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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">19p13.1 is a triple negative-specific breast cancer susceptibility locus</title><author><name sortKey="Stevens, Kristen N" sort="Stevens, Kristen N" uniqKey="Stevens K" first="Kristen N." last="Stevens">Kristen N. Stevens</name><affiliation><nlm:aff id="A1">Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota</nlm:aff></affiliation></author><author><name sortKey="Fredericksen, Zachary" sort="Fredericksen, Zachary" uniqKey="Fredericksen Z" first="Zachary" last="Fredericksen">Zachary Fredericksen</name><affiliation><nlm:aff id="A1">Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota</nlm:aff></affiliation></author><author><name sortKey="Vachon, Celine M" sort="Vachon, Celine M" uniqKey="Vachon C" first="Celine M." last="Vachon">Celine M. Vachon</name><affiliation><nlm:aff id="A1">Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota</nlm:aff></affiliation></author><author><name sortKey="Wang, Xianshu" sort="Wang, Xianshu" uniqKey="Wang X" first="Xianshu" last="Wang">Xianshu Wang</name><affiliation><nlm:aff id="A2">Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota</nlm:aff></affiliation></author><author><name sortKey="Margolin, Sara" sort="Margolin, Sara" uniqKey="Margolin S" first="Sara" last="Margolin">Sara Margolin</name><affiliation><nlm:aff id="A3">Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden</nlm:aff></affiliation></author><author><name sortKey="Lindblom, Annika" sort="Lindblom, Annika" uniqKey="Lindblom A" first="Annika" last="Lindblom">Annika Lindblom</name><affiliation><nlm:aff id="A3">Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden</nlm:aff></affiliation></author><author><name sortKey="Nevanlinna, Heli" sort="Nevanlinna, Heli" uniqKey="Nevanlinna H" first="Heli" last="Nevanlinna">Heli Nevanlinna</name><affiliation><nlm:aff id="A4">Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Biomedicum Helsinki, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Greco, Dario" sort="Greco, Dario" uniqKey="Greco D" first="Dario" last="Greco">Dario Greco</name><affiliation><nlm:aff id="A4">Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Biomedicum Helsinki, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Aittom Ki, Kristiina" sort="Aittom Ki, Kristiina" uniqKey="Aittom Ki K" first="Kristiina" last="Aittom Ki">Kristiina Aittom Ki</name><affiliation><nlm:aff id="A5">Department of Clinical Genetics, Helsinki University Central Hospital, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Blomqvist, Carl" sort="Blomqvist, Carl" uniqKey="Blomqvist C" first="Carl" last="Blomqvist">Carl Blomqvist</name><affiliation><nlm:aff id="A6">Department of Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Chang Claude, Jenny" sort="Chang Claude, Jenny" uniqKey="Chang Claude J" first="Jenny" last="Chang-Claude">Jenny Chang-Claude</name><affiliation><nlm:aff id="A7">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Vrieling, Alina" sort="Vrieling, Alina" uniqKey="Vrieling A" first="Alina" last="Vrieling">Alina Vrieling</name><affiliation><nlm:aff id="A7">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Flesch Janys, Dieter" sort="Flesch Janys, Dieter" uniqKey="Flesch Janys D" first="Dieter" last="Flesch-Janys">Dieter Flesch-Janys</name><affiliation><nlm:aff id="A8">Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg, Germany</nlm:aff></affiliation></author><author><name sortKey="Sinn, Hans Peter" sort="Sinn, Hans Peter" uniqKey="Sinn H" first="Hans-Peter" last="Sinn">Hans-Peter Sinn</name><affiliation><nlm:aff id="A9">Department of Pathology, University Hospital Heidelberg, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Wang Gohrke, Shan" sort="Wang Gohrke, Shan" uniqKey="Wang Gohrke S" first="Shan" last="Wang-Gohrke">Shan Wang-Gohrke</name><affiliation><nlm:aff id="A10">Department of Obstetrics and Gynecology, University of Ulm, Ulm, Germany</nlm:aff></affiliation></author><author><name sortKey="Nickels, Stefan" sort="Nickels, Stefan" uniqKey="Nickels S" first="Stefan" last="Nickels">Stefan Nickels</name><affiliation><nlm:aff id="A7">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Brauch, Hiltrud" sort="Brauch, Hiltrud" uniqKey="Brauch H" first="Hiltrud" last="Brauch">Hiltrud Brauch</name><affiliation><nlm:aff id="A11">Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A12">University of Tubingen, Tubingen, Germany</nlm:aff></affiliation></author><author><name sortKey="Ko, Yon Dschun" sort="Ko, Yon Dschun" uniqKey="Ko Y" first="Yon-Dschun" last="Ko">Yon-Dschun Ko</name><affiliation><nlm:aff id="A13">Department of Internal Medicine, Evangelische Kliniken Bonn gGmbH, Johanniter Krankenhaus, Bonn, Germany</nlm:aff></affiliation></author><author><name sortKey="Fischer, Hans Peter" sort="Fischer, Hans Peter" uniqKey="Fischer H" first="Hans-Peter" last="Fischer">Hans-Peter Fischer</name><affiliation><nlm:aff id="A14">Institute of Pathology, Medical Faculty of the University of Bonn, Bonn, Germany</nlm:aff></affiliation></author><author><name sortKey="Schmutzler, Rita K" sort="Schmutzler, Rita K" uniqKey="Schmutzler R" first="Rita K." last="Schmutzler">Rita K. Schmutzler</name><affiliation><nlm:aff id="A17">Division of Molecular Gyneco-Oncology, Department of Gynaecology and Obstetrics, Center of Molecular Medicine Cologne (CMMC), University Hospital of Cologne, Cologne, Germany</nlm:aff></affiliation></author><author><name sortKey="Meindl, Alfons" sort="Meindl, Alfons" uniqKey="Meindl A" first="Alfons" last="Meindl">Alfons Meindl</name><affiliation><nlm:aff id="A18">Department for Obstetrica and Gynaecology, Dvision for Tumor Genetics, Klinikum rechts der Isar, Technische Universität, Munich, Germany</nlm:aff></affiliation></author><author><name sortKey="Bartram, Claus R" sort="Bartram, Claus R" uniqKey="Bartram C" first="Claus R." last="Bartram">Claus R. Bartram</name><affiliation><nlm:aff id="A19">Institute of Human Genetics, University of Heidelberg, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Schott, Sarah" sort="Schott, Sarah" uniqKey="Schott S" first="Sarah" last="Schott">Sarah Schott</name><affiliation><nlm:aff id="A20">Department of Obstetrics and Gynecology, University Hospital Heidelberg, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Engel, Christof" sort="Engel, Christof" uniqKey="Engel C" first="Christof" last="Engel">Christof Engel</name><affiliation><nlm:aff id="A21">Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany</nlm:aff></affiliation></author><author><name sortKey="Godwin, Andrew K" sort="Godwin, Andrew K" uniqKey="Godwin A" first="Andrew K." last="Godwin">Andrew K. Godwin</name><affiliation><nlm:aff id="A22">Department of Pathology & Laboratory Medicine, University of Kansas Medical Center, Kansas City, USA</nlm:aff></affiliation></author><author><name sortKey="Weaver, Joellen" sort="Weaver, Joellen" uniqKey="Weaver J" first="Joellen" last="Weaver">Joellen Weaver</name><affiliation><nlm:aff id="A23">Biosample Repository, Fox Chase Cancer Center, Philadelphia, USA</nlm:aff></affiliation></author><author><name sortKey="Pathak, Harsh B" sort="Pathak, Harsh B" uniqKey="Pathak H" first="Harsh B." last="Pathak">Harsh B. Pathak</name><affiliation><nlm:aff id="A22">Department of Pathology & Laboratory Medicine, University of Kansas Medical Center, Kansas City, USA</nlm:aff></affiliation></author><author><name sortKey="Sharma, Priyanka" sort="Sharma, Priyanka" uniqKey="Sharma P" first="Priyanka" last="Sharma">Priyanka Sharma</name><affiliation><nlm:aff id="A24">Division of Hematology and Oncology, University of Kansas Medical Center, Kansas City, USA</nlm:aff></affiliation></author><author><name sortKey="Brenner, Hermann" sort="Brenner, Hermann" uniqKey="Brenner H" first="Hermann" last="Brenner">Hermann Brenner</name><affiliation><nlm:aff id="A25">Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Muller, Heiko" sort="Muller, Heiko" uniqKey="Muller H" first="Heiko" last="Müller">Heiko Müller</name><affiliation><nlm:aff id="A25">Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Arndt, Volker" sort="Arndt, Volker" uniqKey="Arndt V" first="Volker" last="Arndt">Volker Arndt</name><affiliation><nlm:aff id="A25">Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Stegmaier, Christa" sort="Stegmaier, Christa" uniqKey="Stegmaier C" first="Christa" last="Stegmaier">Christa Stegmaier</name><affiliation><nlm:aff id="A26">Saarland Cancer Registry, Saarbrücken, Germany</nlm:aff></affiliation></author><author><name sortKey="Miron, Penelope" sort="Miron, Penelope" uniqKey="Miron P" first="Penelope" last="Miron">Penelope Miron</name><affiliation><nlm:aff id="A27">Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, USA</nlm:aff></affiliation></author><author><name sortKey="Yannoukakos, Drakoulis" sort="Yannoukakos, Drakoulis" uniqKey="Yannoukakos D" first="Drakoulis" last="Yannoukakos">Drakoulis Yannoukakos</name><affiliation><nlm:aff id="A28">Molecular Diagnostics Laboratory, IRRP, National Centre for Scientific Research ‘Demokritos’, Athens, Greece</nlm:aff></affiliation></author><author><name sortKey="Stavropoulou, Alexandra" sort="Stavropoulou, Alexandra" uniqKey="Stavropoulou A" first="Alexandra" last="Stavropoulou">Alexandra Stavropoulou</name><affiliation><nlm:aff id="A28">Molecular Diagnostics Laboratory, IRRP, National Centre for Scientific Research ‘Demokritos’, Athens, Greece</nlm:aff></affiliation></author><author><name sortKey="Fountzilas, George" sort="Fountzilas, George" uniqKey="Fountzilas G" first="George" last="Fountzilas">George Fountzilas</name><affiliation><nlm:aff id="A29">Department of Medical Oncology, “Papageorgiou” Hospital, Ring Road, Aristotle University of Thessaloniki School of Medicine, Thessaloniki, Greece</nlm:aff></affiliation></author><author><name sortKey="Gogas, Helen J" sort="Gogas, Helen J" uniqKey="Gogas H" first="Helen J." last="Gogas">Helen J. Gogas</name><affiliation><nlm:aff id="A30">First Department of Medicine, University of Athens, Medical School, Athens, Greece</nlm:aff></affiliation></author><author><name sortKey="Swann, Ruth" sort="Swann, Ruth" uniqKey="Swann R" first="Ruth" last="Swann">Ruth Swann</name><affiliation><nlm:aff id="A31">Against Breast Cancer Research Unit, School of Life Sciences, University of Westminster, London, UK</nlm:aff></affiliation></author><author><name sortKey="Dwek, Miriam" sort="Dwek, Miriam" uniqKey="Dwek M" first="Miriam" last="Dwek">Miriam Dwek</name><affiliation><nlm:aff id="A31">Against Breast Cancer Research Unit, School of Life Sciences, University of Westminster, London, UK</nlm:aff></affiliation></author><author><name sortKey="Perkins, Annie" sort="Perkins, Annie" uniqKey="Perkins A" first="Annie" last="Perkins">Annie Perkins</name><affiliation><nlm:aff id="A31">Against Breast Cancer Research Unit, School of Life Sciences, University of Westminster, London, UK</nlm:aff></affiliation></author><author><name sortKey="Milne, Roger L" sort="Milne, Roger L" uniqKey="Milne R" first="Roger L." last="Milne">Roger L. Milne</name><affiliation><nlm:aff id="A32">Genetic & Molecular Epidemiology Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain</nlm:aff></affiliation></author><author><name sortKey="Benitez, Javier" sort="Benitez, Javier" uniqKey="Benitez J" first="Javier" last="Benítez">Javier Benítez</name><affiliation><nlm:aff id="A33">Human Genetics Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain</nlm:aff></affiliation></author><author><name sortKey="Zamora, M Pilar" sort="Zamora, M Pilar" uniqKey="Zamora M" first="M Pilar" last="Zamora">M Pilar Zamora</name><affiliation><nlm:aff id="A34">Servicio de Oncología Médica, Hospital Universitario La Paz, Madrid, Spain</nlm:aff></affiliation></author><author><name sortKey="Perez, Jose Ignacio Arias" sort="Perez, Jose Ignacio Arias" uniqKey="Perez J" first="José Ignacio Arias" last="Pérez">José Ignacio Arias Pérez</name><affiliation><nlm:aff id="A35">Servicio de Cirugía General y Especialidades, Hospital Monte Naranco, Oviedo, Spain</nlm:aff></affiliation></author><author><name sortKey="Bojesen, Stig E" sort="Bojesen, Stig E" uniqKey="Bojesen S" first="Stig E." last="Bojesen">Stig E. Bojesen</name><affiliation><nlm:aff id="A36">Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark</nlm:aff></affiliation><affiliation><nlm:aff id="A37">The Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark</nlm:aff></affiliation></author><author><name sortKey="Nielsen, Sune F" sort="Nielsen, Sune F" uniqKey="Nielsen S" first="Sune F." last="Nielsen">Sune F. Nielsen</name><affiliation><nlm:aff id="A36">Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark</nlm:aff></affiliation><affiliation><nlm:aff id="A37">The Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark</nlm:aff></affiliation></author><author><name sortKey="Nordestgaard, B Rge G" sort="Nordestgaard, B Rge G" uniqKey="Nordestgaard B" first="B Rge G" last="Nordestgaard">B Rge G. Nordestgaard</name><affiliation><nlm:aff id="A36">Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark</nlm:aff></affiliation><affiliation><nlm:aff id="A37">The Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark</nlm:aff></affiliation></author><author><name sortKey="Flyger, Henrik" sort="Flyger, Henrik" uniqKey="Flyger H" first="Henrik" last="Flyger">Henrik Flyger</name><affiliation><nlm:aff id="A38">Department of Breast Surgery, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark</nlm:aff></affiliation></author><author><name sortKey="Guenel, Pascal" sort="Guenel, Pascal" uniqKey="Guenel P" first="Pascal" last="Guénel">Pascal Guénel</name><affiliation><nlm:aff id="A39">Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer, Villejuif, France</nlm:aff></affiliation><affiliation><nlm:aff id="A40">University Paris-Sud, UMRS1018 Villejuif, France</nlm:aff></affiliation></author><author><name sortKey="Truong, Therese" sort="Truong, Therese" uniqKey="Truong T" first="Thérèse" last="Truong">Thérèse Truong</name><affiliation><nlm:aff id="A39">Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer, Villejuif, France</nlm:aff></affiliation><affiliation><nlm:aff id="A40">University Paris-Sud, UMRS1018 Villejuif, France</nlm:aff></affiliation></author><author><name sortKey="Menegaux, Florence" sort="Menegaux, Florence" uniqKey="Menegaux F" first="Florence" last="Menegaux">Florence Menegaux</name><affiliation><nlm:aff id="A39">Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer, Villejuif, France</nlm:aff></affiliation><affiliation><nlm:aff id="A40">University Paris-Sud, UMRS1018 Villejuif, France</nlm:aff></affiliation></author><author><name sortKey="Cordina Duverger, Emilie" sort="Cordina Duverger, Emilie" uniqKey="Cordina Duverger E" first="Emilie" last="Cordina-Duverger">Emilie Cordina-Duverger</name><affiliation><nlm:aff id="A39">Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer, Villejuif, France</nlm:aff></affiliation><affiliation><nlm:aff id="A40">University Paris-Sud, UMRS1018 Villejuif, France</nlm:aff></affiliation></author><author><name