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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Sexual Health in Hematopoietic Stem Cell Transplant Recipients</title>
<author><name sortKey="Li, Zhuoyan" sort="Li, Zhuoyan" uniqKey="Li Z" first="Zhuoyan" last="Li">Zhuoyan Li</name>
<affiliation><nlm:aff id="A1">Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Mewawalla, Prerna" sort="Mewawalla, Prerna" uniqKey="Mewawalla P" first="Prerna" last="Mewawalla">Prerna Mewawalla</name>
<affiliation><nlm:aff id="A2">Department of Hematology, Western Pennsylvania Cancer Institute, Pittsburgh, Pennsylvania</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Stratton, Pamela" sort="Stratton, Pamela" uniqKey="Stratton P" first="Pamela" last="Stratton">Pamela Stratton</name>
<affiliation><nlm:aff id="A3">Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Yong, Agnes S M" sort="Yong, Agnes S M" uniqKey="Yong A" first="Agnes S. M." last="Yong">Agnes S. M. Yong</name>
<affiliation><nlm:aff id="A4">Department of Haematology, SA Pathology, and School of Medicine, University of Adelaide, Adelaide, South Australia, Australia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Shaw, Bronwen E" sort="Shaw, Bronwen E" uniqKey="Shaw B" first="Bronwen E." last="Shaw">Bronwen E. Shaw</name>
<affiliation><nlm:aff id="A5">Center for International Blood and Marrow Transplant Research, Froedtert and the Medical College of Wisconsin, Milwaukee, Wisconsin</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hashmi, Shahrukh" sort="Hashmi, Shahrukh" uniqKey="Hashmi S" first="Shahrukh" last="Hashmi">Shahrukh Hashmi</name>
<affiliation><nlm:aff id="A6">Division of Hematology, Mayo Clinic, Rochester, Minnesota</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Jagasia, Madan" sort="Jagasia, Madan" uniqKey="Jagasia M" first="Madan" last="Jagasia">Madan Jagasia</name>
<affiliation><nlm:aff id="A7">Hematology and Stem Cell Transplantation Section, Division of Hematology/Oncology, Department of Medicine, Vanderbilt University Medical Center and Veterans Affairs Medical Center, Nashville, Tennessee</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Mohty, Mohamad" sort="Mohty, Mohamad" uniqKey="Mohty M" first="Mohamad" last="Mohty">Mohamad Mohty</name>
<affiliation><nlm:aff id="A8">INSERM (National Institute of Health and Medical Research) 938, Paris, France</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Majhail, Navneet S" sort="Majhail, Navneet S" uniqKey="Majhail N" first="Navneet S." last="Majhail">Navneet S. Majhail</name>
<affiliation><nlm:aff id="A9">Blood and Marrow Transplant Program, Cleveland Clinic, Cleveland, Ohio</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Savani, Bipin N" sort="Savani, Bipin N" uniqKey="Savani B" first="Bipin N." last="Savani">Bipin N. Savani</name>
<affiliation><nlm:aff id="A7">Hematology and Stem Cell Transplantation Section, Division of Hematology/Oncology, Department of Medicine, Vanderbilt University Medical Center and Veterans Affairs Medical Center, Nashville, Tennessee</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rov, Alicia" sort="Rov, Alicia" uniqKey="Rov A" first="Alicia" last="Rov">Alicia Rov</name>
<affiliation><nlm:aff id="A10">Department of Hematology, University Hospital of Bern, Bern, Switzerland</nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">26372459</idno>
<idno type="pmc">5014908</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014908</idno>
<idno type="RBID">PMC:5014908</idno>
<idno type="doi">10.1002/cncr.29675</idno>
<date when="2015">2015</date>
<idno type="wicri:Area/Pmc/Corpus">001D06</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001D06</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Sexual Health in Hematopoietic Stem Cell Transplant Recipients</title>
<author><name sortKey="Li, Zhuoyan" sort="Li, Zhuoyan" uniqKey="Li Z" first="Zhuoyan" last="Li">Zhuoyan Li</name>
<affiliation><nlm:aff id="A1">Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Mewawalla, Prerna" sort="Mewawalla, Prerna" uniqKey="Mewawalla P" first="Prerna" last="Mewawalla">Prerna Mewawalla</name>
<affiliation><nlm:aff id="A2">Department of Hematology, Western Pennsylvania Cancer Institute, Pittsburgh, Pennsylvania</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Stratton, Pamela" sort="Stratton, Pamela" uniqKey="Stratton P" first="Pamela" last="Stratton">Pamela Stratton</name>
<affiliation><nlm:aff id="A3">Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Yong, Agnes S M" sort="Yong, Agnes S M" uniqKey="Yong A" first="Agnes S. M." last="Yong">Agnes S. M. Yong</name>
<affiliation><nlm:aff id="A4">Department of Haematology, SA Pathology, and School of Medicine, University of Adelaide, Adelaide, South Australia, Australia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Shaw, Bronwen E" sort="Shaw, Bronwen E" uniqKey="Shaw B" first="Bronwen E." last="Shaw">Bronwen E. Shaw</name>
