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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Dietary intake of acrylamide and epithelial ovarian cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort</title><author><name sortKey="Ob N Santacana, Mireia" sort="Ob N Santacana, Mireia" uniqKey="Ob N Santacana M" first="Mireia" last="Ob N-Santacana">Mireia Ob N-Santacana</name><affiliation><nlm:aff id="A1">Unit of Nutrition, Environment and Cancer. Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO-IDIBELL), Barcelona, Spain</nlm:aff></affiliation></author><author><name sortKey="Peeters, Petra H M" sort="Peeters, Petra H M" uniqKey="Peeters P" first="Petra H. M." last="Peeters">Petra H. M. Peeters</name><affiliation><nlm:aff id="A2">Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom</nlm:aff></affiliation><affiliation><nlm:aff id="A3">Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Freisling, Heinz" sort="Freisling, Heinz" uniqKey="Freisling H" first="Heinz" last="Freisling">Heinz Freisling</name><affiliation><nlm:aff id="A4">Dietary Exposure Assessment Group, International Agency for Research on Cancer, 150 Cours Albert Thomas, Lyon 69372, France Lyon, France.</nlm:aff></affiliation></author><author><name sortKey="Dossus, Laure" sort="Dossus, Laure" uniqKey="Dossus L" first="Laure" last="Dossus">Laure Dossus</name><affiliation><nlm:aff id="A5">Inserm, Centre for research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women’s Health team, F-94805, Villejuif, France</nlm:aff></affiliation><affiliation><nlm:aff id="A6">Univ Paris Sud, UMRS 1018, F-94805, Villejuif, France</nlm:aff></affiliation><affiliation><nlm:aff id="A7">IGR, F-94805, Villejuif, France</nlm:aff></affiliation></author><author><name sortKey="Clavel Chapelon, Francoise" sort="Clavel Chapelon, Francoise" uniqKey="Clavel Chapelon F" first="Françoise" last="Clavel-Chapelon">Françoise Clavel-Chapelon</name><affiliation><nlm:aff id="A5">Inserm, Centre for research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women’s Health team, F-94805, Villejuif, France</nlm:aff></affiliation><affiliation><nlm:aff id="A6">Univ Paris Sud, UMRS 1018, F-94805, Villejuif, France</nlm:aff></affiliation><affiliation><nlm:aff id="A7">IGR, F-94805, Villejuif, France</nlm:aff></affiliation></author><author><name sortKey="Baglietto, Laura" sort="Baglietto, Laura" uniqKey="Baglietto L" first="Laura" last="Baglietto">Laura Baglietto</name><affiliation><nlm:aff id="A8">Cancer Epidemiology Centre, Cancer Council of Victoria, Melbourne, Australia.</nlm:aff></affiliation><affiliation><nlm:aff id="A9">Centre for Epidemiology and Biostatistics, School of Population and Global Health, University of Melbourne, Australia.</nlm:aff></affiliation></author><author><name sortKey="Schock, Helena" sort="Schock, Helena" uniqKey="Schock H" first="Helena" last="Schock">Helena Schock</name><affiliation><nlm:aff id="A10">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Fortner, Renee T" sort="Fortner, Renee T" uniqKey="Fortner R" first="Renée T." last="Fortner">Renée T. Fortner</name><affiliation><nlm:aff id="A10">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Boeing, Heiner" sort="Boeing, Heiner" uniqKey="Boeing H" first="Heiner" last="Boeing">Heiner Boeing</name><affiliation><nlm:aff id="A11">Department of Epidemiology, German Institute of Human Nutrition, Potsdam-Rehbruecke, Nuthetal, Germany</nlm:aff></affiliation></author><author><name sortKey="Tj Nneland, Anne" sort="Tj Nneland, Anne" uniqKey="Tj Nneland A" first="Anne" last="Tj Nneland">Anne Tj Nneland</name><affiliation><nlm:aff id="A12">Danish Cancer Society Research Center, Copenhagen, Denmark</nlm:aff></affiliation></author><author><name sortKey="Olsen, Anja" sort="Olsen, Anja" uniqKey="Olsen A" first="Anja" last="Olsen">Anja Olsen</name><affiliation><nlm:aff id="A12">Danish Cancer Society Research Center, Copenhagen, Denmark</nlm:aff></affiliation></author><author><name sortKey="Overvad, Kim" sort="Overvad, Kim" uniqKey="Overvad K" first="Kim" last="Overvad">Kim Overvad</name><affiliation><nlm:aff id="A13">Department of Public Health, Section for Epidemiology, Aarhus University, Aarhus, Denmark</nlm:aff></affiliation></author><author><name sortKey="Menendez, Virginia" sort="Menendez, Virginia" uniqKey="Menendez V" first="Virginia" last="Menéndez">Virginia Menéndez</name><affiliation><nlm:aff id="A14">Public Health Directorate, Asturias, Spain</nlm:aff></affiliation></author><author><name sortKey="Sanchez, Maria Jose" sort="Sanchez, Maria Jose" uniqKey="Sanchez M" first="Maria-José" last="Sanchez">Maria-José Sanchez</name><affiliation><nlm:aff id="A15">Escuela Andaluza de Salud Pública. Instituto de Investigación Biosanitaria de Granada (Granada.ibs), Granada (Spain)</nlm:aff></affiliation><affiliation><nlm:aff id="A16">Consortium for Biomedical Research in Epidemiology and Public Health (CIBER Epidemiología y Salud Pública-CIBERESP), Madrid, Spain</nlm:aff></affiliation></author><author><name sortKey="Larra Aga, Nerea" sort="Larra Aga, Nerea" uniqKey="Larra Aga N" first="Nerea" last="Larra Aga">Nerea Larra Aga</name><affiliation><nlm:aff id="A16">Consortium for Biomedical Research in Epidemiology and Public Health (CIBER Epidemiología y Salud Pública-CIBERESP), Madrid, Spain</nlm:aff></affiliation><affiliation><nlm:aff id="A17">Public Health Division of Gipuzkoa-BIODONOSTIA, Basque Regional Health Department, Spain</nlm:aff></affiliation></author><author><name sortKey="Casta O, Jose Maria Huerta" sort="Casta O, Jose Maria Huerta" uniqKey="Casta O J" first="José María Huerta" last="Casta O">José María Huerta Casta O</name><affiliation><nlm:aff id="A16">Consortium for Biomedical Research in Epidemiology and Public Health (CIBER