sortKey="Burwinkel, Barbara" sort="Burwinkel, Barbara" uniqKey="Burwinkel B" first="Barbara" last="Burwinkel">Barbara Burwinkel</name><affiliation><nlm:aff id="A20">Department of Obstetrics and Gynecology, University Hospital Heidelberg, Heidelberg, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A41">Molecular Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Marme, Frederick" sort="Marme, Frederick" uniqKey="Marme F" first="Frederick" last="Marmé">Frederick Marmé</name><affiliation><nlm:aff id="A20">Department of Obstetrics and Gynecology, University Hospital Heidelberg, Heidelberg, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A42">National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Schneeweiss, Andreas" sort="Schneeweiss, Andreas" uniqKey="Schneeweiss A" first="Andreas" last="Schneeweiss">Andreas Schneeweiss</name><affiliation><nlm:aff id="A20">Department of Obstetrics and Gynecology, University Hospital Heidelberg, Heidelberg, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A42">National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Sohn, Christof" sort="Sohn, Christof" uniqKey="Sohn C" first="Christof" last="Sohn">Christof Sohn</name><affiliation><nlm:aff id="A20">Department of Obstetrics and Gynecology, University Hospital Heidelberg, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Sawyer, Elinor" sort="Sawyer, Elinor" uniqKey="Sawyer E" first="Elinor" last="Sawyer">Elinor Sawyer</name><affiliation><nlm:aff id="A43">National Institute for Health Research (NIHR) Comprehensive Biomedical Research Centre, Guy’s & St. Thomas’ NHS Foundation Trust in partnership with King’s College London and King’s College Hospital NHS Foundation Trus, London, UK</nlm:aff></affiliation></author><author><name sortKey="Tomlinson, Ian" sort="Tomlinson, Ian" uniqKey="Tomlinson I" first="Ian" last="Tomlinson">Ian Tomlinson</name><affiliation><nlm:aff id="A44">Welcome Trust Centre for Human Genetics and Oxford Biomedical Research Centre, University of Oxford, Oxford, UK</nlm:aff></affiliation></author><author><name sortKey="Kerin, Michael J" sort="Kerin, Michael J" uniqKey="Kerin M" first="Michael J." last="Kerin">Michael J. Kerin</name><affiliation><nlm:aff id="A45">NUIG Department of Surgery, Clinical Science Institute, University Hospital Galway, Galway, Ireland</nlm:aff></affiliation></author><author><name sortKey="Peto, Julian" sort="Peto, Julian" uniqKey="Peto J" first="Julian" last="Peto">Julian Peto</name><affiliation><nlm:aff id="A46">Department of Nion-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK</nlm:aff></affiliation></author><author><name sortKey="Johnson, Nichola" sort="Johnson, Nichola" uniqKey="Johnson N" first="Nichola" last="Johnson">Nichola Johnson</name><affiliation><nlm:aff id="A47">Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK</nlm:aff></affiliation></author><author><name sortKey="Fletcher, Olivia" sort="Fletcher, Olivia" uniqKey="Fletcher O" first="Olivia" last="Fletcher">Olivia Fletcher</name><affiliation><nlm:aff id="A47">Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK</nlm:aff></affiliation></author><author><name sortKey="Silva, Isabel Dos Santos" sort="Silva, Isabel Dos Santos" uniqKey="Silva I" first="Isabel Dos Santos" last="Silva">Isabel Dos Santos Silva</name><affiliation><nlm:aff id="A48">Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK</nlm:aff></affiliation></author><author><name sortKey="Fasching, Peter A" sort="Fasching, Peter A" uniqKey="Fasching P" first="Peter A." last="Fasching">Peter A. Fasching</name><affiliation><nlm:aff id="A49">University of California at Los Angeles, David Geffen School of Medicine, Department of Medicine, Division of Hematology and Oncology, Los Angeles, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A50">University Breast Center Franconia, Department of Gynecology and Obstetrics, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center, Erlangen-Nuremberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Beckmann, Matthias W" sort="Beckmann, Matthias W" uniqKey="Beckmann M" first="Matthias W." last="Beckmann">Matthias W. Beckmann</name><affiliation><nlm:aff id="A50">University Breast Center Franconia, Department of Gynecology and Obstetrics, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center, Erlangen-Nuremberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Hartmann, Arndt" sort="Hartmann, Arndt" uniqKey="Hartmann A" first="Arndt" last="Hartmann">Arndt Hartmann</name><affiliation><nlm:aff id="A51">Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen-Nuremberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Ekici, Arif B" sort="Ekici, Arif B" uniqKey="Ekici A" first="Arif B." last="Ekici">Arif B. Ekici</name><affiliation><nlm:aff id="A52">Institute of Human Genetics, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen-Nuremberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Lophatananon, Artitaya" sort="Lophatananon, Artitaya" uniqKey="Lophatananon A" first="Artitaya" last="Lophatananon">Artitaya Lophatananon</name><affiliation><nlm:aff id="A53">Health Sciences Research Institute, Warwick Medical School, Warwick University, Coventry, UK</nlm:aff></affiliation></author><author><name sortKey="Muir, Kenneth" sort="Muir, Kenneth" uniqKey="Muir K" first="Kenneth" last="Muir">Kenneth Muir</name><affiliation><nlm:aff id="A53">Health Sciences Research Institute, Warwick Medical School, Warwick University, Coventry, UK</nlm:aff></affiliation></author><author><name sortKey="Puttawibul, Puttisak" sort="Puttawibul, Puttisak" uniqKey="Puttawibul P" first="Puttisak" last="Puttawibul">Puttisak Puttawibul</name><affiliation><nlm:aff id="A54">Department of Surgery, Medical school, Prince Songkla University, Songkla, Thailand</nlm:aff></affiliation></author><author><name sortKey="Wiangnon, Surapon" sort="Wiangnon, Surapon" uniqKey="Wiangnon S" first="Surapon" last="Wiangnon">Surapon Wiangnon</name><affiliation><nlm:aff id="A55">Department of Pediatrics, Medical school, Khon Kaen University, Khon Kaen, Thailand</nlm:aff></affiliation></author><author><name sortKey="Schmidt, Marjanka K" sort="Schmidt, Marjanka K" uniqKey="Schmidt M" first="Marjanka K" last="Schmidt">Marjanka K. Schmidt</name><affiliation><nlm:aff id="A56">Netherlands Cancer Institute, Amsterdam, Netherlands</nlm:aff></affiliation></author><author><name sortKey="Broeks, Annegien" sort="Broeks, Annegien" uniqKey="Broeks A" first="Annegien" last="Broeks">Annegien Broeks</name><affiliation><nlm:aff id="A56">Netherlands Cancer Institute, Amsterdam, Netherlands</nlm:aff></affiliation></author><author><name sortKey="Braaf, Linde M" sort="Braaf, Linde M" uniqKey="Braaf L" first="Linde M" last="Braaf">Linde M. Braaf</name><affiliation><nlm:aff id="A56">Netherlands Cancer Institute, Amsterdam, Netherlands</nlm:aff></affiliation></author><author><name sortKey="Rosenberg, Efraim H" sort="Rosenberg, Efraim H" uniqKey="Rosenberg E" first="Efraim H" last="Rosenberg">Efraim H. Rosenberg</name><affiliation><nlm:aff id="A56">Netherlands Cancer Institute, Amsterdam, Netherlands</nlm:aff></affiliation></author><author><name sortKey="Hopper, John L" sort="Hopper, John L" uniqKey="Hopper J" first="John L." last="Hopper">John L. Hopper</name><affiliation><nlm:aff id="A57">Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia</nlm:aff></affiliation></author><author><name sortKey="Apicella, Carmel" sort="Apicella, Carmel" uniqKey="Apicella C" first="Carmel" last="Apicella">Carmel Apicella</name><affiliation><nlm:aff id="A57">Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia</nlm:aff></affiliation></author><author><name sortKey="Park, Daniel J" sort="Park, Daniel J" uniqKey="Park D" first="Daniel J." last="Park">Daniel J. Park</name><affiliation><nlm:aff id="A58">Department of Pathology, The University of Melbourne, Melbourne, Australia</nlm:aff></affiliation></author><author><name sortKey="Southey, Melissa C" sort="Southey, Melissa C" uniqKey="Southey M" first="Melissa C." last="Southey">Melissa C. Southey</name><affiliation><nlm:aff id="A58">Department of Pathology, The University of Melbourne, Melbourne, Australia</nlm:aff></affiliation></author><author><name sortKey="Swerdlow, Anthony J" sort="Swerdlow, Anthony J" uniqKey="Swerdlow A" first="Anthony J." last="Swerdlow">Anthony J. Swerdlow</name><affiliation><nlm:aff id="A59">Section of Epidemiology, Institute of Cancer Research., Sutton,, UK</nlm:aff></affiliation></author><author><name sortKey="Ashworth, Alan" sort="Ashworth, Alan" uniqKey="Ashworth A" first="Alan" last="Ashworth">Alan Ashworth</name><affiliation><nlm:aff id="A60">The Breakthrough Breast Cancer Research Centre, Institute of Cancer Research., London, UK</nlm:aff></affiliation></author><author><name sortKey="Orr, Nicholas" sort="Orr, Nicholas" uniqKey="Orr N" first="Nicholas" last="Orr">Nicholas Orr</name><affiliation><nlm:aff id="A60">The Breakthrough Breast Cancer Research Centre, Institute of Cancer Research., London, UK</nlm:aff></affiliation></author><author><name sortKey="Schoemaker, Minouk J" sort="Schoemaker, Minouk J" uniqKey="Schoemaker M" first="Minouk J." last="Schoemaker">Minouk J. Schoemaker</name><affiliation><nlm:aff id="A59">Section of Epidemiology, Institute of Cancer Research., Sutton,, UK</nlm:aff></affiliation></author><author><name sortKey="Anton Culver, Hoda" sort="Anton Culver, Hoda" uniqKey="Anton Culver H" first="Hoda" last="Anton-Culver">Hoda Anton-Culver</name><affiliation><nlm:aff id="A61">Department of Epidemiology, School of Medicine, University of California Irvine, Irvine, CA</nlm:aff></affiliation></author><author><name sortKey="Ziogas, Argyrios" sort="Ziogas, Argyrios" uniqKey="Ziogas A" first="Argyrios" last="Ziogas">Argyrios Ziogas</name><affiliation><nlm:aff id="A61">Department of Epidemiology, School of Medicine, University of California Irvine, Irvine, CA</nlm:aff></affiliation></author><author><name sortKey="Bernstein, Leslie" sort="Bernstein, Leslie" uniqKey="Bernstein L" first="Leslie" last="Bernstein">Leslie Bernstein</name><affiliation><nlm:aff id="A62">Division of Cancer Etiology, Department of Population Sciences, Beckman Research Institute, City of Hope</nlm:aff></affiliation></author><author><name sortKey="Dur, Christina Clarke" sort="Dur, Christina Clarke" uniqKey="Dur C" first="Christina Clarke" last="Dur">Christina Clarke Dur</name><affiliation><nlm:aff id="A63">Department of Epidemiology, Cancer Prevention Institute of California, Fremont, CA</nlm:aff></affiliation></author><author><name sortKey="Shen, Chen Yang" sort="Shen, Chen Yang" uniqKey="Shen C" first="Chen-Yang" last="Shen">Chen-Yang Shen</name><affiliation><nlm:aff id="A64">Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan</nlm:aff></affiliation></author><author><name sortKey="Yu, Jyh Cherng" sort="Yu, Jyh Cherng" uniqKey="Yu J" first="Jyh-Cherng" last="Yu">Jyh-Cherng Yu</name><affiliation><nlm:aff id="A65">Department of Surgery, Tri-Service General Hospital, Taipei, Taiwan</nlm:aff></affiliation></author><author><name sortKey="Hsu, Huan Ming" sort="Hsu, Huan Ming" uniqKey="Hsu H" first="Huan-Ming" last="Hsu">Huan-Ming Hsu</name><affiliation><nlm:aff id="A65">Department of Surgery, Tri-Service General Hospital, Taipei, Taiwan</nlm:aff></affiliation></author><author><name sortKey="Hsiung, Chia Ni" sort="Hsiung, Chia Ni" uniqKey="Hsiung C" first="Chia-Ni" last="Hsiung">Chia-Ni Hsiung</name><affiliation><nlm:aff id="A64">Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan</nlm:aff></affiliation></author><author><name sortKey="Hamann, Ute" sort="Hamann, Ute" uniqKey="Hamann U" first="Ute" last="Hamann">Ute Hamann</name><affiliation><nlm:aff id="A66">Molecular Genetics of Breast Cancer, Deutsches Krebsforschungsfzentrum (DKFZ), Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Dunnebier, Thomas" sort="Dunnebier, Thomas" uniqKey="Dunnebier T" first="Thomas" last="Dünnebier">Thomas Dünnebier</name><affiliation><nlm:aff id="A66">Molecular Genetics of Breast Cancer, Deutsches Krebsforschungsfzentrum (DKFZ), Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Rudiger, Thomas" sort="Rudiger, Thomas" uniqKey="Rudiger T" first="Thomas" last="Rüdiger">Thomas Rüdiger</name><affiliation><nlm:aff id="A67">Institute of Pathology, Städtisches Klinikum Karlsruhe, Karlsruhe, Germany</nlm:aff></affiliation></author><author><name sortKey="Ulmer, Hans Ulrich" sort="Ulmer, Hans Ulrich" uniqKey="Ulmer H" first="Hans Ulrich" last="Ulmer">Hans Ulrich Ulmer</name><affiliation><nlm:aff id="A68">Women’s Clinic, Städtisches Klinikum Karlsruhe, Karlsruhe, Germany</nlm:aff></affiliation></author><author><name sortKey="Pharoah, Paul P" sort="Pharoah, Paul P" uniqKey="Pharoah P" first="Paul P." last="Pharoah">Paul P. Pharoah</name><affiliation><nlm:aff id="A69">Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK</nlm:aff></affiliation><affiliation><nlm:aff id="A70">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Dunning, Alison M" sort="Dunning, Alison M" uniqKey="Dunning A" first="Alison M" last="Dunning">Alison M. Dunning</name><affiliation><nlm:aff id="A69">Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Humphreys, Manjeet K" sort="Humphreys, Manjeet K" uniqKey="Humphreys M" first="Manjeet K." last="Humphreys">Manjeet K. Humphreys</name><affiliation><nlm:aff id="A70">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Wang, Qin" sort="Wang, Qin" uniqKey="Wang Q" first="Qin" last="Wang">Qin Wang</name><affiliation><nlm:aff id="A70">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Cox, Angela" sort="Cox, Angela" uniqKey="Cox A" first="Angela" last="Cox">Angela Cox</name><affiliation><nlm:aff id="A71">Dept of Oncology, Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, UK</nlm:aff></affiliation></author><author><name sortKey="Cross, Simon S" sort="Cross, Simon S" uniqKey="Cross S" first="Simon S." last="Cross">Simon S. Cross</name><affiliation><nlm:aff id="A72">Department of Neuroscience, Faculty of Medicine, Dentistry & Health, University of Sheffield, Sheffield, UK</nlm:aff></affiliation></author><author><name sortKey="Reed, Malcom W" sort="Reed, Malcom W" uniqKey="Reed M" first="Malcom W." last="Reed">Malcom W. Reed</name><affiliation><nlm:aff id="A71">Dept of Oncology, Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, UK</nlm:aff></affiliation></author><author><name sortKey="Hall, Per" sort="Hall, Per" uniqKey="Hall P" first="Per" last="Hall">Per Hall</name><affiliation><nlm:aff id="A73">Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</nlm:aff></affiliation></author><author><name sortKey="Czene, Kamila" sort="Czene, Kamila" uniqKey="Czene K" first="Kamila" last="Czene">Kamila Czene</name><affiliation><nlm:aff id="A73">Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</nlm:aff></affiliation></author><author><name sortKey="Ambrosone, Christine B" sort="Ambrosone, Christine B" uniqKey="Ambrosone C" first="Christine B." last="Ambrosone">Christine B. Ambrosone</name><affiliation><nlm:aff id="A74">Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, USA</nlm:aff></affiliation></author><author><name