<affiliation><nlm:aff id="A5">Center for International Blood and Marrow Transplant Research, Froedtert and the Medical College of Wisconsin, Milwaukee, Wisconsin</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hashmi, Shahrukh" sort="Hashmi, Shahrukh" uniqKey="Hashmi S" first="Shahrukh" last="Hashmi">Shahrukh Hashmi</name>
<affiliation><nlm:aff id="A6">Division of Hematology, Mayo Clinic, Rochester, Minnesota</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Jagasia, Madan" sort="Jagasia, Madan" uniqKey="Jagasia M" first="Madan" last="Jagasia">Madan Jagasia</name>
<affiliation><nlm:aff id="A7">Hematology and Stem Cell Transplantation Section, Division of Hematology/Oncology, Department of Medicine, Vanderbilt University Medical Center and Veterans Affairs Medical Center, Nashville, Tennessee</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Mohty, Mohamad" sort="Mohty, Mohamad" uniqKey="Mohty M" first="Mohamad" last="Mohty">Mohamad Mohty</name>
<affiliation><nlm:aff id="A8">INSERM (National Institute of Health and Medical Research) 938, Paris, France</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Majhail, Navneet S" sort="Majhail, Navneet S" uniqKey="Majhail N" first="Navneet S." last="Majhail">Navneet S. Majhail</name>
<affiliation><nlm:aff id="A9">Blood and Marrow Transplant Program, Cleveland Clinic, Cleveland, Ohio</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Savani, Bipin N" sort="Savani, Bipin N" uniqKey="Savani B" first="Bipin N." last="Savani">Bipin N. Savani</name>
<affiliation><nlm:aff id="A7">Hematology and Stem Cell Transplantation Section, Division of Hematology/Oncology, Department of Medicine, Vanderbilt University Medical Center and Veterans Affairs Medical Center, Nashville, Tennessee</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rov, Alicia" sort="Rov, Alicia" uniqKey="Rov A" first="Alicia" last="Rov">Alicia Rov</name>
<affiliation><nlm:aff id="A10">Department of Hematology, University Hospital of Bern, Bern, Switzerland</nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Cancer</title>
<idno type="ISSN">0008-543X</idno>
<idno type="eISSN">1097-0142</idno>
<imprint><date when="2015">2015</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p id="P1">Hematopoietic stem cell transplantation (HSCT) plays a central role in patients with malignant and, increasingly, nonmalignant conditions. As the number of transplants increases and the survival rate improves, long-term complications are important to recognize and treat to maintain quality of life. Sexual dysfunction is a commonly described but relatively often underestimated complication after HSCT. Conditioning regimens, generalized or genital graft-versus-host disease, medications, and cardiovascular complications as well as psychosocial problems are known to contribute significantly to physical and psychological sexual dysfunction. Moreover, it is often a difficult topic for patients, their significant others, and health care providers to discuss. Early recognition and management of sexual dysfunction after HSCT can lead to improved quality of life and outcomes for patients and their partners. This review focuses on the risk factors for and treatment of sexual dysfunction after transplantation and provides guidance concerning how to approach and manage a patient with sexual dysfunction after HSCT.</p>
</div>
</front>
</TEI>
<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">0374236</journal-id>
<journal-id journal-id-type="pubmed-jr-id">2771</journal-id>
<journal-id journal-id-type="nlm-ta">Cancer</journal-id>
<journal-id journal-id-type="iso-abbrev">Cancer</journal-id>
<journal-title-group><journal-title>Cancer</journal-title>
</journal-title-group>
<issn pub-type="ppub">0008-543X</issn>
<issn pub-type="epub">1097-0142</issn>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">26372459</article-id>
<article-id pub-id-type="pmc">5014908</article-id>
<article-id pub-id-type="doi">10.1002/cncr.29675</article-id>
<article-id pub-id-type="manuscript">NIHMS812517</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>Sexual Health in Hematopoietic Stem Cell Transplant Recipients</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Li</surname>
<given-names>Zhuoyan</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Mewawalla</surname>
<given-names>Prerna</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="A2">2</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Stratton</surname>
<given-names>Pamela</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="A3">3</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Yong</surname>
<given-names>Agnes S.M.</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="A4">4</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Shaw</surname>