Epidemiología y Salud Pública-CIBERESP), Madrid, Spain</nlm:aff></affiliation><affiliation><nlm:aff id="A18">Department of Epidemiology, Murcia Regional Health Council, Murcia, Spain</nlm:aff></affiliation></author><author><name sortKey="Barricarte, Aurelio" sort="Barricarte, Aurelio" uniqKey="Barricarte A" first="Aurelio" last="Barricarte">Aurelio Barricarte</name><affiliation><nlm:aff id="A16">Consortium for Biomedical Research in Epidemiology and Public Health (CIBER Epidemiología y Salud Pública-CIBERESP), Madrid, Spain</nlm:aff></affiliation><affiliation><nlm:aff id="A19">Navarre Public Health Institute, Pamplona, Spain</nlm:aff></affiliation></author><author><name sortKey="Khaw, Kay Tee" sort="Khaw, Kay Tee" uniqKey="Khaw K" first="Kay-Tee" last="Khaw">Kay-Tee Khaw</name><affiliation><nlm:aff id="A20">University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Wareham, Nick" sort="Wareham, Nick" uniqKey="Wareham N" first="Nick" last="Wareham">Nick Wareham</name><affiliation><nlm:aff id="A21">MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Travis, Ruth C" sort="Travis, Ruth C" uniqKey="Travis R" first="Ruth C." last="Travis">Ruth C. Travis</name><affiliation><nlm:aff id="A22">Cancer Epidemiology Unit, Nuffield Department of Population Health University of Oxford, Oxford, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Merritt, Melissa A" sort="Merritt, Melissa A" uniqKey="Merritt M" first="Melissa A." last="Merritt">Melissa A. Merritt</name><affiliation><nlm:aff id="A2">Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Trichopoulou, Antonia" sort="Trichopoulou, Antonia" uniqKey="Trichopoulou A" first="Antonia" last="Trichopoulou">Antonia Trichopoulou</name><affiliation><nlm:aff id="A23">Hellenic Health Foundation, 13 Kaisareias Street, Athens, GR-115 27, Greece</nlm:aff></affiliation><affiliation><nlm:aff id="A24">Bureau of Epidemiologic Research, Academy of Athens, 23 Alexandroupoleos Street, Athens, GR-115 27, Greece</nlm:aff></affiliation></author><author><name sortKey="Trichopoulos, Dimitrios" sort="Trichopoulos, Dimitrios" uniqKey="Trichopoulos D" first="Dimitrios" last="Trichopoulos">Dimitrios Trichopoulos</name><affiliation><nlm:aff id="A23">Hellenic Health Foundation, 13 Kaisareias Street, Athens, GR-115 27, Greece</nlm:aff></affiliation><affiliation><nlm:aff id="A24">Bureau of Epidemiologic Research, Academy of Athens, 23 Alexandroupoleos Street, Athens, GR-115 27, Greece</nlm:aff></affiliation><affiliation><nlm:aff id="A25">Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA</nlm:aff></affiliation></author><author><name sortKey="Orfanos, Philippos" sort="Orfanos, Philippos" uniqKey="Orfanos P" first="Philippos" last="Orfanos">Philippos Orfanos</name><affiliation><nlm:aff id="A23">Hellenic Health Foundation, 13 Kaisareias Street, Athens, GR-115 27, Greece</nlm:aff></affiliation><affiliation><nlm:aff id="A26">Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, 75 M. Asias Street, Goudi, GR-115 27, Athens, Greece</nlm:aff></affiliation></author><author><name sortKey="Masala, Giovanna" sort="Masala, Giovanna" uniqKey="Masala G" first="Giovanna" last="Masala">Giovanna Masala</name><affiliation><nlm:aff id="A27">Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute – ISPO, Florence, Italy</nlm:aff></affiliation></author><author><name sortKey="Sieri, Sabina" sort="Sieri, Sabina" uniqKey="Sieri S" first="Sabina" last="Sieri">Sabina Sieri</name><affiliation><nlm:aff id="A28">Epidemiology and Prevention Unit, Fondazione IRCSS Istituto Nazionale dei Tumori, Milano, Italy</nlm:aff></affiliation></author><author><name sortKey="Tumino, Rosario" sort="Tumino, Rosario" uniqKey="Tumino R" first="Rosario" last="Tumino">Rosario Tumino</name><affiliation><nlm:aff id="A29">Cancer Registry and Histopathology Unit, “Civic - M.P. Arezzo” Hospital, ASP Ragusa, Italy</nlm:aff></affiliation></author><author><name sortKey="Vineis, Paolo" sort="Vineis, Paolo" uniqKey="Vineis P" first="Paolo" last="Vineis">Paolo Vineis</name><affiliation><nlm:aff id="A2">Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom</nlm:aff></affiliation><affiliation><nlm:aff id="A30">Human Genetics Foundation, Torino, Italy</nlm:aff></affiliation></author><author><name sortKey="Mattiello, Amalia" sort="Mattiello, Amalia" uniqKey="Mattiello A" first="Amalia" last="Mattiello">Amalia Mattiello</name><affiliation><nlm:aff id="A31">Dipartimento di Medicina Clinica e Chirurgia, Federico II University, Naples, Italy</nlm:aff></affiliation></author><author><name sortKey="Bueno De Mesquita, H B" sort="Bueno De Mesquita, H B" uniqKey="Bueno De Mesquita H" first="H. B." last="Bueno-De-Mesquita">H. B. Bueno-De-Mesquita</name><affiliation><nlm:aff id="A2">Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom</nlm:aff></affiliation><affiliation><nlm:aff id="A32">National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands</nlm:aff></affiliation><affiliation><nlm:aff id="A33">Department of Gastroenterology and Hepatology, University Medical Centre, Utrecht, The Netherlands</nlm:aff></affiliation><affiliation><nlm:aff id="A34">Department. of Social & Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia</nlm:aff></affiliation></author><author><name sortKey="Onland Moret, N Charlotte" sort="Onland Moret, N Charlotte" uniqKey="Onland Moret N" first="N. Charlotte" last="Onland-Moret">N. Charlotte Onland-Moret</name><affiliation><nlm:aff id="A3">Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Wirf Lt, Elisabeth" sort="Wirf Lt, Elisabeth" uniqKey="Wirf Lt E" first="Elisabeth" last="Wirf Lt">Elisabeth Wirf Lt</name><affiliation><nlm:aff id="A35">Department of Clinical Sciences, Nutrition Epidemiology, Lund University, Malmö, Sweden</nlm:aff></affiliation></author><author><name