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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Genetic studies of body mass index yield new insights for obesity biology</title><author><name sortKey="Locke, Adam E" sort="Locke, Adam E" uniqKey="Locke A" first="Adam E." last="Locke">Adam E. Locke</name><affiliation><nlm:aff id="A1">Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation></author><author><name sortKey="Kahali, Bratati" sort="Kahali, Bratati" uniqKey="Kahali B" first="Bratati" last="Kahali">Bratati Kahali</name><affiliation><nlm:aff id="A2">Department of Internal Medicine, Division of Gastroenterology, and Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation></author><author><name sortKey="Berndt, Sonja I" sort="Berndt, Sonja I" uniqKey="Berndt S" first="Sonja I." last="Berndt">Sonja I. Berndt</name><affiliation><nlm:aff id="A3">Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.</nlm:aff></affiliation></author><author><name sortKey="Justice, Anne E" sort="Justice, Anne E" uniqKey="Justice A" first="Anne E." last="Justice">Anne E. Justice</name><affiliation><nlm:aff id="A4">Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.</nlm:aff></affiliation></author><author><name sortKey="Pers, Tune H" sort="Pers, Tune H" uniqKey="Pers T" first="Tune H." last="Pers">Tune H. Pers</name><affiliation><nlm:aff id="A5">Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children’s Hospital, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A6">Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A7">Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A8">Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby 2800, Denmark.</nlm:aff></affiliation></author><author><name sortKey="Day, Felix R" sort="Day, Felix R" uniqKey="Day F" first="Felix R." last="Day">Felix R. Day</name><affiliation><nlm:aff id="A9">MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:aff></affiliation></author><author><name sortKey="Powell, Corey" sort="Powell, Corey" uniqKey="Powell C" first="Corey" last="Powell">Corey Powell</name><affiliation><nlm:aff id="A2">Department of Internal Medicine, Division of Gastroenterology, and Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation></author><author><name sortKey="Vedantam, Sailaja" sort="Vedantam, Sailaja" uniqKey="Vedantam S" first="Sailaja" last="Vedantam">Sailaja Vedantam</name><affiliation><nlm:aff id="A5">Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children’s Hospital, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A6">Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.</nlm:aff></affiliation></author><author><name sortKey="Buchkovich, Martin L" sort="Buchkovich, Martin L" uniqKey="Buchkovich M" first="Martin L." last="Buchkovich">Martin L. Buchkovich</name><affiliation><nlm:aff id="A10">Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.</nlm:aff></affiliation></author><author><name sortKey="Yang, Jian" sort="Yang, Jian" uniqKey="Yang J" first="Jian" last="Yang">Jian Yang</name><affiliation><nlm:aff id="A11">Queensland Brain Institute, The University of Queensland, Brisbane 4072, Australia.</nlm:aff></affiliation><affiliation><nlm:aff id="A12">The University of Queensland Diamantina Institute, The Translation Research Institute, Brisbane 4012, Australia.</nlm:aff></affiliation></author><author><name sortKey="Croteau Chonka, Damien C" sort="Croteau Chonka, Damien C" uniqKey="Croteau Chonka D" first="Damien C." last="Croteau-Chonka">Damien C. Croteau-Chonka</name><affiliation><nlm:aff id="A10">Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A13">Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation></author><author><name sortKey="Esko, Tonu" sort="Esko, Tonu" uniqKey="Esko T" first="Tonu" last="Esko">Tonu Esko</name><affiliation><nlm:aff id="A5">Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children’s Hospital, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A6">Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A7">Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A14">Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.</nlm:aff></affiliation></author><author><name sortKey="Fall, Tove" sort="Fall, Tove" uniqKey="Fall T" first="Tove" last="Fall">Tove Fall</name><affiliation><nlm:aff id="A15">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden.</nlm:aff></affiliation><affiliation><nlm:aff id="A16">Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.</nlm:aff></affiliation><affiliation><nlm:aff id="A17">Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala 75185, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Ferreira, Teresa" sort="Ferreira, Teresa" uniqKey="Ferreira T" first="Teresa" last="Ferreira">Teresa Ferreira</name><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation></author><author><name sortKey="Gustafsson, Stefan" sort="Gustafsson, Stefan" uniqKey="Gustafsson S" first="Stefan" last="Gustafsson">Stefan Gustafsson</name><affiliation><nlm:aff id="A16">Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.</nlm:aff></affiliation><affiliation><nlm:aff id="A17">Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala 75185, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Kutalik, Zoltan" sort="Kutalik, Zoltan" uniqKey="Kutalik Z" first="Zoltán" last="Kutalik">Zoltán Kutalik</name><affiliation><nlm:aff id="A19">Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne 1010, Switzerland.</nlm:aff></affiliation><affiliation><nlm:aff id="A20">Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland.</nlm:aff></affiliation><affiliation><nlm:aff id="A21">Department of Medical Genetics, University of Lausanne, Lausanne 1005, Switzerland.</nlm:aff></affiliation></author><author><name sortKey="Luan, Jian N" sort="Luan, Jian N" uniqKey="Luan J" first="Jian N" last="Luan">Jian N Luan</name><affiliation><nlm:aff id="A9">MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:aff></affiliation></author><author><name sortKey="M Gi, Reedik" sort="M Gi, Reedik" uniqKey="M Gi R" first="Reedik" last="M Gi">Reedik M Gi</name><affiliation><nlm:aff id="A14">Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.</nlm:aff></affiliation><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation></author><author><name sortKey="Randall, Joshua C" sort="Randall, Joshua C" uniqKey="Randall J" first="Joshua C." last="Randall">Joshua C. Randall</name><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A22">Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.</nlm:aff></affiliation></author><author><name sortKey="Winkler, Thomas W" sort="Winkler, Thomas W" uniqKey="Winkler T" first="Thomas W." last="Winkler">Thomas W. Winkler</name><affiliation><nlm:aff id="A23">Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, D-93053 Regensburg, Germany.</nlm:aff></affiliation></author><author><name sortKey="Wood, Andrew R" sort="Wood, Andrew R" uniqKey="Wood A" first="Andrew R." last="Wood">Andrew R. Wood</name><affiliation><nlm:aff id="A24">Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK.</nlm:aff></affiliation></author><author><name sortKey="Workalemahu, Tsegaselassie" sort="Workalemahu, Tsegaselassie" uniqKey="Workalemahu T" first="Tsegaselassie" last="Workalemahu">Tsegaselassie Workalemahu</name><affiliation><nlm:aff id="A25">Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation></author><author><name sortKey="Faul, Jessica D" sort="Faul, Jessica D" uniqKey="Faul J" first="Jessica D." last="Faul">Jessica D. Faul</name><affiliation><nlm:aff id="A26">Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan 48104, USA.</nlm:aff></affiliation></author><author><name sortKey="Smith, Jennifer A" sort="Smith, Jennifer A" uniqKey="Smith J" first="Jennifer A." last="Smith">Jennifer A. Smith</name><affiliation><nlm:aff id="A27">Department of Epidemiology, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation></author><author><name sortKey="Zhao, Jing Hua" sort="Zhao, Jing Hua" uniqKey="Zhao J" first="Jing Hua" last="Zhao">Jing Hua Zhao</name><affiliation><nlm:aff id="A9">MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:aff></affiliation></author><author><name sortKey="Zhao, Wei" sort="Zhao, Wei" uniqKey="Zhao W" first="Wei" last="Zhao">Wei Zhao</name><affiliation><nlm:aff id="A27">Department of Epidemiology, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation></author><author><name sortKey="Chen, Jin" sort="Chen, Jin" uniqKey="Chen J" first="Jin" last="Chen">Jin Chen</name><affiliation><nlm:aff id="A28">Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation></author><author><name sortKey="Fehrmann, Rudolf" sort="Fehrmann, Rudolf" uniqKey="Fehrmann R" first="Rudolf" last="Fehrmann">Rudolf Fehrmann</name><affiliation><nlm:aff id="A29">Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Hedman, Sa K" sort="Hedman, Sa K" uniqKey="Hedman " first=" Sa K." last="Hedman"> Sa K. Hedman</name><affiliation><nlm:aff id="A16">Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.</nlm:aff></affiliation><affiliation><nlm:aff id="A17">Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala 75185, Sweden.</nlm:aff></affiliation><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation></author><author><name sortKey="Karjalainen, Juha" sort="Karjalainen, Juha" uniqKey="Karjalainen J" first="Juha" last="Karjalainen">Juha Karjalainen</name><affiliation><nlm:aff id="A29">Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Schmidt, Ellen M" sort="Schmidt, Ellen M" uniqKey="Schmidt E" first="Ellen M." last="Schmidt">Ellen M. Schmidt</name><affiliation><nlm:aff id="A30">Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation></author><author><name sortKey="Absher, Devin" sort="Absher, Devin" uniqKey="Absher D" first="Devin" last="Absher">Devin Absher</name><affiliation><nlm:aff id="A31">HudsonAlpha Institute for Biotechnology, Huntsville, Alabama 35806, USA.</nlm:aff></affiliation></author><author><name sortKey="Amin, Najaf" sort="Amin, Najaf" uniqKey="Amin N" first="Najaf" last="Amin">Najaf Amin</name><affiliation><nlm:aff id="A32">Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC University Medical Center, 3015 GE Rotterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Anderson, Denise" sort="Anderson, Denise" uniqKey="Anderson D" first="Denise" last="Anderson">Denise Anderson</name><affiliation><nlm:aff id="A33">Telethon Institute for Child Health Research, Centre for Child Health Research, The University of Western Australia, Perth, Western Australia 6008, Australia.</nlm:aff></affiliation></author><author><name sortKey="Beekman, Marian" sort="Beekman, Marian" uniqKey="Beekman M" first="Marian" last="Beekman">Marian Beekman</name><affiliation><nlm:aff id="A34">Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A35">Department of Molecular Epidemiology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Bolton, Jennifer L" sort="Bolton, Jennifer L" uniqKey="Bolton J" first="Jennifer L." last="Bolton">Jennifer L. Bolton</name><affiliation><nlm:aff id="A36">Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK.</nlm:aff></affiliation></author><author><name sortKey="Bragg Gresham, Jennifer L" sort="Bragg Gresham, Jennifer L" uniqKey="Bragg Gresham J" first="Jennifer L." last="Bragg-Gresham">Jennifer L. Bragg-Gresham</name><affiliation><nlm:aff id="A1">Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A37">Kidney Epidemiology and Cost Center, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation></author><author><name sortKey="Buyske, Steven" sort="Buyske, Steven" uniqKey="Buyske S" first="Steven" last="Buyske">Steven Buyske</name><affiliation><nlm:aff id="A38">Department of Statistics & Biostatistics, Rutgers University, Piscataway, New Jersey 08854, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A39">Department of Genetics, Rutgers University, Piscataway, New Jersey 08854, USA.</nlm:aff></affiliation></author><author><name sortKey="Demirkan, Ayse" sort="Demirkan, Ayse" uniqKey="Demirkan A" first="Ayse" last="Demirkan">Ayse Demirkan</name><affiliation><nlm:aff id="A32">Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC University Medical Center, 3015 GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A40">Department of Human Genetics, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Deng, Guohong" sort="Deng, Guohong" uniqKey="Deng G" first="Guohong" last="Deng">Guohong Deng</name><affiliation><nlm:aff id="A41">Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A42">Department of Gastroenterology and Hepatology, Imperial College London, London W2 1PG, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A43">Institute of infectious Diseases, Southwest Hospital, Third Military Medical University, Chongqing, China.</nlm:aff></affiliation></author><author><name sortKey="Ehret, Georg B" sort="Ehret, Georg B" uniqKey="Ehret G" first="Georg B." last="Ehret">Georg B. Ehret</name><affiliation><nlm:aff id="A44">Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A45">Cardiology, Department of Specialties of Internal Medicine, Geneva University Hospital, Geneva 1211, Switzerland.</nlm:aff></affiliation></author><author><name sortKey="Feenstra, Bjarke" sort="Feenstra, Bjarke" uniqKey="Feenstra B" first="Bjarke" last="Feenstra">Bjarke Feenstra</name><affiliation><nlm:aff id="A46">Department of Epidemiology Research, Statens Serum Institut, Copenhagen DK-2300, Denmark.</nlm:aff></affiliation></author><author><name sortKey="Feitosa, Mary F" sort="Feitosa, Mary F" uniqKey="Feitosa M" first="Mary F." last="Feitosa">Mary F. Feitosa</name><affiliation><nlm:aff id="A47">Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:aff></affiliation></author><author><name sortKey="Fischer, Krista" sort="Fischer, Krista" uniqKey="Fischer K" first="Krista" last="Fischer">Krista Fischer</name><affiliation><nlm:aff id="A14">Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.</nlm:aff></affiliation></author><author><name sortKey="Goel, Anuj" sort="Goel, Anuj" uniqKey="Goel A" first="Anuj" last="Goel">Anuj Goel</name><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A48">Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, UK.</nlm:aff></affiliation></author><author><name sortKey="Gong, Jian" sort="Gong, Jian" uniqKey="Gong J" first="Jian" last="Gong">Jian Gong</name><affiliation><nlm:aff id="A49">Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.</nlm:aff></affiliation></author><author><name sortKey="Jackson, Anne U" sort="Jackson, Anne U" uniqKey="Jackson A" first="Anne U." last="Jackson">Anne U. Jackson</name><affiliation><nlm:aff id="A1">Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation></author><author><name sortKey="Kanoni, Stavroula" sort="Kanoni, Stavroula" uniqKey="Kanoni S" first="Stavroula" last="Kanoni">Stavroula Kanoni</name><affiliation><nlm:aff id="A50">William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.</nlm:aff></affiliation></author><author><name sortKey="Kleber, Marcus E" sort="Kleber, Marcus E" uniqKey="Kleber M" first="Marcus E." last="Kleber">Marcus E. Kleber</name><affiliation><nlm:aff id="A51">Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, D-68187 Mannheim, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A52">Department of Internal Medicine II, Ulm University Medical Centre, D-89081 Ulm, Germany.</nlm:aff></affiliation></author><author><name sortKey="Kristiansson, Kati" sort="Kristiansson, Kati" uniqKey="Kristiansson K" first="Kati" last="Kristiansson">Kati Kristiansson</name><affiliation><nlm:aff id="A53">National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:aff></affiliation></author><author><name sortKey="Lim, Unhee" sort="Lim, Unhee" uniqKey="Lim U" first="Unhee" last="Lim">Unhee Lim</name><affiliation><nlm:aff id="A54">Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96813, USA.</nlm:aff></affiliation></author><author><name sortKey="Lotay, Vaneet" sort="Lotay, Vaneet" uniqKey="Lotay V" first="Vaneet" last="Lotay">Vaneet Lotay</name><affiliation><nlm:aff id="A55">The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:aff></affiliation></author><author><name sortKey="Mangino, Massimo" sort="Mangino, Massimo" uniqKey="Mangino M" first="Massimo" last="Mangino">Massimo Mangino</name><affiliation><nlm:aff id="A56">Department of Twin Research and Genetic Epidemiology, King’s College London, London SE1 7EH, UK.</nlm:aff></affiliation></author><author><name sortKey="Leach, Irene Mateo" sort="Leach, Irene Mateo" uniqKey="Leach I" first="Irene Mateo" last="Leach">Irene Mateo Leach</name><affiliation><nlm:aff id="A57">Department of Cardiology, University Medical Center Groningen, University of Groningen, 9700RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Medina Gomez, Carolina" sort="Medina Gomez, Carolina" uniqKey="Medina Gomez C" first="Carolina" last="Medina-Gomez">Carolina Medina-Gomez</name><affiliation><nlm:aff id="A58">Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A59">Department of Epidemiology, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A60">Department of Internal Medicine, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Medland, Sarah E" sort="Medland, Sarah E" uniqKey="Medland S" first="Sarah E." last="Medland">Sarah E. Medland</name><affiliation><nlm:aff id="A61">QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4006, Australia.</nlm:aff></affiliation></author><author><name sortKey="Nalls, Michael A" sort="Nalls, Michael A" uniqKey="Nalls M" first="Michael A." last="Nalls">Michael A. Nalls</name><affiliation><nlm:aff id="A62">Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892, USA.</nlm:aff></affiliation></author><author><name sortKey="Palmer, Cameron D" sort="Palmer, Cameron D" uniqKey="Palmer C" first="Cameron D." last="Palmer">Cameron D. Palmer</name><affiliation><nlm:aff id="A5">Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children’s Hospital, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A6">Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.</nlm:aff></affiliation></author><author><name sortKey="Pasko, Dorota" sort="Pasko, Dorota" uniqKey="Pasko D" first="Dorota" last="Pasko">Dorota Pasko</name><affiliation><nlm:aff id="A24">Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK.</nlm:aff></affiliation></author><author><name sortKey="Pechlivanis, Sonali" sort="Pechlivanis, Sonali" uniqKey="Pechlivanis S" first="Sonali" last="Pechlivanis">Sonali Pechlivanis</name><affiliation><nlm:aff id="A63">Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen, 45147 Essen, Germany.</nlm:aff></affiliation></author><author><name sortKey="Peters, Marjolein J" sort="Peters, Marjolein J" uniqKey="Peters M" first="Marjolein J." last="Peters">Marjolein J. Peters</name><affiliation><nlm:aff id="A58">Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A60">Department of Internal Medicine, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Prokopenko, Inga" sort="Prokopenko, Inga" uniqKey="Prokopenko I" first="Inga" last="Prokopenko">Inga Prokopenko</name><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A64">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A65">Department of Genomics of Common Disease, School of Public Health, Imperial College London, Hammersmith Hospital, London W12 0NN, UK.</nlm:aff></affiliation></author><author><name sortKey="Shungin, Dmitry" sort="Shungin, Dmitry" uniqKey="Shungin D" first="Dmitry" last="Shungin">Dmitry Shungin</name><affiliation><nlm:aff id="A66">Department of Clinical Sciences, Genetic & Molecular Epidemiology Unit, Lund University Diabetes Center, Skåne University Hosptial, Malmö 205 02, Sweden.</nlm:aff></affiliation><affiliation><nlm:aff id="A67">Department of Public Health and Clinical Medicine, Unit of Medicine, Umeå University, Umeå 901 87, Sweden.</nlm:aff></affiliation><affiliation><nlm:aff id="A68">Department of Odontology, Umeå University, Umeå 901 85, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Stan Kova, Alena" sort="Stan Kova, Alena" uniqKey="Stan Kova A" first="Alena" last="Stan Ková">Alena Stan Ková</name><affiliation><nlm:aff id="A69">University of Eastern Finland, FI-70210 Kuopio, Finland.</nlm:aff></affiliation></author><author><name sortKey="Strawbridge, Rona J" sort="Strawbridge, Rona J" uniqKey="Strawbridge R" first="Rona J." last="Strawbridge">Rona J. Strawbridge</name><affiliation><nlm:aff id="A70">Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm 17176, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Sung, Yun Ju" sort="Sung, Yun Ju" uniqKey="Sung Y" first="Yun Ju" last="Sung">Yun Ju Sung</name><affiliation><nlm:aff id="A71">Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:aff></affiliation></author><author><name sortKey="Tanaka, Toshiko" sort="Tanaka, Toshiko" uniqKey="Tanaka T" first="Toshiko" last="Tanaka">Toshiko Tanaka</name><affiliation><nlm:aff id="A72">Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland 21225, USA.</nlm:aff></affiliation></author><author><name sortKey="Teumer, Alexander" sort="Teumer, Alexander" uniqKey="Teumer A" first="Alexander" last="Teumer">Alexander Teumer</name><affiliation><nlm:aff id="A73">Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, D-17475 Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Trompet, Stella" sort="Trompet, Stella" uniqKey="Trompet S" first="Stella" last="Trompet">Stella Trompet</name><affiliation><nlm:aff id="A74">Department of Cardiology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A75">Department of Gerontology and Geriatrics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Van Der Laan, Sander W" sort="Van Der Laan, Sander W" uniqKey="Van Der Laan S" first="Sander W." last="Van Der Laan">Sander W. Van Der Laan</name><affiliation><nlm:aff id="A76">Experimental Cardiology Laboratory, Division Heart and Lungs, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Van Setten, Jessica" sort="Van Setten, Jessica" uniqKey="Van Setten J" first="Jessica" last="Van Setten">Jessica Van Setten</name><affiliation><nlm:aff id="A77">Department of Medical Genetics, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Van Vliet Ostaptchouk, Jana V" sort="Van Vliet Ostaptchouk, Jana V" uniqKey="Van Vliet Ostaptchouk J" first="Jana V." last="Van Vliet-Ostaptchouk">Jana V. Van Vliet-Ostaptchouk</name><affiliation><nlm:aff id="A78">Department of Endocrinology, University of Groningen, University Medical Center Groningen, 9700 RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Wang, Zhaoming" sort="Wang, Zhaoming" uniqKey="Wang Z" first="Zhaoming" last="Wang">Zhaoming Wang</name><affiliation><nlm:aff id="A3">Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A79">Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland 21702, USA.</nlm:aff></affiliation></author><author><name sortKey="Yengo, Loic" sort="Yengo, Loic" uniqKey="Yengo L" first="Loïc" last="Yengo">Loïc Yengo</name><affiliation><nlm:aff id="A80">CNRS UMR 8199, F-59019 Lille, France.</nlm:aff></affiliation><affiliation><nlm:aff id="A81">European Genomic Institute for Diabetes, F-59000 Lille, France.</nlm:aff></affiliation><affiliation><nlm:aff id="A82">Université de Lille 2, F-59000 Lille, France.</nlm:aff></affiliation></author><author><name sortKey="Zhang, Weihua" sort="Zhang, Weihua" uniqKey="Zhang W" first="Weihua" last="Zhang">Weihua Zhang</name><affiliation><nlm:aff id="A41">Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A83">Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.</nlm:aff></affiliation></author><author><name sortKey="Isaacs, Aaron" sort="Isaacs, Aaron" uniqKey="Isaacs A" first="Aaron" last="Isaacs">Aaron Isaacs</name><affiliation><nlm:aff id="A32">Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC University Medical Center, 3015 GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A84">Center for Medical Sytems Biology, 2300 RC Leiden, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Albrecht, Eva" sort="Albrecht, Eva" uniqKey="Albrecht E" first="Eva" last="Albrecht">Eva Albrecht</name><affiliation><nlm:aff id="A85">Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.</nlm:aff></affiliation></author><author><name sortKey=" Rnlov, Johan" sort=" Rnlov, Johan" uniqKey=" Rnlov J" first="Johan" last=" Rnlöv">Johan Rnlöv</name><affiliation><nlm:aff id="A16">Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.</nlm:aff></affiliation><affiliation><nlm:aff id="A17">Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala 75185, Sweden.</nlm:aff></affiliation><affiliation><nlm:aff id="A86">School of Health and Social Studies, Dalarna University, SE-791 88 Falun, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Arscott, Gillian M" sort="Arscott, Gillian M" uniqKey="Arscott G" first="Gillian M." last="Arscott">Gillian M. Arscott</name><affiliation><nlm:aff id="A87">PathWest Laboratory Medicine of Western Australia, Nedlands, Western Australia 6009, Australia.</nlm:aff></affiliation></author><author><name sortKey="Attwood, Antony P" sort="Attwood, Antony P" uniqKey="Attwood A" first="Antony P." last="Attwood">Antony P. Attwood</name><affiliation><nlm:aff id="A88">Department of Haematology, University of Cambridge, Cambridge CB2 0PT, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A89">NHS Blood and Transplant, Cambridge CB2 0PT, UK.</nlm:aff></affiliation></author><author><name sortKey="Bandinelli, Stefania" sort="Bandinelli, Stefania" uniqKey="Bandinelli S" first="Stefania" last="Bandinelli">Stefania Bandinelli</name><affiliation><nlm:aff id="A90">Geriatric Unit, Azienda Sanitaria Firenze (ASF), 50125 Florence, Italy.</nlm:aff></affiliation></author><author><name sortKey="Barrett, Amy" sort="Barrett, Amy" uniqKey="Barrett A" first="Amy" last="Barrett">Amy Barrett</name><affiliation><nlm:aff id="A64">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.</nlm:aff></affiliation></author><author><name sortKey="Bas, Isabelita N" sort="Bas, Isabelita N" uniqKey="Bas I" first="Isabelita N." last="Bas">Isabelita N. Bas</name><affiliation><nlm:aff id="A91">USC-Office of Population Studies Foundation, Inc., University of San Carlos, Cebu City 6000, Philippines.</nlm:aff></affiliation></author><author><name sortKey="Bellis, Claire" sort="Bellis, Claire" uniqKey="Bellis C" first="Claire" last="Bellis">Claire Bellis</name><affiliation><nlm:aff id="A92">Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas 78227, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A93">Genomics Research Centre, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland 4001, Australia.</nlm:aff></affiliation></author><author><name sortKey="Bennett, Amanda J" sort="Bennett, Amanda J" uniqKey="Bennett A" first="Amanda J." last="Bennett">Amanda J. Bennett</name><affiliation><nlm:aff id="A64">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.</nlm:aff></affiliation></author><author><name sortKey="Berne, Christian" sort="Berne, Christian" uniqKey="Berne C" first="Christian" last="Berne">Christian Berne</name><affiliation><nlm:aff id="A94">Department of Medical Sciences, Endocrinology, Diabetes and Metabolism, Uppsala University, Uppsala 75185, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Blagieva, Roza" sort="Blagieva, Roza" uniqKey="Blagieva R" first="Roza" last="Blagieva">Roza Blagieva</name><affiliation><nlm:aff id="A95">Division of Endocrinology, Diabetes and Metabolism, Ulm University Medical Centre, D-89081 Ulm, Germany.</nlm:aff></affiliation></author><author><name sortKey="Bluher, Matthias" sort="Bluher, Matthias" uniqKey="Bluher M" first="Matthias" last="Blüher">Matthias Blüher</name><affiliation><nlm:aff id="A96">Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, D-04103 Leipzig, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A97">Department of Medicine, University of Leipzig, D-04103 Leipzig, Germany.</nlm:aff></affiliation></author><author><name sortKey="Bohringer, Stefan" sort="Bohringer, Stefan" uniqKey="Bohringer S" first="Stefan" last="Böhringer">Stefan Böhringer</name><affiliation><nlm:aff id="A34">Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A98">Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Bonnycastle, Lori L" sort="Bonnycastle, Lori L" uniqKey="Bonnycastle L" first="Lori L." last="Bonnycastle">Lori L. Bonnycastle</name><affiliation><nlm:aff id="A99">Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA.</nlm:aff></affiliation></author><author><name sortKey="Bottcher, Yvonne" sort="Bottcher, Yvonne" uniqKey="Bottcher Y" first="Yvonne" last="Böttcher">Yvonne Böttcher</name><affiliation><nlm:aff id="A96">Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, D-04103 Leipzig, Germany.</nlm:aff></affiliation></author><author><name sortKey="Boyd, Heather A" sort="Boyd, Heather A" uniqKey="Boyd H" first="Heather A." last="Boyd">Heather A. Boyd</name><affiliation><nlm:aff id="A46">Department of Epidemiology Research, Statens Serum Institut, Copenhagen DK-2300, Denmark.</nlm:aff></affiliation></author><author><name sortKey="Bruinenberg, Marcel" sort="Bruinenberg, Marcel" uniqKey="Bruinenberg M" first="Marcel" last="Bruinenberg">Marcel Bruinenberg</name><affiliation><nlm:aff id="A100">LifeLines Cohort Study, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Caspersen, Ida H" sort="Caspersen, Ida H" uniqKey="Caspersen I" first="Ida H." last="Caspersen">Ida H. Caspersen</name><affiliation><nlm:aff id="A101">Department of Biology, Norwegian University of Science and Technology, 7491 Trondheim, Norway.</nlm:aff></affiliation></author><author><name sortKey="Chen, Yii Der Ida" sort="Chen, Yii Der Ida" uniqKey="Chen Y" first="Yii-Der Ida" last="Chen">Yii-Der Ida Chen</name><affiliation><nlm:aff id="A102">Department of Pediatrics, University of California Los Angeles, Torrance, California 90502, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A103">Transgenomics Institute, Los Angeles Biomedical Research Institute, Torrance, California 90502, USA.</nlm:aff></affiliation></author><author><name sortKey="Clarke, Robert" sort="Clarke, Robert" uniqKey="Clarke R" first="Robert" last="Clarke">Robert Clarke</name><affiliation><nlm:aff id="A104">Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.</nlm:aff></affiliation></author><author><name sortKey="Daw, E Warwick" sort="Daw, E Warwick" uniqKey="Daw E" first="E. Warwick" last="Daw">E. Warwick Daw</name><affiliation><nlm:aff id="A47">Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:aff></affiliation></author><author><name sortKey="De Craen, Anton J M" sort="De Craen, Anton J M" uniqKey="De Craen A" first="Anton J. M." last="De Craen">Anton J. M. De Craen</name><affiliation><nlm:aff id="A75">Department of Gerontology and Geriatrics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Delgado, Graciela" sort="Delgado, Graciela" uniqKey="Delgado G" first="Graciela" last="Delgado">Graciela Delgado</name><affiliation><nlm:aff id="A51">Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, D-68187 Mannheim, Germany.</nlm:aff></affiliation></author><author><name sortKey="Dimitriou, Maria" sort="Dimitriou, Maria" uniqKey="Dimitriou M" first="Maria" last="Dimitriou">Maria Dimitriou</name><affiliation><nlm:aff id="A105">Department of Dietetics-Nutrition, Harokopio University, 17671 Athens, Greece.</nlm:aff></affiliation></author><author><name sortKey="Doney, Alex S F" sort="Doney, Alex S F" uniqKey="Doney A" first="Alex S. F." last="Doney">Alex S. F. Doney</name><affiliation><nlm:aff id="A106">Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.</nlm:aff></affiliation></author><author><name sortKey="Eklund, Niina" sort="Eklund, Niina" uniqKey="Eklund N" first="Niina" last="Eklund">Niina Eklund</name><affiliation><nlm:aff id="A53">National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A107">Institute for Molecular Medicine, University of Helsinki, FI-00014 Helsinki, Finland.</nlm:aff></affiliation></author><author><name sortKey="Estrada, Karol" sort="Estrada, Karol" uniqKey="Estrada K" first="Karol" last="Estrada">Karol Estrada</name><affiliation><nlm:aff id="A6">Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A60">Department of Internal Medicine, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A108">Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA.</nlm:aff></affiliation></author><author><name sortKey="Eury, Elodie" sort="Eury, Elodie" uniqKey="Eury E" first="Elodie" last="Eury">Elodie Eury</name><affiliation><nlm:aff id="A80">CNRS UMR 8199, F-59019 Lille, France.</nlm:aff></affiliation><affiliation><nlm:aff id="A81">European Genomic Institute for Diabetes, F-59000 Lille, France.</nlm:aff></affiliation><affiliation><nlm:aff id="A82">Université de Lille 2, F-59000 Lille, France.</nlm:aff></affiliation></author><author><name sortKey="Folkersen, Lasse" sort="Folkersen, Lasse" uniqKey="Folkersen L" first="Lasse" last="Folkersen">Lasse Folkersen</name><affiliation><nlm:aff id="A70">Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm 17176, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Fraser, Ross M" sort="Fraser, Ross M" uniqKey="Fraser R" first="Ross M." last="Fraser">Ross M. Fraser</name><affiliation><nlm:aff id="A36">Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK.</nlm:aff></affiliation></author><author><name sortKey="Garcia, Melissa E" sort="Garcia, Melissa E" uniqKey="Garcia M" first="Melissa E." last="Garcia">Melissa E. Garcia</name><affiliation><nlm:aff id="A109">Laboratory of Epidemiology and Population Sciences, National Institute on Aging, NIH, Bethesda, Maryland 20892, USA.</nlm:aff></affiliation></author><author><name sortKey="Geller, Frank" sort="Geller, Frank" uniqKey="Geller F" first="Frank" last="Geller">Frank Geller</name><affiliation><nlm:aff id="A46">Department of Epidemiology Research, Statens Serum Institut, Copenhagen DK-2300, Denmark.</nlm:aff></affiliation></author><author><name sortKey="Giedraitis, Vilmantas" sort="Giedraitis, Vilmantas" uniqKey="Giedraitis V" first="Vilmantas" last="Giedraitis">Vilmantas Giedraitis</name><affiliation><nlm:aff id="A110">Department of Public Health and Caring Sciences, Geriatrics, Uppsala University, Uppsala 75185, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Gigante, Bruna" sort="Gigante, Bruna" uniqKey="Gigante B" first="Bruna" last="Gigante">Bruna Gigante</name><affiliation><nlm:aff id="A111">Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, Stockholm 17177, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Go, Alan S" sort="Go, Alan S" uniqKey="Go A" first="Alan S." last="Go">Alan S. Go</name><affiliation><nlm:aff id="A112">Kaiser Permanente, Division of Research, Oakland, California 94612, USA.</nlm:aff></affiliation></author><author><name sortKey="Golay, Alain" sort="Golay, Alain" uniqKey="Golay A" first="Alain" last="Golay">Alain Golay</name><affiliation><nlm:aff id="A113">Service of Therapeutic Education for Diabetes, Obesity and Chronic Diseases, Geneva University Hospital, Geneva CH-1211, Switzerland.</nlm:aff></affiliation></author><author><name sortKey="Goodall, Alison H" sort="Goodall, Alison H" uniqKey="Goodall A" first="Alison H." last="Goodall">Alison H. Goodall</name><affiliation><nlm:aff id="A114">Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester LE3 9QP, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A115">National Institute for Health Research (NIHR) Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester LE3 9QP, UK.</nlm:aff></affiliation></author><author><name sortKey="Gordon, Scott D" sort="Gordon, Scott D" uniqKey="Gordon S" first="Scott D." last="Gordon">Scott D. Gordon</name><affiliation><nlm:aff id="A61">QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4006, Australia.</nlm:aff></affiliation></author><author><name sortKey="Gorski, Mathias" sort="Gorski, Mathias" uniqKey="Gorski M" first="Mathias" last="Gorski">Mathias Gorski</name><affiliation><nlm:aff id="A23">Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, D-93053 Regensburg, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A116">Department of Nephrology, University Hospital Regensburg, D-93053 Regensburg, Germany.</nlm:aff></affiliation></author><author><name sortKey="Grabe, Hans Jorgen" sort="Grabe, Hans Jorgen" uniqKey="Grabe H" first="Hans-Jörgen" last="Grabe">Hans-Jörgen Grabe</name><affiliation><nlm:aff id="A117">Department of Psychiatry and Psychotherapy, University Medicine Greifswald, HELIOS-Hospital Stralsund, D-17475 Greifswald, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A118">German Center for Neurodegenerative Diseases (DZNE), Rostock, Greifswald, D-17475 Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Grallert, Harald" sort="Grallert, Harald" uniqKey="Grallert H" first="Harald" last="Grallert">Harald Grallert</name><affiliation><nlm:aff id="A85">Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A119">Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A120">German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany.</nlm:aff></affiliation></author><author><name sortKey="Grammer, Tanja B" sort="Grammer, Tanja B" uniqKey="Grammer T" first="Tanja B." last="Grammer">Tanja B. Grammer</name><affiliation><nlm:aff id="A51">Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, D-68187 Mannheim, Germany.</nlm:aff></affiliation></author><author><name sortKey="Gr Ler, Jurgen" sort="Gr Ler, Jurgen" uniqKey="Gr Ler J" first="Jürgen" last="Gr Ler">Jürgen Gr Ler</name><affiliation><nlm:aff id="A121">Department of Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, D-01307 Dresden, Germany.</nlm:aff></affiliation></author><author><name sortKey="Gronberg, Henrik" sort="Gronberg, Henrik" uniqKey="Gronberg H" first="Henrik" last="Grönberg">Henrik Grönberg</name><affiliation><nlm:aff id="A15">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Groves, Christopher J" sort="Groves, Christopher J" uniqKey="Groves C" first="Christopher J." last="Groves">Christopher J. Groves</name><affiliation><nlm:aff id="A64">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.</nlm:aff></affiliation></author><author><name sortKey="Gusto, Gaelle" sort="Gusto, Gaelle" uniqKey="Gusto G" first="Gaëlle" last="Gusto">Gaëlle Gusto</name><affiliation><nlm:aff id="A122">Institut inter Régional pour la Santé, Synergies, F-37520 La Riche, France.</nlm:aff></affiliation></author><author><name sortKey="Haessler, Jeffrey" sort="Haessler, Jeffrey" uniqKey="Haessler J" first="Jeffrey" last="Haessler">Jeffrey Haessler</name><affiliation><nlm:aff id="A49">Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.</nlm:aff></affiliation></author><author><name sortKey="Hall, Per" sort="Hall, Per" uniqKey="Hall P" first="Per" last="Hall">Per Hall</name><affiliation><nlm:aff id="A15">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Haller, Toomas" sort="Haller, Toomas" uniqKey="Haller T" first="Toomas" last="Haller">Toomas Haller</name><affiliation><nlm:aff id="A14">Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.</nlm:aff></affiliation></author><author><name sortKey="Hallmans, Goran" sort="Hallmans, Goran" uniqKey="Hallmans G" first="Goran" last="Hallmans">Goran Hallmans</name><affiliation><nlm:aff id="A123">Department of Public Health and Clinical Medicine, Unit of Nutritional Research, Umeå University, Umeå 90187, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Hartman, Catharina A" sort="Hartman, Catharina A" uniqKey="Hartman C" first="Catharina A." last="Hartman">Catharina A. Hartman</name><affiliation><nlm:aff id="A124">Department of Psychiatry, University of Groningen, University Medical Center Groningen, 9700RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Hassinen, Maija" sort="Hassinen, Maija" uniqKey="Hassinen M" first="Maija" last="Hassinen">Maija Hassinen</name><affiliation><nlm:aff id="A125">Kuopio Research Institute of Exercise Medicine, 70100 Kuopio, Finland.</nlm:aff></affiliation></author><author><name sortKey="Hayward, Caroline" sort="Hayward, Caroline" uniqKey="Hayward C" first="Caroline" last="Hayward">Caroline Hayward</name><affiliation><nlm:aff id="A126">MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK.</nlm:aff></affiliation></author><author><name sortKey="Heard Costa, Nancy L" sort="Heard Costa, Nancy L" uniqKey="Heard Costa N" first="Nancy L." last="Heard-Costa">Nancy L. Heard-Costa</name><affiliation><nlm:aff id="A127">National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts 01702, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A128">Department of Neurology, Boston University School of Medicine, Boston, Massachusetts 02118, USA.</nlm:aff></affiliation></author><author><name sortKey="Helmer, Quinta" sort="Helmer, Quinta" uniqKey="Helmer Q" first="Quinta" last="Helmer">Quinta Helmer</name><affiliation><nlm:aff id="A34">Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A98">Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A129">Faculty of Psychology and Education, VU University Amsterdam, 1081BT Amsterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Hengstenberg, Christian" sort="Hengstenberg, Christian" uniqKey="Hengstenberg C" first="Christian" last="Hengstenberg">Christian Hengstenberg</name><affiliation><nlm:aff id="A130">Deutsches Forschungszentrum für Herz-Kreislauferkrankungen (DZHK) (German Research Centre for Cardiovascular Research), Munich Heart Alliance, D-80636 Munich, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A131">Deutsches Herzzentrum München, Technische Universität München, D-80636 Munich, Germany.</nlm:aff></affiliation></author><author><name sortKey="Holmen, Oddgeir" sort="Holmen, Oddgeir" uniqKey="Holmen O" first="Oddgeir" last="Holmen">Oddgeir Holmen</name><affiliation><nlm:aff id="A132">Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim 7489, Norway.</nlm:aff></affiliation></author><author><name sortKey="Hottenga, Jouke Jan" sort="Hottenga, Jouke Jan" uniqKey="Hottenga J" first="Jouke-Jan" last="Hottenga">Jouke-Jan Hottenga</name><affiliation><nlm:aff id="A133">Biological Psychology, VU University Amsterdam, 1081BT Amsterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="James, Alan L" sort="James, Alan L" uniqKey="James A" first="Alan L." last="James">Alan L. James</name><affiliation><nlm:aff id="A134">Department of Pulmonary Physiology and Sleep Medicine, Nedlands, Western Australia 6009, Australia.</nlm:aff></affiliation><affiliation><nlm:aff id="A135">School of Medicine and Pharmacology, University of Western Australia, Crawley 6009, Australia.</nlm:aff></affiliation></author><author><name sortKey="Jeff, Janina M" sort="Jeff, Janina M" uniqKey="Jeff J" first="Janina M." last="Jeff">Janina M. Jeff</name><affiliation><nlm:aff id="A55">The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:aff></affiliation></author><author><name sortKey="Johansson, Sa" sort="Johansson, Sa" uniqKey="Johansson " first=" Sa" last="Johansson"> Sa Johansson</name><affiliation><nlm:aff id="A136">Uppsala University, Department of Immunology, Genetics, Pathology, SciLifeLab, Rudbeck Laboratory, SE-751 85 Uppsala, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Jolley, Jennifer" sort="Jolley, Jennifer" uniqKey="Jolley J" first="Jennifer" last="Jolley">Jennifer Jolley</name><affiliation><nlm:aff id="A88">Department of Haematology, University of Cambridge, Cambridge CB2 0PT, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A89">NHS Blood and Transplant, Cambridge CB2 0PT, UK.</nlm:aff></affiliation></author><author><name sortKey="Juliusdottir, Thorhildur" sort="Juliusdottir, Thorhildur" uniqKey="Juliusdottir T" first="Thorhildur" last="Juliusdottir">Thorhildur Juliusdottir</name><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation></author><author><name sortKey="Kinnunen, Leena" sort="Kinnunen, Leena" uniqKey="Kinnunen L" first="Leena" last="Kinnunen">Leena Kinnunen</name><affiliation><nlm:aff id="A53">National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:aff></affiliation></author><author><name sortKey="Koenig, Wolfgang" sort="Koenig, Wolfgang" uniqKey="Koenig W" first="Wolfgang" last="Koenig">Wolfgang Koenig</name><affiliation><nlm:aff id="A52">Department of Internal Medicine II, Ulm University Medical Centre, D-89081 Ulm, Germany.</nlm:aff></affiliation></author><author><name sortKey="Koskenvuo, Markku" sort="Koskenvuo, Markku" uniqKey="Koskenvuo M" first="Markku" last="Koskenvuo">Markku Koskenvuo</name><affiliation><nlm:aff id="A137">Hjelt Institute Department of Public Health, University of Helsinki, FI-00014 Helsinki, Finland.</nlm:aff></affiliation></author><author><name sortKey="Kratzer, Wolfgang" sort="Kratzer, Wolfgang" uniqKey="Kratzer W" first="Wolfgang" last="Kratzer">Wolfgang Kratzer</name><affiliation><nlm:aff id="A138">Department of Internal Medicine I, Ulm University Medical Centre, D-89081 Ulm, Germany.</nlm:aff></affiliation></author><author><name sortKey="Laitinen, Jaana" sort="Laitinen, Jaana" uniqKey="Laitinen J" first="Jaana" last="Laitinen">Jaana Laitinen</name><affiliation><nlm:aff id="A139">Finnish Institute of Occupational Health, FI-90100 Oulu, Finland.</nlm:aff></affiliation></author><author><name sortKey="Lamina, Claudia" sort="Lamina, Claudia" uniqKey="Lamina C" first="Claudia" last="Lamina">Claudia Lamina</name><affiliation><nlm:aff id="A140">Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, 6020 Innsbruck, Austria.</nlm:aff></affiliation></author><author><name sortKey="Leander, Karin" sort="Leander, Karin" uniqKey="Leander K" first="Karin" last="Leander">Karin Leander</name><affiliation><nlm:aff id="A111">Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, Stockholm 17177, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Lee, Nanette R" sort="Lee, Nanette R" uniqKey="Lee N" first="Nanette R." last="Lee">Nanette R. Lee</name><affiliation><nlm:aff id="A91">USC-Office of Population Studies Foundation, Inc., University of San Carlos, Cebu City 6000, Philippines.</nlm:aff></affiliation></author><author><name sortKey="Lichtner, Peter" sort="Lichtner, Peter" uniqKey="Lichtner P" first="Peter" last="Lichtner">Peter Lichtner</name><affiliation><nlm:aff id="A141">Institute of Human Genetics, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.