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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Identification of common variants associated with human hippocampal and intracranial volumes</title><author><name sortKey="Stein, Jason L" sort="Stein, Jason L" uniqKey="Stein J" first="Jason L" last="Stein">Jason L. Stein</name><affiliation><nlm:aff id="A1">Laboratory of Neuro Imaging, David Geffen School of Medicine, University of California, Los Angeles, California, USA.</nlm:aff></affiliation></author><author><name sortKey="Medland, Sarah E" sort="Medland, Sarah E" uniqKey="Medland S" first="Sarah E" last="Medland">Sarah E. Medland</name><affiliation><nlm:aff id="A2">Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland, Australia.</nlm:aff></affiliation><affiliation><nlm:aff id="A3">Quantitative Genetics Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland, Australia.</nlm:aff></affiliation><affiliation><nlm:aff id="A4">Broad Institute of Harvard University and MIT, Cambridge, Massachusetts, USA.</nlm:aff></affiliation></author><author><name sortKey="Vasquez, Alejandro Arias" sort="Vasquez, Alejandro Arias" uniqKey="Vasquez A" first="Alejandro Arias" last="Vasquez">Alejandro Arias Vasquez</name><affiliation><nlm:aff id="A5">Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A6">Department of Psychiatry, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A7">Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Hibar, Derrek P" sort="Hibar, Derrek P" uniqKey="Hibar D" first="Derrek P" last="Hibar">Derrek P. Hibar</name><affiliation><nlm:aff id="A1">Laboratory of Neuro Imaging, David Geffen School of Medicine, University of California, Los Angeles, California, USA.</nlm:aff></affiliation></author><author><name sortKey="Senstad, Rudy E" sort="Senstad, Rudy E" uniqKey="Senstad R" first="Rudy E" last="Senstad">Rudy E. Senstad</name><affiliation><nlm:aff id="A1">Laboratory of Neuro Imaging, David Geffen School of Medicine, University of California, Los Angeles, California, USA.</nlm:aff></affiliation></author><author><name sortKey="Winkler, Anderson M" sort="Winkler, Anderson M" uniqKey="Winkler A" first="Anderson M" last="Winkler">Anderson M. Winkler</name><affiliation><nlm:aff id="A8">Olin Neuropsychiatry Research Center, Institute of Living, Hartford Hospital, Hartford, Connecticut, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A9">Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA.</nlm:aff></affiliation></author><author><name sortKey="Toro, Roberto" sort="Toro, Roberto" uniqKey="Toro R" first="Roberto" last="Toro">Roberto Toro</name><affiliation><nlm:aff id="A10">Laboratory of Human Genetics and Cognitive Functions, Institut Pasteur, Paris, France.</nlm:aff></affiliation><affiliation><nlm:aff id="A11">Centre Nationale de Recherche Scientifique (CNRS) Unité de Recherche Associée (URA) 2182 Genes, Synapses and Cognition, Institut Pasteur, Paris, France.</nlm:aff></affiliation><affiliation><nlm:aff id="A12">Department of Neuroscience, Université Paris Diderot, Sorbonne Paris Cité, Paris, France.</nlm:aff></affiliation></author><author><name sortKey="Appel, Katja" sort="Appel, Katja" uniqKey="Appel K" first="Katja" last="Appel">Katja Appel</name><affiliation><nlm:aff id="A13">Department of Psychiatry and Psychotherapy, University of Greifswald, Greifswald, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A14">Institute of Psychology, Department of Clinical Psychology and Psychotherapy, University of Heidelberg, Heidelberg, Germany.</nlm:aff></affiliation></author><author><name sortKey="Bartecek, Richard" sort="Bartecek, Richard" uniqKey="Bartecek R" first="Richard" last="Bartecek">Richard Bartecek</name><affiliation><nlm:aff id="A15">Department of Psychiatry, Rudolf Magnus Institute, University Medical Center Utrecht, Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Bergmann, Rjan" sort="Bergmann, Rjan" uniqKey="Bergmann " first=" Rjan" last="Bergmann"> Rjan Bergmann</name><affiliation><nlm:aff id="A16">Institute of Clinical Medicine, University of Oslo, Oslo, Norway.</nlm:aff></affiliation></author><author><name sortKey="Bernard, Manon" sort="Bernard, Manon" uniqKey="Bernard M" first="Manon" last="Bernard">Manon Bernard</name><affiliation><nlm:aff id="A17">The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.</nlm:aff></affiliation></author><author><name sortKey="Brown, Andrew A" sort="Brown, Andrew A" uniqKey="Brown A" first="Andrew A" last="Brown">Andrew A. Brown</name><affiliation><nlm:aff id="A16">Institute of Clinical Medicine, University of Oslo, Oslo, Norway.</nlm:aff></affiliation><affiliation><nlm:aff id="A18">Institute of Basic Medical Sciences, Department of Biostatistics, University of Oslo, Oslo, Norway.</nlm:aff></affiliation></author><author><name sortKey="Cannon, Dara M" sort="Cannon, Dara M" uniqKey="Cannon D" first="Dara M" last="Cannon">Dara M. Cannon</name><affiliation><nlm:aff id="A19">Clinical Neuroimaging Laboratory, Department of Anatomy, National University of Ireland Galway, Galway, Ireland.</nlm:aff></affiliation></author><author><name sortKey="Chakravarty, M Mallar" sort="Chakravarty, M Mallar" uniqKey="Chakravarty M" first="M Mallar" last="Chakravarty">M Mallar Chakravarty</name><affiliation><nlm:aff id="A21">Rotman Research Institute, University of Toronto, Toronto, Ontario, Canada.</nlm:aff></affiliation></author><author><name sortKey="Christoforou, Andrea" sort="Christoforou, Andrea" uniqKey="Christoforou A" first="Andrea" last="Christoforou">Andrea Christoforou</name><affiliation><nlm:aff id="A22">Dr Einar Martens Research Group for Biological Psychiatry, Department of Clinical Medicine, University of Bergen, Bergen, Norway.</nlm:aff></affiliation><affiliation><nlm:aff id="A23">Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway.</nlm:aff></affiliation></author><author><name sortKey="Domin, Martin" sort="Domin, Martin" uniqKey="Domin M" first="Martin" last="Domin">Martin Domin</name><affiliation><nlm:aff id="A24">Department of Diagnostic Radiology and Neuroradiology, University of Greifswald, Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Grimm, Oliver" sort="Grimm, Oliver" uniqKey="Grimm O" first="Oliver" last="Grimm">Oliver Grimm</name><affiliation><nlm:aff id="A25">Central Institute of Mental Health, University of Heidelberg–Medical Faculty Mannheim, Mannheim, Germany.</nlm:aff></affiliation></author><author><name sortKey="Hollinshead, Marisa" sort="Hollinshead, Marisa" uniqKey="Hollinshead M" first="Marisa" last="Hollinshead">Marisa Hollinshead</name><affiliation><nlm:aff id="A26">Department of Psychology, Center for Brain Science, Harvard University, Cambridge, Massachusetts, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A27">Howard Hughes Medical Institute, Cambridge, Massachusetts, USA.</nlm:aff></affiliation></author><author><name sortKey="Holmes, Avram J" sort="Holmes, Avram J" uniqKey="Holmes A" first="Avram J" last="Holmes">Avram J. Holmes</name><affiliation><nlm:aff id="A26">Department of Psychology, Center for Brain Science, Harvard University, Cambridge, Massachusetts, USA.</nlm:aff></affiliation></author><author><name sortKey="Homuth, Georg" sort="Homuth, Georg" uniqKey="Homuth G" first="Georg" last="Homuth">Georg Homuth</name><affiliation><nlm:aff id="A28">Interfaculty Institute for Genetics and Functional Genomics, University of Greifswald, Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Hottenga, Jouke Jan" sort="Hottenga, Jouke Jan" uniqKey="Hottenga J" first="Jouke-Jan" last="Hottenga">Jouke-Jan Hottenga</name><affiliation><nlm:aff id="A29">Department of Biological Psychology, Neuroscience Campus Amsterdam, VU University, Amsterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Langan, Camilla" sort="Langan, Camilla" uniqKey="Langan C" first="Camilla" last="Langan">Camilla Langan</name><affiliation><nlm:aff id="A20">Clinical Neuroimaging Laboratory, Department of Psychiatry, National University of Ireland Galway, Galway, Ireland.</nlm:aff></affiliation></author><author><name sortKey="Lopez, Lorna M" sort="Lopez, Lorna M" uniqKey="Lopez L" first="Lorna M" last="Lopez">Lorna M. Lopez</name><affiliation><nlm:aff id="A30">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A31">Department of Psychology, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Hansell, Narelle K" sort="Hansell, Narelle K" uniqKey="Hansell N" first="Narelle K" last="Hansell">Narelle K. Hansell</name><affiliation><nlm:aff id="A2">Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland, Australia.</nlm:aff></affiliation></author><author><name sortKey="Hwang, Kristy S" sort="Hwang, Kristy S" uniqKey="Hwang K" first="Kristy S" last="Hwang">Kristy S. Hwang</name><affiliation><nlm:aff id="A1">Laboratory of Neuro Imaging, David Geffen School of Medicine, University of California, Los Angeles, California, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A32">Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, California, USA.</nlm:aff></affiliation></author><author><name sortKey="Kim, Sungeun" sort="Kim, Sungeun" uniqKey="Kim S" first="Sungeun" last="Kim">Sungeun Kim</name><affiliation><nlm:aff id="A33">Department of Radiology and Imaging Sciences, Center for Neuroimaging, Indiana University School of Medicine, Indianapolis, Indiana, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A34">Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, Indiana, USA.</nlm:aff></affiliation></author><author><name sortKey="Laje, Gonzalo" sort="Laje, Gonzalo" uniqKey="Laje G" first="Gonzalo" last="Laje">Gonzalo Laje</name><affiliation><nlm:aff id="A35">Mood and Anxiety Disorders Section, Human Genetics Branch, Intramural Research Program, National Institute of Mental Health (NIMH), US National Institutes of Health (NIH), US Department of Health and Human Services, Bethesda, Maryland, USA.</nlm:aff></affiliation></author><author><name sortKey="Lee, Phil H" sort="Lee, Phil H" uniqKey="Lee P" first="Phil H" last="Lee">Phil H. Lee</name><affiliation><nlm:aff id="A36">Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A37">Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff></affiliation></author><author><name sortKey="Liu, Xinmin" sort="Liu, Xinmin" uniqKey="Liu X" first="Xinmin" last="Liu">Xinmin Liu</name><affiliation><nlm:aff id="A35">Mood and Anxiety Disorders Section, Human Genetics Branch, Intramural Research Program, National Institute of Mental Health (NIMH), US National Institutes of Health (NIH), US Department of Health and Human Services, Bethesda, Maryland, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A38">Taub Institute for Research on Alzheimer Disease and the Aging Brain, Columbia University Medical Center, New York, New York, USA.</nlm:aff></affiliation></author><author><name sortKey="Loth, Eva" sort="Loth, Eva" uniqKey="Loth E" first="Eva" last="Loth">Eva Loth</name><affiliation><nlm:aff id="A39">Medical Research Council (MRC)–Social, Genetic and Developmental Psychiatry (SGDP) Centre, Institute of Psychiatry, King’s College London, London, UK.</nlm:aff></affiliation></author><author><name sortKey="Lourdusamy, Anbarasu" sort="Lourdusamy, Anbarasu" uniqKey="Lourdusamy A" first="Anbarasu" last="Lourdusamy">Anbarasu Lourdusamy</name><affiliation><nlm:aff id="A39">Medical Research Council (MRC)–Social, Genetic and Developmental Psychiatry (SGDP) Centre, Institute of Psychiatry, King’s College London, London, UK.</nlm:aff></affiliation></author><author><name sortKey="Mattingsdal, Morten" sort="Mattingsdal, Morten" uniqKey="Mattingsdal M" first="Morten" last="Mattingsdal">Morten Mattingsdal</name><affiliation><nlm:aff id="A16">Institute of Clinical Medicine, University of Oslo, Oslo, Norway.</nlm:aff></affiliation><affiliation><nlm:aff id="A40">Research Unit, Sørlandet Hospital, Kristiansand, Norway.</nlm:aff></affiliation></author><author><name sortKey="Mohnke, Sebastian" sort="Mohnke, Sebastian" uniqKey="Mohnke S" first="Sebastian" last="Mohnke">Sebastian Mohnke</name><affiliation><nlm:aff id="A41">Department of Psychiatry and Psychotherapy, Charité-Universitaetsmedizin Berlin, Campus Mitte, Berlin, Germany.</nlm:aff></affiliation></author><author><name sortKey="Maniega, Susana Mu Oz" sort="Maniega, Susana Mu Oz" uniqKey="Maniega S" first="Susana Mu Oz" last="Maniega">Susana Mu Oz Maniega</name><affiliation><nlm:aff id="A30">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A42">Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) Collaboration, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A43">Brain Research Imaging Centre, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Nho, Kwangsik" sort="Nho, Kwangsik" uniqKey="Nho K" first="Kwangsik" last="Nho">Kwangsik Nho</name><affiliation><nlm:aff id="A33">Department of Radiology and Imaging Sciences, Center for Neuroimaging, Indiana University School of Medicine, Indianapolis, Indiana, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A44">Division of Medical Informatics, Regenstrief Institute, Indianapolis, Indiana, USA.</nlm:aff></affiliation></author><author><name sortKey="Nugent, Allison C" sort="Nugent, Allison C" uniqKey="Nugent A" first="Allison C" last="Nugent">Allison C. Nugent</name><affiliation><nlm:aff id="A45">Section on Neuroimaging in Mood and Anxiety Disorders, Intramural Research Program, NIMH, NIH, US Department of Health and Human Services, Bethesda, Maryland, USA.</nlm:aff></affiliation></author><author><name sortKey="O Rien, Carol" sort="O Rien, Carol" uniqKey="O Rien C" first="Carol" last="O Rien">Carol O Rien</name><affiliation><nlm:aff id="A46">Neuropsychiatric Genetics Research Group, Department of Psychiatry, Institute for Molecular Medicine, Trinity College, Dublin, Ireland.</nlm:aff></affiliation><affiliation><nlm:aff id="A47">Trinity College Institute of Neuroscience, Trinity College, Dublin, Ireland.</nlm:aff></affiliation></author><author><name sortKey="Papmeyer, Martina" sort="Papmeyer, Martina" uniqKey="Papmeyer M" first="Martina" last="Papmeyer">Martina Papmeyer</name><affiliation><nlm:aff id="A48">Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Putz, Benno" sort="Putz, Benno" uniqKey="Putz B" first="Benno" last="Pütz">Benno Pütz</name><affiliation><nlm:aff id="A49">Max Planck Institute of Psychiatry, Munich, Germany.</nlm:aff></affiliation></author><author><name sortKey="Ramasamy, Adaikalavan" sort="Ramasamy, Adaikalavan" uniqKey="Ramasamy A" first="Adaikalavan" last="Ramasamy">Adaikalavan Ramasamy</name><affiliation><nlm:aff id="A50">Department of Medical & Molecular Genetics, King’s College London, London, UK.</nlm:aff></affiliation></author><author><name sortKey="Rasmussen, Jerod" sort="Rasmussen, Jerod" uniqKey="Rasmussen J" first="Jerod" last="Rasmussen">Jerod Rasmussen</name><affiliation><nlm:aff id="A51">Department of Psychiatry and Human Behavior, University of California, Irvine, California, USA.</nlm:aff></affiliation></author><author><name sortKey="Rijpkema, Mark" sort="Rijpkema, Mark" uniqKey="Rijpkema M" first="Mark" last="Rijpkema">Mark Rijpkema</name><affiliation><nlm:aff id="A7">Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A52">Donders Centre for Cognitive Neuroimaging, Radboud University Nijmegen, Nijmegen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Risacher, Shannon L" sort="Risacher, Shannon L" uniqKey="Risacher S" first="Shannon L" last="Risacher">Shannon L. Risacher</name><affiliation><nlm:aff id="A33">Department of Radiology and Imaging Sciences, Center for Neuroimaging, Indiana University School of Medicine, Indianapolis, Indiana, USA.</nlm:aff></affiliation></author><author><name sortKey="Roddey, J Cooper" sort="Roddey, J Cooper" uniqKey="Roddey J" first="J Cooper" last="Roddey">J Cooper Roddey</name><affiliation><nlm:aff id="A53">Department of Neurosciences, University of California, San Diego, La Jolla, California, USA.</nlm:aff></affiliation></author><author><name sortKey="Rose, Emma J" sort="Rose, Emma J" uniqKey="Rose E" first="Emma J" last="Rose">Emma J. Rose</name><affiliation><nlm:aff id="A46">Neuropsychiatric Genetics Research Group, Department of Psychiatry, Institute for Molecular Medicine, Trinity College, Dublin, Ireland.</nlm:aff></affiliation><affiliation><nlm:aff id="A47">Trinity College Institute of Neuroscience, Trinity College, Dublin, Ireland.</nlm:aff></affiliation></author><author><name sortKey="Ryten, Mina" sort="Ryten, Mina" uniqKey="Ryten M" first="Mina" last="Ryten">Mina Ryten</name><affiliation><nlm:aff id="A54">Department of Molecular Neuroscience, University College London, London, UK.</nlm:aff></affiliation></author><author><name sortKey="Shen, Li" sort="Shen, Li" uniqKey="Shen L" first="Li" last="Shen">Li Shen</name><affiliation><nlm:aff id="A33">Department of Radiology and Imaging Sciences, Center for Neuroimaging, Indiana University School of Medicine, Indianapolis, Indiana, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A34">Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, Indiana, USA.</nlm:aff></affiliation></author><author><name sortKey="Sprooten, Emma" sort="Sprooten, Emma" uniqKey="Sprooten E" first="Emma" last="Sprooten">Emma Sprooten</name><affiliation><nlm:aff id="A48">Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Strengman, Eric" sort="Strengman, Eric" uniqKey="Strengman E" first="Eric" last="Strengman">Eric Strengman</name><affiliation><nlm:aff id="A55">Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A56">Rudolf Magnus Institute, University Medical Center Utrecht, Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Teumer, Alexander" sort="Teumer, Alexander" uniqKey="Teumer A" first="Alexander" last="Teumer">Alexander Teumer</name><affiliation><nlm:aff id="A28">Interfaculty Institute for Genetics and Functional Genomics, University of Greifswald, Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Trabzuni, Daniah" sort="Trabzuni, Daniah" uniqKey="Trabzuni D" first="Daniah" last="Trabzuni">Daniah Trabzuni</name><affiliation><nlm:aff id="A54">Department of Molecular Neuroscience, University College London, London, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A57">Department of Genetics, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.</nlm:aff></affiliation></author><author><name sortKey="Turner, Jessica" sort="Turner, Jessica" uniqKey="Turner J" first="Jessica" last="Turner">Jessica Turner</name><affiliation><nlm:aff id="A58">Mind Research Network, Albuquerque, New Mexico, USA.</nlm:aff></affiliation></author><author><name sortKey="Van Eijk, Kristel" sort="Van Eijk, Kristel" uniqKey="Van Eijk K" first="Kristel" last="Van Eijk">Kristel Van Eijk</name><affiliation><nlm:aff id="A55">Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A56">Rudolf Magnus Institute, University Medical Center Utrecht, Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Van Erp, Theo G M" sort="Van Erp, Theo G M" uniqKey="Van Erp T" first="Theo G M" last="Van Erp">Theo G M. Van Erp</name><affiliation><nlm:aff id="A51">Department of Psychiatry and Human Behavior, University of California, Irvine, California, USA.</nlm:aff></affiliation></author><author><name sortKey="Van Tol, Marie Jose" sort="Van Tol, Marie Jose" uniqKey="Van Tol M" first="Marie-Jose" last="Van Tol">Marie-Jose Van Tol</name><affiliation><nlm:aff id="A59">Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A60">Leiden Institute for Brain and Cognition, Leiden University, Leiden, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A61">Behavioural and Cognitive Neuroscience Neuroimaging Center, University Medical Center Groningen, Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Wittfeld, Katharina" sort="Wittfeld, Katharina" uniqKey="Wittfeld K" first="Katharina" last="Wittfeld">Katharina Wittfeld</name><affiliation><nlm:aff id="A13">Department of Psychiatry and Psychotherapy, University of Greifswald, Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Wolf, Christiane" sort="Wolf, Christiane" uniqKey="Wolf C" first="Christiane" last="Wolf">Christiane Wolf</name><affiliation><nlm:aff id="A49">Max Planck Institute of Psychiatry, Munich, Germany.