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<title xml:lang="en">The International Histocompatibility Working Group in Hematopoietic Cell Transplantation</title>
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<name sortKey="Petersdorf, Effie W" sort="Petersdorf, Effie W" uniqKey="Petersdorf E" first="Effie W." last="Petersdorf">Effie W. Petersdorf</name>
<affiliation>
<nlm:aff id="A1">Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Malkki, Mari" sort="Malkki, Mari" uniqKey="Malkki M" first="Mari" last="Malkki">Mari Malkki</name>
<affiliation>
<nlm:aff id="A2">Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Hsu, Katharine" sort="Hsu, Katharine" uniqKey="Hsu K" first="Katharine" last="Hsu">Katharine Hsu</name>
<affiliation>
<nlm:aff id="A3">Memorial Hospital, Memorial Sloan-Kettering Cancer Center, New York, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Bardy, Peter" sort="Bardy, Peter" uniqKey="Bardy P" first="Peter" last="Bardy">Peter Bardy</name>
<affiliation>
<nlm:aff id="A4">Red Cross Blood Transfusion Service, Adelaide, Australia</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Cesbron, Anne" sort="Cesbron, Anne" uniqKey="Cesbron A" first="Anne" last="Cesbron">Anne Cesbron</name>
<affiliation>
<nlm:aff id="A5">Laboratoire d'Histocompatibilité, EFS Pays de la Loire, Nantes, France</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Dickinson, Anne" sort="Dickinson, Anne" uniqKey="Dickinson A" first="Anne" last="Dickinson">Anne Dickinson</name>
<affiliation>
<nlm:aff id="A6">Haematological Sciences Institute of Cellular Medicine Newcastle University, Newcastle, United Kingdom</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Dubois, Valerie" sort="Dubois, Valerie" uniqKey="Dubois V" first="Valerie" last="Dubois">Valerie Dubois</name>
<affiliation>
<nlm:aff id="A7">EFS Rhone Alpes- Laboratoire HLA, Lyon, France</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Fleischhauer, Katharina" sort="Fleischhauer, Katharina" uniqKey="Fleischhauer K" first="Katharina" last="Fleischhauer">Katharina Fleischhauer</name>
<affiliation>
<nlm:aff id="A8">Instituto Scientifico H. San Raffaele, Milan, Italy</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Kawase, Takakazu" sort="Kawase, Takakazu" uniqKey="Kawase T" first="Takakazu" last="Kawase">Takakazu Kawase</name>
<affiliation>
<nlm:aff id="A9">Japan Marrow Donor Program, Tokyo, Japan and Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Madrigal, Alejandro" sort="Madrigal, Alejandro" uniqKey="Madrigal A" first="Alejandro" last="Madrigal">Alejandro Madrigal</name>
<affiliation>
<nlm:aff id="A10">Anthony Nolan Research Institute, London, United Kingdom</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Morishima, Yasuo" sort="Morishima, Yasuo" uniqKey="Morishima Y" first="Yasuo" last="Morishima">Yasuo Morishima</name>
<affiliation>
<nlm:aff id="A11">Japan Marrow Donor Program, Tokyo, Japan and Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Shaw, Bronwen" sort="Shaw, Bronwen" uniqKey="Shaw B" first="Bronwen" last="Shaw">Bronwen Shaw</name>
<affiliation>
<nlm:aff id="A12">Royal Marsden Hospital and Anthony Nolan Research Institute, London, United Kingdom</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Spellman, Stephen" sort="Spellman, Stephen" uniqKey="Spellman S" first="Stephen" last="Spellman">Stephen Spellman</name>
<affiliation>
<nlm:aff id="A13">Center for International Blood and Marrow Transplant Research, Minneapolis, MN, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Spierings, Eric" sort="Spierings, Eric" uniqKey="Spierings E" first="Eric" last="Spierings">Eric Spierings</name>
<affiliation>
<nlm:aff id="A14">University Medical Center Utrecht, Utrecht, The Netherlands</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Stern, Martin" sort="Stern, Martin" uniqKey="Stern M" first="Martin" last="Stern">Martin Stern</name>
