Links to Exploration step
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium</title><author><name sortKey="Broeks, Annegien" sort="Broeks, Annegien" uniqKey="Broeks A" first="Annegien" last="Broeks">Annegien Broeks</name><affiliation><nlm:aff id="af1"><addr-line>Department of Experimental Therapy</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Schmidt, Marjanka K" sort="Schmidt, Marjanka K" uniqKey="Schmidt M" first="Marjanka K." last="Schmidt">Marjanka K. Schmidt</name><affiliation><nlm:aff id="af1"><addr-line>Department of Experimental Therapy</addr-line>,</nlm:aff></affiliation><affiliation><nlm:aff wicri:cut=" and" id="af2"><addr-line>Department of Epidemiology</addr-line></nlm:aff></affiliation></author><author><name sortKey="Sherman, Mark E" sort="Sherman, Mark E" uniqKey="Sherman M" first="Mark E." last="Sherman">Mark E. Sherman</name><affiliation><nlm:aff id="af4"><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Rockville, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Couch, Fergus J" sort="Couch, Fergus J" uniqKey="Couch F" first="Fergus J." last="Couch">Fergus J. Couch</name><affiliation><nlm:aff wicri:cut=" and" id="af5"><addr-line>Department of Laboratory Medicine and Pathology</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af6"><addr-line>Department of Health Sciences Research</addr-line>,<institution>Mayo Clinic</institution>,<addr-line>Rochester, MN</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Hopper, John L" sort="Hopper, John L" uniqKey="Hopper J" first="John L." last="Hopper">John L. Hopper</name><affiliation><nlm:aff wicri:cut=" and" id="af7"><institution>Centre for Molecular, Environmental, Genetic and Analytic Epidemiology</institution></nlm:aff></affiliation></author><author><name sortKey="Dite, Gillian S" sort="Dite, Gillian S" uniqKey="Dite G" first="Gillian S." last="Dite">Gillian S. Dite</name><affiliation><nlm:aff wicri:cut=" and" id="af7"><institution>Centre for Molecular, Environmental, Genetic and Analytic Epidemiology</institution></nlm:aff></affiliation></author><author><name sortKey="Apicella, Carmel" sort="Apicella, Carmel" uniqKey="Apicella C" first="Carmel" last="Apicella">Carmel Apicella</name><affiliation><nlm:aff wicri:cut=" and" id="af7"><institution>Centre for Molecular, Environmental, Genetic and Analytic Epidemiology</institution></nlm:aff></affiliation></author><author><name sortKey="Smith, Letitia D" sort="Smith, Letitia D" uniqKey="Smith L" first="Letitia D." last="Smith">Letitia D. Smith</name><affiliation><nlm:aff id="af8"><addr-line>Genetic Epidemiology Laboratory, Department of Pathology</addr-line>,<institution>The University of Melbourne</institution>,<country>Australia</country>,</nlm:aff></affiliation></author><author><name sortKey="Hammet, Fleur" sort="Hammet, Fleur" uniqKey="Hammet F" first="Fleur" last="Hammet">Fleur Hammet</name><affiliation><nlm:aff id="af8"><addr-line>Genetic Epidemiology Laboratory, Department of Pathology</addr-line>,<institution>The University of Melbourne</institution>,<country>Australia</country>,</nlm:aff></affiliation></author><author><name sortKey="Southey, Melissa C" sort="Southey, Melissa C" uniqKey="Southey M" first="Melissa C." last="Southey">Melissa C. Southey</name><affiliation><nlm:aff id="af8"><addr-line>Genetic Epidemiology Laboratory, Department of Pathology</addr-line>,<institution>The University of Melbourne</institution>,<country>Australia</country>,</nlm:aff></affiliation></author><author><name sortKey="Van Veer, Laura J" sort="Van Veer, Laura J" uniqKey="Van Veer L" first="Laura J." last="Van Veer">Laura J. Van Veer</name><affiliation><nlm:aff id="af1"><addr-line>Department of Experimental Therapy</addr-line>,</nlm:aff></affiliation><affiliation><nlm:aff id="af3"><addr-line>Department of Molecular Pathology</addr-line>,<institution>The Netherlands Cancer Institute</institution>,<addr-line>Amsterdam</addr-line>,<country>the Netherlands</country>,</nlm:aff></affiliation></author><author><name sortKey="De Groot, Renate" sort="De Groot, Renate" uniqKey="De Groot R" first="Renate" last="De Groot">Renate De Groot</name><affiliation><nlm:aff id="af3"><addr-line>Department of Molecular Pathology</addr-line>,<institution>The Netherlands Cancer Institute</institution>,<addr-line>Amsterdam</addr-line>,<country>the Netherlands</country>,</nlm:aff></affiliation></author><author><name sortKey="Smit, Vincent T H B M" sort="Smit, Vincent T H B M" uniqKey="Smit V" first="Vincent T. H. B. M." last="Smit">Vincent T. H. B. M. Smit</name><affiliation><nlm:aff id="af9"><addr-line>Department of Pathology</addr-line>,<institution>Leiden University Medical Centre</institution>,<addr-line>Leiden</addr-line>,<country>the Netherlands</country>,</nlm:aff></affiliation></author><author><name sortKey="Fasching, Peter A" sort="Fasching, Peter A" uniqKey="Fasching P" first="Peter A." last="Fasching">Peter A. Fasching</name><affiliation><nlm:aff id="af10"><addr-line>Division of Hematology and Oncology, David Geffen School of Medicine</addr-line>,<institution>University of California at Los Angeles</institution>,<addr-line>Los Angeles, CA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Beckmann, Matthias W" sort="Beckmann, Matthias W" uniqKey="Beckmann M" first="Matthias W." last="Beckmann">Matthias W. Beckmann</name><affiliation><nlm:aff id="af11"><addr-line>Department of Gynecology and Obstetrics</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Jud, Sebastian" sort="Jud, Sebastian" uniqKey="Jud S" first="Sebastian" last="Jud">Sebastian Jud</name><affiliation><nlm:aff id="af11"><addr-line>Department of Gynecology and Obstetrics</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Ekici, Arif B" sort="Ekici, Arif B" uniqKey="Ekici A" first="Arif B." last="Ekici">Arif B. Ekici</name><affiliation><nlm:aff id="af14"><addr-line>Institute of Human Genetics</addr-line>,<institution>Friedrich Alexander University Erlangen</institution>,<addr-line>Nürnberg</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Hartmann, Arndt" sort="Hartmann, Arndt" uniqKey="Hartmann A" first="Arndt" last="Hartmann">Arndt Hartmann</name><affiliation><nlm:aff id="af12"><addr-line>Institute of Pathology</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Hein, Alexander" sort="Hein, Alexander" uniqKey="Hein A" first="Alexander" last="Hein">Alexander Hein</name><affiliation><nlm:aff id="af11"><addr-line>Department of Gynecology and Obstetrics</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Schulz Wendtland, Ruediger" sort="Schulz Wendtland, Ruediger" uniqKey="Schulz Wendtland R" first="Ruediger" last="Schulz-Wendtland">Ruediger Schulz-Wendtland</name><affiliation><nlm:aff id="af13"><addr-line>Institute of Radiology</addr-line>,<institution>University Breast Center</institution>,<institution>University Hospital Erlangen</institution>,<addr-line>Erlangen</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Burwinkel, Barbara" sort="Burwinkel, Barbara" uniqKey="Burwinkel B" first="Barbara" last="Burwinkel">Barbara Burwinkel</name><affiliation><nlm:aff wicri:cut=" and" id="af15"><addr-line>Department of Gynecology and Obstetrics</addr-line></nlm:aff></affiliation><affiliation><nlm:aff wicri:cut=" and" id="af17"><addr-line>Molecular Epidemiology</addr-line></nlm:aff></affiliation></author><author><name sortKey="Marme, Frederik" sort="Marme, Frederik" uniqKey="Marme F" first="Frederik" last="Marme">Frederik Marme</name><affiliation><nlm:aff wicri:cut=" and" id="af15"><addr-line>Department of Gynecology and Obstetrics</addr-line></nlm:aff></affiliation></author><author><name sortKey="Schneeweiss, Andreas" sort="Schneeweiss, Andreas" uniqKey="Schneeweiss A" first="Andreas" last="Schneeweiss">Andreas Schneeweiss</name><affiliation><nlm:aff wicri:cut=" and" id="af15"><addr-line>Department of Gynecology and Obstetrics</addr-line></nlm:aff></affiliation></author><author><name sortKey="Sinn, Hans Peter" sort="Sinn, Hans Peter" uniqKey="Sinn H" first="Hans-Peter" last="Sinn">Hans-Peter Sinn</name><affiliation><nlm:aff id="af16"><addr-line>Department of Pathology</addr-line>,<institution>University Hospital Heidelberg</institution>,<addr-line>Heidelberg</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Sohn, Christof" sort="Sohn, Christof" uniqKey="Sohn C" first="Christof" last="Sohn">Christof Sohn</name><affiliation><nlm:aff wicri:cut=" and" id="af15"><addr-line>Department of Gynecology and Obstetrics</addr-line></nlm:aff></affiliation></author><author><name sortKey="Tchatchou, Sandrine" sort="Tchatchou, Sandrine" uniqKey="Tchatchou S" first="Sandrine" last="Tchatchou">Sandrine Tchatchou</name><affiliation><nlm:aff wicri:cut=" and" id="af15"><addr-line>Department of Gynecology and Obstetrics</addr-line></nlm:aff></affiliation><affiliation><nlm:aff wicri:cut=" and" id="af17"><addr-line>Molecular Epidemiology</addr-line></nlm:aff></affiliation></author><author><name sortKey="Bojesen, Stig E" sort="Bojesen, Stig E" uniqKey="Bojesen S" first="Stig E." last="Bojesen">Stig E. Bojesen</name><affiliation><nlm:aff wicri:cut=" and" id="af19"><addr-line>Department of Clinical Biochemistry</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af20"><addr-line>Department of Breast Surgery</addr-line>,<institution>Herlev University Hospital</institution>,<institution>University of Copenhagen</institution>, Copenhagen,<country>Denmark</country>,</nlm:aff></affiliation></author><author><name sortKey="Nordestgaard, B Rge G" sort="Nordestgaard, B Rge G" uniqKey="Nordestgaard B" first="B Rge G." last="Nordestgaard">B Rge G. Nordestgaard</name><affiliation><nlm:aff wicri:cut=" and" id="af19"><addr-line>Department of Clinical Biochemistry</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af20"><addr-line>Department of Breast Surgery</addr-line>,<institution>Herlev University Hospital</institution>,<institution>University of Copenhagen</institution>, Copenhagen,<country>Denmark</country>,</nlm:aff></affiliation></author><author><name sortKey="Flyger, Henrik" sort="Flyger, Henrik" uniqKey="Flyger H" first="Henrik" last="Flyger">Henrik Flyger</name><affiliation><nlm:aff wicri:cut=" and" id="af19"><addr-line>Department of Clinical Biochemistry</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af20"><addr-line>Department of Breast Surgery</addr-line>,<institution>Herlev University Hospital</institution>,<institution>University of Copenhagen</institution>, Copenhagen,<country>Denmark</country>,</nlm:aff></affiliation></author><author><name sortKey=" Rsted, David D" sort=" Rsted, David D" uniqKey=" Rsted D" first="David D." last=" Rsted">David D. Rsted</name><affiliation><nlm:aff wicri:cut=" and" id="af19"><addr-line>Department of Clinical Biochemistry</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af20"><addr-line>Department of Breast Surgery</addr-line>,<institution>Herlev University Hospital</institution>,<institution>University of Copenhagen</institution>, Copenhagen,<country>Denmark</country>,</nlm:aff></affiliation></author><author><name sortKey="Kaur Knudsen, Diljit" sort="Kaur Knudsen, Diljit" uniqKey="Kaur Knudsen D" first="Diljit" last="Kaur-Knudsen">Diljit Kaur-Knudsen</name><affiliation><nlm:aff wicri:cut=" and" id="af19"><addr-line>Department of Clinical Biochemistry</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af20"><addr-line>Department of Breast Surgery</addr-line>,<institution>Herlev University Hospital</institution>,<institution>University of Copenhagen</institution>, Copenhagen,<country>Denmark</country>,</nlm:aff></affiliation></author><author><name sortKey="Milne, Roger L" sort="Milne, Roger L" uniqKey="Milne R" first="Roger L." last="Milne">Roger L. Milne</name><affiliation><nlm:aff wicri:cut=" and" id="af21"><addr-line>Genetic & Molecular Epidemiology Group</addr-line></nlm:aff></affiliation></author><author><name sortKey="Perez, Jose I Arias" sort="Perez, Jose I Arias" uniqKey="Perez J" first="Jose I. Arias" last="Pérez">Jose I. Arias Pérez</name><affiliation><nlm:aff wicri:cut=" and" id="af23"><addr-line>Servicio Cirugía General</addr-line></nlm:aff></affiliation></author><author><name sortKey="Zamora, Pilar" sort="Zamora, Pilar" uniqKey="Zamora P" first="Pilar" last="Zamora">Pilar Zamora</name><affiliation><nlm:aff id="af25"><addr-line>Servicio de Oncología Médica</addr-line>,<institution>Hospital La Paz</institution>,<addr-line>Madrid</addr-line>,<country>Spain</country>,</nlm:aff></affiliation></author><author><name sortKey="Rodriguez, Primitiva Menendez" sort="Rodriguez, Primitiva Menendez" uniqKey="Rodriguez P" first="Primitiva Menéndez" last="Rodríguez">Primitiva Menéndez Rodríguez</name><affiliation><nlm:aff id="af24"><addr-line>Servicio de Anatomía Patológica</addr-line>,<institution>Hospital Monte Naranco</institution>,<addr-line>Oviedo</addr-line>,<country>Spain</country>,</nlm:aff></affiliation></author><author><name sortKey="Benitez, Javier" sort="Benitez, Javier" uniqKey="Benitez J" first="Javier" last="Benítez">Javier Benítez</name><affiliation><nlm:aff id="af22"><addr-line>Human Cancer Genetic Group</addr-line>,<institution>Spanish National Cancer Research Centre (CNIO)</institution>,<addr-line>Madrid</addr-line>,<country>Spain</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af26"><institution>CIBERER</institution>,<addr-line>Madrid</addr-line>,<country>Spain</country>,</nlm:aff></affiliation></author><author><name sortKey="Brauch, Hiltrud" sort="Brauch, Hiltrud" uniqKey="Brauch H" first="Hiltrud" last="Brauch">Hiltrud Brauch</name><affiliation><nlm:aff id="af27"><institution>Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology</institution>,<addr-line>Stuttgart</addr-line>,<country>Germany</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af28"><institution>University Tübingen</institution>,<addr-line>Tübingen</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Justenhoven, Christina" sort="Justenhoven, Christina" uniqKey="Justenhoven C" first="Christina" last="Justenhoven">Christina Justenhoven</name><affiliation><nlm:aff id="af27"><institution>Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology</institution>,<addr-line>Stuttgart</addr-line>,<country>Germany</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af28"><institution>University Tübingen</institution>,<addr-line>Tübingen</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Ko, Yon Dschun" sort="Ko, Yon Dschun" uniqKey="Ko Y" first="Yon-Dschun" last="Ko">Yon-Dschun Ko</name><affiliation><nlm:aff id="af29"><addr-line>Department of Internal Medicine</addr-line>,<institution>Evangelische Kliniken Bonn gGmbH</institution>,<addr-line>Johanniter Krankenhaus, Bonn</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Hamann, Ute" sort="Hamann, Ute" uniqKey="Hamann U" first="Ute" last="Hamann">Ute Hamann</name><affiliation><nlm:aff id="af32"><addr-line>Molecular Genetics of Breast Cancer</addr-line>,<institution>Deutsches Krebsforschungszentrum (DKFZ)</institution>,<addr-line>Heidelberg</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Fischer, Hans Peter" sort="Fischer, Hans Peter" uniqKey="Fischer H" first="Hans-Peter" last="Fischer">Hans-Peter Fischer</name><affiliation><nlm:aff id="af33"><institution>Institute of Pathology, Medical Faculty of the University of Bonn</institution>,<addr-line>Bonn</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Bruning, Thomas" sort="Bruning, Thomas" uniqKey="Bruning T" first="Thomas" last="Brüning">Thomas Brüning</name><affiliation><nlm:aff id="af34"><institution>Institute of Prevention and Occupational Medicine of the German Social Accident Insurance (IPA)</institution>,<addr-line>Bochum</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Pesch, Beate" sort="Pesch, Beate" uniqKey="Pesch B" first="Beate" last="Pesch">Beate Pesch</name><affiliation><nlm:aff id="af34"><institution>Institute of Prevention and Occupational Medicine of the German Social Accident Insurance (IPA)</institution>,<addr-line>Bochum</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Chang Claude, Jenny" sort="Chang Claude, Jenny" uniqKey="Chang Claude J" first="Jenny" last="Chang-Claude">Jenny Chang-Claude</name><affiliation><nlm:aff id="af18"><addr-line>Division of Cancer Epidemiology</addr-line>,<institution>German Cancer Research Center</institution>,<addr-line>Heidelberg</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Wang Gohrke, Shan" sort="Wang Gohrke, Shan" uniqKey="Wang Gohrke S" first="Shan" last="Wang-Gohrke">Shan Wang-Gohrke</name><affiliation><nlm:aff id="af35"><addr-line>Department of Obstetrics and Gynecology</addr-line>,<institution>University of Ulm</institution>,<addr-line>Ulm</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Bremer, Michael" sort="Bremer, Michael" uniqKey="Bremer M" first="Michael" last="Bremer">Michael Bremer</name><affiliation><nlm:aff id="af36"><addr-line>Hannover Medical School</addr-line>,<institution>Clinics of Radiation Oncology</institution>,<addr-line>Hannover</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Karstens, Johann H" sort="Karstens, Johann H" uniqKey="Karstens J" first="Johann H." last="Karstens">Johann H. Karstens</name><affiliation><nlm:aff id="af36"><addr-line>Hannover Medical School</addr-line>,<institution>Clinics of Radiation Oncology</institution>,<addr-line>Hannover</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Hillemanns, Peter" sort="Hillemanns, Peter" uniqKey="Hillemanns P" first="Peter" last="Hillemanns">Peter Hillemanns</name><affiliation><nlm:aff id="af37"><institution>Clinics of Obstetrics and Gynaecology</institution>,<addr-line>Hannover</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Dork, Thilo" sort="Dork, Thilo" uniqKey="Dork T" first="Thilo" last="Dörk">Thilo Dörk</name><affiliation><nlm:aff id="af37"><institution>Clinics of Obstetrics and Gynaecology</institution>,<addr-line>Hannover</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Nevanlinna, Heli A" sort="Nevanlinna, Heli A" uniqKey="Nevanlinna H" first="Heli A." last="Nevanlinna">Heli A. Nevanlinna</name><affiliation><nlm:aff id="af38"><addr-line>Department of Obstetrics and Gynecology</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Heikkinen, Tuomas" sort="Heikkinen, Tuomas" uniqKey="Heikkinen T" first="Tuomas" last="Heikkinen">Tuomas Heikkinen</name><affiliation><nlm:aff id="af38"><addr-line>Department of Obstetrics and Gynecology</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Heikkil, P Ivi" sort="Heikkil, P Ivi" uniqKey="Heikkil P" first="P Ivi" last="Heikkil">P Ivi Heikkil</name><affiliation><nlm:aff wicri:cut=" and" id="af40"><addr-line>Department of Pathology</addr-line></nlm:aff></affiliation></author><author><name sortKey="Blomqvist, Carl" sort="Blomqvist, Carl" uniqKey="Blomqvist C" first="Carl" last="Blomqvist">Carl Blomqvist</name><affiliation><nlm:aff id="af41"><addr-line>Department of Oncology</addr-line>,<institution>Helsinki University Central Hospital</institution>,<addr-line>Helsinki</addr-line>,<country>Finland</country>,</nlm:aff></affiliation></author><author><name sortKey="Aittom Ki, Kristiina" sort="Aittom Ki, Kristiina" uniqKey="Aittom Ki K" first="Kristiina" last="Aittom Ki">Kristiina Aittom Ki</name><affiliation><nlm:aff id="af39"><addr-line>Department of Clinical Genetics</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Aaltonen, Kirsimari" sort="Aaltonen, Kirsimari" uniqKey="Aaltonen K" first="Kirsimari" last="Aaltonen">Kirsimari Aaltonen</name><affiliation><nlm:aff id="af38"><addr-line>Department of Obstetrics and Gynecology</addr-line>,</nlm:aff></affiliation><affiliation><nlm:aff id="af41"><addr-line>Department of Oncology</addr-line>,<institution>Helsinki University Central Hospital</institution>,<addr-line>Helsinki</addr-line>,<country>Finland</country>,</nlm:aff></affiliation></author><author><name sortKey="Lindblom, Annika" sort="Lindblom, Annika" uniqKey="Lindblom A" first="Annika" last="Lindblom">Annika Lindblom</name><affiliation><nlm:aff id="af42"><addr-line>Department of Molecular Medicine and Surgery,</addr-line></nlm:aff></affiliation></author><author><name sortKey="Margolin, Sara" sort="Margolin, Sara" uniqKey="Margolin S" first="Sara" last="Margolin">Sara Margolin</name><affiliation><nlm:aff wicri:cut=" and" id="af43"><addr-line>Department of Oncology and Pathology</addr-line></nlm:aff></affiliation></author><author><name