</nlm:aff></affiliation></author><author><name sortKey="Woudstra, Saskia" sort="Woudstra, Saskia" uniqKey="Woudstra S" first="Saskia" last="Woudstra">Saskia Woudstra</name><affiliation><nlm:aff id="A62">Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Aleman, Andre" sort="Aleman, Andre" uniqKey="Aleman A" first="Andre" last="Aleman">Andre Aleman</name><affiliation><nlm:aff id="A61">Behavioural and Cognitive Neuroscience Neuroimaging Center, University Medical Center Groningen, Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Alhusaini, Saud" sort="Alhusaini, Saud" uniqKey="Alhusaini S" first="Saud" last="Alhusaini">Saud Alhusaini</name><affiliation><nlm:aff id="A63">Department of Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.</nlm:aff></affiliation></author><author><name sortKey="Almasy, Laura" sort="Almasy, Laura" uniqKey="Almasy L" first="Laura" last="Almasy">Laura Almasy</name><affiliation><nlm:aff id="A64">Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA.</nlm:aff></affiliation></author><author><name sortKey="Binder, Elisabeth B" sort="Binder, Elisabeth B" uniqKey="Binder E" first="Elisabeth B" last="Binder">Elisabeth B. Binder</name><affiliation><nlm:aff id="A49">Max Planck Institute of Psychiatry, Munich, Germany.</nlm:aff></affiliation></author><author><name sortKey="Brohawn, David G" sort="Brohawn, David G" uniqKey="Brohawn D" first="David G" last="Brohawn">David G. Brohawn</name><affiliation><nlm:aff id="A36">Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff></affiliation></author><author><name sortKey="Cantor, Rita M" sort="Cantor, Rita M" uniqKey="Cantor R" first="Rita M" last="Cantor">Rita M. Cantor</name><affiliation><nlm:aff id="A65">Center for Neurobehavioral Genetics, University of California, Los Angeles, USA.</nlm:aff></affiliation></author><author><name sortKey="Carless, Melanie A" sort="Carless, Melanie A" uniqKey="Carless M" first="Melanie A" last="Carless">Melanie A. Carless</name><affiliation><nlm:aff id="A64">Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA.</nlm:aff></affiliation></author><author><name sortKey="Corvin, Aiden" sort="Corvin, Aiden" uniqKey="Corvin A" first="Aiden" last="Corvin">Aiden Corvin</name><affiliation><nlm:aff id="A46">Neuropsychiatric Genetics Research Group, Department of Psychiatry, Institute for Molecular Medicine, Trinity College, Dublin, Ireland.</nlm:aff></affiliation><affiliation><nlm:aff id="A47">Trinity College Institute of Neuroscience, Trinity College, Dublin, Ireland.</nlm:aff></affiliation></author><author><name sortKey="Czisch, Michael" sort="Czisch, Michael" uniqKey="Czisch M" first="Michael" last="Czisch">Michael Czisch</name><affiliation><nlm:aff id="A49">Max Planck Institute of Psychiatry, Munich, Germany.</nlm:aff></affiliation></author><author><name sortKey="Curran, Joanne E" sort="Curran, Joanne E" uniqKey="Curran J" first="Joanne E" last="Curran">Joanne E. Curran</name><affiliation><nlm:aff id="A64">Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA.</nlm:aff></affiliation></author><author><name sortKey="Davies, Gail" sort="Davies, Gail" uniqKey="Davies G" first="Gail" last="Davies">Gail Davies</name><affiliation><nlm:aff id="A31">Department of Psychology, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="De Almeida, Marcio A A" sort="De Almeida, Marcio A A" uniqKey="De Almeida M" first="Marcio A A" last="De Almeida">Marcio A A. De Almeida</name><affiliation><nlm:aff id="A64">Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA.</nlm:aff></affiliation></author><author><name sortKey="Delanty, Norman" sort="Delanty, Norman" uniqKey="Delanty N" first="Norman" last="Delanty">Norman Delanty</name><affiliation><nlm:aff id="A63">Department of Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.</nlm:aff></affiliation><affiliation><nlm:aff id="A66">Division of Neurology, Beaumont Hospital, Dublin, Ireland.</nlm:aff></affiliation></author><author><name sortKey="Depondt, Chantal" sort="Depondt, Chantal" uniqKey="Depondt C" first="Chantal" last="Depondt">Chantal Depondt</name><affiliation><nlm:aff id="A67">Department of Neurology, Hopital Erasme, Universite Libre de Bruxelles, Brussels, Belgium.</nlm:aff></affiliation></author><author><name sortKey="Duggirala, Ravi" sort="Duggirala, Ravi" uniqKey="Duggirala R" first="Ravi" last="Duggirala">Ravi Duggirala</name><affiliation><nlm:aff id="A64">Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA.</nlm:aff></affiliation></author><author><name sortKey="Dyer, Thomas D" sort="Dyer, Thomas D" uniqKey="Dyer T" first="Thomas D" last="Dyer">Thomas D. Dyer</name><affiliation><nlm:aff id="A64">Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA.</nlm:aff></affiliation></author><author><name sortKey="Erk, Susanne" sort="Erk, Susanne" uniqKey="Erk S" first="Susanne" last="Erk">Susanne Erk</name><affiliation><nlm:aff id="A41">Department of Psychiatry and Psychotherapy, Charité-Universitaetsmedizin Berlin, Campus Mitte, Berlin, Germany.</nlm:aff></affiliation></author><author><name sortKey="Fagerness, Jesen" sort="Fagerness, Jesen" uniqKey="Fagerness J" first="Jesen" last="Fagerness">Jesen Fagerness</name><affiliation><nlm:aff id="A36">Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff></affiliation></author><author><name sortKey="Fox, Peter T" sort="Fox, Peter T" uniqKey="Fox P" first="Peter T" last="Fox">Peter T. Fox</name><affiliation><nlm:aff id="A69">Research Imaging Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.</nlm:aff></affiliation></author><author><name sortKey="Freimer, Nelson B" sort="Freimer, Nelson B" uniqKey="Freimer N" first="Nelson B" last="Freimer">Nelson B. Freimer</name><affiliation><nlm:aff id="A65">Center for Neurobehavioral Genetics, University of California, Los Angeles, USA.</nlm:aff></affiliation></author><author><name sortKey="Gill, Michael" sort="Gill, Michael" uniqKey="Gill M" first="Michael" last="Gill">Michael Gill</name><affiliation><nlm:aff id="A46">Neuropsychiatric Genetics Research Group, Department of Psychiatry, Institute for Molecular Medicine, Trinity College, Dublin, Ireland.</nlm:aff></affiliation><affiliation><nlm:aff id="A47">Trinity College Institute of Neuroscience, Trinity College, Dublin, Ireland.</nlm:aff></affiliation></author><author><name sortKey="Goring, Harald H H" sort="Goring, Harald H H" uniqKey="Goring H" first="Harald H H" last="Göring">Harald H H. Göring</name><affiliation><nlm:aff id="A64">Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA.</nlm:aff></affiliation></author><author><name sortKey="Hagler, Donald J" sort="Hagler, Donald J" uniqKey="Hagler D" first="Donald J" last="Hagler">Donald J. Hagler</name><affiliation><nlm:aff id="A70">Department of Radiology, University of California, San Diego, La Jolla, California, USA.</nlm:aff></affiliation></author><author><name sortKey="Hoehn, David" sort="Hoehn, David" uniqKey="Hoehn D" first="David" last="Hoehn">David Hoehn</name><affiliation><nlm:aff id="A49">Max Planck Institute of Psychiatry, Munich, Germany.</nlm:aff></affiliation></author><author><name sortKey="Holsboer, Florian" sort="Holsboer, Florian" uniqKey="Holsboer F" first="Florian" last="Holsboer">Florian Holsboer</name><affiliation><nlm:aff id="A49">Max Planck Institute of Psychiatry, Munich, Germany.</nlm:aff></affiliation></author><author><name sortKey="Hoogman, Martine" sort="Hoogman, Martine" uniqKey="Hoogman M" first="Martine" last="Hoogman">Martine Hoogman</name><affiliation><nlm:aff id="A5">Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A7">Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A71">Department of Cognitive Neuroscience, Radboud University Nijmegen Medical Centre, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A72">Max Planck Institute for Psycholinguistics, Nijmegen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Hosten, Norbert" sort="Hosten, Norbert" uniqKey="Hosten N" first="Norbert" last="Hosten">Norbert Hosten</name><affiliation><nlm:aff id="A24">Department of Diagnostic Radiology and Neuroradiology, University of Greifswald, Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Jahanshad, Neda" sort="Jahanshad, Neda" uniqKey="Jahanshad N" first="Neda" last="Jahanshad">Neda Jahanshad</name><affiliation><nlm:aff id="A1">Laboratory of Neuro Imaging, David Geffen School of Medicine, University of California, Los Angeles, California, USA.</nlm:aff></affiliation></author><author><name sortKey="Johnson, Matthew P" sort="Johnson, Matthew P" uniqKey="Johnson M" first="Matthew P" last="Johnson">Matthew P. Johnson</name><affiliation><nlm:aff id="A64">Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA.</nlm:aff></affiliation></author><author><name sortKey="Kasperaviciute, Dalia" sort="Kasperaviciute, Dalia" uniqKey="Kasperaviciute D" first="Dalia" last="Kasperaviciute">Dalia Kasperaviciute</name><affiliation><nlm:aff id="A73">Department of Clinical and Experimental Epilepsy, University College London, Institute of Neurology, London, UK.</nlm:aff></affiliation></author><author><name sortKey="Kent, Jack W" sort="Kent, Jack W" uniqKey="Kent J" first="Jack W" last="Kent">Jack W. Kent</name><affiliation><nlm:aff id="A64">Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA.</nlm:aff></affiliation></author><author><name sortKey="Kochunov, Peter" sort="Kochunov, Peter" uniqKey="Kochunov P" first="Peter" last="Kochunov">Peter Kochunov</name><affiliation><nlm:aff id="A69">Research Imaging Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A74">Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, Maryland, USA.</nlm:aff></affiliation></author><author><name sortKey="Lancaster, Jack L" sort="Lancaster, Jack L" uniqKey="Lancaster J" first="Jack L" last="Lancaster">Jack L. Lancaster</name><affiliation><nlm:aff id="A69">Research Imaging Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.</nlm:aff></affiliation></author><author><name sortKey="Lawrie, Stephen M" sort="Lawrie, Stephen M" uniqKey="Lawrie S" first="Stephen M" last="Lawrie">Stephen M. Lawrie</name><affiliation><nlm:aff id="A48">Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Liewald, David C" sort="Liewald, David C" uniqKey="Liewald D" first="David C" last="Liewald">David C. Liewald</name><affiliation><nlm:aff id="A30">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Mandl, Rene" sort="Mandl, Rene" uniqKey="Mandl R" first="René" last="Mandl">René Mandl</name><affiliation><nlm:aff id="A15">Department of Psychiatry, Rudolf Magnus Institute, University Medical Center Utrecht, Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Matarin, Mar" sort="Matarin, Mar" uniqKey="Matarin M" first="Mar" last="Matarin">Mar Matarin</name><affiliation><nlm:aff id="A73">Department of Clinical and Experimental Epilepsy, University College London, Institute of Neurology, London, UK.</nlm:aff></affiliation></author><author><name sortKey="Mattheisen, Manuel" sort="Mattheisen, Manuel" uniqKey="Mattheisen M" first="Manuel" last="Mattheisen">Manuel Mattheisen</name><affiliation><nlm:aff id="A75">Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A76">Institute of Human Genetics, University of Bonn, Bonn, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A77">Institute for Genomic Mathematics, University of Bonn, Bonn, Germany.</nlm:aff></affiliation></author><author><name sortKey="Meisenzahl, Eva" sort="Meisenzahl, Eva" uniqKey="Meisenzahl E" first="Eva" last="Meisenzahl">Eva Meisenzahl</name><affiliation><nlm:aff id="A78">Department of Psychiatry, Ludwig-Maximilians-University (LMU), Munich, Germany.</nlm:aff></affiliation></author><author><name sortKey="Melle, Ingrid" sort="Melle, Ingrid" uniqKey="Melle I" first="Ingrid" last="Melle">Ingrid Melle</name><affiliation><nlm:aff id="A16">Institute of Clinical Medicine, University of Oslo, Oslo, Norway.</nlm:aff></affiliation><affiliation><nlm:aff id="A79">Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.</nlm:aff></affiliation></author><author><name sortKey="Moses, Eric K" sort="Moses, Eric K" uniqKey="Moses E" first="Eric K" last="Moses">Eric K. Moses</name><affiliation><nlm:aff id="A64">Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA.</nlm:aff></affiliation></author><author><name sortKey="Muhleisen, Thomas W" sort="Muhleisen, Thomas W" uniqKey="Muhleisen T" first="Thomas W" last="Mühleisen">Thomas W. Mühleisen</name><affiliation><nlm:aff id="A75">Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A76">Institute of Human Genetics, University of Bonn, Bonn, Germany.</nlm:aff></affiliation></author><author><name sortKey="Nauck, Matthias" sort="Nauck, Matthias" uniqKey="Nauck M" first="Matthias" last="Nauck">Matthias Nauck</name><affiliation><nlm:aff id="A80">Institute of Clinical Chemistry and Laboratory Medicine, University of Greifswald, Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Nothen, Markus M" sort="Nothen, Markus M" uniqKey="Nothen M" first="Markus M" last="Nöthen">Markus M. Nöthen</name><affiliation><nlm:aff id="A75">Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A76">Institute of Human Genetics, University of Bonn, Bonn, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A81">German Center for Neurodegenerative Disorders (DZNE), Bonn, Germany.</nlm:aff></affiliation></author><author><name sortKey="Olvera, Rene L" sort="Olvera, Rene L" uniqKey="Olvera R" first="Rene L" last="Olvera">Rene L. Olvera</name><affiliation><nlm:aff id="A82">Department of Psychiatry, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.</nlm:aff></affiliation></author><author><name sortKey="Pandolfo, Massimo" sort="Pandolfo, Massimo" uniqKey="Pandolfo M" first="Massimo" last="Pandolfo">Massimo Pandolfo</name><affiliation><nlm:aff id="A67">Department of Neurology, Hopital Erasme, Universite Libre de Bruxelles, Brussels, Belgium.</nlm:aff></affiliation></author><author><name sortKey="Pike, G Bruce" sort="Pike, G Bruce" uniqKey="Pike G" first="G Bruce" last="Pike">G Bruce Pike</name><affiliation><nlm:aff id="A83">Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.</nlm:aff></affiliation></author><author><name sortKey="Puls, Ralf" sort="Puls, Ralf" uniqKey="Puls R" first="Ralf" last="Puls">Ralf Puls</name><affiliation><nlm:aff id="A24">Department of Diagnostic Radiology and Neuroradiology, University of Greifswald, Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Reinvang, Ivar" sort="Reinvang, Ivar" uniqKey="Reinvang I" first="Ivar" last="Reinvang">Ivar Reinvang</name><affiliation><nlm:aff id="A84">Center for the Study of Human Cognition, Department of Psychology, University of Oslo, Oslo, Norway.</nlm:aff></affiliation><affiliation><nlm:aff id="A85">Centre for Advanced Study, Oslo, Norway.</nlm:aff></affiliation></author><author><name sortKey="Renteria, Miguel E" sort="Renteria, Miguel E" uniqKey="Renteria M" first="Miguel E" last="Rentería">Miguel E. Rentería</name><affiliation><nlm:aff id="A2">Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland, Australia.</nlm:aff></affiliation><affiliation><nlm:aff id="A86">School of Psychology, University of Queensland, Brisbane, Queensland, Australia.</nlm:aff></affiliation></author><author><name sortKey="Rietschel, Marcella" sort="Rietschel, Marcella" uniqKey="Rietschel M" first="Marcella" last="Rietschel">Marcella Rietschel</name><affiliation><nlm:aff id="A25">Central Institute of Mental Health, University of Heidelberg–Medical Faculty Mannheim, Mannheim, Germany.</nlm:aff></affiliation></author><author><name sortKey="Roffman, Joshua L" sort="Roffman, Joshua L" uniqKey="Roffman J" first="Joshua L" last="Roffman">Joshua L. Roffman</name><affiliation><nlm:aff id="A37">Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff></affiliation></author><author><name sortKey="Royle, Natalie A" sort="Royle, Natalie A" uniqKey="Royle N" first="Natalie A" last="Royle">Natalie A. Royle</name><affiliation><nlm:aff id="A30">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A42">Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) Collaboration, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A43">Brain Research Imaging Centre, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Rujescu, Dan" sort="Rujescu, Dan" uniqKey="Rujescu D" first="Dan" last="Rujescu">Dan Rujescu</name><affiliation><nlm:aff id="A78">Department of Psychiatry, Ludwig-Maximilians-University (LMU), Munich, Germany.</nlm:aff></affiliation></author><author><name sortKey="Savitz, Jonathan" sort="Savitz, Jonathan" uniqKey="Savitz J" first="Jonathan" last="Savitz">Jonathan Savitz</name><affiliation><nlm:aff id="A45">Section on Neuroimaging in Mood and Anxiety Disorders, Intramural Research Program, NIMH, NIH, US Department of Health and Human Services, Bethesda, Maryland, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A87">Laureate Institute for Brain Research, Tulsa, Oklahoma, USA.</nlm:aff></affiliation></author><author><name sortKey="Schnack, Hugo G" sort="Schnack, Hugo G" uniqKey="Schnack H" first="Hugo G" last="Schnack">Hugo G. Schnack</name><affiliation><nlm:aff id="A15">Department of Psychiatry, Rudolf Magnus Institute, University Medical Center Utrecht, Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Schnell, Knut" sort="Schnell, Knut" uniqKey="Schnell K" first="Knut" last="Schnell">Knut Schnell</name><affiliation><nlm:aff id="A88">Department of General Psychiatry, Heidelberg University Hospital, University of Heidelberg, Heidelberg, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A89">Department of Psychiatry, Division of Medical Psychology, Bonn, Germany.</nlm:aff></affiliation></author><author><name sortKey="Seiferth, Nina" sort="Seiferth, Nina" uniqKey="Seiferth N" first="Nina" last="Seiferth">Nina Seiferth</name><affiliation><nlm:aff id="A41">Department of Psychiatry and Psychotherapy, Charité-Universitaetsmedizin Berlin, Campus Mitte, Berlin, Germany.</nlm:aff></affiliation></author><author><name sortKey="Smith, Colin" sort="Smith, Colin" uniqKey="Smith C" first="Colin" last="Smith">Colin Smith</name><affiliation><nlm:aff id="A90">The MRC Sudden Death Tissue Bank in Edinburgh, Department of Pathology, University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Steen, Vidar M" sort="Steen, Vidar M" uniqKey="Steen V" first="Vidar M" last="Steen">Vidar M. Steen</name><affiliation><nlm:aff id="A22">Dr Einar Martens Research Group for Biological Psychiatry, Department of Clinical Medicine, University of Bergen, Bergen, Norway.</nlm:aff></affiliation><affiliation><nlm:aff id="A23">Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway.</nlm:aff></affiliation></author><author><name sortKey="Valdes Hernandez, Maria C" sort="Valdes Hernandez, Maria C" uniqKey="Valdes Hernandez M" first="Maria C" last="Valdés Hernández">Maria C. Valdés Hernández</name><affiliation><nlm:aff id="A30">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A42">Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) Collaboration, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A43">Brain Research Imaging Centre, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Van Den Heuvel, Martijn" sort="Van Den Heuvel, Martijn" uniqKey="Van Den Heuvel M" first="Martijn" last="Van Den Heuvel">Martijn Van Den Heuvel</name><affiliation><nlm:aff id="A15">Department of Psychiatry, Rudolf Magnus Institute, University Medical Center Utrecht, Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Van Der Wee, Nic J" sort="Van Der Wee, Nic J" uniqKey="Van Der Wee N" first="Nic J" last="Van Der Wee">Nic J. Van Der Wee</name><affiliation><nlm:aff id="A59">Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A60">Leiden Institute for Brain and Cognition, Leiden University, Leiden, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Van Haren, Neeltje E M" sort="Van Haren, Neeltje E M" uniqKey="Van Haren N" first="Neeltje E M" last="Van Haren">Neeltje E M. Van Haren</name><affiliation><nlm:aff id="A15">Department of Psychiatry, Rudolf Magnus Institute, University Medical Center Utrecht, Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Veltman, Joris A" sort="Veltman, Joris A" uniqKey="Veltman J" first="Joris A" last="Veltman">Joris A. Veltman</name><affiliation><nlm:aff id="A5">Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Volzke, Henry" sort="Volzke, Henry" uniqKey="Volzke H" first="Henry" last="Völzke">Henry Völzke</name><affiliation><nlm:aff id="A91">Institute for Community Medicine, University of Greifswald, Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Walker, Robert" sort="Walker, Robert" uniqKey="Walker R" first="Robert" last="Walker">Robert Walker</name><affiliation><nlm:aff id="A90">The MRC Sudden Death Tissue Bank in Edinburgh, Department of Pathology, University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Westlye, Lars T" sort="Westlye, Lars T" uniqKey="Westlye L" first="Lars T" last="Westlye">Lars T. Westlye</name><affiliation><nlm:aff id="A84">Center for the Study of Human Cognition, Department of Psychology, University of Oslo, Oslo, Norway.