<affiliation>
<nlm:aff id="A15">Division of Hematology, Kantonsspital, Basel, Switzerland</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Tiercy, Jean Marie" sort="Tiercy, Jean Marie" uniqKey="Tiercy J" first="Jean-Marie" last="Tiercy">Jean-Marie Tiercy</name>
<affiliation>
<nlm:aff id="A16">LNRH/Transplantation Immunology Unit, University Hospital, Geneva, Switzerland</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Velardi, Andrea" sort="Velardi, Andrea" uniqKey="Velardi A" first="Andrea" last="Velardi">Andrea Velardi</name>
<affiliation>
<nlm:aff id="A17">European Group for Blood and Marrow Transplantation, Italy</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Gooley, Ted" sort="Gooley, Ted" uniqKey="Gooley T" first="Ted" last="Gooley">Ted Gooley</name>
<affiliation>
<nlm:aff id="A18">Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA, USA</nlm:aff>
</affiliation>
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<title xml:lang="en" level="a" type="main">The International Histocompatibility Working Group in Hematopoietic Cell Transplantation</title>
<author>
<name sortKey="Petersdorf, Effie W" sort="Petersdorf, Effie W" uniqKey="Petersdorf E" first="Effie W." last="Petersdorf">Effie W. Petersdorf</name>
<affiliation>
<nlm:aff id="A1">Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Malkki, Mari" sort="Malkki, Mari" uniqKey="Malkki M" first="Mari" last="Malkki">Mari Malkki</name>
<affiliation>
<nlm:aff id="A2">Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Hsu, Katharine" sort="Hsu, Katharine" uniqKey="Hsu K" first="Katharine" last="Hsu">Katharine Hsu</name>
<affiliation>
<nlm:aff id="A3">Memorial Hospital, Memorial Sloan-Kettering Cancer Center, New York, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Bardy, Peter" sort="Bardy, Peter" uniqKey="Bardy P" first="Peter" last="Bardy">Peter Bardy</name>
<affiliation>
<nlm:aff id="A4">Red Cross Blood Transfusion Service, Adelaide, Australia</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Cesbron, Anne" sort="Cesbron, Anne" uniqKey="Cesbron A" first="Anne" last="Cesbron">Anne Cesbron</name>
<affiliation>
<nlm:aff id="A5">Laboratoire d'Histocompatibilité, EFS Pays de la Loire, Nantes, France</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Dickinson, Anne" sort="Dickinson, Anne" uniqKey="Dickinson A" first="Anne" last="Dickinson">Anne Dickinson</name>
<affiliation>
<nlm:aff id="A6">Haematological Sciences Institute of Cellular Medicine Newcastle University, Newcastle, United Kingdom</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Dubois, Valerie" sort="Dubois, Valerie" uniqKey="Dubois V" first="Valerie" last="Dubois">Valerie Dubois</name>
<affiliation>
<nlm:aff id="A7">EFS Rhone Alpes- Laboratoire HLA, Lyon, France</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Fleischhauer, Katharina" sort="Fleischhauer, Katharina" uniqKey="Fleischhauer K" first="Katharina" last="Fleischhauer">Katharina Fleischhauer</name>
<affiliation>
<nlm:aff id="A8">Instituto Scientifico H. San Raffaele, Milan, Italy</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Kawase, Takakazu" sort="Kawase, Takakazu" uniqKey="Kawase T" first="Takakazu" last="Kawase">Takakazu Kawase</name>
<affiliation>
<nlm:aff id="A9">Japan Marrow Donor Program, Tokyo, Japan and Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Madrigal, Alejandro" sort="Madrigal, Alejandro" uniqKey="Madrigal A" first="Alejandro" last="Madrigal">Alejandro Madrigal</name>
<affiliation>
<nlm:aff id="A10">Anthony Nolan Research Institute, London, United Kingdom</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Morishima, Yasuo" sort="Morishima, Yasuo" uniqKey="Morishima Y" first="Yasuo" last="Morishima">Yasuo Morishima</name>
<affiliation>