sortKey="Mannermaa, Arto" sort="Mannermaa, Arto" uniqKey="Mannermaa A" first="Arto" last="Mannermaa">Arto Mannermaa</name><affiliation><nlm:aff id="af45"><addr-line>Department of Pathology</addr-line>,<institution>Institute of Clinical Medicine, University of Eastern Finland and Kuopio University Hospital</institution>, Kuopio,<country>Finland</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af46"><institution>Biocenter Kuopio</institution>,<addr-line>Kuopio</addr-line>,<country>Finland</country>,</nlm:aff></affiliation></author><author><name sortKey="Kosma, Veli Matti" sort="Kosma, Veli Matti" uniqKey="Kosma V" first="Veli-Matti" last="Kosma">Veli-Matti Kosma</name><affiliation><nlm:aff id="af45"><addr-line>Department of Pathology</addr-line>,<institution>Institute of Clinical Medicine, University of Eastern Finland and Kuopio University Hospital</institution>, Kuopio,<country>Finland</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af46"><institution>Biocenter Kuopio</institution>,<addr-line>Kuopio</addr-line>,<country>Finland</country>,</nlm:aff></affiliation></author><author><name sortKey="Kauppinen, Jaana M" sort="Kauppinen, Jaana M" uniqKey="Kauppinen J" first="Jaana M." last="Kauppinen">Jaana M. Kauppinen</name><affiliation><nlm:aff id="af45"><addr-line>Department of Pathology</addr-line>,<institution>Institute of Clinical Medicine, University of Eastern Finland and Kuopio University Hospital</institution>, Kuopio,<country>Finland</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af46"><institution>Biocenter Kuopio</institution>,<addr-line>Kuopio</addr-line>,<country>Finland</country>,</nlm:aff></affiliation></author><author><name sortKey="Kataja, Vesa" sort="Kataja, Vesa" uniqKey="Kataja V" first="Vesa" last="Kataja">Vesa Kataja</name><affiliation><nlm:aff id="af47"><addr-line>Department of Oncology</addr-line>,<institution>Vaasa Central Hospital</institution>,<addr-line>Vaasa</addr-line>,<country>Finland</country>,</nlm:aff></affiliation></author><author><name sortKey="Auvinen, P Ivi" sort="Auvinen, P Ivi" uniqKey="Auvinen P" first="P Ivi" last="Auvinen">P Ivi Auvinen</name><affiliation><nlm:aff wicri:cut=" and" id="af48"><addr-line>Department of Oncology</addr-line></nlm:aff></affiliation></author><author><name sortKey="Eskelinen, Matti" sort="Eskelinen, Matti" uniqKey="Eskelinen M" first="Matti" last="Eskelinen">Matti Eskelinen</name><affiliation><nlm:aff id="af49"><addr-line>Department of Surgery</addr-line>,<institution>Kuopio University Hospital</institution>,<addr-line>Kuopio</addr-line>,<country>Finland</country>,</nlm:aff></affiliation></author><author><name sortKey="Soini, Ylermi" sort="Soini, Ylermi" uniqKey="Soini Y" first="Ylermi" last="Soini">Ylermi Soini</name><affiliation><nlm:aff id="af45"><addr-line>Department of Pathology</addr-line>,<institution>Institute of Clinical Medicine, University of Eastern Finland and Kuopio University Hospital</institution>, Kuopio,<country>Finland</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af46"><institution>Biocenter Kuopio</institution>,<addr-line>Kuopio</addr-line>,<country>Finland</country>,</nlm:aff></affiliation></author><author><name sortKey="Chenevix Trench, Georgia" sort="Chenevix Trench, Georgia" uniqKey="Chenevix Trench G" first="Georgia" last="Chenevix-Trench">Georgia Chenevix-Trench</name><affiliation><nlm:aff id="af50"><institution>Queensland Institute of Medical Research</institution>,<addr-line>Brisbane</addr-line>,<country>Australia</country>,</nlm:aff></affiliation></author><author><name sortKey="Spurdle, Amanda B" sort="Spurdle, Amanda B" uniqKey="Spurdle A" first="Amanda B." last="Spurdle">Amanda B. Spurdle</name><affiliation><nlm:aff id="af50"><institution>Queensland Institute of Medical Research</institution>,<addr-line>Brisbane</addr-line>,<country>Australia</country>,</nlm:aff></affiliation></author><author><name sortKey="Beesley, Jonathan" sort="Beesley, Jonathan" uniqKey="Beesley J" first="Jonathan" last="Beesley">Jonathan Beesley</name><affiliation><nlm:aff id="af50"><institution>Queensland Institute of Medical Research</institution>,<addr-line>Brisbane</addr-line>,<country>Australia</country>,</nlm:aff></affiliation></author><author><name sortKey="Chen, Xiaoqing" sort="Chen, Xiaoqing" uniqKey="Chen X" first="Xiaoqing" last="Chen">Xiaoqing Chen</name><affiliation><nlm:aff id="af50"><institution>Queensland Institute of Medical Research</institution>,<addr-line>Brisbane</addr-line>,<country>Australia</country>,</nlm:aff></affiliation></author><author><name sortKey="Holland, Helene" sort="Holland, Helene" uniqKey="Holland H" first="Helene" last="Holland">Helene Holland</name><affiliation><nlm:aff id="af50"><institution>Queensland Institute of Medical Research</institution>,<addr-line>Brisbane</addr-line>,<country>Australia</country>,</nlm:aff></affiliation></author><author><name sortKey="Lambrechts, Diether" sort="Lambrechts, Diether" uniqKey="Lambrechts D" first="Diether" last="Lambrechts">Diether Lambrechts</name><affiliation><nlm:aff id="af52"><institution>Vesalius Research Center</institution>,<addr-line>KU Leuven and VIB, Leuven</addr-line>,<country>Belgium</country>,</nlm:aff></affiliation></author><author><name sortKey="Claes, Bart" sort="Claes, Bart" uniqKey="Claes B" first="Bart" last="Claes">Bart Claes</name><affiliation><nlm:aff id="af52"><institution>Vesalius Research Center</institution>,<addr-line>KU Leuven and VIB, Leuven</addr-line>,<country>Belgium</country>,</nlm:aff></affiliation></author><author><name sortKey="Vandorpe, Thijs" sort="Vandorpe, Thijs" uniqKey="Vandorpe T" first="Thijs" last="Vandorpe">Thijs Vandorpe</name><affiliation><nlm:aff id="af53"><addr-line>Multidisciplinary Breast Center</addr-line>,<institution>University Hospitals Leuven</institution>,<country>Belgium</country>,</nlm:aff></affiliation></author><author><name sortKey="Neven, Patrick" sort="Neven, Patrick" uniqKey="Neven P" first="Patrick" last="Neven">Patrick Neven</name><affiliation><nlm:aff id="af53"><addr-line>Multidisciplinary Breast Center</addr-line>,<institution>University Hospitals Leuven</institution>,<country>Belgium</country>,</nlm:aff></affiliation></author><author><name sortKey="Wildiers, Hans" sort="Wildiers, Hans" uniqKey="Wildiers H" first="Hans" last="Wildiers">Hans Wildiers</name><affiliation><nlm:aff id="af53"><addr-line>Multidisciplinary Breast Center</addr-line>,<institution>University Hospitals Leuven</institution>,<country>Belgium</country>,</nlm:aff></affiliation></author><author><name sortKey="Flesch Janys, Dieter" sort="Flesch Janys, Dieter" uniqKey="Flesch Janys D" first="Dieter" last="Flesch-Janys">Dieter Flesch-Janys</name><affiliation><nlm:aff id="af54"><addr-line>Institute for Medical Biometrics and Epidemiology</addr-line>,<institution>University Clinic Hamburg-Eppendorf</institution>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Hein, Rebecca" sort="Hein, Rebecca" uniqKey="Hein R" first="Rebecca" last="Hein">Rebecca Hein</name><affiliation><nlm:aff id="af18"><addr-line>Division of Cancer Epidemiology</addr-line>,<institution>German Cancer Research Center</institution>,<addr-line>Heidelberg</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Loning, Thomas" sort="Loning, Thomas" uniqKey="Loning T" first="Thomas" last="Löning">Thomas Löning</name><affiliation><nlm:aff id="af55"><addr-line>Albertinen Pathology Department, Hamburg</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Kosel, Matthew" sort="Kosel, Matthew" uniqKey="Kosel M" first="Matthew" last="Kosel">Matthew Kosel</name><affiliation><nlm:aff wicri:cut=" and" id="af5"><addr-line>Department of Laboratory Medicine and Pathology</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af6"><addr-line>Department of Health Sciences Research</addr-line>,<institution>Mayo Clinic</institution>,<addr-line>Rochester, MN</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Fredericksen, Zachary S" sort="Fredericksen, Zachary S" uniqKey="Fredericksen Z" first="Zachary S." last="Fredericksen">Zachary S. Fredericksen</name><affiliation><nlm:aff wicri:cut=" and" id="af5"><addr-line>Department of Laboratory Medicine and Pathology</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af6"><addr-line>Department of Health Sciences Research</addr-line>,<institution>Mayo Clinic</institution>,<addr-line>Rochester, MN</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Wang, Xianshu" sort="Wang, Xianshu" uniqKey="Wang X" first="Xianshu" last="Wang">Xianshu Wang</name><affiliation><nlm:aff wicri:cut=" and" id="af5"><addr-line>Department of Laboratory Medicine and Pathology</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af6"><addr-line>Department of Health Sciences Research</addr-line>,<institution>Mayo Clinic</institution>,<addr-line>Rochester, MN</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Giles, Graham G" sort="Giles, Graham G" uniqKey="Giles G" first="Graham G." last="Giles">Graham G. Giles</name><affiliation><nlm:aff id="af57"><addr-line>Cancer Epidemiology Centre</addr-line>,<institution>The Cancer Council Victoria</institution>,<addr-line>Melbourne</addr-line>,<country>Australia</country>,</nlm:aff></affiliation></author><author><name sortKey="Baglietto, Laura" sort="Baglietto, Laura" uniqKey="Baglietto L" first="Laura" last="Baglietto">Laura Baglietto</name><affiliation><nlm:aff id="af58"><addr-line>Department of Anatomical Pathology</addr-line>,<institution>Alfred Hospital</institution>,<addr-line>Melbourne</addr-line>,<country>Australia</country>,</nlm:aff></affiliation></author><author><name sortKey="Severi, Gianluca" sort="Severi, Gianluca" uniqKey="Severi G" first="Gianluca" last="Severi">Gianluca Severi</name><affiliation><nlm:aff id="af57"><addr-line>Cancer Epidemiology Centre</addr-line>,<institution>The Cancer Council Victoria</institution>,<addr-line>Melbourne</addr-line>,<country>Australia</country>,</nlm:aff></affiliation></author><author><name sortKey="Mclean, Catriona" sort="Mclean, Catriona" uniqKey="Mclean C" first="Catriona" last="Mclean">Catriona Mclean</name><affiliation><nlm:aff id="af58"><addr-line>Department of Anatomical Pathology</addr-line>,<institution>Alfred Hospital</institution>,<addr-line>Melbourne</addr-line>,<country>Australia</country>,</nlm:aff></affiliation></author><author><name sortKey="Haiman, Christopher A" sort="Haiman, Christopher A" uniqKey="Haiman C" first="Christopher A." last="Haiman">Christopher A. Haiman</name><affiliation><nlm:aff id="af59"><addr-line>Department of Preventive Medicine, Keck School of Medicine and Norris Comprehensive Cancer Center</addr-line>,<institution>University of Southern California</institution>,<addr-line>Los Angeles, CA 90089</addr-line>, USA,</nlm:aff></affiliation></author><author><name sortKey="Henderson, Brian E" sort="Henderson, Brian E" uniqKey="Henderson B" first="Brian E." last="Henderson">Brian E. Henderson</name><affiliation><nlm:aff id="af59"><addr-line>Department of Preventive Medicine, Keck School of Medicine and Norris Comprehensive Cancer Center</addr-line>,<institution>University of Southern California</institution>,<addr-line>Los Angeles, CA 90089</addr-line>, USA,</nlm:aff></affiliation></author><author><name sortKey="Le Marchand, Loic" sort="Le Marchand, Loic" uniqKey="Le Marchand L" first="Loic" last="Le Marchand">Loic Le Marchand</name><affiliation><nlm:aff id="af60"><addr-line>Epidemiology Program</addr-line>,<institution>Cancer Research Center, University of Hawaii</institution>,<addr-line>Honolulu, HI 96813</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Kolonel, Laurence N" sort="Kolonel, Laurence N" uniqKey="Kolonel L" first="Laurence N." last="Kolonel">Laurence N. Kolonel</name><affiliation><nlm:aff id="af60"><addr-line>Epidemiology Program</addr-line>,<institution>Cancer Research Center, University of Hawaii</institution>,<addr-line>Honolulu, HI 96813</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Grenaker Aln S, Grethe" sort="Grenaker Aln S, Grethe" uniqKey="Grenaker Aln S G" first="Grethe" last="Grenaker Aln S">Grethe Grenaker Aln S</name><affiliation><nlm:aff id="af61"><addr-line>Department of Genetics</addr-line>,<institution>Institute for Cancer Research, Oslo University Hospital</institution>,<addr-line>Radiumhospitalet, Montebello 0310, Oslo</addr-line>,<country>Norway</country>,</nlm:aff></affiliation></author><author><name sortKey="Kristensen, Vessela" sort="Kristensen, Vessela" uniqKey="Kristensen V" first="Vessela" last="Kristensen">Vessela Kristensen</name><affiliation><nlm:aff id="af61"><addr-line>Department of Genetics</addr-line>,<institution>Institute for Cancer Research, Oslo University Hospital</institution>,<addr-line>Radiumhospitalet, Montebello 0310, Oslo</addr-line>,<country>Norway</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af62"><addr-line>Faculty of Medicine</addr-line><institution>(Faculty Division Ahus)</institution>,<addr-line>UiO</addr-line>,<country>Norway</country>,</nlm:aff></affiliation></author><author><name sortKey="B Rresen Dale, Anne Lise" sort="B Rresen Dale, Anne Lise" uniqKey="B Rresen Dale A" first="Anne-Lise" last="B Rresen-Dale">Anne-Lise B Rresen-Dale</name><affiliation><nlm:aff id="af61"><addr-line>Department of Genetics</addr-line>,<institution>Institute for Cancer Research, Oslo University Hospital</institution>,<addr-line>Radiumhospitalet, Montebello 0310, Oslo</addr-line>,<country>Norway</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af62"><addr-line>Faculty of Medicine</addr-line><institution>(Faculty Division Ahus)</institution>,<addr-line>UiO</addr-line>,<country>Norway</country>,</nlm:aff></affiliation></author><author><name sortKey="Hunter, David J" sort="Hunter, David J" uniqKey="Hunter D" first="David J." last="Hunter">David J. Hunter</name><affiliation><nlm:aff id="af63"><addr-line>Channing Laboratory, Department of Medicine</addr-line>,<institution>Brigham and Womens Hospital and Harvard Medical school</institution>, Boston, MA, USA,</nlm:aff></affiliation><affiliation><nlm:aff id="af64"><addr-line>Department of Epidemiology</addr-line>,<institution>Harvard school of public health</institution>,<addr-line>Boston, MA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Hankinson, Susan E" sort="Hankinson, Susan E" uniqKey="Hankinson S" first="Susan E." last="Hankinson">Susan E. Hankinson</name><affiliation><nlm:aff id="af63"><addr-line>Channing Laboratory, Department of Medicine</addr-line>,<institution>Brigham and Womens Hospital and Harvard Medical school</institution>, Boston, MA, USA,</nlm:aff></affiliation><affiliation><nlm:aff id="af64"><addr-line>Department of Epidemiology</addr-line>,<institution>Harvard school of public health</institution>,<addr-line>Boston, MA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L." last="Andrulis">Irene L. Andrulis</name><affiliation><nlm:aff id="af65"><institution>Samuel Lunenfeld Research Institute, Mount Sinai Hospital</institution>,<addr-line>Ontario Cancer Genetics Network, Cancer Care Ontario, Ontario</addr-line>,<country>Canada</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af66"><addr-line>Department of Molecular Genetics and</addr-line></nlm:aff></affiliation><affiliation><nlm:aff wicri:cut=" and" id="af67"><addr-line>Laboratory Medicine</addr-line><addr-line>Pathobiology</addr-line>,<institution>University of Toronto</institution>,<addr-line>Toronto, Ontario</addr-line>,<country>Canada</country>,</nlm:aff></affiliation></author><author><name sortKey="Marie Mulligan, Anna" sort="Marie Mulligan, Anna" uniqKey="Marie Mulligan A" first="Anna" last="Marie Mulligan">Anna Marie Mulligan</name><affiliation><nlm:aff wicri:cut=" and" id="af67"><addr-line>Laboratory Medicine</addr-line><addr-line>Pathobiology</addr-line>,<institution>University of Toronto</institution>,<addr-line>Toronto, Ontario</addr-line>,<country>Canada</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af68"><addr-line>Keenan Research Centre</addr-line>,<institution>Li Ka Shing Knowledge Institute of St Michael's Hospital</institution>,<addr-line>Toronto, Ontario</addr-line>,<country>Canada</country>,</nlm:aff></affiliation></author><author><name sortKey="O Malley, Frances P" sort="O Malley, Frances P" uniqKey="O Malley F" first="Frances P." last="O'Malley">Frances P. O'Malley</name><affiliation><nlm:aff wicri:cut=" and" id="af67"><addr-line>Laboratory Medicine</addr-line><addr-line>Pathobiology</addr-line>,<institution>University of Toronto</institution>,<addr-line>Toronto, Ontario</addr-line>,<country>Canada</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af69"><addr-line>The Department of Laboratory Medicine and the</addr-line><institution>Keenan Research Centre of the Li Ka Shing Knowledge Institute, St Michael's Hospital,</institution><addr-line>Toronto, Ontario</addr-line>,<country>Canada</country></nlm:aff></affiliation></author><author><name sortKey="Devilee, Peter" sort="Devilee, Peter" uniqKey="Devilee P" first="Peter" last="Devilee">Peter Devilee</name><affiliation><nlm:aff id="af70"><addr-line>Department Human Genetics & Department of Pathology</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Huijts, Petra E A" sort="Huijts, Petra E A" uniqKey="Huijts P" first="Petra E. A." last="Huijts">Petra E. A. Huijts</name><affiliation><nlm:aff wicri:cut=" and" id="af71"><addr-line>Clinical Genetics</addr-line></nlm:aff></affiliation></author><author><name sortKey="Tollenaar, Rob A E M" sort="Tollenaar, Rob A E M" uniqKey="Tollenaar R" first="Rob A. E. M." last="Tollenaar">Rob A. E. M. Tollenaar</name><affiliation><nlm:aff id="af72"><addr-line>Surgical Oncology</addr-line>,<institution>Leiden University Medical Center</institution>,<addr-line>Leiden</addr-line>,<country>The Netherlands</country>,</nlm:aff></affiliation></author><author><name sortKey="Van Asperen, Christi J" sort="Van Asperen, Christi J" uniqKey="Van Asperen C" first="Christi J." last="Van Asperen">Christi J. Van Asperen</name><affiliation><nlm:aff wicri:cut=" and" id="af71"><addr-line>Clinical Genetics</addr-line></nlm:aff></affiliation></author><author><name sortKey="Seynaeve, Caroline S" sort="Seynaeve, Caroline S" uniqKey="Seynaeve C" first="Caroline S." last="Seynaeve">Caroline S. Seynaeve</name><affiliation><nlm:aff id="af73"><addr-line>Department of Medical Oncology</addr-line>,<institution>Rotterdam Family Cancer Clinic, Erasmus MC-Daniel den Hoed Cancer Center</institution>,<addr-line>Rotterdam</addr-line>,<country>The Netherlands</country>,</nlm:aff></affiliation></author><author><name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J." last="Chanock">Stephen J. Chanock</name><affiliation><nlm:aff id="af74"><addr-line>Advanced Technology Center</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Gaithersburg, MD 20892-4605</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Lissowska, Jolanta" sort="Lissowska, Jolanta" uniqKey="Lissowska J" first="Jolanta" last="Lissowska">Jolanta Lissowska</name><affiliation><nlm:aff id="af75"><addr-line>Department of Cancer Epidemiology and Prevention</addr-line>,<institution>Cancer Center and M. Sklodowska-Curie Institute of Oncology</institution>,<addr-line>02-781 Warsaw</addr-line>,<country>Poland</country>,</nlm:aff></affiliation></author><author><name sortKey="Brinton, Louise" sort="Brinton, Louise" uniqKey="Brinton L" first="Louise" last="Brinton">Louise Brinton</name><affiliation><nlm:aff id="af76"><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Rockville, MD 20852-7234</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Peplonska, Beata" sort="Peplonska, Beata" uniqKey="Peplonska B" first="Beata" last="Peplonska">Beata Peplonska</name><affiliation><nlm:aff id="af77"><institution>Nofer Institute of Occupational Medicine</institution>,<addr-line>91-348 Lodz</addr-line>,<country>Poland</country>,</nlm:aff></affiliation></author><author><name sortKey="Figueroa, Jonine" sort="Figueroa, Jonine" uniqKey="Figueroa J" first="Jonine" last="Figueroa">Jonine Figueroa</name><affiliation><nlm:aff id="af4"><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Rockville, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Yang, Xiaohong R" sort="Yang, Xiaohong R" uniqKey="Yang X" first="Xiaohong R." last="Yang">Xiaohong R. Yang</name><affiliation><nlm:aff