Links to Exploration step
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Genome-wide association study of colorectal cancer identifies six new susceptibility loci</title><author><name sortKey="Schumacher, Fredrick R" sort="Schumacher, Fredrick R" uniqKey="Schumacher F" first="Fredrick R." last="Schumacher">Fredrick R. Schumacher</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Schmit, Stephanie L" sort="Schmit, Stephanie L" uniqKey="Schmit S" first="Stephanie L." last="Schmit">Stephanie L. Schmit</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A2">Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Jiao, Shuo" sort="Jiao, Shuo" uniqKey="Jiao S" first="Shuo" last="Jiao">Shuo Jiao</name><affiliation><nlm:aff id="A3">Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98124, USA</nlm:aff></affiliation></author><author><name sortKey="Edlund, Christopher K" sort="Edlund, Christopher K" uniqKey="Edlund C" first="Christopher K." last="Edlund">Christopher K. Edlund</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Wang, Hansong" sort="Wang, Hansong" uniqKey="Wang H" first="Hansong" last="Wang">Hansong Wang</name><affiliation><nlm:aff id="A4">Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96822, USA</nlm:aff></affiliation></author><author><name sortKey="Zhang, Ben" sort="Zhang, Ben" uniqKey="Zhang B" first="Ben" last="Zhang">Ben Zhang</name><affiliation><nlm:aff id="A5">Department of General Surgery, Third Military Medical University Southwest Hospital, Chongqing 400038, China</nlm:aff></affiliation></author><author><name sortKey="Hsu, Li" sort="Hsu, Li" uniqKey="Hsu L" first="Li" last="Hsu">Li Hsu</name><affiliation><nlm:aff id="A3">Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98124, USA</nlm:aff></affiliation></author><author><name sortKey="Huang, Shu Chen" sort="Huang, Shu Chen" uniqKey="Huang S" first="Shu-Chen" last="Huang">Shu-Chen Huang</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Fischer, Christopher P" sort="Fischer, Christopher P" uniqKey="Fischer C" first="Christopher P." last="Fischer">Christopher P. Fischer</name><affiliation><nlm:aff id="A6">University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan 48105, USA</nlm:aff></affiliation></author><author><name sortKey="Harju, John F" sort="Harju, John F" uniqKey="Harju J" first="John F." last="Harju">John F. Harju</name><affiliation><nlm:aff id="A6">University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan 48105, USA</nlm:aff></affiliation></author><author><name sortKey="Idos, Gregory E" sort="Idos, Gregory E" uniqKey="Idos G" first="Gregory E." last="Idos">Gregory E. Idos</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Lejbkowicz, Flavio" sort="Lejbkowicz, Flavio" uniqKey="Lejbkowicz F" first="Flavio" last="Lejbkowicz">Flavio Lejbkowicz</name><affiliation><nlm:aff id="A7">Department of Community Medicine and Epidemiology, Carmel Medical Center, Haifa 34361, Israel</nlm:aff></affiliation><affiliation><nlm:aff id="A8">Clalit Health Services National Cancer Control Center, Haifa 34361, Israel</nlm:aff></affiliation></author><author><name sortKey="Manion, Frank J" sort="Manion, Frank J" uniqKey="Manion F" first="Frank J." last="Manion">Frank J. Manion</name><affiliation><nlm:aff id="A6">University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan 48105, USA</nlm:aff></affiliation></author><author><name sortKey="Mcdonnell, Kevin" sort="Mcdonnell, Kevin" uniqKey="Mcdonnell K" first="Kevin" last="Mcdonnell">Kevin Mcdonnell</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Mcneil, Caroline E" sort="Mcneil, Caroline E" uniqKey="Mcneil C" first="Caroline E." last="Mcneil">Caroline E. Mcneil</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Melas, Marilena" sort="Melas, Marilena" uniqKey="Melas M" first="Marilena" last="Melas">Marilena Melas</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Rennert, Hedy S" sort="Rennert, Hedy S" uniqKey="Rennert H" first="Hedy S." last="Rennert">Hedy S. Rennert</name><affiliation><nlm:aff id="A7">Department of Community Medicine and Epidemiology, Carmel Medical Center, Haifa 34361, Israel</nlm:aff></affiliation><affiliation><nlm:aff id="A8">Clalit Health Services National Cancer Control Center, Haifa 34361, Israel</nlm:aff></affiliation></author><author><name sortKey="Shi, Wei" sort="Shi, Wei" uniqKey="Shi W" first="Wei" last="Shi">Wei Shi</name><affiliation><nlm:aff id="A9">Department of Surgery, Children’s Hospital Los Angeles, Los Angeles, California 90027, USA</nlm:aff></affiliation></author><author><name sortKey="Thomas, Duncan C" sort="Thomas, Duncan C" uniqKey="Thomas D" first="Duncan C." last="Thomas">Duncan C. Thomas</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Van Den Berg, David J" sort="Van Den Berg, David J" uniqKey="Van Den Berg D" first="David J." last="Van Den Berg">David J. Van Den Berg</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Hutter, Carolyn M" sort="Hutter, Carolyn M" uniqKey="Hutter C" first="Carolyn M." last="Hutter">Carolyn M. Hutter</name><affiliation><nlm:aff id="A10">Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20892, USA</nlm:aff></affiliation></author><author><name sortKey="Aragaki, Aaron K" sort="Aragaki, Aaron K" uniqKey="Aragaki A" first="Aaron K." last="Aragaki">Aaron K. Aragaki</name><affiliation><nlm:aff id="A3">Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98124, USA</nlm:aff></affiliation></author><author><name sortKey="Butterbach, Katja" sort="Butterbach, Katja" uniqKey="Butterbach K" first="Katja" last="Butterbach">Katja Butterbach</name><affiliation><nlm:aff id="A11">Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg 69121, Germany</nlm:aff></affiliation></author><author><name sortKey="Caan, Bette J" sort="Caan, Bette J" uniqKey="Caan B" first="Bette J." last="Caan">Bette J. Caan</name><affiliation><nlm:aff id="A12">Division of Research, Kaiser Permanente Medical Care Program of Northern California, Oakland, California 94612, USA</nlm:aff></affiliation></author><author><name sortKey="Carlson, Christopher S" sort="Carlson, Christopher S" uniqKey="Carlson C" first="Christopher S." last="Carlson">Christopher S. Carlson</name><affiliation><nlm:aff id="A3">Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98124, USA</nlm:aff></affiliation></author><author><name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J." last="Chanock">Stephen J. Chanock</name><affiliation><nlm:aff id="A13">Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892-9776, USA</nlm:aff></affiliation></author><author><name sortKey="Curtis, Keith R" sort="Curtis, Keith R" uniqKey="Curtis K" first="Keith R." last="Curtis">Keith R. Curtis</name><affiliation><nlm:aff id="A3">Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98124, USA</nlm:aff></affiliation></author><author><name sortKey="Fuchs, Charles S" sort="Fuchs, Charles S" uniqKey="Fuchs C" first="Charles S." last="Fuchs">Charles S. Fuchs</name><affiliation><nlm:aff id="A14">Department of Medicine, Brigham and Women’s Hospital, Brookline, Massachusetts 02115, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A15">Department of Medical Oncology, Dana-Farber Cancer Institute, Brookline, Massachusetts 02115, USA</nlm:aff></affiliation></author><author><name sortKey="Gala, Manish" sort="Gala, Manish" uniqKey="Gala M" first="Manish" last="Gala">Manish Gala</name><affiliation><nlm:aff id="A16">Division of Gastroenterology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA</nlm:aff></affiliation></author><author><name sortKey="Giovannucci, Edward L" sort="Giovannucci, Edward L" uniqKey="Giovannucci E" first="Edward L." last="Giovannucci">Edward L. Giovannucci</name><affiliation><nlm:aff id="A17">Harvard Medical School, Boston, Massachusetts 02114, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A18">Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital, Boston, Massachusetts 02115, USA</nlm:aff></affiliation></author><author><name sortKey="Gogarten, Stephanie M" sort="Gogarten, Stephanie M" uniqKey="Gogarten S" first="Stephanie M." last="Gogarten">Stephanie M. Gogarten</name><affiliation><nlm:aff id="A19">Department of Biostatistics, University of Washington, Seattle, Washington 98195, USA</nlm:aff></affiliation></author><author><name sortKey="Hayes, Richard B" sort="Hayes, Richard B" uniqKey="Hayes R" first="Richard B." last="Hayes">Richard B. Hayes</name><affiliation><nlm:aff id="A20">Division of Epidemiology, Department of Population Health, New York University School of Medicine, New York, New York 10016, USA</nlm:aff></affiliation></author><author><name sortKey="Henderson, Brian" sort="Henderson, Brian" uniqKey="Henderson B" first="Brian" last="Henderson">Brian Henderson</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Hunter, David J" sort="Hunter, David J" uniqKey="Hunter D" first="David J." last="Hunter">David J. Hunter</name><affiliation><nlm:aff id="A21">Program in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA</nlm:aff></affiliation></author><author><name sortKey="Jackson, Rebecca D" sort="Jackson, Rebecca D" uniqKey="Jackson R" first="Rebecca D." last="Jackson">Rebecca D. Jackson</name><affiliation><nlm:aff id="A22">Department of Medicine, Ohio State University, Columbus, Ohio 43210, USA</nlm:aff></affiliation></author><author><name sortKey="Kolonel, Laurence N" sort="Kolonel, Laurence N" uniqKey="Kolonel L" first="Laurence N." last="Kolonel">Laurence N. Kolonel</name><affiliation><nlm:aff id="A23">Office of Public Health Studies, University of Hawaii Manoa, Honolulu, Hawaii 96822, USA</nlm:aff></affiliation></author><author><name sortKey="Kooperberg, Charles" sort="Kooperberg, Charles" uniqKey="Kooperberg C" first="Charles" last="Kooperberg">Charles Kooperberg</name><affiliation><nlm:aff id="A3">Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98124, USA</nlm:aff></affiliation></author><author><name sortKey="Kury, Sebastien" sort="Kury, Sebastien" uniqKey="Kury S" first="Sébastien" last="Küry">Sébastien Küry</name><affiliation><nlm:aff id="A24">Service de Génétique Médicale, CHU Nantes, Nantes 44093, France</nlm:aff></affiliation></author><author><name sortKey="Lacroix, Andrea" sort="Lacroix, Andrea" uniqKey="Lacroix A" first="Andrea" last="Lacroix">Andrea Lacroix</name><affiliation><nlm:aff id="A3">Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98124, USA</nlm:aff></affiliation></author><author><name