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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">11q13 is a Susceptibility Locus for Hormone Receptor Positive Breast Cancer<xref ref-type="fn" rid="FN3">†</xref>
</title>
<author><name sortKey="Lambrechts, Diether" sort="Lambrechts, Diether" uniqKey="Lambrechts D" first="Diether" last="Lambrechts">Diether Lambrechts</name>
<affiliation><nlm:aff id="A1">Vesalius Research Center (VRC), VIB, KULeuven, Belgium</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Truong, Therese" sort="Truong, Therese" uniqKey="Truong T" first="Therese" last="Truong">Therese Truong</name>
<affiliation><nlm:aff id="A2">Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer Team, Villejuif, France</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A3">University Paris-Sud, UMRS 1018, Villejuif, France</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Justenhoven, Christina" sort="Justenhoven, Christina" uniqKey="Justenhoven C" first="Christina" last="Justenhoven">Christina Justenhoven</name>
<affiliation><nlm:aff id="A4">Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, and University Tübingen, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Humphreys, Manjeet K" sort="Humphreys, Manjeet K" uniqKey="Humphreys M" first="Manjeet K." last="Humphreys">Manjeet K. Humphreys</name>
<affiliation><nlm:aff id="A5">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Wang, Jean" sort="Wang, Jean" uniqKey="Wang J" first="Jean" last="Wang">Jean Wang</name>
<affiliation><nlm:aff id="A5">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hopper, John L" sort="Hopper, John L" uniqKey="Hopper J" first="John L." last="Hopper">John L. Hopper</name>
<affiliation><nlm:aff id="A6">Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Dite, Gillian S" sort="Dite, Gillian S" uniqKey="Dite G" first="Gillian S." last="Dite">Gillian S. Dite</name>
<affiliation><nlm:aff id="A6">Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Apicella, Carmel" sort="Apicella, Carmel" uniqKey="Apicella C" first="Carmel" last="Apicella">Carmel Apicella</name>
<affiliation><nlm:aff id="A6">Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Southey, Melissa C" sort="Southey, Melissa C" uniqKey="Southey M" first="Melissa C." last="Southey">Melissa C. Southey</name>
<affiliation><nlm:aff id="A7">Department of Pathology, The University of Melbourne, Melbourne, Australia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Schmidt, Marjanka K" sort="Schmidt, Marjanka K" uniqKey="Schmidt M" first="Marjanka K." last="Schmidt">Marjanka K. Schmidt</name>
<affiliation><nlm:aff id="A8">Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Broeks, Annegien" sort="Broeks, Annegien" uniqKey="Broeks A" first="Annegien" last="Broeks">Annegien Broeks</name>
<affiliation><nlm:aff id="A8">Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Cornelissen, Sten" sort="Cornelissen, Sten" uniqKey="Cornelissen S" first="Sten" last="Cornelissen">Sten Cornelissen</name>
<affiliation><nlm:aff id="A8">Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Van Hien, Richard" sort="Van Hien, Richard" uniqKey="Van Hien R" first="Richard" last="Van Hien">Richard Van Hien</name>
<affiliation><nlm:aff id="A8">Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Sawyer, Elinor" sort="Sawyer, Elinor" uniqKey="Sawyer E" first="Elinor" last="Sawyer">Elinor Sawyer</name>
<affiliation><nlm:aff id="A9">Division of Cancer Studies, NIHR Comprehensive Biomedical Research Centre, Guy's & St. Thomas' NHS Foundation Trust in partnership with King's College London, London, United Kingdom</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Tomlinson, Ian" sort="Tomlinson, Ian" uniqKey="Tomlinson I" first="Ian" last="Tomlinson">Ian Tomlinson</name>
<affiliation><nlm:aff id="A10">Welcome Trust Centre for Human Genetics and Oxford Biomedical Research Centre, University of Oxford, United Kingdom</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kerin, Michael" sort="Kerin, Michael" uniqKey="Kerin M" first="Michael" last="Kerin">Michael Kerin</name>
<affiliation><nlm:aff id="A11">Clinical Science Institute. University Hospital Galway, Galway, Ireland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Miller, Nicola" sort="Miller, Nicola" uniqKey="Miller N" first="Nicola" last="Miller">Nicola Miller</name>
<affiliation><nlm:aff id="A11">Clinical Science Institute. University Hospital Galway, Galway, Ireland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Milne, Roger L" sort="Milne, Roger L" uniqKey="Milne R" first="Roger L." last="Milne">Roger L. Milne</name>
<affiliation><nlm:aff id="A12">Genetic and Molecular Epidemiology Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Zamora, M Pilar" sort="Zamora, M Pilar" uniqKey="Zamora M" first="M. Pilar" last="Zamora">M. Pilar Zamora</name>
<affiliation><nlm:aff id="A13">Servicio de Oncología Médica, Hospital Universitario La Paz, Madrid, Spain</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Arias Perez, Jose Ignacio" sort="Arias Perez, Jose Ignacio" uniqKey="Arias Perez J" first="José Ignacio" last="Arias Pérez">José Ignacio Arias Pérez</name>
<affiliation><nlm:aff id="A14">Servicio de Cirugía General y Especialidades, Hospital Monte Naranco, Oviedo, Spain</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Benitez, Javier" sort="Benitez, Javier" uniqKey="Benitez J" first="Javier" last="Benítez">Javier Benítez</name>
<affiliation><nlm:aff id="A15">Human Genetics Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hamann, Ute" sort="Hamann, Ute" uniqKey="Hamann U" first="Ute" last="Hamann">Ute Hamann</name>
<affiliation><nlm:aff id="A16">Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ko, Yon Dschun" sort="Ko, Yon Dschun" uniqKey="Ko Y" first="Yon-Dschun" last="Ko">Yon-Dschun Ko</name>
<affiliation><nlm:aff id="A17">Department of Internal Medicine, Evangelische Kliniken Bonn gGmbH, Johanniter Krankenhaus, Bonn, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Bruning, Thomas" sort="Bruning, Thomas" uniqKey="Bruning T" first="Thomas" last="Brüning">Thomas Brüning</name>
<affiliation><nlm:aff id="A18">Institute for Prevention and Occupational Medicine of the German Social Accident Insurance (IPA), Bochum, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Chang Claude, Jenny" sort="Chang Claude, Jenny" uniqKey="Chang Claude J" first="Jenny" last="Chang-Claude">Jenny Chang-Claude</name>
<affiliation><nlm:aff id="A20">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Eilber, Ursel" sort="Eilber, Ursel" uniqKey="Eilber U" first="Ursel" last="Eilber">Ursel Eilber</name>
<affiliation><nlm:aff id="A20">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hein, Rebecca" sort="Hein, Rebecca" uniqKey="Hein R" first="Rebecca" last="Hein">Rebecca Hein</name>
<affiliation><nlm:aff id="A20">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Nickels, Stefan" sort="Nickels, Stefan" uniqKey="Nickels S" first="Stefan" last="Nickels">Stefan Nickels</name>
<affiliation><nlm:aff id="A20">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Flesch Janys, Dieter" sort="Flesch Janys, Dieter" uniqKey="Flesch Janys D" first="Dieter" last="Flesch-Janys">Dieter Flesch-Janys</name>
<affiliation><nlm:aff id="A21">Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Wang Gohrke, Shan" sort="Wang Gohrke, Shan" uniqKey="Wang Gohrke S" first="Shan" last="Wang-Gohrke">Shan Wang-Gohrke</name>
<affiliation><nlm:aff id="A22">Department of Obstetrics and Gynecology, University of Ulm, Ulm, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="John, Esther M" sort="John, Esther M" uniqKey="John E" first="Esther M." last="John">Esther M. John</name>
<affiliation><nlm:aff id="A23">Cancer Prevention Institute of California, Fremont, CA, USA and Stanford University School of Medicine and Stanford Cancer Institute, Stanford, CA, USA</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Miron, Alexander" sort="Miron, Alexander" uniqKey="Miron A" first="Alexander" last="Miron">Alexander Miron</name>
<affiliation><nlm:aff id="A24">Dana-Farber Cancer Institute, Boston, Massachusetts, USA</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Winqvist, Robert" sort="Winqvist, Robert" uniqKey="Winqvist R" first="Robert" last="Winqvist">Robert Winqvist</name>
<affiliation><nlm:aff id="A25">Laboratory of Cancer Genetics, Department of Clinical Genetics and Biocenter Oulu, University of Oulu, Oulu, Finland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Pylk S, Katri" sort="Pylk S, Katri" uniqKey="Pylk S K" first="Katri" last="Pylk S">Katri Pylk S</name>
<affiliation><nlm:aff id="A25">Laboratory of Cancer Genetics, Department of Clinical Genetics and Biocenter Oulu, University of Oulu, Oulu, Finland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Jukkola Vuorinen, Arja" sort="Jukkola Vuorinen, Arja" uniqKey="Jukkola Vuorinen A" first="Arja" last="Jukkola-Vuorinen">Arja Jukkola-Vuorinen</name>
<affiliation><nlm:aff id="A26">Department of Oncology, Oulu University Hospital, University of Oulu, Oulu, Finland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Grip, Mervi" sort="Grip, Mervi" uniqKey="Grip M" first="Mervi" last="Grip">Mervi Grip</name>
<affiliation><nlm:aff id="A27">Department of Surgery, Oulu University Hospital, University of Oulu, Oulu, Finland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Chenevix Trench, Georgia" sort="Chenevix Trench, Georgia" uniqKey="Chenevix Trench G" first="Georgia" last="Chenevix-Trench">Georgia Chenevix-Trench</name>
<affiliation><nlm:aff id="A28">Queensland Institute of Medical Research, Brisbane, Australia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Beesley, Jonathan" sort="Beesley, Jonathan" uniqKey="Beesley J" first="Jonathan" last="Beesley">Jonathan Beesley</name>
<affiliation><nlm:aff id="A28">Queensland Institute of Medical Research, Brisbane, Australia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Chen, Xiaoqing" sort="Chen, Xiaoqing" uniqKey="Chen X" first="Xiaoqing" last="Chen">Xiaoqing Chen</name>
<affiliation><nlm:aff id="A28">Queensland Institute of Medical Research, Brisbane, Australia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Menegaux, Florence" sort="Menegaux, Florence" uniqKey="Menegaux F" first="Florence" last="Menegaux">Florence Menegaux</name>
<affiliation><nlm:aff id="A2">Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer Team, Villejuif, France</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A3">University Paris-Sud, UMRS 1018, Villejuif, France</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Cordina Duverger, Emilie" sort="Cordina Duverger, Emilie" uniqKey="Cordina Duverger E" first="Emilie" last="Cordina-Duverger">Emilie Cordina-Duverger</name>
<affiliation><nlm:aff id="A2">Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer Team, Villejuif, France</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A3">University Paris-Sud, UMRS 1018, Villejuif, France</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Shen, Chen Yang" sort="Shen, Chen Yang" uniqKey="Shen C" first="Chen-Yang" last="Shen">Chen-Yang Shen</name>
<affiliation><nlm:aff id="A30">Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan; Taiwan Biobank, Taipei, Taiwan</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Yu, Jyh Cherng" sort="Yu, Jyh Cherng" uniqKey="Yu J" first="Jyh-Cherng" last="Yu">Jyh-Cherng Yu</name>
<affiliation><nlm:aff id="A31">Department of Surgery, Tri-Service General Hospital, Taipei, Taiwan</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Wu, Pei Ei" sort="Wu, Pei Ei" uniqKey="Wu P" first="Pei-Ei" last="Wu">Pei-Ei Wu</name>
<affiliation><nlm:aff id="A30">Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan; Taiwan Biobank, Taipei, Taiwan</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hou, Ming Feng" sort="Hou, Ming Feng" uniqKey="Hou M" first="Ming-Feng" last="Hou">Ming-Feng Hou</name>
<affiliation><nlm:aff id="A32">Cancer Center and Department of Surgery, Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Taiwan</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L." last="Andrulis">Irene L. Andrulis</name>
<affiliation><nlm:aff id="A33">Ontario Cancer Genetics Network, Cancer Care Ontario; Fred A. Litwin Center for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Selander, Teresa" sort="Selander, Teresa" uniqKey="Selander T" first="Teresa" last="Selander">Teresa Selander</name>
<affiliation><nlm:aff id="A34">Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Glendon, Gord" sort="Glendon, Gord" uniqKey="Glendon G" first="Gord" last="Glendon">Gord Glendon</name>
<affiliation><nlm:aff id="A34">Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Mulligan, Anna Marie" sort="Mulligan, Anna Marie" uniqKey="Mulligan A" first="Anna Marie" last="Mulligan">Anna Marie Mulligan</name>
<affiliation><nlm:aff id="A36">Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Anton Culver, Hoda" sort="Anton Culver, Hoda" uniqKey="Anton Culver H" first="Hoda" last="Anton-Culver">Hoda Anton-Culver</name>
<affiliation><nlm:aff id="A37">Department of Epidemiology, University of California Irvine, Irvine, California, USA</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ziogas, Argyrios" sort="Ziogas, Argyrios" uniqKey="Ziogas A" first="Argyrios" last="Ziogas">Argyrios Ziogas</name>
<affiliation><nlm:aff id="A37">Department of Epidemiology, University of California Irvine, Irvine, California, USA</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Muir, Kenneth R" sort="Muir, Kenneth R" uniqKey="Muir K" first="Kenneth R." last="Muir">Kenneth R. Muir</name>
<affiliation><nlm:aff id="A38">Health Sciences Research Institute, Warwick Medical School, Warwick University, Coventry, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lophatananon, Artitaya" sort="Lophatananon, Artitaya" uniqKey="Lophatananon A" first="Artitaya" last="Lophatananon">Artitaya Lophatananon</name>
<affiliation><nlm:aff id="A38">Health Sciences Research Institute, Warwick Medical School, Warwick University, Coventry, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rattanamongkongul, Suthee" sort="Rattanamongkongul, Suthee" uniqKey="Rattanamongkongul S" first="Suthee" last="Rattanamongkongul">Suthee Rattanamongkongul</name>
<affiliation><nlm:aff id="A39">Department of Preventive Medicine, Srinakhrainwirot University, Ongkharak, Nakhon Nayok, Thailand</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Puttawibul, Puttisak" sort="Puttawibul, Puttisak" uniqKey="Puttawibul P" first="Puttisak" last="Puttawibul">Puttisak Puttawibul</name>
<affiliation><nlm:aff id="A40">Department of Surgery, Medical School, Prince Songkla University, Songkla, Thailand</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Jones, Michael" sort="Jones, Michael" uniqKey="Jones M" first="Michael" last="Jones">Michael Jones</name>
<affiliation><nlm:aff id="A41">Section of Epidemiology, The Institute of Cancer Research, Sutton, Surrey, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Orr, Nicholas" sort="Orr, Nicholas" uniqKey="Orr N" first="Nicholas" last="Orr">Nicholas Orr</name>
<affiliation><nlm:aff id="A42">Breakthrough Breast Cancer Research Centre, Chester Beatty Laboratories, The Institute of Cancer Research, London, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ashworth, Alan" sort="Ashworth, Alan" uniqKey="Ashworth A" first="Alan" last="Ashworth">Alan Ashworth</name>