id="af4"><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Rockville, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Hooning, Maartje J" sort="Hooning, Maartje J" uniqKey="Hooning M" first="Maartje J." last="Hooning">Maartje J. Hooning</name><affiliation><nlm:aff id="af78"><addr-line>Department of Medical Oncology</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Hollestelle, Antoinette" sort="Hollestelle, Antoinette" uniqKey="Hollestelle A" first="Antoinette" last="Hollestelle">Antoinette Hollestelle</name><affiliation><nlm:aff id="af78"><addr-line>Department of Medical Oncology</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Oldenburg, Rogier A" sort="Oldenburg, Rogier A" uniqKey="Oldenburg R" first="Rogier A." last="Oldenburg">Rogier A. Oldenburg</name><affiliation><nlm:aff wicri:cut=" and" id="af79"><addr-line>Department of Clinical Genetics</addr-line></nlm:aff></affiliation></author><author><name sortKey="Jager, Agnes" sort="Jager, Agnes" uniqKey="Jager A" first="Agnes" last="Jager">Agnes Jager</name><affiliation><nlm:aff id="af78"><addr-line>Department of Medical Oncology</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Kriege, Mieke" sort="Kriege, Mieke" uniqKey="Kriege M" first="Mieke" last="Kriege">Mieke Kriege</name><affiliation><nlm:aff id="af78"><addr-line>Department of Medical Oncology</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Ozturk, Bahar" sort="Ozturk, Bahar" uniqKey="Ozturk B" first="Bahar" last="Ozturk">Bahar Ozturk</name><affiliation><nlm:aff id="af78"><addr-line>Department of Medical Oncology</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Van Leenders, Geert J L H" sort="Van Leenders, Geert J L H" uniqKey="Van Leenders G" first="Geert J. L. H." last="Van Leenders">Geert J. L. H. Van Leenders</name><affiliation><nlm:aff id="af80"><addr-line>Department of Pathology</addr-line>,<institution>Rotterdam Family Cancer Clinic, Erasmus University Medical Center</institution>,<addr-line>Rotterdam</addr-line>,<country>the Netherlands</country>,</nlm:aff></affiliation></author><author><name sortKey="Hall, Per" sort="Hall, Per" uniqKey="Hall P" first="Per" last="Hall">Per Hall</name><affiliation><nlm:aff id="af44"><addr-line>Department of Medical Epidemiology and Biostatistics</addr-line>,<institution>Karolinska Institute</institution>,<addr-line>Stockholm</addr-line>,<country>Sweden</country>,</nlm:aff></affiliation></author><author><name sortKey="Czene, Kamila" sort="Czene, Kamila" uniqKey="Czene K" first="Kamila" last="Czene">Kamila Czene</name><affiliation><nlm:aff id="af44"><addr-line>Department of Medical Epidemiology and Biostatistics</addr-line>,<institution>Karolinska Institute</institution>,<addr-line>Stockholm</addr-line>,<country>Sweden</country>,</nlm:aff></affiliation></author><author><name sortKey="Humphreys, Keith" sort="Humphreys, Keith" uniqKey="Humphreys K" first="Keith" last="Humphreys">Keith Humphreys</name><affiliation><nlm:aff id="af44"><addr-line>Department of Medical Epidemiology and Biostatistics</addr-line>,<institution>Karolinska Institute</institution>,<addr-line>Stockholm</addr-line>,<country>Sweden</country>,</nlm:aff></affiliation></author><author><name sortKey="Liu, Jianjun" sort="Liu, Jianjun" uniqKey="Liu J" first="Jianjun" last="Liu">Jianjun Liu</name><affiliation><nlm:aff id="af81"><addr-line>Human Genetics Laboratory</addr-line>,<institution>Genome Institute of Singapore</institution>,<country>Singapore</country>,</nlm:aff></affiliation></author><author><name sortKey="Cox, Angela" sort="Cox, Angela" uniqKey="Cox A" first="Angela" last="Cox">Angela Cox</name><affiliation><nlm:aff id="af82"><addr-line>Department of Oncology, Institute for Cancer Studies</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Connley, Daniel" sort="Connley, Daniel" uniqKey="Connley D" first="Daniel" last="Connley">Daniel Connley</name><affiliation><nlm:aff id="af82"><addr-line>Department of Oncology, Institute for Cancer Studies</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Cramp, Helen E" sort="Cramp, Helen E" uniqKey="Cramp H" first="Helen E." last="Cramp">Helen E. Cramp</name><affiliation><nlm:aff id="af82"><addr-line>Department of Oncology, Institute for Cancer Studies</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Cross, Simon S" sort="Cross, Simon S" uniqKey="Cross S" first="Simon S." last="Cross">Simon S. Cross</name><affiliation><nlm:aff wicri:cut=" and" id="af83"><addr-line>Academic Unit of Pathology, Department of Oncology</addr-line></nlm:aff></affiliation></author><author><name sortKey="Balasubramanian, Sabapathy P" sort="Balasubramanian, Sabapathy P" uniqKey="Balasubramanian S" first="Sabapathy P." last="Balasubramanian">Sabapathy P. Balasubramanian</name><affiliation><nlm:aff id="af84"><addr-line>Academic Unit of Surgical Oncology, Department of Oncology</addr-line>,<institution>University of Sheffield Medical School</institution>,<addr-line>Sheffield</addr-line>,<country>UK</country>,</nlm:aff></affiliation></author><author><name sortKey="Reed, Malcolm W R" sort="Reed, Malcolm W R" uniqKey="Reed M" first="Malcolm W. R." last="Reed">Malcolm W. R. Reed</name><affiliation><nlm:aff id="af84"><addr-line>Academic Unit of Surgical Oncology, Department of Oncology</addr-line>,<institution>University of Sheffield Medical School</institution>,<addr-line>Sheffield</addr-line>,<country>UK</country>,</nlm:aff></affiliation></author><author><name sortKey="Dunning, Alison M" sort="Dunning, Alison M" uniqKey="Dunning A" first="Alison M." last="Dunning">Alison M. Dunning</name><affiliation><nlm:aff wicri:cut=" and" id="af85"><addr-line>Department of Oncology</addr-line></nlm:aff></affiliation></author><author><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F." last="Easton">Douglas F. Easton</name><affiliation><nlm:aff id="af86"><addr-line>Department of Public Health and Primary Care</addr-line>,<institution>University of Cambridge</institution>,<addr-line>Cambridge</addr-line>,<country>UK</country>,</nlm:aff></affiliation></author><author><name sortKey="Humphreys, Manjeet K" sort="Humphreys, Manjeet K" uniqKey="Humphreys M" first="Manjeet K." last="Humphreys">Manjeet K. Humphreys</name><affiliation><nlm:aff id="af86"><addr-line>Department of Public Health and Primary Care</addr-line>,<institution>University of Cambridge</institution>,<addr-line>Cambridge</addr-line>,<country>UK</country>,</nlm:aff></affiliation></author><author><name sortKey="Caldas, Carlos" sort="Caldas, Carlos" uniqKey="Caldas C" first="Carlos" last="Caldas">Carlos Caldas</name><affiliation><nlm:aff wicri:cut=" and" id="af85"><addr-line>Department of Oncology</addr-line></nlm:aff></affiliation></author><author><name sortKey="Blows, Fiona" sort="Blows, Fiona" uniqKey="Blows F" first="Fiona" last="Blows">Fiona Blows</name><affiliation><nlm:aff wicri:cut=" and" id="af85"><addr-line>Department of Oncology</addr-line></nlm:aff></affiliation></author><author><name sortKey="Driver, Kristy" sort="Driver, Kristy" uniqKey="Driver K" first="Kristy" last="Driver">Kristy Driver</name><affiliation><nlm:aff wicri:cut=" and" id="af85"><addr-line>Department of Oncology</addr-line></nlm:aff></affiliation></author><author><name sortKey="Provenzano, Elena" sort="Provenzano, Elena" uniqKey="Provenzano E" first="Elena" last="Provenzano">Elena Provenzano</name><affiliation><nlm:aff wicri:cut=" and" id="af85"><addr-line>Department of Oncology</addr-line></nlm:aff></affiliation></author><author><name sortKey="Lubinski, Jan" sort="Lubinski, Jan" uniqKey="Lubinski J" first="Jan" last="Lubinski">Jan Lubinski</name><affiliation><nlm:aff id="af87"><addr-line>Department of Genetics and Pathology</addr-line>,<institution>International Hereditary Cancer Center, Pomeranian Medical University</institution>,<addr-line>Szczecin</addr-line>,<country>Poland</country>,</nlm:aff></affiliation></author><author><name sortKey="Jakubowska, Anna" sort="Jakubowska, Anna" uniqKey="Jakubowska A" first="Anna" last="Jakubowska">Anna Jakubowska</name><affiliation><nlm:aff id="af87"><addr-line>Department of Genetics and Pathology</addr-line>,<institution>International Hereditary Cancer Center, Pomeranian Medical University</institution>,<addr-line>Szczecin</addr-line>,<country>Poland</country>,</nlm:aff></affiliation></author><author><name sortKey="Huzarski, Tomasz" sort="Huzarski, Tomasz" uniqKey="Huzarski T" first="Tomasz" last="Huzarski">Tomasz Huzarski</name><affiliation><nlm:aff id="af87"><addr-line>Department of Genetics and Pathology</addr-line>,<institution>International Hereditary Cancer Center, Pomeranian Medical University</institution>,<addr-line>Szczecin</addr-line>,<country>Poland</country>,</nlm:aff></affiliation></author><author><name sortKey="Byrski, Tomasz" sort="Byrski, Tomasz" uniqKey="Byrski T" first="Tomasz" last="Byrski">Tomasz Byrski</name><affiliation><nlm:aff id="af87"><addr-line>Department of Genetics and Pathology</addr-line>,<institution>International Hereditary Cancer Center, Pomeranian Medical University</institution>,<addr-line>Szczecin</addr-line>,<country>Poland</country>,</nlm:aff></affiliation></author><author><name sortKey="Cybulski, Cezary" sort="Cybulski, Cezary" uniqKey="Cybulski C" first="Cezary" last="Cybulski">Cezary Cybulski</name><affiliation><nlm:aff id="af87"><addr-line>Department of Genetics and Pathology</addr-line>,<institution>International Hereditary Cancer Center, Pomeranian Medical University</institution>,<addr-line>Szczecin</addr-line>,<country>Poland</country>,</nlm:aff></affiliation></author><author><name sortKey="Gorski, Bohdan" sort="Gorski, Bohdan" uniqKey="Gorski B" first="Bohdan" last="Gorski">Bohdan Gorski</name><affiliation><nlm:aff id="af87"><addr-line>Department of Genetics and Pathology</addr-line>,<institution>International Hereditary Cancer Center, Pomeranian Medical University</institution>,<addr-line>Szczecin</addr-line>,<country>Poland</country>,</nlm:aff></affiliation></author><author><name sortKey="Gronwald, Jacek" sort="Gronwald, Jacek" uniqKey="Gronwald J" first="Jacek" last="Gronwald">Jacek Gronwald</name><affiliation><nlm:aff id="af87"><addr-line>Department of Genetics and Pathology</addr-line>,<institution>International Hereditary Cancer Center, Pomeranian Medical University</institution>,<addr-line>Szczecin</addr-line>,<country>Poland</country>,</nlm:aff></affiliation></author><author><name sortKey="Brennan, Paul" sort="Brennan, Paul" uniqKey="Brennan P" first="Paul" last="Brennan">Paul Brennan</name><affiliation><nlm:aff id="af88"><institution>International agency for Research on Cancer</institution>,<addr-line>Lyon</addr-line>,<country>France</country>,</nlm:aff></affiliation></author><author><name sortKey="Sangrajrang, Suleeporn" sort="Sangrajrang, Suleeporn" uniqKey="Sangrajrang S" first="Suleeporn" last="Sangrajrang">Suleeporn Sangrajrang</name><affiliation><nlm:aff id="af89"><institution>National Cancer Institute</institution>,<addr-line>Bangkok</addr-line>,<country>Thailand</country>,</nlm:aff></affiliation></author><author><name sortKey="Gaborieau, Valerie" sort="Gaborieau, Valerie" uniqKey="Gaborieau V" first="Valerie" last="Gaborieau">Valerie Gaborieau</name><affiliation><nlm:aff id="af88"><institution>International agency for Research on Cancer</institution>,<addr-line>Lyon</addr-line>,<country>France</country>,</nlm:aff></affiliation></author><author><name sortKey="Shen, Chen Yang" sort="Shen, Chen Yang" uniqKey="Shen C" first="Chen-Yang" last="Shen">Chen-Yang Shen</name><affiliation><nlm:aff id="af90"><institution>Institute of Biomedical Sciences, Academia Sinica</institution>,<addr-line>Taipei</addr-line>,<country>Taiwan</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af91"><addr-line>Graduate Institute of Environmental Science</addr-line>,<institution>China Medical University</institution>,<addr-line>Taichung</addr-line>,<country>Taiwan</country>,</nlm:aff></affiliation></author><author><name sortKey="Hsiung, Chia Ni" sort="Hsiung, Chia Ni" uniqKey="Hsiung C" first="Chia-Ni" last="Hsiung">Chia-Ni Hsiung</name><affiliation><nlm:aff id="af90"><institution>Institute of Biomedical Sciences, Academia Sinica</institution>,<addr-line>Taipei</addr-line>,<country>Taiwan</country>,</nlm:aff></affiliation></author><author><name sortKey="Yu, Jyh Cherng" sort="Yu, Jyh Cherng" uniqKey="Yu J" first="Jyh-Cherng" last="Yu">Jyh-Cherng Yu</name><affiliation><nlm:aff wicri:cut=" and" id="af92"><addr-line>Department of Surgery</addr-line></nlm:aff></affiliation></author><author><name sortKey="Chen, Shou Tung" sort="Chen, Shou Tung" uniqKey="Chen S" first="Shou-Tung" last="Chen">Shou-Tung Chen</name><affiliation><nlm:aff id="af94"><addr-line>Department of Surgery</addr-line>,<institution>Changhua Christian Hospital</institution>,<addr-line>Changhua</addr-line>, Taiwan,</nlm:aff></affiliation></author><author><name sortKey="Hsu, Giu Cheng" sort="Hsu, Giu Cheng" uniqKey="Hsu G" first="Giu-Cheng" last="Hsu">Giu-Cheng Hsu</name><affiliation><nlm:aff id="af93"><addr-line>Department of Radiology</addr-line>,<institution>Tri-Service General Hospital</institution>,<addr-line>Taipei</addr-line>, Taiwan,</nlm:aff></affiliation></author><author><name sortKey="Hou, Ming Feng" sort="Hou, Ming Feng" uniqKey="Hou M" first="Ming-Feng" last="Hou">Ming-Feng Hou</name><affiliation><nlm:aff id="af95"><addr-line>Department of Surgery</addr-line>,<institution>Kaohsiung Medical University Hospital</institution>,<addr-line>Kaohsiung</addr-line>, Taiwan,</nlm:aff></affiliation></author><author><name sortKey="Huang, Chiun Sheng" sort="Huang, Chiun Sheng" uniqKey="Huang C" first="Chiun-Sheng" last="Huang">Chiun-Sheng Huang</name><affiliation><nlm:aff id="af96"><addr-line>Department of Surgery</addr-line>,<institution>National Taiwan University Hospital</institution>,<addr-line>Taipei</addr-line>,<country>Taiwan</country>,</nlm:aff></affiliation></author><author><name sortKey="Anton Culver, Hoda" sort="Anton Culver, Hoda" uniqKey="Anton Culver H" first="Hoda" last="Anton-Culver">Hoda Anton-Culver</name><affiliation><nlm:aff id="af97"><addr-line>Department of Epidemiology</addr-line>,<institution>University of California at Irvine</institution>,<addr-line>Irvine, CA 92697</addr-line>,<country>USA</country></nlm:aff></affiliation></author><author><name sortKey="Ziogas, Argyrios" sort="Ziogas, Argyrios" uniqKey="Ziogas A" first="Argyrios" last="Ziogas">Argyrios Ziogas</name><affiliation><nlm:aff id="af97"><addr-line>Department of Epidemiology</addr-line>,<institution>University of California at Irvine</institution>,<addr-line>Irvine, CA 92697</addr-line>,<country>USA</country></nlm:aff></affiliation></author><author><name sortKey="Pharoah, Paul D P" sort="Pharoah, Paul D P" uniqKey="Pharoah P" first="Paul D. P." last="Pharoah">Paul D. P. Pharoah</name><affiliation><nlm:aff wicri:cut=" and" id="af85"><addr-line>Department of Oncology</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af86"><addr-line>Department of Public Health and Primary Care</addr-line>,<institution>University of Cambridge</institution>,<addr-line>Cambridge</addr-line>,<country>UK</country>,</nlm:aff></affiliation></author><author><name sortKey="Garcia Closas, Montserrat" sort="Garcia Closas, Montserrat" uniqKey="Garcia Closas M" first="Montserrat" last="Garcia-Closas">Montserrat Garcia-Closas</name><affiliation><nlm:aff id="af4"><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Rockville, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation><affiliation><nlm:aff wicri:cut=" and" id="af85"><addr-line>Department of Oncology</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af86"><addr-line>Department of Public Health and Primary Care</addr-line>,<institution>University of Cambridge</institution>,<addr-line>Cambridge</addr-line>,<country>UK</country>,</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">21596841</idno><idno type="pmc">3140824</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140824</idno><idno type="RBID">PMC:3140824</idno><idno type="doi">10.1093/hmg/ddr228</idno><date when="2011">2011</date><idno type="wicri:Area/Pmc/Corpus">001881</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001881</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium</title><author><name sortKey="Broeks, Annegien" sort="Broeks, Annegien" uniqKey="Broeks A" first="Annegien" last="Broeks">Annegien Broeks</name><affiliation><nlm:aff id="af1"><addr-line>Department of Experimental Therapy</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Schmidt, Marjanka K" sort="Schmidt, Marjanka K" uniqKey="Schmidt M" first="Marjanka K." last="Schmidt">Marjanka K. Schmidt</name><affiliation><nlm:aff id="af1"><addr-line>Department of Experimental Therapy</addr-line>,</nlm:aff></affiliation><affiliation><nlm:aff wicri:cut=" and" id="af2"><addr-line>Department of Epidemiology</addr-line></nlm:aff></affiliation></author><author><name sortKey="Sherman, Mark E" sort="Sherman, Mark E" uniqKey="Sherman M" first="Mark E." last="Sherman">Mark E. Sherman</name><affiliation><nlm:aff id="af4"><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Rockville, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Couch, Fergus J" sort="Couch, Fergus J" uniqKey="Couch F" first="Fergus J." last="Couch">Fergus J. Couch</name><affiliation><nlm:aff wicri:cut=" and" id="af5"><addr-line>Department of Laboratory Medicine and Pathology</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af6"><addr-line>Department of Health Sciences Research</addr-line>,<institution>Mayo Clinic</institution>,<addr-line>Rochester, MN</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Hopper, John L" sort="Hopper, John L" uniqKey="Hopper J" first="John L." last="Hopper">John L. Hopper</name><affiliation><nlm:aff wicri:cut=" and" id="af7"><institution>Centre for Molecular, Environmental, Genetic and Analytic Epidemiology</institution></nlm:aff></affiliation></author><author><name sortKey="Dite, Gillian S" sort="Dite, Gillian S" uniqKey="Dite G" first="Gillian S." last="Dite">Gillian S. Dite</name><affiliation><nlm:aff wicri:cut=" and" id="af7"><institution>Centre for Molecular, Environmental, Genetic and Analytic Epidemiology</institution></nlm:aff></affiliation></author><author><name sortKey="Apicella, Carmel" sort="Apicella, Carmel" uniqKey="Apicella C" first="Carmel" last="Apicella">Carmel Apicella</name><affiliation><nlm:aff wicri:cut=" and" id="af7"><institution>Centre for Molecular, Environmental, Genetic and Analytic Epidemiology</institution></nlm:aff></affiliation></author><author><name sortKey="Smith, Letitia D" sort="Smith, Letitia D" uniqKey="Smith L" first="Letitia D." last="Smith">Letitia D. Smith</name><affiliation><nlm:aff id="af8"><addr-line>Genetic Epidemiology Laboratory, Department of Pathology</addr-line>,<institution>The University of Melbourne</institution>,<country>Australia</country>,</nlm:aff></affiliation></author><author><name sortKey="Hammet, Fleur" sort="Hammet, Fleur" uniqKey="Hammet F" first="Fleur" last="Hammet">Fleur Hammet</name><affiliation><nlm:aff id="af8"><addr-line>Genetic Epidemiology Laboratory, Department of Pathology</addr-line>,<institution>The University of Melbourne</institution>,<country>Australia</country>,</nlm:aff></affiliation></author><author><name sortKey="Southey, Melissa C" sort="Southey, Melissa C" uniqKey="Southey M" first="Melissa C." last="Southey">Melissa C. Southey</name><affiliation><nlm:aff id="af8"><addr-line>Genetic Epidemiology Laboratory, Department of Pathology</addr-line>,<institution>The University of Melbourne</institution>,<country>Australia</country>,</nlm:aff></affiliation></author><author><name sortKey="Van Veer, Laura J" sort="Van Veer, Laura J" uniqKey="Van Veer L" first="Laura J." last="Van Veer">Laura J. Van Veer</name><affiliation><nlm:aff id="af1"><addr-line>Department of Experimental Therapy</addr-line>,</nlm:aff></affiliation><affiliation><nlm:aff id="af3"><addr-line>Department of Molecular Pathology</addr-line>,<institution>The Netherlands Cancer Institute</institution>,<addr-line>Amsterdam</addr-line>,<country>the Netherlands</country>,</nlm:aff></affiliation></author><author><name sortKey="De Groot, Renate" sort="De Groot, Renate" uniqKey="De Groot R" first="Renate" last="De Groot">Renate De Groot</name><affiliation><nlm:aff id="af3"><addr-line>Department of Molecular Pathology</addr-line>,<institution>The Netherlands Cancer