="A57"><label>57</label>Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany</aff><aff id="A58"><label>58</label>Warwick Medical School, Warwick University, Coventry, UK</aff><aff id="A59"><label>59</label>Institute of Population Health, University of Manchester, Manchester, UK</aff><aff id="A60"><label>60</label>Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan</aff><aff id="A61"><label>61</label>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy</aff><aff id="A62"><label>62</label>IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy</aff><aff id="A63"><label>63</label>Cancer Research Initiatives Foundation, Sime Darby Medical Centre, Subang Jaya, University Malaya Cancer Research Institute, University Malaya, Kuala Lumpur, Malaysia</aff><aff id="A64"><label>64</label>Breast Cancer Research Unit, University Malaya Cancer Research Institute, University Malaya, Kuala Lumpur, Malaysia</aff><aff id="A65"><label>65</label>International Epidemiology Institute, Rockville, Maryland, USA</aff><aff id="A66"><label>66</label>Seoul National University College of Medicine, Seoul, Korea</aff><aff id="A67"><label>67</label>Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore</aff><aff id="A68"><label>68</label>Saw Swee Hock School of Public Health, National University of Singapore, Singapore</aff><aff id="A69"><label>69</label>National Cancer Institute, Bangkok, Thailand</aff><aff id="A70"><label>70</label>Colleague of Public Health, China Medical University, Taichong, Taiwan</aff><aff id="A71"><label>71</label>Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan</aff><aff id="A72"><label>72</label>Department of Pathology, The University of Melbourne, Melbourne, Victoria, Australia</aff><aff id="A73"><label>73</label>Ministry of Public Health, Bangkok, Thailand</aff><aff id="A74"><label>74</label>Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine, London, UK</aff><aff id="A75"><label>75</label>Institute of Human Genetics, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany</aff><aff id="A76"><label>76</label>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</aff><aff id="A77"><label>77</label>Oxford Biomedical Research Centre, University of Oxford, Oxford, UK</aff><aff id="A78"><label>78</label>Department of Surgery, Clinical Science Institute, University Hospital and National University of Ireland, Galway, Ireland</aff><aff id="A79"><label>79</label>National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany</aff><aff id="A80"><label>80</label>INSERM, Université Paris Sorbonne Cité, UMRS 775, Paris, France</aff><aff id="A81"><label>81</label>Centre Eugène Marquis, Department of Medical Oncology, Rennes, France</aff><aff id="A82"><label>82</label>Department of Breast Surgery, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Denmark</aff><aff id="A83"><label>83</label>Genetic & Molecular Epidemiology Group, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), Madrid, Spain</aff><aff id="A84"><label>84</label>Servicio de Cirugía General y Especialidades, Hospital Monte Naranco, Oviedo, Spain</aff><aff id="A85"><label>85</label>Servicio de Anatomía Patológica, Hospital Monte Naranco, Oviedo, Spain</aff><aff id="A86"><label>86</label>Saarland Cancer Registry, Saarbrücken, Germany</aff><aff id="A87"><label>87</label>Institute of Human Genetics, Technische Universität München, Munich, Germany</aff><aff id="A88"><label>88</label>Institute of Human Genetics, Helmholtz Zentrum München–German Research Center for Environmental Health, Neuherberg, Germany</aff><aff id="A89"><label>89</label>Department of Internal Medicine, Evangelische Kliniken Bonn, Johanniter Krankenhaus, Bonn, Germany</aff><aff id="A90"><label>90</label>A list of members is provided in the<xref rid="SD1" ref-type="supplementary-material">Supplementary Note</xref></aff><aff id="A91"><label>91</label>Department of Clinical Genetics, Helsinki University Central Hospital, Helsinki, Finland</aff><aff id="A92"><label>92</label>Department of Oncology, Helsinki University Central Hospital, Helsinki, Finland</aff><aff id="A93"><label>93</label>Department of Breast Oncology, Aichi Cancer Center Hospital, Nagoya, Japan</aff><aff id="A94"><label>94</label>Department of Pathology and Molecular Diagnostics, Aichi Cancer Center Hospital, Nagoya, Japan</aff><aff id="A95"><label>95</label>N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus</aff><aff id="A96"><label>96</label>Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden</aff><aff id="A97"><label>97</label>Cancer Center, Kuopio University Hospital, Kuopio, Finland</aff><aff id="A98"><label>98</label>Western Sydney Local Health District, Westmead