sortKey="Ademuyiwa, Foluso" sort="Ademuyiwa, Foluso" uniqKey="Ademuyiwa F" first="Foluso" last="Ademuyiwa">Foluso Ademuyiwa</name><affiliation><nlm:aff id="A75">Department of Medicine, Roswell Park Cancer Institute, Buffalo, USA</nlm:aff></affiliation></author><author><name sortKey="Hwang, Helena" sort="Hwang, Helena" uniqKey="Hwang H" first="Helena" last="Hwang">Helena Hwang</name><affiliation><nlm:aff id="A76">Department of Pathology, Roswell Park Cancer Institute, Buffalo, USA</nlm:aff></affiliation></author><author><name sortKey="Eccles, Diana M" sort="Eccles, Diana M" uniqKey="Eccles D" first="Diana M." last="Eccles">Diana M. Eccles</name><affiliation><nlm:aff id="A77">Faculty of Medicine, University of Southampton, Southampton, UK</nlm:aff></affiliation></author><author><name sortKey="Garcia Closas, Montserrat" sort="Garcia Closas, Montserrat" uniqKey="Garcia Closas M" first="Montserrat" last="Garcia-Closas">Montserrat Garcia-Closas</name><affiliation><nlm:aff id="A78">Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, UK</nlm:aff></affiliation></author><author><name sortKey="Figueroa, Jonine D" sort="Figueroa, Jonine D" uniqKey="Figueroa J" first="Jonine D." last="Figueroa">Jonine D. Figueroa</name><affiliation><nlm:aff id="A79">Division of Cancer Epidemiology and Genetics, Hormonal and Reproductive Epidemiology Branch, NIH/NCI, Bethesda, USA</nlm:aff></affiliation></author><author><name sortKey="Sherman, Mark E" sort="Sherman, Mark E" uniqKey="Sherman M" first="Mark E." last="Sherman">Mark E. Sherman</name><affiliation><nlm:aff id="A79">Division of Cancer Epidemiology and Genetics, Hormonal and Reproductive Epidemiology Branch, NIH/NCI, Bethesda, USA</nlm:aff></affiliation></author><author><name sortKey="Lissowska, Jolanta" sort="Lissowska, Jolanta" uniqKey="Lissowska J" first="Jolanta" last="Lissowska">Jolanta Lissowska</name><affiliation><nlm:aff id="A80">Department of Cancer Epidemiology and Prevention, The M. Sklodowska-Curie Cancer Center and Institute of Oncology, Warsaw, Poland</nlm:aff></affiliation></author><author><name sortKey="Devilee, Peter" sort="Devilee, Peter" uniqKey="Devilee P" first="Peter" last="Devilee">Peter Devilee</name><affiliation><nlm:aff id="A81">Department of Human Genetics & Department of Pathology, Leiden University Medical Center, Leiden, Netherlands</nlm:aff></affiliation></author><author><name sortKey="Seynaeve, Caroline" sort="Seynaeve, Caroline" uniqKey="Seynaeve C" first="Caroline" last="Seynaeve">Caroline Seynaeve</name><affiliation><nlm:aff id="A82">Department of Medical Oncology, Erasmus Medical Center, Daniel den Hoed Cancer Center, Rotterdam, Netherlands</nlm:aff></affiliation></author><author><name sortKey="Tollenaar, R A E M" sort="Tollenaar, R A E M" uniqKey="Tollenaar R" first="R. A. E. M." last="Tollenaar">R. A. E. M. Tollenaar</name><affiliation><nlm:aff id="A83">Department of Surgical Oncology, Leiden University Medical Center, Leiden, Netherlands</nlm:aff></affiliation></author><author><name sortKey="Hooning, Maartje J" sort="Hooning, Maartje J" uniqKey="Hooning M" first="Maartje J." last="Hooning">Maartje J. Hooning</name><affiliation><nlm:aff id="A82">Department of Medical Oncology, Erasmus Medical Center, Daniel den Hoed Cancer Center, Rotterdam, Netherlands</nlm:aff></affiliation></author><author><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L." last="Andrulis">Irene L. Andrulis</name><affiliation><nlm:aff id="A84">Departments of Molecular Genetics and Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada</nlm:aff></affiliation></author><author><name sortKey="Knight, Julia A" sort="Knight, Julia A" uniqKey="Knight J" first="Julia A." last="Knight">Julia A. Knight</name><affiliation><nlm:aff id="A85">Dalla Lana School of Public Health, University of Toronto, Prosserman Centre for Health Research, Toronto, Canada</nlm:aff></affiliation></author><author><name sortKey="Glendon, Gord" sort="Glendon, Gord" uniqKey="Glendon G" first="Gord" last="Glendon">Gord Glendon</name><affiliation><nlm:aff id="A86">Cancer Care Ontario, Princess Margaret Hospital, Toronto, Canada</nlm:aff></affiliation></author><author><name sortKey="Mulligan, Anna Marie" sort="Mulligan, Anna Marie" uniqKey="Mulligan A" first="Anna Marie" last="Mulligan">Anna Marie Mulligan</name><affiliation><nlm:aff id="A87">Department of Laboratory Medicine, Keenan Research Centre of the Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, Canada</nlm:aff></affiliation></author><author><name sortKey="Winqvist, Robert" sort="Winqvist, Robert" uniqKey="Winqvist R" first="Robert" last="Winqvist">Robert Winqvist</name><affiliation><nlm:aff id="A88">Department of Clinical Genetics, Institute of Clinical Medicine, Biocenter Oulu, University of Oulu, Oulu University Hospital, Oulu, Finland</nlm:aff></affiliation></author><author><name sortKey="Pylk S, Katri" sort="Pylk S, Katri" uniqKey="Pylk S K" first="Katri" last="Pylk S">Katri Pylk S</name><affiliation><nlm:aff id="A88">Department of Clinical Genetics, Institute of Clinical Medicine, Biocenter Oulu, University of Oulu, Oulu University Hospital, Oulu, Finland</nlm:aff></affiliation></author><author><name sortKey="Jukkola Vuorinen, Arja" sort="Jukkola Vuorinen, Arja" uniqKey="Jukkola Vuorinen A" first="Arja" last="Jukkola-Vuorinen">Arja Jukkola-Vuorinen</name><affiliation><nlm:aff id="A89">Department of Oncology, University of Oulu, Oulu University Hospital, Oulu, Finland</nlm:aff></affiliation></author><author><name sortKey="Grip, Mervi" sort="Grip, Mervi" uniqKey="Grip M" first="Mervi" last="Grip">Mervi Grip</name><affiliation><nlm:aff id="A90">Department of Surgery, University of Oulu, Oulu University Hospital, Oulu, Finland</nlm:aff></affiliation></author><author><name sortKey="John, Esther M" sort="John, Esther M" uniqKey="John E" first="Esther M." last="John">Esther M. John</name><affiliation><nlm:aff id="A63">Department of Epidemiology, Cancer Prevention Institute of California, Fremont, CA</nlm:aff></affiliation></author><author><name sortKey="Miron, Alexander" sort="Miron, Alexander" uniqKey="Miron A" first="Alexander" last="Miron">Alexander Miron</name><affiliation><nlm:aff id="A27">Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, USA</nlm:aff></affiliation></author><author><name sortKey="Aln S, Grethe Grenaker" sort="Aln S, Grethe Grenaker" uniqKey="Aln S G" first="Grethe Grenaker" last="Aln S">Grethe Grenaker Aln S</name><affiliation><nlm:aff id="A91">Institute for Clinical Epidemiology and Molecular Biology (EpiGen), Faculty of Medicine, University of Oslo, Oslo, Norway</nlm:aff></affiliation><affiliation><nlm:aff id="A92">Group of Cancer Genome Variation Department of Genetics, Institute for Cancer Research, Oslo, Norway</nlm:aff></affiliation></author><author><name sortKey="Kristensen, Vessela" sort="Kristensen, Vessela" uniqKey="Kristensen V" first="Vessela" last="Kristensen">Vessela Kristensen</name><affiliation><nlm:aff id="A91">Institute for Clinical Epidemiology and Molecular Biology (EpiGen), Faculty of Medicine, University of Oslo, Oslo, Norway</nlm:aff></affiliation><affiliation><nlm:aff id="A92">Group of Cancer Genome Variation Department of Genetics, Institute for Cancer Research, Oslo, Norway</nlm:aff></affiliation></author><author><name sortKey="B Rresen Dale, Anne Lise" sort="B Rresen Dale, Anne Lise" uniqKey="B Rresen Dale A" first="Anne-Lise" last="B Rresen-Dale">Anne-Lise B Rresen-Dale</name><affiliation><nlm:aff id="A93">Department of Genetics, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo, Norway</nlm:aff></affiliation></author><author><name sortKey="Giles, Graham G" sort="Giles, Graham G" uniqKey="Giles G" first="Graham G." last="Giles">Graham G. Giles</name><affiliation><nlm:aff id="A94">Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Australia</nlm:aff></affiliation><affiliation><nlm:aff id="A95">Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia</nlm:aff></affiliation></author><author><name sortKey="Baglietto, Laura" sort="Baglietto, Laura" uniqKey="Baglietto L" first="Laura" last="Baglietto">Laura Baglietto</name><affiliation><nlm:aff id="A94">Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Australia</nlm:aff></affiliation><affiliation><nlm:aff id="A95">Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia</nlm:aff></affiliation></author><author><name sortKey="Mclean, Catriona A" sort="Mclean, Catriona A" uniqKey="Mclean C" first="Catriona A" last="Mclean">Catriona A. Mclean</name><affiliation><nlm:aff id="A96">The Alfred Hospital, Melbourne, Australia</nlm:aff></affiliation></author><author><name sortKey="Severi, Gianluca" sort="Severi, Gianluca" uniqKey="Severi G" first="Gianluca" last="Severi">Gianluca Severi</name><affiliation><nlm:aff id="A94">Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Australia</nlm:aff></affiliation><affiliation><nlm:aff id="A95">Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia</nlm:aff></affiliation></author><author><name sortKey="Kosel, Matthew L" sort="Kosel, Matthew L" uniqKey="Kosel M" first="Matthew L." last="Kosel">Matthew L. Kosel</name><affiliation><nlm:aff id="A1">Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota</nlm:aff></affiliation></author><author><name sortKey="Pankratz, V S" sort="Pankratz, V S" uniqKey="Pankratz V" first="V. S." last="Pankratz">V. S. Pankratz</name><affiliation><nlm:aff id="A1">Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota</nlm:aff></affiliation></author><author><name sortKey="Slager, Susan" sort="Slager, Susan" uniqKey="Slager S" first="Susan" last="Slager">Susan Slager</name><affiliation><nlm:aff id="A1">Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota</nlm:aff></affiliation></author><author><name sortKey="Olson, Janet E" sort="Olson, Janet E" uniqKey="Olson J" first="Janet E." last="Olson">Janet E. Olson</name><affiliation><nlm:aff id="A1">Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota</nlm:aff></affiliation></author><author><name sortKey="Radice, Paolo" sort="Radice, Paolo" uniqKey="Radice P" first="Paolo" last="Radice">Paolo Radice</name><affiliation><nlm:aff id="A97">Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale, Tumori (INT), Milan, Italy</nlm:aff></affiliation><affiliation><nlm:aff id="A98">IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy</nlm:aff></affiliation></author><author><name sortKey="Peterlongo, Paolo" sort="Peterlongo, Paolo" uniqKey="Peterlongo P" first="Paolo" last="Peterlongo">Paolo Peterlongo</name><affiliation><nlm:aff id="A97">Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale, Tumori (INT), Milan, Italy</nlm:aff></affiliation><affiliation><nlm:aff id="A98">IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy</nlm:aff></affiliation></author><author><name sortKey="Manoukian, Siranoush" sort="Manoukian, Siranoush" uniqKey="Manoukian S" first="Siranoush" last="Manoukian">Siranoush Manoukian</name><affiliation><nlm:aff id="A99">Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy</nlm:aff></affiliation></author><author><name sortKey="Barile, Monica" sort="Barile, Monica" uniqKey="Barile M" first="Monica" last="Barile">Monica Barile</name><affiliation><nlm:aff id="A100">Division of Cancer Prevention and Genetics, Chemoprevention, European Institute of Oncology, Milan, Italy</nlm:aff></affiliation></author><author><name sortKey="Lambrechts, Diether" sort="Lambrechts, Diether" uniqKey="Lambrechts D" first="Diether" last="Lambrechts">Diether Lambrechts</name><affiliation><nlm:aff id="A101">Vesalius Research Center, VIB, Leuven, Belgium</nlm:aff></affiliation><affiliation><nlm:aff id="A102">Vesalius Research Center, University of Leuven, Leuven, Belgium</nlm:aff></affiliation></author><author><name sortKey="Hatse, Sigrid" sort="Hatse, Sigrid" uniqKey="Hatse S" first="Sigrid" last="Hatse">Sigrid Hatse</name><affiliation><nlm:aff id="A103">Multidisciplinary Breast Center, University Hospital Gasthuisberg, Leuven, Belgium</nlm:aff></affiliation></author><author><name sortKey="Dieudonne, Anne Sophie" sort="Dieudonne, Anne Sophie" uniqKey="Dieudonne A" first="Anne-Sophie" last="Dieudonne">Anne-Sophie Dieudonne</name><affiliation><nlm:aff id="A103">Multidisciplinary Breast Center, University Hospital Gasthuisberg, Leuven, Belgium</nlm:aff></affiliation></author><author><name sortKey="Christiaens, Marie Rose" sort="Christiaens, Marie Rose" uniqKey="Christiaens M" first="Marie-Rose" last="Christiaens">Marie-Rose Christiaens</name><affiliation><nlm:aff id="A103">Multidisciplinary Breast Center, University Hospital Gasthuisberg, Leuven, Belgium</nlm:aff></affiliation></author><author><name sortKey="Chenevix Trench, Georgia" sort="Chenevix Trench, Georgia" uniqKey="Chenevix Trench G" first="Georgia" last="Chenevix-Trench">Georgia Chenevix-Trench</name><affiliation><nlm:aff id="A104">Queensland Institute of Medical Research, Herston, Australia</nlm:aff></affiliation></author><author><name sortKey="Beesley, Jonathan" sort="Beesley, Jonathan" uniqKey="Beesley J" first="Jonathan" last="Beesley">Jonathan Beesley</name><affiliation><nlm:aff id="A104">Queensland Institute of Medical Research, Herston, Australia</nlm:aff></affiliation></author><author><name sortKey="Chen, Xiaoqing" sort="Chen, Xiaoqing" uniqKey="Chen X" first="Xiaoqing" last="Chen">Xiaoqing Chen</name><affiliation><nlm:aff id="A104">Queensland Institute of Medical Research, Herston, Australia</nlm:aff></affiliation></author><author><name sortKey="Mannermaa, Arto" sort="Mannermaa, Arto" uniqKey="Mannermaa A" first="Arto" last="Mannermaa">Arto Mannermaa</name><affiliation><nlm:aff id="A106">Institute of Clinical Medicine, Department of Pathology, University of Eastern Finland and Kuopio University Hospital, Biocenter Kuopio, Kuopio, Finland</nlm:aff></affiliation></author><author><name sortKey="Kosma, Veli Matti" sort="Kosma, Veli Matti" uniqKey="Kosma V" first="Veli-Matti" last="Kosma">Veli-Matti Kosma</name><affiliation><nlm:aff id="A106">Institute of Clinical Medicine, Department of Pathology, University of Eastern Finland and Kuopio University Hospital, Biocenter Kuopio, Kuopio, Finland</nlm:aff></affiliation></author><author><name sortKey="Hartikainen, Jaana M" sort="Hartikainen, Jaana M" uniqKey="Hartikainen J" first="Jaana M." last="Hartikainen">Jaana M. Hartikainen</name><affiliation><nlm:aff id="A106">Institute of Clinical Medicine, Department of Pathology, University of Eastern Finland and Kuopio University Hospital, Biocenter Kuopio, Kuopio, Finland</nlm:aff></affiliation></author><author><name sortKey="Soini, Ylermi" sort="Soini, Ylermi" uniqKey="Soini Y" first="Ylermi" last="Soini">Ylermi Soini</name><affiliation><nlm:aff id="A106">Institute of Clinical Medicine, Department of Pathology, University of Eastern Finland and Kuopio University Hospital, Biocenter Kuopio, Kuopio, Finland</nlm:aff></affiliation></author><author><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F." last="Easton">Douglas F. Easton</name><affiliation><nlm:aff id="A68">Women’s Clinic, Städtisches Klinikum Karlsruhe, Karlsruhe, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A69">Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Couch, Fergus