Institute</institution>,<addr-line>Amsterdam</addr-line>,<country>the Netherlands</country>,</nlm:aff></affiliation></author><author><name sortKey="Smit, Vincent T H B M" sort="Smit, Vincent T H B M" uniqKey="Smit V" first="Vincent T. H. B. M." last="Smit">Vincent T. H. B. M. Smit</name><affiliation><nlm:aff id="af9"><addr-line>Department of Pathology</addr-line>,<institution>Leiden University Medical Centre</institution>,<addr-line>Leiden</addr-line>,<country>the Netherlands</country>,</nlm:aff></affiliation></author><author><name sortKey="Fasching, Peter A" sort="Fasching, Peter A" uniqKey="Fasching P" first="Peter A." last="Fasching">Peter A. Fasching</name><affiliation><nlm:aff id="af10"><addr-line>Division of Hematology and Oncology, David Geffen School of Medicine</addr-line>,<institution>University of California at Los Angeles</institution>,<addr-line>Los Angeles, CA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Beckmann, Matthias W" sort="Beckmann, Matthias W" uniqKey="Beckmann M" first="Matthias W." last="Beckmann">Matthias W. Beckmann</name><affiliation><nlm:aff id="af11"><addr-line>Department of Gynecology and Obstetrics</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Jud, Sebastian" sort="Jud, Sebastian" uniqKey="Jud S" first="Sebastian" last="Jud">Sebastian Jud</name><affiliation><nlm:aff id="af11"><addr-line>Department of Gynecology and Obstetrics</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Ekici, Arif B" sort="Ekici, Arif B" uniqKey="Ekici A" first="Arif B." last="Ekici">Arif B. Ekici</name><affiliation><nlm:aff id="af14"><addr-line>Institute of Human Genetics</addr-line>,<institution>Friedrich Alexander University Erlangen</institution>,<addr-line>Nürnberg</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Hartmann, Arndt" sort="Hartmann, Arndt" uniqKey="Hartmann A" first="Arndt" last="Hartmann">Arndt Hartmann</name><affiliation><nlm:aff id="af12"><addr-line>Institute of Pathology</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Hein, Alexander" sort="Hein, Alexander" uniqKey="Hein A" first="Alexander" last="Hein">Alexander Hein</name><affiliation><nlm:aff id="af11"><addr-line>Department of Gynecology and Obstetrics</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Schulz Wendtland, Ruediger" sort="Schulz Wendtland, Ruediger" uniqKey="Schulz Wendtland R" first="Ruediger" last="Schulz-Wendtland">Ruediger Schulz-Wendtland</name><affiliation><nlm:aff id="af13"><addr-line>Institute of Radiology</addr-line>,<institution>University Breast Center</institution>,<institution>University Hospital Erlangen</institution>,<addr-line>Erlangen</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Burwinkel, Barbara" sort="Burwinkel, Barbara" uniqKey="Burwinkel B" first="Barbara" last="Burwinkel">Barbara Burwinkel</name><affiliation><nlm:aff wicri:cut=" and" id="af15"><addr-line>Department of Gynecology and Obstetrics</addr-line></nlm:aff></affiliation><affiliation><nlm:aff wicri:cut=" and" id="af17"><addr-line>Molecular Epidemiology</addr-line></nlm:aff></affiliation></author><author><name sortKey="Marme, Frederik" sort="Marme, Frederik" uniqKey="Marme F" first="Frederik" last="Marme">Frederik Marme</name><affiliation><nlm:aff wicri:cut=" and" id="af15"><addr-line>Department of Gynecology and Obstetrics</addr-line></nlm:aff></affiliation></author><author><name sortKey="Schneeweiss, Andreas" sort="Schneeweiss, Andreas" uniqKey="Schneeweiss A" first="Andreas" last="Schneeweiss">Andreas Schneeweiss</name><affiliation><nlm:aff wicri:cut=" and" id="af15"><addr-line>Department of Gynecology and Obstetrics</addr-line></nlm:aff></affiliation></author><author><name sortKey="Sinn, Hans Peter" sort="Sinn, Hans Peter" uniqKey="Sinn H" first="Hans-Peter" last="Sinn">Hans-Peter Sinn</name><affiliation><nlm:aff id="af16"><addr-line>Department of Pathology</addr-line>,<institution>University Hospital Heidelberg</institution>,<addr-line>Heidelberg</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Sohn, Christof" sort="Sohn, Christof" uniqKey="Sohn C" first="Christof" last="Sohn">Christof Sohn</name><affiliation><nlm:aff wicri:cut=" and" id="af15"><addr-line>Department of Gynecology and Obstetrics</addr-line></nlm:aff></affiliation></author><author><name sortKey="Tchatchou, Sandrine" sort="Tchatchou, Sandrine" uniqKey="Tchatchou S" first="Sandrine" last="Tchatchou">Sandrine Tchatchou</name><affiliation><nlm:aff wicri:cut=" and" id="af15"><addr-line>Department of Gynecology and Obstetrics</addr-line></nlm:aff></affiliation><affiliation><nlm:aff wicri:cut=" and" id="af17"><addr-line>Molecular Epidemiology</addr-line></nlm:aff></affiliation></author><author><name sortKey="Bojesen, Stig E" sort="Bojesen, Stig E" uniqKey="Bojesen S" first="Stig E." last="Bojesen">Stig E. Bojesen</name><affiliation><nlm:aff wicri:cut=" and" id="af19"><addr-line>Department of Clinical Biochemistry</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af20"><addr-line>Department of Breast Surgery</addr-line>,<institution>Herlev University Hospital</institution>,<institution>University of Copenhagen</institution>, Copenhagen,<country>Denmark</country>,</nlm:aff></affiliation></author><author><name sortKey="Nordestgaard, B Rge G" sort="Nordestgaard, B Rge G" uniqKey="Nordestgaard B" first="B Rge G." last="Nordestgaard">B Rge G. Nordestgaard</name><affiliation><nlm:aff wicri:cut=" and" id="af19"><addr-line>Department of Clinical Biochemistry</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af20"><addr-line>Department of Breast Surgery</addr-line>,<institution>Herlev University Hospital</institution>,<institution>University of Copenhagen</institution>, Copenhagen,<country>Denmark</country>,</nlm:aff></affiliation></author><author><name sortKey="Flyger, Henrik" sort="Flyger, Henrik" uniqKey="Flyger H" first="Henrik" last="Flyger">Henrik Flyger</name><affiliation><nlm:aff wicri:cut=" and" id="af19"><addr-line>Department of Clinical Biochemistry</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af20"><addr-line>Department of Breast Surgery</addr-line>,<institution>Herlev University Hospital</institution>,<institution>University of Copenhagen</institution>, Copenhagen,<country>Denmark</country>,</nlm:aff></affiliation></author><author><name sortKey=" Rsted, David D" sort=" Rsted, David D" uniqKey=" Rsted D" first="David D." last=" Rsted">David D. Rsted</name><affiliation><nlm:aff wicri:cut=" and" id="af19"><addr-line>Department of Clinical Biochemistry</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af20"><addr-line>Department of Breast Surgery</addr-line>,<institution>Herlev University Hospital</institution>,<institution>University of Copenhagen</institution>, Copenhagen,<country>Denmark</country>,</nlm:aff></affiliation></author><author><name sortKey="Kaur Knudsen, Diljit" sort="Kaur Knudsen, Diljit" uniqKey="Kaur Knudsen D" first="Diljit" last="Kaur-Knudsen">Diljit Kaur-Knudsen</name><affiliation><nlm:aff wicri:cut=" and" id="af19"><addr-line>Department of Clinical Biochemistry</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af20"><addr-line>Department of Breast Surgery</addr-line>,<institution>Herlev University Hospital</institution>,<institution>University of Copenhagen</institution>, Copenhagen,<country>Denmark</country>,</nlm:aff></affiliation></author><author><name sortKey="Milne, Roger L" sort="Milne, Roger L" uniqKey="Milne R" first="Roger L." last="Milne">Roger L. Milne</name><affiliation><nlm:aff wicri:cut=" and" id="af21"><addr-line>Genetic & Molecular Epidemiology Group</addr-line></nlm:aff></affiliation></author><author><name sortKey="Perez, Jose I Arias" sort="Perez, Jose I Arias" uniqKey="Perez J" first="Jose I. Arias" last="Pérez">Jose I. Arias Pérez</name><affiliation><nlm:aff wicri:cut=" and" id="af23"><addr-line>Servicio Cirugía General</addr-line></nlm:aff></affiliation></author><author><name sortKey="Zamora, Pilar" sort="Zamora, Pilar" uniqKey="Zamora P" first="Pilar" last="Zamora">Pilar Zamora</name><affiliation><nlm:aff id="af25"><addr-line>Servicio de Oncología Médica</addr-line>,<institution>Hospital La Paz</institution>,<addr-line>Madrid</addr-line>,<country>Spain</country>,</nlm:aff></affiliation></author><author><name sortKey="Rodriguez, Primitiva Menendez" sort="Rodriguez, Primitiva Menendez" uniqKey="Rodriguez P" first="Primitiva Menéndez" last="Rodríguez">Primitiva Menéndez Rodríguez</name><affiliation><nlm:aff id="af24"><addr-line>Servicio de Anatomía Patológica</addr-line>,<institution>Hospital Monte Naranco</institution>,<addr-line>Oviedo</addr-line>,<country>Spain</country>,</nlm:aff></affiliation></author><author><name sortKey="Benitez, Javier" sort="Benitez, Javier" uniqKey="Benitez J" first="Javier" last="Benítez">Javier Benítez</name><affiliation><nlm:aff id="af22"><addr-line>Human Cancer Genetic Group</addr-line>,<institution>Spanish National Cancer Research Centre (CNIO)</institution>,<addr-line>Madrid</addr-line>,<country>Spain</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af26"><institution>CIBERER</institution>,<addr-line>Madrid</addr-line>,<country>Spain</country>,</nlm:aff></affiliation></author><author><name sortKey="Brauch, Hiltrud" sort="Brauch, Hiltrud" uniqKey="Brauch H" first="Hiltrud" last="Brauch">Hiltrud Brauch</name><affiliation><nlm:aff id="af27"><institution>Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology</institution>,<addr-line>Stuttgart</addr-line>,<country>Germany</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af28"><institution>University Tübingen</institution>,<addr-line>Tübingen</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Justenhoven, Christina" sort="Justenhoven, Christina" uniqKey="Justenhoven C" first="Christina" last="Justenhoven">Christina Justenhoven</name><affiliation><nlm:aff id="af27"><institution>Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology</institution>,<addr-line>Stuttgart</addr-line>,<country>Germany</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af28"><institution>University Tübingen</institution>,<addr-line>Tübingen</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Ko, Yon Dschun" sort="Ko, Yon Dschun" uniqKey="Ko Y" first="Yon-Dschun" last="Ko">Yon-Dschun Ko</name><affiliation><nlm:aff id="af29"><addr-line>Department of Internal Medicine</addr-line>,<institution>Evangelische Kliniken Bonn gGmbH</institution>,<addr-line>Johanniter Krankenhaus, Bonn</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Hamann, Ute" sort="Hamann, Ute" uniqKey="Hamann U" first="Ute" last="Hamann">Ute Hamann</name><affiliation><nlm:aff id="af32"><addr-line>Molecular Genetics of Breast Cancer</addr-line>,<institution>Deutsches Krebsforschungszentrum (DKFZ)</institution>,<addr-line>Heidelberg</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Fischer, Hans Peter" sort="Fischer, Hans Peter" uniqKey="Fischer H" first="Hans-Peter" last="Fischer">Hans-Peter Fischer</name><affiliation><nlm:aff id="af33"><institution>Institute of Pathology, Medical Faculty of the University of Bonn</institution>,<addr-line>Bonn</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Bruning, Thomas" sort="Bruning, Thomas" uniqKey="Bruning T" first="Thomas" last="Brüning">Thomas Brüning</name><affiliation><nlm:aff id="af34"><institution>Institute of Prevention and Occupational Medicine of the German Social Accident Insurance (IPA)</institution>,<addr-line>Bochum</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Pesch, Beate" sort="Pesch, Beate" uniqKey="Pesch B" first="Beate" last="Pesch">Beate Pesch</name><affiliation><nlm:aff id="af34"><institution>Institute of Prevention and Occupational Medicine of the German Social Accident Insurance (IPA)</institution>,<addr-line>Bochum</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Chang Claude, Jenny" sort="Chang Claude, Jenny" uniqKey="Chang Claude J" first="Jenny" last="Chang-Claude">Jenny Chang-Claude</name><affiliation><nlm:aff id="af18"><addr-line>Division of Cancer Epidemiology</addr-line>,<institution>German Cancer Research Center</institution>,<addr-line>Heidelberg</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Wang Gohrke, Shan" sort="Wang Gohrke, Shan" uniqKey="Wang Gohrke S" first="Shan" last="Wang-Gohrke">Shan Wang-Gohrke</name><affiliation><nlm:aff id="af35"><addr-line>Department of Obstetrics and Gynecology</addr-line>,<institution>University of Ulm</institution>,<addr-line>Ulm</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Bremer, Michael" sort="Bremer, Michael" uniqKey="Bremer M" first="Michael" last="Bremer">Michael Bremer</name><affiliation><nlm:aff id="af36"><addr-line>Hannover Medical School</addr-line>,<institution>Clinics of Radiation Oncology</institution>,<addr-line>Hannover</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Karstens, Johann H" sort="Karstens, Johann H" uniqKey="Karstens J" first="Johann H." last="Karstens">Johann H. Karstens</name><affiliation><nlm:aff id="af36"><addr-line>Hannover Medical School</addr-line>,<institution>Clinics of Radiation Oncology</institution>,<addr-line>Hannover</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Hillemanns, Peter" sort="Hillemanns, Peter" uniqKey="Hillemanns P" first="Peter" last="Hillemanns">Peter Hillemanns</name><affiliation><nlm:aff id="af37"><institution>Clinics of Obstetrics and Gynaecology</institution>,<addr-line>Hannover</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Dork, Thilo" sort="Dork, Thilo" uniqKey="Dork T" first="Thilo" last="Dörk">Thilo Dörk</name><affiliation><nlm:aff id="af37"><institution>Clinics of Obstetrics and Gynaecology</institution>,<addr-line>Hannover</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Nevanlinna, Heli A" sort="Nevanlinna, Heli A" uniqKey="Nevanlinna H" first="Heli A." last="Nevanlinna">Heli A. Nevanlinna</name><affiliation><nlm:aff id="af38"><addr-line>Department of Obstetrics and Gynecology</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Heikkinen, Tuomas" sort="Heikkinen, Tuomas" uniqKey="Heikkinen T" first="Tuomas" last="Heikkinen">Tuomas Heikkinen</name><affiliation><nlm:aff id="af38"><addr-line>Department of Obstetrics and Gynecology</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Heikkil, P Ivi" sort="Heikkil, P Ivi" uniqKey="Heikkil P" first="P Ivi" last="Heikkil">P Ivi Heikkil</name><affiliation><nlm:aff wicri:cut=" and" id="af40"><addr-line>Department of Pathology</addr-line></nlm:aff></affiliation></author><author><name sortKey="Blomqvist, Carl" sort="Blomqvist, Carl" uniqKey="Blomqvist C" first="Carl" last="Blomqvist">Carl Blomqvist</name><affiliation><nlm:aff id="af41"><addr-line>Department of Oncology</addr-line>,<institution>Helsinki University Central Hospital</institution>,<addr-line>Helsinki</addr-line>,<country>Finland</country>,</nlm:aff></affiliation></author><author><name sortKey="Aittom Ki, Kristiina" sort="Aittom Ki, Kristiina" uniqKey="Aittom Ki K" first="Kristiina" last="Aittom Ki">Kristiina Aittom Ki</name><affiliation><nlm:aff id="af39"><addr-line>Department of Clinical Genetics</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Aaltonen, Kirsimari" sort="Aaltonen, Kirsimari" uniqKey="Aaltonen K" first="Kirsimari" last="Aaltonen">Kirsimari Aaltonen</name><affiliation><nlm:aff id="af38"><addr-line>Department of Obstetrics and Gynecology</addr-line>,</nlm:aff></affiliation><affiliation><nlm:aff id="af41"><addr-line>Department of Oncology</addr-line>,<institution>Helsinki University Central Hospital</institution>,<addr-line>Helsinki</addr-line>,<country>Finland</country>,</nlm:aff></affiliation></author><author><name sortKey="Lindblom, Annika" sort="Lindblom, Annika" uniqKey="Lindblom A" first="Annika" last="Lindblom">Annika Lindblom</name><affiliation><nlm:aff id="af42"><addr-line>Department of Molecular Medicine and Surgery,</addr-line></nlm:aff></affiliation></author><author><name sortKey="Margolin, Sara" sort="Margolin, Sara" uniqKey="Margolin S" first="Sara" last="Margolin">Sara Margolin</name><affiliation><nlm:aff wicri:cut=" and" id="af43"><addr-line>Department of Oncology and Pathology</addr-line></nlm:aff></affiliation></author><author><name sortKey="Mannermaa, Arto" sort="Mannermaa, Arto" uniqKey="Mannermaa A" first="Arto" last="Mannermaa">Arto Mannermaa</name><affiliation><nlm:aff id="af45"><addr-line>Department of Pathology</addr-line>,<institution>Institute of Clinical Medicine, University of Eastern Finland and Kuopio University Hospital</institution>, Kuopio,<country>Finland</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af46"><institution>Biocenter Kuopio</institution>,<addr-line>Kuopio</addr-line>,<country>Finland</country>,</nlm:aff></affiliation></author><author><name sortKey="Kosma, Veli Matti" sort="Kosma, Veli Matti" uniqKey="Kosma V" first="Veli-Matti" last="Kosma">Veli-Matti Kosma</name><affiliation><nlm:aff id="af45"><addr-line>Department of Pathology</addr-line>,<institution>Institute of Clinical Medicine, University of Eastern Finland and Kuopio University Hospital</institution>, Kuopio,<country>Finland</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af46"><institution>Biocenter Kuopio</institution>,<addr-line>Kuopio</addr-line>,<country>Finland</country>,</nlm:aff></affiliation></author><author><name sortKey="Kauppinen, Jaana M" sort="Kauppinen, Jaana M" uniqKey="Kauppinen J" first="Jaana M." last="Kauppinen">Jaana M. Kauppinen</name><affiliation><nlm:aff id="af45"><addr-line>Department of Pathology</addr-line>,<institution>Institute of Clinical Medicine, University of Eastern Finland and Kuopio University Hospital</institution>, Kuopio,<country>Finland</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af46"><institution>Biocenter Kuopio</institution>,<addr-line>Kuopio</addr-line>,<country>Finland</country>,</nlm:aff></affiliation></author><author><name sortKey="Kataja, Vesa" sort="Kataja, Vesa" uniqKey="Kataja V" first="Vesa" last="Kataja">Vesa Kataja</name><affiliation><nlm:aff id="af47"><addr-line>Department of Oncology</addr-line>,<institution>Vaasa Central Hospital</institution>,<addr-line>Vaasa</addr-line>,<country>Finland</country>,</nlm:aff></affiliation></author><author><name sortKey="Auvinen, P Ivi" sort="Auvinen, P Ivi" uniqKey="Auvinen P" first="P Ivi" last="Auvinen">P Ivi Auvinen</name><affiliation><nlm:aff wicri:cut=" and" id="af48"><addr-line>Department of Oncology</addr-line></nlm:aff></affiliation></author><author><name sortKey="Eskelinen, Matti" sort="Eskelinen, Matti" uniqKey="Eskelinen M" first="Matti" last="Eskelinen">Matti Eskelinen</name><affiliation><nlm:aff id="af49"><addr-line>Department of Surgery</addr-line>,<institution>Kuopio University Hospital</institution>,<addr-line>Kuopio</addr-line>,<country>Finland</country>,</nlm:aff></affiliation></author><author><name sortKey="Soini, Ylermi" sort="Soini, Ylermi" uniqKey="Soini Y" first="Ylermi" last="Soini">Ylermi Soini</name><affiliation><nlm:aff id="af45"><addr-line>Department of Pathology</addr-line>,<institution>Institute of Clinical Medicine, University of Eastern Finland and Kuopio University Hospital</institution>, Kuopio,<country>Finland</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af46"><institution>Biocenter Kuopio</institution>,<addr-line>Kuopio</addr-line>,<country>Finland</country>,</nlm:aff></affiliation></author><author><name sortKey="Chenevix Trench, Georgia" sort="Chenevix Trench, Georgia" uniqKey="Chenevix Trench G" first="Georgia" last="Chenevix-Trench">Georgia Chenevix-Trench</name><affiliation><nlm:aff id="af50"><institution>Queensland Institute of Medical Research</institution>,<addr-line>Brisbane</addr-line>,<country>Australia</country>,</nlm:aff></affiliation></author><author><name sortKey="Spurdle, Amanda B" sort="Spurdle, Amanda B" uniqKey="Spurdle A" first="Amanda B." last="Spurdle">Amanda B. Spurdle</name><affiliation><nlm:aff id="af50"><institution>Queensland Institute of Medical Research</institution>,<addr-line>Brisbane</addr-line>,<country>Australia</country>,</nlm:aff></affiliation></author><author><name sortKey="Beesley, Jonathan" sort="Beesley, Jonathan" uniqKey="Beesley J" first="Jonathan" last="Beesley">Jonathan Beesley</name><affiliation><nlm:aff id="af50"><institution>Queensland Institute of Medical Research</institution>,<addr-line>Brisbane</addr-line>,<country>Australia</country>,</nlm:aff></affiliation></author><author><name