Millennium Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia</aff><aff id="A99"><label>99</label>Nepean Blue Mountains Local Health District, Westmead Millennium Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia</aff><aff id="A100"><label>100</label>Multidisciplinary Breast Center, University Hospital Gasthuisberg, Department of Oncology, University of Leuven, Leuven, Belgium</aff><aff id="A101"><label>101</label>Department of Cancer Epidemiology/Clinical Cancer Registry, University Clinic Hamburg-Eppendorf, Hamburg, Germany</aff><aff id="A102"><label>102</label>Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg, Germany</aff><aff id="A103"><label>103</label>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS INT, Milan, Italy</aff><aff id="A104"><label>104</label>Department of Experimental Oncology, Istituto Europeo di Oncologia, Milan, Italy</aff><aff id="A105"><label>105</label>Cogentech Cancer Genetic Test Laboratory, Milan, Italy</aff><aff id="A106"><label>106</label>Department of Laboratory Medicine and Pathology, Division of Experimental Pathology, Mayo Clinic, Rochester, Minnesota, USA</aff><aff id="A107"><label>107</label>Department of Anatomical Pathology, The Alfred Hospital, Melbourne, Victoria, Australia</aff><aff id="A108"><label>108</label>Department of Urology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA</aff><aff id="A109"><label>109</label>Department of Radiation Oncology, Hannover Medical School, Hannover, Germany</aff><aff id="A110"><label>110</label>Département de Médecine Sociale et Préventive, Département de Santé Environnementale et Santé au Travail, Université de Montréal, Montreal, Quebec, Canada</aff><aff id="A111"><label>111</label>Cancer Genomics Laboratory, Centre Hospitalier Universitaire de Québec and Laval University, Quebec City, Quebec, Canada</aff><aff id="A112"><label>112</label>Singapore Eye Research Institute, National University of Singapore, Singapore</aff><aff id="A113"><label>113</label>Department of Oncology, Oulu University Hospital, University of Oulu, Oulu, Finland</aff><aff id="A114"><label>114</label>Department of Pathology, Oulu University Hospital, University of Oulu, Oulu, Finland</aff><aff id="A115"><label>115</label>Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada</aff><aff id="A116"><label>116</label>Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada</aff><aff id="A117"><label>117</label>Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada</aff><aff id="A118"><label>118</label>Department of Laboratory Medicine, Keenan Research Centre of the Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, Ontario, Canada</aff><aff id="A119"><label>119</label>Department of Surgical Oncology, Leiden University Medical Center, Leiden, The Netherlands</aff><aff id="A120"><label>120</label>Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands</aff><aff id="A121"><label>121</label>Shanghai Center for Disease Control and Prevention, Shanghai, China</aff><aff id="A122"><label>122</label>Department of Epidemiology, Shanghai Cancer Institute, Shanghai, China</aff><aff id="A123"><label>123</label>Academic Unit of Pathology, Department of Neuroscience, University of Sheffield, Sheffield, UK</aff><aff id="A124"><label>124</label>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK</aff><aff id="A125"><label>125</label>Department of Surgery, National University Health System, Singapore</aff><aff id="A126"><label>126</label>Taiwan Biobank, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan</aff><aff id="A127"><label>127</label>Department of Surgery, Tri-Service General Hospital, Taipei, Taiwan</aff><aff id="A128"><label>128</label>McGill University and Génome Québec Innovation Centre, Montreal, Québec, Canada</aff><aff id="A129"><label>129</label>Human Genotyping Unit–CEGEN, Human Cancer Genetics Programme, CNIO, Madrid, Spain</aff><aff id="A130"><label>130</label>Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, New York, USA</aff><aff id="A131"><label>131</label>The Cancer Institute of New Jersey, New Brunswick, New Jersey, USA</aff><aff id="A132"><label>132</label>Cancer Prevention Institute of California, Fremont, California, USA</aff><aff id="A133"><label>133</label>Department of Health Research and Policy, Division of Epidemiology, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California, USA</aff><aff id="A134"><label>134</label>Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida, USA</aff><aff id="A135"><label>135</label>Department of Epidemiology and Public Health, University of Miami Miller School of Medicine, Miami, Florida, USA</aff><aff id="A136"><label>136</label>Division