sortKey="Stocks, Tanja" sort="Stocks, Tanja" uniqKey="Stocks T" first="Tanja" last="Stocks">Tanja Stocks</name><affiliation><nlm:aff id="A35">Department of Clinical Sciences, Nutrition Epidemiology, Lund University, Malmö, Sweden</nlm:aff></affiliation><affiliation><nlm:aff id="A36">Umeå University, Department of Perioperative and Surgical Sciences, Sweden</nlm:aff></affiliation></author><author><name sortKey="Idahl, Annika" sort="Idahl, Annika" uniqKey="Idahl A" first="Annika" last="Idahl">Annika Idahl</name><affiliation><nlm:aff id="A37">Department of Clinical Sciences, Obstetrics and Gynecology and Department of Public Health and Clinical Medicine, Nutritional Research Umeå University, Umeå, Sweden</nlm:aff></affiliation></author><author><name sortKey="Lundin, Eva" sort="Lundin, Eva" uniqKey="Lundin E" first="Eva" last="Lundin">Eva Lundin</name><affiliation><nlm:aff id="A38">Department of Medical Biosciences, Pathology Umeå University, Umeå, Sweden</nlm:aff></affiliation></author><author><name sortKey="Skeie, Guri" sort="Skeie, Guri" uniqKey="Skeie G" first="Guri" last="Skeie">Guri Skeie</name><affiliation><nlm:aff id="A39">Department of Community Medicine, Faculty of Health Sciences, UiT The Artic University of Norway, N - 9037 Tromsø, Norway</nlm:aff></affiliation></author><author><name sortKey="Gram, Inger T" sort="Gram, Inger T" uniqKey="Gram I" first="Inger T." last="Gram">Inger T. Gram</name><affiliation><nlm:aff id="A39">Department of Community Medicine, Faculty of Health Sciences, UiT The Artic University of Norway, N - 9037 Tromsø, Norway</nlm:aff></affiliation></author><author><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name><affiliation><nlm:aff id="A39">Department of Community Medicine, Faculty of Health Sciences, UiT The Artic University of Norway, N - 9037 Tromsø, Norway</nlm:aff></affiliation><affiliation><nlm:aff id="A40">Cancer Registry of Norway, Oslo, Norway</nlm:aff></affiliation><affiliation><nlm:aff id="A41">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</nlm:aff></affiliation><affiliation><nlm:aff id="A42">Department of Genetic Epidemiology, Folkhälsan Research Center, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Riboli, Elio" sort="Riboli, Elio" uniqKey="Riboli E" first="Elio" last="Riboli">Elio Riboli</name><affiliation><nlm:aff id="A2">Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Duell, Eric J" sort="Duell, Eric J" uniqKey="Duell E" first="Eric J" last="Duell">Eric J. Duell</name><affiliation><nlm:aff id="A1">Unit of Nutrition, Environment and Cancer. Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO-IDIBELL), Barcelona, Spain</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">25300475</idno><idno type="pmc">4295892</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295892</idno><idno type="RBID">PMC:4295892</idno><idno type="doi">10.1158/1055-9965.EPI-14-0636</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">002094</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002094</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Dietary intake of acrylamide and epithelial ovarian cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort</title><author><name sortKey="Ob N Santacana, Mireia" sort="Ob N Santacana, Mireia" uniqKey="Ob N Santacana M" first="Mireia" last="Ob N-Santacana">Mireia Ob N-Santacana</name><affiliation><nlm:aff id="A1">Unit of Nutrition, Environment and Cancer. Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO-IDIBELL), Barcelona, Spain</nlm:aff></affiliation></author><author><name sortKey="Peeters, Petra H M" sort="Peeters, Petra H M" uniqKey="Peeters P" first="Petra H. M." last="Peeters">Petra H. M. Peeters</name><affiliation><nlm:aff id="A2">Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom</nlm:aff></affiliation><affiliation><nlm:aff id="A3">Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Freisling, Heinz" sort="Freisling, Heinz" uniqKey="Freisling H" first="Heinz" last="Freisling">Heinz Freisling</name><affiliation><nlm:aff id="A4">Dietary Exposure Assessment Group, International Agency for Research on Cancer, 150 Cours Albert Thomas, Lyon 69372, France Lyon, France.</nlm:aff></affiliation></author><author><name sortKey="Dossus, Laure" sort="Dossus, Laure" uniqKey="Dossus L" first="Laure" last="Dossus">Laure Dossus</name><affiliation><nlm:aff id="A5">Inserm, Centre for research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women’s Health team, F-94805, Villejuif, France</nlm:aff></affiliation><affiliation><nlm:aff id="A6">Univ Paris Sud, UMRS 1018, F-94805, Villejuif, France</nlm:aff></affiliation><affiliation><nlm:aff id="A7">IGR, F-94805, Villejuif, France</nlm:aff></affiliation></author><author><name sortKey="Clavel Chapelon, Francoise" sort="Clavel Chapelon, Francoise" uniqKey="Clavel Chapelon F" first="Françoise" last="Clavel-Chapelon">Françoise Clavel-Chapelon</name><affiliation><nlm:aff id="A5">Inserm, Centre for research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women’s Health team, F-94805, Villejuif, France</nlm:aff></affiliation><affiliation><nlm:aff id="A6">Univ Paris Sud, UMRS 1018, F-94805, Villejuif, France</nlm:aff></affiliation><affiliation><nlm:aff id="A7">IGR, F-94805, Villejuif, France</nlm:aff></affiliation></author><author><name sortKey="Baglietto, Laura" sort="Baglietto, Laura" uniqKey="Baglietto L" first="Laura" last="Baglietto">Laura Baglietto</name><affiliation><nlm:aff id="A8">Cancer Epidemiology Centre, Cancer Council of Victoria, Melbourne, Australia.</nlm:aff></affiliation><affiliation><nlm:aff id="A9">Centre for Epidemiology and Biostatistics, School of Population and Global Health, University of Melbourne, Australia.