J" sort="Couch, Fergus J" uniqKey="Couch F" first="Fergus J." last="Couch">Fergus J. Couch</name><affiliation><nlm:aff id="A2">Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">22331459</idno><idno type="pmc">3319792</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319792</idno><idno type="RBID">PMC:3319792</idno><idno type="doi">10.1158/0008-5472.CAN-11-3364</idno><date when="2012">2012</date><idno type="wicri:Area/Pmc/Corpus">001542</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001542</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">19p13.1 is a triple negative-specific breast cancer susceptibility locus</title><author><name sortKey="Stevens, Kristen N" sort="Stevens, Kristen N" uniqKey="Stevens K" first="Kristen N." last="Stevens">Kristen N. Stevens</name><affiliation><nlm:aff id="A1">Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota</nlm:aff></affiliation></author><author><name sortKey="Fredericksen, Zachary" sort="Fredericksen, Zachary" uniqKey="Fredericksen Z" first="Zachary" last="Fredericksen">Zachary Fredericksen</name><affiliation><nlm:aff id="A1">Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota</nlm:aff></affiliation></author><author><name sortKey="Vachon, Celine M" sort="Vachon, Celine M" uniqKey="Vachon C" first="Celine M." last="Vachon">Celine M. Vachon</name><affiliation><nlm:aff id="A1">Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota</nlm:aff></affiliation></author><author><name sortKey="Wang, Xianshu" sort="Wang, Xianshu" uniqKey="Wang X" first="Xianshu" last="Wang">Xianshu Wang</name><affiliation><nlm:aff id="A2">Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota</nlm:aff></affiliation></author><author><name sortKey="Margolin, Sara" sort="Margolin, Sara" uniqKey="Margolin S" first="Sara" last="Margolin">Sara Margolin</name><affiliation><nlm:aff id="A3">Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden</nlm:aff></affiliation></author><author><name sortKey="Lindblom, Annika" sort="Lindblom, Annika" uniqKey="Lindblom A" first="Annika" last="Lindblom">Annika Lindblom</name><affiliation><nlm:aff id="A3">Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden</nlm:aff></affiliation></author><author><name sortKey="Nevanlinna, Heli" sort="Nevanlinna, Heli" uniqKey="Nevanlinna H" first="Heli" last="Nevanlinna">Heli Nevanlinna</name><affiliation><nlm:aff id="A4">Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Biomedicum Helsinki, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Greco, Dario" sort="Greco, Dario" uniqKey="Greco D" first="Dario" last="Greco">Dario Greco</name><affiliation><nlm:aff id="A4">Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Biomedicum Helsinki, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Aittom Ki, Kristiina" sort="Aittom Ki, Kristiina" uniqKey="Aittom Ki K" first="Kristiina" last="Aittom Ki">Kristiina Aittom Ki</name><affiliation><nlm:aff id="A5">Department of Clinical Genetics, Helsinki University Central Hospital, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Blomqvist, Carl" sort="Blomqvist, Carl" uniqKey="Blomqvist C" first="Carl" last="Blomqvist">Carl Blomqvist</name><affiliation><nlm:aff id="A6">Department of Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Chang Claude, Jenny" sort="Chang Claude, Jenny" uniqKey="Chang Claude J" first="Jenny" last="Chang-Claude">Jenny Chang-Claude</name><affiliation><nlm:aff id="A7">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Vrieling, Alina" sort="Vrieling, Alina" uniqKey="Vrieling A" first="Alina" last="Vrieling">Alina Vrieling</name><affiliation><nlm:aff id="A7">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Flesch Janys, Dieter" sort="Flesch Janys, Dieter" uniqKey="Flesch Janys D" first="Dieter" last="Flesch-Janys">Dieter Flesch-Janys</name><affiliation><nlm:aff id="A8">Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg, Germany</nlm:aff></affiliation></author><author><name sortKey="Sinn, Hans Peter" sort="Sinn, Hans Peter" uniqKey="Sinn H" first="Hans-Peter" last="Sinn">Hans-Peter Sinn</name><affiliation><nlm:aff id="A9">Department of Pathology, University Hospital Heidelberg, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Wang Gohrke, Shan" sort="Wang Gohrke, Shan" uniqKey="Wang Gohrke S" first="Shan" last="Wang-Gohrke">Shan Wang-Gohrke</name><affiliation><nlm:aff id="A10">Department of Obstetrics and Gynecology, University of Ulm, Ulm, Germany</nlm:aff></affiliation></author><author><name sortKey="Nickels, Stefan" sort="Nickels, Stefan" uniqKey="Nickels S" first="Stefan" last="Nickels">Stefan Nickels</name><affiliation><nlm:aff id="A7">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Brauch, Hiltrud" sort="Brauch, Hiltrud" uniqKey="Brauch H" first="Hiltrud" last="Brauch">Hiltrud Brauch</name><affiliation><nlm:aff id="A11">Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A12">University of Tubingen, Tubingen, Germany</nlm:aff></affiliation></author><author><name sortKey="Ko, Yon Dschun" sort="Ko, Yon Dschun" uniqKey="Ko Y" first="Yon-Dschun" last="Ko">Yon-Dschun Ko</name><affiliation><nlm:aff id="A13">Department of Internal Medicine, Evangelische Kliniken Bonn gGmbH, Johanniter Krankenhaus, Bonn, Germany</nlm:aff></affiliation></author><author><name sortKey="Fischer, Hans Peter" sort="Fischer, Hans Peter" uniqKey="Fischer H" first="Hans-Peter" last="Fischer">Hans-Peter Fischer</name><affiliation><nlm:aff id="A14">Institute of Pathology, Medical Faculty of the University of Bonn, Bonn, Germany</nlm:aff></affiliation></author><author><name sortKey="Schmutzler, Rita K" sort="Schmutzler, Rita K" uniqKey="Schmutzler R" first="Rita K." last="Schmutzler">Rita K. Schmutzler</name><affiliation><nlm:aff id="A17">Division of Molecular Gyneco-Oncology, Department of Gynaecology and Obstetrics, Center of Molecular Medicine Cologne (CMMC), University Hospital of Cologne, Cologne, Germany</nlm:aff></affiliation></author><author><name sortKey="Meindl, Alfons" sort="Meindl, Alfons" uniqKey="Meindl A" first="Alfons" last="Meindl">Alfons Meindl</name><affiliation><nlm:aff id="A18">Department for Obstetrica and Gynaecology, Dvision for Tumor Genetics, Klinikum rechts der Isar, Technische Universität, Munich, Germany</nlm:aff></affiliation></author><author><name sortKey="Bartram, Claus R" sort="Bartram, Claus R" uniqKey="Bartram C" first="Claus R." last="Bartram">Claus R. Bartram</name><affiliation><nlm:aff id="A19">Institute of Human Genetics, University of Heidelberg, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Schott, Sarah" sort="Schott, Sarah" uniqKey="Schott S" first="Sarah" last="Schott">Sarah Schott</name><affiliation><nlm:aff id="A20">Department of Obstetrics and Gynecology, University Hospital Heidelberg, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Engel, Christof" sort="Engel, Christof" uniqKey="Engel C" first="Christof" last="Engel">Christof Engel</name><affiliation><nlm:aff id="A21">Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany</nlm:aff></affiliation></author><author><name sortKey="Godwin, Andrew K" sort="Godwin, Andrew K" uniqKey="Godwin A" first="Andrew K." last="Godwin">Andrew K. Godwin</name><affiliation><nlm:aff id="A22">Department of Pathology & Laboratory Medicine, University of Kansas Medical Center, Kansas City, USA</nlm:aff></affiliation></author><author><name sortKey="Weaver, Joellen" sort="Weaver, Joellen" uniqKey="Weaver J" first="Joellen" last="Weaver">Joellen Weaver</name><affiliation><nlm:aff id="A23">Biosample Repository, Fox Chase Cancer Center, Philadelphia, USA</nlm:aff></affiliation></author><author><name sortKey="Pathak, Harsh B" sort="Pathak, Harsh B" uniqKey="Pathak H" first="Harsh B." last="Pathak">Harsh B. Pathak</name><affiliation><nlm:aff id="A22">Department of Pathology & Laboratory Medicine, University of Kansas Medical Center, Kansas City, USA</nlm:aff></affiliation></author><author><name sortKey="Sharma, Priyanka" sort="Sharma, Priyanka" uniqKey="Sharma P" first="Priyanka" last="Sharma">Priyanka Sharma</name><affiliation><nlm:aff id="A24">Division of Hematology and Oncology, University of Kansas Medical Center, Kansas City, USA</nlm:aff></affiliation></author><author><name sortKey="Brenner, Hermann" sort="Brenner, Hermann" uniqKey="Brenner H" first="Hermann" last="Brenner">Hermann Brenner</name><affiliation><nlm:aff id="A25">Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Muller, Heiko" sort="Muller, Heiko" uniqKey="Muller H" first="Heiko" last="Müller">Heiko Müller</name><affiliation><nlm:aff id="A25">Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Arndt, Volker" sort="Arndt, Volker" uniqKey="Arndt V" first="Volker" last="Arndt">Volker Arndt</name><affiliation><nlm:aff id="A25">Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Stegmaier, Christa" sort="Stegmaier, Christa" uniqKey="Stegmaier C" first="Christa" last="Stegmaier">Christa Stegmaier</name><affiliation><nlm:aff id="A26">Saarland Cancer Registry, Saarbrücken, Germany</nlm:aff></affiliation></author><author><name sortKey="Miron, Penelope" sort="Miron, Penelope" uniqKey="Miron P" first="Penelope" last="Miron">Penelope Miron</name><affiliation><nlm:aff id="A27">Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, USA</nlm:aff></affiliation></author><author><name sortKey="Yannoukakos, Drakoulis" sort="Yannoukakos, Drakoulis" uniqKey="Yannoukakos D" first="Drakoulis" last="Yannoukakos">Drakoulis Yannoukakos</name><affiliation><nlm:aff id="A28">Molecular Diagnostics Laboratory, IRRP, National Centre for Scientific Research ‘Demokritos’, Athens, Greece</nlm:aff></affiliation></author><author><name sortKey="Stavropoulou, Alexandra" sort="Stavropoulou, Alexandra" uniqKey="Stavropoulou A" first="Alexandra" last="Stavropoulou">Alexandra Stavropoulou</name><affiliation><nlm:aff id="A28">Molecular Diagnostics Laboratory, IRRP, National Centre for Scientific Research ‘Demokritos’, Athens, Greece</nlm:aff></affiliation></author><author><name sortKey="Fountzilas, George" sort="Fountzilas, George" uniqKey="Fountzilas G" first="George" last="Fountzilas">George Fountzilas</name><affiliation><nlm:aff id="A29">Department of Medical Oncology, “Papageorgiou” Hospital, Ring Road, Aristotle University of Thessaloniki School of Medicine, Thessaloniki, Greece</nlm:aff></affiliation></author><author><name sortKey="Gogas, Helen J" sort="Gogas, Helen J" uniqKey="Gogas H" first="Helen J." last="Gogas">Helen J. Gogas</name><affiliation><nlm:aff id="A30">First Department of Medicine, University of Athens, Medical School, Athens, Greece</nlm:aff></affiliation></author><author><name sortKey="Swann, Ruth" sort="Swann, Ruth" uniqKey="Swann R" first="Ruth" last="Swann">Ruth Swann</name><affiliation><nlm:aff id="A31">Against Breast Cancer Research Unit, School of Life Sciences, University of Westminster, London, UK</nlm:aff></affiliation></author><author><name sortKey="Dwek, Miriam" sort="Dwek, Miriam" uniqKey="Dwek M" first="Miriam" last="Dwek">Miriam Dwek</name><affiliation><nlm:aff id="A31">Against Breast Cancer Research Unit, School of Life Sciences, University of Westminster, London, UK</nlm:aff></affiliation></author><author><name sortKey="Perkins, Annie" sort="Perkins, Annie" uniqKey="Perkins A" first="Annie" last="Perkins">Annie Perkins</name><affiliation><nlm:aff id="A31">Against Breast Cancer Research Unit, School of Life Sciences, University of Westminster, London, UK</nlm:aff></affiliation></author><author><name sortKey="Milne, Roger L" sort="Milne, Roger L" uniqKey="Milne R" first="Roger L." last="Milne">Roger L. Milne</name><affiliation><nlm:aff id="A32">Genetic & Molecular Epidemiology Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain</nlm:aff></affiliation></author><author><name sortKey="Benitez, Javier" sort="Benitez, Javier" uniqKey="Benitez J" first="Javier" last="Benítez">Javier Benítez</name><affiliation><nlm:aff id="A33">Human Genetics Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain</nlm:aff></affiliation></author><author><name sortKey="Zamora, M Pilar" sort="Zamora, M Pilar" uniqKey="Zamora M" first="M Pilar" last="Zamora">M Pilar Zamora</name><affiliation><nlm:aff id="A34">Servicio de Oncología Médica, Hospital Universitario La Paz, Madrid, Spain</nlm:aff></affiliation></author><author><name sortKey="Perez, Jose Ignacio Arias" sort="Perez, Jose Ignacio Arias" uniqKey="Perez J" first="José Ignacio Arias" last="Pérez">José Ignacio Arias Pérez</name><affiliation><nlm:aff id="A35">Servicio de Cirugía General y Especialidades, Hospital Monte Naranco, Oviedo, Spain</nlm:aff></affiliation></author><author><name sortKey="Bojesen, Stig E" sort="Bojesen, Stig E" uniqKey="Bojesen S" first="Stig E." last="Bojesen">Stig E. Bojesen</name><affiliation><nlm:aff id="A36">Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark</nlm:aff></affiliation><affiliation><nlm:aff id="A37">The Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark</nlm:aff></affiliation></author><author><name sortKey="Nielsen, Sune F" sort="Nielsen, Sune F" uniqKey="Nielsen S" first="Sune F." last="Nielsen">Sune F. Nielsen</name><affiliation><nlm:aff id="A36">Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark</nlm:aff></affiliation><affiliation><nlm:aff id="A37">The Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark</nlm:aff></affiliation></author><author><name sortKey="Nordestgaard, B Rge G" sort="Nordestgaard, B Rge G" uniqKey="Nordestgaard B" first="B Rge G" last="Nordestgaard">B Rge G. Nordestgaard</name><affiliation><nlm:aff id="A36">Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark</nlm:aff></affiliation><affiliation><nlm:aff id="A37">The Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark</nlm:aff></affiliation></author><author><name sortKey="Flyger, Henrik" sort="Flyger, Henrik" uniqKey="Flyger H" first="Henrik" last="Flyger">Henrik Flyger</name><affiliation><nlm:aff id="A38">Department of Breast Surgery, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark</nlm:aff></affiliation></author><author><name sortKey="Guenel, Pascal" sort="Guenel, Pascal" uniqKey="Guenel P" first="Pascal" last="Guénel">Pascal Guénel</name><affiliation><nlm:aff id="A39">Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer, Villejuif, France</nlm:aff></affiliation><affiliation><nlm:aff id="A40">University Paris-Sud, UMRS1018 Villejuif, France</nlm:aff></affiliation></author><author><name sortKey="Truong, Therese" sort="Truong, Therese" uniqKey="Truong T" first="Thérèse" last="Truong">Thérèse Truong</name><affiliation><nlm:aff id="A39">Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer, Villejuif, France</nlm:aff></affiliation><affiliation><nlm:aff id="A40">University Paris-Sud, UMRS1018 Villejuif, France</nlm:aff></affiliation></author><author><name sortKey="Menegaux, Florence" sort="Menegaux, Florence" uniqKey="Menegaux F" first="Florence" last="Menegaux">Florence Menegaux</name><affiliation><nlm:aff id="A39">Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer, Villejuif, France</nlm:aff></affiliation><affiliation><nlm:aff id="A40">University