</nlm:aff></affiliation></author><author><name sortKey="Lind, Lars" sort="Lind, Lars" uniqKey="Lind L" first="Lars" last="Lind">Lars Lind</name><affiliation><nlm:aff id="A142">Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala 75185, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Lindstrom, Jaana" sort="Lindstrom, Jaana" uniqKey="Lindstrom J" first="Jaana" last="Lindström">Jaana Lindström</name><affiliation><nlm:aff id="A53">National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:aff></affiliation></author><author><name sortKey="Lo, Ken Sin" sort="Lo, Ken Sin" uniqKey="Lo K" first="Ken Sin" last="Lo">Ken Sin Lo</name><affiliation><nlm:aff id="A143">Montreal Heart Institute, Montreal, Quebec H1T 1C8, Canada.</nlm:aff></affiliation></author><author><name sortKey="Lobbens, Stephane" sort="Lobbens, Stephane" uniqKey="Lobbens S" first="Stéphane" last="Lobbens">Stéphane Lobbens</name><affiliation><nlm:aff id="A80">CNRS UMR 8199, F-59019 Lille, France.</nlm:aff></affiliation><affiliation><nlm:aff id="A81">European Genomic Institute for Diabetes, F-59000 Lille, France.</nlm:aff></affiliation><affiliation><nlm:aff id="A82">Université de Lille 2, F-59000 Lille, France.</nlm:aff></affiliation></author><author><name sortKey="Lorbeer, Roberto" sort="Lorbeer, Roberto" uniqKey="Lorbeer R" first="Roberto" last="Lorbeer">Roberto Lorbeer</name><affiliation><nlm:aff id="A144">Institute for Community Medicine, University Medicine Greifswald, D-17475 Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Lu, Yingchang" sort="Lu, Yingchang" uniqKey="Lu Y" first="Yingchang" last="Lu">Yingchang Lu</name><affiliation><nlm:aff id="A55">The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A145">The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:aff></affiliation></author><author><name sortKey="Mach, Francois" sort="Mach, Francois" uniqKey="Mach F" first="François" last="Mach">François Mach</name><affiliation><nlm:aff id="A45">Cardiology, Department of Specialties of Internal Medicine, Geneva University Hospital, Geneva 1211, Switzerland.</nlm:aff></affiliation></author><author><name sortKey="Magnusson, Patrik K E" sort="Magnusson, Patrik K E" uniqKey="Magnusson P" first="Patrik K. E." last="Magnusson">Patrik K. E. Magnusson</name><affiliation><nlm:aff id="A15">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Mahajan, Anubha" sort="Mahajan, Anubha" uniqKey="Mahajan A" first="Anubha" last="Mahajan">Anubha Mahajan</name><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation></author><author><name sortKey="Mcardle, Wendy L" sort="Mcardle, Wendy L" uniqKey="Mcardle W" first="Wendy L." last="Mcardle">Wendy L. Mcardle</name><affiliation><nlm:aff id="A146">School of Social and Community Medicine, University of Bristol, Bristol BS8 2BN, UK.</nlm:aff></affiliation></author><author><name sortKey="Mclachlan, Stela" sort="Mclachlan, Stela" uniqKey="Mclachlan S" first="Stela" last="Mclachlan">Stela Mclachlan</name><affiliation><nlm:aff id="A36">Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK.</nlm:aff></affiliation></author><author><name sortKey="Menni, Cristina" sort="Menni, Cristina" uniqKey="Menni C" first="Cristina" last="Menni">Cristina Menni</name><affiliation><nlm:aff id="A56">Department of Twin Research and Genetic Epidemiology, King’s College London, London SE1 7EH, UK.</nlm:aff></affiliation></author><author><name sortKey="Merger, Sigrun" sort="Merger, Sigrun" uniqKey="Merger S" first="Sigrun" last="Merger">Sigrun Merger</name><affiliation><nlm:aff id="A95">Division of Endocrinology, Diabetes and Metabolism, Ulm University Medical Centre, D-89081 Ulm, Germany.</nlm:aff></affiliation></author><author><name sortKey="Mihailov, Evelin" sort="Mihailov, Evelin" uniqKey="Mihailov E" first="Evelin" last="Mihailov">Evelin Mihailov</name><affiliation><nlm:aff id="A14">Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.</nlm:aff></affiliation><affiliation><nlm:aff id="A147">Institute of Molecular and Cell Biology, University of Tartu, Tartu 51010, Estonia.</nlm:aff></affiliation></author><author><name sortKey="Milani, Lili" sort="Milani, Lili" uniqKey="Milani L" first="Lili" last="Milani">Lili Milani</name><affiliation><nlm:aff id="A14">Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.</nlm:aff></affiliation></author><author><name sortKey="Moayyeri, Alireza" sort="Moayyeri, Alireza" uniqKey="Moayyeri A" first="Alireza" last="Moayyeri">Alireza Moayyeri</name><affiliation><nlm:aff id="A56">Department of Twin Research and Genetic Epidemiology, King’s College London, London SE1 7EH, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A148">Farr Institute of Health Informatics Research, University College London, London NW1 2DA, UK.</nlm:aff></affiliation></author><author><name sortKey="Monda, Keri L" sort="Monda, Keri L" uniqKey="Monda K" first="Keri L." last="Monda">Keri L. Monda</name><affiliation><nlm:aff id="A4">Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A149">The Center for Observational Research, Amgen, Inc., Thousand Oaks, California 91320, USA.</nlm:aff></affiliation></author><author><name sortKey="Morken, Mario A" sort="Morken, Mario A" uniqKey="Morken M" first="Mario A." last="Morken">Mario A. Morken</name><affiliation><nlm:aff id="A99">Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA.</nlm:aff></affiliation></author><author><name sortKey="Mulas, Antonella" sort="Mulas, Antonella" uniqKey="Mulas A" first="Antonella" last="Mulas">Antonella Mulas</name><affiliation><nlm:aff id="A150">Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche, Cagliari, Sardinia 09042, Italy.</nlm:aff></affiliation></author><author><name sortKey="Muller, Gabriele" sort="Muller, Gabriele" uniqKey="Muller G" first="Gabriele" last="Müller">Gabriele Müller</name><affiliation><nlm:aff id="A151">Center for Evidence-based Healthcare, University Hospital Carl Gustav Carus, Technische Universität Dresden, D-01307 Dresden, Germany.</nlm:aff></affiliation></author><author><name sortKey="Muller Nurasyid, Martina" sort="Muller Nurasyid, Martina" uniqKey="Muller Nurasyid M" first="Martina" last="Müller-Nurasyid">Martina Müller-Nurasyid</name><affiliation><nlm:aff id="A85">Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A130">Deutsches Forschungszentrum für Herz-Kreislauferkrankungen (DZHK) (German Research Centre for Cardiovascular Research), Munich Heart Alliance, D-80636 Munich, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A152">Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität, D-81377 Munich, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A153">Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, D-81377 Munich, Germany.</nlm:aff></affiliation></author><author><name sortKey="Musk, Arthur W" sort="Musk, Arthur W" uniqKey="Musk A" first="Arthur W." last="Musk">Arthur W. Musk</name><affiliation><nlm:aff id="A154">Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia 6009, Australia.</nlm:aff></affiliation></author><author><name sortKey="Nagaraja, Ramaiah" sort="Nagaraja, Ramaiah" uniqKey="Nagaraja R" first="Ramaiah" last="Nagaraja">Ramaiah Nagaraja</name><affiliation><nlm:aff id="A155">Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland 21224, USA.</nlm:aff></affiliation></author><author><name sortKey="Nothen, Markus M" sort="Nothen, Markus M" uniqKey="Nothen M" first="Markus M." last="Nöthen">Markus M. Nöthen</name><affiliation><nlm:aff id="A156">Department of Genomics, Life & Brain Center, University of Bonn, 53127 Bonn, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A157">Institute of Human Genetics, University of Bonn, 53127 Bonn, Germany.</nlm:aff></affiliation></author><author><name sortKey="Nolte, Ilja M" sort="Nolte, Ilja M" uniqKey="Nolte I" first="Ilja M." last="Nolte">Ilja M. Nolte</name><affiliation><nlm:aff id="A158">Department of Epidemiology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Pilz, Stefan" sort="Pilz, Stefan" uniqKey="Pilz S" first="Stefan" last="Pilz">Stefan Pilz</name><affiliation><nlm:aff id="A159">Department of Epidemiology and Biostatistics, Institute for Research in Extramural Medicine, Institute for Health and Care Research, VU University Medical Center, 1081BT Amsterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A160">Department of Internal Medicine, Division of Endocrinology and Metabolism, Medical University of Graz, 8036 Graz, Austria.</nlm:aff></affiliation></author><author><name sortKey="Rayner, Nigel W" sort="Rayner, Nigel W" uniqKey="Rayner N" first="Nigel W." last="Rayner">Nigel W. Rayner</name><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A22">Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A64">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.</nlm:aff></affiliation></author><author><name sortKey="Renstrom, Frida" sort="Renstrom, Frida" uniqKey="Renstrom F" first="Frida" last="Renstrom">Frida Renstrom</name><affiliation><nlm:aff id="A66">Department of Clinical Sciences, Genetic & Molecular Epidemiology Unit, Lund University Diabetes Center, Skåne University Hosptial, Malmö 205 02, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Rettig, Rainer" sort="Rettig, Rainer" uniqKey="Rettig R" first="Rainer" last="Rettig">Rainer Rettig</name><affiliation><nlm:aff id="A161">Institute of Physiology, University Medicine Greifswald, D-17495 Karlsburg, Germany.</nlm:aff></affiliation></author><author><name sortKey="Ried, Janina S" sort="Ried, Janina S" uniqKey="Ried J" first="Janina S." last="Ried">Janina S. Ried</name><affiliation><nlm:aff id="A85">Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.</nlm:aff></affiliation></author><author><name sortKey="Ripke, Stephan" sort="Ripke, Stephan" uniqKey="Ripke S" first="Stephan" last="Ripke">Stephan Ripke</name><affiliation><nlm:aff id="A108">Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A162">Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.</nlm:aff></affiliation></author><author><name sortKey="Robertson, Neil R" sort="Robertson, Neil R" uniqKey="Robertson N" first="Neil R." last="Robertson">Neil R. Robertson</name><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A64">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.</nlm:aff></affiliation></author><author><name sortKey="Rose, Lynda M" sort="Rose, Lynda M" uniqKey="Rose L" first="Lynda M." last="Rose">Lynda M. Rose</name><affiliation><nlm:aff id="A163">Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, Massachusetts 02215, USA.</nlm:aff></affiliation></author><author><name sortKey="Sanna, Serena" sort="Sanna, Serena" uniqKey="Sanna S" first="Serena" last="Sanna">Serena Sanna</name><affiliation><nlm:aff id="A150">Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche, Cagliari, Sardinia 09042, Italy.</nlm:aff></affiliation></author><author><name sortKey="Scharnagl, Hubert" sort="Scharnagl, Hubert" uniqKey="Scharnagl H" first="Hubert" last="Scharnagl">Hubert Scharnagl</name><affiliation><nlm:aff id="A164">Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz 8036, Austria.</nlm:aff></affiliation></author><author><name sortKey="Scholtens, Salome" sort="Scholtens, Salome" uniqKey="Scholtens S" first="Salome" last="Scholtens">Salome Scholtens</name><affiliation><nlm:aff id="A100">LifeLines Cohort Study, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Schumacher, Fredrick R" sort="Schumacher, Fredrick R" uniqKey="Schumacher F" first="Fredrick R." last="Schumacher">Fredrick R. Schumacher</name><affiliation><nlm:aff id="A165">Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA.</nlm:aff></affiliation></author><author><name sortKey="Scott, William R" sort="Scott, William R" uniqKey="Scott W" first="William R." last="Scott">William R. Scott</name><affiliation><nlm:aff id="A41">Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A83">Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.</nlm:aff></affiliation></author><author><name sortKey="Seufferlein, Thomas" sort="Seufferlein, Thomas" uniqKey="Seufferlein T" first="Thomas" last="Seufferlein">Thomas Seufferlein</name><affiliation><nlm:aff id="A138">Department of Internal Medicine I, Ulm University Medical Centre, D-89081 Ulm, Germany.</nlm:aff></affiliation></author><author><name sortKey="Shi, Jianxin" sort="Shi, Jianxin" uniqKey="Shi J" first="Jianxin" last="Shi">Jianxin Shi</name><affiliation><nlm:aff id="A166">National Cancer Institute, Bethesda, Maryland 20892, USA.</nlm:aff></affiliation></author><author><name sortKey="Smith, Albert Vernon" sort="Smith, Albert Vernon" uniqKey="Smith A" first="Albert Vernon" last="Smith">Albert Vernon Smith</name><affiliation><nlm:aff id="A167">Icelandic Heart Association, Kopavogur 201, Iceland.</nlm:aff></affiliation><affiliation><nlm:aff id="A168">University of Iceland, Reykjavik 101, Iceland.</nlm:aff></affiliation></author><author><name sortKey="Smolonska, Joanna" sort="Smolonska, Joanna" uniqKey="Smolonska J" first="Joanna" last="Smolonska">Joanna Smolonska</name><affiliation><nlm:aff id="A29">Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A169">Department of Epidemiology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Stanton, Alice V" sort="Stanton, Alice V" uniqKey="Stanton A" first="Alice V." last="Stanton">Alice V. Stanton</name><affiliation><nlm:aff id="A170">Molecular & Cellular Therapeutics, Royal College of Surgeons in Ireland, 123 St Stephen’s Green, Dublin 2, Ireland.</nlm:aff></affiliation></author><author><name sortKey="Steinthorsdottir, Valgerdur" sort="Steinthorsdottir, Valgerdur" uniqKey="Steinthorsdottir V" first="Valgerdur" last="Steinthorsdottir">Valgerdur Steinthorsdottir</name><affiliation><nlm:aff id="A171">deCODE Genetics, Amgen Inc., Reykjavik 101, Iceland.</nlm:aff></affiliation></author><author><name sortKey="Stirrups, Kathleen" sort="Stirrups, Kathleen" uniqKey="Stirrups K" first="Kathleen" last="Stirrups">Kathleen Stirrups</name><affiliation><nlm:aff id="A22">Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A50">William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.</nlm:aff></affiliation></author><author><name sortKey="Stringham, Heather M" sort="Stringham, Heather M" uniqKey="Stringham H" first="Heather M." last="Stringham">Heather M. Stringham</name><affiliation><nlm:aff id="A1">Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation></author><author><name sortKey="Sundstrom, Johan" sort="Sundstrom, Johan" uniqKey="Sundstrom J" first="Johan" last="Sundström">Johan Sundström</name><affiliation><nlm:aff id="A142">Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala 75185, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Swertz, Morris A" sort="Swertz, Morris A" uniqKey="Swertz M" first="Morris A." last="Swertz">Morris A. Swertz</name><affiliation><nlm:aff id="A29">Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Swift, Amy J" sort="Swift, Amy J" uniqKey="Swift A" first="Amy J." last="Swift">Amy J. Swift</name><affiliation><nlm:aff id="A99">Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA.</nlm:aff></affiliation></author><author><name sortKey="Syv Nen, Ann Christine" sort="Syv Nen, Ann Christine" uniqKey="Syv Nen A" first="Ann-Christine" last="Syv Nen">Ann-Christine Syv Nen</name><affiliation><nlm:aff id="A16">Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.</nlm:aff></affiliation><affiliation><nlm:aff id="A172">Department of Medical Sciences, Molecular Medicine, Uppsala University, Uppsala 75144, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Tan, Sian Tsung" sort="Tan, Sian Tsung" uniqKey="Tan S" first="Sian-Tsung" last="Tan">Sian-Tsung Tan</name><affiliation><nlm:aff id="A41">Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A173">National Heart and Lung Institute, Imperial College London, London SW3 6LY, UK.</nlm:aff></affiliation></author><author><name sortKey="Tayo, Bamidele O" sort="Tayo, Bamidele O" uniqKey="Tayo B" first="Bamidele O." last="Tayo">Bamidele O. Tayo</name><affiliation><nlm:aff id="A174">Department of Public Health Sciences, Stritch School of Medicine, Loyola University of Chicago, Maywood, Illinois 61053, USA.</nlm:aff></affiliation></author><author><name sortKey="Thorand, Barbara" sort="Thorand, Barbara" uniqKey="Thorand B" first="Barbara" last="Thorand">Barbara Thorand</name><affiliation><nlm:aff id="A120">German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A175">Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany, D-85764 Neuherberg, Germany.</nlm:aff></affiliation></author><author><name sortKey="Thorleifsson, Gudmar" sort="Thorleifsson, Gudmar" uniqKey="Thorleifsson G" first="Gudmar" last="Thorleifsson">Gudmar Thorleifsson</name><affiliation><nlm:aff id="A171">deCODE Genetics, Amgen Inc., Reykjavik 101, Iceland.</nlm:aff></affiliation></author><author><name sortKey="Tyrer, Jonathan P" sort="Tyrer, Jonathan P" uniqKey="Tyrer J" first="Jonathan P." last="Tyrer">Jonathan P. Tyrer</name><affiliation><nlm:aff id="A176">Department of Oncology, University of Cambridge, Cambridge CB2 0QQ, UK.</nlm:aff></affiliation></author><author><name sortKey="Uh, Hae Won" sort="Uh, Hae Won" uniqKey="Uh H" first="Hae-Won" last="Uh">Hae-Won Uh</name><affiliation><nlm:aff id="A34">Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A98">Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Vandenput, Liesbeth" sort="Vandenput, Liesbeth" uniqKey="Vandenput L" first="Liesbeth" last="Vandenput">Liesbeth Vandenput</name><affiliation><nlm:aff id="A177">Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg 413 45, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Verhulst, Frank C" sort="Verhulst, Frank C" uniqKey="Verhulst F" first="Frank C." last="Verhulst">Frank C. Verhulst</name><affiliation><nlm:aff id="A178">Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC University Medical Centre, 3000 CB Rotterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Vermeulen, Sita H" sort="Vermeulen, Sita H" uniqKey="Vermeulen S" first="Sita H." last="Vermeulen">Sita H. Vermeulen</name><affiliation><nlm:aff id="A179">Department for Health Evidence, Radboud University Medical Centre, 6500 HB Nijmegen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A180">Department of Genetics, Radboud University Medical Centre, 6500 HB Nijmegen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Verweij, Niek" sort="Verweij, Niek" uniqKey="Verweij N" first="Niek" last="Verweij">Niek Verweij</name><affiliation><nlm:aff id="A57">Department of Cardiology, University Medical Center Groningen, University of Groningen, 9700RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Vonk, Judith M" sort="Vonk, Judith M" uniqKey="Vonk J" first="Judith M." last="Vonk">Judith M. Vonk</name><affiliation><nlm:aff id="A169">Department of Epidemiology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Waite, Lindsay L" sort="Waite, Lindsay L" uniqKey="Waite L" first="Lindsay L." last="Waite">Lindsay L. Waite</name><affiliation><nlm:aff id="A31">HudsonAlpha Institute for Biotechnology, Huntsville, Alabama 35806, USA.</nlm:aff></affiliation></author><author><name sortKey="Warren, Helen R" sort="Warren, Helen R" uniqKey="Warren H" first="Helen R." last="Warren">Helen R. Warren</name><affiliation><nlm:aff id="A181">Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.</nlm:aff></affiliation></author><author><name sortKey="Waterworth, Dawn" sort="Waterworth, Dawn" uniqKey="Waterworth D" first="Dawn" last="Waterworth">Dawn Waterworth</name><affiliation><nlm:aff id="A182">Genetics, GlaxoSmithKline, King of Prussia, Pennsylvania 19406, USA.</nlm:aff></affiliation></author><author><name sortKey="Weedon, Michael N" sort="Weedon, Michael N" uniqKey="Weedon M" first="Michael N." last="Weedon">Michael N. Weedon</name><affiliation><nlm:aff id="A24">Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK.</nlm:aff></affiliation></author><author><name sortKey="Wilkens, Lynne R" sort="Wilkens, Lynne R" uniqKey="Wilkens L" first="Lynne R." last="Wilkens">Lynne R. Wilkens</name><affiliation><nlm:aff id="A54">Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96813, USA.</nlm:aff></affiliation></author><author><name sortKey="Willenborg, Christina" sort="Willenborg, Christina" uniqKey="Willenborg C" first="Christina" last="Willenborg">Christina Willenborg</name><affiliation><nlm:aff id="A183">German Center for Cardiovascular Research, partner site Hamburg/Lubeck/Kiel, 23562 Lubeck, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A184">Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, D-23562 Lübeck, Germany.</nlm:aff></affiliation></author><author><name sortKey="Wilsgaard, Tom" sort="Wilsgaard, Tom" uniqKey="Wilsgaard T" first="Tom" last="Wilsgaard">Tom Wilsgaard</name><affiliation><nlm:aff id="A185">Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, 9037 Tromsø, Norway.</nlm:aff></affiliation></author><author><name sortKey="Wojczynski, Mary K" sort="Wojczynski, Mary K" uniqKey="Wojczynski M" first="Mary K." last="Wojczynski">Mary K. Wojczynski</name><affiliation><nlm:aff id="A47">Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:aff></affiliation></author><author><name sortKey="Wong, Andrew" sort="Wong, Andrew" uniqKey="Wong A" first="Andrew" last="Wong">Andrew Wong</name><affiliation><nlm:aff id="A186">MRC Unit for Lifelong Health and Ageing at University College London, London WC1B 5JU, UK.</nlm:aff></affiliation></author><author><name sortKey="Wright, Alan F" sort="Wright, Alan F" uniqKey="Wright A" first="Alan F." last="Wright">Alan F. Wright</name><affiliation><nlm:aff id="A126">MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK.</nlm:aff></affiliation></author><author><name sortKey="Zhang, Qunyuan" sort="Zhang, Qunyuan" uniqKey="Zhang Q" first="Qunyuan" last="Zhang">Qunyuan Zhang</name><affiliation><nlm:aff id="A47">Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:aff></affiliation></author><author><name sortKey="Brennan, Eoin P" sort="Brennan, Eoin P" uniqKey="Brennan E" first="Eoin P." last="Brennan">Eoin P. Brennan</name><affiliation><nlm:aff id="A187">Diabetes Complications Research Centre, Conway Institute, School of Medicine and Medical Sciences, University College Dublin, Dublin 4, Ireland.</nlm:aff></affiliation></author><author><name sortKey="Choi, Murim" sort="Choi, Murim" uniqKey="Choi M" first="Murim" last="Choi">Murim Choi</name><affiliation><nlm:aff id="A188">Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea.</nlm:aff></affiliation></author><author><name sortKey="Dastani, Zari" sort="Dastani, Zari" uniqKey="Dastani Z" first="Zari" last="Dastani">Zari Dastani</name><affiliation><nlm:aff id="A189">Lady Davis Institute, Departments of Human Genetics, Epidemiology and Biostatistics, McGill University, Montréal, Québec H3T1E2, Canada.</nlm:aff></affiliation></author><author><name sortKey="Drong, Alexander W" sort="Drong, Alexander W" uniqKey="Drong A" first="Alexander W." last="Drong">Alexander W. Drong</name><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation></author><author><name sortKey="Eriksson, Per" sort="Eriksson, Per" uniqKey="Eriksson P" first="Per" last="Eriksson">Per Eriksson</name><affiliation><nlm:aff id="A70">Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm 17176, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Franco Cereceda, Anders" sort="Franco Cereceda, Anders" uniqKey="Franco Cereceda A" first="Anders" last="Franco-Cereceda">Anders Franco-Cereceda</name><affiliation><nlm:aff id="A190">Cardiothoracic Surgery Unit, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm 17176, Sweden.</nlm:aff></affiliation></author><author><name sortKey="G Din, Jesper R" sort="G Din, Jesper R" uniqKey="G Din J" first="Jesper R." last="G Din">Jesper R. G Din</name><affiliation><nlm:aff id="A70">Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm 17176, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Gharavi, Ali G" sort="Gharavi, Ali G" uniqKey="Gharavi A" first="Ali G." last="Gharavi">Ali G. Gharavi</name><affiliation><nlm:aff id="A191">Department of Medicine, Columbia University College of Physicians and Surgeons, New York 10032, USA.</nlm:aff></affiliation></author><author><name sortKey="Goddard, Michael E" sort="Goddard, Michael E" uniqKey="Goddard M" first="Michael E." last="Goddard">Michael E. Goddard</name><affiliation><nlm:aff id="A192">Biosciences Research Division, Department of Primary Industries, Victoria 3083, Australia.</nlm:aff></affiliation><affiliation><nlm:aff id="A193">Department of Food and Agricultural Systems, University of Melbourne, Victoria 3010, Australia.</nlm:aff></affiliation></author><author><name sortKey="Handsaker, Robert E" sort="Handsaker, Robert E" uniqKey="Handsaker R" first="Robert E." last="Handsaker">Robert E. Handsaker</name><affiliation><nlm:aff id="A6">Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A7">Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation></author><author><name sortKey="Huang, Jinyan" sort="Huang, Jinyan" uniqKey="Huang J" first="Jinyan" last="Huang">Jinyan Huang</name><affiliation><nlm:aff id="A194">Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A195">State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Rui Jin Hospital Affiliated with Shanghai Jiao Tong University School of Medicine, Shanghai, China.</nlm:aff></affiliation></author><author><name sortKey="Karpe, Fredrik" sort="Karpe, Fredrik" uniqKey="Karpe F" first="Fredrik" last="Karpe">Fredrik Karpe</name><affiliation><nlm:aff id="A64">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A196">NIHR Oxford Biomedical Research Centre, OUH Trust, Oxford OX3 7LE, UK.</nlm:aff></affiliation></author><author><name sortKey="Kathiresan, Sekar" sort="Kathiresan, Sekar" uniqKey="Kathiresan S" first="Sekar" last="Kathiresan">Sekar Kathiresan</name><affiliation><nlm:aff id="A6">Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A197">Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.</nlm:aff></affiliation></author><author><name sortKey="Keildson, Sarah" sort="Keildson, Sarah" uniqKey="Keildson S" first="Sarah" last="Keildson">Sarah Keildson</name><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation></author><author><name sortKey="Kiryluk, Krzysztof" sort="Kiryluk, Krzysztof" uniqKey="Kiryluk K" first="Krzysztof" last="Kiryluk">Krzysztof Kiryluk</name><affiliation><nlm:aff id="A191">Department of Medicine, Columbia University College of Physicians and Surgeons, New York 10032, USA.</nlm:aff></affiliation></author><author><name sortKey="Kubo, Michiaki" sort="Kubo, Michiaki" uniqKey="Kubo M" first="Michiaki" last="Kubo">Michiaki Kubo</name><affiliation><nlm:aff id="A198">Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Yokohama 230-0045, Japan.</nlm:aff></affiliation></author><author><name sortKey="Lee, Jong Young" sort="Lee, Jong Young" uniqKey="Lee J" first="Jong-Young" last="Lee">Jong-Young Lee</name><affiliation><nlm:aff id="A199">Center for Genome Science, National Institute of Health, Chungcheongbuk-do, Chungbuk 363–951, Republic of Korea.</nlm:aff></affiliation></author><author><name sortKey="Liang, Liming" sort="Liang, Liming" uniqKey="Liang L" first="Liming" last="Liang">Liming Liang</name><affiliation><nlm:aff id="A194">Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A200">Harvard School of Public Health, Department of Biostatistics, Harvard University, Boston, Massachusetts 2115, USA.</nlm:aff></affiliation></author><author><name sortKey="Lifton, Richard P" sort="Lifton, Richard P" uniqKey="Lifton R" first="Richard P." last="Lifton">Richard P. Lifton</name><affiliation><nlm:aff id="A201">Department of Genetics, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, New Haven, Connecticut 06520, USA.</nlm:aff></affiliation></author><author><name sortKey="Ma, Baoshan" sort="Ma, Baoshan" uniqKey="Ma B" first="Baoshan" last="Ma">Baoshan Ma</name><affiliation><nlm:aff id="A194">Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A202">College of Information Science and Technology, Dalian Maritime University, Dalian, Liaoning 116026, China.</nlm:aff></affiliation></author><author><name sortKey="Mccarroll, Steven A" sort="Mccarroll, Steven A" uniqKey="Mccarroll S" first="Steven A." last="Mccarroll">Steven A. Mccarroll</name><affiliation><nlm:aff id="A6">Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A7">Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A162">Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.</nlm:aff></affiliation></author><author><name sortKey="Mcknight, Amy J" sort="Mcknight, Amy J" uniqKey="Mcknight A" first="Amy J." last="Mcknight">Amy J. Mcknight</name><affiliation><nlm:aff id="A203">Nephrology Research, Centre for Public Health, Queen’s University of Belfast, Belfast, County Down BT9 7AB, UK.</nlm:aff></affiliation></author><author><name sortKey="Min, Josine L" sort="Min, Josine L" uniqKey="Min J" first="Josine L." last="Min">Josine L. Min</name><affiliation><nlm:aff id="A146">School of Social and Community Medicine, University of Bristol, Bristol BS8 2BN, UK.</nlm:aff></affiliation></author><author><name sortKey="Moffatt, Miriam F" sort="Moffatt, Miriam F" uniqKey="Moffatt M" first="Miriam F." last="Moffatt">Miriam F. Moffatt</name><affiliation><nlm:aff id="A173">National Heart and Lung Institute, Imperial College London, London SW3 6LY, UK.</nlm:aff></affiliation></author><author><name sortKey="Montgomery, Grant W" sort="Montgomery, Grant W" uniqKey="Montgomery G" first="Grant W." last="Montgomery">Grant W. Montgomery</name><affiliation><nlm:aff id="A61">QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4006, Australia.</nlm:aff></affiliation></author><author><name sortKey="Murabito, Joanne M" sort="Murabito, Joanne M" uniqKey="Murabito J" first="Joanne M." last="Murabito">Joanne M. Murabito</name><affiliation><nlm:aff id="A127">National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts 01702, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A204">Section of General Internal Medicine, Boston University School of Medicine, Boston, Massachusetts 02118, USA.</nlm:aff></affiliation></author><author><name sortKey="Nicholson, George" sort="Nicholson, George" uniqKey="Nicholson G" first="George" last="Nicholson">George Nicholson</name><affiliation><nlm:aff id="A205">Department of Statistics, University of Oxford, 1 South Parks Road, Oxford OX1 3TG, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A206">MRC Harwell, Harwell Science and Innovation Campus, Harwell OX11 0QG, UK.</nlm:aff></affiliation></author><author><name sortKey="Nyholt, Dale R" sort="Nyholt, Dale R" uniqKey="Nyholt D" first="Dale R." last="Nyholt">Dale R. Nyholt</name><affiliation><nlm:aff id="A61">QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4006, Australia.</nlm:aff></affiliation><affiliation><nlm:aff id="A207">Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland 4059, Australia.</nlm:aff></affiliation></author><author><name sortKey="Okada, Yukinori" sort="Okada, Yukinori" uniqKey="Okada Y" first="Yukinori" last="Okada">Yukinori Okada</name><affiliation><nlm:aff id="A208">Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama 230-0045, Japan.</nlm:aff></affiliation><affiliation><nlm:aff id="A209">Department of Human Genetics and Disease Diversity, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 113-8510 Tokyo, Japan.</nlm:aff></affiliation></author><author><name sortKey="Perry, John R B" sort="Perry, John R B" uniqKey="Perry J" first="John R. B." last="Perry">John R. B. Perry</name><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A24">Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A56">Department of Twin Research and Genetic Epidemiology, King’s College London, London SE1 7EH, UK.</nlm:aff></affiliation></author><author><name sortKey="Dorajoo, Rajkumar" sort="Dorajoo, Rajkumar" uniqKey="Dorajoo R" first="Rajkumar" last="Dorajoo">Rajkumar Dorajoo</name><affiliation><nlm:aff id="A210">Genome Institute of Singapore, Agency for Science, Technology and Research, 138672 Singapore.</nlm:aff></affiliation></author><author><name sortKey="Reinmaa, Eva" sort="Reinmaa, Eva" uniqKey="Reinmaa E" first="Eva" last="Reinmaa">Eva Reinmaa</name><affiliation><nlm:aff id="A14">Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.</nlm:aff></affiliation></author><author><name sortKey="Salem, Rany M" sort="Salem, Rany M" uniqKey="Salem R" first="Rany M." last="Salem">Rany M. Salem</name><affiliation><nlm:aff id="A5">Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children’s Hospital, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A6">Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A7">Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation></author><author><name sortKey="Sandholm, Niina" sort="Sandholm, Niina" uniqKey="Sandholm N" first="Niina" last="Sandholm">Niina Sandholm</name><affiliation><nlm:aff id="A211">Department of Biomedical Engineering and Computational Science, Aalto University School of Science, Helsinki FI-00076, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A212">Department of Medicine, Division of Nephrology, Helsinki University Central Hospital, FI-00290 Helsinki, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A213">Folkhälsan Institute of Genetics, Folkhälsan Research Center, FI-00290 Helsinki, Finland.</nlm:aff></affiliation></author><author><name sortKey="Scott, Robert A" sort="Scott, Robert A" uniqKey="Scott R" first="Robert A." last="Scott">Robert A. Scott</name><affiliation><nlm:aff id="A9">MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:aff></affiliation></author><author><name sortKey="Stolk, Lisette" sort="Stolk, Lisette" uniqKey="Stolk L" first="Lisette" last="Stolk">Lisette Stolk</name><affiliation><nlm:aff id="A34">Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A60">Department of Internal Medicine, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Takahashi, Atsushi" sort="Takahashi, Atsushi" uniqKey="Takahashi A" first="Atsushi" last="Takahashi">Atsushi Takahashi</name><affiliation><nlm:aff id="A208">Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama 230-0045, Japan.</nlm:aff></affiliation></author><author><name sortKey="Tanaka, Toshihiro" sort="Tanaka, Toshihiro" uniqKey="Tanaka T" first="Toshihiro" last="Tanaka">Toshihiro Tanaka</name><affiliation><nlm:aff id="A209">Department of Human Genetics and Disease Diversity, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 113-8510 Tokyo, Japan.</nlm:aff></affiliation><affiliation><nlm:aff id="A214">Laboratory for Cardiovascular Diseases, RIKEN Center for Integrative Medical Sciences, Yokohama 230-0045, Japan.</nlm:aff></affiliation><affiliation><nlm:aff id="A215">Division of Disease Diversity, Bioresource Research Center, Tokyo Medical and Dental University, 113-8510 Tokyo, Japan.</nlm:aff></affiliation></author><author><name sortKey="Van Hooft, Ferdinand M" sort="Van Hooft, Ferdinand M" uniqKey="Van Hooft F" first="Ferdinand M." last="Van Hooft">Ferdinand M. Van Hooft</name><affiliation><nlm:aff id="A70">Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm 17176, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Vinkhuyzen, Anna A E" sort="Vinkhuyzen, Anna A E" uniqKey="Vinkhuyzen A" first="Anna A. E." last="Vinkhuyzen">Anna A. E. Vinkhuyzen</name><affiliation><nlm:aff id="A11">Queensland Brain Institute, The University of Queensland, Brisbane 4072, Australia.</nlm:aff></affiliation></author><author><name sortKey="Westra, Harm Jan" sort="Westra, Harm Jan" uniqKey="Westra H" first="Harm-Jan" last="Westra">Harm-Jan Westra</name><affiliation><nlm:aff id="A29">Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Zheng, Wei" sort="Zheng, Wei" uniqKey="Zheng W" first="Wei" last="Zheng">Wei Zheng</name><affiliation><nlm:aff id="A216">Division of Epidemiology, Department of Medicine; Vanderbilt Epidemiology Center; and Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee 37075, USA.</nlm:aff></affiliation></author><author><name sortKey="Zondervan, Krina T" sort="Zondervan, Krina T" uniqKey="Zondervan K" first="Krina T." last="Zondervan">Krina T. Zondervan</name><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A217">Nuffield Department of Obstetrics & Gynaecology, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation></author><author><name sortKey="Heath, Andrew C" sort="Heath, Andrew C" uniqKey="Heath A" first="Andrew C." last="Heath">Andrew C. Heath</name><affiliation><nlm:aff id="A218">Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:aff></affiliation></author><author><name sortKey="Arveiler, Dominique" sort="Arveiler, Dominique" uniqKey="Arveiler D" first="Dominique" last="Arveiler">Dominique Arveiler</name><affiliation><nlm:aff id="A219">Department of Epidemiology and Public Health, EA3430, University of Strasbourg, Faculty of Medicine, Strasbourg, France.</nlm:aff></affiliation></author><author><name sortKey="Bakker, Stephan J L" sort="Bakker, Stephan J L" uniqKey="Bakker S" first="Stephan J. L." last="Bakker">Stephan J. L. Bakker</name><affiliation><nlm:aff id="A220">Department of Internal Medicine, University Medical Center Groningen, University of Groningen, 9700RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Beilby, John" sort="Beilby, John" uniqKey="Beilby J" first="John" last="Beilby">John Beilby</name><affiliation><nlm:aff id="A87">PathWest Laboratory Medicine of Western Australia, Nedlands, Western Australia 6009, Australia.</nlm:aff></affiliation><affiliation><nlm:aff id="A221">Pathology and Laboratory Medicine, The University of Western Australia, Perth, Western Australia 6009, Australia.</nlm:aff></affiliation></author><author><name sortKey="Bergman, Richard N" sort="Bergman, Richard N" uniqKey="Bergman R" first="Richard N." last="Bergman">Richard N. Bergman</name><affiliation><nlm:aff id="A222">Cedars-Sinai Diabetes and Obesity Research Institute, Los Angeles, California 90048, USA.</nlm:aff></affiliation></author><author><name sortKey="Blangero, John" sort="Blangero, John" uniqKey="Blangero J" first="John" last="Blangero">John Blangero</name><affiliation><nlm:aff id="A92">Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas 78227, USA.</nlm:aff></affiliation></author><author><name sortKey="Bovet, Pascal" sort="Bovet, Pascal" uniqKey="Bovet P" first="Pascal" last="Bovet">Pascal Bovet</name><affiliation><nlm:aff id="A223">Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois and University of Lausanne, 1010 Lausanne, Switzerland.</nlm:aff></affiliation><affiliation><nlm:aff id="A224">Ministry of Health, Victoria, Republic of Seychelles.</nlm:aff></affiliation></author><author><name sortKey="Campbell, Harry" sort="Campbell, Harry" uniqKey="Campbell H" first="Harry" last="Campbell">Harry Campbell</name><affiliation><nlm:aff id="A36">Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK.</nlm:aff></affiliation></author><author><name sortKey="Caulfield, Mark J" sort="Caulfield, Mark J" uniqKey="Caulfield M" first="Mark J." last="Caulfield">Mark J. Caulfield</name><affiliation><nlm:aff id="A181">Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.</nlm:aff></affiliation></author><author><name sortKey="Cesana, Giancarlo" sort="Cesana, Giancarlo" uniqKey="Cesana G" first="Giancarlo" last="Cesana">Giancarlo Cesana</name><affiliation><nlm:aff id="A225">University of Milano, Bicocca, 20126, Italy.</nlm:aff></affiliation></author><author><name sortKey="Chakravarti, Aravinda" sort="Chakravarti, Aravinda" uniqKey="Chakravarti A" first="Aravinda" last="Chakravarti">Aravinda Chakravarti</name><affiliation><nlm:aff id="A44">Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.</nlm:aff></affiliation></author><author><name sortKey="Chasman, Daniel I" sort="Chasman, Daniel I" uniqKey="Chasman D" first="Daniel I." last="Chasman">Daniel I. Chasman</name><affiliation><nlm:aff id="A163">Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, Massachusetts 02215, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A226">Harvard Medical School, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation></author><author><name sortKey="Chines, Peter S" sort="Chines, Peter S" uniqKey="Chines P" first="Peter S." last="Chines">Peter S. Chines</name><affiliation><nlm:aff id="A99">Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA.</nlm:aff></affiliation></author><author><name sortKey="Collins, Francis S" sort="Collins, Francis S" uniqKey="Collins F" first="Francis S." last="Collins">Francis S. Collins</name><affiliation><nlm:aff id="A99">Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA.</nlm:aff></affiliation></author><author><name sortKey="Crawford, Dana C" sort="Crawford, Dana C" uniqKey="Crawford D" first="Dana C." last="Crawford">Dana C. Crawford</name><affiliation><nlm:aff id="A227">Center for Human Genetics Research, Vanderbilt University Medical Center, Nashville, Tennessee 37203, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A228">Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee 37232, USA.</nlm:aff></affiliation></author><author><name sortKey="Cupples, L Adrienne" sort="Cupples, L Adrienne" uniqKey="Cupples L" first="L. Adrienne" last="Cupples">L. Adrienne Cupples</name><affiliation><nlm:aff id="A127">National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts 01702, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A229">Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA.</nlm:aff></affiliation></author><author><name sortKey="Cusi, Daniele" sort="Cusi, Daniele" uniqKey="Cusi D" first="Daniele" last="Cusi">Daniele Cusi</name><affiliation><nlm:aff id="A230">Department of Health Sciences, University of Milano, I 20142, Italy.</nlm:aff></affiliation><affiliation><nlm:aff id="A231">Fondazione Filarete, Milano I 20139, Italy.</nlm:aff></affiliation></author><author><name sortKey="Danesh, John" sort="Danesh, John" uniqKey="Danesh J" first="John" last="Danesh">John Danesh</name><affiliation><nlm:aff id="A232">Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK.</nlm:aff></affiliation></author><author><name sortKey="De Faire, Ulf" sort="De Faire, Ulf" uniqKey="De Faire U" first="Ulf" last="De Faire">Ulf De Faire</name><affiliation><nlm:aff id="A111">Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, Stockholm 17177, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Den Ruijter, Hester M" sort="Den Ruijter, Hester M" uniqKey="Den Ruijter H" first="Hester M." last="Den Ruijter">Hester M. Den Ruijter</name><affiliation><nlm:aff id="A76">Experimental Cardiology Laboratory, Division Heart and Lungs, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A233">Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Dominiczak, Anna F" sort="Dominiczak, Anna F" uniqKey="Dominiczak A" first="Anna F." last="Dominiczak">Anna F. Dominiczak</name><affiliation><nlm:aff id="A234">Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK.</nlm:aff></affiliation></author><author><name sortKey="Erbel, Raimund" sort="Erbel, Raimund" uniqKey="Erbel R" first="Raimund" last="Erbel">Raimund Erbel</name><affiliation><nlm:aff id="A235">Clinic of Cardiology, West-German Heart Centre, University Hospital Essen, 45147 Essen, Germany.</nlm:aff></affiliation></author><author><name sortKey="Erdmann, Jeanette" sort="Erdmann, Jeanette" uniqKey="Erdmann J" first="Jeanette" last="Erdmann">Jeanette Erdmann</name><affiliation><nlm:aff id="A183">German Center for Cardiovascular Research, partner site Hamburg/Lubeck/Kiel, 23562 Lubeck, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A184">Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, D-23562 Lübeck, Germany.</nlm:aff></affiliation></author><author><name sortKey="Eriksson, Johan G" sort="Eriksson, Johan G" uniqKey="Eriksson J" first="Johan G." last="Eriksson">Johan G. Eriksson</name><affiliation><nlm:aff id="A53">National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A236">Department of General Practice and Primary Health Care, University of Helsinki, FI-00290 Helsinki, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A237">Unit of General Practice, Helsinki University Central Hospital, Helsinki 00290, Finland.</nlm:aff></affiliation></author><author><name sortKey="Farrall, Martin" sort="Farrall, Martin" uniqKey="Farrall M" first="Martin" last="Farrall">Martin Farrall</name><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A48">Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, UK.</nlm:aff></affiliation></author><author><name sortKey="Felix, Stephan B" sort="Felix, Stephan B" uniqKey="Felix S" first="Stephan B." last="Felix">Stephan B. Felix</name><affiliation><nlm:aff id="A238">Department of Internal Medicine B, University Medicine Greifswald, D-17475 Greifswald, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A239">DZHK (Deutsches Zentrum für Herz-Kreislaufforschung – German Centre for Cardiovascular Research), partner site Greifswald, D-17475 Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Ferrannini, Ele" sort="Ferrannini, Ele" uniqKey="Ferrannini E" first="Ele" last="Ferrannini">Ele Ferrannini</name><affiliation><nlm:aff id="A240">Department of Internal Medicine, University of Pisa, 56100 Pisa, Italy.</nlm:aff></affiliation><affiliation><nlm:aff id="A241">National Research Council Institute of Clinical Physiology, University of Pisa, 56124 Pisa, Italy.</nlm:aff></affiliation></author><author><name sortKey="Ferrieres, Jean" sort="Ferrieres, Jean" uniqKey="Ferrieres J" first="Jean" last="Ferrières">Jean Ferrières</name><affiliation><nlm:aff id="A242">Department of Cardiology, Toulouse University School of Medicine, Rangueil Hospital, 31400 Toulouse, France.</nlm:aff></affiliation></author><author><name sortKey="Ford, Ian" sort="Ford, Ian" uniqKey="Ford I" first="Ian" last="Ford">Ian Ford</name><affiliation><nlm:aff id="A243">Robertson Center for Biostatistics, University of Glasgow, Glasgow G12 8QQ, UK.</nlm:aff></affiliation></author><author><name sortKey="Forouhi, Nita G" sort="Forouhi, Nita G" uniqKey="Forouhi N" first="Nita G." last="Forouhi">Nita G. Forouhi</name><affiliation><nlm:aff id="A9">MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:aff></affiliation></author><author><name sortKey="Forrester, Terrence" sort="Forrester, Terrence" uniqKey="Forrester T" first="Terrence" last="Forrester">Terrence Forrester</name><affiliation><nlm:aff id="A244">UWI Solutions for Developing Countries, The University of the West Indies, Mona, Kingston 7, Jamaica.