</nlm:aff></affiliation></author><author><name sortKey="Whelan, Christopher D" sort="Whelan, Christopher D" uniqKey="Whelan C" first="Christopher D" last="Whelan">Christopher D. Whelan</name><affiliation><nlm:aff id="A63">Department of Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.</nlm:aff></affiliation></author><author><name sortKey="Agartz, Ingrid" sort="Agartz, Ingrid" uniqKey="Agartz I" first="Ingrid" last="Agartz">Ingrid Agartz</name><affiliation><nlm:aff id="A16">Institute of Clinical Medicine, University of Oslo, Oslo, Norway.</nlm:aff></affiliation><affiliation><nlm:aff id="A92">Department of Research and Development, Diakonhjemmet Hospital, Oslo, Norway.</nlm:aff></affiliation></author><author><name sortKey="Boomsma, Dorret I" sort="Boomsma, Dorret I" uniqKey="Boomsma D" first="Dorret I" last="Boomsma">Dorret I. Boomsma</name><affiliation><nlm:aff id="A29">Department of Biological Psychology, Neuroscience Campus Amsterdam, VU University, Amsterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Cavalleri, Gianpiero L" sort="Cavalleri, Gianpiero L" uniqKey="Cavalleri G" first="Gianpiero L" last="Cavalleri">Gianpiero L. Cavalleri</name><affiliation><nlm:aff id="A63">Department of Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.</nlm:aff></affiliation></author><author><name sortKey="Dale, Anders M" sort="Dale, Anders M" uniqKey="Dale A" first="Anders M" last="Dale">Anders M. Dale</name><affiliation><nlm:aff id="A53">Department of Neurosciences, University of California, San Diego, La Jolla, California, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A70">Department of Radiology, University of California, San Diego, La Jolla, California, USA.</nlm:aff></affiliation></author><author><name sortKey="Djurovic, Srdjan" sort="Djurovic, Srdjan" uniqKey="Djurovic S" first="Srdjan" last="Djurovic">Srdjan Djurovic</name><affiliation><nlm:aff id="A16">Institute of Clinical Medicine, University of Oslo, Oslo, Norway.</nlm:aff></affiliation><affiliation><nlm:aff id="A93">Department of Medical Genetics, Oslo University Hospital, Oslo, Norway.</nlm:aff></affiliation></author><author><name sortKey="Drevets, Wayne C" sort="Drevets, Wayne C" uniqKey="Drevets W" first="Wayne C" last="Drevets">Wayne C. Drevets</name><affiliation><nlm:aff id="A45">Section on Neuroimaging in Mood and Anxiety Disorders, Intramural Research Program, NIMH, NIH, US Department of Health and Human Services, Bethesda, Maryland, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A87">Laureate Institute for Brain Research, Tulsa, Oklahoma, USA.</nlm:aff></affiliation></author><author><name sortKey="Hagoort, Peter" sort="Hagoort, Peter" uniqKey="Hagoort P" first="Peter" last="Hagoort">Peter Hagoort</name><affiliation><nlm:aff id="A7">Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A52">Donders Centre for Cognitive Neuroimaging, Radboud University Nijmegen, Nijmegen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A72">Max Planck Institute for Psycholinguistics, Nijmegen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Hall, Jeremy" sort="Hall, Jeremy" uniqKey="Hall J" first="Jeremy" last="Hall">Jeremy Hall</name><affiliation><nlm:aff id="A48">Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Heinz, Andreas" sort="Heinz, Andreas" uniqKey="Heinz A" first="Andreas" last="Heinz">Andreas Heinz</name><affiliation><nlm:aff id="A41">Department of Psychiatry and Psychotherapy, Charité-Universitaetsmedizin Berlin, Campus Mitte, Berlin, Germany.</nlm:aff></affiliation></author><author><name sortKey="Jack, Clifford R" sort="Jack, Clifford R" uniqKey="Jack C" first="Clifford R" last="Jack">Clifford R. Jack</name><affiliation><nlm:aff id="A94">Aging and Dementia Imaging Research Laboratory, Department of Radiology, Mayo Clinic and Foundation, Rochester, Minnesota, USA.</nlm:aff></affiliation></author><author><name sortKey="Foroud, Tatiana M" sort="Foroud, Tatiana M" uniqKey="Foroud T" first="Tatiana M" last="Foroud">Tatiana M. Foroud</name><affiliation><nlm:aff id="A34">Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, Indiana, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A95">Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA.</nlm:aff></affiliation></author><author><name sortKey="Le Hellard, Stephanie" sort="Le Hellard, Stephanie" uniqKey="Le Hellard S" first="Stephanie" last="Le Hellard">Stephanie Le Hellard</name><affiliation><nlm:aff id="A22">Dr Einar Martens Research Group for Biological Psychiatry, Department of Clinical Medicine, University of Bergen, Bergen, Norway.</nlm:aff></affiliation><affiliation><nlm:aff id="A23">Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway.</nlm:aff></affiliation></author><author><name sortKey="Macciardi, Fabio" sort="Macciardi, Fabio" uniqKey="Macciardi F" first="Fabio" last="Macciardi">Fabio Macciardi</name><affiliation><nlm:aff id="A51">Department of Psychiatry and Human Behavior, University of California, Irvine, California, USA.</nlm:aff></affiliation></author><author><name sortKey="Montgomery, Grant W" sort="Montgomery, Grant W" uniqKey="Montgomery G" first="Grant W" last="Montgomery">Grant W. Montgomery</name><affiliation><nlm:aff id="A2">Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland, Australia.</nlm:aff></affiliation></author><author><name sortKey="Poline, Jean Baptiste" sort="Poline, Jean Baptiste" uniqKey="Poline J" first="Jean Baptiste" last="Poline">Jean Baptiste Poline</name><affiliation><nlm:aff id="A96">Neurospin, Institut d’Imagerie Biomédicale (I2BM), Commissariat à l’Energie Atomique, Gif-sur-Yvette, France.</nlm:aff></affiliation></author><author><name sortKey="Porteous, David J" sort="Porteous, David J" uniqKey="Porteous D" first="David J" last="Porteous">David J. Porteous</name><affiliation><nlm:aff id="A30">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A97">Medical Genetics Section, Molecular Medicine Centre, Institute of Genetics and Molecular Medicine, The University of Edinburgh, Western General Hospital, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Sisodiya, Sanjay M" sort="Sisodiya, Sanjay M" uniqKey="Sisodiya S" first="Sanjay M" last="Sisodiya">Sanjay M. Sisodiya</name><affiliation><nlm:aff id="A73">Department of Clinical and Experimental Epilepsy, University College London, Institute of Neurology, London, UK.</nlm:aff></affiliation></author><author><name sortKey="Starr, John M" sort="Starr, John M" uniqKey="Starr J" first="John M" last="Starr">John M. Starr</name><affiliation><nlm:aff id="A30">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A98">Geriatric Medicine Unit, The University of Edinburgh, Royal Victoria Hospital, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Sussmann, Jessika" sort="Sussmann, Jessika" uniqKey="Sussmann J" first="Jessika" last="Sussmann">Jessika Sussmann</name><affiliation><nlm:aff id="A48">Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Toga, Arthur W" sort="Toga, Arthur W" uniqKey="Toga A" first="Arthur W" last="Toga">Arthur W. Toga</name><affiliation><nlm:aff id="A1">Laboratory of Neuro Imaging, David Geffen School of Medicine, University of California, Los Angeles, California, USA.</nlm:aff></affiliation></author><author><name sortKey="Veltman, Dick J" sort="Veltman, Dick J" uniqKey="Veltman D" first="Dick J" last="Veltman">Dick J. Veltman</name><affiliation><nlm:aff id="A62">Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Walter, Henrik" sort="Walter, Henrik" uniqKey="Walter H" first="Henrik" last="Walter">Henrik Walter</name><affiliation><nlm:aff id="A41">Department of Psychiatry and Psychotherapy, Charité-Universitaetsmedizin Berlin, Campus Mitte, Berlin, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A89">Department of Psychiatry, Division of Medical Psychology, Bonn, Germany.</nlm:aff></affiliation></author><author><name sortKey="Weiner, Michael W" sort="Weiner, Michael W" uniqKey="Weiner M" first="Michael W" last="Weiner">Michael W. Weiner</name><affiliation><nlm:aff id="A99">Departments of Radiology, University of California, San Francisco, California, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A100">Department of Medicine, University of California, San Francisco, California, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A101">Department of Psychiatry, University of California, San Francisco, California, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A102">Veterans Affairs Medical Center, San Francisco, California, USA.</nlm:aff></affiliation></author><author><name sortKey="Bis, Joshua C" sort="Bis, Joshua C" uniqKey="Bis J" first="Joshua C" last="Bis">Joshua C. Bis</name><affiliation><nlm:aff id="A103">Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA.</nlm:aff></affiliation></author><author><name sortKey="Ikram, M Arfan" sort="Ikram, M Arfan" uniqKey="Ikram M" first="M Arfan" last="Ikram">M Arfan Ikram</name><affiliation><nlm:aff id="A104">Department of Epidemiology, Erasmus Medical Center University Medical Center, Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A105">Department of Radiology, Erasmus Medical Center University Medical Center, Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A106">Netherlands Consortium for Healthy Aging, Leiden, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Smith, Albert V" sort="Smith, Albert V" uniqKey="Smith A" first="Albert V" last="Smith">Albert V. Smith</name><affiliation><nlm:aff id="A107">Icelandic Heart Association, Kopavogur, Iceland.</nlm:aff></affiliation><affiliation><nlm:aff id="A108">Faculty of Medicine, University of Iceland, Reykjavik, Iceland.</nlm:aff></affiliation></author><author><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name><affiliation><nlm:aff id="A107">Icelandic Heart Association, Kopavogur, Iceland.</nlm:aff></affiliation><affiliation><nlm:aff id="A108">Faculty of Medicine, University of Iceland, Reykjavik, Iceland.</nlm:aff></affiliation></author><author><name sortKey="Tzourio, Christophe" sort="Tzourio, Christophe" uniqKey="Tzourio C" first="Christophe" last="Tzourio">Christophe Tzourio</name><affiliation><nlm:aff id="A109">University of Bordeaux, U708, Bordeaux, France.</nlm:aff></affiliation><affiliation><nlm:aff id="A110">Institut National de la Santé et la Recherche Médicale (INSERM), Neuroepidemiology, U708, Bordeaux, France.</nlm:aff></affiliation></author><author><name sortKey="Vernooij, Meike W" sort="Vernooij, Meike W" uniqKey="Vernooij M" first="Meike W" last="Vernooij">Meike W. Vernooij</name><affiliation><nlm:aff id="A104">Department of Epidemiology, Erasmus Medical Center University Medical Center, Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A105">Department of Radiology, Erasmus Medical Center University Medical Center, Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A106">Netherlands Consortium for Healthy Aging, Leiden, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Launer, Lenore J" sort="Launer, Lenore J" uniqKey="Launer L" first="Lenore J" last="Launer">Lenore J. Launer</name><affiliation><nlm:aff id="A111">Laboratory of Epidemiology, Demography, and Biometry, NIH, Bethesda, Maryland, USA.</nlm:aff></affiliation></author><author><name sortKey="Decarli, Charles" sort="Decarli, Charles" uniqKey="Decarli C" first="Charles" last="Decarli">Charles Decarli</name><affiliation><nlm:aff id="A112">Department of Neurology, University of California, Davis, Sacramento, California, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A113">Center of Neuroscience, University of California, Davis, Sacramento, California, USA.</nlm:aff></affiliation></author><author><name sortKey="Seshadri, Sudha" sort="Seshadri, Sudha" uniqKey="Seshadri S" first="Sudha" last="Seshadri">Sudha Seshadri</name><affiliation><nlm:aff id="A114">Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A115">National Heart, Lung, and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts, USA.</nlm:aff></affiliation></author><author><name sortKey="Andreassen, Ole A" sort="Andreassen, Ole A" uniqKey="Andreassen O" first="Ole A" last="Andreassen">Ole A. Andreassen</name><affiliation><nlm:aff id="A16">Institute of Clinical Medicine, University of Oslo, Oslo, Norway.</nlm:aff></affiliation><affiliation><nlm:aff id="A79">Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.</nlm:aff></affiliation></author><author><name sortKey="Apostolova, Liana G" sort="Apostolova, Liana G" uniqKey="Apostolova L" first="Liana G" last="Apostolova">Liana G. Apostolova</name><affiliation><nlm:aff id="A1">Laboratory of Neuro Imaging, David Geffen School of Medicine, University of California, Los Angeles, California, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A32">Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, California, USA.</nlm:aff></affiliation></author><author><name sortKey="Bastin, Mark E" sort="Bastin, Mark E" uniqKey="Bastin M" first="Mark E" last="Bastin">Mark E. Bastin</name><affiliation><nlm:aff id="A30">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A42">Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) Collaboration, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A43">Brain Research Imaging Centre, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A116">Division of Health Sciences (Medical Physics), The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Blangero, John" sort="Blangero, John" uniqKey="Blangero J" first="John" last="Blangero">John Blangero</name><affiliation><nlm:aff id="A64">Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA.</nlm:aff></affiliation></author><author><name sortKey="Brunner, Han G" sort="Brunner, Han G" uniqKey="Brunner H" first="Han G" last="Brunner">Han G. Brunner</name><affiliation><nlm:aff id="A5">Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Buckner, Randy L" sort="Buckner, Randy L" uniqKey="Buckner R" first="Randy L" last="Buckner">Randy L. Buckner</name><affiliation><nlm:aff id="A26">Department of Psychology, Center for Brain Science, Harvard University, Cambridge, Massachusetts, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A27">Howard Hughes Medical Institute, Cambridge, Massachusetts, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A37">Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A68">Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff></affiliation></author><author><name sortKey="Cichon, Sven" sort="Cichon, Sven" uniqKey="Cichon S" first="Sven" last="Cichon">Sven Cichon</name><affiliation><nlm:aff id="A75">Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A76">Institute of Human Genetics, University of Bonn, Bonn, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A117">Institute for Neuroscience and Medicine (INM-1), Research Center Juelich, Juelich, Germany.</nlm:aff></affiliation></author><author><name sortKey="Coppola, Giovanni" sort="Coppola, Giovanni" uniqKey="Coppola G" first="Giovanni" last="Coppola">Giovanni Coppola</name><affiliation><nlm:aff id="A32">Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, California, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A118">Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, California, USA.</nlm:aff></affiliation></author><author><name sortKey="De Zubicaray, Greig I" sort="De Zubicaray, Greig I" uniqKey="De Zubicaray G" first="Greig I" last="De Zubicaray">Greig I. De Zubicaray</name><affiliation><nlm:aff id="A86">School of Psychology, University of Queensland, Brisbane, Queensland, Australia.</nlm:aff></affiliation></author><author><name sortKey="Deary, Ian J" sort="Deary, Ian J" uniqKey="Deary I" first="Ian J" last="Deary">Ian J. Deary</name><affiliation><nlm:aff id="A30">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A31">Department of Psychology, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Donohoe, Gary" sort="Donohoe, Gary" uniqKey="Donohoe G" first="Gary" last="Donohoe">Gary Donohoe</name><affiliation><nlm:aff id="A46">Neuropsychiatric Genetics Research Group, Department of Psychiatry, Institute for Molecular Medicine, Trinity College, Dublin, Ireland.</nlm:aff></affiliation><affiliation><nlm:aff id="A47">Trinity College Institute of Neuroscience, Trinity College, Dublin, Ireland.</nlm:aff></affiliation></author><author><name sortKey="De Geus, Eco J C" sort="De Geus, Eco J C" uniqKey="De Geus E" first="Eco J C" last="De Geus">Eco J C. De Geus</name><affiliation><nlm:aff id="A29">Department of Biological Psychology, Neuroscience Campus Amsterdam, VU University, Amsterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Espeseth, Thomas" sort="Espeseth, Thomas" uniqKey="Espeseth T" first="Thomas" last="Espeseth">Thomas Espeseth</name><affiliation><nlm:aff id="A84">Center for the Study of Human Cognition, Department of Psychology, University of Oslo, Oslo, Norway.</nlm:aff></affiliation><affiliation><nlm:aff id="A85">Centre for Advanced Study, Oslo, Norway.</nlm:aff></affiliation><affiliation><nlm:aff id="A119">Department of Biological and Medical Psychology, Faculty of Psychology, University of Bergen, Bergen, Norway.</nlm:aff></affiliation></author><author><name sortKey="Fernandez, Guillen" sort="Fernandez, Guillen" uniqKey="Fernandez G" first="Guillén" last="Fernández">Guillén Fernández</name><affiliation><nlm:aff id="A7">Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A52">Donders Centre for Cognitive Neuroimaging, Radboud University Nijmegen, Nijmegen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A71">Department of Cognitive Neuroscience, Radboud University Nijmegen Medical Centre, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Glahn, David C" sort="Glahn, David C" uniqKey="Glahn D" first="David C" last="Glahn">David C. Glahn</name><affiliation><nlm:aff id="A8">Olin Neuropsychiatry Research Center, Institute of Living, Hartford Hospital, Hartford, Connecticut, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A9">Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA.</nlm:aff></affiliation></author><author><name sortKey="Grabe, Hans J" sort="Grabe, Hans J" uniqKey="Grabe H" first="Hans J" last="Grabe">Hans J. Grabe</name><affiliation><nlm:aff id="A13">Department of Psychiatry and Psychotherapy, University of Greifswald, Greifswald, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A120">German Center for Neurodegenerative Diseases (DZNE), Rostock/Greifswald, Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Hardy, John" sort="Hardy, John" uniqKey="Hardy J" first="John" last="Hardy">John Hardy</name><affiliation><nlm:aff id="A54">Department of Molecular Neuroscience, University College London, London, UK.</nlm:aff></affiliation></author><author><name sortKey="Hulshoff Pol, Hilleke E" sort="Hulshoff Pol, Hilleke E" uniqKey="Hulshoff Pol H" first="Hilleke E" last="Hulshoff Pol">Hilleke E. Hulshoff Pol</name><affiliation><nlm:aff id="A15">Department of Psychiatry, Rudolf Magnus Institute, University Medical Center Utrecht, Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Jenkinson, Mark" sort="Jenkinson, Mark" uniqKey="Jenkinson M" first="Mark" last="Jenkinson">Mark Jenkinson</name><affiliation><nlm:aff id="A121">Functional Magnetic Resonance Imaging of the Brain (FMRIB) Centre, Oxford University, Oxford, UK.</nlm:aff></affiliation></author><author><name sortKey="Kahn, Rene S" sort="Kahn, Rene S" uniqKey="Kahn R" first="René S" last="Kahn">René S. Kahn</name><affiliation><nlm:aff id="A15">Department of Psychiatry, Rudolf Magnus Institute, University Medical Center Utrecht, Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Mcdonald, Colm" sort="Mcdonald, Colm" uniqKey="Mcdonald C" first="Colm" last="Mcdonald">Colm Mcdonald</name><affiliation><nlm:aff id="A20">Clinical Neuroimaging Laboratory, Department of Psychiatry, National University of Ireland Galway, Galway, Ireland.</nlm:aff></affiliation></author><author><name sortKey="Mcintosh, Andrew M" sort="Mcintosh, Andrew M" uniqKey="Mcintosh A" first="Andrew M" last="Mcintosh">Andrew M. Mcintosh</name><affiliation><nlm:aff id="A48">Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Mcmahon, Francis J" sort="Mcmahon, Francis J" uniqKey="Mcmahon F" first="Francis J" last="Mcmahon">Francis J. Mcmahon</name><affiliation><nlm:aff id="A35">Mood and Anxiety Disorders Section, Human Genetics Branch, Intramural Research Program, National Institute of Mental Health (NIMH), US National Institutes of Health (NIH), US Department of Health and Human Services, Bethesda, Maryland, USA.