sortKey="Laurie, Cathy C" sort="Laurie, Cathy C" uniqKey="Laurie C" first="Cathy C." last="Laurie">Cathy C. Laurie</name><affiliation><nlm:aff id="A19">Department of Biostatistics, University of Washington, Seattle, Washington 98195, USA</nlm:aff></affiliation></author><author><name sortKey="Laurie, Cecelia A" sort="Laurie, Cecelia A" uniqKey="Laurie C" first="Cecelia A." last="Laurie">Cecelia A. Laurie</name><affiliation><nlm:aff id="A19">Department of Biostatistics, University of Washington, Seattle, Washington 98195, USA</nlm:aff></affiliation></author><author><name sortKey="Lemire, Mathieu" sort="Lemire, Mathieu" uniqKey="Lemire M" first="Mathieu" last="Lemire">Mathieu Lemire</name><affiliation><nlm:aff id="A25">Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada</nlm:aff></affiliation></author><author><name sortKey="Levine, David" sort="Levine, David" uniqKey="Levine D" first="David" last="Levine">David Levine</name><affiliation><nlm:aff id="A19">Department of Biostatistics, University of Washington, Seattle, Washington 98195, USA</nlm:aff></affiliation></author><author><name sortKey="Ma, Jing" sort="Ma, Jing" uniqKey="Ma J" first="Jing" last="Ma">Jing Ma</name><affiliation><nlm:aff id="A26">Harvard School of Public Health, Boston, Massachusetts 02114, USA</nlm:aff></affiliation></author><author><name sortKey="Makar, Karen W" sort="Makar, Karen W" uniqKey="Makar K" first="Karen W." last="Makar">Karen W. Makar</name><affiliation><nlm:aff id="A3">Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98124, USA</nlm:aff></affiliation></author><author><name sortKey="Qu, Conghui" sort="Qu, Conghui" uniqKey="Qu C" first="Conghui" last="Qu">Conghui Qu</name><affiliation><nlm:aff id="A3">Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98124, USA</nlm:aff></affiliation></author><author><name sortKey="Taverna, Darin" sort="Taverna, Darin" uniqKey="Taverna D" first="Darin" last="Taverna">Darin Taverna</name><affiliation><nlm:aff id="A27">Phoenix College, Phoenix, Arizona 85013, USA</nlm:aff></affiliation></author><author><name sortKey="Ulrich, Cornelia M" sort="Ulrich, Cornelia M" uniqKey="Ulrich C" first="Cornelia M." last="Ulrich">Cornelia M. Ulrich</name><affiliation><nlm:aff id="A3">Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98124, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A28">Division of Preventive Oncology, German Cancer Research Center, Heidelberg 69120, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A29">Department of Epidemiology, University of Washington School of Public Health, Seattle, Washington 98195, USA</nlm:aff></affiliation></author><author><name sortKey="Wu, Kana" sort="Wu, Kana" uniqKey="Wu K" first="Kana" last="Wu">Kana Wu</name><affiliation><nlm:aff id="A30">Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA</nlm:aff></affiliation></author><author><name sortKey="Kono, Suminori" sort="Kono, Suminori" uniqKey="Kono S" first="Suminori" last="Kono">Suminori Kono</name><affiliation><nlm:aff id="A31">Department of Preventive Medicine, Kyushu University, Fukuoka 812-8582, Japan</nlm:aff></affiliation></author><author><name sortKey="West, Dee W" sort="West, Dee W" uniqKey="West D" first="Dee W." last="West">Dee W. West</name><affiliation><nlm:aff id="A32">Cancer Registry of Greater California, Public Health Institute, Sacramento, California 95825, USA</nlm:aff></affiliation></author><author><name sortKey="Berndt, Sonja I" sort="Berndt, Sonja I" uniqKey="Berndt S" first="Sonja I." last="Berndt">Sonja I. Berndt</name><affiliation><nlm:aff id="A13">Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892-9776, USA</nlm:aff></affiliation></author><author><name sortKey="Bezieau, Stephane" sort="Bezieau, Stephane" uniqKey="Bezieau S" first="Stéphane" last="Bezieau">Stéphane Bezieau</name><affiliation><nlm:aff id="A33">Centre Hospitalier Universitaire Hotel-Dieu, Nantes 44093, France</nlm:aff></affiliation></author><author><name sortKey="Brenner, Hermann" sort="Brenner, Hermann" uniqKey="Brenner H" first="Hermann" last="Brenner">Hermann Brenner</name><affiliation><nlm:aff id="A11">Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg 69121, Germany</nlm:aff></affiliation></author><author><name sortKey="Campbell, Peter T" sort="Campbell, Peter T" uniqKey="Campbell P" first="Peter T." last="Campbell">Peter T. Campbell</name><affiliation><nlm:aff id="A34">Epidemiology Research Program, American Cancer Society, Atlanta, Georgia 30329-4251, USA</nlm:aff></affiliation></author><author><name sortKey="Chan, Andrew T" sort="Chan, Andrew T" uniqKey="Chan A" first="Andrew T." last="Chan">Andrew T. Chan</name><affiliation><nlm:aff id="A16">Division of Gastroenterology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A17">Harvard Medical School, Boston, Massachusetts 02114, USA</nlm:aff></affiliation></author><author><name sortKey="Chang Claude, Jenny" sort="Chang Claude, Jenny" uniqKey="Chang Claude J" first="Jenny" last="Chang-Claude">Jenny Chang-Claude</name><affiliation><nlm:aff id="A35">Unit of Genetic Epidemiology, Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg 69121, Germany</nlm:aff></affiliation></author><author><name sortKey="Coetzee, Gerhard A" sort="Coetzee, Gerhard A" uniqKey="Coetzee G" first="Gerhard A." last="Coetzee">Gerhard A. Coetzee</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Conti, David V" sort="Conti, David V" uniqKey="Conti D" first="David V." last="Conti">David V. Conti</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A36">Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Duggan, David" sort="Duggan, David" uniqKey="Duggan D" first="David" last="Duggan">David Duggan</name><affiliation><nlm:aff id="A37">Genetic Basis of Human Disease Division, Translational Genomics Research Institute, Phoenix, Arizona 85004, USA</nlm:aff></affiliation></author><author><name sortKey="Figueiredo, Jane C" sort="Figueiredo, Jane C" uniqKey="Figueiredo J" first="Jane C." last="Figueiredo">Jane C. Figueiredo</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Fortini, Barbara K" sort="Fortini, Barbara K" uniqKey="Fortini B" first="Barbara K." last="Fortini">Barbara K. Fortini</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Gallinger, Steven J" sort="Gallinger, Steven J" uniqKey="Gallinger S" first="Steven J." last="Gallinger">Steven J. Gallinger</name><affiliation><nlm:aff id="A38">Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario M5T 3L9, Canada</nlm:aff></affiliation></author><author><name sortKey="Gauderman, W James" sort="Gauderman, W James" uniqKey="Gauderman W" first="W. James" last="Gauderman">W. James Gauderman</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Giles, Graham" sort="Giles, Graham" uniqKey="Giles G" first="Graham" last="Giles">Graham Giles</name><affiliation><nlm:aff id="A39">Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria 3004, Australia</nlm:aff></affiliation></author><author><name sortKey="Green, Roger" sort="Green, Roger" uniqKey="Green R" first="Roger" last="Green">Roger Green</name><affiliation><nlm:aff id="A40">Discipline of Genetics, Memorial University of Newfoundland, St. John’s, Newfoundland A1B 3V6, Canada</nlm:aff></affiliation></author><author><name sortKey="Haile, Robert" sort="Haile, Robert" uniqKey="Haile R" first="Robert" last="Haile">Robert Haile</name><affiliation><nlm:aff id="A41">Department of Medicine, Division of Oncology, Stanford University, Stanford, California 94305, USA</nlm:aff></affiliation></author><author><name sortKey="Harrison, Tabitha A" sort="Harrison, Tabitha A" uniqKey="Harrison T" first="Tabitha A." last="Harrison">Tabitha A. Harrison</name><affiliation><nlm:aff id="A3">Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98124, USA</nlm:aff></affiliation></author><author><name sortKey="Hoffmeister, Michael" sort="Hoffmeister, Michael" uniqKey="Hoffmeister M" first="Michael" last="Hoffmeister">Michael Hoffmeister</name><affiliation><nlm:aff id="A11">Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg 69121, Germany</nlm:aff></affiliation></author><author><name sortKey="Hopper, John L" sort="Hopper, John L" uniqKey="Hopper J" first="John L." last="Hopper">John L. Hopper</name><affiliation><nlm:aff id="A42">Centre for MEGA Epidemiology, The University of Melbourne, Carlton, Victoria 3010, Australia</nlm:aff></affiliation></author><author><name sortKey="Hudson, Thomas J" sort="Hudson, Thomas J" uniqKey="Hudson T" first="Thomas J." last="Hudson">Thomas J. Hudson</name><affiliation><nlm:aff id="A43">Department of Genomics, Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada</nlm:aff></affiliation></author><author><name sortKey="Jacobs, Eric" sort="Jacobs, Eric" uniqKey="Jacobs E" first="Eric" last="Jacobs">Eric Jacobs</name><affiliation><nlm:aff id="A34">Epidemiology Research Program, American Cancer Society, Atlanta, Georgia 30329-4251, USA</nlm:aff></affiliation></author><author><name sortKey="Iwasaki, Motoki" sort="Iwasaki, Motoki" uniqKey="Iwasaki M" first="Motoki" last="Iwasaki">Motoki Iwasaki</name><affiliation><nlm:aff id="A44">Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo 104-0045, Japan</nlm:aff></affiliation></author><author><name sortKey="Jee, Sun Ha" sort="Jee, Sun Ha" uniqKey="Jee S" first="Sun Ha" last="Jee">Sun Ha Jee</name><affiliation><nlm:aff id="A45">Department of Epidemiology and Health Promotion, Graduate School of Public Health, Yonsei University, Seoul 120-749, South Korea</nlm:aff></affiliation></author><author><name sortKey="Jenkins, Mark" sort="Jenkins, Mark" uniqKey="Jenkins M" first="Mark" last="Jenkins">Mark Jenkins</name><affiliation><nlm:aff id="A46">Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, Victoria 3010, Australia</nlm:aff></affiliation></author><author><name sortKey="Jia, Wei Hua" sort="Jia, Wei Hua" uniqKey="Jia W" first="Wei-Hua" last="Jia">Wei-Hua Jia</name><affiliation><nlm:aff id="A47">State Key Laboratory of Oncology in South China, Cancer Center, Sun Yat-sen University, Guangzhou 510060, China</nlm:aff></affiliation></author><author><name sortKey="Joshi, Amit" sort="Joshi, Amit" uniqKey="Joshi A" first="Amit" last="Joshi">Amit Joshi</name><affiliation><nlm:aff id="A48">Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA</nlm:aff></affiliation></author><author><name sortKey="Li, Li" sort="Li, Li" uniqKey="Li