<affiliation><nlm:aff id="A42">Breakthrough Breast Cancer Research Centre, Chester Beatty Laboratories, The Institute of Cancer Research, London, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Swerdlow, Anthony" sort="Swerdlow, Anthony" uniqKey="Swerdlow A" first="Anthony" last="Swerdlow">Anthony Swerdlow</name>
<affiliation><nlm:aff id="A41">Section of Epidemiology, The Institute of Cancer Research, Sutton, Surrey, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Severi, Gianluca" sort="Severi, Gianluca" uniqKey="Severi G" first="Gianluca" last="Severi">Gianluca Severi</name>
<affiliation><nlm:aff id="A43">Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Baglietto, Laura" sort="Baglietto, Laura" uniqKey="Baglietto L" first="Laura" last="Baglietto">Laura Baglietto</name>
<affiliation><nlm:aff id="A43">Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Giles, Graham" sort="Giles, Graham" uniqKey="Giles G" first="Graham" last="Giles">Graham Giles</name>
<affiliation><nlm:aff id="A6">Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A43">Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Southey, Melissa" sort="Southey, Melissa" uniqKey="Southey M" first="Melissa" last="Southey">Melissa Southey</name>
<affiliation><nlm:aff id="A43">Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Marme, Federik" sort="Marme, Federik" uniqKey="Marme F" first="Federik" last="Marmé">Federik Marmé</name>
<affiliation><nlm:aff id="A44">National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A45">Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Schneeweiss, Andreas" sort="Schneeweiss, Andreas" uniqKey="Schneeweiss A" first="Andreas" last="Schneeweiss">Andreas Schneeweiss</name>
<affiliation><nlm:aff id="A44">National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A45">Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Sohn, Christof" sort="Sohn, Christof" uniqKey="Sohn C" first="Christof" last="Sohn">Christof Sohn</name>
<affiliation><nlm:aff id="A45">Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Burwinkel, Barbara" sort="Burwinkel, Barbara" uniqKey="Burwinkel B" first="Barbara" last="Burwinkel">Barbara Burwinkel</name>
<affiliation><nlm:aff id="A45">Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A46">Molecular Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Yesilyurt, Betul T" sort="Yesilyurt, Betul T" uniqKey="Yesilyurt B" first="Betul T." last="Yesilyurt">Betul T. Yesilyurt</name>
<affiliation><nlm:aff id="A1">Vesalius Research Center (VRC), VIB, KULeuven, Belgium</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Neven, Patrick" sort="Neven, Patrick" uniqKey="Neven P" first="Patrick" last="Neven">Patrick Neven</name>
<affiliation><nlm:aff id="A47">Multidisciplinary Breast Center, University Hospital Gasthuisberg, Leuven, Belgium</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Paridaens, Robert" sort="Paridaens, Robert" uniqKey="Paridaens R" first="Robert" last="Paridaens">Robert Paridaens</name>
<affiliation><nlm:aff id="A47">Multidisciplinary Breast Center, University Hospital Gasthuisberg, Leuven, Belgium</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Wildiers, Hans" sort="Wildiers, Hans" uniqKey="Wildiers H" first="Hans" last="Wildiers">Hans Wildiers</name>
<affiliation><nlm:aff id="A47">Multidisciplinary Breast Center, University Hospital Gasthuisberg, Leuven, Belgium</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Brenner, Hermann" sort="Brenner, Hermann" uniqKey="Brenner H" first="Hermann" last="Brenner">Hermann Brenner</name>
<affiliation><nlm:aff id="A48">Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Muller, Heiko" sort="Muller, Heiko" uniqKey="Muller H" first="Heiko" last="Müller">Heiko Müller</name>
<affiliation><nlm:aff id="A48">Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Arndt, Volker" sort="Arndt, Volker" uniqKey="Arndt V" first="Volker" last="Arndt">Volker Arndt</name>
<affiliation><nlm:aff id="A48">Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Stegmaier, Christa" sort="Stegmaier, Christa" uniqKey="Stegmaier C" first="Christa" last="Stegmaier">Christa Stegmaier</name>
<affiliation><nlm:aff id="A49">Saarland Cancer Registry, Saarbrücken, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Meindl, Alfons" sort="Meindl, Alfons" uniqKey="Meindl A" first="Alfons" last="Meindl">Alfons Meindl</name>
<affiliation><nlm:aff id="A50">Division of Gynaecology and Obstetrics, Technical University of Munich, Munich, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Schott, Sarah" sort="Schott, Sarah" uniqKey="Schott S" first="Sarah" last="Schott">Sarah Schott</name>
<affiliation><nlm:aff id="A51">Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Bartram, Claus R" sort="Bartram, Claus R" uniqKey="Bartram C" first="Claus R." last="Bartram">Claus R. Bartram</name>
<affiliation><nlm:aff id="A52">Institute of Human Genetics, University of Heidelberg, Heidelberg, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Schmutzler, Rita K" sort="Schmutzler, Rita K" uniqKey="Schmutzler R" first="Rita K." last="Schmutzler">Rita K. Schmutzler</name>
<affiliation><nlm:aff id="A53">Division of Molecular Gyneco-Oncology, Department of Gynaecology and Obstetrics, Center of Molecular Medicine Cologne (CMMC), University Hospital of Cologne, Cologne, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Cox, Angela" sort="Cox, Angela" uniqKey="Cox A" first="Angela" last="Cox">Angela Cox</name>
<affiliation><nlm:aff id="A54">Institute for Cancer Studies, Department of Oncology, University of Sheffield, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Brock, Ian W" sort="Brock, Ian W" uniqKey="Brock I" first="Ian W." last="Brock">Ian W. Brock</name>
<affiliation><nlm:aff id="A54">Institute for Cancer Studies, Department of Oncology, University of Sheffield, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Elliott, Graeme" sort="Elliott, Graeme" uniqKey="Elliott G" first="Graeme" last="Elliott">Graeme Elliott</name>
<affiliation><nlm:aff id="A55">Institute for Cancer Studies, Department of Oncology, University of Sheffield, UK; current address: University of Manchester, Manchester, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Cross, Simon S" sort="Cross, Simon S" uniqKey="Cross S" first="Simon S." last="Cross">Simon S. Cross</name>
<affiliation><nlm:aff id="A56">Academic Unit of Pathology, Department of Neuroscience, University of Sheffield, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Fasching, Peter A" sort="Fasching, Peter A" uniqKey="Fasching P" first="Peter A." last="Fasching">Peter A. Fasching</name>
<affiliation><nlm:aff id="A57">University Breast Center, Department of Gynecology and Obstetrics, University Hospital Erlangen, Erlangen, Germany; David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology, University of California at Los Angeles, CA, USA</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Schulz Wendtland, Ruediger" sort="Schulz Wendtland, Ruediger" uniqKey="Schulz Wendtland R" first="Ruediger" last="Schulz-Wendtland">Ruediger Schulz-Wendtland</name>
<affiliation><nlm:aff id="A58">Institute of Diagnostic Radiology, University Hospital Erlangen, Erlangen, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ekici, Arif B" sort="Ekici, Arif B" uniqKey="Ekici A" first="Arif B." last="Ekici">Arif B. Ekici</name>
<affiliation><nlm:aff id="A59">Institute of Human Genetics, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Beckmann, Matthias W" sort="Beckmann, Matthias W" uniqKey="Beckmann M" first="Matthias W." last="Beckmann">Matthias W. Beckmann</name>
<affiliation><nlm:aff id="A60">University Breast Center, Department of Gynecology and Obstetrics, University Hospital Erlangen, Erlangen, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Fletcher, Olivia" sort="Fletcher, Olivia" uniqKey="Fletcher O" first="Olivia" last="Fletcher">Olivia Fletcher</name>
<affiliation><nlm:aff id="A61">Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Johnson, Nichola" sort="Johnson, Nichola" uniqKey="Johnson N" first="Nichola" last="Johnson">Nichola Johnson</name>
<affiliation><nlm:aff id="A61">Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Silva, Isabel Dos Santos" sort="Silva, Isabel Dos Santos" uniqKey="Silva I" first="Isabel Dos Santos" last="Silva">Isabel Dos Santos Silva</name>
<affiliation><nlm:aff id="A62">London School of Hygiene and Tropical Medicine, London, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Peto, Julian" sort="Peto, Julian" uniqKey="Peto J" first="Julian" last="Peto">Julian Peto</name>
<affiliation><nlm:aff id="A62">London School of Hygiene and Tropical Medicine, London, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Nevanlinna, Heli" sort="Nevanlinna, Heli" uniqKey="Nevanlinna H" first="Heli" last="Nevanlinna">Heli Nevanlinna</name>
<affiliation><nlm:aff id="A63">Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Biomedicum Helsinki, Helsinki, Finland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Muranen, Taru A" sort="Muranen, Taru A" uniqKey="Muranen T" first="Taru A." last="Muranen">Taru A. Muranen</name>
<affiliation><nlm:aff id="A63">Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Biomedicum Helsinki, Helsinki, Finland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Aittom Ki, Kristiina" sort="Aittom Ki, Kristiina" uniqKey="Aittom Ki K" first="Kristiina" last="Aittom Ki">Kristiina Aittom Ki</name>
<affiliation><nlm:aff id="A64">Department of Clinical Genetics, Helsinki University Central Hospital, Helsinki, Finland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Blomqvist, Carl" sort="Blomqvist, Carl" uniqKey="Blomqvist C" first="Carl" last="Blomqvist">Carl Blomqvist</name>
<affiliation><nlm:aff id="A65">Department of Oncology, Helsinki University Central Hospital, Helsinki, Finland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Dork, Thilo" sort="Dork, Thilo" uniqKey="Dork T" first="Thilo" last="Dörk">Thilo Dörk</name>
<affiliation><nlm:aff id="A66">Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Schurmann, Peter" sort="Schurmann, Peter" uniqKey="Schurmann P" first="Peter" last="Schürmann">Peter Schürmann</name>
<affiliation><nlm:aff id="A66">Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Bremer, Michael" sort="Bremer, Michael" uniqKey="Bremer M" first="Michael" last="Bremer">Michael Bremer</name>
<affiliation><nlm:aff id="A67">Department of Radiation Oncology, Hannover Medical School, Hannover, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hillemanns, Peter" sort="Hillemanns, Peter" uniqKey="Hillemanns P" first="Peter" last="Hillemanns">Peter Hillemanns</name>
<affiliation><nlm:aff id="A66">Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Bogdanova, Natalia V" sort="Bogdanova, Natalia V" uniqKey="Bogdanova N" first="Natalia V." last="Bogdanova">Natalia V. Bogdanova</name>
<affiliation><nlm:aff id="A66">Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A67">Department of Radiation Oncology, Hannover Medical School, Hannover, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Antonenkova, Natalia N" sort="Antonenkova, Natalia N" uniqKey="Antonenkova N" first="Natalia N." last="Antonenkova">Natalia N. Antonenkova</name>
<affiliation><nlm:aff id="A68">N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rogov, Yuri I" sort="Rogov, Yuri I" uniqKey="Rogov Y" first="Yuri I." last="Rogov">Yuri I. Rogov</name>
<affiliation><nlm:aff id="A68">N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Karstens, Johann H" sort="Karstens, Johann H" uniqKey="Karstens J" first="Johann H." last="Karstens">Johann H. Karstens</name>
<affiliation><nlm:aff id="A66">Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Khusnutdinova, Elza" sort="Khusnutdinova, Elza" uniqKey="Khusnutdinova E" first="Elza" last="Khusnutdinova">Elza Khusnutdinova</name>
<affiliation><nlm:aff id="A69">Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Ufa, Russia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Bermisheva, Marina" sort="Bermisheva, Marina" uniqKey="Bermisheva M" first="Marina" last="Bermisheva">Marina Bermisheva</name>
<affiliation><nlm:aff id="A69">Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Ufa, Russia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Prokofieva, Darya" sort="Prokofieva, Darya" uniqKey="Prokofieva D" first="Darya" last="Prokofieva">Darya Prokofieva</name>
<affiliation><nlm:aff id="A69">Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Ufa, Russia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Gancev, Shamil" sort="Gancev, Shamil" uniqKey="Gancev S" first="Shamil" last="Gancev">Shamil Gancev</name>
<affiliation><nlm:aff id="A70">Bashkirian Medical University, Ufa, Russia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Jakubowska, Anna" sort="Jakubowska, Anna" uniqKey="Jakubowska A" first="Anna" last="Jakubowska">Anna Jakubowska</name>
<affiliation><nlm:aff id="A71">Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lubinski, Jan" sort="Lubinski, Jan" uniqKey="Lubinski J" first="Jan" last="Lubinski">Jan Lubinski</name>
<affiliation><nlm:aff id="A71">Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Jaworska, Katarzyna" sort="Jaworska, Katarzyna" uniqKey="Jaworska K" first="Katarzyna" last="Jaworska">Katarzyna Jaworska</name>
<affiliation><nlm:aff id="A71">Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A72">Postgraduate School of Molecular Medicine, Warsaw Medical University, Warsaw, Poland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Durda, Katarzyna" sort="Durda, Katarzyna" uniqKey="Durda K" first="Katarzyna" last="Durda">Katarzyna Durda</name>
<affiliation><nlm:aff id="A71">Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Nordestgaard, B Rge G" sort="Nordestgaard, B Rge G" uniqKey="Nordestgaard B" first="B Rge G." last="Nordestgaard">B Rge G. Nordestgaard</name>
<affiliation><nlm:aff id="A73">Copenhagen General Population Study and Department of Clinical Biochemistry, Herlev University Hospital, University of Copenhagen, Copenhagen, Denmark</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Bojesen, Stig E" sort="Bojesen, Stig E" uniqKey="Bojesen S" first="Stig E." last="Bojesen">Stig E. Bojesen</name>
<affiliation><nlm:aff id="A73">Copenhagen General Population Study and Department of Clinical Biochemistry, Herlev University Hospital, University of Copenhagen, Copenhagen, Denmark</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lanng, Charlotte" sort="Lanng, Charlotte" uniqKey="Lanng C" first="Charlotte" last="Lanng">Charlotte Lanng</name>
<affiliation><nlm:aff id="A74">Department of Breast Surgery, Herlev University Hospital, University of Copenhagen, Copenhagen, Denmark</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Mannermaa, Arto" sort="Mannermaa, Arto" uniqKey="Mannermaa A" first="Arto" last="Mannermaa">Arto Mannermaa</name>
<affiliation><nlm:aff id="A75">School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Biocenter Kuopio and Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kataja, Vesa" sort="Kataja, Vesa" uniqKey="Kataja V" first="Vesa" last="Kataja">Vesa Kataja</name>