</nlm:aff></affiliation></author><author><name sortKey="Mcmahon, Katie L" sort="Mcmahon, Katie L" uniqKey="Mcmahon K" first="Katie L" last="Mcmahon">Katie L. Mcmahon</name><affiliation><nlm:aff id="A122">Centre for Advanced Imaging, University of Queensland, Brisbane, Queensland, Australia.</nlm:aff></affiliation></author><author><name sortKey="Meyer Lindenberg, Andreas" sort="Meyer Lindenberg, Andreas" uniqKey="Meyer Lindenberg A" first="Andreas" last="Meyer-Lindenberg">Andreas Meyer-Lindenberg</name><affiliation><nlm:aff id="A25">Central Institute of Mental Health, University of Heidelberg–Medical Faculty Mannheim, Mannheim, Germany.</nlm:aff></affiliation></author><author><name sortKey="Morris, Derek W" sort="Morris, Derek W" uniqKey="Morris D" first="Derek W" last="Morris">Derek W. Morris</name><affiliation><nlm:aff id="A46">Neuropsychiatric Genetics Research Group, Department of Psychiatry, Institute for Molecular Medicine, Trinity College, Dublin, Ireland.</nlm:aff></affiliation><affiliation><nlm:aff id="A47">Trinity College Institute of Neuroscience, Trinity College, Dublin, Ireland.</nlm:aff></affiliation></author><author><name sortKey="Muller Myhsok, Bertram" sort="Muller Myhsok, Bertram" uniqKey="Muller Myhsok B" first="Bertram" last="Müller-Myhsok">Bertram Müller-Myhsok</name><affiliation><nlm:aff id="A49">Max Planck Institute of Psychiatry, Munich, Germany.</nlm:aff></affiliation></author><author><name sortKey="Nichols, Thomas E" sort="Nichols, Thomas E" uniqKey="Nichols T" first="Thomas E" last="Nichols">Thomas E. Nichols</name><affiliation><nlm:aff id="A121">Functional Magnetic Resonance Imaging of the Brain (FMRIB) Centre, Oxford University, Oxford, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A123">Department of Statistics, University of Warwick, Coventry, UK.</nlm:aff></affiliation></author><author><name sortKey="Ophoff, Roel A" sort="Ophoff, Roel A" uniqKey="Ophoff R" first="Roel A" last="Ophoff">Roel A. Ophoff</name><affiliation><nlm:aff id="A15">Department of Psychiatry, Rudolf Magnus Institute, University Medical Center Utrecht, Utrecht, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A65">Center for Neurobehavioral Genetics, University of California, Los Angeles, USA.</nlm:aff></affiliation></author><author><name sortKey="Paus, Tomas" sort="Paus, Tomas" uniqKey="Paus T" first="Tomas" last="Paus">Tomas Paus</name><affiliation><nlm:aff id="A21">Rotman Research Institute, University of Toronto, Toronto, Ontario, Canada.</nlm:aff></affiliation></author><author><name sortKey="Pausova, Zdenka" sort="Pausova, Zdenka" uniqKey="Pausova Z" first="Zdenka" last="Pausova">Zdenka Pausova</name><affiliation><nlm:aff id="A17">The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.</nlm:aff></affiliation></author><author><name sortKey="Penninx, Brenda W" sort="Penninx, Brenda W" uniqKey="Penninx B" first="Brenda W" last="Penninx">Brenda W. Penninx</name><affiliation><nlm:aff id="A59">Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A60">Leiden Institute for Brain and Cognition, Leiden University, Leiden, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A62">Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A124">Department of Psychiatry, University Medical Center Groningen, Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Potkin, Steven G" sort="Potkin, Steven G" uniqKey="Potkin S" first="Steven G" last="Potkin">Steven G. Potkin</name><affiliation><nlm:aff id="A51">Department of Psychiatry and Human Behavior, University of California, Irvine, California, USA.</nlm:aff></affiliation></author><author><name sortKey="S Mann, Philipp G" sort="S Mann, Philipp G" uniqKey="S Mann P" first="Philipp G" last="S Mann">Philipp G. S Mann</name><affiliation><nlm:aff id="A49">Max Planck Institute of Psychiatry, Munich, Germany.</nlm:aff></affiliation></author><author><name sortKey="Saykin, Andrew J" sort="Saykin, Andrew J" uniqKey="Saykin A" first="Andrew J" last="Saykin">Andrew J. Saykin</name><affiliation><nlm:aff id="A33">Department of Radiology and Imaging Sciences, Center for Neuroimaging, Indiana University School of Medicine, Indianapolis, Indiana, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A34">Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, Indiana, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A95">Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA.</nlm:aff></affiliation></author><author><name sortKey="Schumann, Gunter" sort="Schumann, Gunter" uniqKey="Schumann G" first="Gunter" last="Schumann">Gunter Schumann</name><affiliation><nlm:aff id="A39">Medical Research Council (MRC)–Social, Genetic and Developmental Psychiatry (SGDP) Centre, Institute of Psychiatry, King’s College London, London, UK.</nlm:aff></affiliation></author><author><name sortKey="Smoller, Jordan W" sort="Smoller, Jordan W" uniqKey="Smoller J" first="Jordan W" last="Smoller">Jordan W. Smoller</name><affiliation><nlm:aff id="A36">Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A37">Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff></affiliation></author><author><name sortKey="Wardlaw, Joanna M" sort="Wardlaw, Joanna M" uniqKey="Wardlaw J" first="Joanna M" last="Wardlaw">Joanna M. Wardlaw</name><affiliation><nlm:aff id="A30">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A42">Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) Collaboration, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A43">Brain Research Imaging Centre, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Weale, Michael E" sort="Weale, Michael E" uniqKey="Weale M" first="Michael E" last="Weale">Michael E. Weale</name><affiliation><nlm:aff id="A50">Department of Medical & Molecular Genetics, King’s College London, London, UK.</nlm:aff></affiliation></author><author><name sortKey="Martin, Nicholas G" sort="Martin, Nicholas G" uniqKey="Martin N" first="Nicholas G" last="Martin">Nicholas G. Martin</name><affiliation><nlm:aff id="A2">Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland, Australia.</nlm:aff></affiliation></author><author><name sortKey="Franke, Barbara" sort="Franke, Barbara" uniqKey="Franke B" first="Barbara" last="Franke">Barbara Franke</name><affiliation><nlm:aff id="A5">Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A6">Department of Psychiatry, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A7">Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Wright, Margaret J" sort="Wright, Margaret J" uniqKey="Wright M" first="Margaret J" last="Wright">Margaret J. Wright</name><affiliation><nlm:aff id="A2">Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland, Australia.</nlm:aff></affiliation></author><author><name sortKey="Thompson, Paul M" sort="Thompson, Paul M" uniqKey="Thompson P" first="Paul M" last="Thompson">Paul M. Thompson</name><affiliation><nlm:aff id="A1">Laboratory of Neuro Imaging, David Geffen School of Medicine, University of California, Los Angeles, California, USA.</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">22504417</idno><idno type="pmc">3635491</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635491</idno><idno type="RBID">PMC:3635491</idno><idno type="doi">10.1038/ng.2250</idno><date when="2012">2012</date><idno type="wicri:Area/Pmc/Corpus">002131</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002131</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Identification of common variants associated with human hippocampal and intracranial volumes</title><author><name sortKey="Stein, Jason L" sort="Stein, Jason L" uniqKey="Stein J" first="Jason L" last="Stein">Jason L. Stein</name><affiliation><nlm:aff id="A1">Laboratory of Neuro Imaging, David Geffen School of Medicine, University of California, Los Angeles, California, USA.</nlm:aff></affiliation></author><author><name sortKey="Medland, Sarah E" sort="Medland, Sarah E" uniqKey="Medland S" first="Sarah E" last="Medland">Sarah E. Medland</name><affiliation><nlm:aff id="A2">Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland, Australia.</nlm:aff></affiliation><affiliation><nlm:aff id="A3">Quantitative Genetics Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland, Australia.</nlm:aff></affiliation><affiliation><nlm:aff id="A4">Broad Institute of Harvard University and MIT, Cambridge, Massachusetts, USA.</nlm:aff></affiliation></author><author><name sortKey="Vasquez, Alejandro Arias" sort="Vasquez, Alejandro Arias" uniqKey="Vasquez A" first="Alejandro Arias" last="Vasquez">Alejandro Arias Vasquez</name><affiliation><nlm:aff id="A5">Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A6">Department of Psychiatry, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A7">Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Hibar, Derrek P" sort="Hibar, Derrek P" uniqKey="Hibar D" first="Derrek P" last="Hibar">Derrek P. Hibar</name><affiliation><nlm:aff id="A1">Laboratory of Neuro Imaging, David Geffen School of Medicine, University of California, Los Angeles, California, USA.</nlm:aff></affiliation></author><author><name sortKey="Senstad, Rudy E" sort="Senstad, Rudy E" uniqKey="Senstad R" first="Rudy E" last="Senstad">Rudy E. Senstad</name><affiliation><nlm:aff id="A1">Laboratory of Neuro Imaging, David Geffen School of Medicine, University of California, Los Angeles, California, USA.</nlm:aff></affiliation></author><author><name sortKey="Winkler, Anderson M" sort="Winkler, Anderson M" uniqKey="Winkler A" first="Anderson M" last="Winkler">Anderson M. Winkler</name><affiliation><nlm:aff id="A8">Olin Neuropsychiatry Research Center, Institute of Living, Hartford Hospital, Hartford, Connecticut, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A9">Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA.</nlm:aff></affiliation></author><author><name sortKey="Toro, Roberto" sort="Toro, Roberto" uniqKey="Toro R" first="Roberto" last="Toro">Roberto Toro</name><affiliation><nlm:aff id="A10">Laboratory of Human Genetics and Cognitive Functions, Institut Pasteur, Paris, France.</nlm:aff></affiliation><affiliation><nlm:aff id="A11">Centre Nationale de Recherche Scientifique (CNRS) Unité de Recherche Associée (URA) 2182 Genes, Synapses and Cognition, Institut Pasteur, Paris, France.</nlm:aff></affiliation><affiliation><nlm:aff id="A12">Department of Neuroscience, Université Paris Diderot, Sorbonne Paris Cité, Paris, France.</nlm:aff></affiliation></author><author><name sortKey="Appel, Katja" sort="Appel, Katja" uniqKey="Appel K" first="Katja" last="Appel">Katja Appel</name><affiliation><nlm:aff id="A13">Department of Psychiatry and Psychotherapy, University of Greifswald, Greifswald, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A14">Institute of Psychology, Department of Clinical Psychology and Psychotherapy, University of Heidelberg, Heidelberg, Germany.</nlm:aff></affiliation></author><author><name sortKey="Bartecek, Richard" sort="Bartecek, Richard" uniqKey="Bartecek R" first="Richard" last="Bartecek">Richard Bartecek</name><affiliation><nlm:aff id="A15">Department of Psychiatry, Rudolf Magnus Institute, University Medical Center Utrecht, Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Bergmann, Rjan" sort="Bergmann, Rjan" uniqKey="Bergmann " first=" Rjan" last="Bergmann"> Rjan Bergmann</name><affiliation><nlm:aff id="A16">Institute of Clinical Medicine, University of Oslo, Oslo, Norway.</nlm:aff></affiliation></author><author><name sortKey="Bernard, Manon" sort="Bernard, Manon" uniqKey="Bernard M" first="Manon" last="Bernard">Manon Bernard</name><affiliation><nlm:aff id="A17">The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.</nlm:aff></affiliation></author><author><name sortKey="Brown, Andrew A" sort="Brown, Andrew A" uniqKey="Brown A" first="Andrew A" last="Brown">Andrew A. Brown</name><affiliation><nlm:aff id="A16">Institute of Clinical Medicine, University of Oslo, Oslo, Norway.</nlm:aff></affiliation><affiliation><nlm:aff id="A18">Institute of Basic Medical Sciences, Department of Biostatistics, University of Oslo, Oslo, Norway.</nlm:aff></affiliation></author><author><name sortKey="Cannon, Dara M" sort="Cannon, Dara M" uniqKey="Cannon D" first="Dara M" last="Cannon">Dara M. Cannon</name><affiliation><nlm:aff id="A19">Clinical Neuroimaging Laboratory, Department of Anatomy, National University of Ireland Galway, Galway, Ireland.</nlm:aff></affiliation></author><author><name sortKey="Chakravarty, M Mallar" sort="Chakravarty, M Mallar" uniqKey="Chakravarty M" first="M Mallar" last="Chakravarty">M Mallar Chakravarty</name><affiliation><nlm:aff id="A21">Rotman Research Institute, University of Toronto, Toronto, Ontario, Canada.</nlm:aff></affiliation></author><author><name sortKey="Christoforou, Andrea" sort="Christoforou, Andrea" uniqKey="Christoforou A" first="Andrea" last="Christoforou">Andrea Christoforou</name><affiliation><nlm:aff id="A22">Dr Einar Martens Research Group for Biological Psychiatry, Department of Clinical Medicine, University of Bergen, Bergen, Norway.</nlm:aff></affiliation><affiliation><nlm:aff id="A23">Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway.</nlm:aff></affiliation></author><author><name sortKey="Domin, Martin" sort="Domin, Martin" uniqKey="Domin M" first="Martin" last="Domin">Martin Domin</name><affiliation><nlm:aff id="A24">Department of Diagnostic Radiology and Neuroradiology, University of Greifswald, Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Grimm, Oliver" sort="Grimm, Oliver" uniqKey="Grimm O" first="Oliver" last="Grimm">Oliver Grimm</name><affiliation><nlm:aff id="A25">Central Institute of Mental Health, University of Heidelberg–Medical Faculty Mannheim, Mannheim, Germany.</nlm:aff></affiliation></author><author><name sortKey="Hollinshead, Marisa" sort="Hollinshead, Marisa" uniqKey="Hollinshead M" first="Marisa" last="Hollinshead">Marisa Hollinshead</name><affiliation><nlm:aff id="A26">Department of Psychology, Center for Brain Science, Harvard University, Cambridge, Massachusetts, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A27">Howard Hughes Medical Institute, Cambridge, Massachusetts, USA.</nlm:aff></affiliation></author><author><name sortKey="Holmes, Avram J" sort="Holmes, Avram J" uniqKey="Holmes A" first="Avram J" last="Holmes">Avram J. Holmes</name><affiliation><nlm:aff id="A26">Department of Psychology, Center for Brain Science, Harvard University, Cambridge, Massachusetts, USA.</nlm:aff></affiliation></author><author><name sortKey="Homuth, Georg" sort="Homuth, Georg" uniqKey="Homuth G" first="Georg" last="Homuth">Georg Homuth</name><affiliation><nlm:aff id="A28">Interfaculty Institute for Genetics and Functional Genomics, University of Greifswald, Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Hottenga, Jouke Jan" sort="Hottenga, Jouke Jan" uniqKey="Hottenga J" first="Jouke-Jan" last="Hottenga">Jouke-Jan Hottenga</name><affiliation><nlm:aff id="A29">Department of Biological Psychology, Neuroscience Campus Amsterdam, VU University, Amsterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Langan, Camilla" sort="Langan, Camilla" uniqKey="Langan C" first="Camilla" last="Langan">Camilla Langan</name><affiliation><nlm:aff id="A20">Clinical Neuroimaging Laboratory, Department of Psychiatry, National University of Ireland Galway, Galway, Ireland.</nlm:aff></affiliation></author><author><name sortKey="Lopez, Lorna M" sort="Lopez, Lorna M" uniqKey="Lopez L" first="Lorna M" last="Lopez">Lorna M. Lopez</name><affiliation><nlm:aff id="A30">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A31">Department of Psychology, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Hansell, Narelle K" sort="Hansell, Narelle K" uniqKey="Hansell N" first="Narelle K" last="Hansell">Narelle K. Hansell</name><affiliation><nlm:aff id="A2">Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland, Australia.</nlm:aff></affiliation></author><author><name sortKey="Hwang, Kristy S" sort="Hwang, Kristy S" uniqKey="Hwang K" first="Kristy S" last="Hwang">Kristy S. Hwang</name><affiliation><nlm:aff id="A1">Laboratory of Neuro Imaging, David Geffen School of Medicine, University of California, Los Angeles, California, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A32">Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, California, USA.</nlm:aff></affiliation></author><author><name sortKey="Kim, Sungeun" sort="Kim, Sungeun" uniqKey="Kim S" first="Sungeun" last="Kim">Sungeun Kim</name><affiliation><nlm:aff id="A33">Department of Radiology and Imaging Sciences, Center for Neuroimaging, Indiana University School of Medicine, Indianapolis, Indiana, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A34">Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, Indiana, USA.</nlm:aff></affiliation></author><author><name sortKey="Laje, Gonzalo" sort="Laje, Gonzalo" uniqKey="Laje G" first="Gonzalo" last="Laje">Gonzalo Laje</name><affiliation><nlm:aff id="A35">Mood and Anxiety Disorders Section, Human Genetics Branch, Intramural Research Program, National Institute of Mental Health (NIMH), US National Institutes of Health (NIH), US Department of Health and Human Services, Bethesda, Maryland, USA.</nlm:aff></affiliation></author><author><name sortKey="Lee, Phil H" sort="Lee, Phil H" uniqKey="Lee P" first="Phil H" last="Lee">Phil H. Lee</name><affiliation><nlm:aff id="A36">Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A37">Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff></affiliation></author><author><name sortKey="Liu, Xinmin" sort="Liu, Xinmin" uniqKey="Liu X" first="Xinmin" last="Liu">Xinmin Liu</name><affiliation><nlm:aff id="A35">Mood and Anxiety Disorders Section, Human Genetics Branch, Intramural Research Program, National Institute of Mental Health (NIMH), US National Institutes of Health (NIH), US Department of Health and Human Services, Bethesda, Maryland, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A38">Taub Institute for Research on Alzheimer Disease and the Aging Brain, Columbia University Medical Center, New York, New York, USA.</nlm:aff></affiliation></author><author><name sortKey="Loth, Eva" sort="Loth, Eva" uniqKey="Loth E" first="Eva" last="Loth">Eva Loth</name><affiliation><nlm:aff id="A39">Medical Research Council (MRC)–Social, Genetic and Developmental Psychiatry (SGDP) Centre, Institute of Psychiatry, King’s College London, London, UK.</nlm:aff></affiliation></author><author><name sortKey="Lourdusamy, Anbarasu" sort="Lourdusamy, Anbarasu" uniqKey="Lourdusamy A" first="Anbarasu" last="Lourdusamy">Anbarasu Lourdusamy</name><affiliation><nlm:aff id="A39">Medical Research Council (MRC)–Social, Genetic and Developmental Psychiatry (SGDP) Centre, Institute of Psychiatry, King’s College London, London, UK.</nlm:aff></affiliation></author><author><name sortKey="Mattingsdal, Morten" sort="Mattingsdal, Morten" uniqKey="Mattingsdal M" first="Morten" last="Mattingsdal">Morten Mattingsdal</name><affiliation><nlm:aff id="A16">Institute of Clinical Medicine, University of Oslo, Oslo, Norway.</nlm:aff></affiliation><affiliation><nlm:aff id="A40">Research Unit, Sørlandet Hospital, Kristiansand, Norway.</nlm:aff></affiliation></author><author><name sortKey="Mohnke, Sebastian" sort="Mohnke, Sebastian" uniqKey="Mohnke S" first="Sebastian" last="Mohnke">Sebastian Mohnke</name><affiliation><nlm:aff id="A41">Department of Psychiatry and Psychotherapy, Charité-Universitaetsmedizin Berlin, Campus Mitte, Berlin, Germany.</nlm:aff></affiliation></author><author><name sortKey="Maniega, Susana Mu Oz" sort="Maniega, Susana Mu Oz" uniqKey="Maniega S" first="Susana Mu Oz" last="Maniega">Susana Mu Oz Maniega</name><affiliation><nlm:aff id="A30">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A42">Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) Collaboration, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A43">Brain Research Imaging Centre, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Nho, Kwangsik" sort="Nho, Kwangsik" uniqKey="Nho K" first="Kwangsik" last="Nho">Kwangsik Nho</name><affiliation><nlm:aff id="A33">Department of Radiology and Imaging Sciences, Center for Neuroimaging, Indiana University School of Medicine, Indianapolis, Indiana, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A44">Division of Medical Informatics, Regenstrief Institute, Indianapolis, Indiana, USA.