L" first="Li" last="Li">Li Li</name><affiliation><nlm:aff id="A49">Department of Family Medicine and Community Health, Case Western Reserve University, Cleveland, Ohio 44106, USA</nlm:aff></affiliation></author><author><name sortKey="Lindor, Noralene M" sort="Lindor, Noralene M" uniqKey="Lindor N" first="Noralene M." last="Lindor">Noralene M. Lindor</name><affiliation><nlm:aff id="A50">Department of Health Science Research, Mayo Clinic, Scottsdale, Arizona 85259, USA</nlm:aff></affiliation></author><author><name sortKey="Matsuo, Keitaro" sort="Matsuo, Keitaro" uniqKey="Matsuo K" first="Keitaro" last="Matsuo">Keitaro Matsuo</name><affiliation><nlm:aff id="A31">Department of Preventive Medicine, Kyushu University, Fukuoka 812-8582, Japan</nlm:aff></affiliation></author><author><name sortKey="Moreno, Victor" sort="Moreno, Victor" uniqKey="Moreno V" first="Victor" last="Moreno">Victor Moreno</name><affiliation><nlm:aff id="A51">Cancer Epidemiology Service, DDCF, Catalan Institute of Oncology, IDIBELL, Barcelona 08908, Spain</nlm:aff></affiliation></author><author><name sortKey="Mukherjee, Bhramar" sort="Mukherjee, Bhramar" uniqKey="Mukherjee B" first="Bhramar" last="Mukherjee">Bhramar Mukherjee</name><affiliation><nlm:aff id="A52">Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA</nlm:aff></affiliation></author><author><name sortKey="Newcomb, Polly A" sort="Newcomb, Polly A" uniqKey="Newcomb P" first="Polly A." last="Newcomb">Polly A. Newcomb</name><affiliation><nlm:aff id="A53">Cancer Prevention Program, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA</nlm:aff></affiliation></author><author><name sortKey="Potter, John D" sort="Potter, John D" uniqKey="Potter J" first="John D." last="Potter">John D. Potter</name><affiliation><nlm:aff id="A53">Cancer Prevention Program, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA</nlm:aff></affiliation></author><author><name sortKey="Raskin, Leon" sort="Raskin, Leon" uniqKey="Raskin L" first="Leon" last="Raskin">Leon Raskin</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A54">Division of Epidemiology, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203-1738, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A55">Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee 37203-1738, USA</nlm:aff></affiliation></author><author><name sortKey="Rennert, Gad" sort="Rennert, Gad" uniqKey="Rennert G" first="Gad" last="Rennert">Gad Rennert</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A7">Department of Community Medicine and Epidemiology, Carmel Medical Center, Haifa 34361, Israel</nlm:aff></affiliation><affiliation><nlm:aff id="A8">Clalit Health Services National Cancer Control Center, Haifa 34361, Israel</nlm:aff></affiliation><affiliation><nlm:aff id="A56">Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3200003, Israel</nlm:aff></affiliation></author><author><name sortKey="Rosse, Stephanie" sort="Rosse, Stephanie" uniqKey="Rosse S" first="Stephanie" last="Rosse">Stephanie Rosse</name><affiliation><nlm:aff id="A3">Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98124, USA</nlm:aff></affiliation></author><author><name sortKey="Severi, Gianluca" sort="Severi, Gianluca" uniqKey="Severi G" first="Gianluca" last="Severi">Gianluca Severi</name><affiliation><nlm:aff id="A39">Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria 3004, Australia</nlm:aff></affiliation><affiliation><nlm:aff id="A57">Human Genetics Foundation (HuGeF), Torino 10126, Italy</nlm:aff></affiliation></author><author><name sortKey="Schoen, Robert E" sort="Schoen, Robert E" uniqKey="Schoen R" first="Robert E." last="Schoen">Robert E. Schoen</name><affiliation><nlm:aff id="A58">Department of Internal Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 151213, USA</nlm:aff></affiliation></author><author><name sortKey="Seminara, Daniela" sort="Seminara, Daniela" uniqKey="Seminara D" first="Daniela" last="Seminara">Daniela Seminara</name><affiliation><nlm:aff id="A59">Epidemiology and Genomics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA</nlm:aff></affiliation></author><author><name sortKey="Shu, Xiao Ou" sort="Shu, Xiao Ou" uniqKey="Shu X" first="Xiao-Ou" last="Shu">Xiao-Ou Shu</name><affiliation><nlm:aff id="A55">Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee 37203-1738, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A60">Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee 37203-1738, USA</nlm:aff></affiliation></author><author><name sortKey="Slattery, Martha L" sort="Slattery, Martha L" uniqKey="Slattery M" first="Martha L." last="Slattery">Martha L. Slattery</name><affiliation><nlm:aff id="A61">Department of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, Utah 84132, USA</nlm:aff></affiliation></author><author><name sortKey="Tsugane, Shoichiro" sort="Tsugane, Shoichiro" uniqKey="Tsugane S" first="Shoichiro" last="Tsugane">Shoichiro Tsugane</name><affiliation><nlm:aff id="A44">Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo 104-0045, Japan</nlm:aff></affiliation></author><author><name sortKey="White, Emily" sort="White, Emily" uniqKey="White E" first="Emily" last="White">Emily White</name><affiliation><nlm:aff id="A3">Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98124, USA</nlm:aff></affiliation></author><author><name sortKey="Xiang, Yong Bing" sort="Xiang, Yong Bing" uniqKey="Xiang Y" first="Yong-Bing" last="Xiang">Yong-Bing Xiang</name><affiliation><nlm:aff id="A62">Department of Epidemiology, Shanghai Cancer Institute, Shanghai 2200-25, China</nlm:aff></affiliation></author><author><name sortKey="Zanke, Brent W" sort="Zanke, Brent W" uniqKey="Zanke B" first="Brent W." last="Zanke">Brent W. Zanke</name><affiliation><nlm:aff id="A63">The University of Ottawa, Ottawa, Ontario K1N 6N5, Canada</nlm:aff></affiliation><affiliation><nlm:aff id="A64">Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, K1Y 4E9 Canada</nlm:aff></affiliation></author><author><name sortKey="Zheng, Wei" sort="Zheng, Wei" uniqKey="Zheng W" first="Wei" last="Zheng">Wei Zheng</name><affiliation><nlm:aff id="A54">Division of Epidemiology, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203-1738, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A55">Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee 37203-1738, USA</nlm:aff></affiliation></author><author><name sortKey="Le Marchand, Loic" sort="Le Marchand, Loic" uniqKey="Le Marchand L" first="Loic" last="Le Marchand">Loic Le Marchand</name><affiliation><nlm:aff id="A4">Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96822, USA</nlm:aff></affiliation></author><author><name sortKey="Casey, Graham" sort="Casey, Graham" uniqKey="Casey G" first="Graham" last="Casey">Graham Casey</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Gruber, Stephen B" sort="Gruber, Stephen B" uniqKey="Gruber S" first="Stephen B." last="Gruber">Stephen B. Gruber</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A2">Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Peters, Ulrike" sort="Peters, Ulrike" uniqKey="Peters U" first="Ulrike" last="Peters">Ulrike Peters</name><affiliation><nlm:aff id="A3">Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98124, USA</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">26151821</idno><idno type="pmc">4967357</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967357</idno><idno type="RBID">PMC:4967357</idno><idno type="doi">10.1038/ncomms8138</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">001E72</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001E72</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Genome-wide association study of colorectal cancer identifies six new susceptibility loci</title><author><name sortKey="Schumacher, Fredrick R" sort="Schumacher, Fredrick R" uniqKey="Schumacher F" first="Fredrick R." last="Schumacher">Fredrick R. Schumacher</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Schmit, Stephanie L" sort="Schmit, Stephanie L" uniqKey="Schmit S" first="Stephanie L." last="Schmit">Stephanie L. Schmit</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A2">Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Jiao, Shuo" sort="Jiao, Shuo" uniqKey="Jiao S" first="Shuo" last="Jiao">Shuo Jiao</name><affiliation><nlm:aff id="A3">Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98124, USA</nlm:aff></affiliation></author><author><name sortKey="Edlund, Christopher K" sort="Edlund, Christopher K" uniqKey="Edlund C" first="Christopher K." last="Edlund">Christopher K. Edlund</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Wang, Hansong" sort="Wang, Hansong" uniqKey="Wang H" first="Hansong" last="Wang">Hansong Wang</name><affiliation><nlm:aff id="A4">Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96822, USA</nlm:aff></affiliation></author><author><name sortKey="Zhang, Ben" sort="Zhang, Ben" uniqKey="Zhang B" first="Ben" last="Zhang">Ben Zhang</name><affiliation><nlm:aff id="A5">Department of General Surgery, Third Military Medical University Southwest Hospital, Chongqing 400038, China</nlm:aff></affiliation></author><author><name sortKey="Hsu, Li" sort="Hsu, Li" uniqKey="Hsu L" first="Li" last="Hsu">Li Hsu</name><affiliation><nlm:aff id="A3">Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98124, USA</nlm:aff></affiliation></author><author><name sortKey="Huang, Shu Chen" sort="Huang, Shu Chen" uniqKey="Huang S" first="Shu-Chen" last="Huang">Shu-Chen Huang</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Fischer, Christopher P" sort="Fischer, Christopher P" uniqKey="Fischer C" first="Christopher P." last="Fischer">Christopher P. Fischer</name><affiliation><nlm:aff id="A6">University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan 48105, USA</nlm:aff></affiliation></author><author><name sortKey="Harju, John F" sort="Harju, John F" uniqKey="Harju J" first="John F." last="Harju">John F. Harju</name><affiliation><nlm:aff id="A6">University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan 48105, USA</nlm:aff></affiliation></author><author><name sortKey="Idos, Gregory E" sort="Idos, Gregory E" uniqKey="Idos G" first="Gregory E." last="Idos">Gregory E. Idos</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Lejbkowicz, Flavio" sort="Lejbkowicz, Flavio" uniqKey="Lejbkowicz F" first="Flavio" last="Lejbkowicz">Flavio Lejbkowicz</name><affiliation><nlm:aff