sortKey="Chen, Xiaoqing" sort="Chen, Xiaoqing" uniqKey="Chen X" first="Xiaoqing" last="Chen">Xiaoqing Chen</name><affiliation><nlm:aff id="af50"><institution>Queensland Institute of Medical Research</institution>,<addr-line>Brisbane</addr-line>,<country>Australia</country>,</nlm:aff></affiliation></author><author><name sortKey="Holland, Helene" sort="Holland, Helene" uniqKey="Holland H" first="Helene" last="Holland">Helene Holland</name><affiliation><nlm:aff id="af50"><institution>Queensland Institute of Medical Research</institution>,<addr-line>Brisbane</addr-line>,<country>Australia</country>,</nlm:aff></affiliation></author><author><name sortKey="Lambrechts, Diether" sort="Lambrechts, Diether" uniqKey="Lambrechts D" first="Diether" last="Lambrechts">Diether Lambrechts</name><affiliation><nlm:aff id="af52"><institution>Vesalius Research Center</institution>,<addr-line>KU Leuven and VIB, Leuven</addr-line>,<country>Belgium</country>,</nlm:aff></affiliation></author><author><name sortKey="Claes, Bart" sort="Claes, Bart" uniqKey="Claes B" first="Bart" last="Claes">Bart Claes</name><affiliation><nlm:aff id="af52"><institution>Vesalius Research Center</institution>,<addr-line>KU Leuven and VIB, Leuven</addr-line>,<country>Belgium</country>,</nlm:aff></affiliation></author><author><name sortKey="Vandorpe, Thijs" sort="Vandorpe, Thijs" uniqKey="Vandorpe T" first="Thijs" last="Vandorpe">Thijs Vandorpe</name><affiliation><nlm:aff id="af53"><addr-line>Multidisciplinary Breast Center</addr-line>,<institution>University Hospitals Leuven</institution>,<country>Belgium</country>,</nlm:aff></affiliation></author><author><name sortKey="Neven, Patrick" sort="Neven, Patrick" uniqKey="Neven P" first="Patrick" last="Neven">Patrick Neven</name><affiliation><nlm:aff id="af53"><addr-line>Multidisciplinary Breast Center</addr-line>,<institution>University Hospitals Leuven</institution>,<country>Belgium</country>,</nlm:aff></affiliation></author><author><name sortKey="Wildiers, Hans" sort="Wildiers, Hans" uniqKey="Wildiers H" first="Hans" last="Wildiers">Hans Wildiers</name><affiliation><nlm:aff id="af53"><addr-line>Multidisciplinary Breast Center</addr-line>,<institution>University Hospitals Leuven</institution>,<country>Belgium</country>,</nlm:aff></affiliation></author><author><name sortKey="Flesch Janys, Dieter" sort="Flesch Janys, Dieter" uniqKey="Flesch Janys D" first="Dieter" last="Flesch-Janys">Dieter Flesch-Janys</name><affiliation><nlm:aff id="af54"><addr-line>Institute for Medical Biometrics and Epidemiology</addr-line>,<institution>University Clinic Hamburg-Eppendorf</institution>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Hein, Rebecca" sort="Hein, Rebecca" uniqKey="Hein R" first="Rebecca" last="Hein">Rebecca Hein</name><affiliation><nlm:aff id="af18"><addr-line>Division of Cancer Epidemiology</addr-line>,<institution>German Cancer Research Center</institution>,<addr-line>Heidelberg</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Loning, Thomas" sort="Loning, Thomas" uniqKey="Loning T" first="Thomas" last="Löning">Thomas Löning</name><affiliation><nlm:aff id="af55"><addr-line>Albertinen Pathology Department, Hamburg</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Kosel, Matthew" sort="Kosel, Matthew" uniqKey="Kosel M" first="Matthew" last="Kosel">Matthew Kosel</name><affiliation><nlm:aff wicri:cut=" and" id="af5"><addr-line>Department of Laboratory Medicine and Pathology</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af6"><addr-line>Department of Health Sciences Research</addr-line>,<institution>Mayo Clinic</institution>,<addr-line>Rochester, MN</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Fredericksen, Zachary S" sort="Fredericksen, Zachary S" uniqKey="Fredericksen Z" first="Zachary S." last="Fredericksen">Zachary S. Fredericksen</name><affiliation><nlm:aff wicri:cut=" and" id="af5"><addr-line>Department of Laboratory Medicine and Pathology</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af6"><addr-line>Department of Health Sciences Research</addr-line>,<institution>Mayo Clinic</institution>,<addr-line>Rochester, MN</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Wang, Xianshu" sort="Wang, Xianshu" uniqKey="Wang X" first="Xianshu" last="Wang">Xianshu Wang</name><affiliation><nlm:aff wicri:cut=" and" id="af5"><addr-line>Department of Laboratory Medicine and Pathology</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af6"><addr-line>Department of Health Sciences Research</addr-line>,<institution>Mayo Clinic</institution>,<addr-line>Rochester, MN</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Giles, Graham G" sort="Giles, Graham G" uniqKey="Giles G" first="Graham G." last="Giles">Graham G. Giles</name><affiliation><nlm:aff id="af57"><addr-line>Cancer Epidemiology Centre</addr-line>,<institution>The Cancer Council Victoria</institution>,<addr-line>Melbourne</addr-line>,<country>Australia</country>,</nlm:aff></affiliation></author><author><name sortKey="Baglietto, Laura" sort="Baglietto, Laura" uniqKey="Baglietto L" first="Laura" last="Baglietto">Laura Baglietto</name><affiliation><nlm:aff id="af58"><addr-line>Department of Anatomical Pathology</addr-line>,<institution>Alfred Hospital</institution>,<addr-line>Melbourne</addr-line>,<country>Australia</country>,</nlm:aff></affiliation></author><author><name sortKey="Severi, Gianluca" sort="Severi, Gianluca" uniqKey="Severi G" first="Gianluca" last="Severi">Gianluca Severi</name><affiliation><nlm:aff id="af57"><addr-line>Cancer Epidemiology Centre</addr-line>,<institution>The Cancer Council Victoria</institution>,<addr-line>Melbourne</addr-line>,<country>Australia</country>,</nlm:aff></affiliation></author><author><name sortKey="Mclean, Catriona" sort="Mclean, Catriona" uniqKey="Mclean C" first="Catriona" last="Mclean">Catriona Mclean</name><affiliation><nlm:aff id="af58"><addr-line>Department of Anatomical Pathology</addr-line>,<institution>Alfred Hospital</institution>,<addr-line>Melbourne</addr-line>,<country>Australia</country>,</nlm:aff></affiliation></author><author><name sortKey="Haiman, Christopher A" sort="Haiman, Christopher A" uniqKey="Haiman C" first="Christopher A." last="Haiman">Christopher A. Haiman</name><affiliation><nlm:aff id="af59"><addr-line>Department of Preventive Medicine, Keck School of Medicine and Norris Comprehensive Cancer Center</addr-line>,<institution>University of Southern California</institution>,<addr-line>Los Angeles, CA 90089</addr-line>, USA,</nlm:aff></affiliation></author><author><name sortKey="Henderson, Brian E" sort="Henderson, Brian E" uniqKey="Henderson B" first="Brian E." last="Henderson">Brian E. Henderson</name><affiliation><nlm:aff id="af59"><addr-line>Department of Preventive Medicine, Keck School of Medicine and Norris Comprehensive Cancer Center</addr-line>,<institution>University of Southern California</institution>,<addr-line>Los Angeles, CA 90089</addr-line>, USA,</nlm:aff></affiliation></author><author><name sortKey="Le Marchand, Loic" sort="Le Marchand, Loic" uniqKey="Le Marchand L" first="Loic" last="Le Marchand">Loic Le Marchand</name><affiliation><nlm:aff id="af60"><addr-line>Epidemiology Program</addr-line>,<institution>Cancer Research Center, University of Hawaii</institution>,<addr-line>Honolulu, HI 96813</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Kolonel, Laurence N" sort="Kolonel, Laurence N" uniqKey="Kolonel L" first="Laurence N." last="Kolonel">Laurence N. Kolonel</name><affiliation><nlm:aff id="af60"><addr-line>Epidemiology Program</addr-line>,<institution>Cancer Research Center, University of Hawaii</institution>,<addr-line>Honolulu, HI 96813</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Grenaker Aln S, Grethe" sort="Grenaker Aln S, Grethe" uniqKey="Grenaker Aln S G" first="Grethe" last="Grenaker Aln S">Grethe Grenaker Aln S</name><affiliation><nlm:aff id="af61"><addr-line>Department of Genetics</addr-line>,<institution>Institute for Cancer Research, Oslo University Hospital</institution>,<addr-line>Radiumhospitalet, Montebello 0310, Oslo</addr-line>,<country>Norway</country>,</nlm:aff></affiliation></author><author><name sortKey="Kristensen, Vessela" sort="Kristensen, Vessela" uniqKey="Kristensen V" first="Vessela" last="Kristensen">Vessela Kristensen</name><affiliation><nlm:aff id="af61"><addr-line>Department of Genetics</addr-line>,<institution>Institute for Cancer Research, Oslo University Hospital</institution>,<addr-line>Radiumhospitalet, Montebello 0310, Oslo</addr-line>,<country>Norway</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af62"><addr-line>Faculty of Medicine</addr-line><institution>(Faculty Division Ahus)</institution>,<addr-line>UiO</addr-line>,<country>Norway</country>,</nlm:aff></affiliation></author><author><name sortKey="B Rresen Dale, Anne Lise" sort="B Rresen Dale, Anne Lise" uniqKey="B Rresen Dale A" first="Anne-Lise" last="B Rresen-Dale">Anne-Lise B Rresen-Dale</name><affiliation><nlm:aff id="af61"><addr-line>Department of Genetics</addr-line>,<institution>Institute for Cancer Research, Oslo University Hospital</institution>,<addr-line>Radiumhospitalet, Montebello 0310, Oslo</addr-line>,<country>Norway</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af62"><addr-line>Faculty of Medicine</addr-line><institution>(Faculty Division Ahus)</institution>,<addr-line>UiO</addr-line>,<country>Norway</country>,</nlm:aff></affiliation></author><author><name sortKey="Hunter, David J" sort="Hunter, David J" uniqKey="Hunter D" first="David J." last="Hunter">David J. Hunter</name><affiliation><nlm:aff id="af63"><addr-line>Channing Laboratory, Department of Medicine</addr-line>,<institution>Brigham and Womens Hospital and Harvard Medical school</institution>, Boston, MA, USA,</nlm:aff></affiliation><affiliation><nlm:aff id="af64"><addr-line>Department of Epidemiology</addr-line>,<institution>Harvard school of public health</institution>,<addr-line>Boston, MA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Hankinson, Susan E" sort="Hankinson, Susan E" uniqKey="Hankinson S" first="Susan E." last="Hankinson">Susan E. Hankinson</name><affiliation><nlm:aff id="af63"><addr-line>Channing Laboratory, Department of Medicine</addr-line>,<institution>Brigham and Womens Hospital and Harvard Medical school</institution>, Boston, MA, USA,</nlm:aff></affiliation><affiliation><nlm:aff id="af64"><addr-line>Department of Epidemiology</addr-line>,<institution>Harvard school of public health</institution>,<addr-line>Boston, MA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L." last="Andrulis">Irene L. Andrulis</name><affiliation><nlm:aff id="af65"><institution>Samuel Lunenfeld Research Institute, Mount Sinai Hospital</institution>,<addr-line>Ontario Cancer Genetics Network, Cancer Care Ontario, Ontario</addr-line>,<country>Canada</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af66"><addr-line>Department of Molecular Genetics and</addr-line></nlm:aff></affiliation><affiliation><nlm:aff wicri:cut=" and" id="af67"><addr-line>Laboratory Medicine</addr-line><addr-line>Pathobiology</addr-line>,<institution>University of Toronto</institution>,<addr-line>Toronto, Ontario</addr-line>,<country>Canada</country>,</nlm:aff></affiliation></author><author><name sortKey="Marie Mulligan, Anna" sort="Marie Mulligan, Anna" uniqKey="Marie Mulligan A" first="Anna" last="Marie Mulligan">Anna Marie Mulligan</name><affiliation><nlm:aff wicri:cut=" and" id="af67"><addr-line>Laboratory Medicine</addr-line><addr-line>Pathobiology</addr-line>,<institution>University of Toronto</institution>,<addr-line>Toronto, Ontario</addr-line>,<country>Canada</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af68"><addr-line>Keenan Research Centre</addr-line>,<institution>Li Ka Shing Knowledge Institute of St Michael's Hospital</institution>,<addr-line>Toronto, Ontario</addr-line>,<country>Canada</country>,</nlm:aff></affiliation></author><author><name sortKey="O Malley, Frances P" sort="O Malley, Frances P" uniqKey="O Malley F" first="Frances P." last="O'Malley">Frances P. O'Malley</name><affiliation><nlm:aff wicri:cut=" and" id="af67"><addr-line>Laboratory Medicine</addr-line><addr-line>Pathobiology</addr-line>,<institution>University of Toronto</institution>,<addr-line>Toronto, Ontario</addr-line>,<country>Canada</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af69"><addr-line>The Department of Laboratory Medicine and the</addr-line><institution>Keenan Research Centre of the Li Ka Shing Knowledge Institute, St Michael's Hospital,</institution><addr-line>Toronto, Ontario</addr-line>,<country>Canada</country></nlm:aff></affiliation></author><author><name sortKey="Devilee, Peter" sort="Devilee, Peter" uniqKey="Devilee P" first="Peter" last="Devilee">Peter Devilee</name><affiliation><nlm:aff id="af70"><addr-line>Department Human Genetics & Department of Pathology</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Huijts, Petra E A" sort="Huijts, Petra E A" uniqKey="Huijts P" first="Petra E. A." last="Huijts">Petra E. A. Huijts</name><affiliation><nlm:aff wicri:cut=" and" id="af71"><addr-line>Clinical Genetics</addr-line></nlm:aff></affiliation></author><author><name sortKey="Tollenaar, Rob A E M" sort="Tollenaar, Rob A E M" uniqKey="Tollenaar R" first="Rob A. E. M." last="Tollenaar">Rob A. E. M. Tollenaar</name><affiliation><nlm:aff id="af72"><addr-line>Surgical Oncology</addr-line>,<institution>Leiden University Medical Center</institution>,<addr-line>Leiden</addr-line>,<country>The Netherlands</country>,</nlm:aff></affiliation></author><author><name sortKey="Van Asperen, Christi J" sort="Van Asperen, Christi J" uniqKey="Van Asperen C" first="Christi J." last="Van Asperen">Christi J. Van Asperen</name><affiliation><nlm:aff wicri:cut=" and" id="af71"><addr-line>Clinical Genetics</addr-line></nlm:aff></affiliation></author><author><name sortKey="Seynaeve, Caroline S" sort="Seynaeve, Caroline S" uniqKey="Seynaeve C" first="Caroline S." last="Seynaeve">Caroline S. Seynaeve</name><affiliation><nlm:aff id="af73"><addr-line>Department of Medical Oncology</addr-line>,<institution>Rotterdam Family Cancer Clinic, Erasmus MC-Daniel den Hoed Cancer Center</institution>,<addr-line>Rotterdam</addr-line>,<country>The Netherlands</country>,</nlm:aff></affiliation></author><author><name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J." last="Chanock">Stephen J. Chanock</name><affiliation><nlm:aff id="af74"><addr-line>Advanced Technology Center</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Gaithersburg, MD 20892-4605</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Lissowska, Jolanta" sort="Lissowska, Jolanta" uniqKey="Lissowska J" first="Jolanta" last="Lissowska">Jolanta Lissowska</name><affiliation><nlm:aff id="af75"><addr-line>Department of Cancer Epidemiology and Prevention</addr-line>,<institution>Cancer Center and M. Sklodowska-Curie Institute of Oncology</institution>,<addr-line>02-781 Warsaw</addr-line>,<country>Poland</country>,</nlm:aff></affiliation></author><author><name sortKey="Brinton, Louise" sort="Brinton, Louise" uniqKey="Brinton L" first="Louise" last="Brinton">Louise Brinton</name><affiliation><nlm:aff id="af76"><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Rockville, MD 20852-7234</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Peplonska, Beata" sort="Peplonska, Beata" uniqKey="Peplonska B" first="Beata" last="Peplonska">Beata Peplonska</name><affiliation><nlm:aff id="af77"><institution>Nofer Institute of Occupational Medicine</institution>,<addr-line>91-348 Lodz</addr-line>,<country>Poland</country>,</nlm:aff></affiliation></author><author><name sortKey="Figueroa, Jonine" sort="Figueroa, Jonine" uniqKey="Figueroa J" first="Jonine" last="Figueroa">Jonine Figueroa</name><affiliation><nlm:aff id="af4"><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Rockville, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Yang, Xiaohong R" sort="Yang, Xiaohong R" uniqKey="Yang X" first="Xiaohong R." last="Yang">Xiaohong R. Yang</name><affiliation><nlm:aff id="af4"><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Rockville, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Hooning, Maartje J" sort="Hooning, Maartje J" uniqKey="Hooning M" first="Maartje J." last="Hooning">Maartje J. Hooning</name><affiliation><nlm:aff id="af78"><addr-line>Department of Medical Oncology</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Hollestelle, Antoinette" sort="Hollestelle, Antoinette" uniqKey="Hollestelle A" first="Antoinette" last="Hollestelle">Antoinette Hollestelle</name><affiliation><nlm:aff id="af78"><addr-line>Department of Medical Oncology</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Oldenburg, Rogier A" sort="Oldenburg, Rogier A" uniqKey="Oldenburg R" first="Rogier A." last="Oldenburg">Rogier A. Oldenburg</name><affiliation><nlm:aff wicri:cut=" and" id="af79"><addr-line>Department of Clinical Genetics</addr-line></nlm:aff></affiliation></author><author><name sortKey="Jager, Agnes" sort="Jager, Agnes" uniqKey="Jager A" first="Agnes" last="Jager">Agnes Jager</name><affiliation><nlm:aff id="af78"><addr-line>Department of Medical Oncology</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Kriege, Mieke" sort="Kriege, Mieke" uniqKey="Kriege M" first="Mieke" last="Kriege">Mieke Kriege</name><affiliation><nlm:aff id="af78"><addr-line>Department of Medical Oncology</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Ozturk, Bahar" sort="Ozturk, Bahar" uniqKey="Ozturk B" first="Bahar" last="Ozturk">Bahar Ozturk</name><affiliation><nlm:aff id="af78"><addr-line>Department of Medical Oncology</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Van Leenders, Geert J L H" sort="Van Leenders, Geert J L H" uniqKey="Van Leenders G" first="Geert J. L. H." last="Van Leenders">Geert J. L. H. Van Leenders</name><affiliation><nlm:aff id="af80"><addr-line>Department of Pathology</addr-line>,<institution>Rotterdam Family Cancer Clinic, Erasmus University Medical Center</institution>,<addr-line>Rotterdam</addr-line>,<country>the Netherlands</country>,</nlm:aff></affiliation></author><author><name sortKey="Hall, Per" sort="Hall, Per" uniqKey="Hall P" first="Per" last="Hall">Per Hall</name><affiliation><nlm:aff id="af44"><addr-line>Department of Medical Epidemiology and Biostatistics</addr-line>,<institution>Karolinska Institute</institution>,<addr-line>Stockholm</addr-line>,<country>Sweden</country>,</nlm:aff></affiliation></author><author><name sortKey="Czene, Kamila" sort="Czene, Kamila" uniqKey="Czene K" first="Kamila" last="Czene">Kamila Czene</name><affiliation><nlm:aff id="af44"><addr-line>Department of Medical Epidemiology and Biostatistics</addr-line>,<institution>Karolinska Institute</institution>,<addr-line>Stockholm</addr-line>,<country>Sweden</country>,</nlm:aff></affiliation></author><author><name sortKey="Humphreys, Keith" sort="Humphreys, Keith" uniqKey="Humphreys K" first="Keith" last="Humphreys">Keith Humphreys</name><affiliation><nlm:aff id="af44"><addr-line>Department of Medical Epidemiology and Biostatistics</addr-line>,<institution>Karolinska Institute</institution>,<addr-line>Stockholm</addr-line>,<country>Sweden</country>,</nlm:aff></affiliation></author><author><name sortKey="Liu, Jianjun" sort="Liu, Jianjun" uniqKey="Liu J" first="Jianjun" last="Liu">Jianjun Liu</name><affiliation><nlm:aff id="af81"><addr-line>Human Genetics Laboratory</addr-line>,<institution>Genome Institute of Singapore</institution>,<country>Singapore</country>,</nlm:aff></affiliation></author><author><name sortKey="Cox, Angela" sort="Cox, Angela" uniqKey="Cox A" first="Angela" last="Cox">Angela Cox</name><affiliation><nlm:aff id="af82"><addr-line>Department of Oncology, Institute for Cancer Studies</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Connley, Daniel" sort="Connley, Daniel" uniqKey="Connley D" first="Daniel" last="Connley">Daniel Connley</name><affiliation><nlm:aff id="af82"><addr-line>Department of Oncology, Institute for Cancer Studies</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Cramp, Helen E" sort="Cramp, Helen E" uniqKey="Cramp H" first="Helen E." last="Cramp">Helen E. Cramp</name><affiliation><nlm:aff id="af82"><addr-line>Department of Oncology, Institute for Cancer Studies</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Cross, Simon