</nlm:aff></affiliation></author><author><name sortKey="Nugent, Allison C" sort="Nugent, Allison C" uniqKey="Nugent A" first="Allison C" last="Nugent">Allison C. Nugent</name><affiliation><nlm:aff id="A45">Section on Neuroimaging in Mood and Anxiety Disorders, Intramural Research Program, NIMH, NIH, US Department of Health and Human Services, Bethesda, Maryland, USA.</nlm:aff></affiliation></author><author><name sortKey="O Rien, Carol" sort="O Rien, Carol" uniqKey="O Rien C" first="Carol" last="O Rien">Carol O Rien</name><affiliation><nlm:aff id="A46">Neuropsychiatric Genetics Research Group, Department of Psychiatry, Institute for Molecular Medicine, Trinity College, Dublin, Ireland.</nlm:aff></affiliation><affiliation><nlm:aff id="A47">Trinity College Institute of Neuroscience, Trinity College, Dublin, Ireland.</nlm:aff></affiliation></author><author><name sortKey="Papmeyer, Martina" sort="Papmeyer, Martina" uniqKey="Papmeyer M" first="Martina" last="Papmeyer">Martina Papmeyer</name><affiliation><nlm:aff id="A48">Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Putz, Benno" sort="Putz, Benno" uniqKey="Putz B" first="Benno" last="Pütz">Benno Pütz</name><affiliation><nlm:aff id="A49">Max Planck Institute of Psychiatry, Munich, Germany.</nlm:aff></affiliation></author><author><name sortKey="Ramasamy, Adaikalavan" sort="Ramasamy, Adaikalavan" uniqKey="Ramasamy A" first="Adaikalavan" last="Ramasamy">Adaikalavan Ramasamy</name><affiliation><nlm:aff id="A50">Department of Medical & Molecular Genetics, King’s College London, London, UK.</nlm:aff></affiliation></author><author><name sortKey="Rasmussen, Jerod" sort="Rasmussen, Jerod" uniqKey="Rasmussen J" first="Jerod" last="Rasmussen">Jerod Rasmussen</name><affiliation><nlm:aff id="A51">Department of Psychiatry and Human Behavior, University of California, Irvine, California, USA.</nlm:aff></affiliation></author><author><name sortKey="Rijpkema, Mark" sort="Rijpkema, Mark" uniqKey="Rijpkema M" first="Mark" last="Rijpkema">Mark Rijpkema</name><affiliation><nlm:aff id="A7">Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A52">Donders Centre for Cognitive Neuroimaging, Radboud University Nijmegen, Nijmegen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Risacher, Shannon L" sort="Risacher, Shannon L" uniqKey="Risacher S" first="Shannon L" last="Risacher">Shannon L. Risacher</name><affiliation><nlm:aff id="A33">Department of Radiology and Imaging Sciences, Center for Neuroimaging, Indiana University School of Medicine, Indianapolis, Indiana, USA.</nlm:aff></affiliation></author><author><name sortKey="Roddey, J Cooper" sort="Roddey, J Cooper" uniqKey="Roddey J" first="J Cooper" last="Roddey">J Cooper Roddey</name><affiliation><nlm:aff id="A53">Department of Neurosciences, University of California, San Diego, La Jolla, California, USA.</nlm:aff></affiliation></author><author><name sortKey="Rose, Emma J" sort="Rose, Emma J" uniqKey="Rose E" first="Emma J" last="Rose">Emma J. Rose</name><affiliation><nlm:aff id="A46">Neuropsychiatric Genetics Research Group, Department of Psychiatry, Institute for Molecular Medicine, Trinity College, Dublin, Ireland.</nlm:aff></affiliation><affiliation><nlm:aff id="A47">Trinity College Institute of Neuroscience, Trinity College, Dublin, Ireland.</nlm:aff></affiliation></author><author><name sortKey="Ryten, Mina" sort="Ryten, Mina" uniqKey="Ryten M" first="Mina" last="Ryten">Mina Ryten</name><affiliation><nlm:aff id="A54">Department of Molecular Neuroscience, University College London, London, UK.</nlm:aff></affiliation></author><author><name sortKey="Shen, Li" sort="Shen, Li" uniqKey="Shen L" first="Li" last="Shen">Li Shen</name><affiliation><nlm:aff id="A33">Department of Radiology and Imaging Sciences, Center for Neuroimaging, Indiana University School of Medicine, Indianapolis, Indiana, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A34">Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, Indiana, USA.</nlm:aff></affiliation></author><author><name sortKey="Sprooten, Emma" sort="Sprooten, Emma" uniqKey="Sprooten E" first="Emma" last="Sprooten">Emma Sprooten</name><affiliation><nlm:aff id="A48">Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Strengman, Eric" sort="Strengman, Eric" uniqKey="Strengman E" first="Eric" last="Strengman">Eric Strengman</name><affiliation><nlm:aff id="A55">Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A56">Rudolf Magnus Institute, University Medical Center Utrecht, Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Teumer, Alexander" sort="Teumer, Alexander" uniqKey="Teumer A" first="Alexander" last="Teumer">Alexander Teumer</name><affiliation><nlm:aff id="A28">Interfaculty Institute for Genetics and Functional Genomics, University of Greifswald, Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Trabzuni, Daniah" sort="Trabzuni, Daniah" uniqKey="Trabzuni D" first="Daniah" last="Trabzuni">Daniah Trabzuni</name><affiliation><nlm:aff id="A54">Department of Molecular Neuroscience, University College London, London, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A57">Department of Genetics, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.</nlm:aff></affiliation></author><author><name sortKey="Turner, Jessica" sort="Turner, Jessica" uniqKey="Turner J" first="Jessica" last="Turner">Jessica Turner</name><affiliation><nlm:aff id="A58">Mind Research Network, Albuquerque, New Mexico, USA.</nlm:aff></affiliation></author><author><name sortKey="Van Eijk, Kristel" sort="Van Eijk, Kristel" uniqKey="Van Eijk K" first="Kristel" last="Van Eijk">Kristel Van Eijk</name><affiliation><nlm:aff id="A55">Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A56">Rudolf Magnus Institute, University Medical Center Utrecht, Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Van Erp, Theo G M" sort="Van Erp, Theo G M" uniqKey="Van Erp T" first="Theo G M" last="Van Erp">Theo G M. Van Erp</name><affiliation><nlm:aff id="A51">Department of Psychiatry and Human Behavior, University of California, Irvine, California, USA.</nlm:aff></affiliation></author><author><name sortKey="Van Tol, Marie Jose" sort="Van Tol, Marie Jose" uniqKey="Van Tol M" first="Marie-Jose" last="Van Tol">Marie-Jose Van Tol</name><affiliation><nlm:aff id="A59">Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A60">Leiden Institute for Brain and Cognition, Leiden University, Leiden, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A61">Behavioural and Cognitive Neuroscience Neuroimaging Center, University Medical Center Groningen, Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Wittfeld, Katharina" sort="Wittfeld, Katharina" uniqKey="Wittfeld K" first="Katharina" last="Wittfeld">Katharina Wittfeld</name><affiliation><nlm:aff id="A13">Department of Psychiatry and Psychotherapy, University of Greifswald, Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Wolf, Christiane" sort="Wolf, Christiane" uniqKey="Wolf C" first="Christiane" last="Wolf">Christiane Wolf</name><affiliation><nlm:aff id="A49">Max Planck Institute of Psychiatry, Munich, Germany.</nlm:aff></affiliation></author><author><name sortKey="Woudstra, Saskia" sort="Woudstra, Saskia" uniqKey="Woudstra S" first="Saskia" last="Woudstra">Saskia Woudstra</name><affiliation><nlm:aff id="A62">Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Aleman, Andre" sort="Aleman, Andre" uniqKey="Aleman A" first="Andre" last="Aleman">Andre Aleman</name><affiliation><nlm:aff id="A61">Behavioural and Cognitive Neuroscience Neuroimaging Center, University Medical Center Groningen, Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Alhusaini, Saud" sort="Alhusaini, Saud" uniqKey="Alhusaini S" first="Saud" last="Alhusaini">Saud Alhusaini</name><affiliation><nlm:aff id="A63">Department of Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.</nlm:aff></affiliation></author><author><name sortKey="Almasy, Laura" sort="Almasy, Laura" uniqKey="Almasy L" first="Laura" last="Almasy">Laura Almasy</name><affiliation><nlm:aff id="A64">Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA.</nlm:aff></affiliation></author><author><name sortKey="Binder, Elisabeth B" sort="Binder, Elisabeth B" uniqKey="Binder E" first="Elisabeth B" last="Binder">Elisabeth B. Binder</name><affiliation><nlm:aff id="A49">Max Planck Institute of Psychiatry, Munich, Germany.</nlm:aff></affiliation></author><author><name sortKey="Brohawn, David G" sort="Brohawn, David G" uniqKey="Brohawn D" first="David G" last="Brohawn">David G. Brohawn</name><affiliation><nlm:aff id="A36">Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff></affiliation></author><author><name sortKey="Cantor, Rita M" sort="Cantor, Rita M" uniqKey="Cantor R" first="Rita M" last="Cantor">Rita M. Cantor</name><affiliation><nlm:aff id="A65">Center for Neurobehavioral Genetics, University of California, Los Angeles, USA.</nlm:aff></affiliation></author><author><name sortKey="Carless, Melanie A" sort="Carless, Melanie A" uniqKey="Carless M" first="Melanie A" last="Carless">Melanie A. Carless</name><affiliation><nlm:aff id="A64">Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA.</nlm:aff></affiliation></author><author><name sortKey="Corvin, Aiden" sort="Corvin, Aiden" uniqKey="Corvin A" first="Aiden" last="Corvin">Aiden Corvin</name><affiliation><nlm:aff id="A46">Neuropsychiatric Genetics Research Group, Department of Psychiatry, Institute for Molecular Medicine, Trinity College, Dublin, Ireland.</nlm:aff></affiliation><affiliation><nlm:aff id="A47">Trinity College Institute of Neuroscience, Trinity College, Dublin, Ireland.</nlm:aff></affiliation></author><author><name sortKey="Czisch, Michael" sort="Czisch, Michael" uniqKey="Czisch M" first="Michael" last="Czisch">Michael Czisch</name><affiliation><nlm:aff id="A49">Max Planck Institute of Psychiatry, Munich, Germany.</nlm:aff></affiliation></author><author><name sortKey="Curran, Joanne E" sort="Curran, Joanne E" uniqKey="Curran J" first="Joanne E" last="Curran">Joanne E. Curran</name><affiliation><nlm:aff id="A64">Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA.</nlm:aff></affiliation></author><author><name sortKey="Davies, Gail" sort="Davies, Gail" uniqKey="Davies G" first="Gail" last="Davies">Gail Davies</name><affiliation><nlm:aff id="A31">Department of Psychology, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="De Almeida, Marcio A A" sort="De Almeida, Marcio A A" uniqKey="De Almeida M" first="Marcio A A" last="De Almeida">Marcio A A. De Almeida</name><affiliation><nlm:aff id="A64">Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA.</nlm:aff></affiliation></author><author><name sortKey="Delanty, Norman" sort="Delanty, Norman" uniqKey="Delanty N" first="Norman" last="Delanty">Norman Delanty</name><affiliation><nlm:aff id="A63">Department of Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.</nlm:aff></affiliation><affiliation><nlm:aff id="A66">Division of Neurology, Beaumont Hospital, Dublin, Ireland.</nlm:aff></affiliation></author><author><name sortKey="Depondt, Chantal" sort="Depondt, Chantal" uniqKey="Depondt C" first="Chantal" last="Depondt">Chantal Depondt</name><affiliation><nlm:aff id="A67">Department of Neurology, Hopital Erasme, Universite Libre de Bruxelles, Brussels, Belgium.</nlm:aff></affiliation></author><author><name sortKey="Duggirala, Ravi" sort="Duggirala, Ravi" uniqKey="Duggirala R" first="Ravi" last="Duggirala">Ravi Duggirala</name><affiliation><nlm:aff id="A64">Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA.</nlm:aff></affiliation></author><author><name sortKey="Dyer, Thomas D" sort="Dyer, Thomas D" uniqKey="Dyer T" first="Thomas D" last="Dyer">Thomas D. Dyer</name><affiliation><nlm:aff id="A64">Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA.</nlm:aff></affiliation></author><author><name sortKey="Erk, Susanne" sort="Erk, Susanne" uniqKey="Erk S" first="Susanne" last="Erk">Susanne Erk</name><affiliation><nlm:aff id="A41">Department of Psychiatry and Psychotherapy, Charité-Universitaetsmedizin Berlin, Campus Mitte, Berlin, Germany.</nlm:aff></affiliation></author><author><name sortKey="Fagerness, Jesen" sort="Fagerness, Jesen" uniqKey="Fagerness J" first="Jesen" last="Fagerness">Jesen Fagerness</name><affiliation><nlm:aff id="A36">Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff></affiliation></author><author><name sortKey="Fox, Peter T" sort="Fox, Peter T" uniqKey="Fox P" first="Peter T" last="Fox">Peter T. Fox</name><affiliation><nlm:aff id="A69">Research Imaging Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.</nlm:aff></affiliation></author><author><name sortKey="Freimer, Nelson B" sort="Freimer, Nelson B" uniqKey="Freimer N" first="Nelson B" last="Freimer">Nelson B. Freimer</name><affiliation><nlm:aff id="A65">Center for Neurobehavioral Genetics, University of California, Los Angeles, USA.</nlm:aff></affiliation></author><author><name sortKey="Gill, Michael" sort="Gill, Michael" uniqKey="Gill M" first="Michael" last="Gill">Michael Gill</name><affiliation><nlm:aff id="A46">Neuropsychiatric Genetics Research Group, Department of Psychiatry, Institute for Molecular Medicine, Trinity College, Dublin, Ireland.</nlm:aff></affiliation><affiliation><nlm:aff id="A47">Trinity College Institute of Neuroscience, Trinity College, Dublin, Ireland.</nlm:aff></affiliation></author><author><name sortKey="Goring, Harald H H" sort="Goring, Harald H H" uniqKey="Goring H" first="Harald H H" last="Göring">Harald H H. Göring</name><affiliation><nlm:aff id="A64">Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA.</nlm:aff></affiliation></author><author><name sortKey="Hagler, Donald J" sort="Hagler, Donald J" uniqKey="Hagler D" first="Donald J" last="Hagler">Donald J. Hagler</name><affiliation><nlm:aff id="A70">Department of Radiology, University of California, San Diego, La Jolla, California, USA.</nlm:aff></affiliation></author><author><name sortKey="Hoehn, David" sort="Hoehn, David" uniqKey="Hoehn D" first="David" last="Hoehn">David Hoehn</name><affiliation><nlm:aff id="A49">Max Planck Institute of Psychiatry, Munich, Germany.</nlm:aff></affiliation></author><author><name sortKey="Holsboer, Florian" sort="Holsboer, Florian" uniqKey="Holsboer F" first="Florian" last="Holsboer">Florian Holsboer</name><affiliation><nlm:aff id="A49">Max Planck Institute of Psychiatry, Munich, Germany.</nlm:aff></affiliation></author><author><name sortKey="Hoogman, Martine" sort="Hoogman, Martine" uniqKey="Hoogman M" first="Martine" last="Hoogman">Martine Hoogman</name><affiliation><nlm:aff id="A5">Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A7">Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A71">Department of Cognitive Neuroscience, Radboud University Nijmegen Medical Centre, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A72">Max Planck Institute for Psycholinguistics, Nijmegen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Hosten, Norbert" sort="Hosten, Norbert" uniqKey="Hosten N" first="Norbert" last="Hosten">Norbert Hosten</name><affiliation><nlm:aff id="A24">Department of Diagnostic Radiology and Neuroradiology, University of Greifswald, Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Jahanshad, Neda" sort="Jahanshad, Neda" uniqKey="Jahanshad N" first="Neda" last="Jahanshad">Neda Jahanshad</name><affiliation><nlm:aff id="A1">Laboratory of Neuro Imaging, David Geffen School of Medicine, University of California, Los Angeles, California, USA.</nlm:aff></affiliation></author><author><name sortKey="Johnson, Matthew P" sort="Johnson, Matthew P" uniqKey="Johnson M" first="Matthew P" last="Johnson">Matthew P. Johnson</name><affiliation><nlm:aff id="A64">Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA.</nlm:aff></affiliation></author><author><name sortKey="Kasperaviciute, Dalia" sort="Kasperaviciute, Dalia" uniqKey="Kasperaviciute D" first="Dalia" last="Kasperaviciute">Dalia Kasperaviciute</name><affiliation><nlm:aff id="A73">Department of Clinical and Experimental Epilepsy, University College London, Institute of Neurology, London, UK.</nlm:aff></affiliation></author><author><name sortKey="Kent, Jack W" sort="Kent, Jack W" uniqKey="Kent J" first="Jack W" last="Kent">Jack W. Kent</name><affiliation><nlm:aff id="A64">Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA.</nlm:aff></affiliation></author><author><name sortKey="Kochunov, Peter" sort="Kochunov, Peter" uniqKey="Kochunov P" first="Peter" last="Kochunov">Peter Kochunov</name><affiliation><nlm:aff id="A69">Research Imaging Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A74">Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, Maryland, USA.</nlm:aff></affiliation></author><author><name sortKey="Lancaster, Jack L" sort="Lancaster, Jack L" uniqKey="Lancaster J" first="Jack L" last="Lancaster">Jack L. Lancaster</name><affiliation><nlm:aff id="A69">Research Imaging Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.</nlm:aff></affiliation></author><author><name sortKey="Lawrie, Stephen M" sort="Lawrie, Stephen M" uniqKey="Lawrie S" first="Stephen M" last="Lawrie">Stephen M. Lawrie</name><affiliation><nlm:aff id="A48">Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Liewald, David C" sort="Liewald, David C" uniqKey="Liewald D" first="David C" last="Liewald">David C. Liewald</name><affiliation><nlm:aff id="A30">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Mandl, Rene" sort="Mandl, Rene" uniqKey="Mandl R" first="René" last="Mandl">René Mandl</name><affiliation><nlm:aff id="A15">Department of Psychiatry, Rudolf Magnus Institute, University Medical Center Utrecht, Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Matarin, Mar" sort="Matarin, Mar" uniqKey="Matarin M" first="Mar" last="Matarin">Mar Matarin</name><affiliation><nlm:aff id="A73">Department of Clinical and Experimental Epilepsy, University College London, Institute of Neurology, London, UK.</nlm:aff></affiliation></author><author><name sortKey="Mattheisen, Manuel" sort="Mattheisen, Manuel" uniqKey="Mattheisen M" first="Manuel" last="Mattheisen">Manuel Mattheisen</name><affiliation><nlm:aff id="A75">Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A76">Institute of Human Genetics, University of Bonn, Bonn, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A77">Institute for Genomic Mathematics, University of Bonn, Bonn, Germany.</nlm:aff></affiliation></author><author><name sortKey="Meisenzahl, Eva" sort="Meisenzahl, Eva" uniqKey="Meisenzahl E" first="Eva" last="Meisenzahl">Eva Meisenzahl</name><affiliation><nlm:aff id="A78">Department of Psychiatry, Ludwig-Maximilians-University (LMU), Munich, Germany.</nlm:aff></affiliation></author><author><name sortKey="Melle, Ingrid" sort="Melle, Ingrid" uniqKey="Melle I" first="Ingrid" last="Melle">Ingrid Melle</name><affiliation><nlm:aff id="A16">Institute of Clinical Medicine, University of Oslo, Oslo, Norway.</nlm:aff></affiliation><affiliation><nlm:aff id="A79">Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.</nlm:aff></affiliation></author><author><name sortKey="Moses, Eric K" sort="Moses, Eric K" uniqKey="Moses E" first="Eric K" last="Moses">Eric K. Moses</name><affiliation><nlm:aff id="A64">Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA.</nlm:aff></affiliation></author><author><name sortKey="Muhleisen, Thomas W" sort="Muhleisen, Thomas W" uniqKey="Muhleisen T" first="Thomas W" last="Mühleisen">Thomas W. Mühleisen</name><affiliation><nlm:aff id="A75">Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A76">Institute of Human Genetics, University of Bonn, Bonn, Germany.</nlm:aff></affiliation></author><author><name sortKey="Nauck, Matthias" sort="Nauck, Matthias" uniqKey="Nauck M" first="Matthias" last="Nauck">Matthias Nauck</name><affiliation><nlm:aff id="A80">Institute of Clinical Chemistry and Laboratory Medicine, University of Greifswald, Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Nothen, Markus M" sort="Nothen, Markus M" uniqKey="Nothen M" first="Markus M" last="Nöthen">Markus M. Nöthen</name><affiliation><nlm:aff id="A75">Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A76">Institute of Human Genetics, University of Bonn, Bonn, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A81">German Center for Neurodegenerative Disorders (DZNE), Bonn, Germany.</nlm:aff></affiliation></author><author><name sortKey="Olvera, Rene L" sort="Olvera, Rene L" uniqKey="Olvera R" first="Rene L" last="Olvera">Rene L. Olvera</name><affiliation><nlm:aff id="A82">Department of Psychiatry, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.