</nlm:aff></affiliation></author><author><name sortKey="Franco, Oscar H" sort="Franco, Oscar H" uniqKey="Franco O" first="Oscar H." last="Franco">Oscar H. Franco</name><affiliation><nlm:aff id="A58">Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A59">Department of Epidemiology, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Gansevoort, Ron T" sort="Gansevoort, Ron T" uniqKey="Gansevoort R" first="Ron T." last="Gansevoort">Ron T. Gansevoort</name><affiliation><nlm:aff id="A220">Department of Internal Medicine, University Medical Center Groningen, University of Groningen, 9700RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Gejman, Pablo V" sort="Gejman, Pablo V" uniqKey="Gejman P" first="Pablo V." last="Gejman">Pablo V. Gejman</name><affiliation><nlm:aff id="A245">NorthShore University HealthSystem, Evanston, IL 60201, University of Chicago, Chicago, Illinois, USA.</nlm:aff></affiliation></author><author><name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name><affiliation><nlm:aff id="A85">Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.</nlm:aff></affiliation></author><author><name sortKey="Gottesman, Omri" sort="Gottesman, Omri" uniqKey="Gottesman O" first="Omri" last="Gottesman">Omri Gottesman</name><affiliation><nlm:aff id="A55">The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:aff></affiliation></author><author><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name><affiliation><nlm:aff id="A167">Icelandic Heart Association, Kopavogur 201, Iceland.</nlm:aff></affiliation><affiliation><nlm:aff id="A168">University of Iceland, Reykjavik 101, Iceland.</nlm:aff></affiliation></author><author><name sortKey="Gyllensten, Ulf" sort="Gyllensten, Ulf" uniqKey="Gyllensten U" first="Ulf" last="Gyllensten">Ulf Gyllensten</name><affiliation><nlm:aff id="A136">Uppsala University, Department of Immunology, Genetics, Pathology, SciLifeLab, Rudbeck Laboratory, SE-751 85 Uppsala, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Hall, Alistair S" sort="Hall, Alistair S" uniqKey="Hall A" first="Alistair S." last="Hall">Alistair S. Hall</name><affiliation><nlm:aff id="A246">Leeds MRC Medical Bioinformatics Centre, University of Leeds, Leeds LS2 9LU, UK.</nlm:aff></affiliation></author><author><name sortKey="Harris, Tamara B" sort="Harris, Tamara B" uniqKey="Harris T" first="Tamara B." last="Harris">Tamara B. Harris</name><affiliation><nlm:aff id="A109">Laboratory of Epidemiology and Population Sciences, National Institute on Aging, NIH, Bethesda, Maryland 20892, USA.</nlm:aff></affiliation></author><author><name sortKey="Hattersley, Andrew T" sort="Hattersley, Andrew T" uniqKey="Hattersley A" first="Andrew T." last="Hattersley">Andrew T. Hattersley</name><affiliation><nlm:aff id="A247">Institute of Biomedical & Clinical Science, University of Exeter, Barrack Road, Exeter EX2 5DW, UK.</nlm:aff></affiliation></author><author><name sortKey="Hicks, Andrew A" sort="Hicks, Andrew A" uniqKey="Hicks A" first="Andrew A." last="Hicks">Andrew A. Hicks</name><affiliation><nlm:aff id="A248">Center for Biomedicine, European Academy Bozen, Bolzano (EURAC), Bolzano 39100, Italy (affiliated institute of the University of Lübeck, D-23562 Lübeck, Germany).</nlm:aff></affiliation></author><author><name sortKey="Hindorff, Lucia A" sort="Hindorff, Lucia A" uniqKey="Hindorff L" first="Lucia A." last="Hindorff">Lucia A. Hindorff</name><affiliation><nlm:aff id="A249">Division of Genomic Medicine, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.</nlm:aff></affiliation></author><author><name sortKey="Hingorani, Aroon D" sort="Hingorani, Aroon D" uniqKey="Hingorani A" first="Aroon D." last="Hingorani">Aroon D. Hingorani</name><affiliation><nlm:aff id="A250">Institute of Cardiovascular Science, University College London, London WC1E 6BT, UK.</nlm:aff></affiliation></author><author><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name><affiliation><nlm:aff id="A58">Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A59">Department of Epidemiology, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Homuth, Georg" sort="Homuth, Georg" uniqKey="Homuth G" first="Georg" last="Homuth">Georg Homuth</name><affiliation><nlm:aff id="A73">Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, D-17475 Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Hovingh, G Kees" sort="Hovingh, G Kees" uniqKey="Hovingh G" first="G. Kees" last="Hovingh">G. Kees Hovingh</name><affiliation><nlm:aff id="A251">Department of Vascular Medicine, Academic Medical Center, 1105 AZ Amsterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Humphries, Steve E" sort="Humphries, Steve E" uniqKey="Humphries S" first="Steve E." last="Humphries">Steve E. Humphries</name><affiliation><nlm:aff id="A252">Centre for Cardiovascular Genetics, Institute Cardiovascular Sciences, University College London, London WC1E 6JJ, UK.</nlm:aff></affiliation></author><author><name sortKey="Hunt, Steven C" sort="Hunt, Steven C" uniqKey="Hunt S" first="Steven C." last="Hunt">Steven C. Hunt</name><affiliation><nlm:aff id="A253">Cardiovascular Genetics Division, Department of Internal Medicine, University of Utah, Salt Lake City, Utah 84108, USA.</nlm:aff></affiliation></author><author><name sortKey="Hypponen, Elina" sort="Hypponen, Elina" uniqKey="Hypponen E" first="Elina" last="Hyppönen">Elina Hyppönen</name><affiliation><nlm:aff id="A254">Sansom Institute for Health Research, University of South Australia, Adelaide 5000, South Australia, Australia.</nlm:aff></affiliation><affiliation><nlm:aff id="A255">School of Population Health, University of South Australia, Adelaide 5000, South Australia, Australia.</nlm:aff></affiliation><affiliation><nlm:aff id="A256">South Australian Health and Medical Research Institute, Adelaide, South Australia 5000, Australia.</nlm:aff></affiliation><affiliation><nlm:aff id="A257">Population, Policy, and Practice, University College London Institute of Child Health, London WC1N 1EH, UK.</nlm:aff></affiliation></author><author><name sortKey="Illig, Thomas" sort="Illig, Thomas" uniqKey="Illig T" first="Thomas" last="Illig">Thomas Illig</name><affiliation><nlm:aff id="A119">Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A258">Hannover Unified Biobank, Hannover Medical School, Hannover, D-30625 Hannover, Germany.</nlm:aff></affiliation></author><author><name sortKey="Jacobs, Kevin B" sort="Jacobs, Kevin B" uniqKey="Jacobs K" first="Kevin B." last="Jacobs">Kevin B. Jacobs</name><affiliation><nlm:aff id="A3">Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A79">Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland 21702, USA.</nlm:aff></affiliation></author><author><name sortKey="Jarvelin, Marjo Riitta" sort="Jarvelin, Marjo Riitta" uniqKey="Jarvelin M" first="Marjo-Riitta" last="Jarvelin">Marjo-Riitta Jarvelin</name><affiliation><nlm:aff id="A83">Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A259">National Institute for Health and Welfare, FI-90101 Oulu, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A260">MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College London, London W2 1PG, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A261">Unit of Primary Care, Oulu University Hospital, FI-90220 Oulu, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A263">Institute of Health Sciences, University of Oulu, FI-90014 Oulu, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A263">Institute of Health Sciences, University of Oulu, FI-90014 Oulu, Finland.</nlm:aff></affiliation></author><author><name sortKey="Jockel, Karl Heinz" sort="Jockel, Karl Heinz" uniqKey="Jockel K" first="Karl-Heinz" last="Jöckel">Karl-Heinz Jöckel</name><affiliation><nlm:aff id="A63">Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen, 45147 Essen, Germany.</nlm:aff></affiliation></author><author><name sortKey="Johansen, Berit" sort="Johansen, Berit" uniqKey="Johansen B" first="Berit" last="Johansen">Berit Johansen</name><affiliation><nlm:aff id="A101">Department of Biology, Norwegian University of Science and Technology, 7491 Trondheim, Norway.</nlm:aff></affiliation></author><author><name sortKey="Jousilahti, Pekka" sort="Jousilahti, Pekka" uniqKey="Jousilahti P" first="Pekka" last="Jousilahti">Pekka Jousilahti</name><affiliation><nlm:aff id="A53">National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:aff></affiliation></author><author><name sortKey="Jukema, J Wouter" sort="Jukema, J Wouter" uniqKey="Jukema J" first="J. Wouter" last="Jukema">J. Wouter Jukema</name><affiliation><nlm:aff id="A74">Department of Cardiology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A264">Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands (ICIN), 3501 DG Utrecht, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A265">Interuniversity Cardiology Institute of the Netherlands (ICIN), 3501 DG Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Jula, Antti M" sort="Jula, Antti M" uniqKey="Jula A" first="Antti M." last="Jula">Antti M. Jula</name><affiliation><nlm:aff id="A53">National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:aff></affiliation></author><author><name sortKey="Kaprio, Jaakko" sort="Kaprio, Jaakko" uniqKey="Kaprio J" first="Jaakko" last="Kaprio">Jaakko Kaprio</name><affiliation><nlm:aff id="A53">National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A107">Institute for Molecular Medicine, University of Helsinki, FI-00014 Helsinki, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A137">Hjelt Institute Department of Public Health, University of Helsinki, FI-00014 Helsinki, Finland.</nlm:aff></affiliation></author><author><name sortKey="Kastelein, John J P" sort="Kastelein, John J P" uniqKey="Kastelein J" first="John J. P." last="Kastelein">John J. P. Kastelein</name><affiliation><nlm:aff id="A251">Department of Vascular Medicine, Academic Medical Center, 1105 AZ Amsterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Keinanen Kiukaanniemi, Sirkka M" sort="Keinanen Kiukaanniemi, Sirkka M" uniqKey="Keinanen Kiukaanniemi S" first="Sirkka M." last="Keinanen-Kiukaanniemi">Sirkka M. Keinanen-Kiukaanniemi</name><affiliation><nlm:aff id="A263">Institute of Health Sciences, University of Oulu, FI-90014 Oulu, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A266">Unit of Primary Health Care/General Practice, Oulu University Hospital, FI-90220 Oulu, Finland.</nlm:aff></affiliation></author><author><name sortKey="Kiemeney, Lambertus A" sort="Kiemeney, Lambertus A" uniqKey="Kiemeney L" first="Lambertus A." last="Kiemeney">Lambertus A. Kiemeney</name><affiliation><nlm:aff id="A179">Department for Health Evidence, Radboud University Medical Centre, 6500 HB Nijmegen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A267">Department of Urology, Radboud University Medical Centre, 6500 HB Nijmegen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Knekt, Paul" sort="Knekt, Paul" uniqKey="Knekt P" first="Paul" last="Knekt">Paul Knekt</name><affiliation><nlm:aff id="A53">National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:aff></affiliation></author><author><name sortKey="Kooner, Jaspal S" sort="Kooner, Jaspal S" uniqKey="Kooner J" first="Jaspal S." last="Kooner">Jaspal S. Kooner</name><affiliation><nlm:aff id="A41">Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A173">National Heart and Lung Institute, Imperial College London, London SW3 6LY, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A268">Imperial College Healthcare NHS Trust, London W12 0HS, UK.</nlm:aff></affiliation></author><author><name sortKey="Kooperberg, Charles" sort="Kooperberg, Charles" uniqKey="Kooperberg C" first="Charles" last="Kooperberg">Charles Kooperberg</name><affiliation><nlm:aff id="A49">Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.</nlm:aff></affiliation></author><author><name sortKey="Kovacs, Peter" sort="Kovacs, Peter" uniqKey="Kovacs P" first="Peter" last="Kovacs">Peter Kovacs</name><affiliation><nlm:aff id="A96">Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, D-04103 Leipzig, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A97">Department of Medicine, University of Leipzig, D-04103 Leipzig, Germany.</nlm:aff></affiliation></author><author><name sortKey="Kraja, Aldi T" sort="Kraja, Aldi T" uniqKey="Kraja A" first="Aldi T." last="Kraja">Aldi T. Kraja</name><affiliation><nlm:aff id="A47">Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:aff></affiliation></author><author><name sortKey="Kumari, Meena" sort="Kumari, Meena" uniqKey="Kumari M" first="Meena" last="Kumari">Meena Kumari</name><affiliation><nlm:aff id="A269">Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A270">Department of Biological and Social Epidemiology, University of Essex, Wivenhoe Park, Colchester, Essex CO4 3SQ, UK.</nlm:aff></affiliation></author><author><name sortKey="Kuusisto, Johanna" sort="Kuusisto, Johanna" uniqKey="Kuusisto J" first="Johanna" last="Kuusisto">Johanna Kuusisto</name><affiliation><nlm:aff id="A271">Department of Medicine, Kuopio University Hospital and University of Eastern Finland, FI-70210 Kuopio, Finland.</nlm:aff></affiliation></author><author><name sortKey="Lakka, Timo A" sort="Lakka, Timo A" uniqKey="Lakka T" first="Timo A." last="Lakka">Timo A. Lakka</name><affiliation><nlm:aff id="A125">Kuopio Research Institute of Exercise Medicine, 70100 Kuopio, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A272">Department of Physiology, Institute of Biomedicine, University of Eastern Finland, Kuopio Campus, FI-70211 Kuopio, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A273">Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital and University of Eastern Finland, FI-70210 Kuopio, Finland.</nlm:aff></affiliation></author><author><name sortKey="Langenberg, Claudia" sort="Langenberg, Claudia" uniqKey="Langenberg C" first="Claudia" last="Langenberg">Claudia Langenberg</name><affiliation><nlm:aff id="A9">MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A269">Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK.</nlm:aff></affiliation></author><author><name sortKey="Marchand, Loic Le" sort="Marchand, Loic Le" uniqKey="Marchand L" first="Loic Le" last="Marchand">Loic Le Marchand</name><affiliation><nlm:aff id="A54">Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96813, USA.</nlm:aff></affiliation></author><author><name sortKey="Lehtim Ki, Terho" sort="Lehtim Ki, Terho" uniqKey="Lehtim Ki T" first="Terho" last="Lehtim Ki">Terho Lehtim Ki</name><affiliation><nlm:aff id="A274">Department of Clinical Chemistry, Fimlab Laboratories and School of Medicine University of Tampere, FI-33520 Tampere, Finland.</nlm:aff></affiliation></author><author><name sortKey="Lyssenko, Valeriya" sort="Lyssenko, Valeriya" uniqKey="Lyssenko V" first="Valeriya" last="Lyssenko">Valeriya Lyssenko</name><affiliation><nlm:aff id="A275">Steno Diabetes Center A/S, Gentofte DK-2820, Denmark.</nlm:aff></affiliation><affiliation><nlm:aff id="A276">Lund University Diabetes Centre and Department of Clinical Science, Diabetes & Endocrinology Unit, Lund University, Malmö 221 00, Sweden.</nlm:aff></affiliation></author><author><name sortKey="M Nnisto, Satu" sort="M Nnisto, Satu" uniqKey="M Nnisto S" first="Satu" last="M Nnistö">Satu M Nnistö</name><affiliation><nlm:aff id="A53">National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:aff></affiliation></author><author><name sortKey="Marette, Andre" sort="Marette, Andre" uniqKey="Marette A" first="André" last="Marette">André Marette</name><affiliation><nlm:aff id="A277">Institut Universitaire de Cardiologie et de Pneumologie de Québec, Faculty of Medicine, Laval University, Quebec, QC G1V 0A6, Canada.</nlm:aff></affiliation><affiliation><nlm:aff id="A278">Institute of Nutrition and Functional Foods, Laval University, Quebec, QC G1V 0A6, Canada.</nlm:aff></affiliation></author><author><name sortKey="Matise, Tara C" sort="Matise, Tara C" uniqKey="Matise T" first="Tara C." last="Matise">Tara C. Matise</name><affiliation><nlm:aff id="A39">Department of Genetics, Rutgers University, Piscataway, New Jersey 08854, USA.</nlm:aff></affiliation></author><author><name sortKey="Mckenzie, Colin A" sort="Mckenzie, Colin A" uniqKey="Mckenzie C" first="Colin A." last="Mckenzie">Colin A. Mckenzie</name><affiliation><nlm:aff id="A244">UWI Solutions for Developing Countries, The University of the West Indies, Mona, Kingston 7, Jamaica.</nlm:aff></affiliation></author><author><name sortKey="Mcknight, Barbara" sort="Mcknight, Barbara" uniqKey="Mcknight B" first="Barbara" last="Mcknight">Barbara Mcknight</name><affiliation><nlm:aff id="A279">Department of Biostatistics, University of Washington, Seattle, Washington 98195, USA.</nlm:aff></affiliation></author><author><name sortKey="Moll, Frans L" sort="Moll, Frans L" uniqKey="Moll F" first="Frans L." last="Moll">Frans L. Moll</name><affiliation><nlm:aff id="A280">Department of Surgery, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Morris, Andrew D" sort="Morris, Andrew D" uniqKey="Morris A" first="Andrew D." last="Morris">Andrew D. Morris</name><affiliation><nlm:aff id="A106">Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.</nlm:aff></affiliation></author><author><name sortKey="Morris, Andrew P" sort="Morris, Andrew P" uniqKey="Morris A" first="Andrew P." last="Morris">Andrew P. Morris</name><affiliation><nlm:aff id="A14">Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.</nlm:aff></affiliation><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A281">Department of Biostatistics, University of Liverpool, Liverpool L69 3GA, UK.</nlm:aff></affiliation></author><author><name sortKey="Murray, Jeffrey C" sort="Murray, Jeffrey C" uniqKey="Murray J" first="Jeffrey C." last="Murray">Jeffrey C. Murray</name><affiliation><nlm:aff id="A282">Department of Pediatrics, University of Iowa, Iowa City, Iowa 52242, USA.</nlm:aff></affiliation></author><author><name sortKey="Nelis, Mari" sort="Nelis, Mari" uniqKey="Nelis M" first="Mari" last="Nelis">Mari Nelis</name><affiliation><nlm:aff id="A14">Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.</nlm:aff></affiliation></author><author><name sortKey="Ohlsson, Claes" sort="Ohlsson, Claes" uniqKey="Ohlsson C" first="Claes" last="Ohlsson">Claes Ohlsson</name><affiliation><nlm:aff id="A177">Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg 413 45, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Oldehinkel, Albertine J" sort="Oldehinkel, Albertine J" uniqKey="Oldehinkel A" first="Albertine J." last="Oldehinkel">Albertine J. Oldehinkel</name><affiliation><nlm:aff id="A124">Department of Psychiatry, University of Groningen, University Medical Center Groningen, 9700RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Ong, Ken K" sort="Ong, Ken K" uniqKey="Ong K" first="Ken K." last="Ong">Ken K. Ong</name><affiliation><nlm:aff id="A9">MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A186">MRC Unit for Lifelong Health and Ageing at University College London, London WC1B 5JU, UK.</nlm:aff></affiliation></author><author><name sortKey="Madden, Pamela A F" sort="Madden, Pamela A F" uniqKey="Madden P" first="Pamela A. F." last="Madden">Pamela A. F. Madden</name><affiliation><nlm:aff id="A218">Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:aff></affiliation></author><author><name sortKey="Pasterkamp, Gerard" sort="Pasterkamp, Gerard" uniqKey="Pasterkamp G" first="Gerard" last="Pasterkamp">Gerard Pasterkamp</name><affiliation><nlm:aff id="A76">Experimental Cardiology Laboratory, Division Heart and Lungs, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Peden, John F" sort="Peden, John F" uniqKey="Peden J" first="John F." last="Peden">John F. Peden</name><affiliation><nlm:aff id="A283">Illumina, Inc, Little Chesterford, Cambridge CB10 1XL, UK.</nlm:aff></affiliation></author><author><name sortKey="Peters, Annette" sort="Peters, Annette" uniqKey="Peters A" first="Annette" last="Peters">Annette Peters</name><affiliation><nlm:aff id="A119">Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A130">Deutsches Forschungszentrum für Herz-Kreislauferkrankungen (DZHK) (German Research Centre for Cardiovascular Research), Munich Heart Alliance, D-80636 Munich, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A175">Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany, D-85764 Neuherberg, Germany.</nlm:aff></affiliation></author><author><name sortKey="Postma, Dirkje S" sort="Postma, Dirkje S" uniqKey="Postma D" first="Dirkje S." last="Postma">Dirkje S. Postma</name><affiliation><nlm:aff id="A284">University of Groningen, University Medical Center Groningen, Department of Pulmonary Medicine and Tuberculosis, Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Pramstaller, Peter P" sort="Pramstaller, Peter P" uniqKey="Pramstaller P" first="Peter P." last="Pramstaller">Peter P. Pramstaller</name><affiliation><nlm:aff id="A248">Center for Biomedicine, European Academy Bozen, Bolzano (EURAC), Bolzano 39100, Italy (affiliated institute of the University of Lübeck, D-23562 Lübeck, Germany).</nlm:aff></affiliation><affiliation><nlm:aff id="A285">Department of Neurology, General Central Hospital, Bolzano 39100, Italy.</nlm:aff></affiliation></author><author><name sortKey="Price, Jackie F" sort="Price, Jackie F" uniqKey="Price J" first="Jackie F." last="Price">Jackie F. Price</name><affiliation><nlm:aff id="A36">Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK.</nlm:aff></affiliation></author><author><name sortKey="Qi, Lu" sort="Qi, Lu" uniqKey="Qi L" first="Lu" last="Qi">Lu Qi</name><affiliation><nlm:aff id="A13">Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A25">Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation></author><author><name sortKey="Raitakari, Olli T" sort="Raitakari, Olli T" uniqKey="Raitakari O" first="Olli T." last="Raitakari">Olli T. Raitakari</name><affiliation><nlm:aff id="A286">Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, FI-20521 Turku, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A287">Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, FI-20521 Turku, Finland.</nlm:aff></affiliation></author><author><name sortKey="Rankinen, Tuomo" sort="Rankinen, Tuomo" uniqKey="Rankinen T" first="Tuomo" last="Rankinen">Tuomo Rankinen</name><affiliation><nlm:aff id="A288">Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808, USA.</nlm:aff></affiliation></author><author><name sortKey="Rao, D C" sort="Rao, D C" uniqKey="Rao D" first="D. C." last="Rao">D. C. Rao</name><affiliation><nlm:aff id="A47">Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A71">Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A218">Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:aff></affiliation></author><author><name sortKey="Rice, Treva K" sort="Rice, Treva K" uniqKey="Rice T" first="Treva K." last="Rice">Treva K. Rice</name><affiliation><nlm:aff id="A71">Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A218">Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:aff></affiliation></author><author><name sortKey="Ridker, Paul M" sort="Ridker, Paul M" uniqKey="Ridker P" first="Paul M." last="Ridker">Paul M. Ridker</name><affiliation><nlm:aff id="A163">Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, Massachusetts 02215, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A226">Harvard Medical School, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation></author><author><name sortKey="Rioux, John D" sort="Rioux, John D" uniqKey="Rioux J" first="John D." last="Rioux">John D. Rioux</name><affiliation><nlm:aff id="A143">Montreal Heart Institute, Montreal, Quebec H1T 1C8, Canada.</nlm:aff></affiliation><affiliation><nlm:aff id="A289">Université de Montréal, Montreal, Quebec H1T 1C8, Canada.</nlm:aff></affiliation></author><author><name sortKey="Ritchie, Marylyn D" sort="Ritchie, Marylyn D" uniqKey="Ritchie M" first="Marylyn D." last="Ritchie">Marylyn D. Ritchie</name><affiliation><nlm:aff id="A290">Center for Systems Genomics, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.</nlm:aff></affiliation></author><author><name sortKey="Rudan, Igor" sort="Rudan, Igor" uniqKey="Rudan I" first="Igor" last="Rudan">Igor Rudan</name><affiliation><nlm:aff id="A36">Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A291">Croatian Centre for Global Health, Faculty of Medicine, University of Split, 21000 Split, Croatia.</nlm:aff></affiliation></author><author><name sortKey="Salomaa, Veikko" sort="Salomaa, Veikko" uniqKey="Salomaa V" first="Veikko" last="Salomaa">Veikko Salomaa</name><affiliation><nlm:aff id="A53">National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:aff></affiliation></author><author><name sortKey="Samani, Nilesh J" sort="Samani, Nilesh J" uniqKey="Samani N" first="Nilesh J." last="Samani">Nilesh J. Samani</name><affiliation><nlm:aff id="A114">Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester LE3 9QP, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A115">National Institute for Health Research (NIHR) Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester LE3 9QP, UK.</nlm:aff></affiliation></author><author><name sortKey="Saramies, Jouko" sort="Saramies, Jouko" uniqKey="Saramies J" first="Jouko" last="Saramies">Jouko Saramies</name><affiliation><nlm:aff id="A292">South Carelia Central Hospital, 53130 Lappeenranta, Finland.</nlm:aff></affiliation></author><author><name sortKey="Sarzynski, Mark A" sort="Sarzynski, Mark A" uniqKey="Sarzynski M" first="Mark A." last="Sarzynski">Mark A. Sarzynski</name><affiliation><nlm:aff id="A288">Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808, USA.</nlm:aff></affiliation></author><author><name sortKey="Schunkert, Heribert" sort="Schunkert, Heribert" uniqKey="Schunkert H" first="Heribert" last="Schunkert">Heribert Schunkert</name><affiliation><nlm:aff id="A130">Deutsches Forschungszentrum für Herz-Kreislauferkrankungen (DZHK) (German Research Centre for Cardiovascular Research), Munich Heart Alliance, D-80636 Munich, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A131">Deutsches Herzzentrum München, Technische Universität München, D-80636 Munich, Germany.</nlm:aff></affiliation></author><author><name sortKey="Schwarz, Peter E H" sort="Schwarz, Peter E H" uniqKey="Schwarz P" first="Peter E. H." last="Schwarz">Peter E. H. Schwarz</name><affiliation><nlm:aff id="A121">Department of Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, D-01307 Dresden, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A293">Paul Langerhans Institute Dresden, German Center for Diabetes Research (DZD), 01307 Dresden, Germany.</nlm:aff></affiliation></author><author><name sortKey="Sever, Peter" sort="Sever, Peter" uniqKey="Sever P" first="Peter" last="Sever">Peter Sever</name><affiliation><nlm:aff id="A294">International Centre for Circulatory Health, Imperial College London, London W2 1PG, UK.</nlm:aff></affiliation></author><author><name sortKey="Shuldiner, Alan R" sort="Shuldiner, Alan R" uniqKey="Shuldiner A" first="Alan R." last="Shuldiner">Alan R. Shuldiner</name><affiliation><nlm:aff id="A295">Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A296">Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A297">Geriatric Research and Education Clinical Center, Vetrans Administration Medical Center, Baltimore, Maryland 21201, USA.</nlm:aff></affiliation></author><author><name sortKey="Sinisalo, Juha" sort="Sinisalo, Juha" uniqKey="Sinisalo J" first="Juha" last="Sinisalo">Juha Sinisalo</name><affiliation><nlm:aff id="A298">Helsinki University Central Hospital Heart and Lung Center, Department of Medicine, Helsinki University Central Hospital, FI-00290 Helsinki, Finland.</nlm:aff></affiliation></author><author><name sortKey="Stolk, Ronald P" sort="Stolk, Ronald P" uniqKey="Stolk R" first="Ronald P." last="Stolk">Ronald P. Stolk</name><affiliation><nlm:aff id="A169">Department of Epidemiology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Strauch, Konstantin" sort="Strauch, Konstantin" uniqKey="Strauch K" first="Konstantin" last="Strauch">Konstantin Strauch</name><affiliation><nlm:aff id="A85">Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A153">Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, D-81377 Munich, Germany.</nlm:aff></affiliation></author><author><name sortKey="Tonjes, Anke" sort="Tonjes, Anke" uniqKey="Tonjes A" first="Anke" last="Tönjes">Anke Tönjes</name><affiliation><nlm:aff id="A96">Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, D-04103 Leipzig, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A97">Department of Medicine, University of Leipzig, D-04103 Leipzig, Germany.</nlm:aff></affiliation></author><author><name sortKey="Tregouet, David Alexandre" sort="Tregouet, David Alexandre" uniqKey="Tregouet D" first="David-Alexandre" last="Trégouët">David-Alexandre Trégouët</name><affiliation><nlm:aff id="A299">Sorbonne Universités, UPMC Univ Paris 06, UMR S 1166, F-75013 Paris, France.</nlm:aff></affiliation><affiliation><nlm:aff id="A300">INSERM, UMR S 1166, Team Genomics and Physiopathology of Cardiovascular Diseases, F-75013 Paris, France.</nlm:aff></affiliation><affiliation><nlm:aff id="A301">Institute for Cardiometabolism And Nutrition (ICAN), F-75013 Paris, France.</nlm:aff></affiliation></author><author><name sortKey="Tremblay, Angelo" sort="Tremblay, Angelo" uniqKey="Tremblay A" first="Angelo" last="Tremblay">Angelo Tremblay</name><affiliation><nlm:aff id="A302">Department of Kinesiology, Laval University, Quebec QC G1V 0A6, Canada.</nlm:aff></affiliation></author><author><name sortKey="Tremoli, Elena" sort="Tremoli, Elena" uniqKey="Tremoli E" first="Elena" last="Tremoli">Elena Tremoli</name><affiliation><nlm:aff id="A303">Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano & Centro Cardiologico Monzino, Instituto di Ricovero e Cura a Carattere Scientifico, Milan 20133, Italy.</nlm:aff></affiliation></author><author><name sortKey="Virtamo, Jarmo" sort="Virtamo, Jarmo" uniqKey="Virtamo J" first="Jarmo" last="Virtamo">Jarmo Virtamo</name><affiliation><nlm:aff id="A53">National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:aff></affiliation></author><author><name sortKey="Vohl, Marie Claude" sort="Vohl, Marie Claude" uniqKey="Vohl M" first="Marie-Claude" last="Vohl">Marie-Claude Vohl</name><affiliation><nlm:aff id="A278">Institute of Nutrition and Functional Foods, Laval University, Quebec, QC G1V 0A6, Canada.</nlm:aff></affiliation><affiliation><nlm:aff id="A304">Department of Food Science and Nutrition, Laval University, Quebec QC G1V 0A6, Canada.</nlm:aff></affiliation></author><author><name sortKey="Volker, Uwe" sort="Volker, Uwe" uniqKey="Volker U" first="Uwe" last="Völker">Uwe Völker</name><affiliation><nlm:aff id="A73">Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, D-17475 Greifswald, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A239">DZHK (Deutsches Zentrum für Herz-Kreislaufforschung – German Centre for Cardiovascular Research), partner site Greifswald, D-17475 Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Waeber, Gerard" sort="Waeber, Gerard" uniqKey="Waeber G" first="Gérard" last="Waeber">Gérard Waeber</name><affiliation><nlm:aff id="A305">Department of Internal Medicine, University Hospital (CHUV) and University of Lausanne, Lausanne 1011, Switzerland.</nlm:aff></affiliation></author><author><name sortKey="Willemsen, Gonneke" sort="Willemsen, Gonneke" uniqKey="Willemsen G" first="Gonneke" last="Willemsen">Gonneke Willemsen</name><affiliation><nlm:aff id="A133">Biological Psychology, VU University Amsterdam, 1081BT Amsterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Witteman, Jacqueline C" sort="Witteman, Jacqueline C" uniqKey="Witteman J" first="Jacqueline C." last="Witteman">Jacqueline C. Witteman</name><affiliation><nlm:aff id="A59">Department of Epidemiology, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Zillikens, M Carola" sort="Zillikens, M Carola" uniqKey="Zillikens M" first="M. Carola" last="Zillikens">M. Carola Zillikens</name><affiliation><nlm:aff id="A58">Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A60">Department of Internal Medicine, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Adair, Linda S" sort="Adair, Linda S" uniqKey="Adair L" first="Linda S." last="Adair">Linda S. Adair</name><affiliation><nlm:aff id="A306">Department of Nutrition, University of North Carolina, Chapel Hill, North Carolina 27599, USA.</nlm:aff></affiliation></author><author><name sortKey="Amouyel, Philippe" sort="Amouyel, Philippe" uniqKey="Amouyel P" first="Philippe" last="Amouyel">Philippe Amouyel</name><affiliation><nlm:aff id="A307">Institut Pasteur de Lille; INSERM, U744; Université de Lille 2; F-59000 Lille, France.</nlm:aff></affiliation></author><author><name sortKey="Asselbergs, Folkert W" sort="Asselbergs, Folkert W" uniqKey="Asselbergs F" first="Folkert W." last="Asselbergs">Folkert W. Asselbergs</name><affiliation><nlm:aff id="A250">Institute of Cardiovascular Science, University College London, London WC1E 6BT, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A264">Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands (ICIN), 3501 DG Utrecht, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A308">Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Assimes, Themistocles L" sort="Assimes, Themistocles L" uniqKey="Assimes T" first="Themistocles L." last="Assimes">Themistocles L. Assimes</name><affiliation><nlm:aff id="A309">Department of Medicine, Stanford University School of Medicine, Palo Alto, California 94304, USA.</nlm:aff></affiliation></author><author><name sortKey="Bochud, Murielle" sort="Bochud, Murielle" uniqKey="Bochud M" first="Murielle" last="Bochud">Murielle Bochud</name><affiliation><nlm:aff id="A223">Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois and University of Lausanne, 1010 Lausanne, Switzerland.</nlm:aff></affiliation><affiliation><nlm:aff id="A224">Ministry of Health, Victoria, Republic of Seychelles.</nlm:aff></affiliation></author><author><name sortKey="Boehm, Bernhard O" sort="Boehm, Bernhard O" uniqKey="Boehm B" first="Bernhard O." last="Boehm">Bernhard O. Boehm</name><affiliation><nlm:aff id="A310">Lee Kong Chian School of Medicine, Imperial College London and Nanyang Technological University, Singapore, 637553 Singapore, Singapore.</nlm:aff></affiliation><affiliation><nlm:aff id="A311">Department of Internal Medicine I, Ulm University Medical Centre, D-89081 Ulm, Germany.</nlm:aff></affiliation></author><author><name sortKey="Boerwinkle, Eric" sort="Boerwinkle, Eric" uniqKey="Boerwinkle E" first="Eric" last="Boerwinkle">Eric Boerwinkle</name><affiliation><nlm:aff id="A312">Health Science Center at Houston, University of Texas, Houston, Texas 77030, USA.</nlm:aff></affiliation></author><author><name sortKey="Bornstein, Stefan R" sort="Bornstein, Stefan R" uniqKey="Bornstein S" first="Stefan R." last="Bornstein">Stefan R. Bornstein</name><affiliation><nlm:aff id="A121">Department of Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, D-01307 Dresden, Germany.</nlm:aff></affiliation></author><author><name sortKey="Bottinger, Erwin P" sort="Bottinger, Erwin P" uniqKey="Bottinger E" first="Erwin P." last="Bottinger">Erwin P. Bottinger</name><affiliation><nlm:aff id="A55">The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:aff></affiliation></author><author><name sortKey="Bouchard, Claude" sort="Bouchard, Claude" uniqKey="Bouchard C" first="Claude" last="Bouchard">Claude Bouchard</name><affiliation><nlm:aff id="A288">Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808, USA.</nlm:aff></affiliation></author><author><name sortKey="Cauchi, Stephane" sort="Cauchi, Stephane" uniqKey="Cauchi S" first="Stéphane" last="Cauchi">Stéphane Cauchi</name><affiliation><nlm:aff id="A80">CNRS UMR 8199, F-59019 Lille, France.</nlm:aff></affiliation><affiliation><nlm:aff id="A81">European Genomic Institute for Diabetes, F-59000 Lille, France.</nlm:aff></affiliation><affiliation><nlm:aff id="A82">Université de Lille 2, F-59000 Lille, France.</nlm:aff></affiliation></author><author><name sortKey="Chambers, John C" sort="Chambers, John C" uniqKey="Chambers J" first="John C." last="Chambers">John C. Chambers</name><affiliation><nlm:aff id="A41">Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A83">Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A268">Imperial College Healthcare NHS Trust, London W12 0HS, UK.</nlm:aff></affiliation></author><author><name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J." last="Chanock">Stephen J. Chanock</name><affiliation><nlm:aff id="A3">Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.</nlm:aff></affiliation></author><author><name sortKey="Cooper, Richard S" sort="Cooper, Richard S" uniqKey="Cooper R" first="Richard S." last="Cooper">Richard S. Cooper</name><affiliation><nlm:aff id="A174">Department of Public Health Sciences, Stritch School of Medicine, Loyola University of Chicago, Maywood, Illinois 61053, USA.</nlm:aff></affiliation></author><author><name sortKey="De Bakker, Paul I W" sort="De Bakker, Paul I W" uniqKey="De Bakker P" first="Paul I. W." last="De Bakker">Paul I. W. De Bakker</name><affiliation><nlm:aff id="A77">Department of Medical Genetics, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A313">Department of Medicine, Division of Genetics, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A314">Department of Epidemiology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Dedoussis, George" sort="Dedoussis, George" uniqKey="Dedoussis G" first="George" last="Dedoussis">George Dedoussis</name><affiliation><nlm:aff id="A105">Department of Dietetics-Nutrition, Harokopio University, 17671 Athens, Greece.</nlm:aff></affiliation></author><author><name sortKey="Ferrucci, Luigi" sort="Ferrucci, Luigi" uniqKey="Ferrucci L" first="Luigi" last="Ferrucci">Luigi Ferrucci</name><affiliation><nlm:aff id="A72">Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland 21225, USA.</nlm:aff></affiliation></author><author><name sortKey="Franks, Paul W" sort="Franks, Paul W" uniqKey="Franks P" first="Paul W." last="Franks">Paul W. Franks</name><affiliation><nlm:aff id="A25">Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A66">Department of Clinical Sciences, Genetic & Molecular Epidemiology Unit, Lund University Diabetes Center, Skåne University Hosptial, Malmö 205 02, Sweden.</nlm:aff></affiliation><affiliation><nlm:aff id="A67">Department of Public Health and Clinical Medicine, Unit of Medicine, Umeå University, Umeå 901 87, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Froguel, Philippe" sort="Froguel, Philippe" uniqKey="Froguel P" first="Philippe" last="Froguel">Philippe Froguel</name><affiliation><nlm:aff id="A65">Department of Genomics of Common Disease, School of Public Health, Imperial College London, Hammersmith Hospital, London W12 0NN, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A80">CNRS UMR 8199, F-59019 Lille, France.</nlm:aff></affiliation><affiliation><nlm:aff id="A81">European Genomic Institute for Diabetes, F-59000 Lille, France.</nlm:aff></affiliation><affiliation><nlm:aff id="A82">Université de Lille 2, F-59000 Lille, France.</nlm:aff></affiliation></author><author><name sortKey="Groop, Leif C" sort="Groop, Leif C" uniqKey="Groop L" first="Leif C." last="Groop">Leif C. Groop</name><affiliation><nlm:aff id="A107">Institute for Molecular Medicine, University of Helsinki, FI-00014 Helsinki, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A276">Lund University Diabetes Centre and Department of Clinical Science, Diabetes & Endocrinology Unit, Lund University, Malmö 221 00, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Haiman, Christopher A" sort="Haiman, Christopher A" uniqKey="Haiman C" first="Christopher A." last="Haiman">Christopher A. Haiman</name><affiliation><nlm:aff id="A165">Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA.</nlm:aff></affiliation></author><author><name sortKey="Hamsten, Anders" sort="Hamsten, Anders" uniqKey="Hamsten A" first="Anders" last="Hamsten">Anders Hamsten</name><affiliation><nlm:aff id="A70">Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm 17176, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Hui, Jennie" sort="Hui, Jennie" uniqKey="Hui J" first="Jennie" last="Hui">Jennie Hui</name><affiliation><nlm:aff id="A87">PathWest Laboratory Medicine of Western Australia, Nedlands, Western Australia 6009, Australia.</nlm:aff></affiliation><affiliation><nlm:aff id="A221">Pathology and Laboratory Medicine, The University of Western Australia, Perth, Western Australia 6009, Australia.</nlm:aff></affiliation><affiliation><nlm:aff id="A315">School of Population Health, The University of Western Australia, Nedlands, Western Australia 6009, Australia.</nlm:aff></affiliation></author><author><name sortKey="Hunter, David J" sort="Hunter, David J" uniqKey="Hunter D" first="David J." last="Hunter">David J. Hunter</name><affiliation><nlm:aff id="A13">Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A25">Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A194">Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation></author><author><name sortKey="Hveem, Kristian" sort="Hveem, Kristian" uniqKey="Hveem K" first="Kristian" last="Hveem">Kristian Hveem</name><affiliation><nlm:aff id="A132">Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim 7489, Norway.</nlm:aff></affiliation></author><author><name sortKey="Kaplan, Robert C" sort="Kaplan, Robert C" uniqKey="Kaplan R" first="Robert C." last="Kaplan">Robert C. Kaplan</name><affiliation><nlm:aff id="A316">Albert Einstein College of Medicine, Department of Epidemiology and Population Health, Belfer 1306, New York 10461, USA.</nlm:aff></affiliation></author><author><name sortKey="Kivimaki, Mika" sort="Kivimaki, Mika" uniqKey="Kivimaki M" first="Mika" last="Kivimaki">Mika Kivimaki</name><affiliation><nlm:aff id="A269">Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK.</nlm:aff></affiliation></author><author><name sortKey="Kuh, Diana" sort="Kuh, Diana" uniqKey="Kuh D" first="Diana" last="Kuh">Diana Kuh</name><affiliation><nlm:aff id="A186">MRC Unit for Lifelong Health and Ageing at University College London, London WC1B 5JU, UK.</nlm:aff></affiliation></author><author><name sortKey="Laakso, Markku" sort="Laakso, Markku" uniqKey="Laakso M" first="Markku" last="Laakso">Markku Laakso</name><affiliation><nlm:aff id="A271">Department of Medicine, Kuopio University Hospital and University of Eastern Finland, FI-70210 Kuopio, Finland.</nlm:aff></affiliation></author><author><name sortKey="Liu, Yongmei" sort="Liu, Yongmei" uniqKey="Liu Y" first="Yongmei" last="Liu">Yongmei Liu</name><affiliation><nlm:aff id="A317">Center for Human Genetics, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, USA.</nlm:aff></affiliation></author><author><name sortKey="Martin, Nicholas G" sort="Martin, Nicholas G" uniqKey="Martin N" first="Nicholas G." last="Martin">Nicholas G. Martin</name><affiliation><nlm:aff id="A61">QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4006, Australia.</nlm:aff></affiliation></author><author><name sortKey="M Rz, Winfried" sort="M Rz, Winfried" uniqKey="M Rz W" first="Winfried" last="M Rz">Winfried M Rz</name><affiliation><nlm:aff id="A51">Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, D-68187 Mannheim, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A164">Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz 8036, Austria.</nlm:aff></affiliation><affiliation><nlm:aff id="A318">Synlab Academy, Synlab Services GmbH, 68163 Mannheim, Germany.</nlm:aff></affiliation></author><author><name sortKey="Melbye, Mads" sort="Melbye, Mads" uniqKey="Melbye M" first="Mads" last="Melbye">Mads Melbye</name><affiliation><nlm:aff id="A309">Department of Medicine, Stanford University School of Medicine, Palo Alto, California 94304, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A319">Department of Clinical Medicine, Copenhagen University, 2200 Copenhagen, Denmark.</nlm:aff></affiliation></author><author><name sortKey="Metspalu, Andres" sort="Metspalu, Andres" uniqKey="Metspalu A" first="Andres" last="Metspalu">Andres Metspalu</name><affiliation><nlm:aff id="A14">Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.</nlm:aff></affiliation><affiliation><nlm:aff id="A147">Institute of Molecular and Cell Biology, University of Tartu, Tartu 51010, Estonia.</nlm:aff></affiliation></author><author><name sortKey="Moebus, Susanne" sort="Moebus, Susanne" uniqKey="Moebus S" first="Susanne" last="Moebus">Susanne Moebus</name><affiliation><nlm:aff id="A63">Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen, 45147 Essen, Germany.</nlm:aff></affiliation></author><author><name sortKey="Munroe, Patricia B" sort="Munroe, Patricia B" uniqKey="Munroe P" first="Patricia B." last="Munroe">Patricia B. Munroe</name><affiliation><nlm:aff id="A181">Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.</nlm:aff></affiliation></author><author><name sortKey="Nj Lstad, Inger" sort="Nj Lstad, Inger" uniqKey="Nj Lstad I" first="Inger" last="Nj Lstad">Inger Nj Lstad</name><affiliation><nlm:aff id="A185">Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, 9037 Tromsø, Norway.</nlm:aff></affiliation></author><author><name sortKey="Oostra, Ben A" sort="Oostra, Ben A" uniqKey="Oostra B" first="Ben A." last="Oostra">Ben A. Oostra</name><affiliation><nlm:aff id="A32">Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC University Medical Center, 3015 GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A84">Center for Medical Sytems Biology, 2300 RC Leiden, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A320">Department of Clinical Genetics, Erasmus MC University Medical Center, 3000 CA Rotterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Palmer, Colin N A" sort="Palmer, Colin N A" uniqKey="Palmer C" first="Colin N. A." last="Palmer">Colin N. A. Palmer</name><affiliation><nlm:aff id="A106">Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.</nlm:aff></affiliation></author><author><name sortKey="Pedersen, Nancy L" sort="Pedersen, Nancy L" uniqKey="Pedersen N" first="Nancy L." last="Pedersen">Nancy L. Pedersen</name><affiliation><nlm:aff id="A15">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Perola, Markus" sort="Perola, Markus" uniqKey="Perola M" first="Markus" last="Perola">Markus Perola</name><affiliation><nlm:aff id="A14">Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.