of Cancer Etiology, Department of Population Science, Beckman Research Institute, City of Hope, Duarte, California, USA</aff><aff id="A137"><label>137</label>Department of Pathology, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA</aff><aff id="A138"><label>138</label>Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA</aff><aff id="A139"><label>139</label>Department of Epidemiology, Gillings School of Global Public Health, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, Chapel Hill, North Carolina, USA</aff><aff id="A140"><label>140</label>Section of Oncogenetics, Department of Clinical Genetics, VU University Medical Center, Amsterdam, The Netherlands</aff><aff id="A141"><label>141</label>Genetic Epidemiology Laboratory, Department of Pathology, The University of Melbourne, Melbourne, Victoria, Australia</aff><aff id="A142"><label>142</label>Statistical Genetics Research Group, Max Planck Institute of Psychiatry, Munich, Germany</aff><aff id="A143"><label>143</label>Centre of Hereditary Breast and Ovarian Cancer, University Hospital, Cologne, Germany</aff><aff id="A144"><label>144</label>Centre of Integrated Oncology, University Hospital, Cologne, Germany</aff><aff id="A145"><label>145</label>PMV (Primärmedizinische Versorgung) Research Group, Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany</aff><aff id="A146"><label>146</label>Department of Psychiatry, University of Mainz, Mainz, Germany</aff><aff id="A147"><label>147</label>Institute for Quality and Efficiency in Health Care (IQWiG), Cologne, Germany</aff><aff id="A148"><label>148</label>Human Genetics Division, Genome Institute of Singapore, Singapore</aff><aff id="A149"><label>149</label>Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands</aff><aff id="A150"><label>150</label>Department of Internal Medicine, James Comprehensive Cancer Center, Ohio State University, Columbus, Ohio, USA</aff><aff id="A151"><label>151</label>Roswell Park Cancer Institute, Buffalo, New York, USA</aff><aff id="A152"><label>152</label>Molecular Diagnostics Laboratory, Institute of Radioisotopes and Radiodiagnostic Products (IRRP), National Centre for Scientific Research Demokritos, Aghia Paraskevi Attikis, Athens, Greece</aff><aff id="A153"><label>153</label>QIMR GWAS Collective, Queensland Institute of Medical Research, Brisbane, Queensland, Australia</aff><aff id="A154"><label>154</label>Department of Medicine, Division of Hematology and Oncology, University of California, Los Angeles, Los Angeles, California, USA</aff><aff id="A155"><label>155</label>Institute for Prevention and Occupational Medicine of the German Social Accident Insurance (IPA), Bochum, Germany</aff><aff id="A156"><label>156</label>Biosample Repository, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA</aff><aff id="A157"><label>157</label>Division of Hematology and Oncology, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA</aff><aff id="A158"><label>158</label>Bureau of Epidemiologic Research, Academy of Athens, Athens, Greece</aff><aff id="A159"><label>159</label>Hellenic Health Foundation, Athens, Greece</aff><aff id="A160"><label>160</label>Cancer Registry, Histopathology Unit Civile MPArezzo Hospital, Ragusa, Italy</aff><aff id="A161"><label>161</label>Julius Center, University Medical Center Utrecht, Utrecht, The Netherlands</aff><aff id="A162"><label>162</label>Department of Community Medicine, University of Tromsø, Tromsø, Norway</aff><aff id="A163"><label>163</label>Folkhälsan Research Cancer Centre, Helsinki, Finland</aff><aff id="A164"><label>164</label>Cancer Registry of Norway, Oslo, Norway</aff><aff id="A165"><label>165</label>Genetic Epidemiology Group, International Agency for Research on Cancer, World Health Organization, Lyon, France</aff><aff id="A166"><label>166</label>Clinical Gerontology Unit, University of Cambridge, Cambridge, UK</aff><aff id="A167"><label>167</label>Cancer Epidemiology Unit, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK</aff><aff id="A168"><label>168</label>Department of Pathology, Beth Israel DeaconessMedical Center, Boston, Massachusetts, USA</aff><aff id="A169"><label>169</label>Department of Pathology, Harvard Medical School, Boston, Massachusetts, USA</aff><aff id="A170"><label>170</label>Division of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst, Massachusetts, USA</aff><aff id="A171"><label>171</label>Channing Division of Network Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, USA</aff><aff id="A172"><label>172</label>Division of Cancer Prevention, National Cancer Institute, Bethesda, Maryland, USA</aff><aff id="A173"><label>173</label>Department of Cancer Epidemiology and Prevention, M Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland</aff><aff id="A174"><label>174</label>Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, USA</aff><aff id="A175"><label>175</label>Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA</aff><aff id="A176"><label>176</label>Human Genetics Group, CNIO, Madrid, Spain</aff><aff id="A177"><label>177</label>Centro de Investigacion en Red de Enfermedades Raras (CIBERER), Madrid, Spain</aff><aff id="A178"><label>178</label>Department of Genetics, Queensland Institute of Medical Research, Brisbane, Queensland, Australia</aff><author-notes><corresp id="FN3">Correspondence should be addressed to M.G.