<given-names>Bronwen E.</given-names>
</name>
<degrees>MD, PhD</degrees>
<xref ref-type="aff" rid="A5">5</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Hashmi</surname>
<given-names>Shahrukh</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="A6">6</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Jagasia</surname>
<given-names>Madan</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="A7">7</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Mohty</surname>
<given-names>Mohamad</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="A8">8</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Majhail</surname>
<given-names>Navneet S.</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="A9">9</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Savani</surname>
<given-names>Bipin N.</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="A7">7</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Rovó</surname>
<given-names>Alicia</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="A10">10</xref>
</contrib>
</contrib-group>
<aff id="A1"><label>1</label>
Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee</aff>
<aff id="A2"><label>2</label>
Department of Hematology, Western Pennsylvania Cancer Institute, Pittsburgh, Pennsylvania</aff>
<aff id="A3"><label>3</label>
Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland</aff>
<aff id="A4"><label>4</label>
Department of Haematology, SA Pathology, and School of Medicine, University of Adelaide, Adelaide, South Australia, Australia</aff>
<aff id="A5"><label>5</label>
Center for International Blood and Marrow Transplant Research, Froedtert and the Medical College of Wisconsin, Milwaukee, Wisconsin</aff>
<aff id="A6"><label>6</label>
Division of Hematology, Mayo Clinic, Rochester, Minnesota</aff>
<aff id="A7"><label>7</label>
Hematology and Stem Cell Transplantation Section, Division of Hematology/Oncology, Department of Medicine, Vanderbilt University Medical Center and Veterans Affairs Medical Center, Nashville, Tennessee</aff>
<aff id="A8"><label>8</label>
INSERM (National Institute of Health and Medical Research) 938, Paris, France</aff>
<aff id="A9"><label>9</label>
Blood and Marrow Transplant Program, Cleveland Clinic, Cleveland, Ohio</aff>
<aff id="A10"><label>10</label>
Department of Hematology, University Hospital of Bern, Bern, Switzerland</aff>
<author-notes><corresp id="FN1">Corresponding author: Bipin N. Savani, MD, Hematology and Stem Cell Transplantation Section, Division of Hematology/Oncology, Department of Medicine, Vanderbilt University Medical Center, 1301 Medical Center Dr, 3927 TVC, Nashville, TN; (615) 343-7602; <email>Bipin.Savani@Vanderbilt.Edu</email>
</corresp>
<fn id="FN2" fn-type="equal"><p>The first 2 authors contributed equally to this work.</p>
</fn>
<fn id="FN3"><p>The last 2 authors share senior authorship.</p>
</fn>
</author-notes>
<pub-date pub-type="nihms-submitted"><day>25</day>
<month>8</month>
<year>2016</year>
</pub-date>
<pub-date pub-type="epub"><day>15</day>
<month>9</month>
<year>2015</year>
</pub-date>
<pub-date pub-type="ppub"><day>1</day>
<month>12</month>
<year>2015</year>
</pub-date>
<pub-date pub-type="pmc-release"><day>08</day>
<month>9</month>
<year>2016</year>
</pub-date>
<volume>121</volume>
<issue>23</issue>
<fpage>4124</fpage>
<lpage>4131</lpage>
<pmc-comment>elocation-id from pubmed: 10.1002/cncr.29675</pmc-comment>
<abstract><p id="P1">Hematopoietic stem cell transplantation (HSCT) plays a central role in patients with malignant and, increasingly, nonmalignant conditions. As the number of transplants increases and the survival rate improves, long-term complications are important to recognize and treat to maintain quality of life. Sexual dysfunction is a commonly described but relatively often underestimated complication after HSCT. Conditioning regimens, generalized or genital graft-versus-host disease, medications, and cardiovascular complications as well as psychosocial problems are known to contribute significantly to physical and psychological sexual dysfunction. Moreover, it is often a difficult topic for patients, their significant others, and health care providers to discuss. Early recognition and management of sexual dysfunction after HSCT can lead to improved quality of life and outcomes for patients and their partners. This review focuses on the risk factors for and treatment of sexual dysfunction after transplantation and provides guidance concerning how to approach and manage a patient with sexual dysfunction after HSCT.</p>
</abstract>
<kwd-group><kwd>late effects</kwd>
<kwd>sexual health</kwd>
<kwd>survivorship</kwd>
<kwd>toxicity</kwd>
<kwd>transplantation</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>
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