<nlm:aff id="A11">Japan Marrow Donor Program, Tokyo, Japan and Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Shaw, Bronwen" sort="Shaw, Bronwen" uniqKey="Shaw B" first="Bronwen" last="Shaw">Bronwen Shaw</name>
<affiliation>
<nlm:aff id="A12">Royal Marsden Hospital and Anthony Nolan Research Institute, London, United Kingdom</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Spellman, Stephen" sort="Spellman, Stephen" uniqKey="Spellman S" first="Stephen" last="Spellman">Stephen Spellman</name>
<affiliation>
<nlm:aff id="A13">Center for International Blood and Marrow Transplant Research, Minneapolis, MN, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Spierings, Eric" sort="Spierings, Eric" uniqKey="Spierings E" first="Eric" last="Spierings">Eric Spierings</name>
<affiliation>
<nlm:aff id="A14">University Medical Center Utrecht, Utrecht, The Netherlands</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Stern, Martin" sort="Stern, Martin" uniqKey="Stern M" first="Martin" last="Stern">Martin Stern</name>
<affiliation>
<nlm:aff id="A15">Division of Hematology, Kantonsspital, Basel, Switzerland</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Tiercy, Jean Marie" sort="Tiercy, Jean Marie" uniqKey="Tiercy J" first="Jean-Marie" last="Tiercy">Jean-Marie Tiercy</name>
<affiliation>
<nlm:aff id="A16">LNRH/Transplantation Immunology Unit, University Hospital, Geneva, Switzerland</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Velardi, Andrea" sort="Velardi, Andrea" uniqKey="Velardi A" first="Andrea" last="Velardi">Andrea Velardi</name>
<affiliation>
<nlm:aff id="A17">European Group for Blood and Marrow Transplantation, Italy</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Gooley, Ted" sort="Gooley, Ted" uniqKey="Gooley T" first="Ted" last="Gooley">Ted Gooley</name>
<affiliation>
<nlm:aff id="A18">Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA, USA</nlm:aff>
</affiliation>
</author>
</analytic>
<series>
<title level="j">International journal of immunogenetics</title>
<idno type="ISSN">1744-3121</idno>
<idno type="eISSN">1744-313X</idno>
<imprint>
<date when="2012">2012</date>
</imprint>
</series>
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<front>
<div type="abstract" xml:lang="en">
<title>Summary</title>
<p id="P1">The International Histocompatibility Working Group is a collaborative international effort to understand the HLA and non-HLA genetics of the transplantation barrier. The Working Group is comprised of experts in the fields of histocompatibility and immunogenetics, hematopoietic cell transplantation, and outcomes research. Data for 25855 unrelated donor transplants was submitted in support of research studies for the 16
<sup>th</sup>
International Histocompatibility Workshop. Active investigation is in progress in 7 key areas: the impact of HLA matching, role of race and ethnicity, identification of permissible HLA mismatches, haplotype-associated determinants, minor histocompatibility antigens, immune response genes, and KIR genetics. New hypotheses for the 16
<sup>th</sup>
workshop were developed for immunogenetic studies in cord blood and haploidentical related donor transplantation.</p>
</div>
</front>
</TEI>
<pmc article-type="research-article">
<pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-journal-id">101232337</journal-id>
<journal-id journal-id-type="pubmed-jr-id">32253</journal-id>
<journal-id journal-id-type="nlm-ta">Int J Immunogenet</journal-id>
<journal-id journal-id-type="iso-abbrev">Int. J. Immunogenet.</journal-id>
<journal-title-group>
<journal-title>International journal of immunogenetics</journal-title>
</journal-title-group>
<issn pub-type="ppub">1744-3121</issn>
<issn pub-type="epub">1744-313X</issn>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">23279968</article-id>
<article-id pub-id-type="pmc">3887040</article-id>
<article-id pub-id-type="doi">10.1111/iji.12022</article-id>