</nlm:aff></affiliation><affiliation><nlm:aff id="A53">National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A107">Institute for Molecular Medicine, University of Helsinki, FI-00014 Helsinki, Finland.</nlm:aff></affiliation></author><author><name sortKey="Perusse, Louis" sort="Perusse, Louis" uniqKey="Perusse L" first="Louis" last="Pérusse">Louis Pérusse</name><affiliation><nlm:aff id="A278">Institute of Nutrition and Functional Foods, Laval University, Quebec, QC G1V 0A6, Canada.</nlm:aff></affiliation><affiliation><nlm:aff id="A302">Department of Kinesiology, Laval University, Quebec QC G1V 0A6, Canada.</nlm:aff></affiliation></author><author><name sortKey="Peters, Ulrike" sort="Peters, Ulrike" uniqKey="Peters U" first="Ulrike" last="Peters">Ulrike Peters</name><affiliation><nlm:aff id="A49">Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.</nlm:aff></affiliation></author><author><name sortKey="Power, Chris" sort="Power, Chris" uniqKey="Power C" first="Chris" last="Power">Chris Power</name><affiliation><nlm:aff id="A257">Population, Policy, and Practice, University College London Institute of Child Health, London WC1N 1EH, UK.</nlm:aff></affiliation></author><author><name sortKey="Quertermous, Thomas" sort="Quertermous, Thomas" uniqKey="Quertermous T" first="Thomas" last="Quertermous">Thomas Quertermous</name><affiliation><nlm:aff id="A309">Department of Medicine, Stanford University School of Medicine, Palo Alto, California 94304, USA.</nlm:aff></affiliation></author><author><name sortKey="Rauramaa, Rainer" sort="Rauramaa, Rainer" uniqKey="Rauramaa R" first="Rainer" last="Rauramaa">Rainer Rauramaa</name><affiliation><nlm:aff id="A125">Kuopio Research Institute of Exercise Medicine, 70100 Kuopio, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A273">Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital and University of Eastern Finland, FI-70210 Kuopio, Finland.</nlm:aff></affiliation></author><author><name sortKey="Rivadeneira, Fernando" sort="Rivadeneira, Fernando" uniqKey="Rivadeneira F" first="Fernando" last="Rivadeneira">Fernando Rivadeneira</name><affiliation><nlm:aff id="A58">Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A59">Department of Epidemiology, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A60">Department of Internal Medicine, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Saaristo, Timo E" sort="Saaristo, Timo E" uniqKey="Saaristo T" first="Timo E." last="Saaristo">Timo E. Saaristo</name><affiliation><nlm:aff id="A321">Finnish Diabetes Association, Kirjoniementie 15, FI-33680 Tampere, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A322">Pirkanmaa Hospital District, FI-33521 Tampere, Finland.</nlm:aff></affiliation></author><author><name sortKey="Saleheen, Danish" sort="Saleheen, Danish" uniqKey="Saleheen D" first="Danish" last="Saleheen">Danish Saleheen</name><affiliation><nlm:aff id="A232">Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A323">Center for Non-Communicable Diseases, Karatchi, Pakistan.</nlm:aff></affiliation><affiliation><nlm:aff id="A324">Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.</nlm:aff></affiliation></author><author><name sortKey="Sattar, Naveed" sort="Sattar, Naveed" uniqKey="Sattar N" first="Naveed" last="Sattar">Naveed Sattar</name><affiliation><nlm:aff id="A325">BHF Glasgow Cardiovascular Research Centre, Division of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G12 8TA, UK.</nlm:aff></affiliation></author><author><name sortKey="Schadt, Eric E" sort="Schadt, Eric E" uniqKey="Schadt E" first="Eric E." last="Schadt">Eric E. Schadt</name><affiliation><nlm:aff id="A326">Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10580, USA.</nlm:aff></affiliation></author><author><name sortKey="Schlessinger, David" sort="Schlessinger, David" uniqKey="Schlessinger D" first="David" last="Schlessinger">David Schlessinger</name><affiliation><nlm:aff id="A155">Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland 21224, USA.</nlm:aff></affiliation></author><author><name sortKey="Slagboom, P Eline" sort="Slagboom, P Eline" uniqKey="Slagboom P" first="P. Eline" last="Slagboom">P. Eline Slagboom</name><affiliation><nlm:aff id="A34">Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A35">Department of Molecular Epidemiology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Snieder, Harold" sort="Snieder, Harold" uniqKey="Snieder H" first="Harold" last="Snieder">Harold Snieder</name><affiliation><nlm:aff id="A169">Department of Epidemiology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Spector, Tim D" sort="Spector, Tim D" uniqKey="Spector T" first="Tim D." last="Spector">Tim D. Spector</name><affiliation><nlm:aff id="A56">Department of Twin Research and Genetic Epidemiology, King’s College London, London SE1 7EH, UK.</nlm:aff></affiliation></author><author><name sortKey="Thorsteinsdottir, Unnur" sort="Thorsteinsdottir, Unnur" uniqKey="Thorsteinsdottir U" first="Unnur" last="Thorsteinsdottir">Unnur Thorsteinsdottir</name><affiliation><nlm:aff id="A171">deCODE Genetics, Amgen Inc., Reykjavik 101, Iceland.</nlm:aff></affiliation><affiliation><nlm:aff id="A327">Faculty of Medicine, University of Iceland, Reykjavik 101, Iceland.</nlm:aff></affiliation></author><author><name sortKey="Stumvoll, Michael" sort="Stumvoll, Michael" uniqKey="Stumvoll M" first="Michael" last="Stumvoll">Michael Stumvoll</name><affiliation><nlm:aff id="A96">Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, D-04103 Leipzig, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A97">Department of Medicine, University of Leipzig, D-04103 Leipzig, Germany.</nlm:aff></affiliation></author><author><name sortKey="Tuomilehto, Jaakko" sort="Tuomilehto, Jaakko" uniqKey="Tuomilehto J" first="Jaakko" last="Tuomilehto">Jaakko Tuomilehto</name><affiliation><nlm:aff id="A53">National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A328">Institute for Health Research, University Hospital of La Paz (IdiPaz), 28046 Madrid, Spain.</nlm:aff></affiliation><affiliation><nlm:aff id="A329">Diabetes Research Group, King Abdulaziz University, 21589 Jeddah, Saudi Arabia.</nlm:aff></affiliation><affiliation><nlm:aff id="A330">Centre for Vascular Prevention, Danube-University Krems, 3500 Krems, Austria.</nlm:aff></affiliation></author><author><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="André G." last="Uitterlinden">André G. Uitterlinden</name><affiliation><nlm:aff id="A58">Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A59">Department of Epidemiology, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A60">Department of Internal Medicine, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Uusitupa, Matti" sort="Uusitupa, Matti" uniqKey="Uusitupa M" first="Matti" last="Uusitupa">Matti Uusitupa</name><affiliation><nlm:aff id="A331">Department of Public Health and Clinical Nutrition, University of Eastern Finland, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A332">Research Unit, Kuopio University Hospital, FI-70210 Kuopio, Finland.</nlm:aff></affiliation></author><author><name sortKey="Van Der Harst, Pim" sort="Van Der Harst, Pim" uniqKey="Van Der Harst P" first="Pim" last="Van Der Harst">Pim Van Der Harst</name><affiliation><nlm:aff id="A29">Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A57">Department of Cardiology, University Medical Center Groningen, University of Groningen, 9700RB Groningen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A264">Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands (ICIN), 3501 DG Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Walker, Mark" sort="Walker, Mark" uniqKey="Walker M" first="Mark" last="Walker">Mark Walker</name><affiliation><nlm:aff id="A333">Institute of Cellular Medicine, Newcastle University, Newcastle NE1 7RU, UK.</nlm:aff></affiliation></author><author><name sortKey="Wallaschofski, Henri" sort="Wallaschofski, Henri" uniqKey="Wallaschofski H" first="Henri" last="Wallaschofski">Henri Wallaschofski</name><affiliation><nlm:aff id="A239">DZHK (Deutsches Zentrum für Herz-Kreislaufforschung – German Centre for Cardiovascular Research), partner site Greifswald, D-17475 Greifswald, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A334">Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, D-17475 Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Wareham, Nicholas J" sort="Wareham, Nicholas J" uniqKey="Wareham N" first="Nicholas J." last="Wareham">Nicholas J. Wareham</name><affiliation><nlm:aff id="A9">MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:aff></affiliation></author><author><name sortKey="Watkins, Hugh" sort="Watkins, Hugh" uniqKey="Watkins H" first="Hugh" last="Watkins">Hugh Watkins</name><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A48">Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, UK.</nlm:aff></affiliation></author><author><name sortKey="Weir, David R" sort="Weir, David R" uniqKey="Weir D" first="David R." last="Weir">David R. Weir</name><affiliation><nlm:aff id="A26">Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan 48104, USA.</nlm:aff></affiliation></author><author><name sortKey="Wichmann, H Erich" sort="Wichmann, H Erich" uniqKey="Wichmann H" first="H-Erich" last="Wichmann">H-Erich Wichmann</name><affiliation><nlm:aff id="A335">Institute of Medical Informatics, Biometry and Epidemiology, Chair of Epidemiology, Ludwig-Maximilians-Universität, D-85764 Munich, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A336">Klinikum Grosshadern, D-81377 Munich, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A337">Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany, D-85764 Neuherberg, Germany.</nlm:aff></affiliation></author><author><name sortKey="Wilson, James F" sort="Wilson, James F" uniqKey="Wilson J" first="James F." last="Wilson">James F. Wilson</name><affiliation><nlm:aff id="A36">Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK.</nlm:aff></affiliation></author><author><name sortKey="Zanen, Pieter" sort="Zanen, Pieter" uniqKey="Zanen P" first="Pieter" last="Zanen">Pieter Zanen</name><affiliation><nlm:aff id="A338">Department of Pulmonology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Borecki, Ingrid B" sort="Borecki, Ingrid B" uniqKey="Borecki I" first="Ingrid B." last="Borecki">Ingrid B. Borecki</name><affiliation><nlm:aff id="A47">Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:aff></affiliation></author><author><name sortKey="Deloukas, Panos" sort="Deloukas, Panos" uniqKey="Deloukas P" first="Panos" last="Deloukas">Panos Deloukas</name><affiliation><nlm:aff id="A22">Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A50">William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A339">Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, 21589 Jeddah, Saudi Arabia.</nlm:aff></affiliation></author><author><name sortKey="Fox, Caroline S" sort="Fox, Caroline S" uniqKey="Fox C" first="Caroline S." last="Fox">Caroline S. Fox</name><affiliation><nlm:aff id="A127">National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts 01702, USA.</nlm:aff></affiliation></author><author><name sortKey="Heid, Iris M" sort="Heid, Iris M" uniqKey="Heid I" first="Iris M." last="Heid">Iris M. Heid</name><affiliation><nlm:aff id="A23">Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, D-93053 Regensburg, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A85">Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.</nlm:aff></affiliation></author><author><name sortKey="O Onnell, Jeffrey R" sort="O Onnell, Jeffrey R" uniqKey="O Onnell J" first="Jeffrey R." last="O Onnell">Jeffrey R. O Onnell</name><affiliation><nlm:aff id="A295">Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A296">Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.</nlm:aff></affiliation></author><author><name sortKey="Strachan, David P" sort="Strachan, David P" uniqKey="Strachan D" first="David P." last="Strachan">David P. Strachan</name><affiliation><nlm:aff id="A340">Division of Population Health Sciences & Education, St George’s, University of London, London SW17 0RE, UK.</nlm:aff></affiliation></author><author><name sortKey="Stefansson, Kari" sort="Stefansson, Kari" uniqKey="Stefansson K" first="Kari" last="Stefansson">Kari Stefansson</name><affiliation><nlm:aff id="A171">deCODE Genetics, Amgen Inc., Reykjavik 101, Iceland.</nlm:aff></affiliation><affiliation><nlm:aff id="A327">Faculty of Medicine, University of Iceland, Reykjavik 101, Iceland.</nlm:aff></affiliation></author><author><name sortKey="Van Duijn, Cornelia M" sort="Van Duijn, Cornelia M" uniqKey="Van Duijn C" first="Cornelia M." last="Van Duijn">Cornelia M. Van Duijn</name><affiliation><nlm:aff id="A32">Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC University Medical Center, 3015 GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A58">Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A59">Department of Epidemiology, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A84">Center for Medical Sytems Biology, 2300 RC Leiden, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Abecasis, Goncalo R" sort="Abecasis, Goncalo R" uniqKey="Abecasis G" first="Gonçalo R." last="Abecasis">Gonçalo R. Abecasis</name><affiliation><nlm:aff id="A1">Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation></author><author><name sortKey="Franke, Lude" sort="Franke, Lude" uniqKey="Franke L" first="Lude" last="Franke">Lude Franke</name><affiliation><nlm:aff id="A29">Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Frayling, Timothy M" sort="Frayling, Timothy M" uniqKey="Frayling T" first="Timothy M." last="Frayling">Timothy M. Frayling</name><affiliation><nlm:aff id="A24">Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK.</nlm:aff></affiliation></author><author><name sortKey="Mccarthy, Mark I" sort="Mccarthy, Mark I" uniqKey="Mccarthy M" first="Mark I." last="Mccarthy">Mark I. Mccarthy</name><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A64">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A341">Oxford NIHR Biomedical Research Centre, Oxford University Hospitals NHS Trust, Oxford OX3 7LJ, UK.</nlm:aff></affiliation></author><author><name sortKey="Visscher, Peter M" sort="Visscher, Peter M" uniqKey="Visscher P" first="Peter M." last="Visscher">Peter M. Visscher</name><affiliation><nlm:aff id="A11">Queensland Brain Institute, The University of Queensland, Brisbane 4072, Australia.</nlm:aff></affiliation><affiliation><nlm:aff id="A12">The University of Queensland Diamantina Institute, The Translation Research Institute, Brisbane 4012, Australia.</nlm:aff></affiliation></author><author><name sortKey="Scherag, Andre" sort="Scherag, Andre" uniqKey="Scherag A" first="André" last="Scherag">André Scherag</name><affiliation><nlm:aff id="A63">Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen, 45147 Essen, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A342">Clinical Epidemiology, Integrated Research and Treatment Center, Center for Sepsis Control and Care (CSCC), Jena University Hospital, 07743 Jena, Germany.</nlm:aff></affiliation></author><author><name sortKey="Willer, Cristen J" sort="Willer, Cristen J" uniqKey="Willer C" first="Cristen J." last="Willer">Cristen J. Willer</name><affiliation><nlm:aff id="A28">Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A30">Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A343">Department of Human Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation></author><author><name sortKey="Boehnke, Michael" sort="Boehnke, Michael" uniqKey="Boehnke M" first="Michael" last="Boehnke">Michael Boehnke</name><affiliation><nlm:aff id="A1">Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation></author><author><name sortKey="Mohlke, Karen L" sort="Mohlke, Karen L" uniqKey="Mohlke K" first="Karen L." last="Mohlke">Karen L. Mohlke</name><affiliation><nlm:aff id="A10">Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.</nlm:aff></affiliation></author><author><name sortKey="Lindgren, Cecilia M" sort="Lindgren, Cecilia M" uniqKey="Lindgren C" first="Cecilia M." last="Lindgren">Cecilia M. Lindgren</name><affiliation><nlm:aff id="A6">Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation></author><author><name sortKey="Beckmann, Jacques S" sort="Beckmann, Jacques S" uniqKey="Beckmann J" first="Jacques S." last="Beckmann">Jacques S. Beckmann</name><affiliation><nlm:aff id="A20">Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland.</nlm:aff></affiliation><affiliation><nlm:aff id="A21">Department of Medical Genetics, University of Lausanne, Lausanne 1005, Switzerland.</nlm:aff></affiliation><affiliation><nlm:aff id="A344">Service of Medical Genetics, CHUV University Hospital, 1011 Lausanne, Switzerland.</nlm:aff></affiliation></author><author><name sortKey="Barroso, Ines" sort="Barroso, Ines" uniqKey="Barroso I" first="Inês" last="Barroso">Inês Barroso</name><affiliation><nlm:aff id="A22">Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A345">University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge CB2 OQQ, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A346">NIHR Cambridge Biomedical Research Centre, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge CB2 OQQ, UK.</nlm:aff></affiliation></author><author><name sortKey="North, Kari E" sort="North, Kari E" uniqKey="North K" first="Kari E." last="North">Kari E. North</name><affiliation><nlm:aff id="A4">Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A347">Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.</nlm:aff></affiliation></author><author><name sortKey="Ingelsson, Erik" sort="Ingelsson, Erik" uniqKey="Ingelsson E" first="Erik" last="Ingelsson">Erik Ingelsson</name><affiliation><nlm:aff id="A16">Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.</nlm:aff></affiliation><affiliation><nlm:aff id="A17">Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala 75185, Sweden.</nlm:aff></affiliation><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation></author><author><name sortKey="Hirschhorn, Joel N" sort="Hirschhorn, Joel N" uniqKey="Hirschhorn J" first="Joel N." last="Hirschhorn">Joel N. Hirschhorn</name><affiliation><nlm:aff id="A5">Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children’s Hospital, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A6">Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A7">Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation></author><author><name sortKey="Loos, Ruth J F" sort="Loos, Ruth J F" uniqKey="Loos R" first="Ruth J. F." last="Loos">Ruth J. F. Loos</name><affiliation><nlm:aff id="A9">MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A55">The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A145">The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A348">The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:aff></affiliation></author><author><name sortKey="Speliotes, Elizabeth K" sort="Speliotes, Elizabeth K" uniqKey="Speliotes E" first="Elizabeth K." last="Speliotes">Elizabeth K. Speliotes</name><affiliation><nlm:aff id="A2">Department of Internal Medicine, Division of Gastroenterology, and Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">25673413</idno><idno type="pmc">4382211</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382211</idno><idno type="RBID">PMC:4382211</idno><idno type="doi">10.1038/nature14177</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">001D38</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001D38</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Genetic studies of body mass index yield new insights for obesity biology</title><author><name sortKey="Locke, Adam E" sort="Locke, Adam E" uniqKey="Locke A" first="Adam E." last="Locke">Adam E. Locke</name><affiliation><nlm:aff id="A1">Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation></author><author><name sortKey="Kahali, Bratati" sort="Kahali, Bratati" uniqKey="Kahali B" first="Bratati" last="Kahali">Bratati Kahali</name><affiliation><nlm:aff id="A2">Department of Internal Medicine, Division of Gastroenterology, and Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation></author><author><name sortKey="Berndt, Sonja I" sort="Berndt, Sonja I" uniqKey="Berndt S" first="Sonja I." last="Berndt">Sonja I. Berndt</name><affiliation><nlm:aff id="A3">Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.</nlm:aff></affiliation></author><author><name sortKey="Justice, Anne E" sort="Justice, Anne E" uniqKey="Justice A" first="Anne E." last="Justice">Anne E. Justice</name><affiliation><nlm:aff id="A4">Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.</nlm:aff></affiliation></author><author><name sortKey="Pers, Tune H" sort="Pers, Tune H" uniqKey="Pers T" first="Tune H." last="Pers">Tune H. Pers</name><affiliation><nlm:aff id="A5">Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children’s Hospital, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A6">Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A7">Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A8">Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby 2800, Denmark.</nlm:aff></affiliation></author><author><name sortKey="Day, Felix R" sort="Day, Felix R" uniqKey="Day F" first="Felix R." last="Day">Felix R. Day</name><affiliation><nlm:aff id="A9">MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:aff></affiliation></author><author><name sortKey="Powell, Corey" sort="Powell, Corey" uniqKey="Powell C" first="Corey" last="Powell">Corey Powell</name><affiliation><nlm:aff id="A2">Department of Internal Medicine, Division of Gastroenterology, and Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation></author><author><name sortKey="Vedantam, Sailaja" sort="Vedantam, Sailaja" uniqKey="Vedantam S" first="Sailaja" last="Vedantam">Sailaja Vedantam</name><affiliation><nlm:aff id="A5">Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children’s Hospital, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A6">Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.</nlm:aff></affiliation></author><author><name sortKey="Buchkovich, Martin L" sort="Buchkovich, Martin L" uniqKey="Buchkovich M" first="Martin L." last="Buchkovich">Martin L. Buchkovich</name><affiliation><nlm:aff id="A10">Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.</nlm:aff></affiliation></author><author><name sortKey="Yang, Jian" sort="Yang, Jian" uniqKey="Yang J" first="Jian" last="Yang">Jian Yang</name><affiliation><nlm:aff id="A11">Queensland Brain Institute, The University of Queensland, Brisbane 4072, Australia.</nlm:aff></affiliation><affiliation><nlm:aff id="A12">The University of Queensland Diamantina Institute, The Translation Research Institute, Brisbane 4012, Australia.</nlm:aff></affiliation></author><author><name sortKey="Croteau Chonka, Damien C" sort="Croteau Chonka, Damien C" uniqKey="Croteau Chonka D" first="Damien C." last="Croteau-Chonka">Damien C. Croteau-Chonka</name><affiliation><nlm:aff id="A10">Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A13">Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation></author><author><name sortKey="Esko, Tonu" sort="Esko, Tonu" uniqKey="Esko T" first="Tonu" last="Esko">Tonu Esko</name><affiliation><nlm:aff id="A5">Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children’s Hospital, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A6">Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A7">Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A14">Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.</nlm:aff></affiliation></author><author><name sortKey="Fall, Tove" sort="Fall, Tove" uniqKey="Fall T" first="Tove" last="Fall">Tove Fall</name><affiliation><nlm:aff id="A15">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden.</nlm:aff></affiliation><affiliation><nlm:aff id="A16">Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.</nlm:aff></affiliation><affiliation><nlm:aff id="A17">Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala 75185, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Ferreira, Teresa" sort="Ferreira, Teresa" uniqKey="Ferreira T" first="Teresa" last="Ferreira">Teresa Ferreira</name><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation></author><author><name sortKey="Gustafsson, Stefan" sort="Gustafsson, Stefan" uniqKey="Gustafsson S" first="Stefan" last="Gustafsson">Stefan Gustafsson</name><affiliation><nlm:aff id="A16">Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.</nlm:aff></affiliation><affiliation><nlm:aff id="A17">Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala 75185, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Kutalik, Zoltan" sort="Kutalik, Zoltan" uniqKey="Kutalik Z" first="Zoltán" last="Kutalik">Zoltán Kutalik</name><affiliation><nlm:aff id="A19">Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne 1010, Switzerland.</nlm:aff></affiliation><affiliation><nlm:aff id="A20">Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland.</nlm:aff></affiliation><affiliation><nlm:aff id="A21">Department of Medical Genetics, University of Lausanne, Lausanne 1005, Switzerland.</nlm:aff></affiliation></author><author><name sortKey="Luan, Jian N" sort="Luan, Jian N" uniqKey="Luan J" first="Jian N" last="Luan">Jian N Luan</name><affiliation><nlm:aff id="A9">MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:aff></affiliation></author><author><name sortKey="M Gi, Reedik" sort="M Gi, Reedik" uniqKey="M Gi R" first="Reedik" last="M Gi">Reedik M Gi</name><affiliation><nlm:aff id="A14">Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.</nlm:aff></affiliation><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation></author><author><name sortKey="Randall, Joshua C" sort="Randall, Joshua C" uniqKey="Randall J" first="Joshua C." last="Randall">Joshua C. Randall</name><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A22">Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.</nlm:aff></affiliation></author><author><name sortKey="Winkler, Thomas W" sort="Winkler, Thomas W" uniqKey="Winkler T" first="Thomas W." last="Winkler">Thomas W. Winkler</name><affiliation><nlm:aff id="A23">Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, D-93053 Regensburg, Germany.</nlm:aff></affiliation></author><author><name sortKey="Wood, Andrew R" sort="Wood, Andrew R" uniqKey="Wood A" first="Andrew R." last="Wood">Andrew R. Wood</name><affiliation><nlm:aff id="A24">Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK.</nlm:aff></affiliation></author><author><name sortKey="Workalemahu, Tsegaselassie" sort="Workalemahu, Tsegaselassie" uniqKey="Workalemahu T" first="Tsegaselassie" last="Workalemahu">Tsegaselassie Workalemahu</name><affiliation><nlm:aff id="A25">Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation></author><author><name sortKey="Faul, Jessica D" sort="Faul, Jessica D" uniqKey="Faul J" first="Jessica D." last="Faul">Jessica D. Faul</name><affiliation><nlm:aff id="A26">Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan 48104, USA.</nlm:aff></affiliation></author><author><name sortKey="Smith, Jennifer A" sort="Smith, Jennifer A" uniqKey="Smith J" first="Jennifer A." last="Smith">Jennifer A. Smith</name><affiliation><nlm:aff id="A27">Department of Epidemiology, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation></author><author><name sortKey="Zhao, Jing Hua" sort="Zhao, Jing Hua" uniqKey="Zhao J" first="Jing Hua" last="Zhao">Jing Hua Zhao</name><affiliation><nlm:aff id="A9">MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:aff></affiliation></author><author><name sortKey="Zhao, Wei" sort="Zhao, Wei" uniqKey="Zhao W" first="Wei" last="Zhao">Wei Zhao</name><affiliation><nlm:aff id="A27">Department of Epidemiology, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation></author><author><name sortKey="Chen, Jin" sort="Chen, Jin" uniqKey="Chen J" first="Jin" last="Chen">Jin Chen</name><affiliation><nlm:aff id="A28">Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation></author><author><name sortKey="Fehrmann, Rudolf" sort="Fehrmann, Rudolf" uniqKey="Fehrmann R" first="Rudolf" last="Fehrmann">Rudolf Fehrmann</name><affiliation><nlm:aff id="A29">Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Hedman, Sa K" sort="Hedman, Sa K" uniqKey="Hedman " first=" Sa K." last="Hedman"> Sa K. Hedman</name><affiliation><nlm:aff id="A16">Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.</nlm:aff></affiliation><affiliation><nlm:aff id="A17">Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala 75185, Sweden.</nlm:aff></affiliation><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation></author><author><name sortKey="Karjalainen, Juha" sort="Karjalainen, Juha" uniqKey="Karjalainen J" first="Juha" last="Karjalainen">Juha Karjalainen</name><affiliation><nlm:aff id="A29">Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Schmidt, Ellen M" sort="Schmidt, Ellen M" uniqKey="Schmidt E" first="Ellen M." last="Schmidt">Ellen M. Schmidt</name><affiliation><nlm:aff id="A30">Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation></author><author><name sortKey="Absher, Devin" sort="Absher, Devin" uniqKey="Absher D" first="Devin" last="Absher">Devin Absher</name><affiliation><nlm:aff id="A31">HudsonAlpha Institute for Biotechnology, Huntsville, Alabama 35806, USA.</nlm:aff></affiliation></author><author><name sortKey="Amin, Najaf" sort="Amin, Najaf" uniqKey="Amin N" first="Najaf" last="Amin">Najaf Amin</name><affiliation><nlm:aff id="A32">Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC University Medical Center, 3015 GE Rotterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Anderson, Denise" sort="Anderson, Denise" uniqKey="Anderson D" first="Denise" last="Anderson">Denise Anderson</name><affiliation><nlm:aff id="A33">Telethon Institute for Child Health Research, Centre for Child Health Research, The University of Western Australia, Perth, Western Australia 6008, Australia.</nlm:aff></affiliation></author><author><name sortKey="Beekman, Marian" sort="Beekman, Marian" uniqKey="Beekman M" first="Marian" last="Beekman">Marian Beekman</name><affiliation><nlm:aff id="A34">Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A35">Department of Molecular Epidemiology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Bolton, Jennifer L" sort="Bolton, Jennifer L" uniqKey="Bolton J" first="Jennifer L." last="Bolton">Jennifer L. Bolton</name><affiliation><nlm:aff id="A36">Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK.</nlm:aff></affiliation></author><author><name sortKey="Bragg Gresham, Jennifer L" sort="Bragg Gresham, Jennifer L" uniqKey="Bragg Gresham J" first="Jennifer L." last="Bragg-Gresham">Jennifer L. Bragg-Gresham</name><affiliation><nlm:aff id="A1">Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A37">Kidney Epidemiology and Cost Center, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation></author><author><name sortKey="Buyske, Steven" sort="Buyske, Steven" uniqKey="Buyske S" first="Steven" last="Buyske">Steven Buyske</name><affiliation><nlm:aff id="A38">Department of Statistics & Biostatistics, Rutgers University, Piscataway, New Jersey 08854, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A39">Department of Genetics, Rutgers University, Piscataway, New Jersey 08854, USA.</nlm:aff></affiliation></author><author><name sortKey="Demirkan, Ayse" sort="Demirkan, Ayse" uniqKey="Demirkan A" first="Ayse" last="Demirkan">Ayse Demirkan</name><affiliation><nlm:aff id="A32">Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC University Medical Center, 3015 GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A40">Department of Human Genetics, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Deng, Guohong" sort="Deng, Guohong" uniqKey="Deng G" first="Guohong" last="Deng">Guohong Deng</name><affiliation><nlm:aff id="A41">Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A42">Department of Gastroenterology and Hepatology, Imperial College London, London W2 1PG, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A43">Institute of infectious Diseases, Southwest Hospital, Third Military Medical University, Chongqing, China.</nlm:aff></affiliation></author><author><name sortKey="Ehret, Georg B" sort="Ehret, Georg B" uniqKey="Ehret G" first="Georg B." last="Ehret">Georg B. Ehret</name><affiliation><nlm:aff id="A44">Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A45">Cardiology, Department of Specialties of Internal Medicine, Geneva University Hospital, Geneva 1211, Switzerland.</nlm:aff></affiliation></author><author><name sortKey="Feenstra, Bjarke" sort="Feenstra, Bjarke" uniqKey="Feenstra B" first="Bjarke" last="Feenstra">Bjarke Feenstra</name><affiliation><nlm:aff id="A46">Department of Epidemiology Research, Statens Serum Institut, Copenhagen DK-2300, Denmark.</nlm:aff></affiliation></author><author><name sortKey="Feitosa, Mary F" sort="Feitosa, Mary F" uniqKey="Feitosa M" first="Mary F." last="Feitosa">Mary F. Feitosa</name><affiliation><nlm:aff id="A47">Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:aff></affiliation></author><author><name sortKey="Fischer, Krista" sort="Fischer, Krista" uniqKey="Fischer K" first="Krista" last="Fischer">Krista Fischer</name><affiliation><nlm:aff id="A14">Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.</nlm:aff></affiliation></author><author><name sortKey="Goel, Anuj" sort="Goel, Anuj" uniqKey="Goel A" first="Anuj" last="Goel">Anuj Goel</name><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A48">Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, UK.</nlm:aff></affiliation></author><author><name sortKey="Gong, Jian" sort="Gong, Jian" uniqKey="Gong J" first="Jian" last="Gong">Jian Gong</name><affiliation><nlm:aff id="A49">Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.</nlm:aff></affiliation></author><author><name sortKey="Jackson, Anne U" sort="Jackson, Anne U" uniqKey="Jackson A" first="Anne U." last="Jackson">Anne U. Jackson</name><affiliation><nlm:aff id="A1">Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation></author><author><name sortKey="Kanoni, Stavroula" sort="Kanoni, Stavroula" uniqKey="Kanoni S" first="Stavroula" last="Kanoni">Stavroula Kanoni</name><affiliation><nlm:aff id="A50">William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.</nlm:aff></affiliation></author><author><name sortKey="Kleber, Marcus E" sort="Kleber, Marcus E" uniqKey="Kleber M" first="Marcus E." last="Kleber">Marcus E. Kleber</name><affiliation><nlm:aff id="A51">Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, D-68187 Mannheim, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A52">Department of Internal Medicine II, Ulm University Medical Centre, D-89081 Ulm, Germany.</nlm:aff></affiliation></author><author><name sortKey="Kristiansson, Kati" sort="Kristiansson, Kati" uniqKey="Kristiansson K" first="Kati" last="Kristiansson">Kati Kristiansson</name><affiliation><nlm:aff id="A53">National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:aff></affiliation></author><author><name sortKey="Lim, Unhee" sort="Lim, Unhee" uniqKey="Lim U" first="Unhee" last="Lim">Unhee Lim</name><affiliation><nlm:aff id="A54">Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96813, USA.</nlm:aff></affiliation></author><author><name sortKey="Lotay, Vaneet" sort="Lotay, Vaneet" uniqKey="Lotay V" first="Vaneet" last="Lotay">Vaneet Lotay</name><affiliation><nlm:aff id="A55">The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:aff></affiliation></author><author><name sortKey="Mangino, Massimo" sort="Mangino, Massimo" uniqKey="Mangino M" first="Massimo" last="Mangino">Massimo Mangino</name><affiliation><nlm:aff id="A56">Department of Twin Research and Genetic Epidemiology, King’s College London, London SE1 7EH, UK.</nlm:aff></affiliation></author><author><name sortKey="Leach, Irene Mateo" sort="Leach, Irene Mateo" uniqKey="Leach I" first="Irene Mateo" last="Leach">Irene Mateo Leach</name><affiliation><nlm:aff id="A57">Department of Cardiology, University Medical Center Groningen, University of Groningen, 9700RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Medina Gomez, Carolina" sort="Medina Gomez, Carolina" uniqKey="Medina Gomez C" first="Carolina" last="Medina-Gomez">Carolina Medina-Gomez</name><affiliation><nlm:aff id="A58">Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A59">Department of Epidemiology, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A60">Department of Internal Medicine, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Medland, Sarah E" sort="Medland, Sarah E" uniqKey="Medland S" first="Sarah E." last="Medland">Sarah E. Medland</name><affiliation><nlm:aff id="A61">QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4006, Australia.</nlm:aff></affiliation></author><author><name sortKey="Nalls, Michael A" sort="Nalls, Michael A" uniqKey="Nalls M" first="Michael A." last="Nalls">Michael A. Nalls</name><affiliation><nlm:aff id="A62">Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892, USA.</nlm:aff></affiliation></author><author><name sortKey="Palmer, Cameron D" sort="Palmer, Cameron D" uniqKey="Palmer C" first="Cameron D." last="Palmer">Cameron D. Palmer</name><affiliation><nlm:aff id="A5">Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children’s Hospital, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A6">Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.</nlm:aff></affiliation></author><author><name sortKey="Pasko, Dorota" sort="Pasko, Dorota" uniqKey="Pasko D" first="Dorota" last="Pasko">Dorota Pasko</name><affiliation><nlm:aff id="A24">Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK.</nlm:aff></affiliation></author><author><name sortKey="Pechlivanis, Sonali" sort="Pechlivanis, Sonali" uniqKey="Pechlivanis S" first="Sonali" last="Pechlivanis">Sonali Pechlivanis</name><affiliation><nlm:aff id="A63">Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen, 45147 Essen, Germany.</nlm:aff></affiliation></author><author><name sortKey="Peters, Marjolein J" sort="Peters, Marjolein J" uniqKey="Peters M" first="Marjolein J." last="Peters">Marjolein J. Peters</name><affiliation><nlm:aff id="A58">Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A60">Department of Internal Medicine, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Prokopenko, Inga" sort="Prokopenko, Inga" uniqKey="Prokopenko I" first="Inga" last="Prokopenko">Inga Prokopenko</name><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A64">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A65">Department of Genomics of Common Disease, School of Public Health, Imperial College London, Hammersmith Hospital, London W12 0NN, UK.</nlm:aff></affiliation></author><author><name sortKey="Shungin, Dmitry" sort="Shungin, Dmitry" uniqKey="Shungin D" first="Dmitry" last="Shungin">Dmitry Shungin</name><affiliation><nlm:aff id="A66">Department of Clinical Sciences, Genetic & Molecular Epidemiology Unit, Lund University Diabetes Center, Skåne University Hosptial, Malmö 205 02, Sweden.</nlm:aff></affiliation><affiliation><nlm:aff id="A67">Department of Public Health and Clinical Medicine, Unit of Medicine, Umeå University, Umeå 901 87, Sweden.</nlm:aff></affiliation><affiliation><nlm:aff id="A68">Department of Odontology, Umeå University, Umeå 901 85, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Stan Kova, Alena" sort="Stan Kova, Alena" uniqKey="Stan Kova A" first="Alena" last="Stan Ková">Alena Stan Ková</name><affiliation><nlm:aff id="A69">University of Eastern Finland, FI-70210 Kuopio, Finland.</nlm:aff></affiliation></author><author><name sortKey="Strawbridge, Rona J" sort="Strawbridge, Rona J" uniqKey="Strawbridge R" first="Rona J." last="Strawbridge">Rona J. Strawbridge</name><affiliation><nlm:aff id="A70">Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm 17176, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Sung, Yun Ju" sort="Sung, Yun Ju" uniqKey="Sung Y" first="Yun Ju" last="Sung">Yun Ju Sung</name><affiliation><nlm:aff id="A71">Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:aff></affiliation></author><author><name sortKey="Tanaka, Toshiko" sort="Tanaka, Toshiko" uniqKey="Tanaka T" first="Toshiko" last="Tanaka">Toshiko Tanaka</name><affiliation><nlm:aff id="A72">Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland 21225, USA.</nlm:aff></affiliation></author><author><name sortKey="Teumer, Alexander" sort="Teumer, Alexander" uniqKey="Teumer A" first="Alexander" last="Teumer">Alexander Teumer</name><affiliation><nlm:aff id="A73">Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, D-17475 Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Trompet, Stella" sort="Trompet, Stella" uniqKey="Trompet S" first="Stella" last="Trompet">Stella Trompet</name><affiliation><nlm:aff id="A74">Department of Cardiology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A75">Department of Gerontology and Geriatrics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Van Der Laan, Sander W" sort="Van Der Laan, Sander W" uniqKey="Van Der Laan S" first="Sander W." last="Van Der Laan">Sander W. Van Der Laan</name><affiliation><nlm:aff id="A76">Experimental Cardiology Laboratory, Division Heart and Lungs, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Van Setten, Jessica" sort="Van Setten, Jessica" uniqKey="Van Setten J" first="Jessica" last="Van Setten">Jessica Van Setten</name><affiliation><nlm:aff id="A77">Department of Medical Genetics, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Van Vliet Ostaptchouk, Jana V" sort="Van Vliet Ostaptchouk, Jana V" uniqKey="Van Vliet Ostaptchouk J" first="Jana V." last="Van Vliet-Ostaptchouk">Jana V. Van Vliet-Ostaptchouk</name><affiliation><nlm:aff id="A78">Department of Endocrinology, University of Groningen, University Medical Center Groningen, 9700 RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Wang, Zhaoming" sort="Wang, Zhaoming" uniqKey="Wang Z" first="Zhaoming" last="Wang">Zhaoming Wang</name><affiliation><nlm:aff id="A3">Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A79">Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland 21702, USA.</nlm:aff></affiliation></author><author><name sortKey="Yengo, Loic" sort="Yengo, Loic" uniqKey="Yengo L" first="Loïc" last="Yengo">Loïc Yengo</name><affiliation><nlm:aff id="A80">CNRS UMR 8199, F-59019 Lille, France.</nlm:aff></affiliation><affiliation><nlm:aff id="A81">European Genomic Institute for Diabetes, F-59000 Lille, France.</nlm:aff></affiliation><affiliation><nlm:aff id="A82">Université de Lille 2, F-59000 Lille, France.</nlm:aff></affiliation></author><author><name sortKey="Zhang, Weihua" sort="Zhang, Weihua" uniqKey="Zhang W" first="Weihua" last="Zhang">Weihua Zhang</name><affiliation><nlm:aff id="A41">Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A83">Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.</nlm:aff></affiliation></author><author><name sortKey="Isaacs, Aaron" sort="Isaacs, Aaron" uniqKey="Isaacs A" first="Aaron" last="Isaacs">Aaron Isaacs</name><affiliation><nlm:aff id="A32">Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC University Medical Center, 3015 GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A84">Center for Medical Sytems Biology, 2300 RC Leiden, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Albrecht, Eva" sort="Albrecht, Eva" uniqKey="Albrecht E" first="Eva" last="Albrecht">Eva Albrecht</name><affiliation><nlm:aff id="A85">Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.</nlm:aff></affiliation></author><author><name sortKey=" Rnlov, Johan" sort=" Rnlov, Johan" uniqKey=" Rnlov J" first="Johan" last=" Rnlöv">Johan Rnlöv</name><affiliation><nlm:aff id="A16">Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.</nlm:aff></affiliation><affiliation><nlm:aff id="A17">Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala 75185, Sweden.</nlm:aff></affiliation><affiliation><nlm:aff id="A86">School of Health and Social Studies, Dalarna University, SE-791 88 Falun, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Arscott, Gillian M" sort="Arscott, Gillian M" uniqKey="Arscott G" first="Gillian M." last="Arscott">Gillian M. Arscott</name><affiliation><nlm:aff id="A87">PathWest Laboratory Medicine of Western Australia, Nedlands, Western Australia 6009, Australia.</nlm:aff></affiliation></author><author><name sortKey="Attwood, Antony P" sort="Attwood, Antony P" uniqKey="Attwood A" first="Antony P." last="Attwood">Antony P. Attwood</name><affiliation><nlm:aff id="A88">Department of Haematology, University of Cambridge, Cambridge CB2 0PT, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A89">NHS Blood and Transplant, Cambridge CB2 0PT, UK.</nlm:aff></affiliation></author><author><name sortKey="Bandinelli, Stefania" sort="Bandinelli, Stefania" uniqKey="Bandinelli S" first="Stefania" last="Bandinelli">Stefania Bandinelli</name><affiliation><nlm:aff id="A90">Geriatric Unit, Azienda Sanitaria Firenze (ASF), 50125 Florence, Italy.</nlm:aff></affiliation></author><author><name sortKey="Barrett, Amy" sort="Barrett, Amy" uniqKey="Barrett A" first="Amy" last="Barrett">Amy Barrett</name><affiliation><nlm:aff id="A64">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.</nlm:aff></affiliation></author><author><name sortKey="Bas, Isabelita N" sort="Bas, Isabelita N" uniqKey="Bas I" first="Isabelita N." last="Bas">Isabelita N. Bas</name><affiliation><nlm:aff id="A91">USC-Office of Population Studies Foundation, Inc., University of San Carlos, Cebu City 6000, Philippines.</nlm:aff></affiliation></author><author><name sortKey="Bellis, Claire" sort="Bellis, Claire" uniqKey="Bellis C" first="Claire" last="Bellis">Claire Bellis</name><affiliation><nlm:aff id="A92">Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas 78227, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A93">Genomics Research Centre, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland 4001, Australia.</nlm:aff></affiliation></author><author><name sortKey="Bennett, Amanda J" sort="Bennett, Amanda J" uniqKey="Bennett A" first="Amanda J." last="Bennett">Amanda J. Bennett</name><affiliation><nlm:aff id="A64">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.