id="A7">Department of Community Medicine and Epidemiology, Carmel Medical Center, Haifa 34361, Israel</nlm:aff></affiliation><affiliation><nlm:aff id="A8">Clalit Health Services National Cancer Control Center, Haifa 34361, Israel</nlm:aff></affiliation></author><author><name sortKey="Manion, Frank J" sort="Manion, Frank J" uniqKey="Manion F" first="Frank J." last="Manion">Frank J. Manion</name><affiliation><nlm:aff id="A6">University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan 48105, USA</nlm:aff></affiliation></author><author><name sortKey="Mcdonnell, Kevin" sort="Mcdonnell, Kevin" uniqKey="Mcdonnell K" first="Kevin" last="Mcdonnell">Kevin Mcdonnell</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Mcneil, Caroline E" sort="Mcneil, Caroline E" uniqKey="Mcneil C" first="Caroline E." last="Mcneil">Caroline E. Mcneil</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Melas, Marilena" sort="Melas, Marilena" uniqKey="Melas M" first="Marilena" last="Melas">Marilena Melas</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Rennert, Hedy S" sort="Rennert, Hedy S" uniqKey="Rennert H" first="Hedy S." last="Rennert">Hedy S. Rennert</name><affiliation><nlm:aff id="A7">Department of Community Medicine and Epidemiology, Carmel Medical Center, Haifa 34361, Israel</nlm:aff></affiliation><affiliation><nlm:aff id="A8">Clalit Health Services National Cancer Control Center, Haifa 34361, Israel</nlm:aff></affiliation></author><author><name sortKey="Shi, Wei" sort="Shi, Wei" uniqKey="Shi W" first="Wei" last="Shi">Wei Shi</name><affiliation><nlm:aff id="A9">Department of Surgery, Children’s Hospital Los Angeles, Los Angeles, California 90027, USA</nlm:aff></affiliation></author><author><name sortKey="Thomas, Duncan C" sort="Thomas, Duncan C" uniqKey="Thomas D" first="Duncan C." last="Thomas">Duncan C. Thomas</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Van Den Berg, David J" sort="Van Den Berg, David J" uniqKey="Van Den Berg D" first="David J." last="Van Den Berg">David J. Van Den Berg</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Hutter, Carolyn M" sort="Hutter, Carolyn M" uniqKey="Hutter C" first="Carolyn M." last="Hutter">Carolyn M. Hutter</name><affiliation><nlm:aff id="A10">Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20892, USA</nlm:aff></affiliation></author><author><name sortKey="Aragaki, Aaron K" sort="Aragaki, Aaron K" uniqKey="Aragaki A" first="Aaron K." last="Aragaki">Aaron K. Aragaki</name><affiliation><nlm:aff id="A3">Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98124, USA</nlm:aff></affiliation></author><author><name sortKey="Butterbach, Katja" sort="Butterbach, Katja" uniqKey="Butterbach K" first="Katja" last="Butterbach">Katja Butterbach</name><affiliation><nlm:aff id="A11">Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg 69121, Germany</nlm:aff></affiliation></author><author><name sortKey="Caan, Bette J" sort="Caan, Bette J" uniqKey="Caan B" first="Bette J." last="Caan">Bette J. Caan</name><affiliation><nlm:aff id="A12">Division of Research, Kaiser Permanente Medical Care Program of Northern California, Oakland, California 94612, USA</nlm:aff></affiliation></author><author><name sortKey="Carlson, Christopher S" sort="Carlson, Christopher S" uniqKey="Carlson C" first="Christopher S." last="Carlson">Christopher S. Carlson</name><affiliation><nlm:aff id="A3">Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98124, USA</nlm:aff></affiliation></author><author><name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J." last="Chanock">Stephen J. Chanock</name><affiliation><nlm:aff id="A13">Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892-9776, USA</nlm:aff></affiliation></author><author><name sortKey="Curtis, Keith R" sort="Curtis, Keith R" uniqKey="Curtis K" first="Keith R." last="Curtis">Keith R. Curtis</name><affiliation><nlm:aff id="A3">Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98124, USA</nlm:aff></affiliation></author><author><name sortKey="Fuchs, Charles S" sort="Fuchs, Charles S" uniqKey="Fuchs C" first="Charles S." last="Fuchs">Charles S. Fuchs</name><affiliation><nlm:aff id="A14">Department of Medicine, Brigham and Women’s Hospital, Brookline, Massachusetts 02115, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A15">Department of Medical Oncology, Dana-Farber Cancer Institute, Brookline, Massachusetts 02115, USA</nlm:aff></affiliation></author><author><name sortKey="Gala, Manish" sort="Gala, Manish" uniqKey="Gala M" first="Manish" last="Gala">Manish Gala</name><affiliation><nlm:aff id="A16">Division of Gastroenterology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA</nlm:aff></affiliation></author><author><name sortKey="Giovannucci, Edward L" sort="Giovannucci, Edward L" uniqKey="Giovannucci E" first="Edward L." last="Giovannucci">Edward L. Giovannucci</name><affiliation><nlm:aff id="A17">Harvard Medical School, Boston, Massachusetts 02114, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A18">Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital, Boston, Massachusetts 02115, USA</nlm:aff></affiliation></author><author><name sortKey="Gogarten, Stephanie M" sort="Gogarten, Stephanie M" uniqKey="Gogarten S" first="Stephanie M." last="Gogarten">Stephanie M. Gogarten</name><affiliation><nlm:aff id="A19">Department of Biostatistics, University of Washington, Seattle, Washington 98195, USA</nlm:aff></affiliation></author><author><name sortKey="Hayes, Richard B" sort="Hayes, Richard B" uniqKey="Hayes R" first="Richard B." last="Hayes">Richard B. Hayes</name><affiliation><nlm:aff id="A20">Division of Epidemiology, Department of Population Health, New York University School of Medicine, New York, New York 10016, USA</nlm:aff></affiliation></author><author><name sortKey="Henderson, Brian" sort="Henderson, Brian" uniqKey="Henderson B" first="Brian" last="Henderson">Brian Henderson</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Hunter, David J" sort="Hunter, David J" uniqKey="Hunter D" first="David J." last="Hunter">David J. Hunter</name><affiliation><nlm:aff id="A21">Program in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA</nlm:aff></affiliation></author><author><name sortKey="Jackson, Rebecca D" sort="Jackson, Rebecca D" uniqKey="Jackson R" first="Rebecca D." last="Jackson">Rebecca D. Jackson</name><affiliation><nlm:aff id="A22">Department of Medicine, Ohio State University, Columbus, Ohio 43210, USA</nlm:aff></affiliation></author><author><name sortKey="Kolonel, Laurence N" sort="Kolonel, Laurence N" uniqKey="Kolonel L" first="Laurence N." last="Kolonel">Laurence N. Kolonel</name><affiliation><nlm:aff id="A23">Office of Public Health Studies, University of Hawaii Manoa, Honolulu, Hawaii 96822, USA</nlm:aff></affiliation></author><author><name sortKey="Kooperberg, Charles" sort="Kooperberg, Charles" uniqKey="Kooperberg C" first="Charles" last="Kooperberg">Charles Kooperberg</name><affiliation><nlm:aff id="A3">Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98124, USA</nlm:aff></affiliation></author><author><name sortKey="Kury, Sebastien" sort="Kury, Sebastien" uniqKey="Kury S" first="Sébastien" last="Küry">Sébastien Küry</name><affiliation><nlm:aff id="A24">Service de Génétique Médicale, CHU Nantes, Nantes 44093, France</nlm:aff></affiliation></author><author><name sortKey="Lacroix, Andrea" sort="Lacroix, Andrea" uniqKey="Lacroix A" first="Andrea" last="Lacroix">Andrea Lacroix</name><affiliation><nlm:aff id="A3">Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98124, USA</nlm:aff></affiliation></author><author><name sortKey="Laurie, Cathy C" sort="Laurie, Cathy C" uniqKey="Laurie C" first="Cathy C." last="Laurie">Cathy C. Laurie</name><affiliation><nlm:aff id="A19">Department of Biostatistics, University of Washington, Seattle, Washington 98195, USA</nlm:aff></affiliation></author><author><name sortKey="Laurie, Cecelia A" sort="Laurie, Cecelia A" uniqKey="Laurie C" first="Cecelia A." last="Laurie">Cecelia A. Laurie</name><affiliation><nlm:aff id="A19">Department of Biostatistics, University of Washington, Seattle, Washington 98195, USA</nlm:aff></affiliation></author><author><name sortKey="Lemire, Mathieu" sort="Lemire, Mathieu" uniqKey="Lemire M" first="Mathieu" last="Lemire">Mathieu Lemire</name><affiliation><nlm:aff id="A25">Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada</nlm:aff></affiliation></author><author><name sortKey="Levine, David" sort="Levine, David" uniqKey="Levine D" first="David" last="Levine">David Levine</name><affiliation><nlm:aff id="A19">Department of Biostatistics, University of Washington, Seattle, Washington 98195, USA</nlm:aff></affiliation></author><author><name sortKey="Ma, Jing" sort="Ma, Jing" uniqKey="Ma J" first="Jing" last="Ma">Jing Ma</name><affiliation><nlm:aff id="A26">Harvard School of Public Health, Boston, Massachusetts 02114, USA</nlm:aff></affiliation></author><author><name sortKey="Makar, Karen W" sort="Makar, Karen W" uniqKey="Makar K" first="Karen W." last="Makar">Karen W. Makar</name><affiliation><nlm:aff id="A3">Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98124, USA</nlm:aff></affiliation></author><author><name sortKey="Qu, Conghui" sort="Qu, Conghui" uniqKey="Qu C" first="Conghui" last="Qu">Conghui Qu</name><affiliation><nlm:aff id="A3">Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98124, USA</nlm:aff></affiliation></author><author><name sortKey="Taverna, Darin" sort="Taverna, Darin" uniqKey="Taverna D" first="Darin" last="Taverna">Darin Taverna</name><affiliation><nlm:aff id="A27">Phoenix College, Phoenix, Arizona 85013, USA</nlm:aff></affiliation></author><author><name sortKey="Ulrich, Cornelia M" sort="Ulrich, Cornelia M" uniqKey="Ulrich C" first="Cornelia M." last="Ulrich">Cornelia M. Ulrich</name><affiliation><nlm:aff id="A3">Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98124, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A28">Division of Preventive Oncology, German Cancer Research Center, Heidelberg 69120, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A29">Department of Epidemiology, University of Washington School of Public Health, Seattle, Washington 98195, USA</nlm:aff></affiliation></author><author><name sortKey="Wu, Kana" sort="Wu, Kana" uniqKey="Wu K" first="Kana" last="Wu">Kana Wu</name><affiliation><nlm:aff