</nlm:aff></affiliation></author><author><name sortKey="Pandolfo, Massimo" sort="Pandolfo, Massimo" uniqKey="Pandolfo M" first="Massimo" last="Pandolfo">Massimo Pandolfo</name><affiliation><nlm:aff id="A67">Department of Neurology, Hopital Erasme, Universite Libre de Bruxelles, Brussels, Belgium.</nlm:aff></affiliation></author><author><name sortKey="Pike, G Bruce" sort="Pike, G Bruce" uniqKey="Pike G" first="G Bruce" last="Pike">G Bruce Pike</name><affiliation><nlm:aff id="A83">Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.</nlm:aff></affiliation></author><author><name sortKey="Puls, Ralf" sort="Puls, Ralf" uniqKey="Puls R" first="Ralf" last="Puls">Ralf Puls</name><affiliation><nlm:aff id="A24">Department of Diagnostic Radiology and Neuroradiology, University of Greifswald, Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Reinvang, Ivar" sort="Reinvang, Ivar" uniqKey="Reinvang I" first="Ivar" last="Reinvang">Ivar Reinvang</name><affiliation><nlm:aff id="A84">Center for the Study of Human Cognition, Department of Psychology, University of Oslo, Oslo, Norway.</nlm:aff></affiliation><affiliation><nlm:aff id="A85">Centre for Advanced Study, Oslo, Norway.</nlm:aff></affiliation></author><author><name sortKey="Renteria, Miguel E" sort="Renteria, Miguel E" uniqKey="Renteria M" first="Miguel E" last="Rentería">Miguel E. Rentería</name><affiliation><nlm:aff id="A2">Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland, Australia.</nlm:aff></affiliation><affiliation><nlm:aff id="A86">School of Psychology, University of Queensland, Brisbane, Queensland, Australia.</nlm:aff></affiliation></author><author><name sortKey="Rietschel, Marcella" sort="Rietschel, Marcella" uniqKey="Rietschel M" first="Marcella" last="Rietschel">Marcella Rietschel</name><affiliation><nlm:aff id="A25">Central Institute of Mental Health, University of Heidelberg–Medical Faculty Mannheim, Mannheim, Germany.</nlm:aff></affiliation></author><author><name sortKey="Roffman, Joshua L" sort="Roffman, Joshua L" uniqKey="Roffman J" first="Joshua L" last="Roffman">Joshua L. Roffman</name><affiliation><nlm:aff id="A37">Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff></affiliation></author><author><name sortKey="Royle, Natalie A" sort="Royle, Natalie A" uniqKey="Royle N" first="Natalie A" last="Royle">Natalie A. Royle</name><affiliation><nlm:aff id="A30">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A42">Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) Collaboration, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A43">Brain Research Imaging Centre, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Rujescu, Dan" sort="Rujescu, Dan" uniqKey="Rujescu D" first="Dan" last="Rujescu">Dan Rujescu</name><affiliation><nlm:aff id="A78">Department of Psychiatry, Ludwig-Maximilians-University (LMU), Munich, Germany.</nlm:aff></affiliation></author><author><name sortKey="Savitz, Jonathan" sort="Savitz, Jonathan" uniqKey="Savitz J" first="Jonathan" last="Savitz">Jonathan Savitz</name><affiliation><nlm:aff id="A45">Section on Neuroimaging in Mood and Anxiety Disorders, Intramural Research Program, NIMH, NIH, US Department of Health and Human Services, Bethesda, Maryland, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A87">Laureate Institute for Brain Research, Tulsa, Oklahoma, USA.</nlm:aff></affiliation></author><author><name sortKey="Schnack, Hugo G" sort="Schnack, Hugo G" uniqKey="Schnack H" first="Hugo G" last="Schnack">Hugo G. Schnack</name><affiliation><nlm:aff id="A15">Department of Psychiatry, Rudolf Magnus Institute, University Medical Center Utrecht, Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Schnell, Knut" sort="Schnell, Knut" uniqKey="Schnell K" first="Knut" last="Schnell">Knut Schnell</name><affiliation><nlm:aff id="A88">Department of General Psychiatry, Heidelberg University Hospital, University of Heidelberg, Heidelberg, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A89">Department of Psychiatry, Division of Medical Psychology, Bonn, Germany.</nlm:aff></affiliation></author><author><name sortKey="Seiferth, Nina" sort="Seiferth, Nina" uniqKey="Seiferth N" first="Nina" last="Seiferth">Nina Seiferth</name><affiliation><nlm:aff id="A41">Department of Psychiatry and Psychotherapy, Charité-Universitaetsmedizin Berlin, Campus Mitte, Berlin, Germany.</nlm:aff></affiliation></author><author><name sortKey="Smith, Colin" sort="Smith, Colin" uniqKey="Smith C" first="Colin" last="Smith">Colin Smith</name><affiliation><nlm:aff id="A90">The MRC Sudden Death Tissue Bank in Edinburgh, Department of Pathology, University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Steen, Vidar M" sort="Steen, Vidar M" uniqKey="Steen V" first="Vidar M" last="Steen">Vidar M. Steen</name><affiliation><nlm:aff id="A22">Dr Einar Martens Research Group for Biological Psychiatry, Department of Clinical Medicine, University of Bergen, Bergen, Norway.</nlm:aff></affiliation><affiliation><nlm:aff id="A23">Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway.</nlm:aff></affiliation></author><author><name sortKey="Valdes Hernandez, Maria C" sort="Valdes Hernandez, Maria C" uniqKey="Valdes Hernandez M" first="Maria C" last="Valdés Hernández">Maria C. Valdés Hernández</name><affiliation><nlm:aff id="A30">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A42">Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) Collaboration, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A43">Brain Research Imaging Centre, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Van Den Heuvel, Martijn" sort="Van Den Heuvel, Martijn" uniqKey="Van Den Heuvel M" first="Martijn" last="Van Den Heuvel">Martijn Van Den Heuvel</name><affiliation><nlm:aff id="A15">Department of Psychiatry, Rudolf Magnus Institute, University Medical Center Utrecht, Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Van Der Wee, Nic J" sort="Van Der Wee, Nic J" uniqKey="Van Der Wee N" first="Nic J" last="Van Der Wee">Nic J. Van Der Wee</name><affiliation><nlm:aff id="A59">Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A60">Leiden Institute for Brain and Cognition, Leiden University, Leiden, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Van Haren, Neeltje E M" sort="Van Haren, Neeltje E M" uniqKey="Van Haren N" first="Neeltje E M" last="Van Haren">Neeltje E M. Van Haren</name><affiliation><nlm:aff id="A15">Department of Psychiatry, Rudolf Magnus Institute, University Medical Center Utrecht, Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Veltman, Joris A" sort="Veltman, Joris A" uniqKey="Veltman J" first="Joris A" last="Veltman">Joris A. Veltman</name><affiliation><nlm:aff id="A5">Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Volzke, Henry" sort="Volzke, Henry" uniqKey="Volzke H" first="Henry" last="Völzke">Henry Völzke</name><affiliation><nlm:aff id="A91">Institute for Community Medicine, University of Greifswald, Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Walker, Robert" sort="Walker, Robert" uniqKey="Walker R" first="Robert" last="Walker">Robert Walker</name><affiliation><nlm:aff id="A90">The MRC Sudden Death Tissue Bank in Edinburgh, Department of Pathology, University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Westlye, Lars T" sort="Westlye, Lars T" uniqKey="Westlye L" first="Lars T" last="Westlye">Lars T. Westlye</name><affiliation><nlm:aff id="A84">Center for the Study of Human Cognition, Department of Psychology, University of Oslo, Oslo, Norway.</nlm:aff></affiliation></author><author><name sortKey="Whelan, Christopher D" sort="Whelan, Christopher D" uniqKey="Whelan C" first="Christopher D" last="Whelan">Christopher D. Whelan</name><affiliation><nlm:aff id="A63">Department of Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.</nlm:aff></affiliation></author><author><name sortKey="Agartz, Ingrid" sort="Agartz, Ingrid" uniqKey="Agartz I" first="Ingrid" last="Agartz">Ingrid Agartz</name><affiliation><nlm:aff id="A16">Institute of Clinical Medicine, University of Oslo, Oslo, Norway.</nlm:aff></affiliation><affiliation><nlm:aff id="A92">Department of Research and Development, Diakonhjemmet Hospital, Oslo, Norway.</nlm:aff></affiliation></author><author><name sortKey="Boomsma, Dorret I" sort="Boomsma, Dorret I" uniqKey="Boomsma D" first="Dorret I" last="Boomsma">Dorret I. Boomsma</name><affiliation><nlm:aff id="A29">Department of Biological Psychology, Neuroscience Campus Amsterdam, VU University, Amsterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Cavalleri, Gianpiero L" sort="Cavalleri, Gianpiero L" uniqKey="Cavalleri G" first="Gianpiero L" last="Cavalleri">Gianpiero L. Cavalleri</name><affiliation><nlm:aff id="A63">Department of Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.</nlm:aff></affiliation></author><author><name sortKey="Dale, Anders M" sort="Dale, Anders M" uniqKey="Dale A" first="Anders M" last="Dale">Anders M. Dale</name><affiliation><nlm:aff id="A53">Department of Neurosciences, University of California, San Diego, La Jolla, California, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A70">Department of Radiology, University of California, San Diego, La Jolla, California, USA.</nlm:aff></affiliation></author><author><name sortKey="Djurovic, Srdjan" sort="Djurovic, Srdjan" uniqKey="Djurovic S" first="Srdjan" last="Djurovic">Srdjan Djurovic</name><affiliation><nlm:aff id="A16">Institute of Clinical Medicine, University of Oslo, Oslo, Norway.</nlm:aff></affiliation><affiliation><nlm:aff id="A93">Department of Medical Genetics, Oslo University Hospital, Oslo, Norway.</nlm:aff></affiliation></author><author><name sortKey="Drevets, Wayne C" sort="Drevets, Wayne C" uniqKey="Drevets W" first="Wayne C" last="Drevets">Wayne C. Drevets</name><affiliation><nlm:aff id="A45">Section on Neuroimaging in Mood and Anxiety Disorders, Intramural Research Program, NIMH, NIH, US Department of Health and Human Services, Bethesda, Maryland, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A87">Laureate Institute for Brain Research, Tulsa, Oklahoma, USA.</nlm:aff></affiliation></author><author><name sortKey="Hagoort, Peter" sort="Hagoort, Peter" uniqKey="Hagoort P" first="Peter" last="Hagoort">Peter Hagoort</name><affiliation><nlm:aff id="A7">Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A52">Donders Centre for Cognitive Neuroimaging, Radboud University Nijmegen, Nijmegen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A72">Max Planck Institute for Psycholinguistics, Nijmegen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Hall, Jeremy" sort="Hall, Jeremy" uniqKey="Hall J" first="Jeremy" last="Hall">Jeremy Hall</name><affiliation><nlm:aff id="A48">Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Heinz, Andreas" sort="Heinz, Andreas" uniqKey="Heinz A" first="Andreas" last="Heinz">Andreas Heinz</name><affiliation><nlm:aff id="A41">Department of Psychiatry and Psychotherapy, Charité-Universitaetsmedizin Berlin, Campus Mitte, Berlin, Germany.</nlm:aff></affiliation></author><author><name sortKey="Jack, Clifford R" sort="Jack, Clifford R" uniqKey="Jack C" first="Clifford R" last="Jack">Clifford R. Jack</name><affiliation><nlm:aff id="A94">Aging and Dementia Imaging Research Laboratory, Department of Radiology, Mayo Clinic and Foundation, Rochester, Minnesota, USA.</nlm:aff></affiliation></author><author><name sortKey="Foroud, Tatiana M" sort="Foroud, Tatiana M" uniqKey="Foroud T" first="Tatiana M" last="Foroud">Tatiana M. Foroud</name><affiliation><nlm:aff id="A34">Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, Indiana, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A95">Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA.</nlm:aff></affiliation></author><author><name sortKey="Le Hellard, Stephanie" sort="Le Hellard, Stephanie" uniqKey="Le Hellard S" first="Stephanie" last="Le Hellard">Stephanie Le Hellard</name><affiliation><nlm:aff id="A22">Dr Einar Martens Research Group for Biological Psychiatry, Department of Clinical Medicine, University of Bergen, Bergen, Norway.</nlm:aff></affiliation><affiliation><nlm:aff id="A23">Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway.</nlm:aff></affiliation></author><author><name sortKey="Macciardi, Fabio" sort="Macciardi, Fabio" uniqKey="Macciardi F" first="Fabio" last="Macciardi">Fabio Macciardi</name><affiliation><nlm:aff id="A51">Department of Psychiatry and Human Behavior, University of California, Irvine, California, USA.</nlm:aff></affiliation></author><author><name sortKey="Montgomery, Grant W" sort="Montgomery, Grant W" uniqKey="Montgomery G" first="Grant W" last="Montgomery">Grant W. Montgomery</name><affiliation><nlm:aff id="A2">Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland, Australia.</nlm:aff></affiliation></author><author><name sortKey="Poline, Jean Baptiste" sort="Poline, Jean Baptiste" uniqKey="Poline J" first="Jean Baptiste" last="Poline">Jean Baptiste Poline</name><affiliation><nlm:aff id="A96">Neurospin, Institut d’Imagerie Biomédicale (I2BM), Commissariat à l’Energie Atomique, Gif-sur-Yvette, France.</nlm:aff></affiliation></author><author><name sortKey="Porteous, David J" sort="Porteous, David J" uniqKey="Porteous D" first="David J" last="Porteous">David J. Porteous</name><affiliation><nlm:aff id="A30">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A97">Medical Genetics Section, Molecular Medicine Centre, Institute of Genetics and Molecular Medicine, The University of Edinburgh, Western General Hospital, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Sisodiya, Sanjay M" sort="Sisodiya, Sanjay M" uniqKey="Sisodiya S" first="Sanjay M" last="Sisodiya">Sanjay M. Sisodiya</name><affiliation><nlm:aff id="A73">Department of Clinical and Experimental Epilepsy, University College London, Institute of Neurology, London, UK.</nlm:aff></affiliation></author><author><name sortKey="Starr, John M" sort="Starr, John M" uniqKey="Starr J" first="John M" last="Starr">John M. Starr</name><affiliation><nlm:aff id="A30">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A98">Geriatric Medicine Unit, The University of Edinburgh, Royal Victoria Hospital, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Sussmann, Jessika" sort="Sussmann, Jessika" uniqKey="Sussmann J" first="Jessika" last="Sussmann">Jessika Sussmann</name><affiliation><nlm:aff id="A48">Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Toga, Arthur W" sort="Toga, Arthur W" uniqKey="Toga A" first="Arthur W" last="Toga">Arthur W. Toga</name><affiliation><nlm:aff id="A1">Laboratory of Neuro Imaging, David Geffen School of Medicine, University of California, Los Angeles, California, USA.</nlm:aff></affiliation></author><author><name sortKey="Veltman, Dick J" sort="Veltman, Dick J" uniqKey="Veltman D" first="Dick J" last="Veltman">Dick J. Veltman</name><affiliation><nlm:aff id="A62">Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Walter, Henrik" sort="Walter, Henrik" uniqKey="Walter H" first="Henrik" last="Walter">Henrik Walter</name><affiliation><nlm:aff id="A41">Department of Psychiatry and Psychotherapy, Charité-Universitaetsmedizin Berlin, Campus Mitte, Berlin, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A89">Department of Psychiatry, Division of Medical Psychology, Bonn, Germany.</nlm:aff></affiliation></author><author><name sortKey="Weiner, Michael W" sort="Weiner, Michael W" uniqKey="Weiner M" first="Michael W" last="Weiner">Michael W. Weiner</name><affiliation><nlm:aff id="A99">Departments of Radiology, University of California, San Francisco, California, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A100">Department of Medicine, University of California, San Francisco, California, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A101">Department of Psychiatry, University of California, San Francisco, California, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A102">Veterans Affairs Medical Center, San Francisco, California, USA.</nlm:aff></affiliation></author><author><name sortKey="Bis, Joshua C" sort="Bis, Joshua C" uniqKey="Bis J" first="Joshua C" last="Bis">Joshua C. Bis</name><affiliation><nlm:aff id="A103">Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA.</nlm:aff></affiliation></author><author><name sortKey="Ikram, M Arfan" sort="Ikram, M Arfan" uniqKey="Ikram M" first="M Arfan" last="Ikram">M Arfan Ikram</name><affiliation><nlm:aff id="A104">Department of Epidemiology, Erasmus Medical Center University Medical Center, Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A105">Department of Radiology, Erasmus Medical Center University Medical Center, Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A106">Netherlands Consortium for Healthy Aging, Leiden, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Smith, Albert V" sort="Smith, Albert V" uniqKey="Smith A" first="Albert V" last="Smith">Albert V. Smith</name><affiliation><nlm:aff id="A107">Icelandic Heart Association, Kopavogur, Iceland.</nlm:aff></affiliation><affiliation><nlm:aff id="A108">Faculty of Medicine, University of Iceland, Reykjavik, Iceland.</nlm:aff></affiliation></author><author><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name><affiliation><nlm:aff id="A107">Icelandic Heart Association, Kopavogur, Iceland.</nlm:aff></affiliation><affiliation><nlm:aff id="A108">Faculty of Medicine, University of Iceland, Reykjavik, Iceland.</nlm:aff></affiliation></author><author><name sortKey="Tzourio, Christophe" sort="Tzourio, Christophe" uniqKey="Tzourio C" first="Christophe" last="Tzourio">Christophe Tzourio</name><affiliation><nlm:aff id="A109">University of Bordeaux, U708, Bordeaux, France.</nlm:aff></affiliation><affiliation><nlm:aff id="A110">Institut National de la Santé et la Recherche Médicale (INSERM), Neuroepidemiology, U708, Bordeaux, France.</nlm:aff></affiliation></author><author><name sortKey="Vernooij, Meike W" sort="Vernooij, Meike W" uniqKey="Vernooij M" first="Meike W" last="Vernooij">Meike W. Vernooij</name><affiliation><nlm:aff id="A104">Department of Epidemiology, Erasmus Medical Center University Medical Center, Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A105">Department of Radiology, Erasmus Medical Center University Medical Center, Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A106">Netherlands Consortium for Healthy Aging, Leiden, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Launer, Lenore J" sort="Launer, Lenore J" uniqKey="Launer L" first="Lenore J" last="Launer">Lenore J. Launer</name><affiliation><nlm:aff id="A111">Laboratory of Epidemiology, Demography, and Biometry, NIH, Bethesda, Maryland, USA.</nlm:aff></affiliation></author><author><name sortKey="Decarli, Charles" sort="Decarli, Charles" uniqKey="Decarli C" first="Charles" last="Decarli">Charles Decarli</name><affiliation><nlm:aff id="A112">Department of Neurology, University of California, Davis, Sacramento, California, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A113">Center of Neuroscience, University of California, Davis, Sacramento, California, USA.</nlm:aff></affiliation></author><author><name sortKey="Seshadri, Sudha" sort="Seshadri, Sudha" uniqKey="Seshadri S" first="Sudha" last="Seshadri">Sudha Seshadri</name><affiliation><nlm:aff id="A114">Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A115">National Heart, Lung, and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts, USA.</nlm:aff></affiliation></author><author><name sortKey="Andreassen, Ole A" sort="Andreassen, Ole A" uniqKey="Andreassen O" first="Ole A" last="Andreassen">Ole A. Andreassen</name><affiliation><nlm:aff id="A16">Institute of Clinical Medicine, University of Oslo, Oslo, Norway.</nlm:aff></affiliation><affiliation><nlm:aff id="A79">Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.</nlm:aff></affiliation></author><author><name sortKey="Apostolova, Liana G" sort="Apostolova, Liana G" uniqKey="Apostolova L" first="Liana G" last="Apostolova">Liana G. Apostolova</name><affiliation><nlm:aff id="A1">Laboratory of Neuro Imaging, David Geffen School of Medicine, University of California, Los Angeles, California, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A32">Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, California, USA.