</nlm:aff></affiliation></author><author><name sortKey="Berne, Christian" sort="Berne, Christian" uniqKey="Berne C" first="Christian" last="Berne">Christian Berne</name><affiliation><nlm:aff id="A94">Department of Medical Sciences, Endocrinology, Diabetes and Metabolism, Uppsala University, Uppsala 75185, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Blagieva, Roza" sort="Blagieva, Roza" uniqKey="Blagieva R" first="Roza" last="Blagieva">Roza Blagieva</name><affiliation><nlm:aff id="A95">Division of Endocrinology, Diabetes and Metabolism, Ulm University Medical Centre, D-89081 Ulm, Germany.</nlm:aff></affiliation></author><author><name sortKey="Bluher, Matthias" sort="Bluher, Matthias" uniqKey="Bluher M" first="Matthias" last="Blüher">Matthias Blüher</name><affiliation><nlm:aff id="A96">Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, D-04103 Leipzig, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A97">Department of Medicine, University of Leipzig, D-04103 Leipzig, Germany.</nlm:aff></affiliation></author><author><name sortKey="Bohringer, Stefan" sort="Bohringer, Stefan" uniqKey="Bohringer S" first="Stefan" last="Böhringer">Stefan Böhringer</name><affiliation><nlm:aff id="A34">Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A98">Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Bonnycastle, Lori L" sort="Bonnycastle, Lori L" uniqKey="Bonnycastle L" first="Lori L." last="Bonnycastle">Lori L. Bonnycastle</name><affiliation><nlm:aff id="A99">Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA.</nlm:aff></affiliation></author><author><name sortKey="Bottcher, Yvonne" sort="Bottcher, Yvonne" uniqKey="Bottcher Y" first="Yvonne" last="Böttcher">Yvonne Böttcher</name><affiliation><nlm:aff id="A96">Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, D-04103 Leipzig, Germany.</nlm:aff></affiliation></author><author><name sortKey="Boyd, Heather A" sort="Boyd, Heather A" uniqKey="Boyd H" first="Heather A." last="Boyd">Heather A. Boyd</name><affiliation><nlm:aff id="A46">Department of Epidemiology Research, Statens Serum Institut, Copenhagen DK-2300, Denmark.</nlm:aff></affiliation></author><author><name sortKey="Bruinenberg, Marcel" sort="Bruinenberg, Marcel" uniqKey="Bruinenberg M" first="Marcel" last="Bruinenberg">Marcel Bruinenberg</name><affiliation><nlm:aff id="A100">LifeLines Cohort Study, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Caspersen, Ida H" sort="Caspersen, Ida H" uniqKey="Caspersen I" first="Ida H." last="Caspersen">Ida H. Caspersen</name><affiliation><nlm:aff id="A101">Department of Biology, Norwegian University of Science and Technology, 7491 Trondheim, Norway.</nlm:aff></affiliation></author><author><name sortKey="Chen, Yii Der Ida" sort="Chen, Yii Der Ida" uniqKey="Chen Y" first="Yii-Der Ida" last="Chen">Yii-Der Ida Chen</name><affiliation><nlm:aff id="A102">Department of Pediatrics, University of California Los Angeles, Torrance, California 90502, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A103">Transgenomics Institute, Los Angeles Biomedical Research Institute, Torrance, California 90502, USA.</nlm:aff></affiliation></author><author><name sortKey="Clarke, Robert" sort="Clarke, Robert" uniqKey="Clarke R" first="Robert" last="Clarke">Robert Clarke</name><affiliation><nlm:aff id="A104">Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.</nlm:aff></affiliation></author><author><name sortKey="Daw, E Warwick" sort="Daw, E Warwick" uniqKey="Daw E" first="E. Warwick" last="Daw">E. Warwick Daw</name><affiliation><nlm:aff id="A47">Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:aff></affiliation></author><author><name sortKey="De Craen, Anton J M" sort="De Craen, Anton J M" uniqKey="De Craen A" first="Anton J. M." last="De Craen">Anton J. M. De Craen</name><affiliation><nlm:aff id="A75">Department of Gerontology and Geriatrics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Delgado, Graciela" sort="Delgado, Graciela" uniqKey="Delgado G" first="Graciela" last="Delgado">Graciela Delgado</name><affiliation><nlm:aff id="A51">Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, D-68187 Mannheim, Germany.</nlm:aff></affiliation></author><author><name sortKey="Dimitriou, Maria" sort="Dimitriou, Maria" uniqKey="Dimitriou M" first="Maria" last="Dimitriou">Maria Dimitriou</name><affiliation><nlm:aff id="A105">Department of Dietetics-Nutrition, Harokopio University, 17671 Athens, Greece.</nlm:aff></affiliation></author><author><name sortKey="Doney, Alex S F" sort="Doney, Alex S F" uniqKey="Doney A" first="Alex S. F." last="Doney">Alex S. F. Doney</name><affiliation><nlm:aff id="A106">Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.</nlm:aff></affiliation></author><author><name sortKey="Eklund, Niina" sort="Eklund, Niina" uniqKey="Eklund N" first="Niina" last="Eklund">Niina Eklund</name><affiliation><nlm:aff id="A53">National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A107">Institute for Molecular Medicine, University of Helsinki, FI-00014 Helsinki, Finland.</nlm:aff></affiliation></author><author><name sortKey="Estrada, Karol" sort="Estrada, Karol" uniqKey="Estrada K" first="Karol" last="Estrada">Karol Estrada</name><affiliation><nlm:aff id="A6">Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A60">Department of Internal Medicine, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A108">Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA.</nlm:aff></affiliation></author><author><name sortKey="Eury, Elodie" sort="Eury, Elodie" uniqKey="Eury E" first="Elodie" last="Eury">Elodie Eury</name><affiliation><nlm:aff id="A80">CNRS UMR 8199, F-59019 Lille, France.</nlm:aff></affiliation><affiliation><nlm:aff id="A81">European Genomic Institute for Diabetes, F-59000 Lille, France.</nlm:aff></affiliation><affiliation><nlm:aff id="A82">Université de Lille 2, F-59000 Lille, France.</nlm:aff></affiliation></author><author><name sortKey="Folkersen, Lasse" sort="Folkersen, Lasse" uniqKey="Folkersen L" first="Lasse" last="Folkersen">Lasse Folkersen</name><affiliation><nlm:aff id="A70">Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm 17176, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Fraser, Ross M" sort="Fraser, Ross M" uniqKey="Fraser R" first="Ross M." last="Fraser">Ross M. Fraser</name><affiliation><nlm:aff id="A36">Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK.</nlm:aff></affiliation></author><author><name sortKey="Garcia, Melissa E" sort="Garcia, Melissa E" uniqKey="Garcia M" first="Melissa E." last="Garcia">Melissa E. Garcia</name><affiliation><nlm:aff id="A109">Laboratory of Epidemiology and Population Sciences, National Institute on Aging, NIH, Bethesda, Maryland 20892, USA.</nlm:aff></affiliation></author><author><name sortKey="Geller, Frank" sort="Geller, Frank" uniqKey="Geller F" first="Frank" last="Geller">Frank Geller</name><affiliation><nlm:aff id="A46">Department of Epidemiology Research, Statens Serum Institut, Copenhagen DK-2300, Denmark.</nlm:aff></affiliation></author><author><name sortKey="Giedraitis, Vilmantas" sort="Giedraitis, Vilmantas" uniqKey="Giedraitis V" first="Vilmantas" last="Giedraitis">Vilmantas Giedraitis</name><affiliation><nlm:aff id="A110">Department of Public Health and Caring Sciences, Geriatrics, Uppsala University, Uppsala 75185, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Gigante, Bruna" sort="Gigante, Bruna" uniqKey="Gigante B" first="Bruna" last="Gigante">Bruna Gigante</name><affiliation><nlm:aff id="A111">Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, Stockholm 17177, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Go, Alan S" sort="Go, Alan S" uniqKey="Go A" first="Alan S." last="Go">Alan S. Go</name><affiliation><nlm:aff id="A112">Kaiser Permanente, Division of Research, Oakland, California 94612, USA.</nlm:aff></affiliation></author><author><name sortKey="Golay, Alain" sort="Golay, Alain" uniqKey="Golay A" first="Alain" last="Golay">Alain Golay</name><affiliation><nlm:aff id="A113">Service of Therapeutic Education for Diabetes, Obesity and Chronic Diseases, Geneva University Hospital, Geneva CH-1211, Switzerland.</nlm:aff></affiliation></author><author><name sortKey="Goodall, Alison H" sort="Goodall, Alison H" uniqKey="Goodall A" first="Alison H." last="Goodall">Alison H. Goodall</name><affiliation><nlm:aff id="A114">Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester LE3 9QP, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A115">National Institute for Health Research (NIHR) Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester LE3 9QP, UK.</nlm:aff></affiliation></author><author><name sortKey="Gordon, Scott D" sort="Gordon, Scott D" uniqKey="Gordon S" first="Scott D." last="Gordon">Scott D. Gordon</name><affiliation><nlm:aff id="A61">QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4006, Australia.</nlm:aff></affiliation></author><author><name sortKey="Gorski, Mathias" sort="Gorski, Mathias" uniqKey="Gorski M" first="Mathias" last="Gorski">Mathias Gorski</name><affiliation><nlm:aff id="A23">Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, D-93053 Regensburg, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A116">Department of Nephrology, University Hospital Regensburg, D-93053 Regensburg, Germany.</nlm:aff></affiliation></author><author><name sortKey="Grabe, Hans Jorgen" sort="Grabe, Hans Jorgen" uniqKey="Grabe H" first="Hans-Jörgen" last="Grabe">Hans-Jörgen Grabe</name><affiliation><nlm:aff id="A117">Department of Psychiatry and Psychotherapy, University Medicine Greifswald, HELIOS-Hospital Stralsund, D-17475 Greifswald, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A118">German Center for Neurodegenerative Diseases (DZNE), Rostock, Greifswald, D-17475 Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Grallert, Harald" sort="Grallert, Harald" uniqKey="Grallert H" first="Harald" last="Grallert">Harald Grallert</name><affiliation><nlm:aff id="A85">Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A119">Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A120">German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany.</nlm:aff></affiliation></author><author><name sortKey="Grammer, Tanja B" sort="Grammer, Tanja B" uniqKey="Grammer T" first="Tanja B." last="Grammer">Tanja B. Grammer</name><affiliation><nlm:aff id="A51">Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, D-68187 Mannheim, Germany.</nlm:aff></affiliation></author><author><name sortKey="Gr Ler, Jurgen" sort="Gr Ler, Jurgen" uniqKey="Gr Ler J" first="Jürgen" last="Gr Ler">Jürgen Gr Ler</name><affiliation><nlm:aff id="A121">Department of Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, D-01307 Dresden, Germany.</nlm:aff></affiliation></author><author><name sortKey="Gronberg, Henrik" sort="Gronberg, Henrik" uniqKey="Gronberg H" first="Henrik" last="Grönberg">Henrik Grönberg</name><affiliation><nlm:aff id="A15">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Groves, Christopher J" sort="Groves, Christopher J" uniqKey="Groves C" first="Christopher J." last="Groves">Christopher J. Groves</name><affiliation><nlm:aff id="A64">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.</nlm:aff></affiliation></author><author><name sortKey="Gusto, Gaelle" sort="Gusto, Gaelle" uniqKey="Gusto G" first="Gaëlle" last="Gusto">Gaëlle Gusto</name><affiliation><nlm:aff id="A122">Institut inter Régional pour la Santé, Synergies, F-37520 La Riche, France.</nlm:aff></affiliation></author><author><name sortKey="Haessler, Jeffrey" sort="Haessler, Jeffrey" uniqKey="Haessler J" first="Jeffrey" last="Haessler">Jeffrey Haessler</name><affiliation><nlm:aff id="A49">Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.</nlm:aff></affiliation></author><author><name sortKey="Hall, Per" sort="Hall, Per" uniqKey="Hall P" first="Per" last="Hall">Per Hall</name><affiliation><nlm:aff id="A15">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Haller, Toomas" sort="Haller, Toomas" uniqKey="Haller T" first="Toomas" last="Haller">Toomas Haller</name><affiliation><nlm:aff id="A14">Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.</nlm:aff></affiliation></author><author><name sortKey="Hallmans, Goran" sort="Hallmans, Goran" uniqKey="Hallmans G" first="Goran" last="Hallmans">Goran Hallmans</name><affiliation><nlm:aff id="A123">Department of Public Health and Clinical Medicine, Unit of Nutritional Research, Umeå University, Umeå 90187, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Hartman, Catharina A" sort="Hartman, Catharina A" uniqKey="Hartman C" first="Catharina A." last="Hartman">Catharina A. Hartman</name><affiliation><nlm:aff id="A124">Department of Psychiatry, University of Groningen, University Medical Center Groningen, 9700RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Hassinen, Maija" sort="Hassinen, Maija" uniqKey="Hassinen M" first="Maija" last="Hassinen">Maija Hassinen</name><affiliation><nlm:aff id="A125">Kuopio Research Institute of Exercise Medicine, 70100 Kuopio, Finland.</nlm:aff></affiliation></author><author><name sortKey="Hayward, Caroline" sort="Hayward, Caroline" uniqKey="Hayward C" first="Caroline" last="Hayward">Caroline Hayward</name><affiliation><nlm:aff id="A126">MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK.</nlm:aff></affiliation></author><author><name sortKey="Heard Costa, Nancy L" sort="Heard Costa, Nancy L" uniqKey="Heard Costa N" first="Nancy L." last="Heard-Costa">Nancy L. Heard-Costa</name><affiliation><nlm:aff id="A127">National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts 01702, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A128">Department of Neurology, Boston University School of Medicine, Boston, Massachusetts 02118, USA.</nlm:aff></affiliation></author><author><name sortKey="Helmer, Quinta" sort="Helmer, Quinta" uniqKey="Helmer Q" first="Quinta" last="Helmer">Quinta Helmer</name><affiliation><nlm:aff id="A34">Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A98">Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A129">Faculty of Psychology and Education, VU University Amsterdam, 1081BT Amsterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Hengstenberg, Christian" sort="Hengstenberg, Christian" uniqKey="Hengstenberg C" first="Christian" last="Hengstenberg">Christian Hengstenberg</name><affiliation><nlm:aff id="A130">Deutsches Forschungszentrum für Herz-Kreislauferkrankungen (DZHK) (German Research Centre for Cardiovascular Research), Munich Heart Alliance, D-80636 Munich, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A131">Deutsches Herzzentrum München, Technische Universität München, D-80636 Munich, Germany.</nlm:aff></affiliation></author><author><name sortKey="Holmen, Oddgeir" sort="Holmen, Oddgeir" uniqKey="Holmen O" first="Oddgeir" last="Holmen">Oddgeir Holmen</name><affiliation><nlm:aff id="A132">Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim 7489, Norway.</nlm:aff></affiliation></author><author><name sortKey="Hottenga, Jouke Jan" sort="Hottenga, Jouke Jan" uniqKey="Hottenga J" first="Jouke-Jan" last="Hottenga">Jouke-Jan Hottenga</name><affiliation><nlm:aff id="A133">Biological Psychology, VU University Amsterdam, 1081BT Amsterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="James, Alan L" sort="James, Alan L" uniqKey="James A" first="Alan L." last="James">Alan L. James</name><affiliation><nlm:aff id="A134">Department of Pulmonary Physiology and Sleep Medicine, Nedlands, Western Australia 6009, Australia.</nlm:aff></affiliation><affiliation><nlm:aff id="A135">School of Medicine and Pharmacology, University of Western Australia, Crawley 6009, Australia.</nlm:aff></affiliation></author><author><name sortKey="Jeff, Janina M" sort="Jeff, Janina M" uniqKey="Jeff J" first="Janina M." last="Jeff">Janina M. Jeff</name><affiliation><nlm:aff id="A55">The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:aff></affiliation></author><author><name sortKey="Johansson, Sa" sort="Johansson, Sa" uniqKey="Johansson " first=" Sa" last="Johansson"> Sa Johansson</name><affiliation><nlm:aff id="A136">Uppsala University, Department of Immunology, Genetics, Pathology, SciLifeLab, Rudbeck Laboratory, SE-751 85 Uppsala, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Jolley, Jennifer" sort="Jolley, Jennifer" uniqKey="Jolley J" first="Jennifer" last="Jolley">Jennifer Jolley</name><affiliation><nlm:aff id="A88">Department of Haematology, University of Cambridge, Cambridge CB2 0PT, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A89">NHS Blood and Transplant, Cambridge CB2 0PT, UK.</nlm:aff></affiliation></author><author><name sortKey="Juliusdottir, Thorhildur" sort="Juliusdottir, Thorhildur" uniqKey="Juliusdottir T" first="Thorhildur" last="Juliusdottir">Thorhildur Juliusdottir</name><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation></author><author><name sortKey="Kinnunen, Leena" sort="Kinnunen, Leena" uniqKey="Kinnunen L" first="Leena" last="Kinnunen">Leena Kinnunen</name><affiliation><nlm:aff id="A53">National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:aff></affiliation></author><author><name sortKey="Koenig, Wolfgang" sort="Koenig, Wolfgang" uniqKey="Koenig W" first="Wolfgang" last="Koenig">Wolfgang Koenig</name><affiliation><nlm:aff id="A52">Department of Internal Medicine II, Ulm University Medical Centre, D-89081 Ulm, Germany.</nlm:aff></affiliation></author><author><name sortKey="Koskenvuo, Markku" sort="Koskenvuo, Markku" uniqKey="Koskenvuo M" first="Markku" last="Koskenvuo">Markku Koskenvuo</name><affiliation><nlm:aff id="A137">Hjelt Institute Department of Public Health, University of Helsinki, FI-00014 Helsinki, Finland.</nlm:aff></affiliation></author><author><name sortKey="Kratzer, Wolfgang" sort="Kratzer, Wolfgang" uniqKey="Kratzer W" first="Wolfgang" last="Kratzer">Wolfgang Kratzer</name><affiliation><nlm:aff id="A138">Department of Internal Medicine I, Ulm University Medical Centre, D-89081 Ulm, Germany.</nlm:aff></affiliation></author><author><name sortKey="Laitinen, Jaana" sort="Laitinen, Jaana" uniqKey="Laitinen J" first="Jaana" last="Laitinen">Jaana Laitinen</name><affiliation><nlm:aff id="A139">Finnish Institute of Occupational Health, FI-90100 Oulu, Finland.</nlm:aff></affiliation></author><author><name sortKey="Lamina, Claudia" sort="Lamina, Claudia" uniqKey="Lamina C" first="Claudia" last="Lamina">Claudia Lamina</name><affiliation><nlm:aff id="A140">Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, 6020 Innsbruck, Austria.</nlm:aff></affiliation></author><author><name sortKey="Leander, Karin" sort="Leander, Karin" uniqKey="Leander K" first="Karin" last="Leander">Karin Leander</name><affiliation><nlm:aff id="A111">Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, Stockholm 17177, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Lee, Nanette R" sort="Lee, Nanette R" uniqKey="Lee N" first="Nanette R." last="Lee">Nanette R. Lee</name><affiliation><nlm:aff id="A91">USC-Office of Population Studies Foundation, Inc., University of San Carlos, Cebu City 6000, Philippines.</nlm:aff></affiliation></author><author><name sortKey="Lichtner, Peter" sort="Lichtner, Peter" uniqKey="Lichtner P" first="Peter" last="Lichtner">Peter Lichtner</name><affiliation><nlm:aff id="A141">Institute of Human Genetics, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.</nlm:aff></affiliation></author><author><name sortKey="Lind, Lars" sort="Lind, Lars" uniqKey="Lind L" first="Lars" last="Lind">Lars Lind</name><affiliation><nlm:aff id="A142">Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala 75185, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Lindstrom, Jaana" sort="Lindstrom, Jaana" uniqKey="Lindstrom J" first="Jaana" last="Lindström">Jaana Lindström</name><affiliation><nlm:aff id="A53">National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:aff></affiliation></author><author><name sortKey="Lo, Ken Sin" sort="Lo, Ken Sin" uniqKey="Lo K" first="Ken Sin" last="Lo">Ken Sin Lo</name><affiliation><nlm:aff id="A143">Montreal Heart Institute, Montreal, Quebec H1T 1C8, Canada.</nlm:aff></affiliation></author><author><name sortKey="Lobbens, Stephane" sort="Lobbens, Stephane" uniqKey="Lobbens S" first="Stéphane" last="Lobbens">Stéphane Lobbens</name><affiliation><nlm:aff id="A80">CNRS UMR 8199, F-59019 Lille, France.</nlm:aff></affiliation><affiliation><nlm:aff id="A81">European Genomic Institute for Diabetes, F-59000 Lille, France.</nlm:aff></affiliation><affiliation><nlm:aff id="A82">Université de Lille 2, F-59000 Lille, France.</nlm:aff></affiliation></author><author><name sortKey="Lorbeer, Roberto" sort="Lorbeer, Roberto" uniqKey="Lorbeer R" first="Roberto" last="Lorbeer">Roberto Lorbeer</name><affiliation><nlm:aff id="A144">Institute for Community Medicine, University Medicine Greifswald, D-17475 Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Lu, Yingchang" sort="Lu, Yingchang" uniqKey="Lu Y" first="Yingchang" last="Lu">Yingchang Lu</name><affiliation><nlm:aff id="A55">The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A145">The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:aff></affiliation></author><author><name sortKey="Mach, Francois" sort="Mach, Francois" uniqKey="Mach F" first="François" last="Mach">François Mach</name><affiliation><nlm:aff id="A45">Cardiology, Department of Specialties of Internal Medicine, Geneva University Hospital, Geneva 1211, Switzerland.</nlm:aff></affiliation></author><author><name sortKey="Magnusson, Patrik K E" sort="Magnusson, Patrik K E" uniqKey="Magnusson P" first="Patrik K. E." last="Magnusson">Patrik K. E. Magnusson</name><affiliation><nlm:aff id="A15">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Mahajan, Anubha" sort="Mahajan, Anubha" uniqKey="Mahajan A" first="Anubha" last="Mahajan">Anubha Mahajan</name><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation></author><author><name sortKey="Mcardle, Wendy L" sort="Mcardle, Wendy L" uniqKey="Mcardle W" first="Wendy L." last="Mcardle">Wendy L. Mcardle</name><affiliation><nlm:aff id="A146">School of Social and Community Medicine, University of Bristol, Bristol BS8 2BN, UK.</nlm:aff></affiliation></author><author><name sortKey="Mclachlan, Stela" sort="Mclachlan, Stela" uniqKey="Mclachlan S" first="Stela" last="Mclachlan">Stela Mclachlan</name><affiliation><nlm:aff id="A36">Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK.</nlm:aff></affiliation></author><author><name sortKey="Menni, Cristina" sort="Menni, Cristina" uniqKey="Menni C" first="Cristina" last="Menni">Cristina Menni</name><affiliation><nlm:aff id="A56">Department of Twin Research and Genetic Epidemiology, King’s College London, London SE1 7EH, UK.</nlm:aff></affiliation></author><author><name sortKey="Merger, Sigrun" sort="Merger, Sigrun" uniqKey="Merger S" first="Sigrun" last="Merger">Sigrun Merger</name><affiliation><nlm:aff id="A95">Division of Endocrinology, Diabetes and Metabolism, Ulm University Medical Centre, D-89081 Ulm, Germany.</nlm:aff></affiliation></author><author><name sortKey="Mihailov, Evelin" sort="Mihailov, Evelin" uniqKey="Mihailov E" first="Evelin" last="Mihailov">Evelin Mihailov</name><affiliation><nlm:aff id="A14">Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.</nlm:aff></affiliation><affiliation><nlm:aff id="A147">Institute of Molecular and Cell Biology, University of Tartu, Tartu 51010, Estonia.</nlm:aff></affiliation></author><author><name sortKey="Milani, Lili" sort="Milani, Lili" uniqKey="Milani L" first="Lili" last="Milani">Lili Milani</name><affiliation><nlm:aff id="A14">Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.</nlm:aff></affiliation></author><author><name sortKey="Moayyeri, Alireza" sort="Moayyeri, Alireza" uniqKey="Moayyeri A" first="Alireza" last="Moayyeri">Alireza Moayyeri</name><affiliation><nlm:aff id="A56">Department of Twin Research and Genetic Epidemiology, King’s College London, London SE1 7EH, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A148">Farr Institute of Health Informatics Research, University College London, London NW1 2DA, UK.</nlm:aff></affiliation></author><author><name sortKey="Monda, Keri L" sort="Monda, Keri L" uniqKey="Monda K" first="Keri L." last="Monda">Keri L. Monda</name><affiliation><nlm:aff id="A4">Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A149">The Center for Observational Research, Amgen, Inc., Thousand Oaks, California 91320, USA.</nlm:aff></affiliation></author><author><name sortKey="Morken, Mario A" sort="Morken, Mario A" uniqKey="Morken M" first="Mario A." last="Morken">Mario A. Morken</name><affiliation><nlm:aff id="A99">Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA.</nlm:aff></affiliation></author><author><name sortKey="Mulas, Antonella" sort="Mulas, Antonella" uniqKey="Mulas A" first="Antonella" last="Mulas">Antonella Mulas</name><affiliation><nlm:aff id="A150">Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche, Cagliari, Sardinia 09042, Italy.</nlm:aff></affiliation></author><author><name sortKey="Muller, Gabriele" sort="Muller, Gabriele" uniqKey="Muller G" first="Gabriele" last="Müller">Gabriele Müller</name><affiliation><nlm:aff id="A151">Center for Evidence-based Healthcare, University Hospital Carl Gustav Carus, Technische Universität Dresden, D-01307 Dresden, Germany.</nlm:aff></affiliation></author><author><name sortKey="Muller Nurasyid, Martina" sort="Muller Nurasyid, Martina" uniqKey="Muller Nurasyid M" first="Martina" last="Müller-Nurasyid">Martina Müller-Nurasyid</name><affiliation><nlm:aff id="A85">Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A130">Deutsches Forschungszentrum für Herz-Kreislauferkrankungen (DZHK) (German Research Centre for Cardiovascular Research), Munich Heart Alliance, D-80636 Munich, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A152">Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität, D-81377 Munich, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A153">Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, D-81377 Munich, Germany.</nlm:aff></affiliation></author><author><name sortKey="Musk, Arthur W" sort="Musk, Arthur W" uniqKey="Musk A" first="Arthur W." last="Musk">Arthur W. Musk</name><affiliation><nlm:aff id="A154">Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia 6009, Australia.</nlm:aff></affiliation></author><author><name sortKey="Nagaraja, Ramaiah" sort="Nagaraja, Ramaiah" uniqKey="Nagaraja R" first="Ramaiah" last="Nagaraja">Ramaiah Nagaraja</name><affiliation><nlm:aff id="A155">Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland 21224, USA.</nlm:aff></affiliation></author><author><name sortKey="Nothen, Markus M" sort="Nothen, Markus M" uniqKey="Nothen M" first="Markus M." last="Nöthen">Markus M. Nöthen</name><affiliation><nlm:aff id="A156">Department of Genomics, Life & Brain Center, University of Bonn, 53127 Bonn, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A157">Institute of Human Genetics, University of Bonn, 53127 Bonn, Germany.</nlm:aff></affiliation></author><author><name sortKey="Nolte, Ilja M" sort="Nolte, Ilja M" uniqKey="Nolte I" first="Ilja M." last="Nolte">Ilja M. Nolte</name><affiliation><nlm:aff id="A158">Department of Epidemiology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Pilz, Stefan" sort="Pilz, Stefan" uniqKey="Pilz S" first="Stefan" last="Pilz">Stefan Pilz</name><affiliation><nlm:aff id="A159">Department of Epidemiology and Biostatistics, Institute for Research in Extramural Medicine, Institute for Health and Care Research, VU University Medical Center, 1081BT Amsterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A160">Department of Internal Medicine, Division of Endocrinology and Metabolism, Medical University of Graz, 8036 Graz, Austria.</nlm:aff></affiliation></author><author><name sortKey="Rayner, Nigel W" sort="Rayner, Nigel W" uniqKey="Rayner N" first="Nigel W." last="Rayner">Nigel W. Rayner</name><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A22">Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A64">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.</nlm:aff></affiliation></author><author><name sortKey="Renstrom, Frida" sort="Renstrom, Frida" uniqKey="Renstrom F" first="Frida" last="Renstrom">Frida Renstrom</name><affiliation><nlm:aff id="A66">Department of Clinical Sciences, Genetic & Molecular Epidemiology Unit, Lund University Diabetes Center, Skåne University Hosptial, Malmö 205 02, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Rettig, Rainer" sort="Rettig, Rainer" uniqKey="Rettig R" first="Rainer" last="Rettig">Rainer Rettig</name><affiliation><nlm:aff id="A161">Institute of Physiology, University Medicine Greifswald, D-17495 Karlsburg, Germany.</nlm:aff></affiliation></author><author><name sortKey="Ried, Janina S" sort="Ried, Janina S" uniqKey="Ried J" first="Janina S." last="Ried">Janina S. Ried</name><affiliation><nlm:aff id="A85">Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.</nlm:aff></affiliation></author><author><name sortKey="Ripke, Stephan" sort="Ripke, Stephan" uniqKey="Ripke S" first="Stephan" last="Ripke">Stephan Ripke</name><affiliation><nlm:aff id="A108">Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A162">Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.</nlm:aff></affiliation></author><author><name sortKey="Robertson, Neil R" sort="Robertson, Neil R" uniqKey="Robertson N" first="Neil R." last="Robertson">Neil R. Robertson</name><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A64">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.</nlm:aff></affiliation></author><author><name sortKey="Rose, Lynda M" sort="Rose, Lynda M" uniqKey="Rose L" first="Lynda M." last="Rose">Lynda M. Rose</name><affiliation><nlm:aff id="A163">Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, Massachusetts 02215, USA.</nlm:aff></affiliation></author><author><name sortKey="Sanna, Serena" sort="Sanna, Serena" uniqKey="Sanna S" first="Serena" last="Sanna">Serena Sanna</name><affiliation><nlm:aff id="A150">Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche, Cagliari, Sardinia 09042, Italy.</nlm:aff></affiliation></author><author><name sortKey="Scharnagl, Hubert" sort="Scharnagl, Hubert" uniqKey="Scharnagl H" first="Hubert" last="Scharnagl">Hubert Scharnagl</name><affiliation><nlm:aff id="A164">Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz 8036, Austria.</nlm:aff></affiliation></author><author><name sortKey="Scholtens, Salome" sort="Scholtens, Salome" uniqKey="Scholtens S" first="Salome" last="Scholtens">Salome Scholtens</name><affiliation><nlm:aff id="A100">LifeLines Cohort Study, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Schumacher, Fredrick R" sort="Schumacher, Fredrick R" uniqKey="Schumacher F" first="Fredrick R." last="Schumacher">Fredrick R. Schumacher</name><affiliation><nlm:aff id="A165">Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA.</nlm:aff></affiliation></author><author><name sortKey="Scott, William R" sort="Scott, William R" uniqKey="Scott W" first="William R." last="Scott">William R. Scott</name><affiliation><nlm:aff id="A41">Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A83">Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.</nlm:aff></affiliation></author><author><name sortKey="Seufferlein, Thomas" sort="Seufferlein, Thomas" uniqKey="Seufferlein T" first="Thomas" last="Seufferlein">Thomas Seufferlein</name><affiliation><nlm:aff id="A138">Department of Internal Medicine I, Ulm University Medical Centre, D-89081 Ulm, Germany.</nlm:aff></affiliation></author><author><name sortKey="Shi, Jianxin" sort="Shi, Jianxin" uniqKey="Shi J" first="Jianxin" last="Shi">Jianxin Shi</name><affiliation><nlm:aff id="A166">National Cancer Institute, Bethesda, Maryland 20892, USA.</nlm:aff></affiliation></author><author><name sortKey="Smith, Albert Vernon" sort="Smith, Albert Vernon" uniqKey="Smith A" first="Albert Vernon" last="Smith">Albert Vernon Smith</name><affiliation><nlm:aff id="A167">Icelandic Heart Association, Kopavogur 201, Iceland.</nlm:aff></affiliation><affiliation><nlm:aff id="A168">University of Iceland, Reykjavik 101, Iceland.</nlm:aff></affiliation></author><author><name sortKey="Smolonska, Joanna" sort="Smolonska, Joanna" uniqKey="Smolonska J" first="Joanna" last="Smolonska">Joanna Smolonska</name><affiliation><nlm:aff id="A29">Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A169">Department of Epidemiology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Stanton, Alice V" sort="Stanton, Alice V" uniqKey="Stanton A" first="Alice V." last="Stanton">Alice V. Stanton</name><affiliation><nlm:aff id="A170">Molecular & Cellular Therapeutics, Royal College of Surgeons in Ireland, 123 St Stephen’s Green, Dublin 2, Ireland.</nlm:aff></affiliation></author><author><name sortKey="Steinthorsdottir, Valgerdur" sort="Steinthorsdottir, Valgerdur" uniqKey="Steinthorsdottir V" first="Valgerdur" last="Steinthorsdottir">Valgerdur Steinthorsdottir</name><affiliation><nlm:aff id="A171">deCODE Genetics, Amgen Inc., Reykjavik 101, Iceland.</nlm:aff></affiliation></author><author><name sortKey="Stirrups, Kathleen" sort="Stirrups, Kathleen" uniqKey="Stirrups K" first="Kathleen" last="Stirrups">Kathleen Stirrups</name><affiliation><nlm:aff id="A22">Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A50">William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.</nlm:aff></affiliation></author><author><name sortKey="Stringham, Heather M" sort="Stringham, Heather M" uniqKey="Stringham H" first="Heather M." last="Stringham">Heather M. Stringham</name><affiliation><nlm:aff id="A1">Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation></author><author><name sortKey="Sundstrom, Johan" sort="Sundstrom, Johan" uniqKey="Sundstrom J" first="Johan" last="Sundström">Johan Sundström</name><affiliation><nlm:aff id="A142">Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala 75185, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Swertz, Morris A" sort="Swertz, Morris A" uniqKey="Swertz M" first="Morris A." last="Swertz">Morris A. Swertz</name><affiliation><nlm:aff id="A29">Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Swift, Amy J" sort="Swift, Amy J" uniqKey="Swift A" first="Amy J." last="Swift">Amy J. Swift</name><affiliation><nlm:aff id="A99">Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA.</nlm:aff></affiliation></author><author><name sortKey="Syv Nen, Ann Christine" sort="Syv Nen, Ann Christine" uniqKey="Syv Nen A" first="Ann-Christine" last="Syv Nen">Ann-Christine Syv Nen</name><affiliation><nlm:aff id="A16">Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.</nlm:aff></affiliation><affiliation><nlm:aff id="A172">Department of Medical Sciences, Molecular Medicine, Uppsala University, Uppsala 75144, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Tan, Sian Tsung" sort="Tan, Sian Tsung" uniqKey="Tan S" first="Sian-Tsung" last="Tan">Sian-Tsung Tan</name><affiliation><nlm:aff id="A41">Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A173">National Heart and Lung Institute, Imperial College London, London SW3 6LY, UK.</nlm:aff></affiliation></author><author><name sortKey="Tayo, Bamidele O" sort="Tayo, Bamidele O" uniqKey="Tayo B" first="Bamidele O." last="Tayo">Bamidele O. Tayo</name><affiliation><nlm:aff id="A174">Department of Public Health Sciences, Stritch School of Medicine, Loyola University of Chicago, Maywood, Illinois 61053, USA.</nlm:aff></affiliation></author><author><name sortKey="Thorand, Barbara" sort="Thorand, Barbara" uniqKey="Thorand B" first="Barbara" last="Thorand">Barbara Thorand</name><affiliation><nlm:aff id="A120">German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A175">Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany, D-85764 Neuherberg, Germany.</nlm:aff></affiliation></author><author><name sortKey="Thorleifsson, Gudmar" sort="Thorleifsson, Gudmar" uniqKey="Thorleifsson G" first="Gudmar" last="Thorleifsson">Gudmar Thorleifsson</name><affiliation><nlm:aff id="A171">deCODE Genetics, Amgen Inc., Reykjavik 101, Iceland.</nlm:aff></affiliation></author><author><name sortKey="Tyrer, Jonathan P" sort="Tyrer, Jonathan P" uniqKey="Tyrer J" first="Jonathan P." last="Tyrer">Jonathan P. Tyrer</name><affiliation><nlm:aff id="A176">Department of Oncology, University of Cambridge, Cambridge CB2 0QQ, UK.</nlm:aff></affiliation></author><author><name sortKey="Uh, Hae Won" sort="Uh, Hae Won" uniqKey="Uh H" first="Hae-Won" last="Uh">Hae-Won Uh</name><affiliation><nlm:aff id="A34">Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A98">Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Vandenput, Liesbeth" sort="Vandenput, Liesbeth" uniqKey="Vandenput L" first="Liesbeth" last="Vandenput">Liesbeth Vandenput</name><affiliation><nlm:aff id="A177">Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg 413 45, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Verhulst, Frank C" sort="Verhulst, Frank C" uniqKey="Verhulst F" first="Frank C." last="Verhulst">Frank C. Verhulst</name><affiliation><nlm:aff id="A178">Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC University Medical Centre, 3000 CB Rotterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Vermeulen, Sita H" sort="Vermeulen, Sita H" uniqKey="Vermeulen S" first="Sita H." last="Vermeulen">Sita H. Vermeulen</name><affiliation><nlm:aff id="A179">Department for Health Evidence, Radboud University Medical Centre, 6500 HB Nijmegen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A180">Department of Genetics, Radboud University Medical Centre, 6500 HB Nijmegen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Verweij, Niek" sort="Verweij, Niek" uniqKey="Verweij N" first="Niek" last="Verweij">Niek Verweij</name><affiliation><nlm:aff id="A57">Department of Cardiology, University Medical Center Groningen, University of Groningen, 9700RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Vonk, Judith M" sort="Vonk, Judith M" uniqKey="Vonk J" first="Judith M." last="Vonk">Judith M. Vonk</name><affiliation><nlm:aff id="A169">Department of Epidemiology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Waite, Lindsay L" sort="Waite, Lindsay L" uniqKey="Waite L" first="Lindsay L." last="Waite">Lindsay L. Waite</name><affiliation><nlm:aff id="A31">HudsonAlpha Institute for Biotechnology, Huntsville, Alabama 35806, USA.</nlm:aff></affiliation></author><author><name sortKey="Warren, Helen R" sort="Warren, Helen R" uniqKey="Warren H" first="Helen R." last="Warren">Helen R. Warren</name><affiliation><nlm:aff id="A181">Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.</nlm:aff></affiliation></author><author><name sortKey="Waterworth, Dawn" sort="Waterworth, Dawn" uniqKey="Waterworth D" first="Dawn" last="Waterworth">Dawn Waterworth</name><affiliation><nlm:aff id="A182">Genetics, GlaxoSmithKline, King of Prussia, Pennsylvania 19406, USA.</nlm:aff></affiliation></author><author><name sortKey="Weedon, Michael N" sort="Weedon, Michael N" uniqKey="Weedon M" first="Michael N." last="Weedon">Michael N. Weedon</name><affiliation><nlm:aff id="A24">Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK.</nlm:aff></affiliation></author><author><name sortKey="Wilkens, Lynne R" sort="Wilkens, Lynne R" uniqKey="Wilkens L" first="Lynne R." last="Wilkens">Lynne R. Wilkens</name><affiliation><nlm:aff id="A54">Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96813, USA.</nlm:aff></affiliation></author><author><name sortKey="Willenborg, Christina" sort="Willenborg, Christina" uniqKey="Willenborg C" first="Christina" last="Willenborg">Christina Willenborg</name><affiliation><nlm:aff id="A183">German Center for Cardiovascular Research, partner site Hamburg/Lubeck/Kiel, 23562 Lubeck, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A184">Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, D-23562 Lübeck, Germany.</nlm:aff></affiliation></author><author><name sortKey="Wilsgaard, Tom" sort="Wilsgaard, Tom" uniqKey="Wilsgaard T" first="Tom" last="Wilsgaard">Tom Wilsgaard</name><affiliation><nlm:aff id="A185">Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, 9037 Tromsø, Norway.</nlm:aff></affiliation></author><author><name sortKey="Wojczynski, Mary K" sort="Wojczynski, Mary K" uniqKey="Wojczynski M" first="Mary K." last="Wojczynski">Mary K. Wojczynski</name><affiliation><nlm:aff id="A47">Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:aff></affiliation></author><author><name sortKey="Wong, Andrew" sort="Wong, Andrew" uniqKey="Wong A" first="Andrew" last="Wong">Andrew Wong</name><affiliation><nlm:aff id="A186">MRC Unit for Lifelong Health and Ageing at University College London, London WC1B 5JU, UK.</nlm:aff></affiliation></author><author><name sortKey="Wright, Alan F" sort="Wright, Alan F" uniqKey="Wright A" first="Alan F." last="Wright">Alan F. Wright</name><affiliation><nlm:aff id="A126">MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK.</nlm:aff></affiliation></author><author><name sortKey="Zhang, Qunyuan" sort="Zhang, Qunyuan" uniqKey="Zhang Q" first="Qunyuan" last="Zhang">Qunyuan Zhang</name><affiliation><nlm:aff id="A47">Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:aff></affiliation></author><author><name sortKey="Brennan, Eoin P" sort="Brennan, Eoin P" uniqKey="Brennan E" first="Eoin P." last="Brennan">Eoin P. Brennan</name><affiliation><nlm:aff id="A187">Diabetes Complications Research Centre, Conway Institute, School of Medicine and Medical Sciences, University College Dublin, Dublin 4, Ireland.</nlm:aff></affiliation></author><author><name sortKey="Choi, Murim" sort="Choi, Murim" uniqKey="Choi M" first="Murim" last="Choi">Murim Choi</name><affiliation><nlm:aff id="A188">Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea.</nlm:aff></affiliation></author><author><name sortKey="Dastani, Zari" sort="Dastani, Zari" uniqKey="Dastani Z" first="Zari" last="Dastani">Zari Dastani</name><affiliation><nlm:aff id="A189">Lady Davis Institute, Departments of Human Genetics, Epidemiology and Biostatistics, McGill University, Montréal, Québec H3T1E2, Canada.</nlm:aff></affiliation></author><author><name sortKey="Drong, Alexander W" sort="Drong, Alexander W" uniqKey="Drong A" first="Alexander W." last="Drong">Alexander W. Drong</name><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation></author><author><name sortKey="Eriksson, Per" sort="Eriksson, Per" uniqKey="Eriksson P" first="Per" last="Eriksson">Per Eriksson</name><affiliation><nlm:aff id="A70">Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm 17176, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Franco Cereceda, Anders" sort="Franco Cereceda, Anders" uniqKey="Franco Cereceda A" first="Anders" last="Franco-Cereceda">Anders Franco-Cereceda</name><affiliation><nlm:aff id="A190">Cardiothoracic Surgery Unit, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm 17176, Sweden.</nlm:aff></affiliation></author><author><name sortKey="G Din, Jesper R" sort="G Din, Jesper R" uniqKey="G Din J" first="Jesper R." last="G Din">Jesper R. G Din</name><affiliation><nlm:aff id="A70">Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm 17176, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Gharavi, Ali G" sort="Gharavi, Ali G" uniqKey="Gharavi A" first="Ali G." last="Gharavi">Ali G. Gharavi</name><affiliation><nlm:aff id="A191">Department of Medicine, Columbia University College of Physicians and Surgeons, New York 10032, USA.</nlm:aff></affiliation></author><author><name sortKey="Goddard, Michael E" sort="Goddard, Michael E" uniqKey="Goddard M" first="Michael E." last="Goddard">Michael E. Goddard</name><affiliation><nlm:aff id="A192">Biosciences Research Division, Department of Primary Industries, Victoria 3083, Australia.</nlm:aff></affiliation><affiliation><nlm:aff id="A193">Department of Food and Agricultural Systems, University of Melbourne, Victoria 3010, Australia.</nlm:aff></affiliation></author><author><name sortKey="Handsaker, Robert E" sort="Handsaker, Robert E" uniqKey="Handsaker R" first="Robert E." last="Handsaker">Robert E. Handsaker</name><affiliation><nlm:aff id="A6">Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A7">Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation></author><author><name sortKey="Huang, Jinyan" sort="Huang, Jinyan" uniqKey="Huang J" first="Jinyan" last="Huang">Jinyan Huang</name><affiliation><nlm:aff id="A194">Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A195">State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Rui Jin Hospital Affiliated with Shanghai Jiao Tong University School of Medicine, Shanghai, China.</nlm:aff></affiliation></author><author><name sortKey="Karpe, Fredrik" sort="Karpe, Fredrik" uniqKey="Karpe F" first="Fredrik" last="Karpe">Fredrik Karpe</name><affiliation><nlm:aff id="A64">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A196">NIHR Oxford Biomedical Research Centre, OUH Trust, Oxford OX3 7LE, UK.</nlm:aff></affiliation></author><author><name sortKey="Kathiresan, Sekar" sort="Kathiresan, Sekar" uniqKey="Kathiresan S" first="Sekar" last="Kathiresan">Sekar Kathiresan</name><affiliation><nlm:aff id="A6">Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A197">Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.</nlm:aff></affiliation></author><author><name sortKey="Keildson, Sarah" sort="Keildson, Sarah" uniqKey="Keildson S" first="Sarah" last="Keildson">Sarah Keildson</name><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation></author><author><name sortKey="Kiryluk, Krzysztof" sort="Kiryluk, Krzysztof" uniqKey="Kiryluk K" first="Krzysztof" last="Kiryluk">Krzysztof Kiryluk</name><affiliation><nlm:aff id="A191">Department of Medicine, Columbia University College of Physicians and Surgeons, New York 10032, USA.</nlm:aff></affiliation></author><author><name sortKey="Kubo, Michiaki" sort="Kubo, Michiaki" uniqKey="Kubo M" first="Michiaki" last="Kubo">Michiaki Kubo</name><affiliation><nlm:aff id="A198">Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Yokohama 230-0045, Japan.</nlm:aff></affiliation></author><author><name sortKey="Lee, Jong Young" sort="Lee, Jong Young" uniqKey="Lee J" first="Jong-Young" last="Lee">Jong-Young Lee</name><affiliation><nlm:aff id="A199">Center for Genome Science, National Institute of Health, Chungcheongbuk-do, Chungbuk 363–951, Republic of Korea.</nlm:aff></affiliation></author><author><name sortKey="Liang, Liming" sort="Liang, Liming" uniqKey="Liang L" first="Liming" last="Liang">Liming Liang</name><affiliation><nlm:aff id="A194">Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A200">Harvard School of Public Health, Department of Biostatistics, Harvard University, Boston, Massachusetts 2115, USA.