id="A30">Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA</nlm:aff></affiliation></author><author><name sortKey="Kono, Suminori" sort="Kono, Suminori" uniqKey="Kono S" first="Suminori" last="Kono">Suminori Kono</name><affiliation><nlm:aff id="A31">Department of Preventive Medicine, Kyushu University, Fukuoka 812-8582, Japan</nlm:aff></affiliation></author><author><name sortKey="West, Dee W" sort="West, Dee W" uniqKey="West D" first="Dee W." last="West">Dee W. West</name><affiliation><nlm:aff id="A32">Cancer Registry of Greater California, Public Health Institute, Sacramento, California 95825, USA</nlm:aff></affiliation></author><author><name sortKey="Berndt, Sonja I" sort="Berndt, Sonja I" uniqKey="Berndt S" first="Sonja I." last="Berndt">Sonja I. Berndt</name><affiliation><nlm:aff id="A13">Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892-9776, USA</nlm:aff></affiliation></author><author><name sortKey="Bezieau, Stephane" sort="Bezieau, Stephane" uniqKey="Bezieau S" first="Stéphane" last="Bezieau">Stéphane Bezieau</name><affiliation><nlm:aff id="A33">Centre Hospitalier Universitaire Hotel-Dieu, Nantes 44093, France</nlm:aff></affiliation></author><author><name sortKey="Brenner, Hermann" sort="Brenner, Hermann" uniqKey="Brenner H" first="Hermann" last="Brenner">Hermann Brenner</name><affiliation><nlm:aff id="A11">Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg 69121, Germany</nlm:aff></affiliation></author><author><name sortKey="Campbell, Peter T" sort="Campbell, Peter T" uniqKey="Campbell P" first="Peter T." last="Campbell">Peter T. Campbell</name><affiliation><nlm:aff id="A34">Epidemiology Research Program, American Cancer Society, Atlanta, Georgia 30329-4251, USA</nlm:aff></affiliation></author><author><name sortKey="Chan, Andrew T" sort="Chan, Andrew T" uniqKey="Chan A" first="Andrew T." last="Chan">Andrew T. Chan</name><affiliation><nlm:aff id="A16">Division of Gastroenterology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A17">Harvard Medical School, Boston, Massachusetts 02114, USA</nlm:aff></affiliation></author><author><name sortKey="Chang Claude, Jenny" sort="Chang Claude, Jenny" uniqKey="Chang Claude J" first="Jenny" last="Chang-Claude">Jenny Chang-Claude</name><affiliation><nlm:aff id="A35">Unit of Genetic Epidemiology, Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg 69121, Germany</nlm:aff></affiliation></author><author><name sortKey="Coetzee, Gerhard A" sort="Coetzee, Gerhard A" uniqKey="Coetzee G" first="Gerhard A." last="Coetzee">Gerhard A. Coetzee</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Conti, David V" sort="Conti, David V" uniqKey="Conti D" first="David V." last="Conti">David V. Conti</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A36">Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Duggan, David" sort="Duggan, David" uniqKey="Duggan D" first="David" last="Duggan">David Duggan</name><affiliation><nlm:aff id="A37">Genetic Basis of Human Disease Division, Translational Genomics Research Institute, Phoenix, Arizona 85004, USA</nlm:aff></affiliation></author><author><name sortKey="Figueiredo, Jane C" sort="Figueiredo, Jane C" uniqKey="Figueiredo J" first="Jane C." last="Figueiredo">Jane C. Figueiredo</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Fortini, Barbara K" sort="Fortini, Barbara K" uniqKey="Fortini B" first="Barbara K." last="Fortini">Barbara K. Fortini</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Gallinger, Steven J" sort="Gallinger, Steven J" uniqKey="Gallinger S" first="Steven J." last="Gallinger">Steven J. Gallinger</name><affiliation><nlm:aff id="A38">Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario M5T 3L9, Canada</nlm:aff></affiliation></author><author><name sortKey="Gauderman, W James" sort="Gauderman, W James" uniqKey="Gauderman W" first="W. James" last="Gauderman">W. James Gauderman</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Giles, Graham" sort="Giles, Graham" uniqKey="Giles G" first="Graham" last="Giles">Graham Giles</name><affiliation><nlm:aff id="A39">Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria 3004, Australia</nlm:aff></affiliation></author><author><name sortKey="Green, Roger" sort="Green, Roger" uniqKey="Green R" first="Roger" last="Green">Roger Green</name><affiliation><nlm:aff id="A40">Discipline of Genetics, Memorial University of Newfoundland, St. John’s, Newfoundland A1B 3V6, Canada</nlm:aff></affiliation></author><author><name sortKey="Haile, Robert" sort="Haile, Robert" uniqKey="Haile R" first="Robert" last="Haile">Robert Haile</name><affiliation><nlm:aff id="A41">Department of Medicine, Division of Oncology, Stanford University, Stanford, California 94305, USA</nlm:aff></affiliation></author><author><name sortKey="Harrison, Tabitha A" sort="Harrison, Tabitha A" uniqKey="Harrison T" first="Tabitha A." last="Harrison">Tabitha A. Harrison</name><affiliation><nlm:aff id="A3">Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98124, USA</nlm:aff></affiliation></author><author><name sortKey="Hoffmeister, Michael" sort="Hoffmeister, Michael" uniqKey="Hoffmeister M" first="Michael" last="Hoffmeister">Michael Hoffmeister</name><affiliation><nlm:aff id="A11">Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg 69121, Germany</nlm:aff></affiliation></author><author><name sortKey="Hopper, John L" sort="Hopper, John L" uniqKey="Hopper J" first="John L." last="Hopper">John L. Hopper</name><affiliation><nlm:aff id="A42">Centre for MEGA Epidemiology, The University of Melbourne, Carlton, Victoria 3010, Australia</nlm:aff></affiliation></author><author><name sortKey="Hudson, Thomas J" sort="Hudson, Thomas J" uniqKey="Hudson T" first="Thomas J." last="Hudson">Thomas J. Hudson</name><affiliation><nlm:aff id="A43">Department of Genomics, Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada</nlm:aff></affiliation></author><author><name sortKey="Jacobs, Eric" sort="Jacobs, Eric" uniqKey="Jacobs E" first="Eric" last="Jacobs">Eric Jacobs</name><affiliation><nlm:aff id="A34">Epidemiology Research Program, American Cancer Society, Atlanta, Georgia 30329-4251, USA</nlm:aff></affiliation></author><author><name sortKey="Iwasaki, Motoki" sort="Iwasaki, Motoki" uniqKey="Iwasaki M" first="Motoki" last="Iwasaki">Motoki Iwasaki</name><affiliation><nlm:aff id="A44">Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo 104-0045, Japan</nlm:aff></affiliation></author><author><name sortKey="Jee, Sun Ha" sort="Jee, Sun Ha" uniqKey="Jee S" first="Sun Ha" last="Jee">Sun Ha Jee</name><affiliation><nlm:aff id="A45">Department of Epidemiology and Health Promotion, Graduate School of Public Health, Yonsei University, Seoul 120-749, South Korea</nlm:aff></affiliation></author><author><name sortKey="Jenkins, Mark" sort="Jenkins, Mark" uniqKey="Jenkins M" first="Mark" last="Jenkins">Mark Jenkins</name><affiliation><nlm:aff id="A46">Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, Victoria 3010, Australia</nlm:aff></affiliation></author><author><name sortKey="Jia, Wei Hua" sort="Jia, Wei Hua" uniqKey="Jia W" first="Wei-Hua" last="Jia">Wei-Hua Jia</name><affiliation><nlm:aff id="A47">State Key Laboratory of Oncology in South China, Cancer Center, Sun Yat-sen University, Guangzhou 510060, China</nlm:aff></affiliation></author><author><name sortKey="Joshi, Amit" sort="Joshi, Amit" uniqKey="Joshi A" first="Amit" last="Joshi">Amit Joshi</name><affiliation><nlm:aff id="A48">Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA</nlm:aff></affiliation></author><author><name sortKey="Li, Li" sort="Li, Li" uniqKey="Li L" first="Li" last="Li">Li Li</name><affiliation><nlm:aff id="A49">Department of Family Medicine and Community Health, Case Western Reserve University, Cleveland, Ohio 44106, USA</nlm:aff></affiliation></author><author><name sortKey="Lindor, Noralene M" sort="Lindor, Noralene M" uniqKey="Lindor N" first="Noralene M." last="Lindor">Noralene M. Lindor</name><affiliation><nlm:aff id="A50">Department of Health Science Research, Mayo Clinic, Scottsdale, Arizona 85259, USA</nlm:aff></affiliation></author><author><name sortKey="Matsuo, Keitaro" sort="Matsuo, Keitaro" uniqKey="Matsuo K" first="Keitaro" last="Matsuo">Keitaro Matsuo</name><affiliation><nlm:aff id="A31">Department of Preventive Medicine, Kyushu University, Fukuoka 812-8582, Japan</nlm:aff></affiliation></author><author><name sortKey="Moreno, Victor" sort="Moreno, Victor" uniqKey="Moreno V" first="Victor" last="Moreno">Victor Moreno</name><affiliation><nlm:aff id="A51">Cancer Epidemiology Service, DDCF, Catalan Institute of Oncology, IDIBELL, Barcelona 08908, Spain</nlm:aff></affiliation></author><author><name sortKey="Mukherjee, Bhramar" sort="Mukherjee, Bhramar" uniqKey="Mukherjee B" first="Bhramar" last="Mukherjee">Bhramar Mukherjee</name><affiliation><nlm:aff id="A52">Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA</nlm:aff></affiliation></author><author><name sortKey="Newcomb, Polly A" sort="Newcomb, Polly A" uniqKey="Newcomb P" first="Polly A." last="Newcomb">Polly A. Newcomb</name><affiliation><nlm:aff id="A53">Cancer Prevention Program, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA</nlm:aff></affiliation></author><author><name sortKey="Potter, John D" sort="Potter, John D" uniqKey="Potter J" first="John D." last="Potter">John D. Potter</name><affiliation><nlm:aff id="A53">Cancer Prevention Program, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA</nlm:aff></affiliation></author><author><name sortKey="Raskin, Leon" sort="Raskin, Leon" uniqKey="Raskin L" first="Leon" last="Raskin">Leon Raskin</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A54">Division of Epidemiology, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203-1738, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A55">Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee 37203-1738, USA</nlm:aff></affiliation></author><author><name sortKey="Rennert, Gad" sort="Rennert, Gad" uniqKey="Rennert G" first="Gad" last="Rennert">Gad Rennert</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A7">Department of Community Medicine and Epidemiology, Carmel Medical Center, Haifa 34361, Israel</nlm:aff></affiliation><affiliation><nlm:aff id="A8">Clalit Health Services National Cancer Control Center, Haifa 34361, Israel</nlm:aff></affiliation><affiliation><nlm:aff