</nlm:aff></affiliation></author><author><name sortKey="Schock, Helena" sort="Schock, Helena" uniqKey="Schock H" first="Helena" last="Schock">Helena Schock</name><affiliation><nlm:aff id="A10">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Fortner, Renee T" sort="Fortner, Renee T" uniqKey="Fortner R" first="Renée T." last="Fortner">Renée T. Fortner</name><affiliation><nlm:aff id="A10">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Boeing, Heiner" sort="Boeing, Heiner" uniqKey="Boeing H" first="Heiner" last="Boeing">Heiner Boeing</name><affiliation><nlm:aff id="A11">Department of Epidemiology, German Institute of Human Nutrition, Potsdam-Rehbruecke, Nuthetal, Germany</nlm:aff></affiliation></author><author><name sortKey="Tj Nneland, Anne" sort="Tj Nneland, Anne" uniqKey="Tj Nneland A" first="Anne" last="Tj Nneland">Anne Tj Nneland</name><affiliation><nlm:aff id="A12">Danish Cancer Society Research Center, Copenhagen, Denmark</nlm:aff></affiliation></author><author><name sortKey="Olsen, Anja" sort="Olsen, Anja" uniqKey="Olsen A" first="Anja" last="Olsen">Anja Olsen</name><affiliation><nlm:aff id="A12">Danish Cancer Society Research Center, Copenhagen, Denmark</nlm:aff></affiliation></author><author><name sortKey="Overvad, Kim" sort="Overvad, Kim" uniqKey="Overvad K" first="Kim" last="Overvad">Kim Overvad</name><affiliation><nlm:aff id="A13">Department of Public Health, Section for Epidemiology, Aarhus University, Aarhus, Denmark</nlm:aff></affiliation></author><author><name sortKey="Menendez, Virginia" sort="Menendez, Virginia" uniqKey="Menendez V" first="Virginia" last="Menéndez">Virginia Menéndez</name><affiliation><nlm:aff id="A14">Public Health Directorate, Asturias, Spain</nlm:aff></affiliation></author><author><name sortKey="Sanchez, Maria Jose" sort="Sanchez, Maria Jose" uniqKey="Sanchez M" first="Maria-José" last="Sanchez">Maria-José Sanchez</name><affiliation><nlm:aff id="A15">Escuela Andaluza de Salud Pública. Instituto de Investigación Biosanitaria de Granada (Granada.ibs), Granada (Spain)</nlm:aff></affiliation><affiliation><nlm:aff id="A16">Consortium for Biomedical Research in Epidemiology and Public Health (CIBER Epidemiología y Salud Pública-CIBERESP), Madrid, Spain</nlm:aff></affiliation></author><author><name sortKey="Larra Aga, Nerea" sort="Larra Aga, Nerea" uniqKey="Larra Aga N" first="Nerea" last="Larra Aga">Nerea Larra Aga</name><affiliation><nlm:aff id="A16">Consortium for Biomedical Research in Epidemiology and Public Health (CIBER Epidemiología y Salud Pública-CIBERESP), Madrid, Spain</nlm:aff></affiliation><affiliation><nlm:aff id="A17">Public Health Division of Gipuzkoa-BIODONOSTIA, Basque Regional Health Department, Spain</nlm:aff></affiliation></author><author><name sortKey="Casta O, Jose Maria Huerta" sort="Casta O, Jose Maria Huerta" uniqKey="Casta O J" first="José María Huerta" last="Casta O">José María Huerta Casta O</name><affiliation><nlm:aff id="A16">Consortium for Biomedical Research in Epidemiology and Public Health (CIBER Epidemiología y Salud Pública-CIBERESP), Madrid, Spain</nlm:aff></affiliation><affiliation><nlm:aff id="A18">Department of Epidemiology, Murcia Regional Health Council, Murcia, Spain</nlm:aff></affiliation></author><author><name sortKey="Barricarte, Aurelio" sort="Barricarte, Aurelio" uniqKey="Barricarte A" first="Aurelio" last="Barricarte">Aurelio Barricarte</name><affiliation><nlm:aff id="A16">Consortium for Biomedical Research in Epidemiology and Public Health (CIBER Epidemiología y Salud Pública-CIBERESP), Madrid, Spain</nlm:aff></affiliation><affiliation><nlm:aff id="A19">Navarre Public Health Institute, Pamplona, Spain</nlm:aff></affiliation></author><author><name sortKey="Khaw, Kay Tee" sort="Khaw, Kay Tee" uniqKey="Khaw K" first="Kay-Tee" last="Khaw">Kay-Tee Khaw</name><affiliation><nlm:aff id="A20">University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Wareham, Nick" sort="Wareham, Nick" uniqKey="Wareham N" first="Nick" last="Wareham">Nick Wareham</name><affiliation><nlm:aff id="A21">MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Travis, Ruth C" sort="Travis, Ruth C" uniqKey="Travis R" first="Ruth C." last="Travis">Ruth C. Travis</name><affiliation><nlm:aff id="A22">Cancer Epidemiology Unit, Nuffield Department of Population Health University of Oxford, Oxford, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Merritt, Melissa A" sort="Merritt, Melissa A" uniqKey="Merritt M" first="Melissa A." last="Merritt">Melissa A. Merritt</name><affiliation><nlm:aff id="A2">Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Trichopoulou, Antonia" sort="Trichopoulou, Antonia" uniqKey="Trichopoulou A" first="Antonia" last="Trichopoulou">Antonia Trichopoulou</name><affiliation><nlm:aff id="A23">Hellenic Health Foundation, 13 Kaisareias Street, Athens, GR-115 27, Greece</nlm:aff></affiliation><affiliation><nlm:aff id="A24">Bureau of Epidemiologic Research, Academy of Athens, 23 Alexandroupoleos Street, Athens, GR-115 27, Greece</nlm:aff></affiliation></author><author><name sortKey="Trichopoulos, Dimitrios" sort="Trichopoulos, Dimitrios" uniqKey="Trichopoulos D" first="Dimitrios" last="Trichopoulos">Dimitrios Trichopoulos</name><affiliation><nlm:aff id="A23">Hellenic Health Foundation, 13 Kaisareias Street, Athens, GR-115 27, Greece</nlm:aff></affiliation><affiliation><nlm:aff id="A24">Bureau of Epidemiologic Research, Academy of Athens, 23 Alexandroupoleos Street, Athens, GR-115 27, Greece</nlm:aff></affiliation><affiliation><nlm:aff id="A25">Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA</nlm:aff></affiliation></author><author><name sortKey="Orfanos, Philippos" sort="Orfanos, Philippos" uniqKey="Orfanos P" first="Philippos" last="Orfanos">Philippos Orfanos</name><affiliation><nlm:aff id="A23">Hellenic Health Foundation, 13 Kaisareias