S" sort="Cross, Simon S" uniqKey="Cross S" first="Simon S." last="Cross">Simon S. Cross</name><affiliation><nlm:aff wicri:cut=" and" id="af83"><addr-line>Academic Unit of Pathology, Department of Oncology</addr-line></nlm:aff></affiliation></author><author><name sortKey="Balasubramanian, Sabapathy P" sort="Balasubramanian, Sabapathy P" uniqKey="Balasubramanian S" first="Sabapathy P." last="Balasubramanian">Sabapathy P. Balasubramanian</name><affiliation><nlm:aff id="af84"><addr-line>Academic Unit of Surgical Oncology, Department of Oncology</addr-line>,<institution>University of Sheffield Medical School</institution>,<addr-line>Sheffield</addr-line>,<country>UK</country>,</nlm:aff></affiliation></author><author><name sortKey="Reed, Malcolm W R" sort="Reed, Malcolm W R" uniqKey="Reed M" first="Malcolm W. R." last="Reed">Malcolm W. R. Reed</name><affiliation><nlm:aff id="af84"><addr-line>Academic Unit of Surgical Oncology, Department of Oncology</addr-line>,<institution>University of Sheffield Medical School</institution>,<addr-line>Sheffield</addr-line>,<country>UK</country>,</nlm:aff></affiliation></author><author><name sortKey="Dunning, Alison M" sort="Dunning, Alison M" uniqKey="Dunning A" first="Alison M." last="Dunning">Alison M. Dunning</name><affiliation><nlm:aff wicri:cut=" and" id="af85"><addr-line>Department of Oncology</addr-line></nlm:aff></affiliation></author><author><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F." last="Easton">Douglas F. Easton</name><affiliation><nlm:aff id="af86"><addr-line>Department of Public Health and Primary Care</addr-line>,<institution>University of Cambridge</institution>,<addr-line>Cambridge</addr-line>,<country>UK</country>,</nlm:aff></affiliation></author><author><name sortKey="Humphreys, Manjeet K" sort="Humphreys, Manjeet K" uniqKey="Humphreys M" first="Manjeet K." last="Humphreys">Manjeet K. Humphreys</name><affiliation><nlm:aff id="af86"><addr-line>Department of Public Health and Primary Care</addr-line>,<institution>University of Cambridge</institution>,<addr-line>Cambridge</addr-line>,<country>UK</country>,</nlm:aff></affiliation></author><author><name sortKey="Caldas, Carlos" sort="Caldas, Carlos" uniqKey="Caldas C" first="Carlos" last="Caldas">Carlos Caldas</name><affiliation><nlm:aff wicri:cut=" and" id="af85"><addr-line>Department of Oncology</addr-line></nlm:aff></affiliation></author><author><name sortKey="Blows, Fiona" sort="Blows, Fiona" uniqKey="Blows F" first="Fiona" last="Blows">Fiona Blows</name><affiliation><nlm:aff wicri:cut=" and" id="af85"><addr-line>Department of Oncology</addr-line></nlm:aff></affiliation></author><author><name sortKey="Driver, Kristy" sort="Driver, Kristy" uniqKey="Driver K" first="Kristy" last="Driver">Kristy Driver</name><affiliation><nlm:aff wicri:cut=" and" id="af85"><addr-line>Department of Oncology</addr-line></nlm:aff></affiliation></author><author><name sortKey="Provenzano, Elena" sort="Provenzano, Elena" uniqKey="Provenzano E" first="Elena" last="Provenzano">Elena Provenzano</name><affiliation><nlm:aff wicri:cut=" and" id="af85"><addr-line>Department of Oncology</addr-line></nlm:aff></affiliation></author><author><name sortKey="Lubinski, Jan" sort="Lubinski, Jan" uniqKey="Lubinski J" first="Jan" last="Lubinski">Jan Lubinski</name><affiliation><nlm:aff id="af87"><addr-line>Department of Genetics and Pathology</addr-line>,<institution>International Hereditary Cancer Center, Pomeranian Medical University</institution>,<addr-line>Szczecin</addr-line>,<country>Poland</country>,</nlm:aff></affiliation></author><author><name sortKey="Jakubowska, Anna" sort="Jakubowska, Anna" uniqKey="Jakubowska A" first="Anna" last="Jakubowska">Anna Jakubowska</name><affiliation><nlm:aff id="af87"><addr-line>Department of Genetics and Pathology</addr-line>,<institution>International Hereditary Cancer Center, Pomeranian Medical University</institution>,<addr-line>Szczecin</addr-line>,<country>Poland</country>,</nlm:aff></affiliation></author><author><name sortKey="Huzarski, Tomasz" sort="Huzarski, Tomasz" uniqKey="Huzarski T" first="Tomasz" last="Huzarski">Tomasz Huzarski</name><affiliation><nlm:aff id="af87"><addr-line>Department of Genetics and Pathology</addr-line>,<institution>International Hereditary Cancer Center, Pomeranian Medical University</institution>,<addr-line>Szczecin</addr-line>,<country>Poland</country>,</nlm:aff></affiliation></author><author><name sortKey="Byrski, Tomasz" sort="Byrski, Tomasz" uniqKey="Byrski T" first="Tomasz" last="Byrski">Tomasz Byrski</name><affiliation><nlm:aff id="af87"><addr-line>Department of Genetics and Pathology</addr-line>,<institution>International Hereditary Cancer Center, Pomeranian Medical University</institution>,<addr-line>Szczecin</addr-line>,<country>Poland</country>,</nlm:aff></affiliation></author><author><name sortKey="Cybulski, Cezary" sort="Cybulski, Cezary" uniqKey="Cybulski C" first="Cezary" last="Cybulski">Cezary Cybulski</name><affiliation><nlm:aff id="af87"><addr-line>Department of Genetics and Pathology</addr-line>,<institution>International Hereditary Cancer Center, Pomeranian Medical University</institution>,<addr-line>Szczecin</addr-line>,<country>Poland</country>,</nlm:aff></affiliation></author><author><name sortKey="Gorski, Bohdan" sort="Gorski, Bohdan" uniqKey="Gorski B" first="Bohdan" last="Gorski">Bohdan Gorski</name><affiliation><nlm:aff id="af87"><addr-line>Department of Genetics and Pathology</addr-line>,<institution>International Hereditary Cancer Center, Pomeranian Medical University</institution>,<addr-line>Szczecin</addr-line>,<country>Poland</country>,</nlm:aff></affiliation></author><author><name sortKey="Gronwald, Jacek" sort="Gronwald, Jacek" uniqKey="Gronwald J" first="Jacek" last="Gronwald">Jacek Gronwald</name><affiliation><nlm:aff id="af87"><addr-line>Department of Genetics and Pathology</addr-line>,<institution>International Hereditary Cancer Center, Pomeranian Medical University</institution>,<addr-line>Szczecin</addr-line>,<country>Poland</country>,</nlm:aff></affiliation></author><author><name sortKey="Brennan, Paul" sort="Brennan, Paul" uniqKey="Brennan P" first="Paul" last="Brennan">Paul Brennan</name><affiliation><nlm:aff id="af88"><institution>International agency for Research on Cancer</institution>,<addr-line>Lyon</addr-line>,<country>France</country>,</nlm:aff></affiliation></author><author><name sortKey="Sangrajrang, Suleeporn" sort="Sangrajrang, Suleeporn" uniqKey="Sangrajrang S" first="Suleeporn" last="Sangrajrang">Suleeporn Sangrajrang</name><affiliation><nlm:aff id="af89"><institution>National Cancer Institute</institution>,<addr-line>Bangkok</addr-line>,<country>Thailand</country>,</nlm:aff></affiliation></author><author><name sortKey="Gaborieau, Valerie" sort="Gaborieau, Valerie" uniqKey="Gaborieau V" first="Valerie" last="Gaborieau">Valerie Gaborieau</name><affiliation><nlm:aff id="af88"><institution>International agency for Research on Cancer</institution>,<addr-line>Lyon</addr-line>,<country>France</country>,</nlm:aff></affiliation></author><author><name sortKey="Shen, Chen Yang" sort="Shen, Chen Yang" uniqKey="Shen C" first="Chen-Yang" last="Shen">Chen-Yang Shen</name><affiliation><nlm:aff id="af90"><institution>Institute of Biomedical Sciences, Academia Sinica</institution>,<addr-line>Taipei</addr-line>,<country>Taiwan</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af91"><addr-line>Graduate Institute of Environmental Science</addr-line>,<institution>China Medical University</institution>,<addr-line>Taichung</addr-line>,<country>Taiwan</country>,</nlm:aff></affiliation></author><author><name sortKey="Hsiung, Chia Ni" sort="Hsiung, Chia Ni" uniqKey="Hsiung C" first="Chia-Ni" last="Hsiung">Chia-Ni Hsiung</name><affiliation><nlm:aff id="af90"><institution>Institute of Biomedical Sciences, Academia Sinica</institution>,<addr-line>Taipei</addr-line>,<country>Taiwan</country>,</nlm:aff></affiliation></author><author><name sortKey="Yu, Jyh Cherng" sort="Yu, Jyh Cherng" uniqKey="Yu J" first="Jyh-Cherng" last="Yu">Jyh-Cherng Yu</name><affiliation><nlm:aff wicri:cut=" and" id="af92"><addr-line>Department of Surgery</addr-line></nlm:aff></affiliation></author><author><name sortKey="Chen, Shou Tung" sort="Chen, Shou Tung" uniqKey="Chen S" first="Shou-Tung" last="Chen">Shou-Tung Chen</name><affiliation><nlm:aff id="af94"><addr-line>Department of Surgery</addr-line>,<institution>Changhua Christian Hospital</institution>,<addr-line>Changhua</addr-line>, Taiwan,</nlm:aff></affiliation></author><author><name sortKey="Hsu, Giu Cheng" sort="Hsu, Giu Cheng" uniqKey="Hsu G" first="Giu-Cheng" last="Hsu">Giu-Cheng Hsu</name><affiliation><nlm:aff id="af93"><addr-line>Department of Radiology</addr-line>,<institution>Tri-Service General Hospital</institution>,<addr-line>Taipei</addr-line>, Taiwan,</nlm:aff></affiliation></author><author><name sortKey="Hou, Ming Feng" sort="Hou, Ming Feng" uniqKey="Hou M" first="Ming-Feng" last="Hou">Ming-Feng Hou</name><affiliation><nlm:aff id="af95"><addr-line>Department of Surgery</addr-line>,<institution>Kaohsiung Medical University Hospital</institution>,<addr-line>Kaohsiung</addr-line>, Taiwan,</nlm:aff></affiliation></author><author><name sortKey="Huang, Chiun Sheng" sort="Huang, Chiun Sheng" uniqKey="Huang C" first="Chiun-Sheng" last="Huang">Chiun-Sheng Huang</name><affiliation><nlm:aff id="af96"><addr-line>Department of Surgery</addr-line>,<institution>National Taiwan University Hospital</institution>,<addr-line>Taipei</addr-line>,<country>Taiwan</country>,</nlm:aff></affiliation></author><author><name sortKey="Anton Culver, Hoda" sort="Anton Culver, Hoda" uniqKey="Anton Culver H" first="Hoda" last="Anton-Culver">Hoda Anton-Culver</name><affiliation><nlm:aff id="af97"><addr-line>Department of Epidemiology</addr-line>,<institution>University of California at Irvine</institution>,<addr-line>Irvine, CA 92697</addr-line>,<country>USA</country></nlm:aff></affiliation></author><author><name sortKey="Ziogas, Argyrios" sort="Ziogas, Argyrios" uniqKey="Ziogas A" first="Argyrios" last="Ziogas">Argyrios Ziogas</name><affiliation><nlm:aff id="af97"><addr-line>Department of Epidemiology</addr-line>,<institution>University of California at Irvine</institution>,<addr-line>Irvine, CA 92697</addr-line>,<country>USA</country></nlm:aff></affiliation></author><author><name sortKey="Pharoah, Paul D P" sort="Pharoah, Paul D P" uniqKey="Pharoah P" first="Paul D. P." last="Pharoah">Paul D. P. Pharoah</name><affiliation><nlm:aff wicri:cut=" and" id="af85"><addr-line>Department of Oncology</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af86"><addr-line>Department of Public Health and Primary Care</addr-line>,<institution>University of Cambridge</institution>,<addr-line>Cambridge</addr-line>,<country>UK</country>,</nlm:aff></affiliation></author><author><name sortKey="Garcia Closas, Montserrat" sort="Garcia Closas, Montserrat" uniqKey="Garcia Closas M" first="Montserrat" last="Garcia-Closas">Montserrat Garcia-Closas</name><affiliation><nlm:aff id="af4"><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Rockville, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation><affiliation><nlm:aff wicri:cut=" and" id="af85"><addr-line>Department of Oncology</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af86"><addr-line>Department of Public Health and Primary Care</addr-line>,<institution>University of Cambridge</institution>,<addr-line>Cambridge</addr-line>,<country>UK</country>,</nlm:aff></affiliation></author></analytic><series><title level="j">Human Molecular Genetics</title><idno type="ISSN">0964-6906</idno><idno type="eISSN">1460-2083</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Breast cancers demonstrate substantial biological, clinical and etiological heterogeneity. We investigated breast cancer risk associations of eight susceptibility loci identified in GWAS and two putative susceptibility loci in candidate genes in relation to specific breast tumor subtypes. Subtypes were defined by five markers (ER, PR, HER2, CK5/6, EGFR) and other pathological and clinical features. Analyses included up to 30 040 invasive breast cancer cases and 53 692 controls from 31 studies within the Breast Cancer Association Consortium. We confirmed previous reports of stronger associations with ER+ than ER− tumors for six of the eight loci identified in GWAS: rs2981582 (10q26) (<italic>P</italic>-heterogeneity = 6.1 × 10<sup>−18</sup>), rs3803662 (16q12) (<italic>P</italic> = 3.7 × 10<sup>−5</sup>), rs13281615 (8q24) (<italic>P</italic> = 0.002), rs13387042 (2q35) (<italic>P</italic> = 0.006), rs4973768 (3p24) (<italic>P</italic> = 0.003) and rs6504950 (17q23) (<italic>P</italic> = 0.002)<italic>.</italic> The two candidate loci, <italic>CASP8</italic> (rs1045485, rs17468277) and <italic>TGFB1</italic> (rs1982073), were most strongly related with the risk of PR negative tumors (<italic>P</italic> = 5.1 × 10<sup>−6</sup> and <italic>P</italic> = 4.1 × 10<sup>−4</sup>, respectively), as previously suggested. Four of the eight loci identified in GWAS were associated with triple negative tumors (<italic>P</italic> ≤ 0.016): rs3803662 (16q12), rs889312 (5q11), rs3817198 (11p15) and rs13387042 (2q35); however, only two of them (16q12 and 2q35) were associated with tumors with the core basal phenotype (<italic>P</italic> ≤ 0.002). These analyses are consistent with different biological origins of breast cancers, and indicate that tumor stratification might help in the identification and characterization of novel risk factors for breast cancer subtypes. This may eventually result in further improvements in prevention, early detection and treatment.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Hum Mol Genet</journal-id><journal-id journal-id-type="publisher-id">hmg</journal-id><journal-id journal-id-type="hwp">hmg</journal-id><journal-title-group><journal-title>Human Molecular Genetics</journal-title></journal-title-group><issn pub-type="ppub">0964-6906</issn><issn pub-type="epub">1460-2083</issn><publisher><publisher-name>Oxford University Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">21596841</article-id><article-id pub-id-type="pmc">3140824</article-id><article-id pub-id-type="doi">10.1093/hmg/ddr228</article-id><article-id pub-id-type="publisher-id">ddr228</article-id><article-categories><subj-group subj-group-type="heading"><subject>Association Studies Articles</subject></subj-group></article-categories><title-group><article-title>Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Broeks</surname><given-names>Annegien</given-names></name><xref ref-type="aff" rid="af1">1</xref><xref ref-type="corresp" rid="cor1">*</xref><xref ref-type="author-notes" rid="AN1">†</xref></contrib><contrib contrib-type="author"><name><surname>Schmidt</surname><given-names>Marjanka K.</given-names></name><xref ref-type="aff" rid="af1">1</xref><xref ref-type="aff" rid="af2">2</xref><xref ref-type="author-notes" rid="AN1">†</xref></contrib><contrib contrib-type="author"><name><surname>Sherman</surname><given-names>Mark E.</given-names></name><xref ref-type="aff" rid="af4">4</xref><xref ref-type="author-notes" rid="AN1">†</xref></contrib><contrib contrib-type="author"><name><surname>Couch</surname><given-names>Fergus J.</given-names></name><xref ref-type="aff" rid="af5">5</xref><xref ref-type="aff" rid="af6">6</xref><xref ref-type="author-notes" rid="AN1">†</xref></contrib><contrib contrib-type="author"><name><surname>Hopper</surname><given-names>John L.</given-names></name><xref ref-type="aff" rid="af7">7</xref></contrib><contrib contrib-type="author"><name><surname>Dite</surname><given-names>Gillian S.</given-names></name><xref ref-type="aff" rid="af7">7</xref></contrib><contrib contrib-type="author"><name><surname>Apicella</surname><given-names>Carmel</given-names></name><xref ref-type="aff" rid="af7">7</xref></contrib><contrib contrib-type="author"><name><surname>Smith</surname><given-names>Letitia D.</given-names></name><xref ref-type="aff" rid="af8">8</xref></contrib><contrib contrib-type="author"><name><surname>Hammet</surname><given-names>Fleur</given-names></name><xref ref-type="aff" rid="af8">8</xref></contrib><contrib contrib-type="author"><name><surname>Southey</surname><given-names>Melissa C.</given-names></name><xref ref-type="aff" rid="af8">8</xref></contrib><contrib contrib-type="author"><name><surname>Van ’t Veer</surname><given-names>Laura J.</given-names></name><xref ref-type="aff" rid="af1">1</xref><xref ref-type="aff" rid="af3">3</xref></contrib><contrib contrib-type="author"><name><surname>de Groot</surname><given-names>Renate</given-names></name><xref ref-type="aff" rid="af3">3</xref></contrib><contrib contrib-type="author"><name><surname>Smit</surname><given-names>Vincent T.H.B.M.</given-names></name><xref ref-type="aff" rid="af9">9</xref></contrib><contrib contrib-type="author"><name><surname>Fasching</surname><given-names>Peter A.</given-names></name><xref ref-type="aff" rid="af10">10</xref></contrib><contrib contrib-type="author"><name><surname>Beckmann</surname><given-names>Matthias W.</given-names></name><xref ref-type="aff" rid="af11">11</xref></contrib><contrib contrib-type="author"><name><surname>Jud</surname><given-names>Sebastian</given-names></name><xref ref-type="aff" rid="af11">11</xref></contrib><contrib contrib-type="author"><name><surname>Ekici</surname><given-names>Arif B.</given-names></name><xref ref-type="aff" rid="af14">14</xref></contrib><contrib contrib-type="author"><name><surname>Hartmann</surname><given-names>Arndt</given-names></name><xref ref-type="aff" rid="af12">12</xref></contrib><contrib contrib-type="author"><name><surname>Hein</surname><given-names>Alexander</given-names></name><xref ref-type="aff" rid="af11">11</xref></contrib><contrib contrib-type="author"><name><surname>Schulz-Wendtland</surname><given-names>Ruediger</given-names></name><xref ref-type="aff" rid="af13">13</xref></contrib><contrib contrib-type="author"><name><surname>Burwinkel</surname><given-names>Barbara</given-names></name><xref ref-type="aff" rid="af15">15</xref><xref ref-type="aff" rid="af17">17</xref></contrib><contrib contrib-type="author"><name><surname>Marme</surname><given-names>Frederik</given-names></name><xref ref-type="aff" rid="af15">15</xref></contrib><contrib contrib-type="author"><name><surname>Schneeweiss</surname><given-names>Andreas</given-names></name><xref ref-type="aff" rid="af15">15</xref></contrib><contrib contrib-type="author"><name><surname>Sinn</surname><given-names>Hans-Peter</given-names></name><xref ref-type="aff" rid="af16">16</xref></contrib><contrib contrib-type="author"><name><surname>Sohn</surname><given-names>Christof</given-names></name><xref ref-type="aff" rid="af15">15</xref></contrib><contrib contrib-type="author"><name><surname>Tchatchou</surname><given-names>Sandrine</given-names></name><xref ref-type="aff" rid="af15">15</xref><xref ref-type="aff" rid="af17">17</xref></contrib><contrib contrib-type="author"><name><surname>Bojesen</surname><given-names>Stig E.</given-names></name><xref ref-type="aff" rid="af19">19</xref><xref ref-type="aff" rid="af20">20</xref></contrib><contrib contrib-type="author"><name><surname>Nordestgaard</surname><given-names>Børge G.</given-names></name><xref ref-type="aff" rid="af19">19</xref><xref ref-type="aff" rid="af20">20</xref></contrib><contrib contrib-type="author"><name><surname>Flyger</surname><given-names>Henrik</given-names></name><xref ref-type="aff" rid="af19">19</xref><xref ref-type="aff" rid="af20">20</xref></contrib><contrib contrib-type="author"><name><surname>Ørsted</surname><given-names>David D.</given-names></name><xref ref-type="aff" rid="af19">19</xref><xref ref-type="aff" rid="af20">20</xref></contrib><contrib contrib-type="author"><name><surname>Kaur-Knudsen</surname><given-names>Diljit</given-names></name><xref ref-type="aff" rid="af19">19</xref><xref ref-type="aff" rid="af20">20</xref></contrib><contrib contrib-type="author"><name><surname>Milne</surname><given-names>Roger L.