-C. (<email>montse.garciaclosas@icr.ac.uk</email>)</corresp><fn id="FN1"><label>179</label><p>Deceased.</p></fn><fn id="FN2"><label>180</label><p>These authors contributed equally to this work.</p></fn><fn id="FN10"><label>181</label><p>These authors jointly directed this work.</p></fn></author-notes><pub-date pub-type="nihms-submitted"><day>26</day><month>8</month><year>2013</year></pub-date><pub-date pub-type="ppub"><month>4</month><year>2013</year></pub-date><pub-date pub-type="pmc-release"><day>01</day><month>4</month><year>2014</year></pub-date><volume>45</volume><issue>4</issue><fpage>392</fpage><lpage>398e2</lpage><permissions><copyright-statement>© 2013 Nature America, Inc. All rights reserved.</copyright-statement><copyright-year>2013</copyright-year></permissions><abstract><p id="P1">Estrogen receptor (ER)-negative tumors represent 20–30% of all breast cancers, with a higher proportion occurring in younger women and women of African ancestry<sup><xref rid="R1" ref-type="bibr">1</xref></sup>. The etiology<sup><xref rid="R2" ref-type="bibr">2</xref></sup> and clinical behavior<sup><xref rid="R3" ref-type="bibr">3</xref></sup> of ER-negative tumors are different from those of tumors expressing ER (ER positive), including differences in genetic predisposition<sup><xref rid="R4" ref-type="bibr">4</xref></sup>. To identify susceptibility loci specific to ER-negative disease, we combined in a meta-analysis 3 genome-wide association studies of 4,193 ER-negative breast cancer cases and 35,194 controls with a series of 40 follow-up studies (6,514 cases and 41,455 controls), genotyped using a custom Illumina array, iCOGS, developed by the Collaborative Oncological Gene-environment Study (COGS). SNPs at four loci, 1q32.1 (<italic>MDM4</italic>, <italic>P</italic> = 2.1 × 10<sup>−12</sup> and <italic>LGR6</italic>, <italic>P</italic> = 1.4 × 10<sup>−8</sup>), 2p24.1 (<italic>P</italic> = 4.6 × 10<sup>−8</sup>) and 16q12.2 (<italic>FTO</italic>, <italic>P</italic> = 4.0 × 10<sup>−8</sup>), were associated with ER-negative but not ER-positive breast cancer (<italic>P</italic> > 0.05). These findings provide further evidence for distinct etiological pathways associated with invasive ER-positive and ER-negative breast cancers.</p></abstract><funding-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>U01 CA098758 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>U01 CA069638 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>U01 CA069638 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>U01 CA069631 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>U01 CA069446 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>U01 CA069417 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>R37 CA070867 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>R37 CA054281 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>R01 CA148667 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>R01 CA136924 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>R01 CA132839 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>R01 CA128978 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>R01 CA122340 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>R01 CA100598 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>R01 CA100374 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>R01 CA077305 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>R01 CA073629 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>R01 CA064277 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>R01 CA063464 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>R01 CA058860 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>P50 CA116201 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>K07 CA092044 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>K05 CA136967 || CA</award-id></award-group></funding-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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