</nlm:aff></affiliation></author><author><name sortKey="Bastin, Mark E" sort="Bastin, Mark E" uniqKey="Bastin M" first="Mark E" last="Bastin">Mark E. Bastin</name><affiliation><nlm:aff id="A30">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A42">Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) Collaboration, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A43">Brain Research Imaging Centre, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A116">Division of Health Sciences (Medical Physics), The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Blangero, John" sort="Blangero, John" uniqKey="Blangero J" first="John" last="Blangero">John Blangero</name><affiliation><nlm:aff id="A64">Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA.</nlm:aff></affiliation></author><author><name sortKey="Brunner, Han G" sort="Brunner, Han G" uniqKey="Brunner H" first="Han G" last="Brunner">Han G. Brunner</name><affiliation><nlm:aff id="A5">Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Buckner, Randy L" sort="Buckner, Randy L" uniqKey="Buckner R" first="Randy L" last="Buckner">Randy L. Buckner</name><affiliation><nlm:aff id="A26">Department of Psychology, Center for Brain Science, Harvard University, Cambridge, Massachusetts, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A27">Howard Hughes Medical Institute, Cambridge, Massachusetts, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A37">Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A68">Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff></affiliation></author><author><name sortKey="Cichon, Sven" sort="Cichon, Sven" uniqKey="Cichon S" first="Sven" last="Cichon">Sven Cichon</name><affiliation><nlm:aff id="A75">Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A76">Institute of Human Genetics, University of Bonn, Bonn, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A117">Institute for Neuroscience and Medicine (INM-1), Research Center Juelich, Juelich, Germany.</nlm:aff></affiliation></author><author><name sortKey="Coppola, Giovanni" sort="Coppola, Giovanni" uniqKey="Coppola G" first="Giovanni" last="Coppola">Giovanni Coppola</name><affiliation><nlm:aff id="A32">Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, California, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A118">Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, California, USA.</nlm:aff></affiliation></author><author><name sortKey="De Zubicaray, Greig I" sort="De Zubicaray, Greig I" uniqKey="De Zubicaray G" first="Greig I" last="De Zubicaray">Greig I. De Zubicaray</name><affiliation><nlm:aff id="A86">School of Psychology, University of Queensland, Brisbane, Queensland, Australia.</nlm:aff></affiliation></author><author><name sortKey="Deary, Ian J" sort="Deary, Ian J" uniqKey="Deary I" first="Ian J" last="Deary">Ian J. Deary</name><affiliation><nlm:aff id="A30">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A31">Department of Psychology, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Donohoe, Gary" sort="Donohoe, Gary" uniqKey="Donohoe G" first="Gary" last="Donohoe">Gary Donohoe</name><affiliation><nlm:aff id="A46">Neuropsychiatric Genetics Research Group, Department of Psychiatry, Institute for Molecular Medicine, Trinity College, Dublin, Ireland.</nlm:aff></affiliation><affiliation><nlm:aff id="A47">Trinity College Institute of Neuroscience, Trinity College, Dublin, Ireland.</nlm:aff></affiliation></author><author><name sortKey="De Geus, Eco J C" sort="De Geus, Eco J C" uniqKey="De Geus E" first="Eco J C" last="De Geus">Eco J C. De Geus</name><affiliation><nlm:aff id="A29">Department of Biological Psychology, Neuroscience Campus Amsterdam, VU University, Amsterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Espeseth, Thomas" sort="Espeseth, Thomas" uniqKey="Espeseth T" first="Thomas" last="Espeseth">Thomas Espeseth</name><affiliation><nlm:aff id="A84">Center for the Study of Human Cognition, Department of Psychology, University of Oslo, Oslo, Norway.</nlm:aff></affiliation><affiliation><nlm:aff id="A85">Centre for Advanced Study, Oslo, Norway.</nlm:aff></affiliation><affiliation><nlm:aff id="A119">Department of Biological and Medical Psychology, Faculty of Psychology, University of Bergen, Bergen, Norway.</nlm:aff></affiliation></author><author><name sortKey="Fernandez, Guillen" sort="Fernandez, Guillen" uniqKey="Fernandez G" first="Guillén" last="Fernández">Guillén Fernández</name><affiliation><nlm:aff id="A7">Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A52">Donders Centre for Cognitive Neuroimaging, Radboud University Nijmegen, Nijmegen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A71">Department of Cognitive Neuroscience, Radboud University Nijmegen Medical Centre, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Glahn, David C" sort="Glahn, David C" uniqKey="Glahn D" first="David C" last="Glahn">David C. Glahn</name><affiliation><nlm:aff id="A8">Olin Neuropsychiatry Research Center, Institute of Living, Hartford Hospital, Hartford, Connecticut, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A9">Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA.</nlm:aff></affiliation></author><author><name sortKey="Grabe, Hans J" sort="Grabe, Hans J" uniqKey="Grabe H" first="Hans J" last="Grabe">Hans J. Grabe</name><affiliation><nlm:aff id="A13">Department of Psychiatry and Psychotherapy, University of Greifswald, Greifswald, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A120">German Center for Neurodegenerative Diseases (DZNE), Rostock/Greifswald, Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Hardy, John" sort="Hardy, John" uniqKey="Hardy J" first="John" last="Hardy">John Hardy</name><affiliation><nlm:aff id="A54">Department of Molecular Neuroscience, University College London, London, UK.</nlm:aff></affiliation></author><author><name sortKey="Hulshoff Pol, Hilleke E" sort="Hulshoff Pol, Hilleke E" uniqKey="Hulshoff Pol H" first="Hilleke E" last="Hulshoff Pol">Hilleke E. Hulshoff Pol</name><affiliation><nlm:aff id="A15">Department of Psychiatry, Rudolf Magnus Institute, University Medical Center Utrecht, Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Jenkinson, Mark" sort="Jenkinson, Mark" uniqKey="Jenkinson M" first="Mark" last="Jenkinson">Mark Jenkinson</name><affiliation><nlm:aff id="A121">Functional Magnetic Resonance Imaging of the Brain (FMRIB) Centre, Oxford University, Oxford, UK.</nlm:aff></affiliation></author><author><name sortKey="Kahn, Rene S" sort="Kahn, Rene S" uniqKey="Kahn R" first="René S" last="Kahn">René S. Kahn</name><affiliation><nlm:aff id="A15">Department of Psychiatry, Rudolf Magnus Institute, University Medical Center Utrecht, Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Mcdonald, Colm" sort="Mcdonald, Colm" uniqKey="Mcdonald C" first="Colm" last="Mcdonald">Colm Mcdonald</name><affiliation><nlm:aff id="A20">Clinical Neuroimaging Laboratory, Department of Psychiatry, National University of Ireland Galway, Galway, Ireland.</nlm:aff></affiliation></author><author><name sortKey="Mcintosh, Andrew M" sort="Mcintosh, Andrew M" uniqKey="Mcintosh A" first="Andrew M" last="Mcintosh">Andrew M. Mcintosh</name><affiliation><nlm:aff id="A48">Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Mcmahon, Francis J" sort="Mcmahon, Francis J" uniqKey="Mcmahon F" first="Francis J" last="Mcmahon">Francis J. Mcmahon</name><affiliation><nlm:aff id="A35">Mood and Anxiety Disorders Section, Human Genetics Branch, Intramural Research Program, National Institute of Mental Health (NIMH), US National Institutes of Health (NIH), US Department of Health and Human Services, Bethesda, Maryland, USA.</nlm:aff></affiliation></author><author><name sortKey="Mcmahon, Katie L" sort="Mcmahon, Katie L" uniqKey="Mcmahon K" first="Katie L" last="Mcmahon">Katie L. Mcmahon</name><affiliation><nlm:aff id="A122">Centre for Advanced Imaging, University of Queensland, Brisbane, Queensland, Australia.</nlm:aff></affiliation></author><author><name sortKey="Meyer Lindenberg, Andreas" sort="Meyer Lindenberg, Andreas" uniqKey="Meyer Lindenberg A" first="Andreas" last="Meyer-Lindenberg">Andreas Meyer-Lindenberg</name><affiliation><nlm:aff id="A25">Central Institute of Mental Health, University of Heidelberg–Medical Faculty Mannheim, Mannheim, Germany.</nlm:aff></affiliation></author><author><name sortKey="Morris, Derek W" sort="Morris, Derek W" uniqKey="Morris D" first="Derek W" last="Morris">Derek W. Morris</name><affiliation><nlm:aff id="A46">Neuropsychiatric Genetics Research Group, Department of Psychiatry, Institute for Molecular Medicine, Trinity College, Dublin, Ireland.</nlm:aff></affiliation><affiliation><nlm:aff id="A47">Trinity College Institute of Neuroscience, Trinity College, Dublin, Ireland.</nlm:aff></affiliation></author><author><name sortKey="Muller Myhsok, Bertram" sort="Muller Myhsok, Bertram" uniqKey="Muller Myhsok B" first="Bertram" last="Müller-Myhsok">Bertram Müller-Myhsok</name><affiliation><nlm:aff id="A49">Max Planck Institute of Psychiatry, Munich, Germany.</nlm:aff></affiliation></author><author><name sortKey="Nichols, Thomas E" sort="Nichols, Thomas E" uniqKey="Nichols T" first="Thomas E" last="Nichols">Thomas E. Nichols</name><affiliation><nlm:aff id="A121">Functional Magnetic Resonance Imaging of the Brain (FMRIB) Centre, Oxford University, Oxford, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A123">Department of Statistics, University of Warwick, Coventry, UK.</nlm:aff></affiliation></author><author><name sortKey="Ophoff, Roel A" sort="Ophoff, Roel A" uniqKey="Ophoff R" first="Roel A" last="Ophoff">Roel A. Ophoff</name><affiliation><nlm:aff id="A15">Department of Psychiatry, Rudolf Magnus Institute, University Medical Center Utrecht, Utrecht, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A65">Center for Neurobehavioral Genetics, University of California, Los Angeles, USA.</nlm:aff></affiliation></author><author><name sortKey="Paus, Tomas" sort="Paus, Tomas" uniqKey="Paus T" first="Tomas" last="Paus">Tomas Paus</name><affiliation><nlm:aff id="A21">Rotman Research Institute, University of Toronto, Toronto, Ontario, Canada.</nlm:aff></affiliation></author><author><name sortKey="Pausova, Zdenka" sort="Pausova, Zdenka" uniqKey="Pausova Z" first="Zdenka" last="Pausova">Zdenka Pausova</name><affiliation><nlm:aff id="A17">The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.</nlm:aff></affiliation></author><author><name sortKey="Penninx, Brenda W" sort="Penninx, Brenda W" uniqKey="Penninx B" first="Brenda W" last="Penninx">Brenda W. Penninx</name><affiliation><nlm:aff id="A59">Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A60">Leiden Institute for Brain and Cognition, Leiden University, Leiden, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A62">Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A124">Department of Psychiatry, University Medical Center Groningen, Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Potkin, Steven G" sort="Potkin, Steven G" uniqKey="Potkin S" first="Steven G" last="Potkin">Steven G. Potkin</name><affiliation><nlm:aff id="A51">Department of Psychiatry and Human Behavior, University of California, Irvine, California, USA.</nlm:aff></affiliation></author><author><name sortKey="S Mann, Philipp G" sort="S Mann, Philipp G" uniqKey="S Mann P" first="Philipp G" last="S Mann">Philipp G. S Mann</name><affiliation><nlm:aff id="A49">Max Planck Institute of Psychiatry, Munich, Germany.</nlm:aff></affiliation></author><author><name sortKey="Saykin, Andrew J" sort="Saykin, Andrew J" uniqKey="Saykin A" first="Andrew J" last="Saykin">Andrew J. Saykin</name><affiliation><nlm:aff id="A33">Department of Radiology and Imaging Sciences, Center for Neuroimaging, Indiana University School of Medicine, Indianapolis, Indiana, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A34">Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, Indiana, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A95">Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA.</nlm:aff></affiliation></author><author><name sortKey="Schumann, Gunter" sort="Schumann, Gunter" uniqKey="Schumann G" first="Gunter" last="Schumann">Gunter Schumann</name><affiliation><nlm:aff id="A39">Medical Research Council (MRC)–Social, Genetic and Developmental Psychiatry (SGDP) Centre, Institute of Psychiatry, King’s College London, London, UK.</nlm:aff></affiliation></author><author><name sortKey="Smoller, Jordan W" sort="Smoller, Jordan W" uniqKey="Smoller J" first="Jordan W" last="Smoller">Jordan W. Smoller</name><affiliation><nlm:aff id="A36">Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A37">Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff></affiliation></author><author><name sortKey="Wardlaw, Joanna M" sort="Wardlaw, Joanna M" uniqKey="Wardlaw J" first="Joanna M" last="Wardlaw">Joanna M. Wardlaw</name><affiliation><nlm:aff id="A30">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A42">Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) Collaboration, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A43">Brain Research Imaging Centre, The University of Edinburgh, Edinburgh, UK.</nlm:aff></affiliation></author><author><name sortKey="Weale, Michael E" sort="Weale, Michael E" uniqKey="Weale M" first="Michael E" last="Weale">Michael E. Weale</name><affiliation><nlm:aff id="A50">Department of Medical & Molecular Genetics, King’s College London, London, UK.</nlm:aff></affiliation></author><author><name sortKey="Martin, Nicholas G" sort="Martin, Nicholas G" uniqKey="Martin N" first="Nicholas G" last="Martin">Nicholas G. Martin</name><affiliation><nlm:aff id="A2">Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland, Australia.</nlm:aff></affiliation></author><author><name sortKey="Franke, Barbara" sort="Franke, Barbara" uniqKey="Franke B" first="Barbara" last="Franke">Barbara Franke</name><affiliation><nlm:aff id="A5">Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A6">Department of Psychiatry, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A7">Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Wright, Margaret J" sort="Wright, Margaret J" uniqKey="Wright M" first="Margaret J" last="Wright">Margaret J. Wright</name><affiliation><nlm:aff id="A2">Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland, Australia.</nlm:aff></affiliation></author><author><name sortKey="Thompson, Paul M" sort="Thompson, Paul M" uniqKey="Thompson P" first="Paul M" last="Thompson">Paul M. Thompson</name><affiliation><nlm:aff id="A1">Laboratory of Neuro Imaging, David Geffen School of Medicine, University of California, Los Angeles, California, USA.</nlm:aff></affiliation></author></analytic><series><title level="j">Nature genetics</title><idno type="ISSN">1061-4036</idno><idno type="eISSN">1546-1718</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P5">Identifying genetic variants influencing human brain structures may reveal new biological mechanisms underlying cognition and neuropsychiatric illness. The volume of the hippocampus is a biomarker of incipient Alzheimer’s disease<sup><xref ref-type="bibr" rid="R1">1</xref>,<xref ref-type="bibr" rid="R2">2</xref></sup> and is reduced in schizophrenia<sup><xref ref-type="bibr" rid="R3">3</xref></sup>, major depression<sup><xref ref-type="bibr" rid="R4">4</xref></sup> and mesial temporal lobe epilepsy<sup><xref ref-type="bibr" rid="R5">5</xref></sup>. Whereas many brain imaging phenotypes are highly heritable<sup><xref ref-type="bibr" rid="R6">6</xref>,<xref ref-type="bibr" rid="R7">7</xref></sup>, identifying and replicating genetic influences has been difficult, as small effects and the high costs of magnetic resonance imaging (MRI) have led to underpowered studies. Here we report genome-wide association meta-analyses and replication for mean bilateral hippocampal, total brain and intracranial volumes from a large multinational consortium. The intergenic variant rs7294919 was associated with hippocampal volume (12q24.22; <italic>N</italic> = 21,151; <italic>P</italic> = 6.70 × 10<sup>−16</sup>) and the expression levels of the positional candidate gene <italic>TESC</italic> in brain tissue. Additionally, rs10784502, located within <italic>HMGA2</italic>, was associated with intracranial volume (12q14.3; <italic>N</italic> = 15,782; <italic>P</italic> = 1.12 × 10<sup>−12</sup>). We also identified a suggestive association with total brain volume at rs10494373 within <italic>DDR2</italic> (1q23.3; <italic>N</italic> = 6,500; <italic>P</italic> = 5.81 × 10<sup>−7</sup>).</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
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Genet.</journal-id><journal-title-group><journal-title>Nature genetics</journal-title></journal-title-group><issn pub-type="ppub">1061-4036</issn><issn pub-type="epub">1546-1718</issn></journal-meta><article-meta><article-id pub-id-type="pmid">22504417</article-id><article-id pub-id-type="pmc">3635491</article-id><article-id pub-id-type="doi">10.1038/ng.2250</article-id><article-id pub-id-type="manuscript">NIHMS378125</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Identification of common variants associated with human hippocampal and intracranial volumes</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Stein</surname><given-names>Jason L</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref ref-type="author-notes" rid="FN3">127</xref></contrib><contrib contrib-type="author"><name><surname>Medland</surname><given-names>Sarah 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rid="A43">43</xref></contrib><contrib contrib-type="author"><name><surname>Weale</surname><given-names>Michael E</given-names></name><xref ref-type="aff" rid="A50">50</xref></contrib><contrib contrib-type="author"><name><surname>Martin</surname><given-names>Nicholas G</given-names></name><xref ref-type="aff" rid="A2">2</xref><xref ref-type="author-notes" rid="FN4">128</xref></contrib><contrib contrib-type="author"><name><surname>Franke</surname><given-names>Barbara</given-names></name><xref ref-type="aff" rid="A5">5</xref><xref ref-type="aff" rid="A6">6</xref><xref ref-type="aff" rid="A7">7</xref><xref ref-type="author-notes" rid="FN4">128</xref></contrib><contrib contrib-type="author"><name><surname>Wright</surname><given-names>Margaret J</given-names></name><xref ref-type="aff" rid="A2">2</xref><xref ref-type="author-notes" rid="FN4">128</xref></contrib><contrib contrib-type="author"><name><surname>Thompson</surname><given-names>Paul M</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref ref-type="author-notes" rid="FN4">128</xref></contrib><contrib contrib-type="author"><collab>for the Enhancing Neuro Imaging Genetics through Meta-Analysis (ENIGMA) Consortium</collab><xref ref-type="author-notes" rid="FN2">126</xref></contrib></contrib-group><aff id="A1"><label>1</label>Laboratory of Neuro Imaging, David Geffen School of Medicine, University of California, Los Angeles, California, USA.</aff><aff id="A2"><label>2</label>Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland, Australia.</aff><aff id="A3"><label>3</label>Quantitative Genetics Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland, Australia.</aff><aff id="A4"><label>4</label>Broad Institute of Harvard University and MIT, Cambridge, Massachusetts, USA.</aff><aff id="A5"><label>5</label>Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.</aff><aff id="A6"><label>6</label>Department of Psychiatry, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.</aff><aff id="A7"><label>7</label>Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands.</aff><aff id="A8"><label>8</label>Olin Neuropsychiatry Research Center, Institute of Living, Hartford Hospital, Hartford, Connecticut, USA.</aff><aff id="A9"><label>9</label>Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA.</aff><aff id="A10"><label>10</label>Laboratory of Human Genetics and Cognitive Functions, Institut Pasteur, Paris, France.</aff><aff id="A11"><label>11</label>Centre Nationale de Recherche Scientifique (CNRS) Unité de Recherche Associée (URA) 2182 Genes, Synapses and Cognition, Institut Pasteur, Paris, France.</aff><aff id="A12"><label>12</label>Department of Neuroscience, Université Paris Diderot, Sorbonne Paris Cité, Paris, France.</aff><aff id="A13"><label>13</label>Department of Psychiatry and Psychotherapy, University of Greifswald, Greifswald, Germany.</aff><aff id="A14"><label>14</label>Institute of Psychology, Department of Clinical Psychology and Psychotherapy, University of Heidelberg, Heidelberg, Germany.