</given-names></name><xref ref-type="aff" rid="af21">21</xref></contrib><contrib contrib-type="author"><name><surname>Pérez</surname><given-names>Jose I. Arias</given-names></name><xref ref-type="aff" rid="af23">23</xref></contrib><contrib contrib-type="author"><name><surname>Zamora</surname><given-names>Pilar</given-names></name><xref ref-type="aff" rid="af25">25</xref></contrib><contrib contrib-type="author"><name><surname>Rodríguez</surname><given-names>Primitiva Menéndez</given-names></name><xref ref-type="aff" rid="af24">24</xref></contrib><contrib contrib-type="author"><name><surname>Benítez</surname><given-names>Javier</given-names></name><xref ref-type="aff" rid="af22">22</xref><xref ref-type="aff" rid="af26">26</xref></contrib><contrib contrib-type="author"><name><surname>Brauch</surname><given-names>Hiltrud</given-names></name><xref ref-type="aff" rid="af27">27</xref><xref ref-type="aff" rid="af28">28</xref></contrib><contrib contrib-type="author"><name><surname>Justenhoven</surname><given-names>Christina</given-names></name><xref ref-type="aff" rid="af27">27</xref><xref ref-type="aff" rid="af28">28</xref></contrib><contrib contrib-type="author"><name><surname>Ko</surname><given-names>Yon-Dschun</given-names></name><xref ref-type="aff" rid="af29">29</xref></contrib><contrib contrib-type="author"><collab>The Genica Network</collab><xref ref-type="aff" rid="af30">30</xref><xref ref-type="aff" rid="af31">31</xref></contrib><contrib contrib-type="author"><name><surname>Hamann</surname><given-names>Ute</given-names></name><xref ref-type="aff" rid="af32">32</xref></contrib><contrib contrib-type="author"><name><surname>Fischer</surname><given-names>Hans-Peter</given-names></name><xref ref-type="aff" rid="af33">33</xref></contrib><contrib contrib-type="author"><name><surname>Brüning</surname><given-names>Thomas</given-names></name><xref ref-type="aff" rid="af34">34</xref></contrib><contrib contrib-type="author"><name><surname>Pesch</surname><given-names>Beate</given-names></name><xref ref-type="aff" rid="af34">34</xref></contrib><contrib contrib-type="author"><name><surname>Chang-Claude</surname><given-names>Jenny</given-names></name><xref ref-type="aff" rid="af18">18</xref></contrib><contrib contrib-type="author"><name><surname>Wang-Gohrke</surname><given-names>Shan</given-names></name><xref ref-type="aff" rid="af35">35</xref></contrib><contrib contrib-type="author"><name><surname>Bremer</surname><given-names>Michael</given-names></name><xref ref-type="aff" rid="af36">36</xref></contrib><contrib contrib-type="author"><name><surname>Karstens</surname><given-names>Johann H.</given-names></name><xref ref-type="aff" rid="af36">36</xref></contrib><contrib contrib-type="author"><name><surname>Hillemanns</surname><given-names>Peter</given-names></name><xref ref-type="aff" rid="af37">37</xref></contrib><contrib contrib-type="author"><name><surname>Dörk</surname><given-names>Thilo</given-names></name><xref ref-type="aff" rid="af37">37</xref></contrib><contrib contrib-type="author"><name><surname>Nevanlinna</surname><given-names>Heli A.</given-names></name><xref ref-type="aff" rid="af38">38</xref></contrib><contrib contrib-type="author"><name><surname>Heikkinen</surname><given-names>Tuomas</given-names></name><xref ref-type="aff" rid="af38">38</xref></contrib><contrib contrib-type="author"><name><surname>Heikkilä</surname><given-names>Päivi</given-names></name><xref ref-type="aff" rid="af40">40</xref></contrib><contrib contrib-type="author"><name><surname>Blomqvist</surname><given-names>Carl</given-names></name><xref ref-type="aff" rid="af41">41</xref></contrib><contrib contrib-type="author"><name><surname>Aittomäki</surname><given-names>Kristiina</given-names></name><xref ref-type="aff" rid="af39">39</xref></contrib><contrib contrib-type="author"><name><surname>Aaltonen</surname><given-names>Kirsimari</given-names></name><xref ref-type="aff" rid="af38">38</xref><xref ref-type="aff" rid="af41">41</xref></contrib><contrib contrib-type="author"><name><surname>Lindblom</surname><given-names>Annika</given-names></name><xref ref-type="aff" rid="af42">42</xref></contrib><contrib contrib-type="author"><name><surname>Margolin</surname><given-names>Sara</given-names></name><xref ref-type="aff" rid="af43">43</xref></contrib><contrib contrib-type="author"><name><surname>Mannermaa</surname><given-names>Arto</given-names></name><xref ref-type="aff" rid="af45">45</xref><xref ref-type="aff" rid="af46">46</xref></contrib><contrib contrib-type="author"><name><surname>Kosma</surname><given-names>Veli-Matti</given-names></name><xref ref-type="aff" rid="af45">45</xref><xref ref-type="aff" rid="af46">46</xref></contrib><contrib contrib-type="author"><name><surname>Kauppinen</surname><given-names>Jaana M.</given-names></name><xref ref-type="aff" rid="af45">45</xref><xref ref-type="aff" rid="af46">46</xref></contrib><contrib contrib-type="author"><name><surname>Kataja</surname><given-names>Vesa</given-names></name><xref ref-type="aff" rid="af47">47</xref></contrib><contrib contrib-type="author"><name><surname>Auvinen</surname><given-names>Päivi</given-names></name><xref ref-type="aff" rid="af48">48</xref></contrib><contrib contrib-type="author"><name><surname>Eskelinen</surname><given-names>Matti</given-names></name><xref ref-type="aff" rid="af49">49</xref></contrib><contrib contrib-type="author"><name><surname>Soini</surname><given-names>Ylermi</given-names></name><xref ref-type="aff" rid="af45">45</xref><xref ref-type="aff" rid="af46">46</xref></contrib><contrib contrib-type="author"><name><surname>Chenevix-Trench</surname><given-names>Georgia</given-names></name><xref ref-type="aff" rid="af50">50</xref></contrib><contrib contrib-type="author"><name><surname>Spurdle</surname><given-names>Amanda B.</given-names></name><xref ref-type="aff" rid="af50">50</xref></contrib><contrib contrib-type="author"><name><surname>Beesley</surname><given-names>Jonathan</given-names></name><xref ref-type="aff" rid="af50">50</xref></contrib><contrib contrib-type="author"><name><surname>Chen</surname><given-names>Xiaoqing</given-names></name><xref ref-type="aff" rid="af50">50</xref></contrib><contrib contrib-type="author"><name><surname>Holland</surname><given-names>Helene</given-names></name><xref ref-type="aff" rid="af50">50</xref></contrib><contrib contrib-type="author"><collab>kConFab</collab><xref ref-type="aff" rid="af51">51</xref></contrib><contrib contrib-type="author"><collab>AOCS</collab><xref ref-type="aff" rid="af50">50</xref><xref ref-type="aff" rid="af51">51</xref></contrib><contrib contrib-type="author"><name><surname>Lambrechts</surname><given-names>Diether</given-names></name><xref ref-type="aff" rid="af52">52</xref></contrib><contrib contrib-type="author"><name><surname>Claes</surname><given-names>Bart</given-names></name><xref ref-type="aff" rid="af52">52</xref></contrib><contrib contrib-type="author"><name><surname>Vandorpe</surname><given-names>Thijs</given-names></name><xref ref-type="aff" rid="af53">53</xref></contrib><contrib contrib-type="author"><name><surname>Neven</surname><given-names>Patrick</given-names></name><xref ref-type="aff" rid="af53">53</xref></contrib><contrib contrib-type="author"><name><surname>Wildiers</surname><given-names>Hans</given-names></name><xref ref-type="aff" rid="af53">53</xref></contrib><contrib contrib-type="author"><name><surname>Flesch-Janys</surname><given-names>Dieter</given-names></name><xref ref-type="aff" rid="af54">54</xref></contrib><contrib contrib-type="author"><name><surname>Hein</surname><given-names>Rebecca</given-names></name><xref ref-type="aff" rid="af18">18</xref></contrib><contrib contrib-type="author"><name><surname>Löning</surname><given-names>Thomas</given-names></name><xref ref-type="aff" rid="af55">55</xref></contrib><contrib contrib-type="author"><name><surname>Kosel</surname><given-names>Matthew</given-names></name><xref ref-type="aff" rid="af5">5</xref><xref ref-type="aff" rid="af6">6</xref></contrib><contrib contrib-type="author"><name><surname>Fredericksen</surname><given-names>Zachary S.</given-names></name><xref ref-type="aff" rid="af5">5</xref><xref ref-type="aff" rid="af6">6</xref></contrib><contrib contrib-type="author"><name><surname>Wang</surname><given-names>Xianshu</given-names></name><xref ref-type="aff" rid="af5">5</xref><xref ref-type="aff" rid="af6">6</xref></contrib><contrib contrib-type="author"><name><surname>Giles</surname><given-names>Graham G.</given-names></name><xref ref-type="aff" rid="af57">57</xref></contrib><contrib contrib-type="author"><name><surname>Baglietto</surname><given-names>Laura</given-names></name><xref ref-type="aff" rid="af58">58</xref></contrib><contrib contrib-type="author"><name><surname>Severi</surname><given-names>Gianluca</given-names></name><xref ref-type="aff" rid="af57">57</xref></contrib><contrib contrib-type="author"><name><surname>McLean</surname><given-names>Catriona</given-names></name><xref ref-type="aff" rid="af58">58</xref></contrib><contrib contrib-type="author"><name><surname>Haiman</surname><given-names>Christopher A.</given-names></name><xref ref-type="aff" rid="af59">59</xref></contrib><contrib contrib-type="author"><name><surname>Henderson</surname><given-names>Brian E.</given-names></name><xref ref-type="aff" rid="af59">59</xref></contrib><contrib contrib-type="author"><name><surname>Le Marchand</surname><given-names>Loic</given-names></name><xref ref-type="aff" rid="af60">60</xref></contrib><contrib contrib-type="author"><name><surname>Kolonel</surname><given-names>Laurence N.</given-names></name><xref ref-type="aff" rid="af60">60</xref></contrib><contrib contrib-type="author"><name><surname>Grenaker Alnæs</surname><given-names>Grethe</given-names></name><xref ref-type="aff" rid="af61">61</xref></contrib><contrib contrib-type="author"><name><surname>Kristensen</surname><given-names>Vessela</given-names></name><xref ref-type="aff" rid="af61">61</xref><xref ref-type="aff" rid="af62">62</xref></contrib><contrib contrib-type="author"><name><surname>Børresen-Dale</surname><given-names>Anne-Lise</given-names></name><xref ref-type="aff" rid="af61">61</xref><xref ref-type="aff" rid="af62">62</xref></contrib><contrib contrib-type="author"><name><surname>Hunter</surname><given-names>David J.</given-names></name><xref ref-type="aff" rid="af63">63</xref><xref ref-type="aff" rid="af64">64</xref></contrib><contrib contrib-type="author"><name><surname>Hankinson</surname><given-names>Susan E.</given-names></name><xref ref-type="aff" rid="af63">63</xref><xref ref-type="aff" rid="af64">64</xref></contrib><contrib contrib-type="author"><name><surname>Andrulis</surname><given-names>Irene L.</given-names></name><xref ref-type="aff" rid="af65">65</xref><xref ref-type="aff" rid="af66">66</xref><xref ref-type="aff" rid="af67">67</xref></contrib><contrib contrib-type="author"><name><surname>Marie Mulligan</surname><given-names>Anna</given-names></name><xref ref-type="aff" rid="af67">67</xref><xref ref-type="aff" rid="af68">68</xref></contrib><contrib contrib-type="author"><name><surname>O'Malley</surname><given-names>Frances P.</given-names></name><xref ref-type="aff" rid="af67">67</xref><xref ref-type="aff" rid="af69">69</xref></contrib><contrib contrib-type="author"><name><surname>Devilee</surname><given-names>Peter</given-names></name><xref ref-type="aff" rid="af70">70</xref></contrib><contrib contrib-type="author"><name><surname>Huijts</surname><given-names>Petra E.A.</given-names></name><xref ref-type="aff" rid="af71">71</xref></contrib><contrib contrib-type="author"><name><surname>Tollenaar</surname><given-names>Rob A.E.M.</given-names></name><xref ref-type="aff" rid="af72">72</xref></contrib><contrib contrib-type="author"><name><surname>Van Asperen</surname><given-names>Christi J.</given-names></name><xref ref-type="aff" rid="af71">71</xref></contrib><contrib contrib-type="author"><name><surname>Seynaeve</surname><given-names>Caroline S.</given-names></name><xref ref-type="aff" rid="af73">73</xref></contrib><contrib contrib-type="author"><name><surname>Chanock</surname><given-names>Stephen J.</given-names></name><xref ref-type="aff" rid="af74">74</xref></contrib><contrib contrib-type="author"><name><surname>Lissowska</surname><given-names>Jolanta</given-names></name><xref ref-type="aff" rid="af75">75</xref></contrib><contrib contrib-type="author"><name><surname>Brinton</surname><given-names>Louise</given-names></name><xref ref-type="aff" rid="af76">76</xref></contrib><contrib contrib-type="author"><name><surname>Peplonska</surname><given-names>Beata</given-names></name><xref ref-type="aff" rid="af77">77</xref></contrib><contrib contrib-type="author"><name><surname>Figueroa</surname><given-names>Jonine</given-names></name><xref ref-type="aff" rid="af4">4</xref></contrib><contrib contrib-type="author"><name><surname>Yang</surname><given-names>Xiaohong R.</given-names></name><xref ref-type="aff" rid="af4">4</xref></contrib><contrib contrib-type="author"><name><surname>Hooning</surname><given-names>Maartje J.</given-names></name><xref ref-type="aff" rid="af78">78</xref></contrib><contrib contrib-type="author"><name><surname>Hollestelle</surname><given-names>Antoinette</given-names></name><xref ref-type="aff" rid="af78">78</xref></contrib><contrib contrib-type="author"><name><surname>Oldenburg</surname><given-names>Rogier A.</given-names></name><xref ref-type="aff" rid="af79">79</xref></contrib><contrib contrib-type="author"><name><surname>Jager</surname><given-names>Agnes</given-names></name><xref ref-type="aff" rid="af78">78</xref></contrib><contrib contrib-type="author"><name><surname>Kriege</surname><given-names>Mieke</given-names></name><xref ref-type="aff" rid="af78">78</xref></contrib><contrib contrib-type="author"><name><surname>Ozturk</surname><given-names>Bahar</given-names></name><xref ref-type="aff" rid="af78">78</xref></contrib><contrib contrib-type="author"><name><surname>van Leenders</surname><given-names>Geert J.L.H.</given-names></name><xref ref-type="aff" rid="af80">80</xref></contrib><contrib contrib-type="author"><name><surname>Hall</surname><given-names>Per</given-names></name><xref ref-type="aff" rid="af44">44</xref></contrib><contrib contrib-type="author"><name><surname>Czene</surname><given-names>Kamila</given-names></name><xref ref-type="aff" rid="af44">44</xref></contrib><contrib contrib-type="author"><name><surname>Humphreys</surname><given-names>Keith</given-names></name><xref ref-type="aff" rid="af44">44</xref></contrib><contrib contrib-type="author"><name><surname>Liu</surname><given-names>Jianjun</given-names></name><xref ref-type="aff" rid="af81">81</xref></contrib><contrib contrib-type="author"><name><surname>Cox</surname><given-names>Angela</given-names></name><xref ref-type="aff" rid="af82">82</xref></contrib><contrib contrib-type="author"><name><surname>Connley</surname><given-names>Daniel</given-names></name><xref ref-type="aff" rid="af82">82</xref></contrib><contrib contrib-type="author"><name><surname>Cramp</surname><given-names>Helen E.</given-names></name><xref ref-type="aff" rid="af82">82</xref></contrib><contrib contrib-type="author"><name><surname>Cross</surname><given-names>Simon S.</given-names></name><xref ref-type="aff" rid="af83">83</xref></contrib><contrib contrib-type="author"><name><surname>Balasubramanian</surname><given-names>Sabapathy P.</given-names></name><xref ref-type="aff" rid="af84">84</xref></contrib><contrib contrib-type="author"><name><surname>Reed</surname><given-names>Malcolm W.R.</given-names></name><xref ref-type="aff" rid="af84">84</xref></contrib><contrib contrib-type="author"><name><surname>Dunning</surname><given-names>Alison M.</given-names></name><xref ref-type="aff" rid="af85">85</xref></contrib><contrib contrib-type="author"><name><surname>Easton</surname><given-names>Douglas F.</given-names></name><xref ref-type="aff" rid="af86">86</xref></contrib><contrib contrib-type="author"><name><surname>Humphreys</surname><given-names>Manjeet K.</given-names></name><xref ref-type="aff" rid="af86">86</xref></contrib><contrib contrib-type="author"><name><surname>Caldas</surname><given-names>Carlos</given-names></name><xref ref-type="aff" rid="af85">85</xref></contrib><contrib contrib-type="author"><name><surname>Blows</surname><given-names>Fiona</given-names></name><xref ref-type="aff" rid="af85">85</xref></contrib><contrib contrib-type="author"><name><surname>Driver</surname><given-names>Kristy</given-names></name><xref ref-type="aff" rid="af85">85</xref></contrib><contrib contrib-type="author"><name><surname>Provenzano</surname><given-names>Elena</given-names></name><xref ref-type="aff" rid="af85">85</xref></contrib><contrib contrib-type="author"><name><surname>Lubinski</surname><given-names>Jan</given-names></name><xref ref-type="aff" rid="af87">87</xref></contrib><contrib contrib-type="author"><name><surname>Jakubowska</surname><given-names>Anna</given-names></name><xref ref-type="aff" rid="af87">87</xref></contrib><contrib contrib-type="author"><name><surname>Huzarski</surname><given-names>Tomasz</given-names></name><xref ref-type="aff" rid="af87">87</xref></contrib><contrib contrib-type="author"><name><surname>Byrski</surname><given-names>Tomasz</given-names></name><xref ref-type="aff" rid="af87">87</xref></contrib><contrib contrib-type="author"><name><surname>Cybulski</surname><given-names>Cezary</given-names></name><xref ref-type="aff" rid="af87">87</xref></contrib><contrib contrib-type="author"><name><surname>Gorski</surname><given-names>Bohdan</given-names></name><xref ref-type="aff" rid="af87">87</xref></contrib><contrib contrib-type="author"><name><surname>Gronwald</surname><given-names>Jacek</given-names></name><xref ref-type="aff" rid="af87">87</xref></contrib><contrib contrib-type="author"><name><surname>Brennan</surname><given-names>Paul</given-names></name><xref ref-type="aff" rid="af88">88</xref></contrib><contrib contrib-type="author"><name><surname>Sangrajrang</surname><given-names>Suleeporn</given-names></name><xref ref-type="aff" rid="af89">89</xref></contrib><contrib contrib-type="author"><name><surname>Gaborieau</surname><given-names>Valerie</given-names></name><xref ref-type="aff" rid="af88">88</xref></contrib><contrib contrib-type="author"><name><surname>Shen</surname><given-names>Chen-Yang</given-names></name><xref ref-type="aff" rid="af90">90</xref><xref ref-type="aff" rid="af91">91</xref></contrib><contrib contrib-type="author"><name><surname>Hsiung</surname><given-names>Chia-Ni</given-names></name><xref ref-type="aff" rid="af90">90</xref></contrib><contrib contrib-type="author"><name><surname>Yu</surname><given-names>Jyh-Cherng</given-names></name><xref ref-type="aff" rid="af92">92</xref></contrib><contrib contrib-type="author"><name><surname>Chen</surname><given-names>Shou-Tung</given-names></name><xref ref-type="aff" rid="af94">94</xref></contrib><contrib contrib-type="author"><name><surname>Hsu</surname><given-names>Giu-Cheng</given-names></name><xref ref-type="aff" rid="af93">93</xref></contrib><contrib contrib-type="author"><name><surname>Hou</surname><given-names>Ming-Feng</given-names></name><xref ref-type="aff" rid="af95">95</xref></contrib><contrib contrib-type="author"><name><surname>Huang</surname><given-names>Chiun-Sheng</given-names></name><xref ref-type="aff" rid="af96">96</xref></contrib><contrib contrib-type="author"><name><surname>Anton-Culver</surname><given-names>Hoda</given-names></name><xref ref-type="aff" rid="af97">97</xref></contrib><contrib contrib-type="author"><name><surname>Ziogas</surname><given-names>Argyrios</given-names></name><xref ref-type="aff" rid="af97">97</xref></contrib><contrib contrib-type="author"><name><surname>Pharoah</surname><given-names>Paul D.P.