<affiliation><nlm:aff id="A76">School of Medicine, Institute of Clinical Medicine, Oncology, University of Eastern Finland, Biocenter Kuopio and Department of Oncology, Kuopio University Hospital, Kuopio, Finland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kosma, Veli Matti" sort="Kosma, Veli Matti" uniqKey="Kosma V" first="Veli-Matti" last="Kosma">Veli-Matti Kosma</name>
<affiliation><nlm:aff id="A75">School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Biocenter Kuopio and Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hartikainen, Jaana M" sort="Hartikainen, Jaana M" uniqKey="Hartikainen J" first="Jaana M." last="Hartikainen">Jaana M. Hartikainen</name>
<affiliation><nlm:aff id="A75">School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Biocenter Kuopio and Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Radice, Paolo" sort="Radice, Paolo" uniqKey="Radice P" first="Paolo" last="Radice">Paolo Radice</name>
<affiliation><nlm:aff id="A77">Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predicted Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy and IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Peterlongo, Paolo" sort="Peterlongo, Paolo" uniqKey="Peterlongo P" first="Paolo" last="Peterlongo">Paolo Peterlongo</name>
<affiliation><nlm:aff id="A77">Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predicted Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy and IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Manoukian, Siranoush" sort="Manoukian, Siranoush" uniqKey="Manoukian S" first="Siranoush" last="Manoukian">Siranoush Manoukian</name>
<affiliation><nlm:aff id="A78">Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Bernard, Loris" sort="Bernard, Loris" uniqKey="Bernard L" first="Loris" last="Bernard">Loris Bernard</name>
<affiliation><nlm:aff id="A79">Department of Experimental Oncology, Istituto Europeo di Oncologia (IEO), Milan, Italy and Consortium for Genomics Technology (Cogentech) Milan, Italy</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Couch, Fergus J" sort="Couch, Fergus J" uniqKey="Couch F" first="Fergus J." last="Couch">Fergus J. Couch</name>
<affiliation><nlm:aff id="A80">Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Olson, Janet E" sort="Olson, Janet E" uniqKey="Olson J" first="Janet E." last="Olson">Janet E. Olson</name>
<affiliation><nlm:aff id="A81">Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Wang, Xianshu" sort="Wang, Xianshu" uniqKey="Wang X" first="Xianshu" last="Wang">Xianshu Wang</name>
<affiliation><nlm:aff id="A80">Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Fredericksen, Zachary" sort="Fredericksen, Zachary" uniqKey="Fredericksen Z" first="Zachary" last="Fredericksen">Zachary Fredericksen</name>
<affiliation><nlm:aff id="A81">Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Aln S, Grethe Grenaker" sort="Aln S, Grethe Grenaker" uniqKey="Aln S G" first="Grethe Grenaker" last="Aln S">Grethe Grenaker Aln S</name>
<affiliation><nlm:aff id="A82">Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo, Norway</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kristensen, Vessela" sort="Kristensen, Vessela" uniqKey="Kristensen V" first="Vessela" last="Kristensen">Vessela Kristensen</name>
<affiliation><nlm:aff id="A82">Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo, Norway</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A83">Faculty of Medicine (Faculty Division Ahus), UiO, Norway</nlm:aff>
</affiliation>
</author>
<author><name sortKey="B Rresen Dale, Anne Lise" sort="B Rresen Dale, Anne Lise" uniqKey="B Rresen Dale A" first="Anne-Lise" last="B Rresen-Dale">Anne-Lise B Rresen-Dale</name>
<affiliation><nlm:aff id="A82">Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo, Norway</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A83">Faculty of Medicine (Faculty Division Ahus), UiO, Norway</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Devilee, Peter" sort="Devilee, Peter" uniqKey="Devilee P" first="Peter" last="Devilee">Peter Devilee</name>
<affiliation><nlm:aff id="A84">Department of Human Genetics, and Department of Pathology, Leiden University Medical Centre, Leiden, The Netherlands</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Tollenaar, Robert A E M" sort="Tollenaar, Robert A E M" uniqKey="Tollenaar R" first="Robert A. E. M." last="Tollenaar">Robert A. E. M. Tollenaar</name>
<affiliation><nlm:aff id="A85">Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Seynaeve, Caroline M" sort="Seynaeve, Caroline M" uniqKey="Seynaeve C" first="Caroline M." last="Seynaeve">Caroline M. Seynaeve</name>
<affiliation><nlm:aff id="A86">Department of Medical Oncology, Rotterdam Family Cancer Clinic, Erasmus MC-Daniel den Hoed Cancer Center, Rotterdam, The Netherlands</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hooning, Maartje J" sort="Hooning, Maartje J" uniqKey="Hooning M" first="Maartje J." last="Hooning">Maartje J. Hooning</name>
<affiliation><nlm:aff id="A86">Department of Medical Oncology, Rotterdam Family Cancer Clinic, Erasmus MC-Daniel den Hoed Cancer Center, Rotterdam, The Netherlands</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Garcia Closas, Montserrat" sort="Garcia Closas, Montserrat" uniqKey="Garcia Closas M" first="Montserrat" last="García-Closas">Montserrat García-Closas</name>
<affiliation><nlm:aff id="A87">Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA; Division of Genetics and Epidemiology, Institute of Cancer Research and Breakthrough Breast Cancer Research Centre, London, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J." last="Chanock">Stephen J. Chanock</name>
<affiliation><nlm:aff id="A88">Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lissowska, Jolanta" sort="Lissowska, Jolanta" uniqKey="Lissowska J" first="Jolanta" last="Lissowska">Jolanta Lissowska</name>
<affiliation><nlm:aff id="A89">Department of Cancer Epidemiology and Prevention, M. Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Sherman, Mark E" sort="Sherman, Mark E" uniqKey="Sherman M" first="Mark E." last="Sherman">Mark E. Sherman</name>
<affiliation><nlm:aff id="A88">Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hall, Per" sort="Hall, Per" uniqKey="Hall P" first="Per" last="Hall">Per Hall</name>
<affiliation><nlm:aff id="A90">Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Liu, Jianjun" sort="Liu, Jianjun" uniqKey="Liu J" first="Jianjun" last="Liu">Jianjun Liu</name>
<affiliation><nlm:aff id="A90">Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Czene, Kamila" sort="Czene, Kamila" uniqKey="Czene K" first="Kamila" last="Czene">Kamila Czene</name>
<affiliation><nlm:aff id="A90">Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kang, Daehee" sort="Kang, Daehee" uniqKey="Kang D" first="Daehee" last="Kang">Daehee Kang</name>
<affiliation><nlm:aff id="A91">Seoul National University College of Medicine, Seoul, Korea</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Yoo, Keun Young" sort="Yoo, Keun Young" uniqKey="Yoo K" first="Keun-Young" last="Yoo">Keun-Young Yoo</name>
<affiliation><nlm:aff id="A91">Seoul National University College of Medicine, Seoul, Korea</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Noh, Dong Young" sort="Noh, Dong Young" uniqKey="Noh D" first="Dong-Young" last="Noh">Dong-Young Noh</name>
<affiliation><nlm:aff id="A91">Seoul National University College of Medicine, Seoul, Korea</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lindblom, Annika" sort="Lindblom, Annika" uniqKey="Lindblom A" first="Annika" last="Lindblom">Annika Lindblom</name>
<affiliation><nlm:aff id="A92">Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Margolin, Sara" sort="Margolin, Sara" uniqKey="Margolin S" first="Sara" last="Margolin">Sara Margolin</name>
<affiliation><nlm:aff id="A93">Department of Oncology Pathology, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Dunning, Alison M" sort="Dunning, Alison M" uniqKey="Dunning A" first="Alison M." last="Dunning">Alison M. Dunning</name>
<affiliation><nlm:aff id="A94">Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Pharoah, Paul D P" sort="Pharoah, Paul D P" uniqKey="Pharoah P" first="Paul D. P." last="Pharoah">Paul D. P. Pharoah</name>
<affiliation><nlm:aff id="A5">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A94">Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F." last="Easton">Douglas F. Easton</name>
<affiliation><nlm:aff id="A5">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A94">Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Guenel, Pascal" sort="Guenel, Pascal" uniqKey="Guenel P" first="Pascal" last="Guénel">Pascal Guénel</name>
<affiliation><nlm:aff id="A2">Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer Team, Villejuif, France</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A3">University Paris-Sud, UMRS 1018, Villejuif, France</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Brauch, Hiltrud" sort="Brauch, Hiltrud" uniqKey="Brauch H" first="Hiltrud" last="Brauch">Hiltrud Brauch</name>
<affiliation><nlm:aff id="A4">Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, and University Tübingen, Germany</nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">22461340</idno>
<idno type="pmc">3370081</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370081</idno>
<idno type="RBID">PMC:3370081</idno>
<idno type="doi">10.1002/humu.22089</idno>
<date when="2012">2012</date>
<idno type="wicri:Area/Pmc/Corpus">002108</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002108</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">11q13 is a Susceptibility Locus for Hormone Receptor Positive Breast Cancer<xref ref-type="fn" rid="FN3">†</xref>
</title>
<author><name sortKey="Lambrechts, Diether" sort="Lambrechts, Diether" uniqKey="Lambrechts D" first="Diether" last="Lambrechts">Diether Lambrechts</name>
<affiliation><nlm:aff id="A1">Vesalius Research Center (VRC), VIB, KULeuven, Belgium</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Truong, Therese" sort="Truong, Therese" uniqKey="Truong T" first="Therese" last="Truong">Therese Truong</name>
<affiliation><nlm:aff id="A2">Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer Team, Villejuif, France</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A3">University Paris-Sud, UMRS 1018, Villejuif, France</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Justenhoven, Christina" sort="Justenhoven, Christina" uniqKey="Justenhoven C" first="Christina" last="Justenhoven">Christina Justenhoven</name>
<affiliation><nlm:aff id="A4">Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, and University Tübingen, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Humphreys, Manjeet K" sort="Humphreys, Manjeet K" uniqKey="Humphreys M" first="Manjeet K." last="Humphreys">Manjeet K. Humphreys</name>
<affiliation><nlm:aff id="A5">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Wang, Jean" sort="Wang, Jean" uniqKey="Wang J" first="Jean" last="Wang">Jean Wang</name>
<affiliation><nlm:aff id="A5">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hopper, John L" sort="Hopper, John L" uniqKey="Hopper J" first="John L." last="Hopper">John L. Hopper</name>
<affiliation><nlm:aff id="A6">Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Dite, Gillian S" sort="Dite, Gillian S" uniqKey="Dite G" first="Gillian S." last="Dite">Gillian S. Dite</name>
<affiliation><nlm:aff id="A6">Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Apicella, Carmel" sort="Apicella, Carmel" uniqKey="Apicella C" first="Carmel" last="Apicella">Carmel Apicella</name>
<affiliation><nlm:aff id="A6">Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Southey, Melissa C" sort="Southey, Melissa C" uniqKey="Southey M" first="Melissa C." last="Southey">Melissa C. Southey</name>
<affiliation><nlm:aff id="A7">Department of Pathology, The University of Melbourne, Melbourne, Australia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Schmidt, Marjanka K" sort="Schmidt, Marjanka K" uniqKey="Schmidt M" first="Marjanka K." last="Schmidt">Marjanka K. Schmidt</name>
<affiliation><nlm:aff id="A8">Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Broeks, Annegien" sort="Broeks, Annegien" uniqKey="Broeks A" first="Annegien" last="Broeks">Annegien Broeks</name>
<affiliation><nlm:aff id="A8">Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Cornelissen, Sten" sort="Cornelissen, Sten" uniqKey="Cornelissen S" first="Sten" last="Cornelissen">Sten Cornelissen</name>
<affiliation><nlm:aff id="A8">Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Van Hien, Richard" sort="Van Hien, Richard" uniqKey="Van Hien R" first="Richard" last="Van Hien">Richard Van Hien</name>
<affiliation><nlm:aff id="A8">Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Sawyer, Elinor" sort="Sawyer, Elinor" uniqKey="Sawyer E" first="Elinor" last="Sawyer">Elinor Sawyer</name>
<affiliation><nlm:aff id="A9">Division of Cancer Studies, NIHR Comprehensive Biomedical Research Centre, Guy's & St. Thomas' NHS Foundation Trust in partnership with King's College London, London, United Kingdom</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Tomlinson, Ian" sort="Tomlinson, Ian" uniqKey="Tomlinson I" first="Ian" last="Tomlinson">Ian Tomlinson</name>
<affiliation><nlm:aff id="A10">Welcome Trust Centre for Human Genetics and Oxford Biomedical Research Centre, University of Oxford, United Kingdom</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kerin, Michael" sort="Kerin, Michael" uniqKey="Kerin M" first="Michael" last="Kerin">Michael Kerin</name>
<affiliation><nlm:aff id="A11">Clinical Science Institute. University Hospital Galway, Galway, Ireland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Miller, Nicola" sort="Miller, Nicola" uniqKey="Miller N" first="Nicola" last="Miller">Nicola Miller</name>
<affiliation><nlm:aff id="A11">Clinical Science Institute. University Hospital Galway, Galway, Ireland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Milne, Roger L" sort="Milne, Roger L" uniqKey="Milne R" first="Roger L." last="Milne">Roger L. Milne</name>
<affiliation><nlm:aff id="A12">Genetic and Molecular Epidemiology Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Zamora, M Pilar" sort="Zamora, M Pilar" uniqKey="Zamora M" first="M. Pilar" last="Zamora">M. Pilar Zamora</name>
<affiliation><nlm:aff id="A13">Servicio de Oncología Médica, Hospital Universitario La Paz, Madrid, Spain</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Arias Perez, Jose Ignacio" sort="Arias Perez, Jose Ignacio" uniqKey="Arias Perez J" first="José Ignacio" last="Arias Pérez">José Ignacio Arias Pérez</name>
<affiliation><nlm:aff id="A14">Servicio de Cirugía General y Especialidades, Hospital Monte Naranco, Oviedo, Spain</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Benitez, Javier" sort="Benitez, Javier" uniqKey="Benitez J" first="Javier" last="Benítez">Javier Benítez</name>
<affiliation><nlm:aff id="A15">Human Genetics Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hamann, Ute" sort="Hamann, Ute" uniqKey="Hamann U" first="Ute" last="Hamann">Ute Hamann</name>
<affiliation><nlm:aff id="A16">Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ko, Yon Dschun" sort="Ko, Yon Dschun" uniqKey="Ko Y" first="Yon-Dschun" last="Ko">Yon-Dschun Ko</name>