Paris-Sud, UMRS1018 Villejuif, France</nlm:aff></affiliation></author><author><name sortKey="Cordina Duverger, Emilie" sort="Cordina Duverger, Emilie" uniqKey="Cordina Duverger E" first="Emilie" last="Cordina-Duverger">Emilie Cordina-Duverger</name><affiliation><nlm:aff id="A39">Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer, Villejuif, France</nlm:aff></affiliation><affiliation><nlm:aff id="A40">University Paris-Sud, UMRS1018 Villejuif, France</nlm:aff></affiliation></author><author><name sortKey="Burwinkel, Barbara" sort="Burwinkel, Barbara" uniqKey="Burwinkel B" first="Barbara" last="Burwinkel">Barbara Burwinkel</name><affiliation><nlm:aff id="A20">Department of Obstetrics and Gynecology, University Hospital Heidelberg, Heidelberg, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A41">Molecular Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Marme, Frederick" sort="Marme, Frederick" uniqKey="Marme F" first="Frederick" last="Marmé">Frederick Marmé</name><affiliation><nlm:aff id="A20">Department of Obstetrics and Gynecology, University Hospital Heidelberg, Heidelberg, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A42">National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Schneeweiss, Andreas" sort="Schneeweiss, Andreas" uniqKey="Schneeweiss A" first="Andreas" last="Schneeweiss">Andreas Schneeweiss</name><affiliation><nlm:aff id="A20">Department of Obstetrics and Gynecology, University Hospital Heidelberg, Heidelberg, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A42">National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Sohn, Christof" sort="Sohn, Christof" uniqKey="Sohn C" first="Christof" last="Sohn">Christof Sohn</name><affiliation><nlm:aff id="A20">Department of Obstetrics and Gynecology, University Hospital Heidelberg, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Sawyer, Elinor" sort="Sawyer, Elinor" uniqKey="Sawyer E" first="Elinor" last="Sawyer">Elinor Sawyer</name><affiliation><nlm:aff id="A43">National Institute for Health Research (NIHR) Comprehensive Biomedical Research Centre, Guy’s & St. Thomas’ NHS Foundation Trust in partnership with King’s College London and King’s College Hospital NHS Foundation Trus, London, UK</nlm:aff></affiliation></author><author><name sortKey="Tomlinson, Ian" sort="Tomlinson, Ian" uniqKey="Tomlinson I" first="Ian" last="Tomlinson">Ian Tomlinson</name><affiliation><nlm:aff id="A44">Welcome Trust Centre for Human Genetics and Oxford Biomedical Research Centre, University of Oxford, Oxford, UK</nlm:aff></affiliation></author><author><name sortKey="Kerin, Michael J" sort="Kerin, Michael J" uniqKey="Kerin M" first="Michael J." last="Kerin">Michael J. Kerin</name><affiliation><nlm:aff id="A45">NUIG Department of Surgery, Clinical Science Institute, University Hospital Galway, Galway, Ireland</nlm:aff></affiliation></author><author><name sortKey="Peto, Julian" sort="Peto, Julian" uniqKey="Peto J" first="Julian" last="Peto">Julian Peto</name><affiliation><nlm:aff id="A46">Department of Nion-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK</nlm:aff></affiliation></author><author><name sortKey="Johnson, Nichola" sort="Johnson, Nichola" uniqKey="Johnson N" first="Nichola" last="Johnson">Nichola Johnson</name><affiliation><nlm:aff id="A47">Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK</nlm:aff></affiliation></author><author><name sortKey="Fletcher, Olivia" sort="Fletcher, Olivia" uniqKey="Fletcher O" first="Olivia" last="Fletcher">Olivia Fletcher</name><affiliation><nlm:aff id="A47">Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK</nlm:aff></affiliation></author><author><name sortKey="Silva, Isabel Dos Santos" sort="Silva, Isabel Dos Santos" uniqKey="Silva I" first="Isabel Dos Santos" last="Silva">Isabel Dos Santos Silva</name><affiliation><nlm:aff id="A48">Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK</nlm:aff></affiliation></author><author><name sortKey="Fasching, Peter A" sort="Fasching, Peter A" uniqKey="Fasching P" first="Peter A." last="Fasching">Peter A. Fasching</name><affiliation><nlm:aff id="A49">University of California at Los Angeles, David Geffen School of Medicine, Department of Medicine, Division of Hematology and Oncology, Los Angeles, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A50">University Breast Center Franconia, Department of Gynecology and Obstetrics, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center, Erlangen-Nuremberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Beckmann, Matthias W" sort="Beckmann, Matthias W" uniqKey="Beckmann M" first="Matthias W." last="Beckmann">Matthias W. Beckmann</name><affiliation><nlm:aff id="A50">University Breast Center Franconia, Department of Gynecology and Obstetrics, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center, Erlangen-Nuremberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Hartmann, Arndt" sort="Hartmann, Arndt" uniqKey="Hartmann A" first="Arndt" last="Hartmann">Arndt Hartmann</name><affiliation><nlm:aff id="A51">Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen-Nuremberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Ekici, Arif B" sort="Ekici, Arif B" uniqKey="Ekici A" first="Arif B." last="Ekici">Arif B. Ekici</name><affiliation><nlm:aff id="A52">Institute of Human Genetics, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen-Nuremberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Lophatananon, Artitaya" sort="Lophatananon, Artitaya" uniqKey="Lophatananon A" first="Artitaya" last="Lophatananon">Artitaya Lophatananon</name><affiliation><nlm:aff id="A53">Health Sciences Research Institute, Warwick Medical School, Warwick University, Coventry, UK</nlm:aff></affiliation></author><author><name sortKey="Muir, Kenneth" sort="Muir, Kenneth" uniqKey="Muir K" first="Kenneth" last="Muir">Kenneth Muir</name><affiliation><nlm:aff id="A53">Health Sciences Research Institute, Warwick Medical School, Warwick University, Coventry, UK</nlm:aff></affiliation></author><author><name sortKey="Puttawibul, Puttisak" sort="Puttawibul, Puttisak" uniqKey="Puttawibul P" first="Puttisak" last="Puttawibul">Puttisak Puttawibul</name><affiliation><nlm:aff id="A54">Department of Surgery, Medical school, Prince Songkla University, Songkla, Thailand</nlm:aff></affiliation></author><author><name sortKey="Wiangnon, Surapon" sort="Wiangnon, Surapon" uniqKey="Wiangnon S" first="Surapon" last="Wiangnon">Surapon Wiangnon</name><affiliation><nlm:aff id="A55">Department of Pediatrics, Medical school, Khon Kaen University, Khon Kaen, Thailand</nlm:aff></affiliation></author><author><name sortKey="Schmidt, Marjanka K" sort="Schmidt, Marjanka K" uniqKey="Schmidt M" first="Marjanka K" last="Schmidt">Marjanka K. Schmidt</name><affiliation><nlm:aff id="A56">Netherlands Cancer Institute, Amsterdam, Netherlands</nlm:aff></affiliation></author><author><name sortKey="Broeks, Annegien" sort="Broeks, Annegien" uniqKey="Broeks A" first="Annegien" last="Broeks">Annegien Broeks</name><affiliation><nlm:aff id="A56">Netherlands Cancer Institute, Amsterdam, Netherlands</nlm:aff></affiliation></author><author><name sortKey="Braaf, Linde M" sort="Braaf, Linde M" uniqKey="Braaf L" first="Linde M" last="Braaf">Linde M. Braaf</name><affiliation><nlm:aff id="A56">Netherlands Cancer Institute, Amsterdam, Netherlands</nlm:aff></affiliation></author><author><name sortKey="Rosenberg, Efraim H" sort="Rosenberg, Efraim H" uniqKey="Rosenberg E" first="Efraim H" last="Rosenberg">Efraim H. Rosenberg</name><affiliation><nlm:aff id="A56">Netherlands Cancer Institute, Amsterdam, Netherlands</nlm:aff></affiliation></author><author><name sortKey="Hopper, John L" sort="Hopper, John L" uniqKey="Hopper J" first="John L." last="Hopper">John L. Hopper</name><affiliation><nlm:aff id="A57">Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia</nlm:aff></affiliation></author><author><name sortKey="Apicella, Carmel" sort="Apicella, Carmel" uniqKey="Apicella C" first="Carmel" last="Apicella">Carmel Apicella</name><affiliation><nlm:aff id="A57">Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia</nlm:aff></affiliation></author><author><name sortKey="Park, Daniel J" sort="Park, Daniel J" uniqKey="Park D" first="Daniel J." last="Park">Daniel J. Park</name><affiliation><nlm:aff id="A58">Department of Pathology, The University of Melbourne, Melbourne, Australia</nlm:aff></affiliation></author><author><name sortKey="Southey, Melissa C" sort="Southey, Melissa C" uniqKey="Southey M" first="Melissa C." last="Southey">Melissa C. Southey</name><affiliation><nlm:aff id="A58">Department of Pathology, The University of Melbourne, Melbourne, Australia</nlm:aff></affiliation></author><author><name sortKey="Swerdlow, Anthony J" sort="Swerdlow, Anthony J" uniqKey="Swerdlow A" first="Anthony J." last="Swerdlow">Anthony J. Swerdlow</name><affiliation><nlm:aff id="A59">Section of Epidemiology, Institute of Cancer Research., Sutton,, UK</nlm:aff></affiliation></author><author><name sortKey="Ashworth, Alan" sort="Ashworth, Alan" uniqKey="Ashworth A" first="Alan" last="Ashworth">Alan Ashworth</name><affiliation><nlm:aff id="A60">The Breakthrough Breast Cancer Research Centre, Institute of Cancer Research., London, UK</nlm:aff></affiliation></author><author><name sortKey="Orr, Nicholas" sort="Orr, Nicholas" uniqKey="Orr N" first="Nicholas" last="Orr">Nicholas Orr</name><affiliation><nlm:aff id="A60">The Breakthrough Breast Cancer Research Centre, Institute of Cancer Research., London, UK</nlm:aff></affiliation></author><author><name sortKey="Schoemaker, Minouk J" sort="Schoemaker, Minouk J" uniqKey="Schoemaker M" first="Minouk J." last="Schoemaker">Minouk J. Schoemaker</name><affiliation><nlm:aff id="A59">Section of Epidemiology, Institute of Cancer Research., Sutton,, UK</nlm:aff></affiliation></author><author><name sortKey="Anton Culver, Hoda" sort="Anton Culver, Hoda" uniqKey="Anton Culver H" first="Hoda" last="Anton-Culver">Hoda Anton-Culver</name><affiliation><nlm:aff id="A61">Department of Epidemiology, School of Medicine, University of California Irvine, Irvine, CA</nlm:aff></affiliation></author><author><name sortKey="Ziogas, Argyrios" sort="Ziogas, Argyrios" uniqKey="Ziogas A" first="Argyrios" last="Ziogas">Argyrios Ziogas</name><affiliation><nlm:aff id="A61">Department of Epidemiology, School of Medicine, University of California Irvine, Irvine, CA</nlm:aff></affiliation></author><author><name sortKey="Bernstein, Leslie" sort="Bernstein, Leslie" uniqKey="Bernstein L" first="Leslie" last="Bernstein">Leslie Bernstein</name><affiliation><nlm:aff id="A62">Division of Cancer Etiology, Department of Population Sciences, Beckman Research Institute, City of Hope</nlm:aff></affiliation></author><author><name sortKey="Dur, Christina Clarke" sort="Dur, Christina Clarke" uniqKey="Dur C" first="Christina Clarke" last="Dur">Christina Clarke Dur</name><affiliation><nlm:aff id="A63">Department of Epidemiology, Cancer Prevention Institute of California, Fremont, CA</nlm:aff></affiliation></author><author><name sortKey="Shen, Chen Yang" sort="Shen, Chen Yang" uniqKey="Shen C" first="Chen-Yang" last="Shen">Chen-Yang Shen</name><affiliation><nlm:aff id="A64">Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan</nlm:aff></affiliation></author><author><name sortKey="Yu, Jyh Cherng" sort="Yu, Jyh Cherng" uniqKey="Yu J" first="Jyh-Cherng" last="Yu">Jyh-Cherng Yu</name><affiliation><nlm:aff id="A65">Department of Surgery, Tri-Service General Hospital, Taipei, Taiwan</nlm:aff></affiliation></author><author><name sortKey="Hsu, Huan Ming" sort="Hsu, Huan Ming" uniqKey="Hsu H" first="Huan-Ming" last="Hsu">Huan-Ming Hsu</name><affiliation><nlm:aff id="A65">Department of Surgery, Tri-Service General Hospital, Taipei, Taiwan</nlm:aff></affiliation></author><author><name sortKey="Hsiung, Chia Ni" sort="Hsiung, Chia Ni" uniqKey="Hsiung C" first="Chia-Ni" last="Hsiung">Chia-Ni Hsiung</name><affiliation><nlm:aff id="A64">Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan</nlm:aff></affiliation></author><author><name sortKey="Hamann, Ute" sort="Hamann, Ute" uniqKey="Hamann U" first="Ute" last="Hamann">Ute Hamann</name><affiliation><nlm:aff id="A66">Molecular Genetics of Breast Cancer, Deutsches Krebsforschungsfzentrum (DKFZ), Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Dunnebier, Thomas" sort="Dunnebier, Thomas" uniqKey="Dunnebier T" first="Thomas" last="Dünnebier">Thomas Dünnebier</name><affiliation><nlm:aff id="A66">Molecular Genetics of Breast Cancer, Deutsches Krebsforschungsfzentrum (DKFZ), Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Rudiger, Thomas" sort="Rudiger, Thomas" uniqKey="Rudiger T" first="Thomas" last="Rüdiger">Thomas Rüdiger</name><affiliation><nlm:aff id="A67">Institute of Pathology, Städtisches Klinikum Karlsruhe, Karlsruhe, Germany</nlm:aff></affiliation></author><author><name sortKey="Ulmer, Hans Ulrich" sort="Ulmer, Hans Ulrich" uniqKey="Ulmer H" first="Hans Ulrich" last="Ulmer">Hans Ulrich Ulmer</name><affiliation><nlm:aff id="A68">Women’s Clinic, Städtisches Klinikum Karlsruhe, Karlsruhe, Germany</nlm:aff></affiliation></author><author><name sortKey="Pharoah, Paul P" sort="Pharoah, Paul P" uniqKey="Pharoah P" first="Paul P." last="Pharoah">Paul P. Pharoah</name><affiliation><nlm:aff id="A69">Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK</nlm:aff></affiliation><affiliation><nlm:aff id="A70">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Dunning, Alison M" sort="Dunning, Alison M" uniqKey="Dunning A" first="Alison M" last="Dunning">Alison M. Dunning</name><affiliation><nlm:aff id="A69">Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Humphreys, Manjeet K" sort="Humphreys, Manjeet K" uniqKey="Humphreys M" first="Manjeet K." last="Humphreys">Manjeet K. Humphreys</name><affiliation><nlm:aff id="A70">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Wang, Qin" sort="Wang, Qin" uniqKey="Wang Q" first="Qin" last="Wang">Qin Wang</name><affiliation><nlm:aff id="A70">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Cox, Angela" sort="Cox, Angela" uniqKey="Cox A" first="Angela" last="Cox">Angela Cox</name><affiliation><nlm:aff id="A71">Dept of Oncology, Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, UK</nlm:aff></affiliation></author><author><name sortKey="Cross, Simon S" sort="Cross, Simon S" uniqKey="Cross S" first="Simon S." last="Cross">Simon S. Cross</name><affiliation><nlm:aff id="A72">Department of Neuroscience, Faculty of Medicine, Dentistry & Health, University of Sheffield, Sheffield, UK</nlm:aff></affiliation></author><author><name sortKey="Reed, Malcom W" sort="Reed, Malcom W" uniqKey="Reed M" first="Malcom W." last="Reed">Malcom W. Reed</name><affiliation><nlm:aff id="A71">Dept of Oncology, Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, UK</nlm:aff></affiliation></author><author><name sortKey="Hall, Per" sort="Hall, Per" uniqKey="Hall P" first="Per" last="Hall">Per Hall</name><affiliation><nlm:aff id="A73">Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</nlm:aff></affiliation></author><author><name