</given-names></name><xref ref-type="aff" rid="af85">85</xref><xref ref-type="aff" rid="af86">86</xref><xref ref-type="author-notes" rid="AN1">†</xref></contrib><contrib contrib-type="author"><name><surname>Garcia-Closas</surname><given-names>Montserrat</given-names></name><xref ref-type="aff" rid="af4">4</xref><xref ref-type="aff" rid="af85">85</xref><xref ref-type="aff" rid="af86">86</xref><xref ref-type="author-notes" rid="AN1">†</xref></contrib></contrib-group><aff id="af1"><label>1</label><addr-line>Department of Experimental Therapy</addr-line>,</aff><aff id="af2"><label>2</label><addr-line>Department of Epidemiology</addr-line> and</aff><aff id="af3"><label>3</label><addr-line>Department of Molecular Pathology</addr-line>,<institution>The Netherlands Cancer Institute</institution>,<addr-line>Amsterdam</addr-line>,<country>the Netherlands</country>,</aff><aff id="af4"><label>4</label><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Rockville, MD</addr-line>,<country>USA</country>,</aff><aff id="af5"><label>5</label><addr-line>Department of Laboratory Medicine and Pathology</addr-line> and</aff><aff id="af6"><label>6</label><addr-line>Department of Health Sciences Research</addr-line>,<institution>Mayo Clinic</institution>,<addr-line>Rochester, MN</addr-line>,<country>USA</country>,</aff><aff id="af7"><label>7</label><institution>Centre for Molecular, Environmental, Genetic and Analytic Epidemiology</institution> and</aff><aff id="af8"><label>8</label><addr-line>Genetic Epidemiology Laboratory, Department of Pathology</addr-line>,<institution>The University of Melbourne</institution>,<country>Australia</country>,</aff><aff id="af9"><label>9</label><addr-line>Department of Pathology</addr-line>,<institution>Leiden University Medical Centre</institution>,<addr-line>Leiden</addr-line>,<country>the Netherlands</country>,</aff><aff id="af10"><label>10</label><addr-line>Division of Hematology and Oncology, David Geffen School of Medicine</addr-line>,<institution>University of California at Los Angeles</institution>,<addr-line>Los Angeles, CA</addr-line>,<country>USA</country>,</aff><aff id="af11"><label>11</label><addr-line>Department of Gynecology and Obstetrics</addr-line>,</aff><aff id="af12"><label>12</label><addr-line>Institute of Pathology</addr-line>,</aff><aff id="af13"><label>13</label><addr-line>Institute of Radiology</addr-line>,<institution>University Breast Center</institution>,<institution>University Hospital Erlangen</institution>,<addr-line>Erlangen</addr-line>,<country>Germany</country>,</aff><aff id="af14"><label>14</label><addr-line>Institute of Human Genetics</addr-line>,<institution>Friedrich Alexander University Erlangen</institution>,<addr-line>Nürnberg</addr-line>,<country>Germany</country>,</aff><aff id="af15"><label>15</label><addr-line>Department of Gynecology and Obstetrics</addr-line> and</aff><aff id="af16"><label>16</label><addr-line>Department of Pathology</addr-line>,<institution>University Hospital Heidelberg</institution>,<addr-line>Heidelberg</addr-line>,<country>Germany</country>,</aff><aff id="af17"><label>17</label><addr-line>Molecular Epidemiology</addr-line> and</aff><aff id="af18"><label>18</label><addr-line>Division of Cancer Epidemiology</addr-line>,<institution>German Cancer Research Center</institution>,<addr-line>Heidelberg</addr-line>,<country>Germany</country>,</aff><aff id="af19"><label>19</label><addr-line>Department of Clinical Biochemistry</addr-line> and</aff><aff id="af20"><label>20</label><addr-line>Department of Breast Surgery</addr-line>,<institution>Herlev University Hospital</institution>,<institution>University of Copenhagen</institution>, Copenhagen,<country>Denmark</country>,</aff><aff id="af21"><label>21</label><addr-line>Genetic & Molecular Epidemiology Group</addr-line> and</aff><aff id="af22"><label>22</label><addr-line>Human Cancer Genetic Group</addr-line>,<institution>Spanish National Cancer Research Centre (CNIO)</institution>,<addr-line>Madrid</addr-line>,<country>Spain</country>,</aff><aff id="af23"><label>23</label><addr-line>Servicio Cirugía General</addr-line> and</aff><aff id="af24"><label>24</label><addr-line>Servicio de Anatomía Patológica</addr-line>,<institution>Hospital Monte Naranco</institution>,<addr-line>Oviedo</addr-line>,<country>Spain</country>,</aff><aff id="af25"><label>25</label><addr-line>Servicio de Oncología Médica</addr-line>,<institution>Hospital La Paz</institution>,<addr-line>Madrid</addr-line>,<country>Spain</country>,</aff><aff id="af26"><label>26</label><institution>CIBERER</institution>,<addr-line>Madrid</addr-line>,<country>Spain</country>,</aff><aff id="af27"><label>27</label><institution>Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology</institution>,<addr-line>Stuttgart</addr-line>,<country>Germany</country>,</aff><aff id="af28"><label>28</label><institution>University Tübingen</institution>,<addr-line>Tübingen</addr-line>,<country>Germany</country>,</aff><aff id="af29"><label>29</label><addr-line>Department of Internal Medicine</addr-line>,<institution>Evangelische Kliniken Bonn gGmbH</institution>,<addr-line>Johanniter Krankenhaus, Bonn</addr-line>,<country>Germany</country>,</aff><aff id="af30"><label>30</label><addr-line>Institute of Pathology</addr-line>,<institution>Medical Faculty of the University of Bonn</institution>,<country>Germany</country>,</aff><aff id="af31"><label>31</label><addr-line>BGFA - Research Institute of Occupational Medicine of the German Social Accident Insurance</addr-line>,<institution>Ruhr University Bochum</institution>,<country>Germany</country>,</aff><aff id="af32"><label>32</label><addr-line>Molecular Genetics of Breast Cancer</addr-line>,<institution>Deutsches Krebsforschungszentrum (DKFZ)</institution>,<addr-line>Heidelberg</addr-line>,<country>Germany</country>,</aff><aff id="af33"><label>33</label><institution>Institute of Pathology, Medical Faculty of the University of Bonn</institution>,<addr-line>Bonn</addr-line>,<country>Germany</country>,</aff><aff id="af34"><label>34</label><institution>Institute of Prevention and Occupational Medicine of the German Social Accident Insurance (IPA)</institution>,<addr-line>Bochum</addr-line>,<country>Germany</country>,</aff><aff id="af35"><label>35</label><addr-line>Department of Obstetrics and Gynecology</addr-line>,<institution>University of Ulm</institution>,<addr-line>Ulm</addr-line>,<country>Germany</country>,</aff><aff id="af36"><label>36</label><addr-line>Hannover Medical School</addr-line>,<institution>Clinics of Radiation Oncology</institution>,<addr-line>Hannover</addr-line>,<country>Germany</country>,</aff><aff id="af37"><label>37</label><institution>Clinics of Obstetrics and Gynaecology</institution>,<addr-line>Hannover</addr-line>,<country>Germany</country>,</aff><aff id="af38"><label>38</label><addr-line>Department of Obstetrics and Gynecology</addr-line>,</aff><aff id="af39"><label>39</label><addr-line>Department of Clinical Genetics</addr-line>,</aff><aff id="af40"><label>40</label><addr-line>Department of Pathology</addr-line> and</aff><aff id="af41"><label>41</label><addr-line>Department of Oncology</addr-line>,<institution>Helsinki University Central Hospital</institution>,<addr-line>Helsinki</addr-line>,<country>Finland</country>,</aff><aff id="af42"><label>42</label><addr-line>Department of Molecular Medicine and Surgery,</addr-line></aff><aff id="af43"><label>43</label><addr-line>Department of Oncology and Pathology</addr-line> and</aff><aff id="af44"><label>44</label><addr-line>Department of Medical Epidemiology and Biostatistics</addr-line>,<institution>Karolinska Institute</institution>,<addr-line>Stockholm</addr-line>,<country>Sweden</country>,</aff><aff id="af45"><label>45</label><addr-line>Department of Pathology</addr-line>,<institution>Institute of Clinical Medicine, University of Eastern Finland and Kuopio University Hospital</institution>, Kuopio,<country>Finland</country>,</aff><aff id="af46"><label>46</label><institution>Biocenter Kuopio</institution>,<addr-line>Kuopio</addr-line>,<country>Finland</country>,</aff><aff id="af47"><label>47</label><addr-line>Department of Oncology</addr-line>,<institution>Vaasa Central Hospital</institution>,<addr-line>Vaasa</addr-line>,<country>Finland</country>,</aff><aff id="af48"><label>48</label><addr-line>Department of Oncology</addr-line> and</aff><aff id="af49"><label>49</label><addr-line>Department of Surgery</addr-line>,<institution>Kuopio University Hospital</institution>,<addr-line>Kuopio</addr-line>,<country>Finland</country>,</aff><aff id="af50"><label>50</label><institution>Queensland Institute of Medical Research</institution>,<addr-line>Brisbane</addr-line>,<country>Australia</country>,</aff><aff id="af51"><label>51</label><institution>Peter MacCallum Cancer Centre</institution>,<addr-line>Melbourne</addr-line>,<country>Australia</country>,</aff><aff id="af52"><label>52</label><institution>Vesalius Research Center</institution>,<addr-line>KU Leuven and VIB, Leuven</addr-line>,<country>Belgium</country>,</aff><aff id="af53"><label>53</label><addr-line>Multidisciplinary Breast Center</addr-line>,<institution>University Hospitals Leuven</institution>,<country>Belgium</country>,</aff><aff id="af54"><label>54</label><addr-line>Institute for Medical Biometrics and Epidemiology</addr-line>,<institution>University Clinic Hamburg-Eppendorf</institution>,<country>Germany</country>,</aff><aff id="af55"><label>55</label><addr-line>Albertinen Pathology Department, Hamburg</addr-line>,<country>Germany</country>,</aff><aff id="af56"><label>56</label><addr-line>Department of Pathology</addr-line>,<institution>University Hospital</institution>,<addr-line>Heidelberg</addr-line>,<country>Germany</country>,</aff><aff id="af57"><label>57</label><addr-line>Cancer Epidemiology Centre</addr-line>,<institution>The Cancer Council Victoria</institution>,<addr-line>Melbourne</addr-line>,<country>Australia</country>,</aff><aff id="af58"><label>58</label><addr-line>Department of Anatomical Pathology</addr-line>,<institution>Alfred Hospital</institution>,<addr-line>Melbourne</addr-line>,<country>Australia</country>,</aff><aff id="af59"><label>59</label><addr-line>Department of Preventive Medicine, Keck School of Medicine and Norris Comprehensive Cancer Center</addr-line>,<institution>University of Southern California</institution>,<addr-line>Los Angeles, CA 90089</addr-line>, USA,</aff><aff id="af60"><label>60</label><addr-line>Epidemiology Program</addr-line>,<institution>Cancer Research Center, University of Hawaii</institution>,<addr-line>Honolulu, HI 96813</addr-line>,<country>USA</country>,</aff><aff id="af61"><label>61</label><addr-line>Department of Genetics</addr-line>,<institution>Institute for Cancer Research, Oslo University Hospital</institution>,<addr-line>Radiumhospitalet, Montebello 0310, Oslo</addr-line>,<country>Norway</country>,</aff><aff id="af62"><label>62</label><addr-line>Faculty of Medicine</addr-line><institution>(Faculty Division Ahus)</institution>,<addr-line>UiO</addr-line>,<country>Norway</country>,</aff><aff id="af63"><label>63</label><addr-line>Channing Laboratory, Department of Medicine</addr-line>,<institution>Brigham and Womens Hospital and Harvard Medical school</institution>, Boston, MA, USA,</aff><aff id="af64"><label>64</label><addr-line>Department of Epidemiology</addr-line>,<institution>Harvard school of public health</institution>,<addr-line>Boston, MA</addr-line>,<country>USA</country>,</aff><aff id="af65"><label>65</label><institution>Samuel Lunenfeld Research Institute, Mount Sinai Hospital</institution>,<addr-line>Ontario Cancer Genetics Network, Cancer Care Ontario, Ontario</addr-line>,<country>Canada</country>,</aff><aff id="af66"><label>66</label><addr-line>Department of Molecular Genetics and</addr-line></aff><aff id="af67"><label>67</label><addr-line>Laboratory Medicine</addr-line> and<addr-line>Pathobiology</addr-line>,<institution>University of Toronto</institution>,<addr-line>Toronto, Ontario</addr-line>,<country>Canada</country>,</aff><aff id="af68"><label>68</label><addr-line>Keenan Research Centre</addr-line>,<institution>Li Ka Shing Knowledge Institute of St Michael's Hospital</institution>,<addr-line>Toronto, Ontario</addr-line>,<country>Canada</country>,</aff><aff id="af69"><label>69</label><addr-line>The Department of Laboratory Medicine and the</addr-line><institution>Keenan Research Centre of the Li Ka Shing Knowledge Institute, St Michael's Hospital,</institution><addr-line>Toronto, Ontario</addr-line>,<country>Canada</country></aff><aff id="af70"><label>70</label><addr-line>Department Human Genetics & Department of Pathology</addr-line>,</aff><aff id="af71"><label>71</label><addr-line>Clinical Genetics</addr-line> and</aff><aff id="af72"><label>72</label><addr-line>Surgical Oncology</addr-line>,<institution>Leiden University Medical Center</institution>,<addr-line>Leiden</addr-line>,<country>The Netherlands</country>,</aff><aff id="af73"><label>73</label><addr-line>Department of Medical Oncology</addr-line>,<institution>Rotterdam Family Cancer Clinic, Erasmus MC-Daniel den Hoed Cancer Center</institution>,<addr-line>Rotterdam</addr-line>,<country>The Netherlands</country>,</aff><aff id="af74"><label>74</label><addr-line>Advanced Technology Center</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Gaithersburg, MD 20892-4605</addr-line>,<country>USA</country>,</aff><aff id="af75"><label>75</label><addr-line>Department of Cancer Epidemiology and Prevention</addr-line>,<institution>Cancer Center and M. Sklodowska-Curie Institute of Oncology</institution>,<addr-line>02-781 Warsaw</addr-line>,<country>Poland</country>,</aff><aff id="af76"><label>76</label><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Rockville, MD 20852-7234</addr-line>,<country>USA</country>,</aff><aff id="af77"><label>77</label><institution>Nofer Institute of Occupational Medicine</institution>,<addr-line>91-348 Lodz</addr-line>,<country>Poland</country>,</aff><aff id="af78"><label>78</label><addr-line>Department of Medical Oncology</addr-line>,</aff><aff id="af79"><label>79</label><addr-line>Department of Clinical Genetics</addr-line> and</aff><aff id="af80"><label>80</label><addr-line>Department of Pathology</addr-line>,<institution>Rotterdam Family Cancer Clinic, Erasmus University Medical Center</institution>,<addr-line>Rotterdam</addr-line>,<country>the Netherlands</country>,</aff><aff id="af81"><label>81</label><addr-line>Human Genetics Laboratory</addr-line>,<institution>Genome Institute of Singapore</institution>,<country>Singapore</country>,</aff><aff id="af82"><label>82</label><addr-line>Department of Oncology, Institute for Cancer Studies</addr-line>,</aff><aff id="af83"><label>83</label><addr-line>Academic Unit of Pathology, Department of Oncology</addr-line> and</aff><aff id="af84"><label>84</label><addr-line>Academic Unit of Surgical Oncology, Department of Oncology</addr-line>,<institution>University of Sheffield Medical School</institution>,<addr-line>Sheffield</addr-line>,<country>UK</country>,</aff><aff id="af85"><label>85</label><addr-line>Department of Oncology</addr-line> and</aff><aff id="af86"><label>86</label><addr-line>Department of Public Health and Primary Care</addr-line>,<institution>University of Cambridge</institution>,<addr-line>Cambridge</addr-line>,<country>UK</country>,</aff><aff id="af87"><label>87</label><addr-line>Department of Genetics and Pathology</addr-line>,<institution>International Hereditary Cancer Center, Pomeranian Medical University</institution>,<addr-line>Szczecin</addr-line>,<country>Poland</country>,</aff><aff id="af88"><label>88</label><institution>International agency for Research on Cancer</institution>,<addr-line>Lyon</addr-line>,<country>France</country>,</aff><aff id="af89"><label>89</label><institution>National Cancer Institute</institution>,<addr-line>Bangkok</addr-line>,<country>Thailand</country>,</aff><aff id="af90"><label>90</label><institution>Institute of Biomedical Sciences, Academia Sinica</institution>,<addr-line>Taipei</addr-line>,<country>Taiwan</country>,</aff><aff id="af91"><label>91</label><addr-line>Graduate Institute of Environmental Science</addr-line>,<institution>China Medical University</institution>,<addr-line>Taichung</addr-line>,<country>Taiwan</country>,</aff><aff id="af92"><label>92</label><addr-line>Department of Surgery</addr-line> and</aff><aff id="af93"><label>93</label><addr-line>Department of Radiology</addr-line>,<institution>Tri-Service General Hospital</institution>,<addr-line>Taipei</addr-line>, Taiwan,</aff><aff id="af94"><label>94</label><addr-line>Department of Surgery</addr-line>,<institution>Changhua Christian Hospital</institution>,<addr-line>Changhua</addr-line>, Taiwan,</aff><aff id="af95"><label>95</label><addr-line>Department of Surgery</addr-line>,<institution>Kaohsiung Medical University Hospital</institution>,<addr-line>Kaohsiung</addr-line>, Taiwan,</aff><aff id="af96"><label>96</label><addr-line>Department of Surgery</addr-line>,<institution>National Taiwan University Hospital</institution>,<addr-line>Taipei</addr-line>,<country>Taiwan</country>,</aff><aff id="af97"><label>97</label><addr-line>Department of Epidemiology</addr-line>,<institution>University of California at Irvine</institution>,<addr-line>Irvine, CA 92697</addr-line>,<country>USA</country></aff><author-notes><corresp id="cor1"><label>*</label>To whom correspondence should be addressed at: Division of Experimental Therapy C2, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands. Tel: +31 205122037; Fax: +31 205122035; Email: <email>a.broeks@nki.nl</email></corresp><fn id="AN1"><label>†</label><p>The authors wish it to be known that, in their opinion, the first four authors should be regarded as joint First Authors and together with the last two as the writing group.</p></fn></author-notes><pub-date pub-type="ppub"><day>15</day><month>8</month><year>2011</year></pub-date><pub-date pub-type="epub"><day>19</day><month>5</month><year>2011</year></pub-date><pub-date pub-type="pmc-release"><day>15</day><month>8</month><year>2012</year></pub-date><pmc-comment> PMC Release delay is 12 months and 0 days and was based on the
<volume>20</volume><issue>16</issue><fpage>3289</fpage><lpage>3303</lpage><history><date date-type="received"><day>17</day><month>12</month><year>2010</year></date><date date-type="rev-recd"><day>10</day><month>5</month><year>2011</year></date><date date-type="accepted"><day>16</day><month>5</month><year>2011</year></date></history><permissions><copyright-statement>© The Author 2011. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com</copyright-statement><copyright-year>2011</copyright-year></permissions><self-uri content-type="pdf" xlink:type="simple" xlink:href="ddr228.pdf"></self-uri><abstract><p>Breast cancers demonstrate substantial biological, clinical and etiological heterogeneity. We investigated breast cancer risk associations of eight susceptibility loci identified in GWAS and two putative susceptibility loci in candidate genes in relation to specific breast tumor subtypes. Subtypes were defined by five markers (ER, PR, HER2, CK5/6, EGFR) and other pathological and clinical features. Analyses included up to 30 040 invasive breast cancer cases and 53 692 controls from 31 studies within the Breast Cancer Association Consortium. We confirmed previous reports of stronger associations with ER+ than ER− tumors for six of the eight loci identified in GWAS: rs2981582 (10q26) (<italic>P</italic>-heterogeneity = 6.1 × 10<sup>−18</sup>), rs3803662 (16q12) (<italic>P</italic> = 3.7 × 10<sup>−5</sup>), rs13281615 (8q24) (<italic>P</italic> = 0.002), rs13387042 (2q35) (<italic>P</italic> = 0.006), rs4973768 (3p24) (<italic>P</italic> = 0.003) and rs6504950 (17q23) (<italic>P</italic> = 0.002)<italic>.</italic> The two candidate loci, <italic>CASP8</italic> (rs1045485, rs17468277) and <italic>TGFB1</italic> (rs1982073), were most strongly related with the risk of PR negative tumors (<italic>P</italic> = 5.1 × 10<sup>−6</sup> and <italic>P</italic> = 4.1 × 10<sup>−4</sup>, respectively), as previously suggested. Four of the eight loci identified in GWAS were associated with triple negative tumors (<italic>P</italic> ≤ 0.016): rs3803662 (16q12), rs889312 (5q11), rs3817198 (11p15) and rs13387042 (2q35); however, only two of them (16q12 and 2q35) were associated with tumors with the core basal phenotype (<italic>P</italic> ≤ 0.002). These analyses are consistent with different biological origins of breast cancers, and indicate that tumor stratification might help in the identification and characterization of novel risk factors for breast cancer subtypes. This may eventually result in further improvements in prevention, early detection and treatment.</p></abstract></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Pmc/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001881 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Corpus/biblio.hfd -nk 001881 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Asie
|area= AustralieFrV1
|flux= Pmc
|étape= Corpus
|type= RBID
|clé=
|texte=
}}
| This area was generated with Dilib version V0.6.33. |  |