</nlm:aff></affiliation></author><author><name sortKey="Lifton, Richard P" sort="Lifton, Richard P" uniqKey="Lifton R" first="Richard P." last="Lifton">Richard P. Lifton</name><affiliation><nlm:aff id="A201">Department of Genetics, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, New Haven, Connecticut 06520, USA.</nlm:aff></affiliation></author><author><name sortKey="Ma, Baoshan" sort="Ma, Baoshan" uniqKey="Ma B" first="Baoshan" last="Ma">Baoshan Ma</name><affiliation><nlm:aff id="A194">Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A202">College of Information Science and Technology, Dalian Maritime University, Dalian, Liaoning 116026, China.</nlm:aff></affiliation></author><author><name sortKey="Mccarroll, Steven A" sort="Mccarroll, Steven A" uniqKey="Mccarroll S" first="Steven A." last="Mccarroll">Steven A. Mccarroll</name><affiliation><nlm:aff id="A6">Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A7">Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A162">Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.</nlm:aff></affiliation></author><author><name sortKey="Mcknight, Amy J" sort="Mcknight, Amy J" uniqKey="Mcknight A" first="Amy J." last="Mcknight">Amy J. Mcknight</name><affiliation><nlm:aff id="A203">Nephrology Research, Centre for Public Health, Queen’s University of Belfast, Belfast, County Down BT9 7AB, UK.</nlm:aff></affiliation></author><author><name sortKey="Min, Josine L" sort="Min, Josine L" uniqKey="Min J" first="Josine L." last="Min">Josine L. Min</name><affiliation><nlm:aff id="A146">School of Social and Community Medicine, University of Bristol, Bristol BS8 2BN, UK.</nlm:aff></affiliation></author><author><name sortKey="Moffatt, Miriam F" sort="Moffatt, Miriam F" uniqKey="Moffatt M" first="Miriam F." last="Moffatt">Miriam F. Moffatt</name><affiliation><nlm:aff id="A173">National Heart and Lung Institute, Imperial College London, London SW3 6LY, UK.</nlm:aff></affiliation></author><author><name sortKey="Montgomery, Grant W" sort="Montgomery, Grant W" uniqKey="Montgomery G" first="Grant W." last="Montgomery">Grant W. Montgomery</name><affiliation><nlm:aff id="A61">QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4006, Australia.</nlm:aff></affiliation></author><author><name sortKey="Murabito, Joanne M" sort="Murabito, Joanne M" uniqKey="Murabito J" first="Joanne M." last="Murabito">Joanne M. Murabito</name><affiliation><nlm:aff id="A127">National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts 01702, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A204">Section of General Internal Medicine, Boston University School of Medicine, Boston, Massachusetts 02118, USA.</nlm:aff></affiliation></author><author><name sortKey="Nicholson, George" sort="Nicholson, George" uniqKey="Nicholson G" first="George" last="Nicholson">George Nicholson</name><affiliation><nlm:aff id="A205">Department of Statistics, University of Oxford, 1 South Parks Road, Oxford OX1 3TG, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A206">MRC Harwell, Harwell Science and Innovation Campus, Harwell OX11 0QG, UK.</nlm:aff></affiliation></author><author><name sortKey="Nyholt, Dale R" sort="Nyholt, Dale R" uniqKey="Nyholt D" first="Dale R." last="Nyholt">Dale R. Nyholt</name><affiliation><nlm:aff id="A61">QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4006, Australia.</nlm:aff></affiliation><affiliation><nlm:aff id="A207">Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland 4059, Australia.</nlm:aff></affiliation></author><author><name sortKey="Okada, Yukinori" sort="Okada, Yukinori" uniqKey="Okada Y" first="Yukinori" last="Okada">Yukinori Okada</name><affiliation><nlm:aff id="A208">Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama 230-0045, Japan.</nlm:aff></affiliation><affiliation><nlm:aff id="A209">Department of Human Genetics and Disease Diversity, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 113-8510 Tokyo, Japan.</nlm:aff></affiliation></author><author><name sortKey="Perry, John R B" sort="Perry, John R B" uniqKey="Perry J" first="John R. B." last="Perry">John R. B. Perry</name><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A24">Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A56">Department of Twin Research and Genetic Epidemiology, King’s College London, London SE1 7EH, UK.</nlm:aff></affiliation></author><author><name sortKey="Dorajoo, Rajkumar" sort="Dorajoo, Rajkumar" uniqKey="Dorajoo R" first="Rajkumar" last="Dorajoo">Rajkumar Dorajoo</name><affiliation><nlm:aff id="A210">Genome Institute of Singapore, Agency for Science, Technology and Research, 138672 Singapore.</nlm:aff></affiliation></author><author><name sortKey="Reinmaa, Eva" sort="Reinmaa, Eva" uniqKey="Reinmaa E" first="Eva" last="Reinmaa">Eva Reinmaa</name><affiliation><nlm:aff id="A14">Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.</nlm:aff></affiliation></author><author><name sortKey="Salem, Rany M" sort="Salem, Rany M" uniqKey="Salem R" first="Rany M." last="Salem">Rany M. Salem</name><affiliation><nlm:aff id="A5">Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children’s Hospital, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A6">Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A7">Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation></author><author><name sortKey="Sandholm, Niina" sort="Sandholm, Niina" uniqKey="Sandholm N" first="Niina" last="Sandholm">Niina Sandholm</name><affiliation><nlm:aff id="A211">Department of Biomedical Engineering and Computational Science, Aalto University School of Science, Helsinki FI-00076, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A212">Department of Medicine, Division of Nephrology, Helsinki University Central Hospital, FI-00290 Helsinki, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A213">Folkhälsan Institute of Genetics, Folkhälsan Research Center, FI-00290 Helsinki, Finland.</nlm:aff></affiliation></author><author><name sortKey="Scott, Robert A" sort="Scott, Robert A" uniqKey="Scott R" first="Robert A." last="Scott">Robert A. Scott</name><affiliation><nlm:aff id="A9">MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:aff></affiliation></author><author><name sortKey="Stolk, Lisette" sort="Stolk, Lisette" uniqKey="Stolk L" first="Lisette" last="Stolk">Lisette Stolk</name><affiliation><nlm:aff id="A34">Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A60">Department of Internal Medicine, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Takahashi, Atsushi" sort="Takahashi, Atsushi" uniqKey="Takahashi A" first="Atsushi" last="Takahashi">Atsushi Takahashi</name><affiliation><nlm:aff id="A208">Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama 230-0045, Japan.</nlm:aff></affiliation></author><author><name sortKey="Tanaka, Toshihiro" sort="Tanaka, Toshihiro" uniqKey="Tanaka T" first="Toshihiro" last="Tanaka">Toshihiro Tanaka</name><affiliation><nlm:aff id="A209">Department of Human Genetics and Disease Diversity, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 113-8510 Tokyo, Japan.</nlm:aff></affiliation><affiliation><nlm:aff id="A214">Laboratory for Cardiovascular Diseases, RIKEN Center for Integrative Medical Sciences, Yokohama 230-0045, Japan.</nlm:aff></affiliation><affiliation><nlm:aff id="A215">Division of Disease Diversity, Bioresource Research Center, Tokyo Medical and Dental University, 113-8510 Tokyo, Japan.</nlm:aff></affiliation></author><author><name sortKey="Van Hooft, Ferdinand M" sort="Van Hooft, Ferdinand M" uniqKey="Van Hooft F" first="Ferdinand M." last="Van Hooft">Ferdinand M. Van Hooft</name><affiliation><nlm:aff id="A70">Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm 17176, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Vinkhuyzen, Anna A E" sort="Vinkhuyzen, Anna A E" uniqKey="Vinkhuyzen A" first="Anna A. E." last="Vinkhuyzen">Anna A. E. Vinkhuyzen</name><affiliation><nlm:aff id="A11">Queensland Brain Institute, The University of Queensland, Brisbane 4072, Australia.</nlm:aff></affiliation></author><author><name sortKey="Westra, Harm Jan" sort="Westra, Harm Jan" uniqKey="Westra H" first="Harm-Jan" last="Westra">Harm-Jan Westra</name><affiliation><nlm:aff id="A29">Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Zheng, Wei" sort="Zheng, Wei" uniqKey="Zheng W" first="Wei" last="Zheng">Wei Zheng</name><affiliation><nlm:aff id="A216">Division of Epidemiology, Department of Medicine; Vanderbilt Epidemiology Center; and Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee 37075, USA.</nlm:aff></affiliation></author><author><name sortKey="Zondervan, Krina T" sort="Zondervan, Krina T" uniqKey="Zondervan K" first="Krina T." last="Zondervan">Krina T. Zondervan</name><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A217">Nuffield Department of Obstetrics & Gynaecology, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation></author><author><name sortKey="Heath, Andrew C" sort="Heath, Andrew C" uniqKey="Heath A" first="Andrew C." last="Heath">Andrew C. Heath</name><affiliation><nlm:aff id="A218">Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:aff></affiliation></author><author><name sortKey="Arveiler, Dominique" sort="Arveiler, Dominique" uniqKey="Arveiler D" first="Dominique" last="Arveiler">Dominique Arveiler</name><affiliation><nlm:aff id="A219">Department of Epidemiology and Public Health, EA3430, University of Strasbourg, Faculty of Medicine, Strasbourg, France.</nlm:aff></affiliation></author><author><name sortKey="Bakker, Stephan J L" sort="Bakker, Stephan J L" uniqKey="Bakker S" first="Stephan J. L." last="Bakker">Stephan J. L. Bakker</name><affiliation><nlm:aff id="A220">Department of Internal Medicine, University Medical Center Groningen, University of Groningen, 9700RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Beilby, John" sort="Beilby, John" uniqKey="Beilby J" first="John" last="Beilby">John Beilby</name><affiliation><nlm:aff id="A87">PathWest Laboratory Medicine of Western Australia, Nedlands, Western Australia 6009, Australia.</nlm:aff></affiliation><affiliation><nlm:aff id="A221">Pathology and Laboratory Medicine, The University of Western Australia, Perth, Western Australia 6009, Australia.</nlm:aff></affiliation></author><author><name sortKey="Bergman, Richard N" sort="Bergman, Richard N" uniqKey="Bergman R" first="Richard N." last="Bergman">Richard N. Bergman</name><affiliation><nlm:aff id="A222">Cedars-Sinai Diabetes and Obesity Research Institute, Los Angeles, California 90048, USA.</nlm:aff></affiliation></author><author><name sortKey="Blangero, John" sort="Blangero, John" uniqKey="Blangero J" first="John" last="Blangero">John Blangero</name><affiliation><nlm:aff id="A92">Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas 78227, USA.</nlm:aff></affiliation></author><author><name sortKey="Bovet, Pascal" sort="Bovet, Pascal" uniqKey="Bovet P" first="Pascal" last="Bovet">Pascal Bovet</name><affiliation><nlm:aff id="A223">Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois and University of Lausanne, 1010 Lausanne, Switzerland.</nlm:aff></affiliation><affiliation><nlm:aff id="A224">Ministry of Health, Victoria, Republic of Seychelles.</nlm:aff></affiliation></author><author><name sortKey="Campbell, Harry" sort="Campbell, Harry" uniqKey="Campbell H" first="Harry" last="Campbell">Harry Campbell</name><affiliation><nlm:aff id="A36">Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK.</nlm:aff></affiliation></author><author><name sortKey="Caulfield, Mark J" sort="Caulfield, Mark J" uniqKey="Caulfield M" first="Mark J." last="Caulfield">Mark J. Caulfield</name><affiliation><nlm:aff id="A181">Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.</nlm:aff></affiliation></author><author><name sortKey="Cesana, Giancarlo" sort="Cesana, Giancarlo" uniqKey="Cesana G" first="Giancarlo" last="Cesana">Giancarlo Cesana</name><affiliation><nlm:aff id="A225">University of Milano, Bicocca, 20126, Italy.</nlm:aff></affiliation></author><author><name sortKey="Chakravarti, Aravinda" sort="Chakravarti, Aravinda" uniqKey="Chakravarti A" first="Aravinda" last="Chakravarti">Aravinda Chakravarti</name><affiliation><nlm:aff id="A44">Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.</nlm:aff></affiliation></author><author><name sortKey="Chasman, Daniel I" sort="Chasman, Daniel I" uniqKey="Chasman D" first="Daniel I." last="Chasman">Daniel I. Chasman</name><affiliation><nlm:aff id="A163">Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, Massachusetts 02215, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A226">Harvard Medical School, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation></author><author><name sortKey="Chines, Peter S" sort="Chines, Peter S" uniqKey="Chines P" first="Peter S." last="Chines">Peter S. Chines</name><affiliation><nlm:aff id="A99">Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA.</nlm:aff></affiliation></author><author><name sortKey="Collins, Francis S" sort="Collins, Francis S" uniqKey="Collins F" first="Francis S." last="Collins">Francis S. Collins</name><affiliation><nlm:aff id="A99">Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA.</nlm:aff></affiliation></author><author><name sortKey="Crawford, Dana C" sort="Crawford, Dana C" uniqKey="Crawford D" first="Dana C." last="Crawford">Dana C. Crawford</name><affiliation><nlm:aff id="A227">Center for Human Genetics Research, Vanderbilt University Medical Center, Nashville, Tennessee 37203, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A228">Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee 37232, USA.</nlm:aff></affiliation></author><author><name sortKey="Cupples, L Adrienne" sort="Cupples, L Adrienne" uniqKey="Cupples L" first="L. Adrienne" last="Cupples">L. Adrienne Cupples</name><affiliation><nlm:aff id="A127">National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts 01702, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A229">Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA.</nlm:aff></affiliation></author><author><name sortKey="Cusi, Daniele" sort="Cusi, Daniele" uniqKey="Cusi D" first="Daniele" last="Cusi">Daniele Cusi</name><affiliation><nlm:aff id="A230">Department of Health Sciences, University of Milano, I 20142, Italy.</nlm:aff></affiliation><affiliation><nlm:aff id="A231">Fondazione Filarete, Milano I 20139, Italy.</nlm:aff></affiliation></author><author><name sortKey="Danesh, John" sort="Danesh, John" uniqKey="Danesh J" first="John" last="Danesh">John Danesh</name><affiliation><nlm:aff id="A232">Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK.</nlm:aff></affiliation></author><author><name sortKey="De Faire, Ulf" sort="De Faire, Ulf" uniqKey="De Faire U" first="Ulf" last="De Faire">Ulf De Faire</name><affiliation><nlm:aff id="A111">Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, Stockholm 17177, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Den Ruijter, Hester M" sort="Den Ruijter, Hester M" uniqKey="Den Ruijter H" first="Hester M." last="Den Ruijter">Hester M. Den Ruijter</name><affiliation><nlm:aff id="A76">Experimental Cardiology Laboratory, Division Heart and Lungs, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A233">Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Dominiczak, Anna F" sort="Dominiczak, Anna F" uniqKey="Dominiczak A" first="Anna F." last="Dominiczak">Anna F. Dominiczak</name><affiliation><nlm:aff id="A234">Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK.</nlm:aff></affiliation></author><author><name sortKey="Erbel, Raimund" sort="Erbel, Raimund" uniqKey="Erbel R" first="Raimund" last="Erbel">Raimund Erbel</name><affiliation><nlm:aff id="A235">Clinic of Cardiology, West-German Heart Centre, University Hospital Essen, 45147 Essen, Germany.</nlm:aff></affiliation></author><author><name sortKey="Erdmann, Jeanette" sort="Erdmann, Jeanette" uniqKey="Erdmann J" first="Jeanette" last="Erdmann">Jeanette Erdmann</name><affiliation><nlm:aff id="A183">German Center for Cardiovascular Research, partner site Hamburg/Lubeck/Kiel, 23562 Lubeck, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A184">Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, D-23562 Lübeck, Germany.</nlm:aff></affiliation></author><author><name sortKey="Eriksson, Johan G" sort="Eriksson, Johan G" uniqKey="Eriksson J" first="Johan G." last="Eriksson">Johan G. Eriksson</name><affiliation><nlm:aff id="A53">National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A236">Department of General Practice and Primary Health Care, University of Helsinki, FI-00290 Helsinki, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A237">Unit of General Practice, Helsinki University Central Hospital, Helsinki 00290, Finland.</nlm:aff></affiliation></author><author><name sortKey="Farrall, Martin" sort="Farrall, Martin" uniqKey="Farrall M" first="Martin" last="Farrall">Martin Farrall</name><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A48">Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, UK.</nlm:aff></affiliation></author><author><name sortKey="Felix, Stephan B" sort="Felix, Stephan B" uniqKey="Felix S" first="Stephan B." last="Felix">Stephan B. Felix</name><affiliation><nlm:aff id="A238">Department of Internal Medicine B, University Medicine Greifswald, D-17475 Greifswald, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A239">DZHK (Deutsches Zentrum für Herz-Kreislaufforschung – German Centre for Cardiovascular Research), partner site Greifswald, D-17475 Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Ferrannini, Ele" sort="Ferrannini, Ele" uniqKey="Ferrannini E" first="Ele" last="Ferrannini">Ele Ferrannini</name><affiliation><nlm:aff id="A240">Department of Internal Medicine, University of Pisa, 56100 Pisa, Italy.</nlm:aff></affiliation><affiliation><nlm:aff id="A241">National Research Council Institute of Clinical Physiology, University of Pisa, 56124 Pisa, Italy.</nlm:aff></affiliation></author><author><name sortKey="Ferrieres, Jean" sort="Ferrieres, Jean" uniqKey="Ferrieres J" first="Jean" last="Ferrières">Jean Ferrières</name><affiliation><nlm:aff id="A242">Department of Cardiology, Toulouse University School of Medicine, Rangueil Hospital, 31400 Toulouse, France.</nlm:aff></affiliation></author><author><name sortKey="Ford, Ian" sort="Ford, Ian" uniqKey="Ford I" first="Ian" last="Ford">Ian Ford</name><affiliation><nlm:aff id="A243">Robertson Center for Biostatistics, University of Glasgow, Glasgow G12 8QQ, UK.</nlm:aff></affiliation></author><author><name sortKey="Forouhi, Nita G" sort="Forouhi, Nita G" uniqKey="Forouhi N" first="Nita G." last="Forouhi">Nita G. Forouhi</name><affiliation><nlm:aff id="A9">MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:aff></affiliation></author><author><name sortKey="Forrester, Terrence" sort="Forrester, Terrence" uniqKey="Forrester T" first="Terrence" last="Forrester">Terrence Forrester</name><affiliation><nlm:aff id="A244">UWI Solutions for Developing Countries, The University of the West Indies, Mona, Kingston 7, Jamaica.</nlm:aff></affiliation></author><author><name sortKey="Franco, Oscar H" sort="Franco, Oscar H" uniqKey="Franco O" first="Oscar H." last="Franco">Oscar H. Franco</name><affiliation><nlm:aff id="A58">Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A59">Department of Epidemiology, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Gansevoort, Ron T" sort="Gansevoort, Ron T" uniqKey="Gansevoort R" first="Ron T." last="Gansevoort">Ron T. Gansevoort</name><affiliation><nlm:aff id="A220">Department of Internal Medicine, University Medical Center Groningen, University of Groningen, 9700RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Gejman, Pablo V" sort="Gejman, Pablo V" uniqKey="Gejman P" first="Pablo V." last="Gejman">Pablo V. Gejman</name><affiliation><nlm:aff id="A245">NorthShore University HealthSystem, Evanston, IL 60201, University of Chicago, Chicago, Illinois, USA.</nlm:aff></affiliation></author><author><name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name><affiliation><nlm:aff id="A85">Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.</nlm:aff></affiliation></author><author><name sortKey="Gottesman, Omri" sort="Gottesman, Omri" uniqKey="Gottesman O" first="Omri" last="Gottesman">Omri Gottesman</name><affiliation><nlm:aff id="A55">The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:aff></affiliation></author><author><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name><affiliation><nlm:aff id="A167">Icelandic Heart Association, Kopavogur 201, Iceland.</nlm:aff></affiliation><affiliation><nlm:aff id="A168">University of Iceland, Reykjavik 101, Iceland.</nlm:aff></affiliation></author><author><name sortKey="Gyllensten, Ulf" sort="Gyllensten, Ulf" uniqKey="Gyllensten U" first="Ulf" last="Gyllensten">Ulf Gyllensten</name><affiliation><nlm:aff id="A136">Uppsala University, Department of Immunology, Genetics, Pathology, SciLifeLab, Rudbeck Laboratory, SE-751 85 Uppsala, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Hall, Alistair S" sort="Hall, Alistair S" uniqKey="Hall A" first="Alistair S." last="Hall">Alistair S. Hall</name><affiliation><nlm:aff id="A246">Leeds MRC Medical Bioinformatics Centre, University of Leeds, Leeds LS2 9LU, UK.</nlm:aff></affiliation></author><author><name sortKey="Harris, Tamara B" sort="Harris, Tamara B" uniqKey="Harris T" first="Tamara B." last="Harris">Tamara B. Harris</name><affiliation><nlm:aff id="A109">Laboratory of Epidemiology and Population Sciences, National Institute on Aging, NIH, Bethesda, Maryland 20892, USA.</nlm:aff></affiliation></author><author><name sortKey="Hattersley, Andrew T" sort="Hattersley, Andrew T" uniqKey="Hattersley A" first="Andrew T." last="Hattersley">Andrew T. Hattersley</name><affiliation><nlm:aff id="A247">Institute of Biomedical & Clinical Science, University of Exeter, Barrack Road, Exeter EX2 5DW, UK.</nlm:aff></affiliation></author><author><name sortKey="Hicks, Andrew A" sort="Hicks, Andrew A" uniqKey="Hicks A" first="Andrew A." last="Hicks">Andrew A. Hicks</name><affiliation><nlm:aff id="A248">Center for Biomedicine, European Academy Bozen, Bolzano (EURAC), Bolzano 39100, Italy (affiliated institute of the University of Lübeck, D-23562 Lübeck, Germany).</nlm:aff></affiliation></author><author><name sortKey="Hindorff, Lucia A" sort="Hindorff, Lucia A" uniqKey="Hindorff L" first="Lucia A." last="Hindorff">Lucia A. Hindorff</name><affiliation><nlm:aff id="A249">Division of Genomic Medicine, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.</nlm:aff></affiliation></author><author><name sortKey="Hingorani, Aroon D" sort="Hingorani, Aroon D" uniqKey="Hingorani A" first="Aroon D." last="Hingorani">Aroon D. Hingorani</name><affiliation><nlm:aff id="A250">Institute of Cardiovascular Science, University College London, London WC1E 6BT, UK.</nlm:aff></affiliation></author><author><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name><affiliation><nlm:aff id="A58">Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A59">Department of Epidemiology, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Homuth, Georg" sort="Homuth, Georg" uniqKey="Homuth G" first="Georg" last="Homuth">Georg Homuth</name><affiliation><nlm:aff id="A73">Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, D-17475 Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Hovingh, G Kees" sort="Hovingh, G Kees" uniqKey="Hovingh G" first="G. Kees" last="Hovingh">G. Kees Hovingh</name><affiliation><nlm:aff id="A251">Department of Vascular Medicine, Academic Medical Center, 1105 AZ Amsterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Humphries, Steve E" sort="Humphries, Steve E" uniqKey="Humphries S" first="Steve E." last="Humphries">Steve E. Humphries</name><affiliation><nlm:aff id="A252">Centre for Cardiovascular Genetics, Institute Cardiovascular Sciences, University College London, London WC1E 6JJ, UK.</nlm:aff></affiliation></author><author><name sortKey="Hunt, Steven C" sort="Hunt, Steven C" uniqKey="Hunt S" first="Steven C." last="Hunt">Steven C. Hunt</name><affiliation><nlm:aff id="A253">Cardiovascular Genetics Division, Department of Internal Medicine, University of Utah, Salt Lake City, Utah 84108, USA.</nlm:aff></affiliation></author><author><name sortKey="Hypponen, Elina" sort="Hypponen, Elina" uniqKey="Hypponen E" first="Elina" last="Hyppönen">Elina Hyppönen</name><affiliation><nlm:aff id="A254">Sansom Institute for Health Research, University of South Australia, Adelaide 5000, South Australia, Australia.</nlm:aff></affiliation><affiliation><nlm:aff id="A255">School of Population Health, University of South Australia, Adelaide 5000, South Australia, Australia.</nlm:aff></affiliation><affiliation><nlm:aff id="A256">South Australian Health and Medical Research Institute, Adelaide, South Australia 5000, Australia.</nlm:aff></affiliation><affiliation><nlm:aff id="A257">Population, Policy, and Practice, University College London Institute of Child Health, London WC1N 1EH, UK.</nlm:aff></affiliation></author><author><name sortKey="Illig, Thomas" sort="Illig, Thomas" uniqKey="Illig T" first="Thomas" last="Illig">Thomas Illig</name><affiliation><nlm:aff id="A119">Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A258">Hannover Unified Biobank, Hannover Medical School, Hannover, D-30625 Hannover, Germany.</nlm:aff></affiliation></author><author><name sortKey="Jacobs, Kevin B" sort="Jacobs, Kevin B" uniqKey="Jacobs K" first="Kevin B." last="Jacobs">Kevin B. Jacobs</name><affiliation><nlm:aff id="A3">Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A79">Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland 21702, USA.</nlm:aff></affiliation></author><author><name sortKey="Jarvelin, Marjo Riitta" sort="Jarvelin, Marjo Riitta" uniqKey="Jarvelin M" first="Marjo-Riitta" last="Jarvelin">Marjo-Riitta Jarvelin</name><affiliation><nlm:aff id="A83">Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A259">National Institute for Health and Welfare, FI-90101 Oulu, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A260">MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College London, London W2 1PG, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A261">Unit of Primary Care, Oulu University Hospital, FI-90220 Oulu, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A263">Institute of Health Sciences, University of Oulu, FI-90014 Oulu, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A263">Institute of Health Sciences, University of Oulu, FI-90014 Oulu, Finland.</nlm:aff></affiliation></author><author><name sortKey="Jockel, Karl Heinz" sort="Jockel, Karl Heinz" uniqKey="Jockel K" first="Karl-Heinz" last="Jöckel">Karl-Heinz Jöckel</name><affiliation><nlm:aff id="A63">Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen, 45147 Essen, Germany.</nlm:aff></affiliation></author><author><name sortKey="Johansen, Berit" sort="Johansen, Berit" uniqKey="Johansen B" first="Berit" last="Johansen">Berit Johansen</name><affiliation><nlm:aff id="A101">Department of Biology, Norwegian University of Science and Technology, 7491 Trondheim, Norway.</nlm:aff></affiliation></author><author><name sortKey="Jousilahti, Pekka" sort="Jousilahti, Pekka" uniqKey="Jousilahti P" first="Pekka" last="Jousilahti">Pekka Jousilahti</name><affiliation><nlm:aff id="A53">National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:aff></affiliation></author><author><name sortKey="Jukema, J Wouter" sort="Jukema, J Wouter" uniqKey="Jukema J" first="J. Wouter" last="Jukema">J. Wouter Jukema</name><affiliation><nlm:aff id="A74">Department of Cardiology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A264">Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands (ICIN), 3501 DG Utrecht, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A265">Interuniversity Cardiology Institute of the Netherlands (ICIN), 3501 DG Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Jula, Antti M" sort="Jula, Antti M" uniqKey="Jula A" first="Antti M." last="Jula">Antti M. Jula</name><affiliation><nlm:aff id="A53">National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:aff></affiliation></author><author><name sortKey="Kaprio, Jaakko" sort="Kaprio, Jaakko" uniqKey="Kaprio J" first="Jaakko" last="Kaprio">Jaakko Kaprio</name><affiliation><nlm:aff id="A53">National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A107">Institute for Molecular Medicine, University of Helsinki, FI-00014 Helsinki, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A137">Hjelt Institute Department of Public Health, University of Helsinki, FI-00014 Helsinki, Finland.</nlm:aff></affiliation></author><author><name sortKey="Kastelein, John J P" sort="Kastelein, John J P" uniqKey="Kastelein J" first="John J. P." last="Kastelein">John J. P. Kastelein</name><affiliation><nlm:aff id="A251">Department of Vascular Medicine, Academic Medical Center, 1105 AZ Amsterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Keinanen Kiukaanniemi, Sirkka M" sort="Keinanen Kiukaanniemi, Sirkka M" uniqKey="Keinanen Kiukaanniemi S" first="Sirkka M." last="Keinanen-Kiukaanniemi">Sirkka M. Keinanen-Kiukaanniemi</name><affiliation><nlm:aff id="A263">Institute of Health Sciences, University of Oulu, FI-90014 Oulu, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A266">Unit of Primary Health Care/General Practice, Oulu University Hospital, FI-90220 Oulu, Finland.</nlm:aff></affiliation></author><author><name sortKey="Kiemeney, Lambertus A" sort="Kiemeney, Lambertus A" uniqKey="Kiemeney L" first="Lambertus A." last="Kiemeney">Lambertus A. Kiemeney</name><affiliation><nlm:aff id="A179">Department for Health Evidence, Radboud University Medical Centre, 6500 HB Nijmegen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A267">Department of Urology, Radboud University Medical Centre, 6500 HB Nijmegen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Knekt, Paul" sort="Knekt, Paul" uniqKey="Knekt P" first="Paul" last="Knekt">Paul Knekt</name><affiliation><nlm:aff id="A53">National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:aff></affiliation></author><author><name sortKey="Kooner, Jaspal S" sort="Kooner, Jaspal S" uniqKey="Kooner J" first="Jaspal S." last="Kooner">Jaspal S. Kooner</name><affiliation><nlm:aff id="A41">Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A173">National Heart and Lung Institute, Imperial College London, London SW3 6LY, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A268">Imperial College Healthcare NHS Trust, London W12 0HS, UK.</nlm:aff></affiliation></author><author><name sortKey="Kooperberg, Charles" sort="Kooperberg, Charles" uniqKey="Kooperberg C" first="Charles" last="Kooperberg">Charles Kooperberg</name><affiliation><nlm:aff id="A49">Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.</nlm:aff></affiliation></author><author><name sortKey="Kovacs, Peter" sort="Kovacs, Peter" uniqKey="Kovacs P" first="Peter" last="Kovacs">Peter Kovacs</name><affiliation><nlm:aff id="A96">Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, D-04103 Leipzig, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A97">Department of Medicine, University of Leipzig, D-04103 Leipzig, Germany.</nlm:aff></affiliation></author><author><name sortKey="Kraja, Aldi T" sort="Kraja, Aldi T" uniqKey="Kraja A" first="Aldi T." last="Kraja">Aldi T. Kraja</name><affiliation><nlm:aff id="A47">Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:aff></affiliation></author><author><name sortKey="Kumari, Meena" sort="Kumari, Meena" uniqKey="Kumari M" first="Meena" last="Kumari">Meena Kumari</name><affiliation><nlm:aff id="A269">Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A270">Department of Biological and Social Epidemiology, University of Essex, Wivenhoe Park, Colchester, Essex CO4 3SQ, UK.</nlm:aff></affiliation></author><author><name sortKey="Kuusisto, Johanna" sort="Kuusisto, Johanna" uniqKey="Kuusisto J" first="Johanna" last="Kuusisto">Johanna Kuusisto</name><affiliation><nlm:aff id="A271">Department of Medicine, Kuopio University Hospital and University of Eastern Finland, FI-70210 Kuopio, Finland.</nlm:aff></affiliation></author><author><name sortKey="Lakka, Timo A" sort="Lakka, Timo A" uniqKey="Lakka T" first="Timo A." last="Lakka">Timo A. Lakka</name><affiliation><nlm:aff id="A125">Kuopio Research Institute of Exercise Medicine, 70100 Kuopio, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A272">Department of Physiology, Institute of Biomedicine, University of Eastern Finland, Kuopio Campus, FI-70211 Kuopio, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A273">Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital and University of Eastern Finland, FI-70210 Kuopio, Finland.</nlm:aff></affiliation></author><author><name sortKey="Langenberg, Claudia" sort="Langenberg, Claudia" uniqKey="Langenberg C" first="Claudia" last="Langenberg">Claudia Langenberg</name><affiliation><nlm:aff id="A9">MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A269">Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK.</nlm:aff></affiliation></author><author><name sortKey="Marchand, Loic Le" sort="Marchand, Loic Le" uniqKey="Marchand L" first="Loic Le" last="Marchand">Loic Le Marchand</name><affiliation><nlm:aff id="A54">Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96813, USA.</nlm:aff></affiliation></author><author><name sortKey="Lehtim Ki, Terho" sort="Lehtim Ki, Terho" uniqKey="Lehtim Ki T" first="Terho" last="Lehtim Ki">Terho Lehtim Ki</name><affiliation><nlm:aff id="A274">Department of Clinical Chemistry, Fimlab Laboratories and School of Medicine University of Tampere, FI-33520 Tampere, Finland.</nlm:aff></affiliation></author><author><name sortKey="Lyssenko, Valeriya" sort="Lyssenko, Valeriya" uniqKey="Lyssenko V" first="Valeriya" last="Lyssenko">Valeriya Lyssenko</name><affiliation><nlm:aff id="A275">Steno Diabetes Center A/S, Gentofte DK-2820, Denmark.</nlm:aff></affiliation><affiliation><nlm:aff id="A276">Lund University Diabetes Centre and Department of Clinical Science, Diabetes & Endocrinology Unit, Lund University, Malmö 221 00, Sweden.</nlm:aff></affiliation></author><author><name sortKey="M Nnisto, Satu" sort="M Nnisto, Satu" uniqKey="M Nnisto S" first="Satu" last="M Nnistö">Satu M Nnistö</name><affiliation><nlm:aff id="A53">National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:aff></affiliation></author><author><name sortKey="Marette, Andre" sort="Marette, Andre" uniqKey="Marette A" first="André" last="Marette">André Marette</name><affiliation><nlm:aff id="A277">Institut Universitaire de Cardiologie et de Pneumologie de Québec, Faculty of Medicine, Laval University, Quebec, QC G1V 0A6, Canada.</nlm:aff></affiliation><affiliation><nlm:aff id="A278">Institute of Nutrition and Functional Foods, Laval University, Quebec, QC G1V 0A6, Canada.</nlm:aff></affiliation></author><author><name sortKey="Matise, Tara C" sort="Matise, Tara C" uniqKey="Matise T" first="Tara C." last="Matise">Tara C. Matise</name><affiliation><nlm:aff id="A39">Department of Genetics, Rutgers University, Piscataway, New Jersey 08854, USA.</nlm:aff></affiliation></author><author><name sortKey="Mckenzie, Colin A" sort="Mckenzie, Colin A" uniqKey="Mckenzie C" first="Colin A." last="Mckenzie">Colin A. Mckenzie</name><affiliation><nlm:aff id="A244">UWI Solutions for Developing Countries, The University of the West Indies, Mona, Kingston 7, Jamaica.</nlm:aff></affiliation></author><author><name sortKey="Mcknight, Barbara" sort="Mcknight, Barbara" uniqKey="Mcknight B" first="Barbara" last="Mcknight">Barbara Mcknight</name><affiliation><nlm:aff id="A279">Department of Biostatistics, University of Washington, Seattle, Washington 98195, USA.</nlm:aff></affiliation></author><author><name sortKey="Moll, Frans L" sort="Moll, Frans L" uniqKey="Moll F" first="Frans L." last="Moll">Frans L. Moll</name><affiliation><nlm:aff id="A280">Department of Surgery, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Morris, Andrew D" sort="Morris, Andrew D" uniqKey="Morris A" first="Andrew D." last="Morris">Andrew D. Morris</name><affiliation><nlm:aff id="A106">Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.</nlm:aff></affiliation></author><author><name sortKey="Morris, Andrew P" sort="Morris, Andrew P" uniqKey="Morris A" first="Andrew P." last="Morris">Andrew P. Morris</name><affiliation><nlm:aff id="A14">Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.</nlm:aff></affiliation><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A281">Department of Biostatistics, University of Liverpool, Liverpool L69 3GA, UK.</nlm:aff></affiliation></author><author><name sortKey="Murray, Jeffrey C" sort="Murray, Jeffrey C" uniqKey="Murray J" first="Jeffrey C." last="Murray">Jeffrey C. Murray</name><affiliation><nlm:aff id="A282">Department of Pediatrics, University of Iowa, Iowa City, Iowa 52242, USA.</nlm:aff></affiliation></author><author><name sortKey="Nelis, Mari" sort="Nelis, Mari" uniqKey="Nelis M" first="Mari" last="Nelis">Mari Nelis</name><affiliation><nlm:aff id="A14">Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.</nlm:aff></affiliation></author><author><name sortKey="Ohlsson, Claes" sort="Ohlsson, Claes" uniqKey="Ohlsson C" first="Claes" last="Ohlsson">Claes Ohlsson</name><affiliation><nlm:aff id="A177">Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg 413 45, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Oldehinkel, Albertine J" sort="Oldehinkel, Albertine J" uniqKey="Oldehinkel A" first="Albertine J." last="Oldehinkel">Albertine J. Oldehinkel</name><affiliation><nlm:aff id="A124">Department of Psychiatry, University of Groningen, University Medical Center Groningen, 9700RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Ong, Ken K" sort="Ong, Ken K" uniqKey="Ong K" first="Ken K." last="Ong">Ken K. Ong</name><affiliation><nlm:aff id="A9">MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A186">MRC Unit for Lifelong Health and Ageing at University College London, London WC1B 5JU, UK.</nlm:aff></affiliation></author><author><name sortKey="Madden, Pamela A F" sort="Madden, Pamela A F" uniqKey="Madden P" first="Pamela A. F." last="Madden">Pamela A. F. Madden</name><affiliation><nlm:aff id="A218">Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:aff></affiliation></author><author><name sortKey="Pasterkamp, Gerard" sort="Pasterkamp, Gerard" uniqKey="Pasterkamp G" first="Gerard" last="Pasterkamp">Gerard Pasterkamp</name><affiliation><nlm:aff id="A76">Experimental Cardiology Laboratory, Division Heart and Lungs, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Peden, John F" sort="Peden, John F" uniqKey="Peden J" first="John F." last="Peden">John F. Peden</name><affiliation><nlm:aff id="A283">Illumina, Inc, Little Chesterford, Cambridge CB10 1XL, UK.</nlm:aff></affiliation></author><author><name sortKey="Peters, Annette" sort="Peters, Annette" uniqKey="Peters A" first="Annette" last="Peters">Annette Peters</name><affiliation><nlm:aff id="A119">Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A130">Deutsches Forschungszentrum für Herz-Kreislauferkrankungen (DZHK) (German Research Centre for Cardiovascular Research), Munich Heart Alliance, D-80636 Munich, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A175">Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany, D-85764 Neuherberg, Germany.</nlm:aff></affiliation></author><author><name sortKey="Postma, Dirkje S" sort="Postma, Dirkje S" uniqKey="Postma D" first="Dirkje S." last="Postma">Dirkje S. Postma</name><affiliation><nlm:aff id="A284">University of Groningen, University Medical Center Groningen, Department of Pulmonary Medicine and Tuberculosis, Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Pramstaller, Peter P" sort="Pramstaller, Peter P" uniqKey="Pramstaller P" first="Peter P." last="Pramstaller">Peter P. Pramstaller</name><affiliation><nlm:aff id="A248">Center for Biomedicine, European Academy Bozen, Bolzano (EURAC), Bolzano 39100, Italy (affiliated institute of the University of Lübeck, D-23562 Lübeck, Germany).</nlm:aff></affiliation><affiliation><nlm:aff id="A285">Department of Neurology, General Central Hospital, Bolzano 39100, Italy.</nlm:aff></affiliation></author><author><name sortKey="Price, Jackie F" sort="Price, Jackie F" uniqKey="Price J" first="Jackie F." last="Price">Jackie F. Price</name><affiliation><nlm:aff id="A36">Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK.</nlm:aff></affiliation></author><author><name sortKey="Qi, Lu" sort="Qi, Lu" uniqKey="Qi L" first="Lu" last="Qi">Lu Qi</name><affiliation><nlm:aff id="A13">Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A25">Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation></author><author><name sortKey="Raitakari, Olli T" sort="Raitakari, Olli T" uniqKey="Raitakari O" first="Olli T." last="Raitakari">Olli T. Raitakari</name><affiliation><nlm:aff id="A286">Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, FI-20521 Turku, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A287">Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, FI-20521 Turku, Finland.</nlm:aff></affiliation></author><author><name sortKey="Rankinen, Tuomo" sort="Rankinen, Tuomo" uniqKey="Rankinen T" first="Tuomo" last="Rankinen">Tuomo Rankinen</name><affiliation><nlm:aff id="A288">Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808, USA.</nlm:aff></affiliation></author><author><name sortKey="Rao, D C" sort="Rao, D C" uniqKey="Rao D" first="D. C." last="Rao">D. C. Rao</name><affiliation><nlm:aff id="A47">Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A71">Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A218">Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:aff></affiliation></author><author><name sortKey="Rice, Treva K" sort="Rice, Treva K" uniqKey="Rice T" first="Treva K." last="Rice">Treva K. Rice</name><affiliation><nlm:aff id="A71">Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A218">Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:aff></affiliation></author><author><name sortKey="Ridker, Paul M" sort="Ridker, Paul M" uniqKey="Ridker P" first="Paul M." last="Ridker">Paul M. Ridker</name><affiliation><nlm:aff id="A163">Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, Massachusetts 02215, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A226">Harvard Medical School, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation></author><author><name sortKey="Rioux, John D" sort="Rioux, John D" uniqKey="Rioux J" first="John D." last="Rioux">John D. Rioux</name><affiliation><nlm:aff id="A143">Montreal Heart Institute, Montreal, Quebec H1T 1C8, Canada.</nlm:aff></affiliation><affiliation><nlm:aff id="A289">Université de Montréal, Montreal, Quebec H1T 1C8, Canada.</nlm:aff></affiliation></author><author><name sortKey="Ritchie, Marylyn D" sort="Ritchie, Marylyn D" uniqKey="Ritchie M" first="Marylyn D." last="Ritchie">Marylyn D. Ritchie</name><affiliation><nlm:aff id="A290">Center for Systems Genomics, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.</nlm:aff></affiliation></author><author><name sortKey="Rudan, Igor" sort="Rudan, Igor" uniqKey="Rudan I" first="Igor" last="Rudan">Igor Rudan</name><affiliation><nlm:aff id="A36">Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A291">Croatian Centre for Global Health, Faculty of Medicine, University of Split, 21000 Split, Croatia.</nlm:aff></affiliation></author><author><name sortKey="Salomaa, Veikko" sort="Salomaa, Veikko" uniqKey="Salomaa V" first="Veikko" last="Salomaa">Veikko Salomaa</name><affiliation><nlm:aff id="A53">National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:aff></affiliation></author><author><name sortKey="Samani, Nilesh J" sort="Samani, Nilesh J" uniqKey="Samani N" first="Nilesh J." last="Samani">Nilesh J. Samani</name><affiliation><nlm:aff id="A114">Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester LE3 9QP, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A115">National Institute for Health Research (NIHR) Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester LE3 9QP, UK.</nlm:aff></affiliation></author><author><name sortKey="Saramies, Jouko" sort="Saramies, Jouko" uniqKey="Saramies J" first="Jouko" last="Saramies">Jouko Saramies</name><affiliation><nlm:aff id="A292">South Carelia Central Hospital, 53130 Lappeenranta, Finland.</nlm:aff></affiliation></author><author><name sortKey="Sarzynski, Mark A" sort="Sarzynski, Mark A" uniqKey="Sarzynski M" first="Mark A." last="Sarzynski">Mark A. Sarzynski</name><affiliation><nlm:aff id="A288">Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808, USA.</nlm:aff></affiliation></author><author><name sortKey="Schunkert, Heribert" sort="Schunkert, Heribert" uniqKey="Schunkert H" first="Heribert" last="Schunkert">Heribert Schunkert</name><affiliation><nlm:aff id="A130">Deutsches Forschungszentrum für Herz-Kreislauferkrankungen (DZHK) (German Research Centre for Cardiovascular Research), Munich Heart Alliance, D-80636 Munich, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A131">Deutsches Herzzentrum München, Technische Universität München, D-80636 Munich, Germany.</nlm:aff></affiliation></author><author><name sortKey="Schwarz, Peter E H" sort="Schwarz, Peter E H" uniqKey="Schwarz P" first="Peter E. H." last="Schwarz">Peter E. H. Schwarz</name><affiliation><nlm:aff id="A121">Department of Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, D-01307 Dresden, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A293">Paul Langerhans Institute Dresden, German Center for Diabetes Research (DZD), 01307 Dresden, Germany.</nlm:aff></affiliation></author><author><name sortKey="Sever, Peter" sort="Sever, Peter" uniqKey="Sever P" first="Peter" last="Sever">Peter Sever</name><affiliation><nlm:aff id="A294">International Centre for Circulatory Health, Imperial College London, London W2 1PG, UK.</nlm:aff></affiliation></author><author><name sortKey="Shuldiner, Alan R" sort="Shuldiner, Alan R" uniqKey="Shuldiner A" first="Alan R." last="Shuldiner">Alan R. Shuldiner</name><affiliation><nlm:aff id="A295">Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A296">Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A297">Geriatric Research and Education Clinical Center, Vetrans Administration Medical Center, Baltimore, Maryland 21201, USA.