Street, Athens, GR-115 27, Greece</nlm:aff></affiliation><affiliation><nlm:aff id="A26">Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, 75 M. Asias Street, Goudi, GR-115 27, Athens, Greece</nlm:aff></affiliation></author><author><name sortKey="Masala, Giovanna" sort="Masala, Giovanna" uniqKey="Masala G" first="Giovanna" last="Masala">Giovanna Masala</name><affiliation><nlm:aff id="A27">Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute – ISPO, Florence, Italy</nlm:aff></affiliation></author><author><name sortKey="Sieri, Sabina" sort="Sieri, Sabina" uniqKey="Sieri S" first="Sabina" last="Sieri">Sabina Sieri</name><affiliation><nlm:aff id="A28">Epidemiology and Prevention Unit, Fondazione IRCSS Istituto Nazionale dei Tumori, Milano, Italy</nlm:aff></affiliation></author><author><name sortKey="Tumino, Rosario" sort="Tumino, Rosario" uniqKey="Tumino R" first="Rosario" last="Tumino">Rosario Tumino</name><affiliation><nlm:aff id="A29">Cancer Registry and Histopathology Unit, “Civic - M.P. Arezzo” Hospital, ASP Ragusa, Italy</nlm:aff></affiliation></author><author><name sortKey="Vineis, Paolo" sort="Vineis, Paolo" uniqKey="Vineis P" first="Paolo" last="Vineis">Paolo Vineis</name><affiliation><nlm:aff id="A2">Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom</nlm:aff></affiliation><affiliation><nlm:aff id="A30">Human Genetics Foundation, Torino, Italy</nlm:aff></affiliation></author><author><name sortKey="Mattiello, Amalia" sort="Mattiello, Amalia" uniqKey="Mattiello A" first="Amalia" last="Mattiello">Amalia Mattiello</name><affiliation><nlm:aff id="A31">Dipartimento di Medicina Clinica e Chirurgia, Federico II University, Naples, Italy</nlm:aff></affiliation></author><author><name sortKey="Bueno De Mesquita, H B" sort="Bueno De Mesquita, H B" uniqKey="Bueno De Mesquita H" first="H. B." last="Bueno-De-Mesquita">H. B. Bueno-De-Mesquita</name><affiliation><nlm:aff id="A2">Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom</nlm:aff></affiliation><affiliation><nlm:aff id="A32">National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands</nlm:aff></affiliation><affiliation><nlm:aff id="A33">Department of Gastroenterology and Hepatology, University Medical Centre, Utrecht, The Netherlands</nlm:aff></affiliation><affiliation><nlm:aff id="A34">Department. of Social & Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia</nlm:aff></affiliation></author><author><name sortKey="Onland Moret, N Charlotte" sort="Onland Moret, N Charlotte" uniqKey="Onland Moret N" first="N. Charlotte" last="Onland-Moret">N. Charlotte Onland-Moret</name><affiliation><nlm:aff id="A3">Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Wirf Lt, Elisabeth" sort="Wirf Lt, Elisabeth" uniqKey="Wirf Lt E" first="Elisabeth" last="Wirf Lt">Elisabeth Wirf Lt</name><affiliation><nlm:aff id="A35">Department of Clinical Sciences, Nutrition Epidemiology, Lund University, Malmö, Sweden</nlm:aff></affiliation></author><author><name sortKey="Stocks, Tanja" sort="Stocks, Tanja" uniqKey="Stocks T" first="Tanja" last="Stocks">Tanja Stocks</name><affiliation><nlm:aff id="A35">Department of Clinical Sciences, Nutrition Epidemiology, Lund University, Malmö, Sweden</nlm:aff></affiliation><affiliation><nlm:aff id="A36">Umeå University, Department of Perioperative and Surgical Sciences, Sweden</nlm:aff></affiliation></author><author><name sortKey="Idahl, Annika" sort="Idahl, Annika" uniqKey="Idahl A" first="Annika" last="Idahl">Annika Idahl</name><affiliation><nlm:aff id="A37">Department of Clinical Sciences, Obstetrics and Gynecology and Department of Public Health and Clinical Medicine, Nutritional Research Umeå University, Umeå, Sweden</nlm:aff></affiliation></author><author><name sortKey="Lundin, Eva" sort="Lundin, Eva" uniqKey="Lundin E" first="Eva" last="Lundin">Eva Lundin</name><affiliation><nlm:aff id="A38">Department of Medical Biosciences, Pathology Umeå University, Umeå, Sweden</nlm:aff></affiliation></author><author><name sortKey="Skeie, Guri" sort="Skeie, Guri" uniqKey="Skeie G" first="Guri" last="Skeie">Guri Skeie</name><affiliation><nlm:aff id="A39">Department of Community Medicine, Faculty of Health Sciences, UiT The Artic University of Norway, N - 9037 Tromsø, Norway</nlm:aff></affiliation></author><author><name sortKey="Gram, Inger T" sort="Gram, Inger T" uniqKey="Gram I" first="Inger T." last="Gram">Inger T. Gram</name><affiliation><nlm:aff id="A39">Department of Community Medicine, Faculty of Health Sciences, UiT The Artic University of Norway, N - 9037 Tromsø, Norway</nlm:aff></affiliation></author><author><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name><affiliation><nlm:aff id="A39">Department of Community Medicine, Faculty of Health Sciences, UiT The Artic University of Norway, N - 9037 Tromsø, Norway</nlm:aff></affiliation><affiliation><nlm:aff id="A40">Cancer Registry of Norway, Oslo, Norway</nlm:aff></affiliation><affiliation><nlm:aff id="A41">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</nlm:aff></affiliation><affiliation><nlm:aff id="A42">Department of Genetic Epidemiology, Folkhälsan Research Center, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Riboli, Elio" sort="Riboli, Elio" uniqKey="Riboli E" first="Elio" last="Riboli">Elio Riboli</name><affiliation><nlm:aff id="A2">Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Duell, Eric J" sort="Duell, Eric J" uniqKey="Duell E" first="Eric J" last="Duell">Eric J. Duell</name><affiliation><nlm:aff id="A1">Unit of Nutrition, Environment and Cancer. Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO-IDIBELL), Barcelona, Spain</nlm:aff></affiliation></author></analytic><series><title level="j">Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology</title><idno type="ISSN">1055-9965</idno><idno type="eISSN">1538-7755</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">Acrylamide, classified in 1994 by IARC as ‘probably carcinogenic’ to humans, was discovered in 2002 in some heat-treated, carbohydrate-rich foods. The association between dietary acrylamide intake and epithelial ovarian cancer risk (EOC) has been previously studied in one case-control and three prospective cohort studies which obtained inconsistent results, and could not further examine histological subtypes other than serous EOC. The present study was carried out in the European Prospective Investigation into Cancer and Nutrition (EPIC) sub-cohort of women (<italic>n</italic>=325,006). Multivariate Cox proportional hazards models were used to assess the association between questionnaire-based acrylamide intake and EOC risk. Acrylamide was energy-adjusted using the residual method, and was evaluated both as a continuous variable (per 10μg/day) and in quintiles; when subgroups by histological EOC subtypes were analyzed, acrylamide intake was evaluated in quartiles. During a mean follow-up of 11 years, 1,191 incident EOC cases were diagnosed. At baseline, the median acrylamide intake in EPIC was 21.3 μg/day. No associations, and no evidence for a dose-response were observed between energy-adjusted acrylamide intake and EOC risk (HR<sub>10μg/day</sub>:1.02, 95%CI:0.96-1.09; HR<sub>Q5vsQ1</sub>:0.97, 95%CI:0.76-1.23). No differences were seen when invasive EOC subtypes (582 serous, 118 endometrioid, and 79 mucinous tumors) were analyzed separately. This study did not provide evidence that acrylamide intake, based on food intake questionnaires, was associated with risk for EOC in EPIC. Additional studies with more reliable estimates of exposure based on biomarkers may be needed.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">9200608</journal-id><journal-id journal-id-type="pubmed-jr-id">2299</journal-id><journal-id journal-id-type="nlm-ta">Cancer Epidemiol Biomarkers Prev</journal-id><journal-id journal-id-type="iso-abbrev">Cancer Epidemiol. Biomarkers Prev.</journal-id><journal-title-group><journal-title>Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology</journal-title></journal-title-group><issn pub-type="ppub">1055-9965</issn><issn pub-type="epub">1538-7755</issn></journal-meta><article-meta><article-id pub-id-type="pmid">25300475</article-id><article-id pub-id-type="pmc">4295892</article-id><article-id pub-id-type="doi">10.1158/1055-9965.EPI-14-0636</article-id><article-id pub-id-type="manuscript">EMS60655</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Dietary intake of acrylamide and epithelial ovarian cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Obón-Santacana</surname><given-names>Mireia</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Peeters</surname><given-names>Petra H.M.</given-names></name><xref ref-type="aff" rid="A2">2</xref><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Freisling</surname><given-names>Heinz</given-names></name><xref ref-type="aff" rid="A4">4</xref></contrib><contrib contrib-type="author"><name><surname>Dossus</surname><given-names>Laure</given-names></name><xref ref-type="aff" rid="A5">5</xref><xref ref-type="aff" rid="A6">6</xref><xref ref-type="aff" rid="A7">7</xref></contrib><contrib contrib-type="author"><name><surname>Clavel-Chapelon</surname><given-names>Françoise</given-names></name><xref ref-type="aff" rid="A5">5</xref><xref ref-type="aff" rid="A6">6</xref><xref ref-type="aff" rid="A7">7</xref></contrib><contrib contrib-type="author"><name><surname>Baglietto</surname><given-names>Laura</given-names></name><xref ref-type="aff" rid="A8">8</xref><xref ref-type="aff" rid="A9">9</xref></contrib><contrib contrib-type="author"><name><surname>Schock</surname><given-names>Helena</given-names></name><xref ref-type="aff" rid="A10">10</xref></contrib><contrib contrib-type="author"><name><surname>Fortner</surname><given-names>Renée T.</given-names></name><xref ref-type="aff" rid="A10">10</xref></contrib><contrib contrib-type="author"><name><surname>Boeing</surname><given-names>Heiner</given-names></name><xref ref-type="aff" rid="A11">11</xref></contrib><contrib contrib-type="author"><name><surname>Tjønneland</surname><given-names>Anne</given-names></name><xref ref-type="aff" rid="A12">12</xref></contrib><contrib contrib-type="author"><name><surname>Olsen</surname><given-names>Anja</given-names></name><xref ref-type="aff" rid="A12">12</xref></contrib><contrib contrib-type="author"><name><surname>Overvad</surname><given-names>Kim</given-names></name><xref ref-type="aff" rid="A13">13</xref></contrib><contrib contrib-type="author"><name><surname>Menéndez</surname><given-names>Virginia</given-names></name><xref ref-type="aff" rid="A14">14</xref></contrib><contrib contrib-type="author"><name><surname>Sanchez</surname><given-names>Maria-José</given-names></name><xref ref-type="aff" rid="A15">15</xref><xref ref-type="aff" rid="A16">16</xref></contrib><contrib contrib-type="author"><name><surname>Larrañaga</surname><given-names>Nerea</given-names></name><xref ref-type="aff" rid="A16">16</xref><xref ref-type="aff" rid="A17">17</xref></contrib><contrib contrib-type="author"><name><surname>Castaño</surname><given-names>José María Huerta</given-names></name><xref ref-type="aff" rid="A16">16</xref><xref ref-type="aff" rid="A18">18</xref></contrib><contrib contrib-type="author"><name><surname>Barricarte</surname><given-names>Aurelio</given-names></name><xref ref-type="aff" rid="A16">16</xref><xref ref-type="aff" rid="A19">19</xref></contrib><contrib contrib-type="author"><name><surname>Khaw</surname><given-names>Kay-Tee</given-names></name><xref ref-type="aff" rid="A20">20</xref></contrib><contrib contrib-type="author"><name><surname>Wareham</surname><given-names>Nick</given-names></name><xref ref-type="aff" rid="A21">21</xref></contrib><contrib contrib-type="author"><name><surname>Travis</surname><given-names>Ruth C.