id="A56">Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3200003, Israel</nlm:aff></affiliation></author><author><name sortKey="Rosse, Stephanie" sort="Rosse, Stephanie" uniqKey="Rosse S" first="Stephanie" last="Rosse">Stephanie Rosse</name><affiliation><nlm:aff id="A3">Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98124, USA</nlm:aff></affiliation></author><author><name sortKey="Severi, Gianluca" sort="Severi, Gianluca" uniqKey="Severi G" first="Gianluca" last="Severi">Gianluca Severi</name><affiliation><nlm:aff id="A39">Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria 3004, Australia</nlm:aff></affiliation><affiliation><nlm:aff id="A57">Human Genetics Foundation (HuGeF), Torino 10126, Italy</nlm:aff></affiliation></author><author><name sortKey="Schoen, Robert E" sort="Schoen, Robert E" uniqKey="Schoen R" first="Robert E." last="Schoen">Robert E. Schoen</name><affiliation><nlm:aff id="A58">Department of Internal Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 151213, USA</nlm:aff></affiliation></author><author><name sortKey="Seminara, Daniela" sort="Seminara, Daniela" uniqKey="Seminara D" first="Daniela" last="Seminara">Daniela Seminara</name><affiliation><nlm:aff id="A59">Epidemiology and Genomics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA</nlm:aff></affiliation></author><author><name sortKey="Shu, Xiao Ou" sort="Shu, Xiao Ou" uniqKey="Shu X" first="Xiao-Ou" last="Shu">Xiao-Ou Shu</name><affiliation><nlm:aff id="A55">Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee 37203-1738, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A60">Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee 37203-1738, USA</nlm:aff></affiliation></author><author><name sortKey="Slattery, Martha L" sort="Slattery, Martha L" uniqKey="Slattery M" first="Martha L." last="Slattery">Martha L. Slattery</name><affiliation><nlm:aff id="A61">Department of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, Utah 84132, USA</nlm:aff></affiliation></author><author><name sortKey="Tsugane, Shoichiro" sort="Tsugane, Shoichiro" uniqKey="Tsugane S" first="Shoichiro" last="Tsugane">Shoichiro Tsugane</name><affiliation><nlm:aff id="A44">Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo 104-0045, Japan</nlm:aff></affiliation></author><author><name sortKey="White, Emily" sort="White, Emily" uniqKey="White E" first="Emily" last="White">Emily White</name><affiliation><nlm:aff id="A3">Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98124, USA</nlm:aff></affiliation></author><author><name sortKey="Xiang, Yong Bing" sort="Xiang, Yong Bing" uniqKey="Xiang Y" first="Yong-Bing" last="Xiang">Yong-Bing Xiang</name><affiliation><nlm:aff id="A62">Department of Epidemiology, Shanghai Cancer Institute, Shanghai 2200-25, China</nlm:aff></affiliation></author><author><name sortKey="Zanke, Brent W" sort="Zanke, Brent W" uniqKey="Zanke B" first="Brent W." last="Zanke">Brent W. Zanke</name><affiliation><nlm:aff id="A63">The University of Ottawa, Ottawa, Ontario K1N 6N5, Canada</nlm:aff></affiliation><affiliation><nlm:aff id="A64">Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, K1Y 4E9 Canada</nlm:aff></affiliation></author><author><name sortKey="Zheng, Wei" sort="Zheng, Wei" uniqKey="Zheng W" first="Wei" last="Zheng">Wei Zheng</name><affiliation><nlm:aff id="A54">Division of Epidemiology, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203-1738, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A55">Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee 37203-1738, USA</nlm:aff></affiliation></author><author><name sortKey="Le Marchand, Loic" sort="Le Marchand, Loic" uniqKey="Le Marchand L" first="Loic" last="Le Marchand">Loic Le Marchand</name><affiliation><nlm:aff id="A4">Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96822, USA</nlm:aff></affiliation></author><author><name sortKey="Casey, Graham" sort="Casey, Graham" uniqKey="Casey G" first="Graham" last="Casey">Graham Casey</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Gruber, Stephen B" sort="Gruber, Stephen B" uniqKey="Gruber S" first="Stephen B." last="Gruber">Stephen B. Gruber</name><affiliation><nlm:aff id="A1">Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A2">Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</nlm:aff></affiliation></author><author><name sortKey="Peters, Ulrike" sort="Peters, Ulrike" uniqKey="Peters U" first="Ulrike" last="Peters">Ulrike Peters</name><affiliation><nlm:aff id="A3">Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98124, USA</nlm:aff></affiliation></author></analytic><series><title level="j">Nature communications</title><idno type="eISSN">2041-1723</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">Genetic susceptibility to colorectal cancer is caused by rare pathogenic mutations and common genetic variants that contribute to familial risk. Here we report the results of a two-stage association study with 18,299 cases of colorectal cancer and 19,656 controls, with follow-up of the most statistically significant genetic loci in 4,725 cases and 9,969 controls from two Asian consortia. We describe six new susceptibility loci reaching a genome-wide threshold of <italic>P</italic><5.0E-08. These findings provide additional insight into the underlying biological mechanisms of colorectal cancer and demonstrate the scientific value of large consortia-based genetic epidemiology studies.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">101528555</journal-id><journal-id journal-id-type="pubmed-jr-id">37539</journal-id><journal-id journal-id-type="nlm-ta">Nat Commun</journal-id><journal-id journal-id-type="iso-abbrev">Nat Commun</journal-id><journal-title-group><journal-title>Nature communications</journal-title></journal-title-group><issn pub-type="epub">2041-1723</issn></journal-meta><article-meta><article-id pub-id-type="pmid">26151821</article-id><article-id pub-id-type="pmc">4967357</article-id><article-id pub-id-type="doi">10.1038/ncomms8138</article-id><article-id pub-id-type="manuscript">NIHMS787387</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Genome-wide association study of colorectal cancer identifies six new susceptibility loci</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Schumacher</surname><given-names>Fredrick R.</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref rid="FN2" ref-type="author-notes">*</xref></contrib><contrib contrib-type="author"><name><surname>Schmit</surname><given-names>Stephanie L.</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref ref-type="aff" rid="A2">2</xref><xref rid="FN2" ref-type="author-notes">*</xref></contrib><contrib contrib-type="author"><name><surname>Jiao</surname><given-names>Shuo</given-names></name><xref ref-type="aff" rid="A3">3</xref><xref rid="FN2" ref-type="author-notes">*</xref></contrib><contrib contrib-type="author"><name><surname>Edlund</surname><given-names>Christopher K.</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Wang</surname><given-names>Hansong</given-names></name><xref ref-type="aff" rid="A4">4</xref></contrib><contrib contrib-type="author"><name><surname>Zhang</surname><given-names>Ben</given-names></name><xref ref-type="aff" rid="A5">5</xref></contrib><contrib contrib-type="author"><name><surname>Hsu</surname><given-names>Li</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Huang</surname><given-names>Shu-Chen</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Fischer</surname><given-names>Christopher P.</given-names></name><xref ref-type="aff" rid="A6">6</xref></contrib><contrib contrib-type="author"><name><surname>Harju</surname><given-names>John F.</given-names></name><xref ref-type="aff" rid="A6">6</xref></contrib><contrib contrib-type="author"><name><surname>Idos</surname><given-names>Gregory E.</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Lejbkowicz</surname><given-names>Flavio</given-names></name><xref ref-type="aff" rid="A7">7</xref><xref ref-type="aff" rid="A8">8</xref></contrib><contrib contrib-type="author"><name><surname>Manion</surname><given-names>Frank J.</given-names></name><xref ref-type="aff" rid="A6">6</xref></contrib><contrib contrib-type="author"><name><surname>McDonnell</surname><given-names>Kevin</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>McNeil</surname><given-names>Caroline E.</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Melas</surname><given-names>Marilena</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Rennert</surname><given-names>Hedy S.</given-names></name><xref ref-type="aff" rid="A7">7</xref><xref ref-type="aff" rid="A8">8</xref></contrib><contrib contrib-type="author"><name><surname>Shi</surname><given-names>Wei</given-names></name><xref ref-type="aff" rid="A9">9</xref></contrib><contrib contrib-type="author"><name><surname>Thomas</surname><given-names>Duncan C.</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Van Den Berg</surname><given-names>David J.</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Hutter</surname><given-names>Carolyn M.</given-names></name><xref ref-type="aff" rid="A10">10</xref></contrib><contrib contrib-type="author"><name><surname>Aragaki</surname><given-names>Aaron K.</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Butterbach</surname><given-names>Katja</given-names></name><xref ref-type="aff" rid="A11">11</xref></contrib><contrib contrib-type="author"><name><surname>Caan</surname><given-names>Bette J.</given-names></name><xref ref-type="aff" rid="A12">12</xref></contrib><contrib contrib-type="author"><name><surname>Carlson</surname><given-names>Christopher S.</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Chanock</surname><given-names>Stephen J.</given-names></name><xref ref-type="aff" rid="A13">13</xref></contrib><contrib contrib-type="author"><name><surname>Curtis</surname><given-names>Keith R.</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Fuchs</surname><given-names>Charles S.</given-names></name><xref ref-type="aff" rid="A14">14</xref><xref ref-type="aff" rid="A15">15</xref></contrib><contrib contrib-type="author"><name><surname>Gala</surname><given-names>Manish</given-names></name><xref ref-type="aff" rid="A16">16</xref></contrib><contrib contrib-type="author"><name><surname>Giovannucci</surname><given-names>Edward L.</given-names></name><xref ref-type="aff" rid="A17">17</xref><xref ref-type="aff" rid="A18">18</xref></contrib><contrib contrib-type="author"><name><surname>Gogarten</surname><given-names>Stephanie M.