</nlm:aff></affiliation></author><author><name sortKey="Sinisalo, Juha" sort="Sinisalo, Juha" uniqKey="Sinisalo J" first="Juha" last="Sinisalo">Juha Sinisalo</name><affiliation><nlm:aff id="A298">Helsinki University Central Hospital Heart and Lung Center, Department of Medicine, Helsinki University Central Hospital, FI-00290 Helsinki, Finland.</nlm:aff></affiliation></author><author><name sortKey="Stolk, Ronald P" sort="Stolk, Ronald P" uniqKey="Stolk R" first="Ronald P." last="Stolk">Ronald P. Stolk</name><affiliation><nlm:aff id="A169">Department of Epidemiology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Strauch, Konstantin" sort="Strauch, Konstantin" uniqKey="Strauch K" first="Konstantin" last="Strauch">Konstantin Strauch</name><affiliation><nlm:aff id="A85">Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A153">Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, D-81377 Munich, Germany.</nlm:aff></affiliation></author><author><name sortKey="Tonjes, Anke" sort="Tonjes, Anke" uniqKey="Tonjes A" first="Anke" last="Tönjes">Anke Tönjes</name><affiliation><nlm:aff id="A96">Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, D-04103 Leipzig, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A97">Department of Medicine, University of Leipzig, D-04103 Leipzig, Germany.</nlm:aff></affiliation></author><author><name sortKey="Tregouet, David Alexandre" sort="Tregouet, David Alexandre" uniqKey="Tregouet D" first="David-Alexandre" last="Trégouët">David-Alexandre Trégouët</name><affiliation><nlm:aff id="A299">Sorbonne Universités, UPMC Univ Paris 06, UMR S 1166, F-75013 Paris, France.</nlm:aff></affiliation><affiliation><nlm:aff id="A300">INSERM, UMR S 1166, Team Genomics and Physiopathology of Cardiovascular Diseases, F-75013 Paris, France.</nlm:aff></affiliation><affiliation><nlm:aff id="A301">Institute for Cardiometabolism And Nutrition (ICAN), F-75013 Paris, France.</nlm:aff></affiliation></author><author><name sortKey="Tremblay, Angelo" sort="Tremblay, Angelo" uniqKey="Tremblay A" first="Angelo" last="Tremblay">Angelo Tremblay</name><affiliation><nlm:aff id="A302">Department of Kinesiology, Laval University, Quebec QC G1V 0A6, Canada.</nlm:aff></affiliation></author><author><name sortKey="Tremoli, Elena" sort="Tremoli, Elena" uniqKey="Tremoli E" first="Elena" last="Tremoli">Elena Tremoli</name><affiliation><nlm:aff id="A303">Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano & Centro Cardiologico Monzino, Instituto di Ricovero e Cura a Carattere Scientifico, Milan 20133, Italy.</nlm:aff></affiliation></author><author><name sortKey="Virtamo, Jarmo" sort="Virtamo, Jarmo" uniqKey="Virtamo J" first="Jarmo" last="Virtamo">Jarmo Virtamo</name><affiliation><nlm:aff id="A53">National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:aff></affiliation></author><author><name sortKey="Vohl, Marie Claude" sort="Vohl, Marie Claude" uniqKey="Vohl M" first="Marie-Claude" last="Vohl">Marie-Claude Vohl</name><affiliation><nlm:aff id="A278">Institute of Nutrition and Functional Foods, Laval University, Quebec, QC G1V 0A6, Canada.</nlm:aff></affiliation><affiliation><nlm:aff id="A304">Department of Food Science and Nutrition, Laval University, Quebec QC G1V 0A6, Canada.</nlm:aff></affiliation></author><author><name sortKey="Volker, Uwe" sort="Volker, Uwe" uniqKey="Volker U" first="Uwe" last="Völker">Uwe Völker</name><affiliation><nlm:aff id="A73">Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, D-17475 Greifswald, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A239">DZHK (Deutsches Zentrum für Herz-Kreislaufforschung – German Centre for Cardiovascular Research), partner site Greifswald, D-17475 Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Waeber, Gerard" sort="Waeber, Gerard" uniqKey="Waeber G" first="Gérard" last="Waeber">Gérard Waeber</name><affiliation><nlm:aff id="A305">Department of Internal Medicine, University Hospital (CHUV) and University of Lausanne, Lausanne 1011, Switzerland.</nlm:aff></affiliation></author><author><name sortKey="Willemsen, Gonneke" sort="Willemsen, Gonneke" uniqKey="Willemsen G" first="Gonneke" last="Willemsen">Gonneke Willemsen</name><affiliation><nlm:aff id="A133">Biological Psychology, VU University Amsterdam, 1081BT Amsterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Witteman, Jacqueline C" sort="Witteman, Jacqueline C" uniqKey="Witteman J" first="Jacqueline C." last="Witteman">Jacqueline C. Witteman</name><affiliation><nlm:aff id="A59">Department of Epidemiology, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Zillikens, M Carola" sort="Zillikens, M Carola" uniqKey="Zillikens M" first="M. Carola" last="Zillikens">M. Carola Zillikens</name><affiliation><nlm:aff id="A58">Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A60">Department of Internal Medicine, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Adair, Linda S" sort="Adair, Linda S" uniqKey="Adair L" first="Linda S." last="Adair">Linda S. Adair</name><affiliation><nlm:aff id="A306">Department of Nutrition, University of North Carolina, Chapel Hill, North Carolina 27599, USA.</nlm:aff></affiliation></author><author><name sortKey="Amouyel, Philippe" sort="Amouyel, Philippe" uniqKey="Amouyel P" first="Philippe" last="Amouyel">Philippe Amouyel</name><affiliation><nlm:aff id="A307">Institut Pasteur de Lille; INSERM, U744; Université de Lille 2; F-59000 Lille, France.</nlm:aff></affiliation></author><author><name sortKey="Asselbergs, Folkert W" sort="Asselbergs, Folkert W" uniqKey="Asselbergs F" first="Folkert W." last="Asselbergs">Folkert W. Asselbergs</name><affiliation><nlm:aff id="A250">Institute of Cardiovascular Science, University College London, London WC1E 6BT, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A264">Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands (ICIN), 3501 DG Utrecht, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A308">Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Assimes, Themistocles L" sort="Assimes, Themistocles L" uniqKey="Assimes T" first="Themistocles L." last="Assimes">Themistocles L. Assimes</name><affiliation><nlm:aff id="A309">Department of Medicine, Stanford University School of Medicine, Palo Alto, California 94304, USA.</nlm:aff></affiliation></author><author><name sortKey="Bochud, Murielle" sort="Bochud, Murielle" uniqKey="Bochud M" first="Murielle" last="Bochud">Murielle Bochud</name><affiliation><nlm:aff id="A223">Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois and University of Lausanne, 1010 Lausanne, Switzerland.</nlm:aff></affiliation><affiliation><nlm:aff id="A224">Ministry of Health, Victoria, Republic of Seychelles.</nlm:aff></affiliation></author><author><name sortKey="Boehm, Bernhard O" sort="Boehm, Bernhard O" uniqKey="Boehm B" first="Bernhard O." last="Boehm">Bernhard O. Boehm</name><affiliation><nlm:aff id="A310">Lee Kong Chian School of Medicine, Imperial College London and Nanyang Technological University, Singapore, 637553 Singapore, Singapore.</nlm:aff></affiliation><affiliation><nlm:aff id="A311">Department of Internal Medicine I, Ulm University Medical Centre, D-89081 Ulm, Germany.</nlm:aff></affiliation></author><author><name sortKey="Boerwinkle, Eric" sort="Boerwinkle, Eric" uniqKey="Boerwinkle E" first="Eric" last="Boerwinkle">Eric Boerwinkle</name><affiliation><nlm:aff id="A312">Health Science Center at Houston, University of Texas, Houston, Texas 77030, USA.</nlm:aff></affiliation></author><author><name sortKey="Bornstein, Stefan R" sort="Bornstein, Stefan R" uniqKey="Bornstein S" first="Stefan R." last="Bornstein">Stefan R. Bornstein</name><affiliation><nlm:aff id="A121">Department of Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, D-01307 Dresden, Germany.</nlm:aff></affiliation></author><author><name sortKey="Bottinger, Erwin P" sort="Bottinger, Erwin P" uniqKey="Bottinger E" first="Erwin P." last="Bottinger">Erwin P. Bottinger</name><affiliation><nlm:aff id="A55">The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:aff></affiliation></author><author><name sortKey="Bouchard, Claude" sort="Bouchard, Claude" uniqKey="Bouchard C" first="Claude" last="Bouchard">Claude Bouchard</name><affiliation><nlm:aff id="A288">Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808, USA.</nlm:aff></affiliation></author><author><name sortKey="Cauchi, Stephane" sort="Cauchi, Stephane" uniqKey="Cauchi S" first="Stéphane" last="Cauchi">Stéphane Cauchi</name><affiliation><nlm:aff id="A80">CNRS UMR 8199, F-59019 Lille, France.</nlm:aff></affiliation><affiliation><nlm:aff id="A81">European Genomic Institute for Diabetes, F-59000 Lille, France.</nlm:aff></affiliation><affiliation><nlm:aff id="A82">Université de Lille 2, F-59000 Lille, France.</nlm:aff></affiliation></author><author><name sortKey="Chambers, John C" sort="Chambers, John C" uniqKey="Chambers J" first="John C." last="Chambers">John C. Chambers</name><affiliation><nlm:aff id="A41">Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A83">Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A268">Imperial College Healthcare NHS Trust, London W12 0HS, UK.</nlm:aff></affiliation></author><author><name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J." last="Chanock">Stephen J. Chanock</name><affiliation><nlm:aff id="A3">Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.</nlm:aff></affiliation></author><author><name sortKey="Cooper, Richard S" sort="Cooper, Richard S" uniqKey="Cooper R" first="Richard S." last="Cooper">Richard S. Cooper</name><affiliation><nlm:aff id="A174">Department of Public Health Sciences, Stritch School of Medicine, Loyola University of Chicago, Maywood, Illinois 61053, USA.</nlm:aff></affiliation></author><author><name sortKey="De Bakker, Paul I W" sort="De Bakker, Paul I W" uniqKey="De Bakker P" first="Paul I. W." last="De Bakker">Paul I. W. De Bakker</name><affiliation><nlm:aff id="A77">Department of Medical Genetics, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A313">Department of Medicine, Division of Genetics, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A314">Department of Epidemiology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Dedoussis, George" sort="Dedoussis, George" uniqKey="Dedoussis G" first="George" last="Dedoussis">George Dedoussis</name><affiliation><nlm:aff id="A105">Department of Dietetics-Nutrition, Harokopio University, 17671 Athens, Greece.</nlm:aff></affiliation></author><author><name sortKey="Ferrucci, Luigi" sort="Ferrucci, Luigi" uniqKey="Ferrucci L" first="Luigi" last="Ferrucci">Luigi Ferrucci</name><affiliation><nlm:aff id="A72">Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland 21225, USA.</nlm:aff></affiliation></author><author><name sortKey="Franks, Paul W" sort="Franks, Paul W" uniqKey="Franks P" first="Paul W." last="Franks">Paul W. Franks</name><affiliation><nlm:aff id="A25">Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A66">Department of Clinical Sciences, Genetic & Molecular Epidemiology Unit, Lund University Diabetes Center, Skåne University Hosptial, Malmö 205 02, Sweden.</nlm:aff></affiliation><affiliation><nlm:aff id="A67">Department of Public Health and Clinical Medicine, Unit of Medicine, Umeå University, Umeå 901 87, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Froguel, Philippe" sort="Froguel, Philippe" uniqKey="Froguel P" first="Philippe" last="Froguel">Philippe Froguel</name><affiliation><nlm:aff id="A65">Department of Genomics of Common Disease, School of Public Health, Imperial College London, Hammersmith Hospital, London W12 0NN, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A80">CNRS UMR 8199, F-59019 Lille, France.</nlm:aff></affiliation><affiliation><nlm:aff id="A81">European Genomic Institute for Diabetes, F-59000 Lille, France.</nlm:aff></affiliation><affiliation><nlm:aff id="A82">Université de Lille 2, F-59000 Lille, France.</nlm:aff></affiliation></author><author><name sortKey="Groop, Leif C" sort="Groop, Leif C" uniqKey="Groop L" first="Leif C." last="Groop">Leif C. Groop</name><affiliation><nlm:aff id="A107">Institute for Molecular Medicine, University of Helsinki, FI-00014 Helsinki, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A276">Lund University Diabetes Centre and Department of Clinical Science, Diabetes & Endocrinology Unit, Lund University, Malmö 221 00, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Haiman, Christopher A" sort="Haiman, Christopher A" uniqKey="Haiman C" first="Christopher A." last="Haiman">Christopher A. Haiman</name><affiliation><nlm:aff id="A165">Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA.</nlm:aff></affiliation></author><author><name sortKey="Hamsten, Anders" sort="Hamsten, Anders" uniqKey="Hamsten A" first="Anders" last="Hamsten">Anders Hamsten</name><affiliation><nlm:aff id="A70">Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm 17176, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Hui, Jennie" sort="Hui, Jennie" uniqKey="Hui J" first="Jennie" last="Hui">Jennie Hui</name><affiliation><nlm:aff id="A87">PathWest Laboratory Medicine of Western Australia, Nedlands, Western Australia 6009, Australia.</nlm:aff></affiliation><affiliation><nlm:aff id="A221">Pathology and Laboratory Medicine, The University of Western Australia, Perth, Western Australia 6009, Australia.</nlm:aff></affiliation><affiliation><nlm:aff id="A315">School of Population Health, The University of Western Australia, Nedlands, Western Australia 6009, Australia.</nlm:aff></affiliation></author><author><name sortKey="Hunter, David J" sort="Hunter, David J" uniqKey="Hunter D" first="David J." last="Hunter">David J. Hunter</name><affiliation><nlm:aff id="A13">Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A25">Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A194">Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation></author><author><name sortKey="Hveem, Kristian" sort="Hveem, Kristian" uniqKey="Hveem K" first="Kristian" last="Hveem">Kristian Hveem</name><affiliation><nlm:aff id="A132">Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim 7489, Norway.</nlm:aff></affiliation></author><author><name sortKey="Kaplan, Robert C" sort="Kaplan, Robert C" uniqKey="Kaplan R" first="Robert C." last="Kaplan">Robert C. Kaplan</name><affiliation><nlm:aff id="A316">Albert Einstein College of Medicine, Department of Epidemiology and Population Health, Belfer 1306, New York 10461, USA.</nlm:aff></affiliation></author><author><name sortKey="Kivimaki, Mika" sort="Kivimaki, Mika" uniqKey="Kivimaki M" first="Mika" last="Kivimaki">Mika Kivimaki</name><affiliation><nlm:aff id="A269">Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK.</nlm:aff></affiliation></author><author><name sortKey="Kuh, Diana" sort="Kuh, Diana" uniqKey="Kuh D" first="Diana" last="Kuh">Diana Kuh</name><affiliation><nlm:aff id="A186">MRC Unit for Lifelong Health and Ageing at University College London, London WC1B 5JU, UK.</nlm:aff></affiliation></author><author><name sortKey="Laakso, Markku" sort="Laakso, Markku" uniqKey="Laakso M" first="Markku" last="Laakso">Markku Laakso</name><affiliation><nlm:aff id="A271">Department of Medicine, Kuopio University Hospital and University of Eastern Finland, FI-70210 Kuopio, Finland.</nlm:aff></affiliation></author><author><name sortKey="Liu, Yongmei" sort="Liu, Yongmei" uniqKey="Liu Y" first="Yongmei" last="Liu">Yongmei Liu</name><affiliation><nlm:aff id="A317">Center for Human Genetics, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, USA.</nlm:aff></affiliation></author><author><name sortKey="Martin, Nicholas G" sort="Martin, Nicholas G" uniqKey="Martin N" first="Nicholas G." last="Martin">Nicholas G. Martin</name><affiliation><nlm:aff id="A61">QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4006, Australia.</nlm:aff></affiliation></author><author><name sortKey="M Rz, Winfried" sort="M Rz, Winfried" uniqKey="M Rz W" first="Winfried" last="M Rz">Winfried M Rz</name><affiliation><nlm:aff id="A51">Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, D-68187 Mannheim, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A164">Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz 8036, Austria.</nlm:aff></affiliation><affiliation><nlm:aff id="A318">Synlab Academy, Synlab Services GmbH, 68163 Mannheim, Germany.</nlm:aff></affiliation></author><author><name sortKey="Melbye, Mads" sort="Melbye, Mads" uniqKey="Melbye M" first="Mads" last="Melbye">Mads Melbye</name><affiliation><nlm:aff id="A309">Department of Medicine, Stanford University School of Medicine, Palo Alto, California 94304, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A319">Department of Clinical Medicine, Copenhagen University, 2200 Copenhagen, Denmark.</nlm:aff></affiliation></author><author><name sortKey="Metspalu, Andres" sort="Metspalu, Andres" uniqKey="Metspalu A" first="Andres" last="Metspalu">Andres Metspalu</name><affiliation><nlm:aff id="A14">Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.</nlm:aff></affiliation><affiliation><nlm:aff id="A147">Institute of Molecular and Cell Biology, University of Tartu, Tartu 51010, Estonia.</nlm:aff></affiliation></author><author><name sortKey="Moebus, Susanne" sort="Moebus, Susanne" uniqKey="Moebus S" first="Susanne" last="Moebus">Susanne Moebus</name><affiliation><nlm:aff id="A63">Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen, 45147 Essen, Germany.</nlm:aff></affiliation></author><author><name sortKey="Munroe, Patricia B" sort="Munroe, Patricia B" uniqKey="Munroe P" first="Patricia B." last="Munroe">Patricia B. Munroe</name><affiliation><nlm:aff id="A181">Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.</nlm:aff></affiliation></author><author><name sortKey="Nj Lstad, Inger" sort="Nj Lstad, Inger" uniqKey="Nj Lstad I" first="Inger" last="Nj Lstad">Inger Nj Lstad</name><affiliation><nlm:aff id="A185">Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, 9037 Tromsø, Norway.</nlm:aff></affiliation></author><author><name sortKey="Oostra, Ben A" sort="Oostra, Ben A" uniqKey="Oostra B" first="Ben A." last="Oostra">Ben A. Oostra</name><affiliation><nlm:aff id="A32">Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC University Medical Center, 3015 GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A84">Center for Medical Sytems Biology, 2300 RC Leiden, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A320">Department of Clinical Genetics, Erasmus MC University Medical Center, 3000 CA Rotterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Palmer, Colin N A" sort="Palmer, Colin N A" uniqKey="Palmer C" first="Colin N. A." last="Palmer">Colin N. A. Palmer</name><affiliation><nlm:aff id="A106">Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.</nlm:aff></affiliation></author><author><name sortKey="Pedersen, Nancy L" sort="Pedersen, Nancy L" uniqKey="Pedersen N" first="Nancy L." last="Pedersen">Nancy L. Pedersen</name><affiliation><nlm:aff id="A15">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden.</nlm:aff></affiliation></author><author><name sortKey="Perola, Markus" sort="Perola, Markus" uniqKey="Perola M" first="Markus" last="Perola">Markus Perola</name><affiliation><nlm:aff id="A14">Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.</nlm:aff></affiliation><affiliation><nlm:aff id="A53">National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A107">Institute for Molecular Medicine, University of Helsinki, FI-00014 Helsinki, Finland.</nlm:aff></affiliation></author><author><name sortKey="Perusse, Louis" sort="Perusse, Louis" uniqKey="Perusse L" first="Louis" last="Pérusse">Louis Pérusse</name><affiliation><nlm:aff id="A278">Institute of Nutrition and Functional Foods, Laval University, Quebec, QC G1V 0A6, Canada.</nlm:aff></affiliation><affiliation><nlm:aff id="A302">Department of Kinesiology, Laval University, Quebec QC G1V 0A6, Canada.</nlm:aff></affiliation></author><author><name sortKey="Peters, Ulrike" sort="Peters, Ulrike" uniqKey="Peters U" first="Ulrike" last="Peters">Ulrike Peters</name><affiliation><nlm:aff id="A49">Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.</nlm:aff></affiliation></author><author><name sortKey="Power, Chris" sort="Power, Chris" uniqKey="Power C" first="Chris" last="Power">Chris Power</name><affiliation><nlm:aff id="A257">Population, Policy, and Practice, University College London Institute of Child Health, London WC1N 1EH, UK.</nlm:aff></affiliation></author><author><name sortKey="Quertermous, Thomas" sort="Quertermous, Thomas" uniqKey="Quertermous T" first="Thomas" last="Quertermous">Thomas Quertermous</name><affiliation><nlm:aff id="A309">Department of Medicine, Stanford University School of Medicine, Palo Alto, California 94304, USA.</nlm:aff></affiliation></author><author><name sortKey="Rauramaa, Rainer" sort="Rauramaa, Rainer" uniqKey="Rauramaa R" first="Rainer" last="Rauramaa">Rainer Rauramaa</name><affiliation><nlm:aff id="A125">Kuopio Research Institute of Exercise Medicine, 70100 Kuopio, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A273">Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital and University of Eastern Finland, FI-70210 Kuopio, Finland.</nlm:aff></affiliation></author><author><name sortKey="Rivadeneira, Fernando" sort="Rivadeneira, Fernando" uniqKey="Rivadeneira F" first="Fernando" last="Rivadeneira">Fernando Rivadeneira</name><affiliation><nlm:aff id="A58">Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A59">Department of Epidemiology, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A60">Department of Internal Medicine, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Saaristo, Timo E" sort="Saaristo, Timo E" uniqKey="Saaristo T" first="Timo E." last="Saaristo">Timo E. Saaristo</name><affiliation><nlm:aff id="A321">Finnish Diabetes Association, Kirjoniementie 15, FI-33680 Tampere, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A322">Pirkanmaa Hospital District, FI-33521 Tampere, Finland.</nlm:aff></affiliation></author><author><name sortKey="Saleheen, Danish" sort="Saleheen, Danish" uniqKey="Saleheen D" first="Danish" last="Saleheen">Danish Saleheen</name><affiliation><nlm:aff id="A232">Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A323">Center for Non-Communicable Diseases, Karatchi, Pakistan.</nlm:aff></affiliation><affiliation><nlm:aff id="A324">Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.</nlm:aff></affiliation></author><author><name sortKey="Sattar, Naveed" sort="Sattar, Naveed" uniqKey="Sattar N" first="Naveed" last="Sattar">Naveed Sattar</name><affiliation><nlm:aff id="A325">BHF Glasgow Cardiovascular Research Centre, Division of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G12 8TA, UK.</nlm:aff></affiliation></author><author><name sortKey="Schadt, Eric E" sort="Schadt, Eric E" uniqKey="Schadt E" first="Eric E." last="Schadt">Eric E. Schadt</name><affiliation><nlm:aff id="A326">Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10580, USA.</nlm:aff></affiliation></author><author><name sortKey="Schlessinger, David" sort="Schlessinger, David" uniqKey="Schlessinger D" first="David" last="Schlessinger">David Schlessinger</name><affiliation><nlm:aff id="A155">Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland 21224, USA.</nlm:aff></affiliation></author><author><name sortKey="Slagboom, P Eline" sort="Slagboom, P Eline" uniqKey="Slagboom P" first="P. Eline" last="Slagboom">P. Eline Slagboom</name><affiliation><nlm:aff id="A34">Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A35">Department of Molecular Epidemiology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Snieder, Harold" sort="Snieder, Harold" uniqKey="Snieder H" first="Harold" last="Snieder">Harold Snieder</name><affiliation><nlm:aff id="A169">Department of Epidemiology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Spector, Tim D" sort="Spector, Tim D" uniqKey="Spector T" first="Tim D." last="Spector">Tim D. Spector</name><affiliation><nlm:aff id="A56">Department of Twin Research and Genetic Epidemiology, King’s College London, London SE1 7EH, UK.</nlm:aff></affiliation></author><author><name sortKey="Thorsteinsdottir, Unnur" sort="Thorsteinsdottir, Unnur" uniqKey="Thorsteinsdottir U" first="Unnur" last="Thorsteinsdottir">Unnur Thorsteinsdottir</name><affiliation><nlm:aff id="A171">deCODE Genetics, Amgen Inc., Reykjavik 101, Iceland.</nlm:aff></affiliation><affiliation><nlm:aff id="A327">Faculty of Medicine, University of Iceland, Reykjavik 101, Iceland.</nlm:aff></affiliation></author><author><name sortKey="Stumvoll, Michael" sort="Stumvoll, Michael" uniqKey="Stumvoll M" first="Michael" last="Stumvoll">Michael Stumvoll</name><affiliation><nlm:aff id="A96">Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, D-04103 Leipzig, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A97">Department of Medicine, University of Leipzig, D-04103 Leipzig, Germany.</nlm:aff></affiliation></author><author><name sortKey="Tuomilehto, Jaakko" sort="Tuomilehto, Jaakko" uniqKey="Tuomilehto J" first="Jaakko" last="Tuomilehto">Jaakko Tuomilehto</name><affiliation><nlm:aff id="A53">National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A328">Institute for Health Research, University Hospital of La Paz (IdiPaz), 28046 Madrid, Spain.</nlm:aff></affiliation><affiliation><nlm:aff id="A329">Diabetes Research Group, King Abdulaziz University, 21589 Jeddah, Saudi Arabia.</nlm:aff></affiliation><affiliation><nlm:aff id="A330">Centre for Vascular Prevention, Danube-University Krems, 3500 Krems, Austria.</nlm:aff></affiliation></author><author><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="André G." last="Uitterlinden">André G. Uitterlinden</name><affiliation><nlm:aff id="A58">Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A59">Department of Epidemiology, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A60">Department of Internal Medicine, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Uusitupa, Matti" sort="Uusitupa, Matti" uniqKey="Uusitupa M" first="Matti" last="Uusitupa">Matti Uusitupa</name><affiliation><nlm:aff id="A331">Department of Public Health and Clinical Nutrition, University of Eastern Finland, Finland.</nlm:aff></affiliation><affiliation><nlm:aff id="A332">Research Unit, Kuopio University Hospital, FI-70210 Kuopio, Finland.</nlm:aff></affiliation></author><author><name sortKey="Van Der Harst, Pim" sort="Van Der Harst, Pim" uniqKey="Van Der Harst P" first="Pim" last="Van Der Harst">Pim Van Der Harst</name><affiliation><nlm:aff id="A29">Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A57">Department of Cardiology, University Medical Center Groningen, University of Groningen, 9700RB Groningen, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A264">Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands (ICIN), 3501 DG Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Walker, Mark" sort="Walker, Mark" uniqKey="Walker M" first="Mark" last="Walker">Mark Walker</name><affiliation><nlm:aff id="A333">Institute of Cellular Medicine, Newcastle University, Newcastle NE1 7RU, UK.</nlm:aff></affiliation></author><author><name sortKey="Wallaschofski, Henri" sort="Wallaschofski, Henri" uniqKey="Wallaschofski H" first="Henri" last="Wallaschofski">Henri Wallaschofski</name><affiliation><nlm:aff id="A239">DZHK (Deutsches Zentrum für Herz-Kreislaufforschung – German Centre for Cardiovascular Research), partner site Greifswald, D-17475 Greifswald, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A334">Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, D-17475 Greifswald, Germany.</nlm:aff></affiliation></author><author><name sortKey="Wareham, Nicholas J" sort="Wareham, Nicholas J" uniqKey="Wareham N" first="Nicholas J." last="Wareham">Nicholas J. Wareham</name><affiliation><nlm:aff id="A9">MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:aff></affiliation></author><author><name sortKey="Watkins, Hugh" sort="Watkins, Hugh" uniqKey="Watkins H" first="Hugh" last="Watkins">Hugh Watkins</name><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A48">Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, UK.</nlm:aff></affiliation></author><author><name sortKey="Weir, David R" sort="Weir, David R" uniqKey="Weir D" first="David R." last="Weir">David R. Weir</name><affiliation><nlm:aff id="A26">Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan 48104, USA.</nlm:aff></affiliation></author><author><name sortKey="Wichmann, H Erich" sort="Wichmann, H Erich" uniqKey="Wichmann H" first="H-Erich" last="Wichmann">H-Erich Wichmann</name><affiliation><nlm:aff id="A335">Institute of Medical Informatics, Biometry and Epidemiology, Chair of Epidemiology, Ludwig-Maximilians-Universität, D-85764 Munich, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A336">Klinikum Grosshadern, D-81377 Munich, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A337">Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany, D-85764 Neuherberg, Germany.</nlm:aff></affiliation></author><author><name sortKey="Wilson, James F" sort="Wilson, James F" uniqKey="Wilson J" first="James F." last="Wilson">James F. Wilson</name><affiliation><nlm:aff id="A36">Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK.</nlm:aff></affiliation></author><author><name sortKey="Zanen, Pieter" sort="Zanen, Pieter" uniqKey="Zanen P" first="Pieter" last="Zanen">Pieter Zanen</name><affiliation><nlm:aff id="A338">Department of Pulmonology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Borecki, Ingrid B" sort="Borecki, Ingrid B" uniqKey="Borecki I" first="Ingrid B." last="Borecki">Ingrid B. Borecki</name><affiliation><nlm:aff id="A47">Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:aff></affiliation></author><author><name sortKey="Deloukas, Panos" sort="Deloukas, Panos" uniqKey="Deloukas P" first="Panos" last="Deloukas">Panos Deloukas</name><affiliation><nlm:aff id="A22">Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A50">William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A339">Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, 21589 Jeddah, Saudi Arabia.</nlm:aff></affiliation></author><author><name sortKey="Fox, Caroline S" sort="Fox, Caroline S" uniqKey="Fox C" first="Caroline S." last="Fox">Caroline S. Fox</name><affiliation><nlm:aff id="A127">National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts 01702, USA.</nlm:aff></affiliation></author><author><name sortKey="Heid, Iris M" sort="Heid, Iris M" uniqKey="Heid I" first="Iris M." last="Heid">Iris M. Heid</name><affiliation><nlm:aff id="A23">Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, D-93053 Regensburg, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A85">Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.</nlm:aff></affiliation></author><author><name sortKey="O Onnell, Jeffrey R" sort="O Onnell, Jeffrey R" uniqKey="O Onnell J" first="Jeffrey R." last="O Onnell">Jeffrey R. O Onnell</name><affiliation><nlm:aff id="A295">Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A296">Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.</nlm:aff></affiliation></author><author><name sortKey="Strachan, David P" sort="Strachan, David P" uniqKey="Strachan D" first="David P." last="Strachan">David P. Strachan</name><affiliation><nlm:aff id="A340">Division of Population Health Sciences & Education, St George’s, University of London, London SW17 0RE, UK.</nlm:aff></affiliation></author><author><name sortKey="Stefansson, Kari" sort="Stefansson, Kari" uniqKey="Stefansson K" first="Kari" last="Stefansson">Kari Stefansson</name><affiliation><nlm:aff id="A171">deCODE Genetics, Amgen Inc., Reykjavik 101, Iceland.</nlm:aff></affiliation><affiliation><nlm:aff id="A327">Faculty of Medicine, University of Iceland, Reykjavik 101, Iceland.</nlm:aff></affiliation></author><author><name sortKey="Van Duijn, Cornelia M" sort="Van Duijn, Cornelia M" uniqKey="Van Duijn C" first="Cornelia M." last="Van Duijn">Cornelia M. Van Duijn</name><affiliation><nlm:aff id="A32">Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC University Medical Center, 3015 GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A58">Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A59">Department of Epidemiology, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:aff></affiliation><affiliation><nlm:aff id="A84">Center for Medical Sytems Biology, 2300 RC Leiden, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Abecasis, Goncalo R" sort="Abecasis, Goncalo R" uniqKey="Abecasis G" first="Gonçalo R." last="Abecasis">Gonçalo R. Abecasis</name><affiliation><nlm:aff id="A1">Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation></author><author><name sortKey="Franke, Lude" sort="Franke, Lude" uniqKey="Franke L" first="Lude" last="Franke">Lude Franke</name><affiliation><nlm:aff id="A29">Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</nlm:aff></affiliation></author><author><name sortKey="Frayling, Timothy M" sort="Frayling, Timothy M" uniqKey="Frayling T" first="Timothy M." last="Frayling">Timothy M. Frayling</name><affiliation><nlm:aff id="A24">Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK.</nlm:aff></affiliation></author><author><name sortKey="Mccarthy, Mark I" sort="Mccarthy, Mark I" uniqKey="Mccarthy M" first="Mark I." last="Mccarthy">Mark I. Mccarthy</name><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A64">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A341">Oxford NIHR Biomedical Research Centre, Oxford University Hospitals NHS Trust, Oxford OX3 7LJ, UK.</nlm:aff></affiliation></author><author><name sortKey="Visscher, Peter M" sort="Visscher, Peter M" uniqKey="Visscher P" first="Peter M." last="Visscher">Peter M. Visscher</name><affiliation><nlm:aff id="A11">Queensland Brain Institute, The University of Queensland, Brisbane 4072, Australia.</nlm:aff></affiliation><affiliation><nlm:aff id="A12">The University of Queensland Diamantina Institute, The Translation Research Institute, Brisbane 4012, Australia.</nlm:aff></affiliation></author><author><name sortKey="Scherag, Andre" sort="Scherag, Andre" uniqKey="Scherag A" first="André" last="Scherag">André Scherag</name><affiliation><nlm:aff id="A63">Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen, 45147 Essen, Germany.</nlm:aff></affiliation><affiliation><nlm:aff id="A342">Clinical Epidemiology, Integrated Research and Treatment Center, Center for Sepsis Control and Care (CSCC), Jena University Hospital, 07743 Jena, Germany.</nlm:aff></affiliation></author><author><name sortKey="Willer, Cristen J" sort="Willer, Cristen J" uniqKey="Willer C" first="Cristen J." last="Willer">Cristen J. Willer</name><affiliation><nlm:aff id="A28">Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A30">Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A343">Department of Human Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation></author><author><name sortKey="Boehnke, Michael" sort="Boehnke, Michael" uniqKey="Boehnke M" first="Michael" last="Boehnke">Michael Boehnke</name><affiliation><nlm:aff id="A1">Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation></author><author><name sortKey="Mohlke, Karen L" sort="Mohlke, Karen L" uniqKey="Mohlke K" first="Karen L." last="Mohlke">Karen L. Mohlke</name><affiliation><nlm:aff id="A10">Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.</nlm:aff></affiliation></author><author><name sortKey="Lindgren, Cecilia M" sort="Lindgren, Cecilia M" uniqKey="Lindgren C" first="Cecilia M." last="Lindgren">Cecilia M. Lindgren</name><affiliation><nlm:aff id="A6">Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation></author><author><name sortKey="Beckmann, Jacques S" sort="Beckmann, Jacques S" uniqKey="Beckmann J" first="Jacques S." last="Beckmann">Jacques S. Beckmann</name><affiliation><nlm:aff id="A20">Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland.</nlm:aff></affiliation><affiliation><nlm:aff id="A21">Department of Medical Genetics, University of Lausanne, Lausanne 1005, Switzerland.</nlm:aff></affiliation><affiliation><nlm:aff id="A344">Service of Medical Genetics, CHUV University Hospital, 1011 Lausanne, Switzerland.</nlm:aff></affiliation></author><author><name sortKey="Barroso, Ines" sort="Barroso, Ines" uniqKey="Barroso I" first="Inês" last="Barroso">Inês Barroso</name><affiliation><nlm:aff id="A22">Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A345">University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge CB2 OQQ, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A346">NIHR Cambridge Biomedical Research Centre, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge CB2 OQQ, UK.</nlm:aff></affiliation></author><author><name sortKey="North, Kari E" sort="North, Kari E" uniqKey="North K" first="Kari E." last="North">Kari E. North</name><affiliation><nlm:aff id="A4">Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A347">Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.</nlm:aff></affiliation></author><author><name sortKey="Ingelsson, Erik" sort="Ingelsson, Erik" uniqKey="Ingelsson E" first="Erik" last="Ingelsson">Erik Ingelsson</name><affiliation><nlm:aff id="A16">Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.</nlm:aff></affiliation><affiliation><nlm:aff id="A17">Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala 75185, Sweden.</nlm:aff></affiliation><affiliation><nlm:aff id="A18">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:aff></affiliation></author><author><name sortKey="Hirschhorn, Joel N" sort="Hirschhorn, Joel N" uniqKey="Hirschhorn J" first="Joel N." last="Hirschhorn">Joel N. Hirschhorn</name><affiliation><nlm:aff id="A5">Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children’s Hospital, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A6">Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A7">Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.</nlm:aff></affiliation></author><author><name sortKey="Loos, Ruth J F" sort="Loos, Ruth J F" uniqKey="Loos R" first="Ruth J. F." last="Loos">Ruth J. F. Loos</name><affiliation><nlm:aff id="A9">MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:aff></affiliation><affiliation><nlm:aff id="A55">The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A145">The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:aff></affiliation><affiliation><nlm:aff id="A348">The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:aff></affiliation></author><author><name sortKey="Speliotes, Elizabeth K" sort="Speliotes, Elizabeth K" uniqKey="Speliotes E" first="Elizabeth K." last="Speliotes">Elizabeth K. Speliotes</name><affiliation><nlm:aff id="A2">Department of Internal Medicine, Division of Gastroenterology, and Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:aff></affiliation></author></analytic><series><title level="j">Nature</title><idno type="ISSN">0028-0836</idno><idno type="eISSN">1476-4687</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P4">Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity better, here we conduct a genome-wide association study and Metabochip meta-analysis of body mass index (BMI), a measure commonly used to define obesity and assess adiposity, in up to 339,224 individuals. This analysis identifies 97 BMI-associated loci (<italic>P</italic> < 5 × 10<sup>−8</sup>), 56 of which are novel. Five loci demonstrate clear evidence of several independent association signals, and many loci have significant effects on other metabolic phenotypes. The 97 loci account for ~2.7% of BMI variation, and genome-wide estimates suggest that common variation accounts for >20% of BMI variation. Pathway analyses provide strong support for a role of the central nervous system in obesity susceptibility and implicate new genes and pathways, including those related to synaptic function, glutamate signalling, insulin secretion/action, energy metabolism, lipid biology and adipogenesis.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">0410462</journal-id><journal-id journal-id-type="pubmed-jr-id">6011</journal-id><journal-id journal-id-type="nlm-ta">Nature</journal-id><journal-id journal-id-type="iso-abbrev">Nature</journal-id><journal-title-group><journal-title>Nature</journal-title></journal-title-group><issn pub-type="ppub">0028-0836</issn><issn pub-type="epub">1476-4687</issn></journal-meta><article-meta><article-id pub-id-type="pmid">25673413</article-id><article-id pub-id-type="pmc">4382211</article-id><article-id pub-id-type="doi">10.1038/nature14177</article-id><article-id pub-id-type="manuscript">NIHMS668049</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Genetic studies of body mass index yield new insights for obesity biology</article-title></title-group><contrib-group><contrib contrib-type="author" 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rid="A328">328</xref><xref ref-type="aff" rid="A329">329</xref><xref ref-type="aff" rid="A330">330</xref></contrib><contrib contrib-type="author"><name><surname>Uitterlinden</surname><given-names>André G.</given-names></name><xref ref-type="aff" rid="A58">58</xref><xref ref-type="aff" rid="A59">59</xref><xref ref-type="aff" rid="A60">60</xref></contrib><contrib contrib-type="author"><name><surname>Uusitupa</surname><given-names>Matti</given-names></name><xref ref-type="aff" rid="A331">331</xref><xref ref-type="aff" rid="A332">332</xref></contrib><contrib contrib-type="author"><name><surname>van der Harst</surname><given-names>Pim</given-names></name><xref ref-type="aff" rid="A29">29</xref><xref ref-type="aff" rid="A57">57</xref><xref ref-type="aff" rid="A264">264</xref></contrib><contrib contrib-type="author"><name><surname>Walker</surname><given-names>Mark</given-names></name><xref ref-type="aff" rid="A333">333</xref></contrib><contrib contrib-type="author"><name><surname>Wallaschofski</surname><given-names>Henri</given-names></name><xref ref-type="aff" rid="A239">239</xref><xref ref-type="aff" rid="A334">334</xref></contrib><contrib contrib-type="author"><name><surname>Wareham</surname><given-names>Nicholas J.</given-names></name><xref ref-type="aff" rid="A9">9</xref></contrib><contrib contrib-type="author"><name><surname>Watkins</surname><given-names>Hugh</given-names></name><xref ref-type="aff" rid="A18">18</xref><xref ref-type="aff" rid="A48">48</xref></contrib><contrib contrib-type="author"><name><surname>Weir</surname><given-names>David R.</given-names></name><xref ref-type="aff" rid="A26">26</xref></contrib><contrib contrib-type="author"><name><surname>Wichmann</surname><given-names>H-Erich</given-names></name><xref ref-type="aff" rid="A335">335</xref><xref ref-type="aff" rid="A336">336</xref><xref ref-type="aff" rid="A337">337</xref></contrib><contrib contrib-type="author"><name><surname>Wilson</surname><given-names>James F.</given-names></name><xref ref-type="aff" rid="A36">36</xref></contrib><contrib contrib-type="author"><name><surname>Zanen</surname><given-names>Pieter</given-names></name><xref ref-type="aff" rid="A338">338</xref></contrib><contrib contrib-type="author"><name><surname>Borecki</surname><given-names>Ingrid B.</given-names></name><xref ref-type="aff" rid="A47">47</xref></contrib><contrib contrib-type="author"><name><surname>Deloukas</surname><given-names>Panos</given-names></name><xref ref-type="aff" rid="A22">22</xref><xref ref-type="aff" rid="A50">50</xref><xref ref-type="aff" rid="A339">339</xref></contrib><contrib contrib-type="author"><name><surname>Fox</surname><given-names>Caroline S.</given-names></name><xref ref-type="aff" rid="A127">127</xref></contrib><contrib contrib-type="author"><name><surname>Heid</surname><given-names>Iris M.</given-names></name><xref ref-type="aff" rid="A23">23</xref><xref 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ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Franke</surname><given-names>Lude</given-names></name><xref ref-type="aff" rid="A29">29</xref></contrib><contrib contrib-type="author"><name><surname>Frayling</surname><given-names>Timothy M.</given-names></name><xref ref-type="aff" rid="A24">24</xref></contrib><contrib contrib-type="author"><name><surname>McCarthy</surname><given-names>Mark I.</given-names></name><xref ref-type="aff" rid="A18">18</xref><xref ref-type="aff" rid="A64">64</xref><xref ref-type="aff" rid="A341">341</xref></contrib><contrib contrib-type="author"><name><surname>Visscher</surname><given-names>Peter M.</given-names></name><xref ref-type="aff" rid="A11">11</xref><xref ref-type="aff" rid="A12">12</xref></contrib><contrib contrib-type="author"><name><surname>Scherag</surname><given-names>André</given-names></name><xref ref-type="aff" rid="A63">63</xref><xref ref-type="aff" rid="A342">342</xref></contrib><contrib contrib-type="author"><name><surname>Willer</surname><given-names>Cristen J.</given-names></name><xref ref-type="aff" rid="A28">28</xref><xref ref-type="aff" rid="A30">30</xref><xref ref-type="aff" rid="A343">343</xref></contrib><contrib contrib-type="author"><name><surname>Boehnke</surname><given-names>Michael</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Mohlke</surname><given-names>Karen L.</given-names></name><xref ref-type="aff" rid="A10">10</xref></contrib><contrib contrib-type="author"><name><surname>Lindgren</surname><given-names>Cecilia M.</given-names></name><xref ref-type="aff" rid="A6">6</xref><xref ref-type="aff" rid="A18">18</xref></contrib><contrib contrib-type="author"><name><surname>Beckmann</surname><given-names>Jacques S.</given-names></name><xref ref-type="aff" rid="A20">20</xref><xref ref-type="aff" rid="A21">21</xref><xref ref-type="aff" rid="A344">344</xref></contrib><contrib contrib-type="author"><name><surname>Barroso</surname><given-names>Inês</given-names></name><xref ref-type="aff" rid="A22">22</xref><xref ref-type="aff" rid="A345">345</xref><xref ref-type="aff" rid="A346">346</xref></contrib><contrib contrib-type="author"><name><surname>North</surname><given-names>Kari E.</given-names></name><xref ref-type="aff" rid="A4">4</xref><xref ref-type="aff" rid="A347">347</xref><xref ref-type="author-notes" rid="FN3">§</xref></contrib><contrib contrib-type="author"><name><surname>Ingelsson</surname><given-names>Erik</given-names></name><xref ref-type="aff" rid="A16">16</xref><xref ref-type="aff" rid="A17">17</xref><xref ref-type="aff" rid="A18">18</xref><xref ref-type="author-notes" rid="FN3">§</xref></contrib><contrib contrib-type="author"><name><surname>Hirschhorn</surname><given-names>Joel N.