</given-names></name><xref ref-type="aff" rid="A22">22</xref></contrib><contrib contrib-type="author"><name><surname>Merritt</surname><given-names>Melissa A.</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Trichopoulou</surname><given-names>Antonia</given-names></name><xref ref-type="aff" rid="A23">23</xref><xref ref-type="aff" rid="A24">24</xref></contrib><contrib contrib-type="author"><name><surname>Trichopoulos</surname><given-names>Dimitrios</given-names></name><xref ref-type="aff" rid="A23">23</xref><xref ref-type="aff" rid="A24">24</xref><xref ref-type="aff" rid="A25">25</xref></contrib><contrib contrib-type="author"><name><surname>Orfanos</surname><given-names>Philippos</given-names></name><xref ref-type="aff" rid="A23">23</xref><xref ref-type="aff" rid="A26">26</xref></contrib><contrib contrib-type="author"><name><surname>Masala</surname><given-names>Giovanna</given-names></name><xref ref-type="aff" rid="A27">27</xref></contrib><contrib contrib-type="author"><name><surname>Sieri</surname><given-names>Sabina</given-names></name><xref ref-type="aff" rid="A28">28</xref></contrib><contrib contrib-type="author"><name><surname>Tumino</surname><given-names>Rosario</given-names></name><xref ref-type="aff" rid="A29">29</xref></contrib><contrib contrib-type="author"><name><surname>Vineis</surname><given-names>Paolo</given-names></name><xref ref-type="aff" rid="A2">2</xref><xref ref-type="aff" rid="A30">30</xref></contrib><contrib contrib-type="author"><name><surname>Mattiello</surname><given-names>Amalia</given-names></name><xref ref-type="aff" rid="A31">31</xref></contrib><contrib contrib-type="author"><name><surname>Bueno-de-Mesquita</surname><given-names>H.B.</given-names></name><xref ref-type="aff" rid="A2">2</xref><xref ref-type="aff" rid="A32">32</xref><xref ref-type="aff" rid="A33">33</xref><xref ref-type="aff" rid="A34">34</xref></contrib><contrib contrib-type="author"><name><surname>Onland-Moret</surname><given-names>N. Charlotte</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Wirfält</surname><given-names>Elisabeth</given-names></name><xref ref-type="aff" rid="A35">35</xref></contrib><contrib contrib-type="author"><name><surname>Stocks</surname><given-names>Tanja</given-names></name><xref ref-type="aff" rid="A35">35</xref><xref ref-type="aff" rid="A36">36</xref></contrib><contrib contrib-type="author"><name><surname>Idahl</surname><given-names>Annika</given-names></name><xref ref-type="aff" rid="A37">37</xref></contrib><contrib contrib-type="author"><name><surname>Lundin</surname><given-names>Eva</given-names></name><xref ref-type="aff" rid="A38">38</xref></contrib><contrib contrib-type="author"><name><surname>Skeie</surname><given-names>Guri</given-names></name><xref ref-type="aff" rid="A39">39</xref></contrib><contrib contrib-type="author"><name><surname>Gram</surname><given-names>Inger T.</given-names></name><xref ref-type="aff" rid="A39">39</xref></contrib><contrib contrib-type="author"><name><surname>Weiderpass</surname><given-names>Elisabete</given-names></name><xref ref-type="aff" rid="A39">39</xref><xref ref-type="aff" rid="A40">40</xref><xref ref-type="aff" rid="A41">41</xref><xref ref-type="aff" rid="A42">42</xref></contrib><contrib contrib-type="author"><name><surname>Riboli</surname><given-names>Elio</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Duell</surname><given-names>Eric J</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib></contrib-group><aff id="A1"><label>1</label>Unit of Nutrition, Environment and Cancer. Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO-IDIBELL), Barcelona, Spain</aff><aff id="A2"><label>2</label>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom</aff><aff id="A3"><label>3</label>Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, The Netherlands</aff><aff id="A4"><label>4</label>Dietary Exposure Assessment Group, International Agency for Research on Cancer, 150 Cours Albert Thomas, Lyon 69372, France Lyon, France.</aff><aff id="A5"><label>5</label>Inserm, Centre for research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women’s Health team, F-94805, Villejuif, France</aff><aff id="A6"><label>6</label>Univ Paris Sud, UMRS 1018, F-94805, Villejuif, France</aff><aff id="A7"><label>7</label>IGR, F-94805, Villejuif, France</aff><aff id="A8"><label>8</label>Cancer Epidemiology Centre, Cancer Council of Victoria, Melbourne, Australia.</aff><aff id="A9"><label>9</label>Centre for Epidemiology and Biostatistics, School of Population and Global Health, University of Melbourne, Australia.</aff><aff id="A10"><label>10</label>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</aff><aff id="A11"><label>11</label>Department of Epidemiology, German Institute of Human Nutrition, Potsdam-Rehbruecke, Nuthetal, Germany</aff><aff id="A12"><label>12</label>Danish Cancer Society Research Center, Copenhagen, Denmark</aff><aff id="A13"><label>13</label>Department of Public Health, Section for Epidemiology, Aarhus University, Aarhus, Denmark</aff><aff id="A14"><label>14</label>Public Health Directorate, Asturias, Spain</aff><aff id="A15"><label>15</label>Escuela Andaluza de Salud Pública. Instituto de Investigación Biosanitaria de Granada (Granada.ibs), Granada (Spain)</aff><aff id="A16"><label>16</label>Consortium for Biomedical Research in Epidemiology and Public Health (CIBER Epidemiología y Salud Pública-CIBERESP), Madrid, Spain</aff><aff id="A17"><label>17</label>Public Health Division of Gipuzkoa-BIODONOSTIA, Basque Regional Health Department, Spain</aff><aff