</given-names></name><xref ref-type="aff" rid="A19">19</xref></contrib><contrib contrib-type="author"><name><surname>Hayes</surname><given-names>Richard B.</given-names></name><xref ref-type="aff" rid="A20">20</xref></contrib><contrib contrib-type="author"><name><surname>Henderson</surname><given-names>Brian</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Hunter</surname><given-names>David J.</given-names></name><xref ref-type="aff" rid="A21">21</xref></contrib><contrib contrib-type="author"><name><surname>Jackson</surname><given-names>Rebecca D.</given-names></name><xref ref-type="aff" rid="A22">22</xref></contrib><contrib contrib-type="author"><name><surname>Kolonel</surname><given-names>Laurence N.</given-names></name><xref ref-type="aff" rid="A23">23</xref></contrib><contrib contrib-type="author"><name><surname>Kooperberg</surname><given-names>Charles</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Küry</surname><given-names>Sébastien</given-names></name><xref ref-type="aff" rid="A24">24</xref></contrib><contrib contrib-type="author"><name><surname>LaCroix</surname><given-names>Andrea</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Laurie</surname><given-names>Cathy C.</given-names></name><xref ref-type="aff" rid="A19">19</xref></contrib><contrib contrib-type="author"><name><surname>Laurie</surname><given-names>Cecelia A.</given-names></name><xref ref-type="aff" rid="A19">19</xref></contrib><contrib contrib-type="author"><name><surname>Lemire</surname><given-names>Mathieu</given-names></name><xref ref-type="aff" rid="A25">25</xref></contrib><contrib contrib-type="author"><name><surname>Levine</surname><given-names>David</given-names></name><xref ref-type="aff" rid="A19">19</xref></contrib><contrib contrib-type="author"><name><surname>Ma</surname><given-names>Jing</given-names></name><xref ref-type="aff" rid="A26">26</xref></contrib><contrib contrib-type="author"><name><surname>Makar</surname><given-names>Karen W.</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Qu</surname><given-names>Conghui</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Taverna</surname><given-names>Darin</given-names></name><xref ref-type="aff" rid="A27">27</xref></contrib><contrib contrib-type="author"><name><surname>Ulrich</surname><given-names>Cornelia M.</given-names></name><xref ref-type="aff" rid="A3">3</xref><xref ref-type="aff" rid="A28">28</xref><xref ref-type="aff" rid="A29">29</xref></contrib><contrib contrib-type="author"><name><surname>Wu</surname><given-names>Kana</given-names></name><xref ref-type="aff" rid="A30">30</xref></contrib><contrib contrib-type="author"><name><surname>Kono</surname><given-names>Suminori</given-names></name><xref ref-type="aff" rid="A31">31</xref></contrib><contrib contrib-type="author"><name><surname>West</surname><given-names>Dee W.</given-names></name><xref ref-type="aff" rid="A32">32</xref></contrib><contrib contrib-type="author"><name><surname>Berndt</surname><given-names>Sonja I.</given-names></name><xref ref-type="aff" rid="A13">13</xref></contrib><contrib contrib-type="author"><name><surname>Bezieau</surname><given-names>Stéphane</given-names></name><xref ref-type="aff" rid="A33">33</xref></contrib><contrib contrib-type="author"><name><surname>Brenner</surname><given-names>Hermann</given-names></name><xref ref-type="aff" rid="A11">11</xref></contrib><contrib contrib-type="author"><name><surname>Campbell</surname><given-names>Peter T.</given-names></name><xref ref-type="aff" rid="A34">34</xref></contrib><contrib contrib-type="author"><name><surname>Chan</surname><given-names>Andrew T.</given-names></name><xref ref-type="aff" rid="A16">16</xref><xref ref-type="aff" rid="A17">17</xref></contrib><contrib contrib-type="author"><name><surname>Chang-Claude</surname><given-names>Jenny</given-names></name><xref ref-type="aff" rid="A35">35</xref></contrib><contrib contrib-type="author"><name><surname>Coetzee</surname><given-names>Gerhard A.</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Conti</surname><given-names>David V.</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref ref-type="aff" rid="A36">36</xref></contrib><contrib contrib-type="author"><name><surname>Duggan</surname><given-names>David</given-names></name><xref ref-type="aff" rid="A37">37</xref></contrib><contrib contrib-type="author"><name><surname>Figueiredo</surname><given-names>Jane C.</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Fortini</surname><given-names>Barbara K.</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Gallinger</surname><given-names>Steven J.</given-names></name><xref ref-type="aff" rid="A38">38</xref></contrib><contrib contrib-type="author"><name><surname>Gauderman</surname><given-names>W. James</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Giles</surname><given-names>Graham</given-names></name><xref ref-type="aff" rid="A39">39</xref></contrib><contrib contrib-type="author"><name><surname>Green</surname><given-names>Roger</given-names></name><xref ref-type="aff" rid="A40">40</xref></contrib><contrib contrib-type="author"><name><surname>Haile</surname><given-names>Robert</given-names></name><xref ref-type="aff" rid="A41">41</xref></contrib><contrib contrib-type="author"><name><surname>Harrison</surname><given-names>Tabitha A.</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Hoffmeister</surname><given-names>Michael</given-names></name><xref ref-type="aff" rid="A11">11</xref></contrib><contrib contrib-type="author"><name><surname>Hopper</surname><given-names>John L.</given-names></name><xref ref-type="aff" rid="A42">42</xref></contrib><contrib contrib-type="author"><name><surname>Hudson</surname><given-names>Thomas J.</given-names></name><xref ref-type="aff" rid="A43">43</xref></contrib><contrib contrib-type="author"><name><surname>Jacobs</surname><given-names>Eric</given-names></name><xref ref-type="aff" rid="A34">34</xref></contrib><contrib contrib-type="author"><name><surname>Iwasaki</surname><given-names>Motoki</given-names></name><xref ref-type="aff" rid="A44">44</xref></contrib><contrib contrib-type="author"><name><surname>Jee</surname><given-names>Sun Ha</given-names></name><xref ref-type="aff" rid="A45">45</xref></contrib><contrib contrib-type="author"><name><surname>Jenkins</surname><given-names>Mark</given-names></name><xref ref-type="aff" rid="A46">46</xref></contrib><contrib contrib-type="author"><name><surname>Jia</surname><given-names>Wei-Hua</given-names></name><xref ref-type="aff" rid="A47">47</xref></contrib><contrib contrib-type="author"><name><surname>Joshi</surname><given-names>Amit</given-names></name><xref ref-type="aff" rid="A48">48</xref></contrib><contrib contrib-type="author"><name><surname>Li</surname><given-names>Li</given-names></name><xref ref-type="aff" rid="A49">49</xref></contrib><contrib contrib-type="author"><name><surname>Lindor</surname><given-names>Noralene M.</given-names></name><xref ref-type="aff" rid="A50">50</xref></contrib><contrib contrib-type="author"><name><surname>Matsuo</surname><given-names>Keitaro</given-names></name><xref ref-type="aff" rid="A31">31</xref></contrib><contrib contrib-type="author"><name><surname>Moreno</surname><given-names>Victor</given-names></name><xref ref-type="aff" rid="A51">51</xref></contrib><contrib contrib-type="author"><name><surname>Mukherjee</surname><given-names>Bhramar</given-names></name><xref ref-type="aff" rid="A52">52</xref></contrib><contrib contrib-type="author"><name><surname>Newcomb</surname><given-names>Polly A.</given-names></name><xref ref-type="aff" rid="A53">53</xref></contrib><contrib contrib-type="author"><name><surname>Potter</surname><given-names>John D.</given-names></name><xref ref-type="aff" rid="A53">53</xref></contrib><contrib contrib-type="author"><name><surname>Raskin</surname><given-names>Leon</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref ref-type="aff" rid="A54">54</xref><xref ref-type="aff" rid="A55">55</xref></contrib><contrib contrib-type="author"><name><surname>Rennert</surname><given-names>Gad</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref ref-type="aff" rid="A7">7</xref><xref ref-type="aff" rid="A8">8</xref><xref ref-type="aff" rid="A56">56</xref></contrib><contrib contrib-type="author"><name><surname>Rosse</surname><given-names>Stephanie</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Severi</surname><given-names>Gianluca</given-names></name><xref ref-type="aff" rid="A39">39</xref><xref ref-type="aff" rid="A57">57</xref></contrib><contrib contrib-type="author"><name><surname>Schoen</surname><given-names>Robert E.</given-names></name><xref ref-type="aff" rid="A58">58</xref></contrib><contrib contrib-type="author"><name><surname>Seminara</surname><given-names>Daniela</given-names></name><xref ref-type="aff" rid="A59">59</xref></contrib><contrib contrib-type="author"><name><surname>Shu</surname><given-names>Xiao-Ou</given-names></name><xref ref-type="aff" rid="A55">55</xref><xref ref-type="aff" rid="A60">60</xref></contrib><contrib contrib-type="author"><name><surname>Slattery</surname><given-names>Martha L.</given-names></name><xref ref-type="aff" rid="A61">61</xref></contrib><contrib contrib-type="author"><name><surname>Tsugane</surname><given-names>Shoichiro</given-names></name><xref ref-type="aff" rid="A44">44</xref></contrib><contrib contrib-type="author"><name><surname>White</surname><given-names>Emily</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Xiang</surname><given-names>Yong-Bing</given-names></name><xref ref-type="aff" rid="A62">62</xref></contrib><contrib contrib-type="author"><name><surname>Zanke</surname><given-names>Brent W.</given-names></name><xref ref-type="aff" rid="A63">63</xref><xref ref-type="aff" rid="A64">64</xref></contrib><contrib contrib-type="author"><name><surname>Zheng</surname><given-names>Wei</given-names></name><xref ref-type="aff" rid="A54">54</xref><xref ref-type="aff" rid="A55">55</xref><xref rid="FN3" ref-type="author-notes">**</xref></contrib><contrib contrib-type="author"><name><surname>Le Marchand</surname><given-names>Loic</given-names></name><xref ref-type="aff" rid="A4">4</xref><xref rid="FN3" ref-type="author-notes">**</xref></contrib><contrib contrib-type="author"><name><surname>Casey</surname><given-names>Graham</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref rid="FN3" ref-type="author-notes">**</xref></contrib><contrib contrib-type="author"><name><surname>Gruber</surname><given-names>Stephen B.