sortKey="Czene, Kamila" sort="Czene, Kamila" uniqKey="Czene K" first="Kamila" last="Czene">Kamila Czene</name><affiliation><nlm:aff id="A73">Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</nlm:aff></affiliation></author><author><name sortKey="Ambrosone, Christine B" sort="Ambrosone, Christine B" uniqKey="Ambrosone C" first="Christine B." last="Ambrosone">Christine B. Ambrosone</name><affiliation><nlm:aff id="A74">Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, USA</nlm:aff></affiliation></author><author><name sortKey="Ademuyiwa, Foluso" sort="Ademuyiwa, Foluso" uniqKey="Ademuyiwa F" first="Foluso" last="Ademuyiwa">Foluso Ademuyiwa</name><affiliation><nlm:aff id="A75">Department of Medicine, Roswell Park Cancer Institute, Buffalo, USA</nlm:aff></affiliation></author><author><name sortKey="Hwang, Helena" sort="Hwang, Helena" uniqKey="Hwang H" first="Helena" last="Hwang">Helena Hwang</name><affiliation><nlm:aff id="A76">Department of Pathology, Roswell Park Cancer Institute, Buffalo, USA</nlm:aff></affiliation></author><author><name sortKey="Eccles, Diana M" sort="Eccles, Diana M" uniqKey="Eccles D" first="Diana M." last="Eccles">Diana M. Eccles</name><affiliation><nlm:aff id="A77">Faculty of Medicine, University of Southampton, Southampton, UK</nlm:aff></affiliation></author><author><name sortKey="Garcia Closas, Montserrat" sort="Garcia Closas, Montserrat" uniqKey="Garcia Closas M" first="Montserrat" last="Garcia-Closas">Montserrat Garcia-Closas</name><affiliation><nlm:aff id="A78">Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, UK</nlm:aff></affiliation></author><author><name sortKey="Figueroa, Jonine D" sort="Figueroa, Jonine D" uniqKey="Figueroa J" first="Jonine D." last="Figueroa">Jonine D. Figueroa</name><affiliation><nlm:aff id="A79">Division of Cancer Epidemiology and Genetics, Hormonal and Reproductive Epidemiology Branch, NIH/NCI, Bethesda, USA</nlm:aff></affiliation></author><author><name sortKey="Sherman, Mark E" sort="Sherman, Mark E" uniqKey="Sherman M" first="Mark E." last="Sherman">Mark E. Sherman</name><affiliation><nlm:aff id="A79">Division of Cancer Epidemiology and Genetics, Hormonal and Reproductive Epidemiology Branch, NIH/NCI, Bethesda, USA</nlm:aff></affiliation></author><author><name sortKey="Lissowska, Jolanta" sort="Lissowska, Jolanta" uniqKey="Lissowska J" first="Jolanta" last="Lissowska">Jolanta Lissowska</name><affiliation><nlm:aff id="A80">Department of Cancer Epidemiology and Prevention, The M. Sklodowska-Curie Cancer Center and Institute of Oncology, Warsaw, Poland</nlm:aff></affiliation></author><author><name sortKey="Devilee, Peter" sort="Devilee, Peter" uniqKey="Devilee P" first="Peter" last="Devilee">Peter Devilee</name><affiliation><nlm:aff id="A81">Department of Human Genetics & Department of Pathology, Leiden University Medical Center, Leiden, Netherlands</nlm:aff></affiliation></author><author><name sortKey="Seynaeve, Caroline" sort="Seynaeve, Caroline" uniqKey="Seynaeve C" first="Caroline" last="Seynaeve">Caroline Seynaeve</name><affiliation><nlm:aff id="A82">Department of Medical Oncology, Erasmus Medical Center, Daniel den Hoed Cancer Center, Rotterdam, Netherlands</nlm:aff></affiliation></author><author><name sortKey="Tollenaar, R A E M" sort="Tollenaar, R A E M" uniqKey="Tollenaar R" first="R. A. E. M." last="Tollenaar">R. A. E. M. Tollenaar</name><affiliation><nlm:aff id="A83">Department of Surgical Oncology, Leiden University Medical Center, Leiden, Netherlands</nlm:aff></affiliation></author><author><name sortKey="Hooning, Maartje J" sort="Hooning, Maartje J" uniqKey="Hooning M" first="Maartje J." last="Hooning">Maartje J. Hooning</name><affiliation><nlm:aff id="A82">Department of Medical Oncology, Erasmus Medical Center, Daniel den Hoed Cancer Center, Rotterdam, Netherlands</nlm:aff></affiliation></author><author><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L." last="Andrulis">Irene L. Andrulis</name><affiliation><nlm:aff id="A84">Departments of Molecular Genetics and Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada</nlm:aff></affiliation></author><author><name sortKey="Knight, Julia A" sort="Knight, Julia A" uniqKey="Knight J" first="Julia A." last="Knight">Julia A. Knight</name><affiliation><nlm:aff id="A85">Dalla Lana School of Public Health, University of Toronto, Prosserman Centre for Health Research, Toronto, Canada</nlm:aff></affiliation></author><author><name sortKey="Glendon, Gord" sort="Glendon, Gord" uniqKey="Glendon G" first="Gord" last="Glendon">Gord Glendon</name><affiliation><nlm:aff id="A86">Cancer Care Ontario, Princess Margaret Hospital, Toronto, Canada</nlm:aff></affiliation></author><author><name sortKey="Mulligan, Anna Marie" sort="Mulligan, Anna Marie" uniqKey="Mulligan A" first="Anna Marie" last="Mulligan">Anna Marie Mulligan</name><affiliation><nlm:aff id="A87">Department of Laboratory Medicine, Keenan Research Centre of the Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, Canada</nlm:aff></affiliation></author><author><name sortKey="Winqvist, Robert" sort="Winqvist, Robert" uniqKey="Winqvist R" first="Robert" last="Winqvist">Robert Winqvist</name><affiliation><nlm:aff id="A88">Department of Clinical Genetics, Institute of Clinical Medicine, Biocenter Oulu, University of Oulu, Oulu University Hospital, Oulu, Finland</nlm:aff></affiliation></author><author><name sortKey="Pylk S, Katri" sort="Pylk S, Katri" uniqKey="Pylk S K" first="Katri" last="Pylk S">Katri Pylk S</name><affiliation><nlm:aff id="A88">Department of Clinical Genetics, Institute of Clinical Medicine, Biocenter Oulu, University of Oulu, Oulu University Hospital, Oulu, Finland</nlm:aff></affiliation></author><author><name sortKey="Jukkola Vuorinen, Arja" sort="Jukkola Vuorinen, Arja" uniqKey="Jukkola Vuorinen A" first="Arja" last="Jukkola-Vuorinen">Arja Jukkola-Vuorinen</name><affiliation><nlm:aff id="A89">Department of Oncology, University of Oulu, Oulu University Hospital, Oulu, Finland</nlm:aff></affiliation></author><author><name sortKey="Grip, Mervi" sort="Grip, Mervi" uniqKey="Grip M" first="Mervi" last="Grip">Mervi Grip</name><affiliation><nlm:aff id="A90">Department of Surgery, University of Oulu, Oulu University Hospital, Oulu, Finland</nlm:aff></affiliation></author><author><name sortKey="John, Esther M" sort="John, Esther M" uniqKey="John E" first="Esther M." last="John">Esther M. John</name><affiliation><nlm:aff id="A63">Department of Epidemiology, Cancer Prevention Institute of California, Fremont, CA</nlm:aff></affiliation></author><author><name sortKey="Miron, Alexander" sort="Miron, Alexander" uniqKey="Miron A" first="Alexander" last="Miron">Alexander Miron</name><affiliation><nlm:aff id="A27">Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, USA</nlm:aff></affiliation></author><author><name sortKey="Aln S, Grethe Grenaker" sort="Aln S, Grethe Grenaker" uniqKey="Aln S G" first="Grethe Grenaker" last="Aln S">Grethe Grenaker Aln S</name><affiliation><nlm:aff id="A91">Institute for Clinical Epidemiology and Molecular Biology (EpiGen), Faculty of Medicine, University of Oslo, Oslo, Norway</nlm:aff></affiliation><affiliation><nlm:aff id="A92">Group of Cancer Genome Variation Department of Genetics, Institute for Cancer Research, Oslo, Norway</nlm:aff></affiliation></author><author><name sortKey="Kristensen, Vessela" sort="Kristensen, Vessela" uniqKey="Kristensen V" first="Vessela" last="Kristensen">Vessela Kristensen</name><affiliation><nlm:aff id="A91">Institute for Clinical Epidemiology and Molecular Biology (EpiGen), Faculty of Medicine, University of Oslo, Oslo, Norway</nlm:aff></affiliation><affiliation><nlm:aff id="A92">Group of Cancer Genome Variation Department of Genetics, Institute for Cancer Research, Oslo, Norway</nlm:aff></affiliation></author><author><name sortKey="B Rresen Dale, Anne Lise" sort="B Rresen Dale, Anne Lise" uniqKey="B Rresen Dale A" first="Anne-Lise" last="B Rresen-Dale">Anne-Lise B Rresen-Dale</name><affiliation><nlm:aff id="A93">Department of Genetics, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo, Norway</nlm:aff></affiliation></author><author><name sortKey="Giles, Graham G" sort="Giles, Graham G" uniqKey="Giles G" first="Graham G." last="Giles">Graham G. Giles</name><affiliation><nlm:aff id="A94">Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Australia</nlm:aff></affiliation><affiliation><nlm:aff id="A95">Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia</nlm:aff></affiliation></author><author><name sortKey="Baglietto, Laura" sort="Baglietto, Laura" uniqKey="Baglietto L" first="Laura" last="Baglietto">Laura Baglietto</name><affiliation><nlm:aff id="A94">Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Australia</nlm:aff></affiliation><affiliation><nlm:aff id="A95">Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia</nlm:aff></affiliation></author><author><name sortKey="Mclean, Catriona A" sort="Mclean, Catriona A" uniqKey="Mclean C" first="Catriona A" last="Mclean">Catriona A. Mclean</name><affiliation><nlm:aff id="A96">The Alfred Hospital, Melbourne, Australia</nlm:aff></affiliation></author><author><name sortKey="Severi, Gianluca" sort="Severi, Gianluca" uniqKey="Severi G" first="Gianluca" last="Severi">Gianluca Severi</name><affiliation><nlm:aff id="A94">Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Australia</nlm:aff></affiliation><affiliation><nlm:aff id="A95">Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia</nlm:aff></affiliation></author><author><name sortKey="Kosel, Matthew L" sort="Kosel, Matthew L" uniqKey="Kosel M" first="Matthew L." last="Kosel">Matthew L. Kosel</name><affiliation><nlm:aff id="A1">Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota</nlm:aff></affiliation></author><author><name sortKey="Pankratz, V S" sort="Pankratz, V S" uniqKey="Pankratz V" first="V. S." last="Pankratz">V. S. Pankratz</name><affiliation><nlm:aff id="A1">Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota</nlm:aff></affiliation></author><author><name sortKey="Slager, Susan" sort="Slager, Susan" uniqKey="Slager S" first="Susan" last="Slager">Susan Slager</name><affiliation><nlm:aff id="A1">Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota</nlm:aff></affiliation></author><author><name sortKey="Olson, Janet E" sort="Olson, Janet E" uniqKey="Olson J" first="Janet E." last="Olson">Janet E. Olson</name><affiliation><nlm:aff id="A1">Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota</nlm:aff></affiliation></author><author><name sortKey="Radice, Paolo" sort="Radice, Paolo" uniqKey="Radice P" first="Paolo" last="Radice">Paolo Radice</name><affiliation><nlm:aff id="A97">Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale, Tumori (INT), Milan, Italy</nlm:aff></affiliation><affiliation><nlm:aff id="A98">IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy</nlm:aff></affiliation></author><author><name sortKey="Peterlongo, Paolo" sort="Peterlongo, Paolo" uniqKey="Peterlongo P" first="Paolo" last="Peterlongo">Paolo Peterlongo</name><affiliation><nlm:aff id="A97">Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale, Tumori (INT), Milan, Italy</nlm:aff></affiliation><affiliation><nlm:aff id="A98">IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy</nlm:aff></affiliation></author><author><name sortKey="Manoukian, Siranoush" sort="Manoukian, Siranoush" uniqKey="Manoukian S" first="Siranoush" last="Manoukian">Siranoush Manoukian</name><affiliation><nlm:aff id="A99">Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy</nlm:aff></affiliation></author><author><name sortKey="Barile, Monica" sort="Barile, Monica" uniqKey="Barile M" first="Monica" last="Barile">Monica Barile</name><affiliation><nlm:aff id="A100">Division of Cancer Prevention and Genetics, Chemoprevention, European Institute of Oncology, Milan, Italy</nlm:aff></affiliation></author><author><name sortKey="Lambrechts, Diether" sort="Lambrechts, Diether" uniqKey="Lambrechts D" first="Diether" last="Lambrechts">Diether Lambrechts</name><affiliation><nlm:aff id="A101">Vesalius Research Center, VIB, Leuven, Belgium</nlm:aff></affiliation><affiliation><nlm:aff id="A102">Vesalius Research Center, University of Leuven, Leuven, Belgium</nlm:aff></affiliation></author><author><name sortKey="Hatse, Sigrid" sort="Hatse, Sigrid" uniqKey="Hatse S" first="Sigrid" last="Hatse">Sigrid Hatse</name><affiliation><nlm:aff id="A103">Multidisciplinary Breast Center, University Hospital Gasthuisberg, Leuven, Belgium</nlm:aff></affiliation></author><author><name sortKey="Dieudonne, Anne Sophie" sort="Dieudonne, Anne Sophie" uniqKey="Dieudonne A" first="Anne-Sophie" last="Dieudonne">Anne-Sophie Dieudonne</name><affiliation><nlm:aff id="A103">Multidisciplinary Breast Center, University Hospital Gasthuisberg, Leuven, Belgium</nlm:aff></affiliation></author><author><name sortKey="Christiaens, Marie Rose" sort="Christiaens, Marie Rose" uniqKey="Christiaens M" first="Marie-Rose" last="Christiaens">Marie-Rose Christiaens</name><affiliation><nlm:aff id="A103">Multidisciplinary Breast Center, University Hospital Gasthuisberg, Leuven, Belgium</nlm:aff></affiliation></author><author><name sortKey="Chenevix Trench, Georgia" sort="Chenevix Trench, Georgia" uniqKey="Chenevix Trench G" first="Georgia" last="Chenevix-Trench">Georgia Chenevix-Trench</name><affiliation><nlm:aff id="A104">Queensland Institute of Medical Research, Herston, Australia</nlm:aff></affiliation></author><author><name sortKey="Beesley, Jonathan" sort="Beesley, Jonathan" uniqKey="Beesley J" first="Jonathan" last="Beesley">Jonathan Beesley</name><affiliation><nlm:aff id="A104">Queensland Institute of Medical Research, Herston, Australia</nlm:aff></affiliation></author><author><name sortKey="Chen, Xiaoqing" sort="Chen, Xiaoqing" uniqKey="Chen X" first="Xiaoqing" last="Chen">Xiaoqing Chen</name><affiliation><nlm:aff id="A104">Queensland Institute of Medical Research, Herston, Australia</nlm:aff></affiliation></author><author><name sortKey="Mannermaa, Arto" sort="Mannermaa, Arto" uniqKey="Mannermaa A" first="Arto" last="Mannermaa">Arto Mannermaa</name><affiliation><nlm:aff id="A106">Institute of Clinical Medicine, Department of Pathology, University of Eastern Finland and Kuopio University Hospital, Biocenter Kuopio, Kuopio, Finland</nlm:aff></affiliation></author><author><name sortKey="Kosma, Veli Matti" sort="Kosma, Veli Matti" uniqKey="Kosma V" first="Veli-Matti" last="Kosma">Veli-Matti Kosma</name><affiliation><nlm:aff id="A106">Institute of Clinical Medicine, Department of Pathology, University of Eastern Finland and Kuopio University Hospital, Biocenter Kuopio, Kuopio, Finland</nlm:aff></affiliation></author><author><name sortKey="Hartikainen, Jaana M" sort="Hartikainen, Jaana M" uniqKey="Hartikainen J" first="Jaana M." last="Hartikainen">Jaana M. Hartikainen</name><affiliation><nlm:aff id="A106">Institute of Clinical Medicine, Department of Pathology, University of Eastern Finland and Kuopio University Hospital, Biocenter Kuopio, Kuopio, Finland</nlm:aff></affiliation></author><author><name sortKey="Soini, Ylermi" sort="Soini, Ylermi" uniqKey="Soini