id="A18"><label>18</label>Department of Epidemiology, Murcia Regional Health Council, Murcia, Spain</aff><aff id="A19"><label>19</label>Navarre Public Health Institute, Pamplona, Spain</aff><aff id="A20"><label>20</label>University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom</aff><aff id="A21"><label>21</label>MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom</aff><aff id="A22"><label>22</label>Cancer Epidemiology Unit, Nuffield Department of Population Health University of Oxford, Oxford, United Kingdom</aff><aff id="A23"><label>23</label>Hellenic Health Foundation, 13 Kaisareias Street, Athens, GR-115 27, Greece</aff><aff id="A24"><label>24</label>Bureau of Epidemiologic Research, Academy of Athens, 23 Alexandroupoleos Street, Athens, GR-115 27, Greece</aff><aff id="A25"><label>25</label>Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA</aff><aff id="A26"><label>26</label>Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, 75 M. Asias Street, Goudi, GR-115 27, Athens, Greece</aff><aff id="A27"><label>27</label>Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute – ISPO, Florence, Italy</aff><aff id="A28"><label>28</label>Epidemiology and Prevention Unit, Fondazione IRCSS Istituto Nazionale dei Tumori, Milano, Italy</aff><aff id="A29"><label>29</label>Cancer Registry and Histopathology Unit, “Civic - M.P. Arezzo” Hospital, ASP Ragusa, Italy</aff><aff id="A30"><label>30</label>Human Genetics Foundation, Torino, Italy</aff><aff id="A31"><label>31</label>Dipartimento di Medicina Clinica e Chirurgia, Federico II University, Naples, Italy</aff><aff id="A32"><label>32</label>National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands</aff><aff id="A33"><label>33</label>Department of Gastroenterology and Hepatology, University Medical Centre, Utrecht, The Netherlands</aff><aff id="A34"><label>34</label>Department. of Social & Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia</aff><aff id="A35"><label>35</label>Department of Clinical Sciences, Nutrition Epidemiology, Lund University, Malmö, Sweden</aff><aff id="A36"><label>36</label>Umeå University, Department of Perioperative and Surgical Sciences, Sweden</aff><aff id="A37"><label>37</label>Department of Clinical Sciences, Obstetrics and Gynecology and Department of Public Health and Clinical Medicine, Nutritional Research Umeå University, Umeå, Sweden</aff><aff id="A38"><label>38</label>Department of Medical Biosciences, Pathology Umeå University, Umeå, Sweden</aff><aff id="A39"><label>39</label>Department of Community Medicine, Faculty of Health Sciences, UiT The Artic University of Norway, N - 9037 Tromsø, Norway</aff><aff id="A40"><label>40</label>Cancer Registry of Norway, Oslo, Norway</aff><aff id="A41"><label>41</label>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</aff><aff id="A42"><label>42</label>Department of Genetic Epidemiology, Folkhälsan Research Center, Helsinki, Finland</aff><author-notes><corresp id="CR1"><bold><underline>Correspondence to:</underline></bold> Eric J. Duell, Unit of Nutrition, Environment and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology, Avda Gran Via 199-203, 08907 L’Hospitalet del Llobregat, Barcelona, Spain. Phone: +34 93 260 7401; Fax: +34 93 260 7787. <email>eduell@iconcologia.net</email></corresp></author-notes><pub-date pub-type="nihms-submitted"><day>20</day><month>10</month><year>2014</year></pub-date><pub-date pub-type="epub"><day>09</day><month>10</month><year>2014</year></pub-date><pub-date pub-type="ppub"><month>1</month><year>2015</year></pub-date><pub-date pub-type="pmc-release"><day>01</day><month>7</month><year>2015</year></pub-date><volume>24</volume><issue>1</issue><fpage>291</fpage><lpage>297</lpage><pmc-comment>elocation-id from pubmed: 10.1158/1055-9965.EPI-14-0636</pmc-comment>
<abstract><p id="P1">Acrylamide, classified in 1994 by IARC as ‘probably carcinogenic’ to humans, was discovered in 2002 in some heat-treated, carbohydrate-rich foods. The association between dietary acrylamide intake and epithelial ovarian cancer risk (EOC) has been previously studied in one case-control and three prospective cohort studies which obtained inconsistent results, and could not further examine histological subtypes other than serous EOC. The present study was carried out in the European Prospective Investigation into Cancer and Nutrition (EPIC) sub-cohort of women (<italic>n</italic>=325,006). Multivariate Cox proportional hazards models were used to assess the association between questionnaire-based acrylamide intake and EOC risk. Acrylamide was energy-adjusted using the residual method, and was evaluated both as a continuous variable (per 10μg/day) and in quintiles; when subgroups by histological EOC subtypes were analyzed, acrylamide intake was evaluated in quartiles. During a mean follow-up of 11 years, 1,191 incident EOC cases were diagnosed. At baseline, the median acrylamide intake in EPIC was 21.3 μg/day. No associations, and no evidence for a dose-response were observed between energy-adjusted acrylamide intake and EOC risk (HR<sub>10μg/day</sub>:1.02, 95%CI:0.96-1.09; HR<sub>Q5vsQ1</sub>:0.97, 95%CI:0.76-1.23). No differences were seen when invasive EOC subtypes (582 serous, 118 endometrioid, and 79 mucinous tumors) were analyzed separately. This study did not provide evidence that acrylamide intake, based on food intake questionnaires, was associated with risk for EOC in EPIC. Additional studies with more reliable estimates of exposure based on biomarkers may be needed.</p></abstract><kwd-group><kwd>acrylamide</kwd><kwd>epithelial ovarian cancer</kwd><kwd>cohort</kwd><kwd>nutrition</kwd><kwd>EPIC</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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