</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref ref-type="aff" rid="A2">2</xref><xref rid="FN3" ref-type="author-notes">**</xref></contrib><contrib contrib-type="author"><name><surname>Peters</surname><given-names>Ulrike</given-names></name><xref ref-type="aff" rid="A3">3</xref><xref rid="FN3" ref-type="author-notes">**</xref></contrib></contrib-group><aff id="A1"><label>1</label>Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</aff><aff id="A2"><label>2</label>Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</aff><aff id="A3"><label>3</label>Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98124, USA</aff><aff id="A4"><label>4</label>Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96822, USA</aff><aff id="A5"><label>5</label>Department of General Surgery, Third Military Medical University Southwest Hospital, Chongqing 400038, China</aff><aff id="A6"><label>6</label>University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan 48105, USA</aff><aff id="A7"><label>7</label>Department of Community Medicine and Epidemiology, Carmel Medical Center, Haifa 34361, Israel</aff><aff id="A8"><label>8</label>Clalit Health Services National Cancer Control Center, Haifa 34361, Israel</aff><aff id="A9"><label>9</label>Department of Surgery, Children’s Hospital Los Angeles, Los Angeles, California 90027, USA</aff><aff id="A10"><label>10</label>Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20892, USA</aff><aff id="A11"><label>11</label>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg 69121, Germany</aff><aff id="A12"><label>12</label>Division of Research, Kaiser Permanente Medical Care Program of Northern California, Oakland, California 94612, USA</aff><aff id="A13"><label>13</label>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892-9776, USA</aff><aff id="A14"><label>14</label>Department of Medicine, Brigham and Women’s Hospital, Brookline, Massachusetts 02115, USA</aff><aff id="A15"><label>15</label>Department of Medical Oncology, Dana-Farber Cancer Institute, Brookline, Massachusetts 02115, USA</aff><aff id="A16"><label>16</label>Division of Gastroenterology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA</aff><aff id="A17"><label>17</label>Harvard Medical School, Boston, Massachusetts 02114, USA</aff><aff id="A18"><label>18</label>Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital, Boston, Massachusetts 02115, USA</aff><aff id="A19"><label>19</label>Department of Biostatistics, University of Washington, Seattle, Washington 98195, USA</aff><aff id="A20"><label>20</label>Division of Epidemiology, Department of Population Health, New York University School of Medicine, New York, New York 10016, USA</aff><aff id="A21"><label>21</label>Program in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA</aff><aff id="A22"><label>22</label>Department of Medicine, Ohio State University, Columbus, Ohio 43210, USA</aff><aff id="A23"><label>23</label>Office of Public Health Studies, University of Hawaii Manoa, Honolulu, Hawaii 96822, USA</aff><aff id="A24"><label>24</label>Service de Génétique Médicale, CHU Nantes, Nantes 44093, France</aff><aff id="A25"><label>25</label>Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada</aff><aff id="A26"><label>26</label>Harvard School of Public Health, Boston, Massachusetts 02114, USA</aff><aff id="A27"><label>27</label>Phoenix College, Phoenix, Arizona 85013, USA</aff><aff id="A28"><label>28</label>Division of Preventive Oncology, German Cancer Research Center, Heidelberg 69120, Germany</aff><aff id="A29"><label>29</label>Department of Epidemiology, University of Washington School of Public Health, Seattle, Washington 98195, USA</aff><aff id="A30"><label>30</label>Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA</aff><aff id="A31"><label>31</label>Department of Preventive Medicine, Kyushu University, Fukuoka 812-8582, Japan</aff><aff id="A32"><label>32</label>Cancer Registry of Greater California, Public Health Institute, Sacramento, California 95825, USA</aff><aff id="A33"><label>33</label>Centre Hospitalier Universitaire Hotel-Dieu, Nantes 44093, France</aff><aff id="A34"><label>34</label>Epidemiology Research Program, American Cancer Society, Atlanta, Georgia 30329-4251, USA</aff><aff id="A35"><label>35</label>Unit of Genetic Epidemiology, Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg 69121, Germany</aff><aff id="A36"><label>36</label>Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA</aff><aff id="A37"><label>37</label>Genetic Basis of Human Disease Division, Translational Genomics Research Institute, Phoenix, Arizona 85004, USA</aff><aff id="A38"><label>38</label>Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario M5T 3L9, Canada</aff><aff id="A39"><label>39</label>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria 3004, Australia</aff><aff id="A40"><label>40</label>Discipline of Genetics, Memorial University of Newfoundland, St. John’s, Newfoundland A1B 3V6, Canada</aff><aff id="A41"><label>41</label>Department of Medicine, Division of Oncology, Stanford University, Stanford, California 94305, USA</aff><aff id="A42"><label>42</label>Centre for MEGA Epidemiology, The University of Melbourne, Carlton, Victoria 3010, Australia</aff><aff id="A43"><label>43</label>Department of Genomics, Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada</aff><aff id="A44"><label>44</label>Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo 104-0045, Japan</aff><aff id="A45"><label>45</label>Department of Epidemiology and Health Promotion, Graduate School of Public Health, Yonsei University, Seoul 120-749, South Korea</aff><aff id="A46"><label>46</label>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, Victoria 3010, Australia</aff><aff id="A47"><label>47</label>State Key Laboratory of Oncology in South China, Cancer Center, Sun Yat-sen University, Guangzhou 510060, China</aff><aff id="A48"><label>48</label>Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA</aff><aff id="A49"><label>49</label>Department of Family Medicine and Community Health, Case Western Reserve University, Cleveland, Ohio 44106, USA</aff><aff id="A50"><label>50</label>Department of Health Science Research, Mayo Clinic, Scottsdale, Arizona 85259, USA</aff><aff id="A51"><label>51</label>Cancer Epidemiology Service, DDCF, Catalan Institute of Oncology, IDIBELL, Barcelona 08908, Spain</aff><aff id="A52"><label>52</label>Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA</aff><aff id="A53"><label>53</label>Cancer Prevention Program, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA</aff><aff id="A54"><label>54</label>Division of Epidemiology, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203-1738, USA</aff><aff id="A55"><label>55</label>Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee 37203-1738, USA</aff><aff id="A56"><label>56</label>Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3200003, Israel</aff><aff id="A57"><label>57</label>Human Genetics Foundation (HuGeF), Torino 10126, Italy</aff><aff id="A58"><label>58</label>Department of Internal Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 151213, USA</aff><aff id="A59"><label>59</label>Epidemiology and Genomics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA</aff><aff id="A60"><label>60</label>Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee 37203-1738, USA</aff><aff id="A61"><label>61</label>Department of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, Utah 84132, USA</aff><aff id="A62"><label>62</label>Department of Epidemiology, Shanghai Cancer Institute, Shanghai 2200-25, China</aff><aff id="A63"><label>63</label>The University of Ottawa, Ottawa, Ontario K1N 6N5, Canada</aff><aff id="A64"><label>64</label>Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, K1Y 4E9 Canada</aff><author-notes><corresp id="FN1"><underline>Corresponding Author:</underline> Stephen B. Gruber, M.D., Ph.D., M.P.H., USC Norris Comprehensive Cancer Center, 1441 Eastlake Avenue, 8302 Ezralow Tower, Los Angeles, CA 90089-9181, Phone: 323-865-0816, Fax:323-865-0102, <email>sgruber@usc.edu</email></corresp><fn id="FN2" fn-type="equal"><label>*</label><p>These authors contributed equally to this work.</p></fn><fn id="FN3"><label>**</label><p>These authors jointly supervised this work.</p></fn></author-notes><pub-date pub-type="nihms-submitted"><day>15</day><month>7</month><year>2016</year></pub-date><pub-date pub-type="epub"><day>07</day><month>7</month><year>2015</year></pub-date><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="pmc-release"><day>30</day><month>7</month><year>2016</year></pub-date><volume>6</volume><fpage>7138</fpage><lpage>7138</lpage><pmc-comment>elocation-id from pubmed: 10.1038/ncomms8138</pmc-comment>
<permissions><license license-type="permissions-link"><license-p>Reprints and permission information is available online at <ext-link ext-link-type="uri" xlink:href="http://npg.nature.com/reprintsandpermissions/">http://npg.nature.com/reprintsandpermissions/</ext-link></license-p></license></permissions><abstract><p id="P1">Genetic susceptibility to colorectal cancer is caused by rare pathogenic mutations and common genetic variants that contribute to familial risk. Here we report the results of a two-stage association study with 18,299 cases of colorectal cancer and 19,656 controls, with follow-up of the most statistically significant genetic loci in 4,725 cases and 9,969 controls from two Asian consortia. We describe six new susceptibility loci reaching a genome-wide threshold of <italic>P</italic><5.0E-08. These findings provide additional insight into the underlying biological mechanisms of colorectal cancer and demonstrate the scientific value of large consortia-based genetic epidemiology studies.</p></abstract></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Pmc/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001E72 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Corpus/biblio.hfd -nk 001E72 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Asie
|area= AustralieFrV1
|flux= Pmc
|étape= Corpus
|type= RBID
|clé=
|texte=
}}
| This area was generated with Dilib version V0.6.33. |  |