</given-names></name><xref ref-type="aff" rid="A5">5</xref><xref ref-type="aff" rid="A6">6</xref><xref ref-type="aff" rid="A7">7</xref><xref ref-type="author-notes" rid="FN3">§</xref></contrib><contrib contrib-type="author"><name><surname>Loos</surname><given-names>Ruth J. F.</given-names></name><xref ref-type="aff" rid="A9">9</xref><xref ref-type="aff" rid="A55">55</xref><xref ref-type="aff" rid="A145">145</xref><xref ref-type="aff" rid="A348">348</xref><xref ref-type="author-notes" rid="FN3">§</xref></contrib><contrib contrib-type="author"><name><surname>Speliotes</surname><given-names>Elizabeth K.</given-names></name><xref ref-type="aff" rid="A2">2</xref><xref ref-type="author-notes" rid="FN3">§</xref></contrib></contrib-group><aff id="A1"><label>1</label>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.</aff><aff id="A2"><label>2</label>Department of Internal Medicine, Division of Gastroenterology, and Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.</aff><aff id="A3"><label>3</label>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.</aff><aff id="A4"><label>4</label>Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.</aff><aff id="A5"><label>5</label>Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children’s Hospital, Boston, Massachusetts 02115, USA.</aff><aff id="A6"><label>6</label>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.</aff><aff id="A7"><label>7</label>Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.</aff><aff id="A8"><label>8</label>Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby 2800, Denmark.</aff><aff id="A9"><label>9</label>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</aff><aff id="A10"><label>10</label>Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.</aff><aff id="A11"><label>11</label>Queensland Brain Institute, The University of Queensland, Brisbane 4072, Australia.</aff><aff id="A12"><label>12</label>The University of Queensland Diamantina Institute, The Translation Research Institute, Brisbane 4012, Australia.</aff><aff id="A13"><label>13</label>Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.</aff><aff id="A14"><label>14</label>Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.</aff><aff id="A15"><label>15</label>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden.</aff><aff id="A16"><label>16</label>Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.</aff><aff id="A17"><label>17</label>Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala 75185, Sweden.</aff><aff id="A18"><label>18</label>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</aff><aff id="A19"><label>19</label>Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne 1010, Switzerland.</aff><aff id="A20"><label>20</label>Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland.</aff><aff id="A21"><label>21</label>Department of Medical Genetics, University of Lausanne, Lausanne 1005, Switzerland.</aff><aff id="A22"><label>22</label>Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.</aff><aff id="A23"><label>23</label>Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, D-93053 Regensburg, Germany.</aff><aff id="A24"><label>24</label>Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK.</aff><aff id="A25"><label>25</label>Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA.</aff><aff id="A26"><label>26</label>Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan 48104, USA.</aff><aff id="A27"><label>27</label>Department of Epidemiology, University of Michigan, Ann Arbor, Michigan 48109, USA.</aff><aff id="A28"><label>28</label>Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA.</aff><aff id="A29"><label>29</label>Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</aff><aff id="A30"><label>30</label>Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.</aff><aff id="A31"><label>31</label>HudsonAlpha Institute for Biotechnology, Huntsville, Alabama 35806, USA.</aff><aff id="A32"><label>32</label>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC University Medical Center, 3015 GE Rotterdam, The Netherlands.</aff><aff id="A33"><label>33</label>Telethon Institute for Child Health Research, Centre for Child Health Research, The University of Western Australia, Perth, Western Australia 6008, Australia.</aff><aff id="A34"><label>34</label>Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.</aff><aff id="A35"><label>35</label>Department of Molecular Epidemiology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.</aff><aff id="A36"><label>36</label>Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK.</aff><aff id="A37"><label>37</label>Kidney Epidemiology and Cost Center, University of Michigan, Ann Arbor, Michigan 48109, USA.</aff><aff id="A38"><label>38</label>Department of Statistics & Biostatistics, Rutgers University, Piscataway, New Jersey 08854, USA.</aff><aff id="A39"><label>39</label>Department of Genetics, Rutgers University, Piscataway, New Jersey 08854, USA.</aff><aff id="A40"><label>40</label>Department of Human Genetics, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.</aff><aff id="A41"><label>41</label>Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.</aff><aff id="A42"><label>42</label>Department of Gastroenterology and Hepatology, Imperial College London, London W2 1PG, UK.</aff><aff id="A43"><label>43</label>Institute of infectious Diseases, Southwest Hospital, Third Military Medical University, Chongqing, China.</aff><aff id="A44"><label>44</label>Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.</aff><aff id="A45"><label>45</label>Cardiology, Department of Specialties of Internal Medicine, Geneva University Hospital, Geneva 1211, Switzerland.</aff><aff id="A46"><label>46</label>Department of Epidemiology Research, Statens Serum Institut, Copenhagen DK-2300, Denmark.</aff><aff id="A47"><label>47</label>Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63110, USA.</aff><aff id="A48"><label>48</label>Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, UK.</aff><aff id="A49"><label>49</label>Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.</aff><aff id="A50"><label>50</label>William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.</aff><aff id="A51"><label>51</label>Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, D-68187 Mannheim, Germany.</aff><aff id="A52"><label>52</label>Department of Internal Medicine II, Ulm University Medical Centre, D-89081 Ulm, Germany.</aff><aff id="A53"><label>53</label>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</aff><aff id="A54"><label>54</label>Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96813, USA.</aff><aff id="A55"><label>55</label>The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</aff><aff id="A56"><label>56</label>Department of Twin Research and Genetic Epidemiology, King’s College London, London SE1 7EH, UK.</aff><aff id="A57"><label>57</label>Department of Cardiology, University Medical Center Groningen, University of Groningen, 9700RB Groningen, The Netherlands.</aff><aff id="A58"><label>58</label>Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.</aff><aff id="A59"><label>59</label>Department of Epidemiology, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.</aff><aff id="A60"><label>60</label>Department of Internal Medicine, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.</aff><aff id="A61"><label>61</label>QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4006, Australia.</aff><aff id="A62"><label>62</label>Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892, USA.</aff><aff id="A63"><label>63</label>Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen, 45147 Essen, Germany.</aff><aff id="A64"><label>64</label>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.</aff><aff id="A65"><label>65</label>Department of Genomics of Common Disease, School of Public Health, Imperial College London, Hammersmith Hospital, London W12 0NN, UK.</aff><aff id="A66"><label>66</label>Department of Clinical Sciences, Genetic & Molecular Epidemiology Unit, Lund University Diabetes Center, Skåne University Hosptial, Malmö 205 02, Sweden.</aff><aff id="A67"><label>67</label>Department of Public Health and Clinical Medicine, Unit of Medicine, Umeå University, Umeå 901 87, Sweden.</aff><aff id="A68"><label>68</label>Department of Odontology, Umeå University, Umeå 901 85, Sweden.</aff><aff id="A69"><label>69</label>University of Eastern Finland, FI-70210 Kuopio, Finland.</aff><aff id="A70"><label>70</label>Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm 17176, Sweden.</aff><aff id="A71"><label>71</label>Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri 63110, USA.</aff><aff id="A72"><label>72</label>Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland 21225, USA.</aff><aff id="A73"><label>73</label>Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, D-17475 Greifswald, Germany.</aff><aff id="A74"><label>74</label>Department of Cardiology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.</aff><aff id="A75"><label>75</label>Department of Gerontology and Geriatrics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.</aff><aff id="A76"><label>76</label>Experimental Cardiology Laboratory, Division Heart and Lungs, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.</aff><aff id="A77"><label>77</label>Department of Medical Genetics, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.</aff><aff id="A78"><label>78</label>Department of Endocrinology, University of Groningen, University Medical Center Groningen, 9700 RB Groningen, The Netherlands.</aff><aff id="A79"><label>79</label>Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland 21702, USA.</aff><aff id="A80"><label>80</label>CNRS UMR 8199, F-59019 Lille, France.</aff><aff id="A81"><label>81</label>European Genomic Institute for Diabetes, F-59000 Lille, France.</aff><aff id="A82"><label>82</label>Université de Lille 2, F-59000 Lille, France.</aff><aff id="A83"><label>83</label>Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.</aff><aff id="A84"><label>84</label>Center for Medical Sytems Biology, 2300 RC Leiden, The Netherlands.</aff><aff id="A85"><label>85</label>Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.</aff><aff id="A86"><label>86</label>School of Health and Social Studies, Dalarna University, SE-791 88 Falun, Sweden.</aff><aff id="A87"><label>87</label>PathWest Laboratory Medicine of Western Australia, Nedlands, Western Australia 6009, Australia.</aff><aff id="A88"><label>88</label>Department of Haematology, University of Cambridge, Cambridge CB2 0PT, UK.</aff><aff id="A89"><label>89</label>NHS Blood and Transplant, Cambridge CB2 0PT, UK.</aff><aff id="A90"><label>90</label>Geriatric Unit, Azienda Sanitaria Firenze (ASF), 50125 Florence, Italy.</aff><aff id="A91"><label>91</label>USC-Office of Population Studies Foundation, Inc., University of San Carlos, Cebu City 6000, Philippines.</aff><aff id="A92"><label>92</label>Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas 78227, USA.</aff><aff id="A93"><label>93</label>Genomics Research Centre, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland 4001, Australia.</aff><aff id="A94"><label>94</label>Department of Medical Sciences, Endocrinology, Diabetes and Metabolism, Uppsala University, Uppsala 75185, Sweden.</aff><aff id="A95"><label>95</label>Division of Endocrinology, Diabetes and Metabolism, Ulm University Medical Centre, D-89081 Ulm, Germany.</aff><aff id="A96"><label>96</label>Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, D-04103 Leipzig, Germany.</aff><aff id="A97"><label>97</label>Department of Medicine, University of Leipzig, D-04103 Leipzig, Germany.</aff><aff id="A98"><label>98</label>Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.</aff><aff id="A99"><label>99</label>Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA.</aff><aff id="A100"><label>100</label>LifeLines Cohort Study, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</aff><aff id="A101"><label>101</label>Department of Biology, Norwegian University of Science and Technology, 7491 Trondheim, Norway.</aff><aff id="A102"><label>102</label>Department of Pediatrics, University of California Los Angeles, Torrance, California 90502, USA.</aff><aff id="A103"><label>103</label>Transgenomics Institute, Los Angeles Biomedical Research Institute, Torrance, California 90502, USA.</aff><aff id="A104"><label>104</label>Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.</aff><aff id="A105"><label>105</label>Department of Dietetics-Nutrition, Harokopio University, 17671 Athens, Greece.</aff><aff id="A106"><label>106</label>Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.</aff><aff id="A107"><label>107</label>Institute for Molecular Medicine, University of Helsinki, FI-00014 Helsinki, Finland.</aff><aff id="A108"><label>108</label>Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA.</aff><aff id="A109"><label>109</label>Laboratory of Epidemiology and Population Sciences, National Institute on Aging, NIH, Bethesda, Maryland 20892, USA.</aff><aff id="A110"><label>110</label>Department of Public Health and Caring Sciences, Geriatrics, Uppsala University, Uppsala 75185, Sweden.</aff><aff id="A111"><label>111</label>Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, Stockholm 17177, Sweden.</aff><aff id="A112"><label>112</label>Kaiser Permanente, Division of Research, Oakland, California 94612, USA.</aff><aff id="A113"><label>113</label>Service of Therapeutic Education for Diabetes, Obesity and Chronic Diseases, Geneva University Hospital, Geneva CH-1211, Switzerland.</aff><aff id="A114"><label>114</label>Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester LE3 9QP, UK.</aff><aff id="A115"><label>115</label>National Institute for Health Research (NIHR) Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester LE3 9QP, UK.</aff><aff id="A116"><label>116</label>Department of Nephrology, University Hospital Regensburg, D-93053 Regensburg, Germany.</aff><aff id="A117"><label>117</label>Department of Psychiatry and Psychotherapy, University Medicine Greifswald, HELIOS-Hospital Stralsund, D-17475 Greifswald, Germany.</aff><aff id="A118"><label>118</label>German Center for Neurodegenerative Diseases (DZNE), Rostock, Greifswald, D-17475 Greifswald, Germany.</aff><aff id="A119"><label>119</label>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.</aff><aff id="A120"><label>120</label>German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany.</aff><aff id="A121"><label>121</label>Department of Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, D-01307 Dresden, Germany.</aff><aff id="A122"><label>122</label>Institut inter Régional pour la Santé, Synergies, F-37520 La Riche, France.</aff><aff id="A123"><label>123</label>Department of Public Health and Clinical Medicine, Unit of Nutritional Research, Umeå University, Umeå 90187, Sweden.</aff><aff id="A124"><label>124</label>Department of Psychiatry, University of Groningen, University Medical Center Groningen, 9700RB Groningen, The Netherlands.</aff><aff id="A125"><label>125</label>Kuopio Research Institute of Exercise Medicine, 70100 Kuopio, Finland.</aff><aff id="A126"><label>126</label>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK.</aff><aff id="A127"><label>127</label>National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts 01702, USA.</aff><aff id="A128"><label>128</label>Department of Neurology, Boston University School of Medicine, Boston, Massachusetts 02118, USA.</aff><aff id="A129"><label>129</label>Faculty of Psychology and Education, VU University Amsterdam, 1081BT Amsterdam, The Netherlands.</aff><aff id="A130"><label>130</label>Deutsches Forschungszentrum für Herz-Kreislauferkrankungen (DZHK) (German Research Centre for Cardiovascular Research), Munich Heart Alliance, D-80636 Munich, Germany.</aff><aff id="A131"><label>131</label>Deutsches Herzzentrum München, Technische Universität München, D-80636 Munich, Germany.</aff><aff id="A132"><label>132</label>Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim 7489, Norway.</aff><aff id="A133"><label>133</label>Biological Psychology, VU University Amsterdam, 1081BT Amsterdam, The Netherlands.</aff><aff id="A134"><label>134</label>Department of Pulmonary Physiology and Sleep Medicine, Nedlands, Western Australia 6009, Australia.</aff><aff id="A135"><label>135</label>School of Medicine and Pharmacology, University of Western Australia, Crawley 6009, Australia.</aff><aff id="A136"><label>136</label>Uppsala University, Department of Immunology, Genetics, Pathology, SciLifeLab, Rudbeck Laboratory, SE-751 85 Uppsala, Sweden.</aff><aff id="A137"><label>137</label>Hjelt Institute Department of Public Health, University of Helsinki, FI-00014 Helsinki, Finland.</aff><aff id="A138"><label>138</label>Department of Internal Medicine I, Ulm University Medical Centre, D-89081 Ulm, Germany.</aff><aff id="A139"><label>139</label>Finnish Institute of Occupational Health, FI-90100 Oulu, Finland.</aff><aff id="A140"><label>140</label>Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, 6020 Innsbruck, Austria.</aff><aff id="A141"><label>141</label>Institute of Human Genetics, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.</aff><aff id="A142"><label>142</label>Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala 75185, Sweden.</aff><aff id="A143"><label>143</label>Montreal Heart Institute, Montreal, Quebec H1T 1C8, Canada.</aff><aff id="A144"><label>144</label>Institute for Community Medicine, University Medicine Greifswald, D-17475 Greifswald, Germany.</aff><aff id="A145"><label>145</label>The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</aff><aff id="A146"><label>146</label>School of Social and Community Medicine, University of Bristol, Bristol BS8 2BN, UK.</aff><aff id="A147"><label>147</label>Institute of Molecular and Cell Biology, University of Tartu, Tartu 51010, Estonia.</aff><aff id="A148"><label>148</label>Farr Institute of Health Informatics Research, University College London, London NW1 2DA, UK.</aff><aff id="A149"><label>149</label>The Center for Observational Research, Amgen, Inc., Thousand Oaks, California 91320, USA.</aff><aff id="A150"><label>150</label>Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche, Cagliari, Sardinia 09042, Italy.</aff><aff id="A151"><label>151</label>Center for Evidence-based Healthcare, University Hospital Carl Gustav Carus, Technische Universität Dresden, D-01307 Dresden, Germany.</aff><aff id="A152"><label>152</label>Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität, D-81377 Munich, Germany.</aff><aff id="A153"><label>153</label>Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, D-81377 Munich, Germany.</aff><aff id="A154"><label>154</label>Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia 6009, Australia.</aff><aff id="A155"><label>155</label>Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland 21224, USA.</aff><aff id="A156"><label>156</label>Department of Genomics, Life & Brain Center, University of Bonn, 53127 Bonn, Germany.</aff><aff id="A157"><label>157</label>Institute of Human Genetics, University of Bonn, 53127 Bonn, Germany.</aff><aff id="A158"><label>158</label>Department of Epidemiology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</aff><aff id="A159"><label>159</label>Department of Epidemiology and Biostatistics, Institute for Research in Extramural Medicine, Institute for Health and Care Research, VU University Medical Center, 1081BT Amsterdam, The Netherlands.</aff><aff id="A160"><label>160</label>Department of Internal Medicine, Division of Endocrinology and Metabolism, Medical University of Graz, 8036 Graz, Austria.</aff><aff id="A161"><label>161</label>Institute of Physiology, University Medicine Greifswald, D-17495 Karlsburg, Germany.</aff><aff id="A162"><label>162</label>Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.</aff><aff id="A163"><label>163</label>Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, Massachusetts 02215, USA.</aff><aff id="A164"><label>164</label>Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz 8036, Austria.</aff><aff id="A165"><label>165</label>Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA.</aff><aff id="A166"><label>166</label>National Cancer Institute, Bethesda, Maryland 20892, USA.</aff><aff id="A167"><label>167</label>Icelandic Heart Association, Kopavogur 201, Iceland.</aff><aff id="A168"><label>168</label>University of Iceland, Reykjavik 101, Iceland.</aff><aff id="A169"><label>169</label>Department of Epidemiology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</aff><aff id="A170"><label>170</label>Molecular & Cellular Therapeutics, Royal College of Surgeons in Ireland, 123 St Stephen’s Green, Dublin 2, Ireland.</aff><aff id="A171"><label>171</label>deCODE Genetics, Amgen Inc., Reykjavik 101, Iceland.</aff><aff id="A172"><label>172</label>Department of Medical Sciences, Molecular Medicine, Uppsala University, Uppsala 75144, Sweden.</aff><aff id="A173"><label>173</label>National Heart and Lung Institute, Imperial College London, London SW3 6LY, UK.</aff><aff id="A174"><label>174</label>Department of Public Health Sciences, Stritch School of Medicine, Loyola University of Chicago, Maywood, Illinois 61053, USA.</aff><aff id="A175"><label>175</label>Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany, D-85764 Neuherberg, Germany.</aff><aff id="A176"><label>176</label>Department of Oncology, University of Cambridge, Cambridge CB2 0QQ, UK.</aff><aff id="A177"><label>177</label>Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg 413 45, Sweden.</aff><aff id="A178"><label>178</label>Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC University Medical Centre, 3000 CB Rotterdam, The Netherlands.</aff><aff id="A179"><label>179</label>Department for Health Evidence, Radboud University Medical Centre, 6500 HB Nijmegen, The Netherlands.</aff><aff id="A180"><label>180</label>Department of Genetics, Radboud University Medical Centre, 6500 HB Nijmegen, The Netherlands.</aff><aff id="A181"><label>181</label>Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.</aff><aff id="A182"><label>182</label>Genetics, GlaxoSmithKline, King of Prussia, Pennsylvania 19406, USA.</aff><aff id="A183"><label>183</label>German Center for Cardiovascular Research, partner site Hamburg/Lubeck/Kiel, 23562 Lubeck, Germany.</aff><aff id="A184"><label>184</label>Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, D-23562 Lübeck, Germany.</aff><aff id="A185"><label>185</label>Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, 9037 Tromsø, Norway.</aff><aff id="A186"><label>186</label>MRC Unit for Lifelong Health and Ageing at University College London, London WC1B 5JU, UK.</aff><aff id="A187"><label>187</label>Diabetes Complications Research Centre, Conway Institute, School of Medicine and Medical Sciences, University College Dublin, Dublin 4, Ireland.</aff><aff id="A188"><label>188</label>Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea.</aff><aff id="A189"><label>189</label>Lady Davis Institute, Departments of Human Genetics, Epidemiology and Biostatistics, McGill University, Montréal, Québec H3T1E2, Canada.</aff><aff id="A190"><label>190</label>Cardiothoracic Surgery Unit, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm 17176, Sweden.</aff><aff id="A191"><label>191</label>Department of Medicine, Columbia University College of Physicians and Surgeons, New York 10032, USA.</aff><aff id="A192"><label>192</label>Biosciences Research Division, Department of Primary Industries, Victoria 3083, Australia.</aff><aff id="A193"><label>193</label>Department of Food and Agricultural Systems, University of Melbourne, Victoria 3010, Australia.</aff><aff id="A194"><label>194</label>Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA.</aff><aff id="A195"><label>195</label>State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Rui Jin Hospital Affiliated with Shanghai Jiao Tong University School of Medicine, Shanghai, China.</aff><aff id="A196"><label>196</label>NIHR Oxford Biomedical Research Centre, OUH Trust, Oxford OX3 7LE, UK.</aff><aff id="A197"><label>197</label>Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.</aff><aff id="A198"><label>198</label>Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Yokohama 230-0045, Japan.</aff><aff id="A199"><label>199</label>Center for Genome Science, National Institute of Health, Chungcheongbuk-do, Chungbuk 363–951, Republic of Korea.</aff><aff id="A200"><label>200</label>Harvard School of Public Health, Department of Biostatistics, Harvard University, Boston, Massachusetts 2115, USA.</aff><aff id="A201"><label>201</label>Department of Genetics, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, New Haven, Connecticut 06520, USA.</aff><aff id="A202"><label>202</label>College of Information Science and Technology, Dalian Maritime University, Dalian, Liaoning 116026, China.</aff><aff id="A203"><label>203</label>Nephrology Research, Centre for Public Health, Queen’s University of Belfast, Belfast, County Down BT9 7AB, UK.</aff><aff id="A204"><label>204</label>Section of General Internal Medicine, Boston University School of Medicine, Boston, Massachusetts 02118, USA.</aff><aff id="A205"><label>205</label>Department of Statistics, University of Oxford, 1 South Parks Road, Oxford OX1 3TG, UK.</aff><aff id="A206"><label>206</label>MRC Harwell, Harwell Science and Innovation Campus, Harwell OX11 0QG, UK.</aff><aff id="A207"><label>207</label>Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland 4059, Australia.</aff><aff id="A208"><label>208</label>Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama 230-0045, Japan.</aff><aff id="A209"><label>209</label>Department of Human Genetics and Disease Diversity, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 113-8510 Tokyo, Japan.</aff><aff id="A210"><label>210</label>Genome Institute of Singapore, Agency for Science, Technology and Research, 138672 Singapore.</aff><aff id="A211"><label>211</label>Department of Biomedical Engineering and Computational Science, Aalto University School of Science, Helsinki FI-00076, Finland.</aff><aff id="A212"><label>212</label>Department of Medicine, Division of Nephrology, Helsinki University Central Hospital, FI-00290 Helsinki, Finland.</aff><aff id="A213"><label>213</label>Folkhälsan Institute of Genetics, Folkhälsan Research Center, FI-00290 Helsinki, Finland.</aff><aff id="A214"><label>214</label>Laboratory for Cardiovascular Diseases, RIKEN Center for Integrative Medical Sciences, Yokohama 230-0045, Japan.</aff><aff id="A215"><label>215</label>Division of Disease Diversity, Bioresource Research Center, Tokyo Medical and Dental University, 113-8510 Tokyo, Japan.</aff><aff id="A216"><label>216</label>Division of Epidemiology, Department of Medicine; Vanderbilt Epidemiology Center; and Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee 37075, USA.</aff><aff id="A217"><label>217</label>Nuffield Department of Obstetrics & Gynaecology, University of Oxford, Oxford OX3 7BN, UK.</aff><aff id="A218"><label>218</label>Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA.</aff><aff id="A219"><label>219</label>Department of Epidemiology and Public Health, EA3430, University of Strasbourg, Faculty of Medicine, Strasbourg, France.</aff><aff id="A220"><label>220</label>Department of Internal Medicine, University Medical Center Groningen, University of Groningen, 9700RB Groningen, The Netherlands.</aff><aff id="A221"><label>221</label>Pathology and Laboratory Medicine, The University of Western Australia, Perth, Western Australia 6009, Australia.</aff><aff id="A222"><label>222</label>Cedars-Sinai Diabetes and Obesity Research Institute, Los Angeles, California 90048, USA.</aff><aff id="A223"><label>223</label>Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois and University of Lausanne, 1010 Lausanne, Switzerland.</aff><aff id="A224"><label>224</label>Ministry of Health, Victoria, Republic of Seychelles.</aff><aff id="A225"><label>225</label>University of Milano, Bicocca, 20126, Italy.</aff><aff id="A226"><label>226</label>Harvard Medical School, Boston, Massachusetts 02115, USA.</aff><aff id="A227"><label>227</label>Center for Human Genetics Research, Vanderbilt University Medical Center, Nashville, Tennessee 37203, USA.</aff><aff id="A228"><label>228</label>Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee 37232, USA.</aff><aff id="A229"><label>229</label>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA.</aff><aff id="A230"><label>230</label>Department of Health Sciences, University of Milano, I 20142, Italy.</aff><aff id="A231"><label>231</label>Fondazione Filarete, Milano I 20139, Italy.</aff><aff id="A232"><label>232</label>Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK.</aff><aff id="A233"><label>233</label>Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.</aff><aff id="A234"><label>234</label>Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK.</aff><aff id="A235"><label>235</label>Clinic of Cardiology, West-German Heart Centre, University Hospital Essen, 45147 Essen, Germany.</aff><aff id="A236"><label>236</label>Department of General Practice and Primary Health Care, University of Helsinki, FI-00290 Helsinki, Finland.</aff><aff id="A237"><label>237</label>Unit of General Practice, Helsinki University Central Hospital, Helsinki 00290, Finland.</aff><aff id="A238"><label>238</label>Department of Internal Medicine B, University Medicine Greifswald, D-17475 Greifswald, Germany.</aff><aff id="A239"><label>239</label>DZHK (Deutsches Zentrum für Herz-Kreislaufforschung – German Centre for Cardiovascular Research), partner site Greifswald, D-17475 Greifswald, Germany.</aff><aff id="A240"><label>240</label>Department of Internal Medicine, University of Pisa, 56100 Pisa, Italy.</aff><aff id="A241"><label>241</label>National Research Council Institute of Clinical Physiology, University of Pisa, 56124 Pisa, Italy.</aff><aff id="A242"><label>242</label>Department of Cardiology, Toulouse University School of Medicine, Rangueil Hospital, 31400 Toulouse, France.</aff><aff id="A243"><label>243</label>Robertson Center for Biostatistics, University of Glasgow, Glasgow G12 8QQ, UK.</aff><aff id="A244"><label>244</label>UWI Solutions for Developing Countries, The University of the West Indies, Mona, Kingston 7, Jamaica.</aff><aff id="A245"><label>245</label>NorthShore University HealthSystem, Evanston, IL 60201, University of Chicago, Chicago, Illinois, USA.</aff><aff id="A246"><label>246</label>Leeds MRC Medical Bioinformatics Centre, University of Leeds, Leeds LS2 9LU, UK.</aff><aff id="A247"><label>247</label>Institute of Biomedical & Clinical Science, University of Exeter, Barrack Road, Exeter EX2 5DW, UK.</aff><aff id="A248"><label>248</label>Center for Biomedicine, European Academy Bozen, Bolzano (EURAC), Bolzano 39100, Italy (affiliated institute of the University of Lübeck, D-23562 Lübeck, Germany).</aff><aff id="A249"><label>249</label>Division of Genomic Medicine, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.</aff><aff id="A250"><label>250</label>Institute of Cardiovascular Science, University College London, London WC1E 6BT, UK.</aff><aff id="A251"><label>251</label>Department of Vascular Medicine, Academic Medical Center, 1105 AZ Amsterdam, The Netherlands.</aff><aff id="A252"><label>252</label>Centre for Cardiovascular Genetics, Institute Cardiovascular Sciences, University College London, London WC1E 6JJ, UK.</aff><aff id="A253"><label>253</label>Cardiovascular Genetics Division, Department of Internal Medicine, University of Utah, Salt Lake City, Utah 84108, USA.</aff><aff id="A254"><label>254</label>Sansom Institute for Health Research, University of South Australia, Adelaide 5000, South Australia, Australia.</aff><aff id="A255"><label>255</label>School of Population Health, University of South Australia, Adelaide 5000, South Australia, Australia.</aff><aff id="A256"><label>256</label>South Australian Health and Medical Research Institute, Adelaide, South Australia 5000, Australia.</aff><aff id="A257"><label>257</label>Population, Policy, and Practice, University College London Institute of Child Health, London WC1N 1EH, UK.</aff><aff id="A258"><label>258</label>Hannover Unified Biobank, Hannover Medical School, Hannover, D-30625 Hannover, Germany.</aff><aff id="A259"><label>259</label>National Institute for Health and Welfare, FI-90101 Oulu, Finland.</aff><aff id="A260"><label>260</label>MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College London, London W2 1PG, UK.</aff><aff id="A261"><label>261</label>Unit of Primary Care, Oulu University Hospital, FI-90220 Oulu, Finland.</aff><aff id="A262"><label>262</label>Biocenter Oulu, University of Oulu, FI-90014 Oulu, Finland.</aff><aff id="A263"><label>263</label>Institute of Health Sciences, University of Oulu, FI-90014 Oulu, Finland.</aff><aff id="A264"><label>264</label>Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands (ICIN), 3501 DG Utrecht, The Netherlands.</aff><aff id="A265"><label>265</label>Interuniversity Cardiology Institute of the Netherlands (ICIN), 3501 DG Utrecht, The Netherlands.</aff><aff id="A266"><label>266</label>Unit of Primary Health Care/General Practice, Oulu University Hospital, FI-90220 Oulu, Finland.</aff><aff id="A267"><label>267</label>Department of Urology, Radboud University Medical Centre, 6500 HB Nijmegen, The Netherlands.</aff><aff id="A268"><label>268</label>Imperial College Healthcare NHS Trust, London W12 0HS, UK.</aff><aff id="A269"><label>269</label>Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK.</aff><aff id="A270"><label>270</label>Department of Biological and Social Epidemiology, University of Essex, Wivenhoe Park, Colchester, Essex CO4 3SQ, UK.</aff><aff id="A271"><label>271</label>Department of Medicine, Kuopio University Hospital and University of Eastern Finland, FI-70210 Kuopio, Finland.</aff><aff id="A272"><label>272</label>Department of Physiology, Institute of Biomedicine, University of Eastern Finland, Kuopio Campus, FI-70211 Kuopio, Finland.</aff><aff id="A273"><label>273</label>Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital and University of Eastern Finland, FI-70210 Kuopio, Finland.</aff><aff id="A274"><label>274</label>Department of Clinical Chemistry, Fimlab Laboratories and School of Medicine University of Tampere, FI-33520 Tampere, Finland.</aff><aff id="A275"><label>275</label>Steno Diabetes Center A/S, Gentofte DK-2820, Denmark.</aff><aff id="A276"><label>276</label>Lund University Diabetes Centre and Department of Clinical Science, Diabetes & Endocrinology Unit, Lund University, Malmö 221 00, Sweden.</aff><aff id="A277"><label>277</label>Institut Universitaire de Cardiologie et de Pneumologie de Québec, Faculty of Medicine, Laval University, Quebec, QC G1V 0A6, Canada.</aff><aff id="A278"><label>278</label>Institute of Nutrition and Functional Foods, Laval University, Quebec, QC G1V 0A6, Canada.</aff><aff id="A279"><label>279</label>Department of Biostatistics, University of Washington, Seattle, Washington 98195, USA.</aff><aff id="A280"><label>280</label>Department of Surgery, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.</aff><aff id="A281"><label>281</label>Department of Biostatistics, University of Liverpool, Liverpool L69 3GA, UK.</aff><aff id="A282"><label>282</label>Department of Pediatrics, University of Iowa, Iowa City, Iowa 52242, USA.</aff><aff id="A283"><label>283</label>Illumina, Inc, Little Chesterford, Cambridge CB10 1XL, UK.</aff><aff id="A284"><label>284</label>University of Groningen, University Medical Center Groningen, Department of Pulmonary Medicine and Tuberculosis, Groningen, The Netherlands.</aff><aff id="A285"><label>285</label>Department of Neurology, General Central Hospital, Bolzano 39100, Italy.</aff><aff id="A286"><label>286</label>Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, FI-20521 Turku, Finland.</aff><aff id="A287"><label>287</label>Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, FI-20521 Turku, Finland.</aff><aff id="A288"><label>288</label>Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808, USA.</aff><aff id="A289"><label>289</label>Université de Montréal, Montreal, Quebec H1T 1C8, Canada.</aff><aff id="A290"><label>290</label>Center for Systems Genomics, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.</aff><aff id="A291"><label>291</label>Croatian Centre for Global Health, Faculty of Medicine, University of Split, 21000 Split, Croatia.</aff><aff id="A292"><label>292</label>South Carelia Central Hospital, 53130 Lappeenranta, Finland.</aff><aff id="A293"><label>293</label>Paul Langerhans Institute Dresden, German Center for Diabetes Research (DZD), 01307 Dresden, Germany.</aff><aff id="A294"><label>294</label>International Centre for Circulatory Health, Imperial College London, London W2 1PG, UK.</aff><aff id="A295"><label>295</label>Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.</aff><aff id="A296"><label>296</label>Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.</aff><aff id="A297"><label>297</label>Geriatric Research and Education Clinical Center, Vetrans Administration Medical Center, Baltimore, Maryland 21201, USA.</aff><aff id="A298"><label>298</label>Helsinki University Central Hospital Heart and Lung Center, Department of Medicine, Helsinki University Central Hospital, FI-00290 Helsinki, Finland.</aff><aff id="A299"><label>299</label>Sorbonne Universités, UPMC Univ Paris 06, UMR S 1166, F-75013 Paris, France.</aff><aff id="A300"><label>300</label>INSERM, UMR S 1166, Team Genomics and Physiopathology of Cardiovascular Diseases, F-75013 Paris, France.</aff><aff id="A301"><label>301</label>Institute for Cardiometabolism And Nutrition (ICAN), F-75013 Paris, France.</aff><aff id="A302"><label>302</label>Department of Kinesiology, Laval University, Quebec QC G1V 0A6, Canada.</aff><aff id="A303"><label>303</label>Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano & Centro Cardiologico Monzino, Instituto di Ricovero e Cura a Carattere Scientifico, Milan 20133, Italy.</aff><aff id="A304"><label>304</label>Department of Food Science and Nutrition, Laval University, Quebec QC G1V 0A6, Canada.</aff><aff id="A305"><label>305</label>Department of Internal Medicine, University Hospital (CHUV) and University of Lausanne, Lausanne 1011, Switzerland.</aff><aff id="A306"><label>306</label>Department of Nutrition, University of North Carolina, Chapel Hill, North Carolina 27599, USA.</aff><aff id="A307"><label>307</label>Institut Pasteur de Lille; INSERM, U744; Université de Lille 2; F-59000 Lille, France.</aff><aff id="A308"><label>308</label>Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.</aff><aff id="A309"><label>309</label>Department of Medicine, Stanford University School of Medicine, Palo Alto, California 94304, USA.</aff><aff id="A310"><label>310</label>Lee Kong Chian School of Medicine, Imperial College London and Nanyang Technological University, Singapore, 637553 Singapore, Singapore.</aff><aff id="A311"><label>311</label>Department of Internal Medicine I, Ulm University Medical Centre, D-89081 Ulm, Germany.</aff><aff id="A312"><label>312</label>Health Science Center at Houston, University of Texas, Houston, Texas 77030, USA.</aff><aff id="A313"><label>313</label>Department of Medicine, Division of Genetics, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.</aff><aff id="A314"><label>314</label>Department of Epidemiology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.</aff><aff id="A315"><label>315</label>School of Population Health, The University of Western Australia, Nedlands, Western Australia 6009, Australia.</aff><aff id="A316"><label>316</label>Albert Einstein College of Medicine, Department of Epidemiology and Population Health, Belfer 1306, New York 10461, USA.</aff><aff id="A317"><label>317</label>Center for Human Genetics, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, USA.</aff><aff id="A318"><label>318</label>Synlab Academy, Synlab Services GmbH, 68163 Mannheim, Germany.</aff><aff id="A319"><label>319</label>Department of Clinical Medicine, Copenhagen University, 2200 Copenhagen, Denmark.</aff><aff id="A320"><label>320</label>Department of Clinical Genetics, Erasmus MC University Medical Center, 3000 CA Rotterdam, The Netherlands.</aff><aff id="A321"><label>321</label>Finnish Diabetes Association, Kirjoniementie 15, FI-33680 Tampere, Finland.</aff><aff id="A322"><label>322</label>Pirkanmaa Hospital District, FI-33521 Tampere, Finland.</aff><aff id="A323"><label>323</label>Center for Non-Communicable Diseases, Karatchi, Pakistan.</aff><aff id="A324"><label>324</label>Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.</aff><aff id="A325"><label>325</label>BHF Glasgow Cardiovascular Research Centre, Division of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G12 8TA, UK.</aff><aff id="A326"><label>326</label>Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10580, USA.</aff><aff id="A327"><label>327</label>Faculty of Medicine, University of Iceland, Reykjavik 101, Iceland.</aff><aff id="A328"><label>328</label>Institute for Health Research, University Hospital of La Paz (IdiPaz), 28046 Madrid, Spain.</aff><aff id="A329"><label>329</label>Diabetes Research Group, King Abdulaziz University, 21589 Jeddah, Saudi Arabia.</aff><aff id="A330"><label>330</label>Centre for Vascular Prevention, Danube-University Krems, 3500 Krems, Austria.</aff><aff id="A331"><label>331</label>Department of Public Health and Clinical Nutrition, University of Eastern Finland, Finland.</aff><aff id="A332"><label>332</label>Research Unit, Kuopio University Hospital, FI-70210 Kuopio, Finland.</aff><aff id="A333"><label>333</label>Institute of Cellular Medicine, Newcastle University, Newcastle NE1 7RU, UK.</aff><aff id="A334"><label>334</label>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, D-17475 Greifswald, Germany.</aff><aff id="A335"><label>335</label>Institute of Medical Informatics, Biometry and Epidemiology, Chair of Epidemiology, Ludwig-Maximilians-Universität, D-85764 Munich, Germany.</aff><aff id="A336"><label>336</label>Klinikum Grosshadern, D-81377 Munich, Germany.</aff><aff id="A337"><label>337</label>Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany, D-85764 Neuherberg, Germany.</aff><aff id="A338"><label>338</label>Department of Pulmonology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.</aff><aff id="A339"><label>339</label>Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, 21589 Jeddah, Saudi Arabia.</aff><aff id="A340"><label>340</label>Division of Population Health Sciences & Education, St George’s, University of London, London SW17 0RE, UK.</aff><aff id="A341"><label>341</label>Oxford NIHR Biomedical Research Centre, Oxford University Hospitals NHS Trust, Oxford OX3 7LJ, UK.</aff><aff id="A342"><label>342</label>Clinical Epidemiology, Integrated Research and Treatment Center, Center for Sepsis Control and Care (CSCC), Jena University Hospital, 07743 Jena, Germany.</aff><aff id="A343"><label>343</label>Department of Human Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA.</aff><aff id="A344"><label>344</label>Service of Medical Genetics, CHUV University Hospital, 1011 Lausanne, Switzerland.</aff><aff id="A345"><label>345</label>University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge CB2 OQQ, UK.</aff><aff id="A346"><label>346</label>NIHR Cambridge Biomedical Research Centre, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge CB2 OQQ, UK.</aff><aff id="A347"><label>347</label>Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.</aff><aff id="A348"><label>348</label>The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</aff><author-notes><corresp id="CR1">Correspondence and requests for materials should be addressed to E.K.S. (<email>espeliot@med.umich.edu</email>), R.J.F.L. (<email>ruth.loos@mssm.edu</email>), and J.N.H. (<email>joelh@broadinstitute.org</email>).</corresp><fn fn-type="present-address" id="FN1"><label>†</label><p id="P1">Present address: Second Floor, B-dong, AICT Building, 145 Gwanggyo-ro, Yeongyong-gu, Suwon-si, Gyeonggi-do,443-270, South Korea.</p></fn><fn id="FN2"><label>‡</label><p id="P2">A list of authors and affiliations appears in the <xref ref-type="supplementary-material" rid="SD1">Supplementary Information</xref>.</p></fn><fn id="FN3"><label>§</label><p id="P3">These authors jointly supervised this work.</p></fn></author-notes><pub-date pub-type="nihms-submitted"><day>3</day><month>3</month><year>2015</year></pub-date><pub-date pub-type="ppub"><day>12</day><month>2</month><year>2015</year></pub-date><pub-date pub-type="pmc-release"><day>01</day><month>4</month><year>2015</year></pub-date><volume>518</volume><issue>7538</issue><fpage>197</fpage><lpage>206</lpage><pmc-comment>elocation-id from pubmed: 10.1038/nature14177</pmc-comment>
<abstract><p id="P4">Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity better, here we conduct a genome-wide association study and Metabochip meta-analysis of body mass index (BMI), a measure commonly used to define obesity and assess adiposity, in up to 339,224 individuals. This analysis identifies 97 BMI-associated loci (<italic>P</italic> < 5 × 10<sup>−8</sup>), 56 of which are novel. Five loci demonstrate clear evidence of several independent association signals, and many loci have significant effects on other metabolic phenotypes. The 97 loci account for ~2.7% of BMI variation, and genome-wide estimates suggest that common variation accounts for >20% of BMI variation. Pathway analyses provide strong support for a role of the central nervous system in obesity susceptibility and implicate new genes and pathways, including those related to synaptic function, glutamate signalling, insulin secretion/action, energy metabolism, lipid biology and adipogenesis.</p></abstract></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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