<affiliation><nlm:aff id="A17">Department of Internal Medicine, Evangelische Kliniken Bonn gGmbH, Johanniter Krankenhaus, Bonn, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Bruning, Thomas" sort="Bruning, Thomas" uniqKey="Bruning T" first="Thomas" last="Brüning">Thomas Brüning</name>
<affiliation><nlm:aff id="A18">Institute for Prevention and Occupational Medicine of the German Social Accident Insurance (IPA), Bochum, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Chang Claude, Jenny" sort="Chang Claude, Jenny" uniqKey="Chang Claude J" first="Jenny" last="Chang-Claude">Jenny Chang-Claude</name>
<affiliation><nlm:aff id="A20">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Eilber, Ursel" sort="Eilber, Ursel" uniqKey="Eilber U" first="Ursel" last="Eilber">Ursel Eilber</name>
<affiliation><nlm:aff id="A20">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hein, Rebecca" sort="Hein, Rebecca" uniqKey="Hein R" first="Rebecca" last="Hein">Rebecca Hein</name>
<affiliation><nlm:aff id="A20">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Nickels, Stefan" sort="Nickels, Stefan" uniqKey="Nickels S" first="Stefan" last="Nickels">Stefan Nickels</name>
<affiliation><nlm:aff id="A20">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Flesch Janys, Dieter" sort="Flesch Janys, Dieter" uniqKey="Flesch Janys D" first="Dieter" last="Flesch-Janys">Dieter Flesch-Janys</name>
<affiliation><nlm:aff id="A21">Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Wang Gohrke, Shan" sort="Wang Gohrke, Shan" uniqKey="Wang Gohrke S" first="Shan" last="Wang-Gohrke">Shan Wang-Gohrke</name>
<affiliation><nlm:aff id="A22">Department of Obstetrics and Gynecology, University of Ulm, Ulm, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="John, Esther M" sort="John, Esther M" uniqKey="John E" first="Esther M." last="John">Esther M. John</name>
<affiliation><nlm:aff id="A23">Cancer Prevention Institute of California, Fremont, CA, USA and Stanford University School of Medicine and Stanford Cancer Institute, Stanford, CA, USA</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Miron, Alexander" sort="Miron, Alexander" uniqKey="Miron A" first="Alexander" last="Miron">Alexander Miron</name>
<affiliation><nlm:aff id="A24">Dana-Farber Cancer Institute, Boston, Massachusetts, USA</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Winqvist, Robert" sort="Winqvist, Robert" uniqKey="Winqvist R" first="Robert" last="Winqvist">Robert Winqvist</name>
<affiliation><nlm:aff id="A25">Laboratory of Cancer Genetics, Department of Clinical Genetics and Biocenter Oulu, University of Oulu, Oulu, Finland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Pylk S, Katri" sort="Pylk S, Katri" uniqKey="Pylk S K" first="Katri" last="Pylk S">Katri Pylk S</name>
<affiliation><nlm:aff id="A25">Laboratory of Cancer Genetics, Department of Clinical Genetics and Biocenter Oulu, University of Oulu, Oulu, Finland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Jukkola Vuorinen, Arja" sort="Jukkola Vuorinen, Arja" uniqKey="Jukkola Vuorinen A" first="Arja" last="Jukkola-Vuorinen">Arja Jukkola-Vuorinen</name>
<affiliation><nlm:aff id="A26">Department of Oncology, Oulu University Hospital, University of Oulu, Oulu, Finland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Grip, Mervi" sort="Grip, Mervi" uniqKey="Grip M" first="Mervi" last="Grip">Mervi Grip</name>
<affiliation><nlm:aff id="A27">Department of Surgery, Oulu University Hospital, University of Oulu, Oulu, Finland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Chenevix Trench, Georgia" sort="Chenevix Trench, Georgia" uniqKey="Chenevix Trench G" first="Georgia" last="Chenevix-Trench">Georgia Chenevix-Trench</name>
<affiliation><nlm:aff id="A28">Queensland Institute of Medical Research, Brisbane, Australia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Beesley, Jonathan" sort="Beesley, Jonathan" uniqKey="Beesley J" first="Jonathan" last="Beesley">Jonathan Beesley</name>
<affiliation><nlm:aff id="A28">Queensland Institute of Medical Research, Brisbane, Australia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Chen, Xiaoqing" sort="Chen, Xiaoqing" uniqKey="Chen X" first="Xiaoqing" last="Chen">Xiaoqing Chen</name>
<affiliation><nlm:aff id="A28">Queensland Institute of Medical Research, Brisbane, Australia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Menegaux, Florence" sort="Menegaux, Florence" uniqKey="Menegaux F" first="Florence" last="Menegaux">Florence Menegaux</name>
<affiliation><nlm:aff id="A2">Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer Team, Villejuif, France</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A3">University Paris-Sud, UMRS 1018, Villejuif, France</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Cordina Duverger, Emilie" sort="Cordina Duverger, Emilie" uniqKey="Cordina Duverger E" first="Emilie" last="Cordina-Duverger">Emilie Cordina-Duverger</name>
<affiliation><nlm:aff id="A2">Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer Team, Villejuif, France</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A3">University Paris-Sud, UMRS 1018, Villejuif, France</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Shen, Chen Yang" sort="Shen, Chen Yang" uniqKey="Shen C" first="Chen-Yang" last="Shen">Chen-Yang Shen</name>
<affiliation><nlm:aff id="A30">Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan; Taiwan Biobank, Taipei, Taiwan</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Yu, Jyh Cherng" sort="Yu, Jyh Cherng" uniqKey="Yu J" first="Jyh-Cherng" last="Yu">Jyh-Cherng Yu</name>
<affiliation><nlm:aff id="A31">Department of Surgery, Tri-Service General Hospital, Taipei, Taiwan</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Wu, Pei Ei" sort="Wu, Pei Ei" uniqKey="Wu P" first="Pei-Ei" last="Wu">Pei-Ei Wu</name>
<affiliation><nlm:aff id="A30">Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan; Taiwan Biobank, Taipei, Taiwan</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hou, Ming Feng" sort="Hou, Ming Feng" uniqKey="Hou M" first="Ming-Feng" last="Hou">Ming-Feng Hou</name>
<affiliation><nlm:aff id="A32">Cancer Center and Department of Surgery, Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Taiwan</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L." last="Andrulis">Irene L. Andrulis</name>
<affiliation><nlm:aff id="A33">Ontario Cancer Genetics Network, Cancer Care Ontario; Fred A. Litwin Center for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Selander, Teresa" sort="Selander, Teresa" uniqKey="Selander T" first="Teresa" last="Selander">Teresa Selander</name>
<affiliation><nlm:aff id="A34">Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Glendon, Gord" sort="Glendon, Gord" uniqKey="Glendon G" first="Gord" last="Glendon">Gord Glendon</name>
<affiliation><nlm:aff id="A34">Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Mulligan, Anna Marie" sort="Mulligan, Anna Marie" uniqKey="Mulligan A" first="Anna Marie" last="Mulligan">Anna Marie Mulligan</name>
<affiliation><nlm:aff id="A36">Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Anton Culver, Hoda" sort="Anton Culver, Hoda" uniqKey="Anton Culver H" first="Hoda" last="Anton-Culver">Hoda Anton-Culver</name>
<affiliation><nlm:aff id="A37">Department of Epidemiology, University of California Irvine, Irvine, California, USA</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ziogas, Argyrios" sort="Ziogas, Argyrios" uniqKey="Ziogas A" first="Argyrios" last="Ziogas">Argyrios Ziogas</name>
<affiliation><nlm:aff id="A37">Department of Epidemiology, University of California Irvine, Irvine, California, USA</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Muir, Kenneth R" sort="Muir, Kenneth R" uniqKey="Muir K" first="Kenneth R." last="Muir">Kenneth R. Muir</name>
<affiliation><nlm:aff id="A38">Health Sciences Research Institute, Warwick Medical School, Warwick University, Coventry, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lophatananon, Artitaya" sort="Lophatananon, Artitaya" uniqKey="Lophatananon A" first="Artitaya" last="Lophatananon">Artitaya Lophatananon</name>
<affiliation><nlm:aff id="A38">Health Sciences Research Institute, Warwick Medical School, Warwick University, Coventry, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rattanamongkongul, Suthee" sort="Rattanamongkongul, Suthee" uniqKey="Rattanamongkongul S" first="Suthee" last="Rattanamongkongul">Suthee Rattanamongkongul</name>
<affiliation><nlm:aff id="A39">Department of Preventive Medicine, Srinakhrainwirot University, Ongkharak, Nakhon Nayok, Thailand</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Puttawibul, Puttisak" sort="Puttawibul, Puttisak" uniqKey="Puttawibul P" first="Puttisak" last="Puttawibul">Puttisak Puttawibul</name>
<affiliation><nlm:aff id="A40">Department of Surgery, Medical School, Prince Songkla University, Songkla, Thailand</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Jones, Michael" sort="Jones, Michael" uniqKey="Jones M" first="Michael" last="Jones">Michael Jones</name>
<affiliation><nlm:aff id="A41">Section of Epidemiology, The Institute of Cancer Research, Sutton, Surrey, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Orr, Nicholas" sort="Orr, Nicholas" uniqKey="Orr N" first="Nicholas" last="Orr">Nicholas Orr</name>
<affiliation><nlm:aff id="A42">Breakthrough Breast Cancer Research Centre, Chester Beatty Laboratories, The Institute of Cancer Research, London, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ashworth, Alan" sort="Ashworth, Alan" uniqKey="Ashworth A" first="Alan" last="Ashworth">Alan Ashworth</name>
<affiliation><nlm:aff id="A42">Breakthrough Breast Cancer Research Centre, Chester Beatty Laboratories, The Institute of Cancer Research, London, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Swerdlow, Anthony" sort="Swerdlow, Anthony" uniqKey="Swerdlow A" first="Anthony" last="Swerdlow">Anthony Swerdlow</name>
<affiliation><nlm:aff id="A41">Section of Epidemiology, The Institute of Cancer Research, Sutton, Surrey, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Severi, Gianluca" sort="Severi, Gianluca" uniqKey="Severi G" first="Gianluca" last="Severi">Gianluca Severi</name>
<affiliation><nlm:aff id="A43">Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Baglietto, Laura" sort="Baglietto, Laura" uniqKey="Baglietto L" first="Laura" last="Baglietto">Laura Baglietto</name>
<affiliation><nlm:aff id="A43">Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Giles, Graham" sort="Giles, Graham" uniqKey="Giles G" first="Graham" last="Giles">Graham Giles</name>
<affiliation><nlm:aff id="A6">Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A43">Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Southey, Melissa" sort="Southey, Melissa" uniqKey="Southey M" first="Melissa" last="Southey">Melissa Southey</name>
<affiliation><nlm:aff id="A43">Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Marme, Federik" sort="Marme, Federik" uniqKey="Marme F" first="Federik" last="Marmé">Federik Marmé</name>
<affiliation><nlm:aff id="A44">National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A45">Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Schneeweiss, Andreas" sort="Schneeweiss, Andreas" uniqKey="Schneeweiss A" first="Andreas" last="Schneeweiss">Andreas Schneeweiss</name>
<affiliation><nlm:aff id="A44">National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A45">Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Sohn, Christof" sort="Sohn, Christof" uniqKey="Sohn C" first="Christof" last="Sohn">Christof Sohn</name>
<affiliation><nlm:aff id="A45">Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Burwinkel, Barbara" sort="Burwinkel, Barbara" uniqKey="Burwinkel B" first="Barbara" last="Burwinkel">Barbara Burwinkel</name>
<affiliation><nlm:aff id="A45">Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A46">Molecular Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Yesilyurt, Betul T" sort="Yesilyurt, Betul T" uniqKey="Yesilyurt B" first="Betul T." last="Yesilyurt">Betul T. Yesilyurt</name>
<affiliation><nlm:aff id="A1">Vesalius Research Center (VRC), VIB, KULeuven, Belgium</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Neven, Patrick" sort="Neven, Patrick" uniqKey="Neven P" first="Patrick" last="Neven">Patrick Neven</name>
<affiliation><nlm:aff id="A47">Multidisciplinary Breast Center, University Hospital Gasthuisberg, Leuven, Belgium</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Paridaens, Robert" sort="Paridaens, Robert" uniqKey="Paridaens R" first="Robert" last="Paridaens">Robert Paridaens</name>
<affiliation><nlm:aff id="A47">Multidisciplinary Breast Center, University Hospital Gasthuisberg, Leuven, Belgium</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Wildiers, Hans" sort="Wildiers, Hans" uniqKey="Wildiers H" first="Hans" last="Wildiers">Hans Wildiers</name>
<affiliation><nlm:aff id="A47">Multidisciplinary Breast Center, University Hospital Gasthuisberg, Leuven, Belgium</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Brenner, Hermann" sort="Brenner, Hermann" uniqKey="Brenner H" first="Hermann" last="Brenner">Hermann Brenner</name>
<affiliation><nlm:aff id="A48">Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Muller, Heiko" sort="Muller, Heiko" uniqKey="Muller H" first="Heiko" last="Müller">Heiko Müller</name>
<affiliation><nlm:aff id="A48">Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Arndt, Volker" sort="Arndt, Volker" uniqKey="Arndt V" first="Volker" last="Arndt">Volker Arndt</name>
<affiliation><nlm:aff id="A48">Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Stegmaier, Christa" sort="Stegmaier, Christa" uniqKey="Stegmaier C" first="Christa" last="Stegmaier">Christa Stegmaier</name>
<affiliation><nlm:aff id="A49">Saarland Cancer Registry, Saarbrücken, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Meindl, Alfons" sort="Meindl, Alfons" uniqKey="Meindl A" first="Alfons" last="Meindl">Alfons Meindl</name>
<affiliation><nlm:aff id="A50">Division of Gynaecology and Obstetrics, Technical University of Munich, Munich, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Schott, Sarah" sort="Schott, Sarah" uniqKey="Schott S" first="Sarah" last="Schott">Sarah Schott</name>
<affiliation><nlm:aff id="A51">Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Bartram, Claus R" sort="Bartram, Claus R" uniqKey="Bartram C" first="Claus R." last="Bartram">Claus R. Bartram</name>
<affiliation><nlm:aff id="A52">Institute of Human Genetics, University of Heidelberg, Heidelberg, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Schmutzler, Rita K" sort="Schmutzler, Rita K" uniqKey="Schmutzler R" first="Rita K." last="Schmutzler">Rita K. Schmutzler</name>
<affiliation><nlm:aff id="A53">Division of Molecular Gyneco-Oncology, Department of Gynaecology and Obstetrics, Center of Molecular Medicine Cologne (CMMC), University Hospital of Cologne, Cologne, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Cox, Angela" sort="Cox, Angela" uniqKey="Cox A" first="Angela" last="Cox">Angela Cox</name>
<affiliation><nlm:aff id="A54">Institute for Cancer Studies, Department of Oncology, University of Sheffield, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Brock, Ian W" sort="Brock, Ian W" uniqKey="Brock I" first="Ian W." last="Brock">Ian W. Brock</name>