Y" first="Ylermi" last="Soini">Ylermi Soini</name><affiliation><nlm:aff id="A106">Institute of Clinical Medicine, Department of Pathology, University of Eastern Finland and Kuopio University Hospital, Biocenter Kuopio, Kuopio, Finland</nlm:aff></affiliation></author><author><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F." last="Easton">Douglas F. Easton</name><affiliation><nlm:aff id="A68">Women’s Clinic, Städtisches Klinikum Karlsruhe, Karlsruhe, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="A69">Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Couch, Fergus J" sort="Couch, Fergus J" uniqKey="Couch F" first="Fergus J." last="Couch">Fergus J. Couch</name><affiliation><nlm:aff id="A2">Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota</nlm:aff></affiliation></author></analytic><series><title level="j">Cancer Research</title><idno type="ISSN">0008-5472</idno><idno type="eISSN">1538-7445</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">The 19p13.1 breast cancer susceptibility locus is a modifier of breast cancer risk in BRCA1 mutation carriers and is also associated with risk of ovarian cancer. Here we investigated 19p13.1 variation and risk of breast cancer subtypes, defined by estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor-2 (HER2) status, using 48,869 breast cancer cases and 49,787 controls from the Breast Cancer Association Consortium (BCAC). Variants from 19p13.1 were not associated with breast cancer overall or with ER-positive breast cancer but were significantly associated with ER-negative breast cancer risk [rs8170 Odds Ratio (OR)=1.10, 95% Confidence Interval (CI) 1.05 – 1.15, p=3.49 × 10-5] and triple negative (TN) (ER, PR and HER2 negative) breast cancer [rs8170 OR=1.22, 95% CI 1.13 – 1.31, p=2.22 × 10-7]. However, rs8170 was no longer associated with ER-negative breast cancer risk when TN cases were excluded [OR=0.98, 95% CI 0.89 – 1.07, p=0.62]. In addition, a combined analysis of TN cases from BCAC and the Triple Negative Breast Cancer Consortium (TNBCC) (n=3,566) identified a genome-wide significant association between rs8170 and TN breast cancer risk [OR=1.25, 95% CI 1.18 – 1.33, p=3.31 × 10-13]. Thus, 19p13.1 is the first triple negative-specific breast cancer risk locus and the first locus specific to a histological subtype defined by ER, PR, and HER2 to be identified. These findings provide convincing evidence that genetic susceptibility to breast cancer varies by tumor subtype and that triple negative tumors and other subtypes likely arise through distinct etiologic pathways.</p></div></front></TEI><pmc article-type="research-article" xml:lang="en"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">2984705R</journal-id><journal-id journal-id-type="pubmed-jr-id">2786</journal-id><journal-id journal-id-type="nlm-ta">Cancer Res</journal-id><journal-id journal-id-type="iso-abbrev">Cancer Res.</journal-id><journal-title-group><journal-title>Cancer Research</journal-title></journal-title-group><issn pub-type="ppub">0008-5472</issn><issn pub-type="epub">1538-7445</issn></journal-meta><article-meta><article-id pub-id-type="pmid">22331459</article-id><article-id pub-id-type="pmc">3319792</article-id><article-id pub-id-type="doi">10.1158/0008-5472.CAN-11-3364</article-id><article-id pub-id-type="manuscript">NIHMS357447</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>19p13.1 is a triple negative-specific breast cancer susceptibility locus</article-title></title-group><contrib-group><contrib 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Clarke</given-names></name><xref rid="A63" ref-type="aff">63</xref></contrib><contrib contrib-type="author"><name><surname>Shen</surname><given-names>Chen-Yang</given-names></name><xref rid="A64" ref-type="aff">64</xref></contrib><contrib contrib-type="author"><name><surname>Yu</surname><given-names>Jyh-Cherng</given-names></name><xref rid="A65" ref-type="aff">65</xref></contrib><contrib contrib-type="author"><name><surname>Hsu</surname><given-names>Huan-Ming</given-names></name><xref rid="A65" ref-type="aff">65</xref></contrib><contrib contrib-type="author"><name><surname>Hsiung</surname><given-names>Chia-Ni</given-names></name><xref rid="A64" ref-type="aff">64</xref></contrib><contrib contrib-type="author"><name><surname>Hamann</surname><given-names>Ute</given-names></name><xref rid="A66" ref-type="aff">66</xref></contrib><contrib contrib-type="author"><name><surname>Dünnebier</surname><given-names>Thomas</given-names></name><xref rid="A66" ref-type="aff">66</xref></contrib><contrib contrib-type="author"><name><surname>Rüdiger</surname><given-names>Thomas</given-names></name><xref rid="A67" ref-type="aff">67</xref></contrib><contrib contrib-type="author"><name><surname>Ulmer</surname><given-names>Hans Ulrich</given-names></name><xref rid="A68" ref-type="aff">68</xref></contrib><contrib contrib-type="author"><name><surname>Pharoah</surname><given-names>Paul P.</given-names></name><xref rid="A69" ref-type="aff">69</xref><xref rid="A70" ref-type="aff">70</xref></contrib><contrib contrib-type="author"><name><surname>Dunning</surname><given-names>Alison M</given-names></name><xref rid="A69" ref-type="aff">69</xref></contrib><contrib contrib-type="author"><name><surname>Humphreys</surname><given-names>Manjeet K.</given-names></name><xref rid="A70" ref-type="aff">70</xref></contrib><contrib contrib-type="author"><name><surname>Wang</surname><given-names>Qin</given-names></name><xref rid="A70" ref-type="aff">70</xref></contrib><contrib contrib-type="author"><name><surname>Cox</surname><given-names>Angela</given-names></name><xref rid="A71" ref-type="aff">71</xref></contrib><contrib contrib-type="author"><name><surname>Cross</surname><given-names>Simon S.</given-names></name><xref rid="A72" ref-type="aff">72</xref></contrib><contrib contrib-type="author"><name><surname>Reed</surname><given-names>Malcom W.</given-names></name><xref rid="A71" ref-type="aff">71</xref></contrib><contrib contrib-type="author"><name><surname>Hall</surname><given-names>Per</given-names></name><xref rid="A73" ref-type="aff">73</xref></contrib><contrib contrib-type="author"><name><surname>Czene</surname><given-names>Kamila</given-names></name><xref rid="A73" ref-type="aff">73</xref></contrib><contrib contrib-type="author"><name><surname>Ambrosone</surname><given-names>Christine B.</given-names></name><xref rid="A74" ref-type="aff">74</xref></contrib><contrib contrib-type="author"><name><surname>Ademuyiwa</surname><given-names>Foluso</given-names></name><xref rid="A75" ref-type="aff">75</xref></contrib><contrib contrib-type="author"><name><surname>Hwang</surname><given-names>Helena</given-names></name><xref rid="A76" ref-type="aff">76</xref></contrib><contrib contrib-type="author"><name><surname>Eccles</surname><given-names>Diana M.</given-names></name><xref rid="A77" ref-type="aff">77</xref></contrib><contrib contrib-type="author"><name><surname>Garcia-Closas</surname><given-names>Montserrat</given-names></name><xref rid="A78" ref-type="aff">78</xref></contrib><contrib contrib-type="author"><name><surname>Figueroa</surname><given-names>Jonine D.</given-names></name><xref rid="A79" ref-type="aff">79</xref></contrib><contrib contrib-type="author"><name><surname>Sherman</surname><given-names>Mark E.</given-names></name><xref rid="A79" ref-type="aff">79</xref></contrib><contrib contrib-type="author"><name><surname>Lissowska</surname><given-names>Jolanta</given-names></name><xref rid="A80" ref-type="aff">80</xref></contrib><contrib contrib-type="author"><name><surname>Devilee</surname><given-names>Peter</given-names></name><xref rid="A81" ref-type="aff">81</xref></contrib><contrib contrib-type="author"><name><surname>Seynaeve</surname><given-names>Caroline</given-names></name><xref rid="A82" ref-type="aff">82</xref></contrib><contrib contrib-type="author"><name><surname>Tollenaar</surname><given-names>R.A.E.M.</given-names></name><xref rid="A83" ref-type="aff">83</xref></contrib><contrib contrib-type="author"><name><surname>Hooning</surname><given-names>Maartje J.</given-names></name><xref rid="A82" ref-type="aff">82</xref></contrib><contrib contrib-type="author"><name><surname>Andrulis</surname><given-names>Irene L.</given-names></name><xref rid="A84" ref-type="aff">84</xref></contrib><contrib contrib-type="author"><name><surname>Knight</surname><given-names>Julia A.</given-names></name><xref rid="A85" ref-type="aff">85</xref></contrib><contrib contrib-type="author"><name><surname>Glendon</surname><given-names>Gord</given-names></name><xref rid="A86" ref-type="aff">86</xref></contrib><contrib contrib-type="author"><name><surname>Mulligan</surname><given-names>Anna Marie</given-names></name><xref rid="A87" ref-type="aff">87</xref></contrib><contrib contrib-type="author"><name><surname>Winqvist</surname><given-names>Robert</given-names></name><xref rid="A88" ref-type="aff">88</xref></contrib><contrib contrib-type="author"><name><surname>Pylkäs</surname><given-names>Katri</given-names></name><xref rid="A88" ref-type="aff">88</xref></contrib><contrib contrib-type="author"><name><surname>Jukkola-Vuorinen</surname><given-names>Arja</given-names></name><xref rid="A89" ref-type="aff">89</xref></contrib><contrib contrib-type="author"><name><surname>Grip</surname><given-names>Mervi</given-names></name><xref rid="A90" ref-type="aff">90</xref></contrib><contrib contrib-type="author"><name><surname>John</surname><given-names>Esther M.</given-names></name><xref rid="A63" ref-type="aff">63</xref></contrib><contrib contrib-type="author"><name><surname>Miron</surname><given-names>Alexander</given-names></name><xref rid="A27" ref-type="aff">27</xref></contrib><contrib contrib-type="author"><name><surname>Alnæs</surname><given-names>Grethe Grenaker</given-names></name><xref rid="A91" ref-type="aff">91</xref><xref rid="A92" ref-type="aff">92</xref></contrib><contrib contrib-type="author"><name><surname>Kristensen</surname><given-names>Vessela</given-names></name><xref rid="A91" ref-type="aff">91</xref><xref rid="A92" ref-type="aff">92</xref></contrib><contrib contrib-type="author"><name><surname>Børresen-Dale</surname><given-names>Anne-Lise</given-names></name><xref rid="A93" ref-type="aff">93</xref></contrib><contrib contrib-type="author"><name><surname>Giles</surname><given-names>Graham G.</given-names></name><xref rid="A94" ref-type="aff">94</xref><xref rid="A95" ref-type="aff">95</xref></contrib><contrib contrib-type="author"><name><surname>Baglietto</surname><given-names>Laura</given-names></name><xref rid="A94" ref-type="aff">94</xref><xref rid="A95" ref-type="aff">95</xref></contrib><contrib contrib-type="author"><name><surname>McLean</surname><given-names>Catriona A</given-names></name><xref rid="A96" ref-type="aff">96</xref></contrib><contrib contrib-type="author"><name><surname>Severi</surname><given-names>Gianluca</given-names></name><xref rid="A94" ref-type="aff">94</xref><xref rid="A95" ref-type="aff">95</xref></contrib><contrib contrib-type="author"><name><surname>Kosel</surname><given-names>Matthew L.</given-names></name><xref rid="A1" ref-type="aff">1</xref></contrib><contrib contrib-type="author"><name><surname>Pankratz</surname><given-names>V.S.</given-names></name><xref rid="A1" ref-type="aff">1</xref></contrib><contrib contrib-type="author"><name><surname>Slager</surname><given-names>Susan</given-names></name><xref rid="A1" ref-type="aff">1</xref></contrib><contrib contrib-type="author"><name><surname>Olson</surname><given-names>Janet E.</given-names></name><xref rid="A1" ref-type="aff">1</xref></contrib><contrib contrib-type="author"><name><surname>Radice</surname><given-names>Paolo</given-names></name><xref rid="A97" ref-type="aff">97</xref><xref rid="A98" ref-type="aff">98</xref></contrib><contrib contrib-type="author"><name><surname>Peterlongo</surname><given-names>Paolo</given-names></name><xref rid="A97" ref-type="aff">97</xref><xref rid="A98" ref-type="aff">98</xref></contrib><contrib contrib-type="author"><name><surname>Manoukian</surname><given-names>Siranoush</given-names></name><xref rid="A99" ref-type="aff">99</xref></contrib><contrib contrib-type="author"><name><surname>Barile</surname><given-names>Monica</given-names></name><xref rid="A100" ref-type="aff">100</xref></contrib><contrib contrib-type="author"><name><surname>Lambrechts</surname><given-names>Diether</given-names></name><xref rid="A101" ref-type="aff">101</xref><xref rid="A102" ref-type="aff">102</xref></contrib><contrib contrib-type="author"><name><surname>Hatse</surname><given-names>Sigrid</given-names></name><xref rid="A103" ref-type="aff">103</xref></contrib><contrib contrib-type="author"><name><surname>Dieudonne</surname><given-names>Anne-Sophie</given-names></name><xref rid="A103" ref-type="aff">103</xref></contrib><contrib contrib-type="author"><name><surname>Christiaens</surname><given-names>Marie-Rose</given-names></name><xref rid="A103" ref-type="aff">103</xref></contrib><contrib contrib-type="author"><name><surname>Chenevix-Trench</surname><given-names>Georgia</given-names></name><xref rid="A104" ref-type="aff">104</xref></contrib><contrib contrib-type="author"><collab>on behalf of kConFab Investigators</collab><xref rid="A105" ref-type="aff">105</xref></contrib><contrib contrib-type="author"><collab>and the AOCS Group</collab><xref rid="A104" ref-type="aff">104</xref><xref rid="A105" ref-type="aff">105</xref></contrib><contrib contrib-type="author"><name><surname>Beesley</surname><given-names>Jonathan</given-names></name><xref rid="A104" ref-type="aff">104</xref></contrib><contrib contrib-type="author"><name><surname>Chen</surname><given-names>Xiaoqing</given-names></name><xref rid="A104" ref-type="aff">104</xref></contrib><contrib contrib-type="author"><name><surname>Mannermaa</surname><given-names>Arto</given-names></name><xref rid="A106" ref-type="aff">106</xref></contrib><contrib contrib-type="author"><name><surname>Kosma</surname><given-names>Veli-Matti</given-names></name><xref rid="A106" ref-type="aff">106</xref></contrib><contrib contrib-type="author"><name><surname>Hartikainen</surname><given-names>Jaana M.</given-names></name><xref rid="A106" ref-type="aff">106</xref></contrib><contrib contrib-type="author"><name><surname>Soini</surname><given-names>Ylermi</given-names></name><xref rid="A106" ref-type="aff">106</xref></contrib><contrib contrib-type="author"><name><surname>Easton</surname><given-names>Douglas F.</given-names></name><xref rid="A68" ref-type="aff">68</xref><xref rid="A69" ref-type="aff">69</xref></contrib><contrib contrib-type="author"><name><surname>Couch</surname><given-names>Fergus J.