<article-id pub-id-type="manuscript">NIHMS418079</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Article</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>The International Histocompatibility Working Group in Hematopoietic Cell Transplantation</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Petersdorf</surname>
<given-names>Effie W.</given-names>
</name>
<email>epetersd@fhcrc.org</email>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Malkki</surname>
<given-names>Mari</given-names>
</name>
<email>mmalkki@fhcrc.org</email>
<xref ref-type="aff" rid="A2">2</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Hsu</surname>
<given-names>Katharine</given-names>
</name>
<email>hsuk@mskcc.org</email>
<xref ref-type="aff" rid="A3">3</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Bardy</surname>
<given-names>Peter</given-names>
</name>
<email>Peter.Bardy@health.sa.gov.au</email>
<xref ref-type="aff" rid="A4">4</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Cesbron</surname>
<given-names>Anne</given-names>
</name>
<email>Anne.Cesbron@efs.sante.fr</email>
<xref ref-type="aff" rid="A5">5</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Dickinson</surname>
<given-names>Anne</given-names>
</name>
<email>a.m.dickinson@newcastle.ac.uk</email>
<xref ref-type="aff" rid="A6">6</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Dubois</surname>
<given-names>Valerie</given-names>
</name>
<email>Valerie.dubois@efs.sante.fr</email>
<xref ref-type="aff" rid="A7">7</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Fleischhauer</surname>
<given-names>Katharina</given-names>
</name>
<email>fleischhauer.katharina@hsr.it</email>
<xref ref-type="aff" rid="A8">8</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Kawase</surname>
<given-names>Takakazu</given-names>
</name>
<email>tkawase@fhcrc.org</email>
<xref ref-type="aff" rid="A9">9</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Madrigal</surname>
<given-names>Alejandro</given-names>
</name>
<email>a.madrigal@ucl.ac.uk</email>
<xref ref-type="aff" rid="A10">10</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Morishima</surname>
<given-names>Yasuo</given-names>
</name>
<email>ymorisim@aichi-cc.jp</email>
<xref ref-type="aff" rid="A11">11</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Shaw</surname>
<given-names>Bronwen</given-names>
</name>
<email>bshaw@doctors.org.uk</email>
<xref ref-type="aff" rid="A12">12</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Spellman</surname>
<given-names>Stephen</given-names>
</name>
<email>sspellma@nmdp.org</email>
<xref ref-type="aff" rid="A13">13</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Spierings</surname>
<given-names>Eric</given-names>
</name>
<email>E.Spierings@umcutrecht.nl</email>
<xref ref-type="aff" rid="A14">14</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Stern</surname>
<given-names>Martin</given-names>
</name>
<email>martin.a.stern@gmail.com</email>
<xref ref-type="aff" rid="A15">15</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Tiercy</surname>
<given-names>Jean-Marie</given-names>
</name>
<email>Jean-Marie.Tiercy@unige.ch</email>
<xref ref-type="aff" rid="A16">16</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Velardi</surname>
<given-names>Andrea</given-names>
</name>
<email>velardi@unipg.it</email>
<xref ref-type="aff" rid="A17">17</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Gooley</surname>
<given-names>Ted</given-names>
</name>
<email>tedgoole@fhcrc.org</email>
<xref ref-type="aff" rid="A18">18</xref>
</contrib>
<on-behalf-of>on behalf of the International Histocompatibility Working Group in Hematopoietic Cell Transplantation</on-behalf-of>
</contrib-group>
<aff id="A1">
<label>1</label>
Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA, USA</aff>
<aff id="A2">
<label>2</label>
Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA, USA</aff>
<aff id="A3">