<affiliation><nlm:aff id="A54">Institute for Cancer Studies, Department of Oncology, University of Sheffield, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Elliott, Graeme" sort="Elliott, Graeme" uniqKey="Elliott G" first="Graeme" last="Elliott">Graeme Elliott</name>
<affiliation><nlm:aff id="A55">Institute for Cancer Studies, Department of Oncology, University of Sheffield, UK; current address: University of Manchester, Manchester, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Cross, Simon S" sort="Cross, Simon S" uniqKey="Cross S" first="Simon S." last="Cross">Simon S. Cross</name>
<affiliation><nlm:aff id="A56">Academic Unit of Pathology, Department of Neuroscience, University of Sheffield, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Fasching, Peter A" sort="Fasching, Peter A" uniqKey="Fasching P" first="Peter A." last="Fasching">Peter A. Fasching</name>
<affiliation><nlm:aff id="A57">University Breast Center, Department of Gynecology and Obstetrics, University Hospital Erlangen, Erlangen, Germany; David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology, University of California at Los Angeles, CA, USA</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Schulz Wendtland, Ruediger" sort="Schulz Wendtland, Ruediger" uniqKey="Schulz Wendtland R" first="Ruediger" last="Schulz-Wendtland">Ruediger Schulz-Wendtland</name>
<affiliation><nlm:aff id="A58">Institute of Diagnostic Radiology, University Hospital Erlangen, Erlangen, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ekici, Arif B" sort="Ekici, Arif B" uniqKey="Ekici A" first="Arif B." last="Ekici">Arif B. Ekici</name>
<affiliation><nlm:aff id="A59">Institute of Human Genetics, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Beckmann, Matthias W" sort="Beckmann, Matthias W" uniqKey="Beckmann M" first="Matthias W." last="Beckmann">Matthias W. Beckmann</name>
<affiliation><nlm:aff id="A60">University Breast Center, Department of Gynecology and Obstetrics, University Hospital Erlangen, Erlangen, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Fletcher, Olivia" sort="Fletcher, Olivia" uniqKey="Fletcher O" first="Olivia" last="Fletcher">Olivia Fletcher</name>
<affiliation><nlm:aff id="A61">Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Johnson, Nichola" sort="Johnson, Nichola" uniqKey="Johnson N" first="Nichola" last="Johnson">Nichola Johnson</name>
<affiliation><nlm:aff id="A61">Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Silva, Isabel Dos Santos" sort="Silva, Isabel Dos Santos" uniqKey="Silva I" first="Isabel Dos Santos" last="Silva">Isabel Dos Santos Silva</name>
<affiliation><nlm:aff id="A62">London School of Hygiene and Tropical Medicine, London, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Peto, Julian" sort="Peto, Julian" uniqKey="Peto J" first="Julian" last="Peto">Julian Peto</name>
<affiliation><nlm:aff id="A62">London School of Hygiene and Tropical Medicine, London, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Nevanlinna, Heli" sort="Nevanlinna, Heli" uniqKey="Nevanlinna H" first="Heli" last="Nevanlinna">Heli Nevanlinna</name>
<affiliation><nlm:aff id="A63">Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Biomedicum Helsinki, Helsinki, Finland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Muranen, Taru A" sort="Muranen, Taru A" uniqKey="Muranen T" first="Taru A." last="Muranen">Taru A. Muranen</name>
<affiliation><nlm:aff id="A63">Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Biomedicum Helsinki, Helsinki, Finland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Aittom Ki, Kristiina" sort="Aittom Ki, Kristiina" uniqKey="Aittom Ki K" first="Kristiina" last="Aittom Ki">Kristiina Aittom Ki</name>
<affiliation><nlm:aff id="A64">Department of Clinical Genetics, Helsinki University Central Hospital, Helsinki, Finland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Blomqvist, Carl" sort="Blomqvist, Carl" uniqKey="Blomqvist C" first="Carl" last="Blomqvist">Carl Blomqvist</name>
<affiliation><nlm:aff id="A65">Department of Oncology, Helsinki University Central Hospital, Helsinki, Finland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Dork, Thilo" sort="Dork, Thilo" uniqKey="Dork T" first="Thilo" last="Dörk">Thilo Dörk</name>
<affiliation><nlm:aff id="A66">Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Schurmann, Peter" sort="Schurmann, Peter" uniqKey="Schurmann P" first="Peter" last="Schürmann">Peter Schürmann</name>
<affiliation><nlm:aff id="A66">Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Bremer, Michael" sort="Bremer, Michael" uniqKey="Bremer M" first="Michael" last="Bremer">Michael Bremer</name>
<affiliation><nlm:aff id="A67">Department of Radiation Oncology, Hannover Medical School, Hannover, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hillemanns, Peter" sort="Hillemanns, Peter" uniqKey="Hillemanns P" first="Peter" last="Hillemanns">Peter Hillemanns</name>
<affiliation><nlm:aff id="A66">Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Bogdanova, Natalia V" sort="Bogdanova, Natalia V" uniqKey="Bogdanova N" first="Natalia V." last="Bogdanova">Natalia V. Bogdanova</name>
<affiliation><nlm:aff id="A66">Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A67">Department of Radiation Oncology, Hannover Medical School, Hannover, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Antonenkova, Natalia N" sort="Antonenkova, Natalia N" uniqKey="Antonenkova N" first="Natalia N." last="Antonenkova">Natalia N. Antonenkova</name>
<affiliation><nlm:aff id="A68">N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rogov, Yuri I" sort="Rogov, Yuri I" uniqKey="Rogov Y" first="Yuri I." last="Rogov">Yuri I. Rogov</name>
<affiliation><nlm:aff id="A68">N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Karstens, Johann H" sort="Karstens, Johann H" uniqKey="Karstens J" first="Johann H." last="Karstens">Johann H. Karstens</name>
<affiliation><nlm:aff id="A66">Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Khusnutdinova, Elza" sort="Khusnutdinova, Elza" uniqKey="Khusnutdinova E" first="Elza" last="Khusnutdinova">Elza Khusnutdinova</name>
<affiliation><nlm:aff id="A69">Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Ufa, Russia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Bermisheva, Marina" sort="Bermisheva, Marina" uniqKey="Bermisheva M" first="Marina" last="Bermisheva">Marina Bermisheva</name>
<affiliation><nlm:aff id="A69">Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Ufa, Russia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Prokofieva, Darya" sort="Prokofieva, Darya" uniqKey="Prokofieva D" first="Darya" last="Prokofieva">Darya Prokofieva</name>
<affiliation><nlm:aff id="A69">Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Ufa, Russia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Gancev, Shamil" sort="Gancev, Shamil" uniqKey="Gancev S" first="Shamil" last="Gancev">Shamil Gancev</name>
<affiliation><nlm:aff id="A70">Bashkirian Medical University, Ufa, Russia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Jakubowska, Anna" sort="Jakubowska, Anna" uniqKey="Jakubowska A" first="Anna" last="Jakubowska">Anna Jakubowska</name>
<affiliation><nlm:aff id="A71">Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lubinski, Jan" sort="Lubinski, Jan" uniqKey="Lubinski J" first="Jan" last="Lubinski">Jan Lubinski</name>
<affiliation><nlm:aff id="A71">Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Jaworska, Katarzyna" sort="Jaworska, Katarzyna" uniqKey="Jaworska K" first="Katarzyna" last="Jaworska">Katarzyna Jaworska</name>
<affiliation><nlm:aff id="A71">Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A72">Postgraduate School of Molecular Medicine, Warsaw Medical University, Warsaw, Poland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Durda, Katarzyna" sort="Durda, Katarzyna" uniqKey="Durda K" first="Katarzyna" last="Durda">Katarzyna Durda</name>
<affiliation><nlm:aff id="A71">Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Nordestgaard, B Rge G" sort="Nordestgaard, B Rge G" uniqKey="Nordestgaard B" first="B Rge G." last="Nordestgaard">B Rge G. Nordestgaard</name>
<affiliation><nlm:aff id="A73">Copenhagen General Population Study and Department of Clinical Biochemistry, Herlev University Hospital, University of Copenhagen, Copenhagen, Denmark</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Bojesen, Stig E" sort="Bojesen, Stig E" uniqKey="Bojesen S" first="Stig E." last="Bojesen">Stig E. Bojesen</name>
<affiliation><nlm:aff id="A73">Copenhagen General Population Study and Department of Clinical Biochemistry, Herlev University Hospital, University of Copenhagen, Copenhagen, Denmark</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lanng, Charlotte" sort="Lanng, Charlotte" uniqKey="Lanng C" first="Charlotte" last="Lanng">Charlotte Lanng</name>
<affiliation><nlm:aff id="A74">Department of Breast Surgery, Herlev University Hospital, University of Copenhagen, Copenhagen, Denmark</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Mannermaa, Arto" sort="Mannermaa, Arto" uniqKey="Mannermaa A" first="Arto" last="Mannermaa">Arto Mannermaa</name>
<affiliation><nlm:aff id="A75">School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Biocenter Kuopio and Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kataja, Vesa" sort="Kataja, Vesa" uniqKey="Kataja V" first="Vesa" last="Kataja">Vesa Kataja</name>
<affiliation><nlm:aff id="A76">School of Medicine, Institute of Clinical Medicine, Oncology, University of Eastern Finland, Biocenter Kuopio and Department of Oncology, Kuopio University Hospital, Kuopio, Finland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kosma, Veli Matti" sort="Kosma, Veli Matti" uniqKey="Kosma V" first="Veli-Matti" last="Kosma">Veli-Matti Kosma</name>
<affiliation><nlm:aff id="A75">School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Biocenter Kuopio and Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hartikainen, Jaana M" sort="Hartikainen, Jaana M" uniqKey="Hartikainen J" first="Jaana M." last="Hartikainen">Jaana M. Hartikainen</name>
<affiliation><nlm:aff id="A75">School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Biocenter Kuopio and Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Radice, Paolo" sort="Radice, Paolo" uniqKey="Radice P" first="Paolo" last="Radice">Paolo Radice</name>
<affiliation><nlm:aff id="A77">Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predicted Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy and IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Peterlongo, Paolo" sort="Peterlongo, Paolo" uniqKey="Peterlongo P" first="Paolo" last="Peterlongo">Paolo Peterlongo</name>
<affiliation><nlm:aff id="A77">Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predicted Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy and IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Manoukian, Siranoush" sort="Manoukian, Siranoush" uniqKey="Manoukian S" first="Siranoush" last="Manoukian">Siranoush Manoukian</name>
<affiliation><nlm:aff id="A78">Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Bernard, Loris" sort="Bernard, Loris" uniqKey="Bernard L" first="Loris" last="Bernard">Loris Bernard</name>
<affiliation><nlm:aff id="A79">Department of Experimental Oncology, Istituto Europeo di Oncologia (IEO), Milan, Italy and Consortium for Genomics Technology (Cogentech) Milan, Italy</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Couch, Fergus J" sort="Couch, Fergus J" uniqKey="Couch F" first="Fergus J." last="Couch">Fergus J. Couch</name>
<affiliation><nlm:aff id="A80">Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Olson, Janet E" sort="Olson, Janet E" uniqKey="Olson J" first="Janet E." last="Olson">Janet E. Olson</name>
<affiliation><nlm:aff id="A81">Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Wang, Xianshu" sort="Wang, Xianshu" uniqKey="Wang X" first="Xianshu" last="Wang">Xianshu Wang</name>
<affiliation><nlm:aff id="A80">Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Fredericksen, Zachary" sort="Fredericksen, Zachary" uniqKey="Fredericksen Z" first="Zachary" last="Fredericksen">Zachary Fredericksen</name>
<affiliation><nlm:aff id="A81">Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Aln S, Grethe Grenaker" sort="Aln S, Grethe Grenaker" uniqKey="Aln S G" first="Grethe Grenaker" last="Aln S">Grethe Grenaker Aln S</name>
<affiliation><nlm:aff id="A82">Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo, Norway</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kristensen, Vessela" sort="Kristensen, Vessela" uniqKey="Kristensen V" first="Vessela" last="Kristensen">Vessela Kristensen</name>
<affiliation><nlm:aff id="A82">Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo, Norway</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A83">Faculty of Medicine (Faculty Division Ahus), UiO, Norway</nlm:aff>
</affiliation>
</author>
<author><name sortKey="B Rresen Dale, Anne Lise" sort="B Rresen Dale, Anne Lise" uniqKey="B Rresen Dale A" first="Anne-Lise" last="B Rresen-Dale">Anne-Lise B Rresen-Dale</name>
<affiliation><nlm:aff id="A82">Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo, Norway</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A83">Faculty of Medicine (Faculty Division Ahus), UiO, Norway</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Devilee, Peter" sort="Devilee, Peter" uniqKey="Devilee P" first="Peter" last="Devilee">Peter Devilee</name>
<affiliation><nlm:aff id="A84">Department of Human Genetics, and Department of Pathology, Leiden University Medical Centre, Leiden, The Netherlands</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Tollenaar, Robert A E M" sort="Tollenaar, Robert A E M" uniqKey="Tollenaar R" first="Robert A. E. M." last="Tollenaar">Robert A. E. M. Tollenaar</name>
<affiliation><nlm:aff id="A85">Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Seynaeve, Caroline M" sort="Seynaeve, Caroline M" uniqKey="Seynaeve C" first="Caroline M." last="Seynaeve">Caroline M. Seynaeve</name>
<affiliation><nlm:aff id="A86">Department of Medical Oncology, Rotterdam Family Cancer Clinic, Erasmus MC-Daniel den Hoed Cancer Center, Rotterdam, The Netherlands</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hooning, Maartje J" sort="Hooning, Maartje J" uniqKey="Hooning M" first="Maartje J." last="Hooning">Maartje J. Hooning</name>
<affiliation><nlm:aff id="A86">Department of Medical Oncology, Rotterdam Family Cancer Clinic, Erasmus MC-Daniel den Hoed Cancer Center, Rotterdam, The Netherlands</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Garcia Closas, Montserrat" sort="Garcia Closas, Montserrat" uniqKey="Garcia Closas M" first="Montserrat" last="García-Closas">Montserrat García-Closas</name>
<affiliation><nlm:aff id="A87">Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA; Division of Genetics and Epidemiology, Institute of Cancer Research and Breakthrough Breast Cancer Research Centre, London, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J." last="Chanock">Stephen J. Chanock</name>
<affiliation><nlm:aff id="A88">Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lissowska, Jolanta" sort="Lissowska, Jolanta" uniqKey="Lissowska J" first="Jolanta" last="Lissowska">Jolanta Lissowska</name>
<affiliation><nlm:aff id="A89">Department of Cancer Epidemiology and Prevention, M. Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Sherman, Mark E" sort="Sherman, Mark E" uniqKey="Sherman M" first="Mark E." last="Sherman">Mark E. Sherman</name>