</aff><aff id="A15"><label>15</label>Department of Psychiatry, Rudolf Magnus Institute, University Medical Center Utrecht, Utrecht, The Netherlands.</aff><aff id="A16"><label>16</label>Institute of Clinical Medicine, University of Oslo, Oslo, Norway.</aff><aff id="A17"><label>17</label>The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.</aff><aff id="A18"><label>18</label>Institute of Basic Medical Sciences, Department of Biostatistics, University of Oslo, Oslo, Norway.</aff><aff id="A19"><label>19</label>Clinical Neuroimaging Laboratory, Department of Anatomy, National University of Ireland Galway, Galway, Ireland.</aff><aff id="A20"><label>20</label>Clinical Neuroimaging Laboratory, Department of Psychiatry, National University of Ireland Galway, Galway, Ireland.</aff><aff id="A21"><label>21</label>Rotman Research Institute, University of Toronto, Toronto, Ontario, Canada.</aff><aff id="A22"><label>22</label>Dr Einar Martens Research Group for Biological Psychiatry, Department of Clinical Medicine, University of Bergen, Bergen, Norway.</aff><aff id="A23"><label>23</label>Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway.</aff><aff id="A24"><label>24</label>Department of Diagnostic Radiology and Neuroradiology, University of Greifswald, Greifswald, Germany.</aff><aff id="A25"><label>25</label>Central Institute of Mental Health, University of Heidelberg–Medical Faculty Mannheim, Mannheim, Germany.</aff><aff id="A26"><label>26</label>Department of Psychology, Center for Brain Science, Harvard University, Cambridge, Massachusetts, USA.</aff><aff id="A27"><label>27</label>Howard Hughes Medical Institute, Cambridge, Massachusetts, USA.</aff><aff id="A28"><label>28</label>Interfaculty Institute for Genetics and Functional Genomics, University of Greifswald, Greifswald, Germany.</aff><aff id="A29"><label>29</label>Department of Biological Psychology, Neuroscience Campus Amsterdam, VU University, Amsterdam, The Netherlands.</aff><aff id="A30"><label>30</label>Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.</aff><aff id="A31"><label>31</label>Department of Psychology, The University of Edinburgh, Edinburgh, UK.</aff><aff id="A32"><label>32</label>Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, California, USA.</aff><aff id="A33"><label>33</label>Department of Radiology and Imaging Sciences, Center for Neuroimaging, Indiana University School of Medicine, Indianapolis, Indiana, USA.</aff><aff id="A34"><label>34</label>Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, Indiana, USA.</aff><aff id="A35"><label>35</label>Mood and Anxiety Disorders Section, Human Genetics Branch, Intramural Research Program, National Institute of Mental Health (NIMH), US National Institutes of Health (NIH), US Department of Health and Human Services, Bethesda, Maryland, USA.</aff><aff id="A36"><label>36</label>Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.</aff><aff id="A37"><label>37</label>Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.</aff><aff id="A38"><label>38</label>Taub Institute for Research on Alzheimer Disease and the Aging Brain, Columbia University Medical Center, New York, New York, USA.</aff><aff id="A39"><label>39</label>Medical Research Council (MRC)–Social, Genetic and Developmental Psychiatry (SGDP) Centre, Institute of Psychiatry, King’s College London, London, UK.</aff><aff id="A40"><label>40</label>Research Unit, Sørlandet Hospital, Kristiansand, Norway.</aff><aff id="A41"><label>41</label>Department of Psychiatry and Psychotherapy, Charité-Universitaetsmedizin Berlin, Campus Mitte, Berlin, Germany.</aff><aff id="A42"><label>42</label>Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) Collaboration, UK.</aff><aff id="A43"><label>43</label>Brain Research Imaging Centre, The University of Edinburgh, Edinburgh, UK.</aff><aff id="A44"><label>44</label>Division of Medical Informatics, Regenstrief Institute, Indianapolis, Indiana, USA.</aff><aff id="A45"><label>45</label>Section on Neuroimaging in Mood and Anxiety Disorders, Intramural Research Program, NIMH, NIH, US Department of Health and Human Services, Bethesda, Maryland, USA.</aff><aff id="A46"><label>46</label>Neuropsychiatric Genetics Research Group, Department of Psychiatry, Institute for Molecular Medicine, Trinity College, Dublin, Ireland.</aff><aff id="A47"><label>47</label>Trinity College Institute of Neuroscience, Trinity College, Dublin, Ireland.</aff><aff id="A48"><label>48</label>Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK.</aff><aff id="A49"><label>49</label>Max Planck Institute of Psychiatry, Munich, Germany.</aff><aff id="A50"><label>50</label>Department of Medical & Molecular Genetics, King’s College London, London, UK.</aff><aff id="A51"><label>51</label>Department of Psychiatry and Human Behavior, University of California, Irvine, California, USA.</aff><aff id="A52"><label>52</label>Donders Centre for Cognitive Neuroimaging, Radboud University Nijmegen, Nijmegen, The Netherlands.</aff><aff id="A53"><label>53</label>Department of Neurosciences, University of California, San Diego, La Jolla, California, USA.</aff><aff id="A54"><label>54</label>Department of Molecular Neuroscience, University College London, London, UK.</aff><aff id="A55"><label>55</label>Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands.</aff><aff id="A56"><label>56</label>Rudolf Magnus Institute, University Medical Center Utrecht, Utrecht, The Netherlands.</aff><aff id="A57"><label>57</label>Department of Genetics, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.</aff><aff id="A58"><label>58</label>Mind Research Network, Albuquerque, New Mexico, USA.</aff><aff id="A59"><label>59</label>Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands.</aff><aff id="A60"><label>60</label>Leiden Institute for Brain and Cognition, Leiden University, Leiden, The Netherlands.</aff><aff id="A61"><label>61</label>Behavioural and Cognitive Neuroscience Neuroimaging Center, University Medical Center Groningen, Groningen, The Netherlands.</aff><aff id="A62"><label>62</label>Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands.</aff><aff id="A63"><label>63</label>Department of Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.</aff><aff id="A64"><label>64</label>Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA.</aff><aff id="A65"><label>65</label>Center for Neurobehavioral Genetics, University of California, Los Angeles, USA.</aff><aff id="A66"><label>66</label>Division of Neurology, Beaumont Hospital, Dublin, Ireland.</aff><aff id="A67"><label>67</label>Department of Neurology, Hopital Erasme, Universite Libre de Bruxelles, Brussels, Belgium.</aff><aff id="A68"><label>68</label>Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, Massachusetts, USA.</aff><aff id="A69"><label>69</label>Research Imaging Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.</aff><aff id="A70"><label>70</label>Department of Radiology, University of California, San Diego, La Jolla, California, USA.</aff><aff id="A71"><label>71</label>Department of Cognitive Neuroscience, Radboud University Nijmegen Medical Centre, The Netherlands.</aff><aff id="A72"><label>72</label>Max Planck Institute for Psycholinguistics, Nijmegen, The Netherlands.</aff><aff id="A73"><label>73</label>Department of Clinical and Experimental Epilepsy, University College London, Institute of Neurology, London, UK.</aff><aff id="A74"><label>74</label>Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, Maryland, USA.</aff><aff id="A75"><label>75</label>Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany.</aff><aff id="A76"><label>76</label>Institute of Human Genetics, University of Bonn, Bonn, Germany.</aff><aff id="A77"><label>77</label>Institute for Genomic Mathematics, University of Bonn, Bonn, Germany.</aff><aff id="A78"><label>78</label>Department of Psychiatry, Ludwig-Maximilians-University (LMU), Munich, Germany.</aff><aff id="A79"><label>79</label>Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.</aff><aff id="A80"><label>80</label>Institute of Clinical Chemistry and Laboratory Medicine, University of Greifswald, Greifswald, Germany.</aff><aff id="A81"><label>81</label>German Center for Neurodegenerative Disorders (DZNE), Bonn, Germany.</aff><aff id="A82"><label>82</label>Department of Psychiatry, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.</aff><aff id="A83"><label>83</label>Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.</aff><aff id="A84"><label>84</label>Center for the Study of Human Cognition, Department of Psychology, University of Oslo, Oslo, Norway.</aff><aff id="A85"><label>85</label>Centre for Advanced Study, Oslo, Norway.</aff><aff id="A86"><label>86</label>School of Psychology, University of Queensland, Brisbane, Queensland, Australia.</aff><aff id="A87"><label>87</label>Laureate Institute for Brain Research, Tulsa, Oklahoma, USA.</aff><aff id="A88"><label>88</label>Department of General Psychiatry, Heidelberg University Hospital, University of Heidelberg, Heidelberg, Germany.</aff><aff id="A89"><label>89</label>Department of Psychiatry, Division of Medical Psychology, Bonn, Germany.</aff><aff id="A90"><label>90</label>The MRC Sudden Death Tissue Bank in Edinburgh, Department of Pathology, University of Edinburgh, Edinburgh, UK.</aff><aff id="A91"><label>91</label>Institute for Community Medicine, University of Greifswald, Greifswald, Germany.</aff><aff id="A92"><label>92</label>Department of Research and Development, Diakonhjemmet Hospital, Oslo, Norway.</aff><aff id="A93"><label>93</label>Department of Medical Genetics, Oslo University Hospital, Oslo, Norway.</aff><aff id="A94"><label>94</label>Aging and Dementia Imaging Research Laboratory, Department of Radiology, Mayo Clinic and Foundation, Rochester, Minnesota, USA.</aff><aff id="A95"><label>95</label>Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA.</aff><aff id="A96"><label>96</label>Neurospin, Institut d’Imagerie Biomédicale (I2BM), Commissariat à l’Energie Atomique, Gif-sur-Yvette, France.</aff><aff id="A97"><label>97</label>Medical Genetics Section, Molecular Medicine Centre, Institute of Genetics and Molecular Medicine, The University of Edinburgh, Western General Hospital, Edinburgh, UK.</aff><aff id="A98"><label>98</label>Geriatric Medicine Unit, The University of Edinburgh, Royal Victoria Hospital, Edinburgh, UK.</aff><aff id="A99"><label>99</label>Departments of Radiology, University of California, San Francisco, California, USA.</aff><aff id="A100"><label>100</label>Department of Medicine, University of California, San Francisco, California, USA.</aff><aff id="A101"><label>101</label>Department of Psychiatry, University of California, San Francisco, California, USA.</aff><aff id="A102"><label>102</label>Veterans Affairs Medical Center, San Francisco, California, USA.</aff><aff id="A103"><label>104</label>Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA.</aff><aff id="A104"><label>105</label>Department of Epidemiology, Erasmus Medical Center University Medical Center, Rotterdam, The Netherlands.</aff><aff id="A105"><label>106</label>Department of Radiology, Erasmus Medical Center University Medical Center, Rotterdam, The Netherlands.</aff><aff id="A106"><label>107</label>Netherlands Consortium for Healthy Aging, Leiden, The Netherlands.</aff><aff id="A107"><label>108</label>Icelandic Heart Association, Kopavogur, Iceland.</aff><aff id="A108"><label>109</label>Faculty of Medicine, University of Iceland, Reykjavik, Iceland.</aff><aff id="A109"><label>110</label>University of Bordeaux, U708, Bordeaux, France.</aff><aff id="A110"><label>111</label>Institut National de la Santé et la Recherche Médicale (INSERM), Neuroepidemiology, U708, Bordeaux, France.</aff><aff id="A111"><label>112</label>Laboratory of Epidemiology, Demography, and Biometry, NIH, Bethesda, Maryland, USA.</aff><aff id="A112"><label>113</label>Department of Neurology, University of California, Davis, Sacramento, California, USA.</aff><aff id="A113"><label>114</label>Center of Neuroscience, University of California, Davis, Sacramento, California, USA.</aff><aff id="A114"><label>115</label>Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA.</aff><aff id="A115"><label>116</label>National Heart, Lung, and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts, USA.</aff><aff id="A116"><label>117</label>Division of Health Sciences (Medical Physics), The University of Edinburgh, Edinburgh, UK.</aff><aff id="A117"><label>118</label>Institute for Neuroscience and Medicine (INM-1), Research Center Juelich, Juelich, Germany.</aff><aff id="A118"><label>119</label>Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, California, USA.</aff><aff id="A119"><label>120</label>Department of Biological and Medical Psychology, Faculty of Psychology, University of Bergen, Bergen, Norway.</aff><aff id="A120"><label>121</label>German Center for Neurodegenerative Diseases (DZNE), Rostock/Greifswald, Greifswald, Germany.</aff><aff id="A121"><label>122</label>Functional Magnetic Resonance Imaging of the Brain (FMRIB) Centre, Oxford University, Oxford, UK.</aff><aff id="A122"><label>123</label>Centre for Advanced Imaging, University of Queensland, Brisbane, Queensland, Australia.</aff><aff id="A123"><label>124</label>Department of Statistics, University of Warwick, Coventry, UK.</aff><aff id="A124"><label>125</label>Department of Psychiatry, University Medical Center Groningen, Groningen, The Netherlands.</aff><author-notes><corresp id="cor1">Correspondence should be addressed to P.M.T. (<email>thompson@loni.ucla.edu</email>)</corresp><fn id="FN1"><label>103</label><p id="P1">A full list of members is provided in the <xref ref-type="supplementary-material" rid="SD3">Supplementary Note</xref>.</p></fn><fn id="FN2"><label>126</label><p id="P2">Information on the consortium is provided in the <xref ref-type="supplementary-material" rid="SD3">Supplementary Note</xref>.</p></fn><fn id="FN3" fn-type="equal"><label>127</label><p id="P3">These authors contributed equally to this work.</p></fn><fn id="FN4"><label>128</label><p id="P4">These authors jointly directed this work.</p></fn></author-notes><pub-date pub-type="nihms-submitted"><day>26</day><month>3</month><year>2013</year></pub-date><pub-date pub-type="epub"><day>15</day><month>4</month><year>2012</year></pub-date><pub-date pub-type="pmc-release"><day>01</day><month>5</month><year>2013</year></pub-date><volume>44</volume><issue>5</issue><fpage>552</fpage><lpage>561</lpage><permissions><copyright-statement>© 2012 Nature America, Inc. All rights reserved.</copyright-statement><copyright-year>2012</copyright-year></permissions><abstract><p id="P5">Identifying genetic variants influencing human brain structures may reveal new biological mechanisms underlying cognition and neuropsychiatric illness. The volume of the hippocampus is a biomarker of incipient Alzheimer’s disease<sup><xref ref-type="bibr" rid="R1">1</xref>,<xref ref-type="bibr" rid="R2">2</xref></sup> and is reduced in schizophrenia<sup><xref ref-type="bibr" rid="R3">3</xref></sup>, major depression<sup><xref ref-type="bibr" rid="R4">4</xref></sup> and mesial temporal lobe epilepsy<sup><xref ref-type="bibr" rid="R5">5</xref></sup>. Whereas many brain imaging phenotypes are highly heritable<sup><xref ref-type="bibr" rid="R6">6</xref>,<xref ref-type="bibr" rid="R7">7</xref></sup>, identifying and replicating genetic influences has been difficult, as small effects and the high costs of magnetic resonance imaging (MRI) have led to underpowered studies. Here we report genome-wide association meta-analyses and replication for mean bilateral hippocampal, total brain and intracranial volumes from a large multinational consortium. The intergenic variant rs7294919 was associated with hippocampal volume (12q24.22; <italic>N</italic> = 21,151; <italic>P</italic> = 6.70 × 10<sup>−16</sup>) and the expression levels of the positional candidate gene <italic>TESC</italic> in brain tissue. Additionally, rs10784502, located within <italic>HMGA2</italic>, was associated with intracranial volume (12q14.3; <italic>N</italic> = 15,782; <italic>P</italic> = 1.12 × 10<sup>−12</sup>). We also identified a suggestive association with total brain volume at rs10494373 within <italic>DDR2</italic> (1q23.3; <italic>N</italic> = 6,500; <italic>P</italic> = 5.81 × 10<sup>−7</sup>).</p></abstract><funding-group><award-group><funding-source country="United States">National Center for Research Resources : NCRR</funding-source><award-id>U24 RR021992 || RR</award-id></award-group><award-group><funding-source country="United States">National Institute on Aging : NIA</funding-source><award-id>U24 AG021886 || AG</award-id></award-group><award-group><funding-source country="United States">National Institute on Aging : NIA</funding-source><award-id>U01 AG024904 || AG</award-id></award-group><award-group><funding-source country="United States">National Institute on Aging : NIA</funding-source><award-id>RC2 AG036535 || AG</award-id></award-group><award-group><funding-source country="United States">National Institute of Mental Health : NIMH</funding-source><award-id>R01 MH083824 || MH</award-id></award-group><award-group><funding-source country="United States">National Institute of Mental Health : NIMH</funding-source><award-id>R01 MH079799 || MH</award-id></award-group><award-group><funding-source country="United States">National Institute of Mental Health : NIMH</funding-source><award-id>R01 MH078111 || MH</award-id></award-group><award-group><funding-source country="United States">National Institute of Mental Health : NIMH</funding-source><award-id>R01 MH059490 || MH</award-id></award-group><award-group><funding-source country="United States">National Institute of Child Health & Human Development : NICHD</funding-source><award-id>R01 HD050735 || HD</award-id></award-group><award-group><funding-source country="United States">National Institute of Biomedical Imaging and Bioengineering : NIBIB</funding-source><award-id>R01 EB008432 || EB</award-id></award-group><award-group><funding-source country="United States">National Institute of Biomedical Imaging and Bioengineering : NIBIB</funding-source><award-id>R01 EB008281 || EB</award-id></award-group><award-group><funding-source country="United States">National Institute on Aging : NIA</funding-source><award-id>R01 AG040060 || AG</award-id></award-group><award-group><funding-source country="United States">National Institute on Aging : NIA</funding-source><award-id>R01 AG020098 || AG</award-id></award-group><award-group><funding-source country="United States">National Institute on Aging : NIA</funding-source><award-id>R01 AG019771 || AG</award-id></award-group><award-group><funding-source country="United States">National Institute on Aging : NIA</funding-source><award-id>P50 AG016570 || AG</award-id></award-group><award-group><funding-source country="United States">National Center for Research Resources : NCRR</funding-source><award-id>P41 RR013642 || RR</award-id></award-group><award-group><funding-source country="United States">National Institute on Aging : NIA</funding-source><award-id>P30 AG010129 || AG</award-id></award-group><award-group><funding-source country="United States">National Institute of Biomedical Imaging and Bioengineering : NIBIB</funding-source><award-id>K01 EB006395 || EB</award-id></award-group><award-group><funding-source country="United States">National Institute on Aging : NIA</funding-source><award-id>K01 AG030514 || AG</award-id></award-group><award-group><funding-source country="United States">National Institute of Mental Health : NIMH</funding-source><award-id>F31 MH087061 || MH</award-id></award-group><award-group><funding-source country="United States">National Center for Research Resources : NCRR</funding-source><award-id>C06 RR017515 || RR</award-id></award-group><award-group><funding-source country="United States">National Center for Research Resources : NCRR</funding-source><award-id>C06 RR013556 || RR</award-id></award-group><award-group><funding-source country="United States">National Institute of Mental Health : NIMH</funding-source><award-id>ZIA MH002810-10 || MH</award-id></award-group></funding-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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