<label>3</label>
Memorial Hospital, Memorial Sloan-Kettering Cancer Center, New York, USA</aff>
<aff id="A4">
<label>4</label>
Red Cross Blood Transfusion Service, Adelaide, Australia</aff>
<aff id="A5">
<label>5</label>
Laboratoire d'Histocompatibilité, EFS Pays de la Loire, Nantes, France</aff>
<aff id="A6">
<label>6</label>
Haematological Sciences Institute of Cellular Medicine Newcastle University, Newcastle, United Kingdom</aff>
<aff id="A7">
<label>7</label>
EFS Rhone Alpes- Laboratoire HLA, Lyon, France</aff>
<aff id="A8">
<label>8</label>
Instituto Scientifico H. San Raffaele, Milan, Italy</aff>
<aff id="A9">
<label>9</label>
Japan Marrow Donor Program, Tokyo, Japan and Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan</aff>
<aff id="A10">
<label>10</label>
Anthony Nolan Research Institute, London, United Kingdom</aff>
<aff id="A11">
<label>11</label>
Japan Marrow Donor Program, Tokyo, Japan and Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan</aff>
<aff id="A12">
<label>12</label>
Royal Marsden Hospital and Anthony Nolan Research Institute, London, United Kingdom</aff>
<aff id="A13">
<label>13</label>
Center for International Blood and Marrow Transplant Research, Minneapolis, MN, USA</aff>
<aff id="A14">
<label>14</label>
University Medical Center Utrecht, Utrecht, The Netherlands</aff>
<aff id="A15">
<label>15</label>
Division of Hematology, Kantonsspital, Basel, Switzerland</aff>
<aff id="A16">
<label>16</label>
LNRH/Transplantation Immunology Unit, University Hospital, Geneva, Switzerland</aff>
<aff id="A17">
<label>17</label>
European Group for Blood and Marrow Transplantation, Italy</aff>
<aff id="A18">
<label>18</label>
Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA, USA</aff>
<author-notes>
<corresp id="FN1">Corresponding author: Effie W. Petersdorf, MD, Professor of Medicine and Member, Division of Clinical Research, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, Seattle, WA 98109 USA</corresp>
</author-notes>
<pub-date pub-type="nihms-submitted">
<day>6</day>
<month>12</month>
<year>2013</year>
</pub-date>
<pub-date pub-type="epub">
<day>28</day>
<month>12</month>
<year>2012</year>
</pub-date>
<pub-date pub-type="ppub">
<month>2</month>
<year>2013</year>
</pub-date>
<pub-date pub-type="pmc-release">
<day>01</day>
<month>2</month>
<year>2014</year>
</pub-date>
<volume>40</volume>
<issue>1</issue>
<elocation-id>10.1111/iji.12022</elocation-id>
<abstract>
<title>Summary</title>
<p id="P1">The International Histocompatibility Working Group is a collaborative international effort to understand the HLA and non-HLA genetics of the transplantation barrier. The Working Group is comprised of experts in the fields of histocompatibility and immunogenetics, hematopoietic cell transplantation, and outcomes research. Data for 25855 unrelated donor transplants was submitted in support of research studies for the 16
<sup>th</sup>
International Histocompatibility Workshop. Active investigation is in progress in 7 key areas: the impact of HLA matching, role of race and ethnicity, identification of permissible HLA mismatches, haplotype-associated determinants, minor histocompatibility antigens, immune response genes, and KIR genetics. New hypotheses for the 16
<sup>th</sup>
workshop were developed for immunogenetic studies in cord blood and haploidentical related donor transplantation.</p>
</abstract>
<funding-group>
<award-group>
<funding-source country="United States">National Institute of Allergy and Infectious Diseases Extramural Activities : NIAID</funding-source>
<award-id>U01 AI069197 || AI</award-id>
</award-group>
<award-group>
<funding-source country="United States">National Cancer Institute : NCI</funding-source>
<award-id>P01 CA018029 || CA</award-id>
</award-group>
</funding-group>
</article-meta>
</front>
</pmc>
</record>

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