<affiliation><nlm:aff id="A88">Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hall, Per" sort="Hall, Per" uniqKey="Hall P" first="Per" last="Hall">Per Hall</name>
<affiliation><nlm:aff id="A90">Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Liu, Jianjun" sort="Liu, Jianjun" uniqKey="Liu J" first="Jianjun" last="Liu">Jianjun Liu</name>
<affiliation><nlm:aff id="A90">Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Czene, Kamila" sort="Czene, Kamila" uniqKey="Czene K" first="Kamila" last="Czene">Kamila Czene</name>
<affiliation><nlm:aff id="A90">Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kang, Daehee" sort="Kang, Daehee" uniqKey="Kang D" first="Daehee" last="Kang">Daehee Kang</name>
<affiliation><nlm:aff id="A91">Seoul National University College of Medicine, Seoul, Korea</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Yoo, Keun Young" sort="Yoo, Keun Young" uniqKey="Yoo K" first="Keun-Young" last="Yoo">Keun-Young Yoo</name>
<affiliation><nlm:aff id="A91">Seoul National University College of Medicine, Seoul, Korea</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Noh, Dong Young" sort="Noh, Dong Young" uniqKey="Noh D" first="Dong-Young" last="Noh">Dong-Young Noh</name>
<affiliation><nlm:aff id="A91">Seoul National University College of Medicine, Seoul, Korea</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lindblom, Annika" sort="Lindblom, Annika" uniqKey="Lindblom A" first="Annika" last="Lindblom">Annika Lindblom</name>
<affiliation><nlm:aff id="A92">Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Margolin, Sara" sort="Margolin, Sara" uniqKey="Margolin S" first="Sara" last="Margolin">Sara Margolin</name>
<affiliation><nlm:aff id="A93">Department of Oncology Pathology, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Dunning, Alison M" sort="Dunning, Alison M" uniqKey="Dunning A" first="Alison M." last="Dunning">Alison M. Dunning</name>
<affiliation><nlm:aff id="A94">Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Pharoah, Paul D P" sort="Pharoah, Paul D P" uniqKey="Pharoah P" first="Paul D. P." last="Pharoah">Paul D. P. Pharoah</name>
<affiliation><nlm:aff id="A5">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A94">Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F." last="Easton">Douglas F. Easton</name>
<affiliation><nlm:aff id="A5">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A94">Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Guenel, Pascal" sort="Guenel, Pascal" uniqKey="Guenel P" first="Pascal" last="Guénel">Pascal Guénel</name>
<affiliation><nlm:aff id="A2">Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer Team, Villejuif, France</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A3">University Paris-Sud, UMRS 1018, Villejuif, France</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Brauch, Hiltrud" sort="Brauch, Hiltrud" uniqKey="Brauch H" first="Hiltrud" last="Brauch">Hiltrud Brauch</name>
<affiliation><nlm:aff id="A4">Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, and University Tübingen, Germany</nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Human Mutation</title>
<idno type="ISSN">1059-7794</idno>
<idno type="eISSN">1098-1004</idno>
<imprint><date when="2012">2012</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p id="P3">A recent two-stage genome-wide association study (GWAS) identified five novel breast cancer susceptibility loci on chromosomes 9, 10 and 11. To provide more reliable estimates of the relative risk associated with these loci and investigate possible heterogeneity by subtype of breast cancer, we genotyped the variants rs2380205, rs1011970, rs704010, rs614367, rs10995190 in 39 studies from the Breast Cancer Association Consortium (BCAC), involving 49,608 cases and 48,772 controls of predominantly European ancestry. Four of the variants showed clear evidence of association (<italic>P</italic>
≤ 3 × 10<sup>−9</sup>
) and weak evidence was observed for rs2380205 (<italic>P</italic>
= 0.06). The strongest evidence was obtained for rs614367, located on 11q13 (per-allele odds ratio 1.21, <italic>P</italic>
= 4 × 10<sup>−39</sup>
). The association for rs614367 was specific to estrogen receptor (ER)-positive disease and strongest for ER plus progesterone receptor (PR)-positive breast cancer, whereas the associations for the other three loci did not differ by tumor subtype.</p>
</div>
</front>
</TEI>
<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">9215429</journal-id>
<journal-id journal-id-type="pubmed-jr-id">2408</journal-id>
<journal-id journal-id-type="nlm-ta">Hum Mutat</journal-id>
<journal-id journal-id-type="iso-abbrev">Hum. Mutat.</journal-id>
<journal-title-group><journal-title>Human Mutation</journal-title>
</journal-title-group>
<issn pub-type="ppub">1059-7794</issn>
<issn pub-type="epub">1098-1004</issn>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">22461340</article-id>
<article-id pub-id-type="pmc">3370081</article-id>
<article-id pub-id-type="doi">10.1002/humu.22089</article-id>
<article-id pub-id-type="manuscript">NIHMS364885</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>11q13 is a Susceptibility Locus for Hormone Receptor Positive Breast Cancer<xref ref-type="fn" rid="FN3">†</xref>
</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Lambrechts</surname>
<given-names>Diether</given-names>
</name>
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<xref ref-type="author-notes" rid="FN1">*</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Truong</surname>
<given-names>Therese</given-names>
</name>
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<xref ref-type="aff" rid="A3">3</xref>
<xref ref-type="author-notes" rid="FN1">*</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Justenhoven</surname>
<given-names>Christina</given-names>
</name>
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<xref ref-type="author-notes" rid="FN1">*</xref>
</contrib>
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<given-names>Manjeet K.</given-names>
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<given-names>Melissa C.</given-names>
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</contrib>
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<given-names>Sten</given-names>
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</contrib>
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<given-names>Elinor</given-names>
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<given-names>Michael</given-names>
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</contrib>
<contrib contrib-type="author"><name><surname>Miller</surname>
<given-names>Nicola</given-names>
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</contrib>
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<given-names>Roger L.</given-names>
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</contrib>
<contrib contrib-type="author"><name><surname>Arias Pérez</surname>
<given-names>José Ignacio</given-names>
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<xref ref-type="aff" rid="A14">14</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Benítez</surname>
<given-names>Javier</given-names>
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</contrib>
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<given-names>Ute</given-names>
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<xref ref-type="aff" rid="A16">16</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Ko</surname>
<given-names>Yon-Dschun</given-names>
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</contrib>
<contrib contrib-type="author"><name><surname>Brüning</surname>
<given-names>Thomas</given-names>
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<xref ref-type="aff" rid="A18">18</xref>
</contrib>
<contrib contrib-type="author"><collab>The GENICA Network</collab>
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</contrib>
<contrib contrib-type="author"><name><surname>Chang-Claude</surname>
<given-names>Jenny</given-names>
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</contrib>
<contrib contrib-type="author"><name><surname>Eilber</surname>
<given-names>Ursel</given-names>
</name>
<xref ref-type="aff" rid="A20">20</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Hein</surname>
<given-names>Rebecca</given-names>
</name>
<xref ref-type="aff" rid="A20">20</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Nickels</surname>
<given-names>Stefan</given-names>
</name>
<xref ref-type="aff" rid="A20">20</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Flesch-Janys</surname>
<given-names>Dieter</given-names>
</name>
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</contrib>
<contrib contrib-type="author"><name><surname>Wang-Gohrke</surname>
<given-names>Shan</given-names>
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</contrib>
<contrib contrib-type="author"><name><surname>John</surname>
<given-names>Esther M.</given-names>
</name>
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</contrib>
<contrib contrib-type="author"><name><surname>Miron</surname>
<given-names>Alexander</given-names>
</name>
<xref ref-type="aff" rid="A24">24</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Winqvist</surname>
<given-names>Robert</given-names>
</name>
<xref ref-type="aff" rid="A25">25</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Pylkäs</surname>
<given-names>Katri</given-names>
</name>
<xref ref-type="aff" rid="A25">25</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Jukkola-Vuorinen</surname>
<given-names>Arja</given-names>
</name>
<xref ref-type="aff" rid="A26">26</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Grip</surname>
<given-names>Mervi</given-names>
</name>
<xref ref-type="aff" rid="A27">27</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Chenevix-Trench</surname>
<given-names>Georgia</given-names>
</name>
<xref ref-type="aff" rid="A28">28</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Beesley</surname>
<given-names>Jonathan</given-names>
</name>
<xref ref-type="aff" rid="A28">28</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Chen</surname>
<given-names>Xiaoqing</given-names>
</name>
<xref ref-type="aff" rid="A28">28</xref>
</contrib>
<contrib contrib-type="author"><collab>kConFab Investigators</collab>
<xref ref-type="aff" rid="A29">29</xref>
</contrib>
<contrib contrib-type="author"><collab>Australian Ovarian Cancer Study Group</collab>
<xref ref-type="aff" rid="A29">29</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Menegaux</surname>
<given-names>Florence</given-names>
</name>
<xref ref-type="aff" rid="A2">2</xref>
<xref ref-type="aff" rid="A3">3</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Cordina-Duverger</surname>
<given-names>Emilie</given-names>
</name>
<xref ref-type="aff" rid="A2">2</xref>
<xref ref-type="aff" rid="A3">3</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Shen</surname>
<given-names>Chen-Yang</given-names>
</name>
<xref ref-type="aff" rid="A30">30</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Yu</surname>
<given-names>Jyh-Cherng</given-names>
</name>
<xref ref-type="aff" rid="A31">31</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Wu</surname>
<given-names>Pei-Ei</given-names>
</name>
<xref ref-type="aff" rid="A30">30</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Hou</surname>
<given-names>Ming-Feng</given-names>
</name>
<xref ref-type="aff" rid="A32">32</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Andrulis</surname>
<given-names>Irene L.</given-names>
</name>
<xref ref-type="aff" rid="A33">33</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Selander</surname>
<given-names>Teresa</given-names>
</name>
<xref ref-type="aff" rid="A34">34</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Glendon</surname>
<given-names>Gord</given-names>
</name>
<xref ref-type="aff" rid="A34">34</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Mulligan</surname>
<given-names>Anna Marie</given-names>
</name>
<xref ref-type="aff" rid="A36">36</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Anton-Culver</surname>
<given-names>Hoda</given-names>
</name>
<xref ref-type="aff" rid="A37">37</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Ziogas</surname>
<given-names>Argyrios</given-names>
</name>
<xref ref-type="aff" rid="A37">37</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Muir</surname>
<given-names>Kenneth R.</given-names>
</name>
<xref ref-type="aff" rid="A38">38</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Lophatananon</surname>
<given-names>Artitaya</given-names>
</name>
<xref ref-type="aff" rid="A38">38</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Rattanamongkongul</surname>
<given-names>Suthee</given-names>
</name>
<xref ref-type="aff" rid="A39">39</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Puttawibul</surname>
<given-names>Puttisak</given-names>
</name>
<xref ref-type="aff" rid="A40">40</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Jones</surname>
<given-names>Michael</given-names>
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<xref ref-type="aff" rid="A41">41</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Orr</surname>
<given-names>Nicholas</given-names>
</name>
<xref ref-type="aff" rid="A42">42</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Ashworth</surname>
<given-names>Alan</given-names>
</name>
<xref ref-type="aff" rid="A42">42</xref>
</contrib>
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<given-names>Anthony</given-names>
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<xref ref-type="aff" rid="A41">41</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Severi</surname>
<given-names>Gianluca</given-names>
</name>
<xref ref-type="aff" rid="A43">43</xref>
</contrib>
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<given-names>Laura</given-names>
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<xref ref-type="aff" rid="A43">43</xref>
</contrib>
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<given-names>Graham</given-names>
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<xref ref-type="aff" rid="A6">6</xref>
<xref ref-type="aff" rid="A43">43</xref>
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<given-names>Melissa</given-names>
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<xref ref-type="aff" rid="A43">43</xref>
</contrib>
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<given-names>Federik</given-names>
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<xref ref-type="aff" rid="A44">44</xref>
<xref ref-type="aff" rid="A45">45</xref>
</contrib>
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<given-names>Andreas</given-names>
</name>
<xref ref-type="aff" rid="A44">44</xref>
<xref ref-type="aff" rid="A45">45</xref>
</contrib>
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<given-names>Christof</given-names>
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<xref ref-type="aff" rid="A45">45</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Burwinkel</surname>
<given-names>Barbara</given-names>
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<xref ref-type="aff" rid="A45">45</xref>
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</contrib>