</given-names></name><xref rid="A2" ref-type="aff">2</xref><xref rid="FN1" ref-type="author-notes">*</xref></contrib></contrib-group><aff id="A1"><label>1</label>Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota</aff><aff id="A2"><label>2</label>Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota</aff><aff id="A3"><label>3</label>Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden</aff><aff id="A4"><label>4</label>Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Biomedicum Helsinki, Helsinki, Finland</aff><aff id="A5"><label>5</label>Department of Clinical Genetics, Helsinki University Central Hospital, Helsinki, Finland</aff><aff id="A6"><label>6</label>Department of Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland</aff><aff id="A7"><label>7</label>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</aff><aff id="A8"><label>8</label>Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg, Germany</aff><aff id="A9"><label>9</label>Department of Pathology, University Hospital Heidelberg, Heidelberg, Germany</aff><aff id="A10"><label>10</label>Department of Obstetrics and Gynecology, University of Ulm, Ulm, Germany</aff><aff id="A11"><label>11</label>Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany</aff><aff id="A12"><label>12</label>University of Tubingen, Tubingen, Germany</aff><aff id="A13"><label>13</label>Department of Internal Medicine, Evangelische Kliniken Bonn gGmbH, Johanniter Krankenhaus, Bonn, Germany</aff><aff id="A14"><label>14</label>Institute of Pathology, Medical Faculty of the University of Bonn, Bonn, Germany</aff><aff id="A15"><label>15</label>Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany</aff><aff id="A16"><label>16</label>Institute for Prevention and Occupational Medicine of the German Social Accident Insurance (IPA), Bochum, Germany</aff><aff id="A17"><label>17</label>Division of Molecular Gyneco-Oncology, Department of Gynaecology and Obstetrics, Center of Molecular Medicine Cologne (CMMC), University Hospital of Cologne, Cologne, Germany</aff><aff id="A18"><label>18</label>Department for Obstetrica and Gynaecology, Dvision for Tumor Genetics, Klinikum rechts der Isar, Technische Universität, Munich, Germany</aff><aff id="A19"><label>19</label>Institute of Human Genetics, University of Heidelberg, Heidelberg, Germany</aff><aff id="A20"><label>20</label>Department of Obstetrics and Gynecology, University Hospital Heidelberg, Heidelberg, Germany</aff><aff id="A21"><label>21</label>Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany</aff><aff id="A22"><label>22</label>Department of Pathology & Laboratory Medicine, University of Kansas Medical Center, Kansas City, USA</aff><aff id="A23"><label>23</label>Biosample Repository, Fox Chase Cancer Center, Philadelphia, USA</aff><aff id="A24"><label>24</label>Division of Hematology and Oncology, University of Kansas Medical Center, Kansas City, USA</aff><aff id="A25"><label>25</label>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany</aff><aff id="A26"><label>26</label>Saarland Cancer Registry, Saarbrücken, Germany</aff><aff id="A27"><label>27</label>Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, USA</aff><aff id="A28"><label>28</label>Molecular Diagnostics Laboratory, IRRP, National Centre for Scientific Research ‘Demokritos’, Athens, Greece</aff><aff id="A29"><label>29</label>Department of Medical Oncology, “Papageorgiou” Hospital, Ring Road, Aristotle University of Thessaloniki School of Medicine, Thessaloniki, Greece</aff><aff id="A30"><label>30</label>First Department of Medicine, University of Athens, Medical School, Athens, Greece</aff><aff id="A31"><label>31</label>Against Breast Cancer Research Unit, School of Life Sciences, University of Westminster, London, UK</aff><aff id="A32"><label>32</label>Genetic & Molecular Epidemiology Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain</aff><aff id="A33"><label>33</label>Human Genetics Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain</aff><aff id="A34"><label>34</label>Servicio de Oncología Médica, Hospital Universitario La Paz, Madrid, Spain</aff><aff id="A35"><label>35</label>Servicio de Cirugía General y Especialidades, Hospital Monte Naranco, Oviedo, Spain</aff><aff id="A36"><label>36</label>Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark</aff><aff id="A37"><label>37</label>The Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark</aff><aff id="A38"><label>38</label>Department of Breast Surgery, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark</aff><aff id="A39"><label>39</label>Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer, Villejuif, France</aff><aff id="A40"><label>40</label>University Paris-Sud, UMRS1018 Villejuif, France</aff><aff id="A41"><label>41</label>Molecular Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany</aff><aff id="A42"><label>42</label>National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany</aff><aff id="A43"><label>43</label>National Institute for Health Research (NIHR) Comprehensive Biomedical Research Centre, Guy’s & St. Thomas’ NHS Foundation Trust in partnership with King’s College London and King’s College Hospital NHS Foundation Trus, London, UK</aff><aff id="A44"><label>44</label>Welcome Trust Centre for Human Genetics and Oxford Biomedical Research Centre, University of Oxford, Oxford, UK</aff><aff id="A45"><label>45</label>NUIG Department of Surgery, Clinical Science Institute, University Hospital Galway, Galway, Ireland</aff><aff id="A46"><label>46</label>Department of Nion-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK</aff><aff id="A47"><label>47</label>Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK</aff><aff id="A48"><label>48</label>Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK</aff><aff id="A49"><label>49</label>University of California at Los Angeles, David Geffen School of Medicine, Department of Medicine, Division of Hematology and Oncology, Los Angeles, USA</aff><aff id="A50"><label>50</label>University Breast Center Franconia, Department of Gynecology and Obstetrics, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center, Erlangen-Nuremberg, Germany</aff><aff id="A51"><label>51</label>Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen-Nuremberg, Germany</aff><aff id="A52"><label>52</label>Institute of Human Genetics, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen-Nuremberg, Germany</aff><aff id="A53"><label>53</label>Health Sciences Research Institute, Warwick Medical School, Warwick University, Coventry, UK</aff><aff id="A54"><label>54</label>Department of Surgery, Medical school, Prince Songkla University, Songkla, Thailand</aff><aff id="A55"><label>55</label>Department of Pediatrics, Medical school, Khon Kaen University, Khon Kaen, Thailand</aff><aff id="A56"><label>56</label>Netherlands Cancer Institute, Amsterdam, Netherlands</aff><aff id="A57"><label>57</label>Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia</aff><aff id="A58"><label>58</label>Department of Pathology, The University of Melbourne, Melbourne, Australia</aff><aff id="A59"><label>59</label>Section of Epidemiology, Institute of Cancer Research., Sutton,, UK</aff><aff id="A60"><label>60</label>The Breakthrough Breast Cancer Research Centre, Institute of Cancer Research., London, UK</aff><aff id="A61"><label>61</label>Department of Epidemiology, School of Medicine, University of California Irvine, Irvine, CA</aff><aff id="A62"><label>62</label>Division of Cancer Etiology, Department of Population Sciences, Beckman Research Institute, City of Hope</aff><aff id="A63"><label>63</label>Department of Epidemiology, Cancer Prevention Institute of California, Fremont, CA</aff><aff id="A64"><label>64</label>Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan</aff><aff id="A65"><label>65</label>Department of Surgery, Tri-Service General Hospital, Taipei, Taiwan</aff><aff id="A66"><label>66</label>Molecular Genetics of Breast Cancer, Deutsches Krebsforschungsfzentrum (DKFZ), Heidelberg, Germany</aff><aff id="A67"><label>67</label>Institute of Pathology, Städtisches Klinikum Karlsruhe, Karlsruhe, Germany</aff><aff id="A68"><label>68</label>Women’s Clinic, Städtisches Klinikum Karlsruhe, Karlsruhe, Germany</aff><aff id="A69"><label>69</label>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK</aff><aff id="A70"><label>70</label>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK</aff><aff id="A71"><label>71</label>Dept of Oncology, Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, UK</aff><aff id="A72"><label>72</label>Department of Neuroscience, Faculty of Medicine, Dentistry & Health, University of Sheffield, Sheffield, UK</aff><aff id="A73"><label>73</label>Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</aff><aff id="A74"><label>74</label>Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, USA</aff><aff id="A75"><label>75</label>Department of Medicine, Roswell Park Cancer Institute, Buffalo, USA</aff><aff id="A76"><label>76</label>Department of Pathology, Roswell Park Cancer Institute, Buffalo, USA</aff><aff id="A77"><label>77</label>Faculty of Medicine, University of Southampton, Southampton, UK</aff><aff id="A78"><label>78</label>Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, UK</aff><aff id="A79"><label>79</label>Division of Cancer Epidemiology and Genetics, Hormonal and Reproductive Epidemiology Branch, NIH/NCI, Bethesda, USA</aff><aff id="A80"><label>80</label>Department of Cancer Epidemiology and Prevention, The M. Sklodowska-Curie Cancer Center and Institute of Oncology, Warsaw, Poland</aff><aff id="A81"><label>81</label>Department of Human Genetics & Department of Pathology, Leiden University Medical Center, Leiden, Netherlands</aff><aff id="A82"><label>82</label>Department of Medical Oncology, Erasmus Medical Center, Daniel den Hoed Cancer Center, Rotterdam, Netherlands</aff><aff id="A83"><label>83</label>Department of Surgical Oncology, Leiden University Medical Center, Leiden, Netherlands</aff><aff id="A84"><label>84</label>Departments of Molecular Genetics and Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada</aff><aff id="A85"><label>85</label>Dalla Lana School of Public Health, University of Toronto, Prosserman Centre for Health Research, Toronto, Canada</aff><aff id="A86"><label>86</label>Cancer Care Ontario, Princess Margaret Hospital, Toronto, Canada</aff><aff id="A87"><label>87</label>Department of Laboratory Medicine, Keenan Research Centre of the Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, Canada</aff><aff id="A88"><label>88</label>Department of Clinical Genetics, Institute of Clinical Medicine, Biocenter Oulu, University of Oulu, Oulu University Hospital, Oulu, Finland</aff><aff id="A89"><label>89</label>Department of Oncology, University of Oulu, Oulu University Hospital, Oulu, Finland</aff><aff id="A90"><label>90</label>Department of Surgery, University of Oulu, Oulu University Hospital, Oulu, Finland</aff><aff id="A91"><label>91</label>Institute for Clinical Epidemiology and Molecular Biology (EpiGen), Faculty of Medicine, University of Oslo, Oslo, Norway</aff><aff id="A92"><label>92</label>Group of Cancer Genome Variation Department of Genetics, Institute for Cancer Research, Oslo, Norway</aff><aff id="A93"><label>93</label>Department of Genetics, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo, Norway</aff><aff id="A94"><label>94</label>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Australia</aff><aff id="A95"><label>95</label>Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia</aff><aff id="A96"><label>96</label>The Alfred Hospital, Melbourne, Australia</aff><aff id="A97"><label>97</label>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale, Tumori (INT), Milan, Italy</aff><aff id="A98"><label>98</label>IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy</aff><aff id="A99"><label>99</label>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy</aff><aff id="A100"><label>100</label>Division of Cancer Prevention and Genetics, Chemoprevention, European Institute of Oncology, Milan, Italy</aff><aff id="A101"><label>101</label>Vesalius Research Center, VIB, Leuven, Belgium</aff><aff id="A102"><label>102</label>Vesalius Research Center, University of Leuven, Leuven, Belgium</aff><aff id="A103"><label>103</label>Multidisciplinary Breast Center, University Hospital Gasthuisberg, Leuven, Belgium</aff><aff id="A104"><label>104</label>Queensland Institute of Medical Research, Herston, Australia</aff><aff id="A105"><label>105</label>Peter MacCallum Cancer Centre, East Melbourne, Australia</aff><aff id="A106"><label>106</label>Institute of Clinical Medicine, Department of Pathology, University of Eastern Finland and Kuopio University Hospital, Biocenter Kuopio, Kuopio, Finland</aff><author-notes><corresp id="FN1"><label>*</label>Correspondence: Fergus J. Couch, Stabile 2-42, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. Tel: (507) 284-3623; Fax: (507) 538-1937; <email>couch.fergus@mayo.edu</email></corresp></author-notes><pub-date pub-type="nihms-submitted"><day>17</day><month>2</month><year>2012</year></pub-date><pub-date pub-type="epub"><day>13</day><month>2</month><year>2012</year></pub-date><pub-date pub-type="ppub"><day>1</day><month>4</month><year>2012</year></pub-date><pub-date pub-type="pmc-release"><day>1</day><month>10</month><year>2012</year></pub-date><volume>72</volume><issue>7</issue><fpage>1795</fpage><lpage>1803</lpage><abstract><p id="P1">The 19p13.1 breast cancer susceptibility locus is a modifier of breast cancer risk in BRCA1 mutation carriers and is also associated with risk of ovarian cancer. Here we investigated 19p13.1 variation and risk of breast cancer subtypes, defined by estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor-2 (HER2) status, using 48,869 breast cancer cases and 49,787 controls from the Breast Cancer Association Consortium (BCAC). Variants from 19p13.1 were not associated with breast cancer overall or with ER-positive breast cancer but were significantly associated with ER-negative breast cancer risk [rs8170 Odds Ratio (OR)=1.10, 95% Confidence Interval (CI) 1.05 – 1.15, p=3.49 × 10-5] and triple negative (TN) (ER, PR and HER2 negative) breast cancer [rs8170 OR=1.22, 95% CI 1.13 – 1.31, p=2.22 × 10-7]. However, rs8170 was no longer associated with ER-negative breast cancer risk when TN cases were excluded [OR=0.98, 95% CI 0.89 – 1.07, p=0.62]. In addition, a combined analysis of TN cases from BCAC and the Triple Negative Breast Cancer Consortium (TNBCC) (n=3,566) identified a genome-wide significant association between rs8170 and TN breast cancer risk [OR=1.25, 95% CI 1.18 – 1.33, p=3.31 × 10-13]. Thus, 19p13.1 is the first triple negative-specific breast cancer risk locus and the first locus specific to a histological subtype defined by ER, PR, and HER2 to be identified. These findings provide convincing evidence that genetic susceptibility to breast cancer varies by tumor subtype and that triple negative tumors and other subtypes likely arise through distinct etiologic pathways.</p></abstract><kwd-group><kwd>genetic susceptibility</kwd><kwd>association study</kwd><kwd>subtype</kwd><kwd>neoplasms</kwd><kwd>common variant</kwd></kwd-group><funding-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>U01 CA069638-14 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>R01 CA122340-05 || CA</award-id></award-group></funding-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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