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<given-names>Betul T.</given-names>
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<given-names>Robert</given-names>
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<xref ref-type="aff" rid="A47">47</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Wildiers</surname>
<given-names>Hans</given-names>
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<xref ref-type="aff" rid="A47">47</xref>
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<given-names>Hermann</given-names>
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<xref ref-type="aff" rid="A48">48</xref>
</contrib>
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<given-names>Heiko</given-names>
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<xref ref-type="aff" rid="A48">48</xref>
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<given-names>Volker</given-names>
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<xref ref-type="aff" rid="A48">48</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Stegmaier</surname>
<given-names>Christa</given-names>
</name>
<xref ref-type="aff" rid="A49">49</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Meindl</surname>
<given-names>Alfons</given-names>
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</contrib>
<contrib contrib-type="author"><name><surname>Schott</surname>
<given-names>Sarah</given-names>
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<given-names>Claus R.</given-names>
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<given-names>Rita K.</given-names>
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</contrib>
<contrib contrib-type="author"><name><surname>Brock</surname>
<given-names>Ian W.</given-names>
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</contrib>
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<given-names>Graeme</given-names>
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</contrib>
<contrib contrib-type="author"><name><surname>Cross</surname>
<given-names>Simon S.</given-names>
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</contrib>
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<given-names>Peter A.</given-names>
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</contrib>
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<given-names>Ruediger</given-names>
</name>
<xref ref-type="aff" rid="A58">58</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Ekici</surname>
<given-names>Arif B.</given-names>
</name>
<xref ref-type="aff" rid="A59">59</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Beckmann</surname>
<given-names>Matthias W.</given-names>
</name>
<xref ref-type="aff" rid="A60">60</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Fletcher</surname>
<given-names>Olivia</given-names>
</name>
<xref ref-type="aff" rid="A61">61</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Johnson</surname>
<given-names>Nichola</given-names>
</name>
<xref ref-type="aff" rid="A61">61</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Silva</surname>
<given-names>Isabel dos Santos</given-names>
</name>
<xref ref-type="aff" rid="A62">62</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Peto</surname>
<given-names>Julian</given-names>
</name>
<xref ref-type="aff" rid="A62">62</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Nevanlinna</surname>
<given-names>Heli</given-names>
</name>
<xref ref-type="aff" rid="A63">63</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Muranen</surname>
<given-names>Taru A.</given-names>
</name>
<xref ref-type="aff" rid="A63">63</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Aittomäki</surname>
<given-names>Kristiina</given-names>
</name>
<xref ref-type="aff" rid="A64">64</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Blomqvist</surname>
<given-names>Carl</given-names>
</name>
<xref ref-type="aff" rid="A65">65</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Dörk</surname>
<given-names>Thilo</given-names>
</name>
<xref ref-type="aff" rid="A66">66</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Schürmann</surname>
<given-names>Peter</given-names>
</name>
<xref ref-type="aff" rid="A66">66</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Bremer</surname>
<given-names>Michael</given-names>
</name>
<xref ref-type="aff" rid="A67">67</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Hillemanns</surname>
<given-names>Peter</given-names>
</name>
<xref ref-type="aff" rid="A66">66</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Bogdanova</surname>
<given-names>Natalia V.</given-names>
</name>
<xref ref-type="aff" rid="A66">66</xref>
<xref ref-type="aff" rid="A67">67</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Antonenkova</surname>
<given-names>Natalia N.</given-names>
</name>
<xref ref-type="aff" rid="A68">68</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Rogov</surname>
<given-names>Yuri I.</given-names>
</name>
<xref ref-type="aff" rid="A68">68</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Karstens</surname>
<given-names>Johann H.</given-names>
</name>
<xref ref-type="aff" rid="A66">66</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Khusnutdinova</surname>
<given-names>Elza</given-names>
</name>
<xref ref-type="aff" rid="A69">69</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Bermisheva</surname>
<given-names>Marina</given-names>
</name>
<xref ref-type="aff" rid="A69">69</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Prokofieva</surname>
<given-names>Darya</given-names>
</name>
<xref ref-type="aff" rid="A69">69</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Gancev</surname>
<given-names>Shamil</given-names>
</name>
<xref ref-type="aff" rid="A70">70</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Jakubowska</surname>
<given-names>Anna</given-names>
</name>
<xref ref-type="aff" rid="A71">71</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Lubinski</surname>
<given-names>Jan</given-names>
</name>
<xref ref-type="aff" rid="A71">71</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Jaworska</surname>
<given-names>Katarzyna</given-names>
</name>
<xref ref-type="aff" rid="A71">71</xref>
<xref ref-type="aff" rid="A72">72</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Durda</surname>
<given-names>Katarzyna</given-names>
</name>
<xref ref-type="aff" rid="A71">71</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Nordestgaard</surname>
<given-names>Børge G.</given-names>
</name>
<xref ref-type="aff" rid="A73">73</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Bojesen</surname>
<given-names>Stig E.</given-names>
</name>
<xref ref-type="aff" rid="A73">73</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Lanng</surname>
<given-names>Charlotte</given-names>
</name>
<xref ref-type="aff" rid="A74">74</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Mannermaa</surname>
<given-names>Arto</given-names>
</name>
<xref ref-type="aff" rid="A75">75</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kataja</surname>
<given-names>Vesa</given-names>
</name>
<xref ref-type="aff" rid="A76">76</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kosma</surname>
<given-names>Veli-Matti</given-names>
</name>
<xref ref-type="aff" rid="A75">75</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Hartikainen</surname>
<given-names>Jaana M.</given-names>
</name>
<xref ref-type="aff" rid="A75">75</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Radice</surname>
<given-names>Paolo</given-names>
</name>
<xref ref-type="aff" rid="A77">77</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Peterlongo</surname>
<given-names>Paolo</given-names>
</name>
<xref ref-type="aff" rid="A77">77</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Manoukian</surname>
<given-names>Siranoush</given-names>
</name>
<xref ref-type="aff" rid="A78">78</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Bernard</surname>
<given-names>Loris</given-names>
</name>
<xref ref-type="aff" rid="A79">79</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Couch</surname>
<given-names>Fergus J.</given-names>
</name>
<xref ref-type="aff" rid="A80">80</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Olson</surname>
<given-names>Janet E.</given-names>
</name>
<xref ref-type="aff" rid="A81">81</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Wang</surname>
<given-names>Xianshu</given-names>
</name>
<xref ref-type="aff" rid="A80">80</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Fredericksen</surname>
<given-names>Zachary</given-names>
</name>
<xref ref-type="aff" rid="A81">81</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Alnæs</surname>
<given-names>Grethe Grenaker</given-names>
</name>
<xref ref-type="aff" rid="A82">82</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kristensen</surname>
<given-names>Vessela</given-names>
</name>
<xref ref-type="aff" rid="A82">82</xref>
<xref ref-type="aff" rid="A83">83</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Børresen-Dale</surname>
<given-names>Anne-Lise</given-names>
</name>
<xref ref-type="aff" rid="A82">82</xref>
<xref ref-type="aff" rid="A83">83</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Devilee</surname>
<given-names>Peter</given-names>
</name>
<xref ref-type="aff" rid="A84">84</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Tollenaar</surname>
<given-names>Robert A.E.M.</given-names>
</name>
<xref ref-type="aff" rid="A85">85</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Seynaeve</surname>
<given-names>Caroline M.</given-names>
</name>
<xref ref-type="aff" rid="A86">86</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Hooning</surname>
<given-names>Maartje J.</given-names>
</name>
<xref ref-type="aff" rid="A86">86</xref>
</contrib>
<contrib contrib-type="author"><name><surname>García-Closas</surname>
<given-names>Montserrat</given-names>
</name>
<xref ref-type="aff" rid="A87">87</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Chanock</surname>
<given-names>Stephen J.</given-names>
</name>
<xref ref-type="aff" rid="A88">88</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Lissowska</surname>
<given-names>Jolanta</given-names>
</name>
<xref ref-type="aff" rid="A89">89</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Sherman</surname>
<given-names>Mark E.</given-names>
</name>
<xref ref-type="aff" rid="A88">88</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Hall</surname>
<given-names>Per</given-names>
</name>
<xref ref-type="aff" rid="A90">90</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Liu</surname>
<given-names>Jianjun</given-names>
</name>
<xref ref-type="aff" rid="A90">90</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Czene</surname>
<given-names>Kamila</given-names>
</name>
<xref ref-type="aff" rid="A90">90</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kang</surname>
<given-names>Daehee</given-names>
</name>
<xref ref-type="aff" rid="A91">91</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Yoo</surname>
<given-names>Keun-Young</given-names>
</name>
<xref ref-type="aff" rid="A91">91</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Noh</surname>
<given-names>Dong-Young</given-names>
</name>
<xref ref-type="aff" rid="A91">91</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Lindblom</surname>
<given-names>Annika</given-names>
</name>
<xref ref-type="aff" rid="A92">92</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Margolin</surname>
<given-names>Sara</given-names>
</name>
<xref ref-type="aff" rid="A93">93</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Dunning</surname>
<given-names>Alison M.</given-names>
</name>
<xref ref-type="aff" rid="A94">94</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Pharoah</surname>
<given-names>Paul D.P.</given-names>
</name>
<xref ref-type="aff" rid="A5">5</xref>
<xref ref-type="aff" rid="A94">94</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Easton</surname>
<given-names>Douglas F.</given-names>
</name>
<xref ref-type="aff" rid="A5">5</xref>
<xref ref-type="aff" rid="A94">94</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Guénel</surname>
<given-names>Pascal</given-names>
</name>
<xref ref-type="aff" rid="A2">2</xref>
<xref ref-type="aff" rid="A3">3</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Brauch</surname>
<given-names>Hiltrud</given-names>
</name>
<xref ref-type="aff" rid="A4">4</xref>
</contrib>
</contrib-group>
<aff id="A1"><label>1</label>
Vesalius Research Center (VRC), VIB, KULeuven, Belgium</aff>
<aff id="A2"><label>2</label>
Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer Team, Villejuif, France</aff>
<aff id="A3"><label>3</label>
University Paris-Sud, UMRS 1018, Villejuif, France</aff>
<aff id="A4"><label>4</label>
Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, and University Tübingen, Germany</aff>
<aff id="A5"><label>5</label>
Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK</aff>
<aff id="A6"><label>6</label>
Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia</aff>
<aff id="A7"><label>7</label>
Department of Pathology, The University of Melbourne, Melbourne, Australia</aff>
<aff id="A8"><label>8</label>
Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands</aff>
<aff id="A9"><label>9</label>
Division of Cancer Studies, NIHR Comprehensive Biomedical Research Centre, Guy's & St. Thomas' NHS Foundation Trust in partnership with King's College London, London, United Kingdom</aff>
<aff id="A10"><label>10</label>
Welcome Trust Centre for Human Genetics and Oxford Biomedical Research Centre, University of Oxford, United Kingdom</aff>
<aff id="A11"><label>11</label>
Clinical Science Institute. University Hospital Galway, Galway, Ireland</aff>
<aff id="A12"><label>12</label>
Genetic and Molecular Epidemiology Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain</aff>
<aff id="A13"><label>13</label>
Servicio de Oncología Médica, Hospital Universitario La Paz, Madrid, Spain</aff>
<aff id="A14"><label>14</label>
Servicio de Cirugía General y Especialidades, Hospital Monte Naranco, Oviedo, Spain</aff>
<aff id="A15"><label>15</label>
Human Genetics Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain</aff>
<aff id="A16"><label>16</label>
Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany</aff>
<aff id="A17"><label>17</label>
Department of Internal Medicine, Evangelische Kliniken Bonn gGmbH, Johanniter Krankenhaus, Bonn, Germany</aff>
<aff id="A18"><label>18</label>
Institute for Prevention and Occupational Medicine of the German Social Accident Insurance (IPA), Bochum, Germany</aff>
<aff id="A19"><label>19</label>
Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, and University Tübingen, Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Department of Internal Medicine, Evangelische Kliniken Bonn gGmbH, Johanniter Krankenhaus, Bonn, Institute of Pathology, Medical Faculty of the University of Bonn, Bonn, Germany, Institute for Prevention and Occupational Medicine of the German Social Accident Insurance (IPA), Bochum, Germany; Institute and Outpatient Clinic of Occupational Medicine, Saarland University Medical Center and Saarland University Faculty of Medicine, Homburg, German</aff>
<aff id="A20"><label>20</label>
Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</aff>
<aff id="A21"><label>21</label>
Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg, Germany</aff>
<aff id="A22"><label>22</label>
Department of Obstetrics and Gynecology, University of Ulm, Ulm, Germany</aff>
<aff id="A23"><label>23</label>
Cancer Prevention Institute of California, Fremont, CA, USA and Stanford University School of Medicine and Stanford Cancer Institute, Stanford, CA, USA</aff>
<aff id="A24"><label>24</label>
Dana-Farber Cancer Institute, Boston, Massachusetts, USA</aff>
<aff id="A25"><label>25</label>
Laboratory of Cancer Genetics, Department of Clinical Genetics and Biocenter Oulu, University of Oulu, Oulu, Finland</aff>
<aff id="A26"><label>26</label>
Department of Oncology, Oulu University Hospital, University of Oulu, Oulu, Finland</aff>
<aff id="A27"><label>27</label>
Department of Surgery, Oulu University Hospital, University of Oulu, Oulu, Finland</aff>
<aff id="A28"><label>28</label>
Queensland Institute of Medical Research, Brisbane, Australia</aff>
<aff id="A29"><label>29</label>
Peter MacCallum Cancer Center, Melbourne, Australia</aff>
<aff id="A30"><label>30</label>
Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan; Taiwan Biobank, Taipei, Taiwan</aff>
<aff id="A31"><label>31</label>
Department of Surgery, Tri-Service General Hospital, Taipei, Taiwan</aff>
<aff id="A32"><label>32</label>
Cancer Center and Department of Surgery, Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Taiwan</aff>
<aff id="A33"><label>33</label>
Ontario Cancer Genetics Network, Cancer Care Ontario; Fred A. Litwin Center for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada</aff>
<aff id="A34"><label>34</label>
Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada</aff>
<aff id="A35"><label>35</label>
Ontario Cancer Genetics Network, Cancer Care Ontario, Toronto, Ontario, Canada</aff>
<aff id="A36"><label>36</label>
Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada</aff>
<aff id="A37"><label>37</label>
Department of Epidemiology, University of California Irvine, Irvine, California, USA</aff>
<aff id="A38"><label>38</label>
Health Sciences Research Institute, Warwick Medical School, Warwick University, Coventry, UK</aff>
<aff id="A39"><label>39</label>
Department of Preventive Medicine, Srinakhrainwirot University, Ongkharak, Nakhon Nayok, Thailand</aff>
<aff id="A40"><label>40</label>
Department of Surgery, Medical School, Prince Songkla University, Songkla, Thailand</aff>
<aff id="A41"><label>41</label>
Section of Epidemiology, The Institute of Cancer Research, Sutton, Surrey, UK</aff>
<aff id="A42"><label>42</label>
Breakthrough Breast Cancer Research Centre, Chester Beatty Laboratories, The Institute of Cancer Research, London, UK</aff>
<aff id="A43"><label>43</label>
Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia</aff>
<aff id="A44"><label>44</label>
National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany</aff>
<aff id="A45"><label>45</label>
Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</aff>
<aff id="A46"><label>46</label>
Molecular Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany</aff>
<aff id="A47"><label>47</label>
Multidisciplinary Breast Center, University Hospital Gasthuisberg, Leuven, Belgium</aff>
<aff id="A48"><label>48</label>
Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany</aff>
<aff id="A49"><label>49</label>
Saarland Cancer Registry, Saarbrücken, Germany</aff>
<aff id="A50"><label>50</label>
Division of Gynaecology and Obstetrics, Technical University of Munich, Munich, Germany</aff>
<aff id="A51"><label>51</label>
Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</aff>
<aff id="A52"><label>52</label>
Institute of Human Genetics, University of Heidelberg, Heidelberg, Germany</aff>
<aff id="A53"><label>53</label>
Division of Molecular Gyneco-Oncology, Department of Gynaecology and Obstetrics, Center of Molecular Medicine Cologne (CMMC), University Hospital of Cologne, Cologne, Germany</aff>
<aff id="A54"><label>54</label>
Institute for Cancer Studies, Department of Oncology, University of Sheffield, UK</aff>
<aff id="A55"><label>55</label>
Institute for Cancer Studies, Department of Oncology, University of Sheffield, UK; current address: University of Manchester, Manchester, UK</aff>
<aff id="A56"><label>56</label>
Academic Unit of Pathology, Department of Neuroscience, University of Sheffield, UK</aff>
<aff id="A57"><label>57</label>
University Breast Center, Department of Gynecology and Obstetrics, University Hospital Erlangen, Erlangen, Germany; David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology, University of California at Los Angeles, CA, USA</aff>
<aff id="A58"><label>58</label>
Institute of Diagnostic Radiology, University Hospital Erlangen, Erlangen, Germany</aff>
<aff id="A59"><label>59</label>
Institute of Human Genetics, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany</aff>
<aff id="A60"><label>60</label>
University Breast Center, Department of Gynecology and Obstetrics, University Hospital Erlangen, Erlangen, Germany</aff>
<aff id="A61"><label>61</label>
Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK</aff>
<aff id="A62"><label>62</label>
London School of Hygiene and Tropical Medicine, London, UK</aff>
<aff id="A63"><label>63</label>
Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Biomedicum Helsinki, Helsinki, Finland</aff>
<aff id="A64"><label>64</label>
Department of Clinical Genetics, Helsinki University Central Hospital, Helsinki, Finland</aff>
<aff id="A65"><label>65</label>
Department of Oncology, Helsinki University Central Hospital, Helsinki, Finland</aff>
<aff id="A66"><label>66</label>
Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany</aff>
<aff id="A67"><label>67</label>
Department of Radiation Oncology, Hannover Medical School, Hannover, Germany</aff>
<aff id="A68"><label>68</label>
N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus</aff>
<aff id="A69"><label>69</label>
Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Ufa, Russia</aff>
<aff id="A70"><label>70</label>
Bashkirian Medical University, Ufa, Russia</aff>
<aff id="A71"><label>71</label>
Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland</aff>
<aff id="A72"><label>72</label>
Postgraduate School of Molecular Medicine, Warsaw Medical University, Warsaw, Poland</aff>
<aff id="A73"><label>73</label>
Copenhagen General Population Study and Department of Clinical Biochemistry, Herlev University Hospital, University of Copenhagen, Copenhagen, Denmark</aff>
<aff id="A74"><label>74</label>
Department of Breast Surgery, Herlev University Hospital, University of Copenhagen, Copenhagen, Denmark</aff>
<aff id="A75"><label>75</label>
School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Biocenter Kuopio and Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland</aff>
<aff id="A76"><label>76</label>
School of Medicine, Institute of Clinical Medicine, Oncology, University of Eastern Finland, Biocenter Kuopio and Department of Oncology, Kuopio University Hospital, Kuopio, Finland</aff>
<aff id="A77"><label>77</label>
Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predicted Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy and IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy</aff>
<aff id="A78"><label>78</label>
Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy</aff>
<aff id="A79"><label>79</label>
Department of Experimental Oncology, Istituto Europeo di Oncologia (IEO), Milan, Italy and Consortium for Genomics Technology (Cogentech) Milan, Italy</aff>
<aff id="A80"><label>80</label>
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA</aff>
<aff id="A81"><label>81</label>
Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA</aff>
<aff id="A82"><label>82</label>
Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo, Norway</aff>
<aff id="A83"><label>83</label>
Faculty of Medicine (Faculty Division Ahus), UiO, Norway</aff>
<aff id="A84"><label>84</label>
Department of Human Genetics, and Department of Pathology, Leiden University Medical Centre, Leiden, The Netherlands</aff>
<aff id="A85"><label>85</label>
Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands</aff>
<aff id="A86"><label>86</label>
Department of Medical Oncology, Rotterdam Family Cancer Clinic, Erasmus MC-Daniel den Hoed Cancer Center, Rotterdam, The Netherlands</aff>
<aff id="A87"><label>87</label>
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA; Division of Genetics and Epidemiology, Institute of Cancer Research and Breakthrough Breast Cancer Research Centre, London, UK</aff>
<aff id="A88"><label>88</label>
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</aff>
<aff id="A89"><label>89</label>
Department of Cancer Epidemiology and Prevention, M. Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland</aff>
<aff id="A90"><label>90</label>
Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden</aff>
<aff id="A91"><label>91</label>
Seoul National University College of Medicine, Seoul, Korea</aff>
<aff id="A92"><label>92</label>
Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden</aff>
<aff id="A93"><label>93</label>
Department of Oncology Pathology, Karolinska Institutet, Stockholm, Sweden</aff>
<aff id="A94"><label>94</label>
Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK</aff>
<author-notes><corresp id="cor1">Corresponding Author, Hiltrud Brauch, Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Auerbachstr. 112, 70376 Stuttgart, Germany, Tel.: 049 711 8101 3705; Fax: 049 711 85 92 95; <email>hiltrud.brauch@ikp-stuttgart.de</email>
</corresp>
<fn id="FN1" fn-type="equal"><label>*</label>
<p id="P1">contributed equally</p>
</fn>
<fn id="FN2"><p id="P2">Writing Group: Diether Lambrechts, Therese Truong, Christina Justenhoven, Douglas F. Easton, Pascal Guénel and Hiltrud Brauch</p>
</fn>
</author-notes>
<pub-date pub-type="nihms-submitted"><day>29</day>
<month>3</month>
<year>2012</year>
</pub-date>
<pub-date pub-type="epub"><day>30</day>
<month>4</month>
<year>2012</year>
</pub-date>
<pub-date pub-type="ppub"><month>7</month>
<year>2012</year>
</pub-date>
<pub-date pub-type="pmc-release"><day>01</day>
<month>7</month>
<year>2013</year>
</pub-date>
<volume>33</volume>
<issue>7</issue>
<fpage>1123</fpage>
<lpage>1132</lpage>
<abstract><p id="P3">A recent two-stage genome-wide association study (GWAS) identified five novel breast cancer susceptibility loci on chromosomes 9, 10 and 11. To provide more reliable estimates of the relative risk associated with these loci and investigate possible heterogeneity by subtype of breast cancer, we genotyped the variants rs2380205, rs1011970, rs704010, rs614367, rs10995190 in 39 studies from the Breast Cancer Association Consortium (BCAC), involving 49,608 cases and 48,772 controls of predominantly European ancestry. Four of the variants showed clear evidence of association (<italic>P</italic>
≤ 3 × 10<sup>−9</sup>
) and weak evidence was observed for rs2380205 (<italic>P</italic>
= 0.06). The strongest evidence was obtained for rs614367, located on 11q13 (per-allele odds ratio 1.21, <italic>P</italic>
= 4 × 10<sup>−39</sup>
). The association for rs614367 was specific to estrogen receptor (ER)-positive disease and strongest for ER plus progesterone receptor (PR)-positive breast cancer, whereas the associations for the other three loci did not differ by tumor subtype.</p>
</abstract>
<kwd-group><kwd>breast cancer susceptibility</kwd>
<kwd>polymorphisms</kwd>
<kwd>genome wide association</kwd>
<kwd>risk factors</kwd>
<kwd>hormone receptor status</kwd>
<kwd>11q13</kwd>
</kwd-group>
<funding-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source>
<award-id>U01 CA069417-16 || CA</award-id>
</award-group>
<award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source>
<award-id>U01 CA069417-15 || CA</award-id>
</award-group>
<award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source>
<award-id>U01 CA069417-14 || CA</award-id>
</award-group>
<award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source>
<award-id>U01 CA069417-12 || CA</award-id>
</award-group>
<award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source>
<award-id>U01 CA069417-10 || CA</award-id>
</award-group>
<award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source>
<award-id>U01 CA058860-09 || CA</award-id>
</award-group>
<award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source>
<award-id>R01 CA128978-04 || CA</award-id>
</award-group>
<award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source>
<award-id>R01 CA128978-03 || CA</award-id>
</award-group>
<award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source>
<award-id>R01 CA128978-02 || CA</award-id>
</award-group>
<award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source>
<award-id>R01 CA128978-01A2 || CA</award-id>
</award-group>
<award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source>
<award-id>R01 CA122340-05 || CA</award-id>
</award-group>
<award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source>
<award-id>R01 CA122340-04 || CA</award-id>
</award-group>
<award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source>
<award-id>R01 CA122340-03S1 || CA</award-id>
</award-group>
<award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source>
<award-id>R01 CA122340-03 || CA</award-id>
</award-group>
<award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source>
<award-id>R01 CA122340-02 || CA</award-id>
</award-group>
<award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source>
<award-id>R01 CA122340-01A1 || CA</award-id>
</award-group>
<award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source>
<award-id>R01 CA058860-14 || CA</award-id>
</award-group>
<award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source>
<award-id>R01 CA058860-13 || CA</award-id>
</award-group>
<award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source>
<award-id>R01 CA058860-11 || CA</award-id>
</award-group>
<award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source>
<award-id>P50 CA116201-01 || CA</award-id>
</award-group>
<award-group><funding-source country="United States">Division of Cancer Epidemiology and Genetics : NCI</funding-source>
<award-id>ZIC CP010178-08 || CP</award-id>
</award-group>
<award-group><funding-source country="United States">Division of Cancer Epidemiology and Genetics : NCI</funding-source>
<award-id>ZIA CP010187-05 || CP</award-id>
</award-group>
<award-group><funding-source country="United States">Division of Cancer Epidemiology and Genetics : NCI</funding-source>
<award-id>ZIA CP010126-14 || CP</award-id>
</award-group>
<award-group><funding-source country="United States">Division of Cancer Epidemiology and Genetics : NCI</funding-source>
<award-id>Z01 CP010178-06 || CP</award-id>
</award-group>
<award-group><funding-source country="United States">Division of Cancer Epidemiology and Genetics : NCI</funding-source>
<award-id>Z01 CP010126-13 || CP</award-id>
</award-group>
<award-group><funding-source country="United States">Division of Cancer Epidemiology and Genetics : NCI</funding-source>
<award-id>Z01 CP010126-12 || CP</award-id>
</award-group>
</funding-group>
</article-meta>
</front>
</pmc>
</record>
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