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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Revised Definitions of Invasive Fungal Disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group</title><author><name sortKey="De Pauw, Ben" sort="De Pauw, Ben" uniqKey="De Pauw B" first="Ben" last="De Pauw">Ben De Pauw</name></author><author><name sortKey="Walsh, Thomas J" sort="Walsh, Thomas J" uniqKey="Walsh T" first="Thomas J." last="Walsh">Thomas J. Walsh</name></author><author><name sortKey="Donnelly, J Peter" sort="Donnelly, J Peter" uniqKey="Donnelly J" first="J. Peter" last="Donnelly">J. Peter Donnelly</name></author><author><name sortKey="Stevens, David A" sort="Stevens, David A" uniqKey="Stevens D" first="David A." last="Stevens">David A. Stevens</name></author><author><name sortKey="Edwards, John E" sort="Edwards, John E" uniqKey="Edwards J" first="John E." last="Edwards">John E. Edwards</name></author><author><name sortKey="Calandra, Thierry" sort="Calandra, Thierry" uniqKey="Calandra T" first="Thierry" last="Calandra">Thierry Calandra</name></author><author><name sortKey="Pappas, Peter G" sort="Pappas, Peter G" uniqKey="Pappas P" first="Peter G." last="Pappas">Peter G. Pappas</name></author><author><name sortKey="Maertens, Johan" sort="Maertens, Johan" uniqKey="Maertens J" first="Johan" last="Maertens">Johan Maertens</name></author><author><name sortKey="Lortholary, Olivier" sort="Lortholary, Olivier" uniqKey="Lortholary O" first="Olivier" last="Lortholary">Olivier Lortholary</name></author><author><name sortKey="Kauffman, Carol A" sort="Kauffman, Carol A" uniqKey="Kauffman C" first="Carol A." last="Kauffman">Carol A. Kauffman</name></author><author><name sortKey="Denning, David W" sort="Denning, David W" uniqKey="Denning D" first="David W." last="Denning">David W. Denning</name></author><author><name sortKey="Patterson, Thomas F" sort="Patterson, Thomas F" uniqKey="Patterson T" first="Thomas F." last="Patterson">Thomas F. Patterson</name></author><author><name sortKey="Maschmeyer, Georg" sort="Maschmeyer, Georg" uniqKey="Maschmeyer G" first="Georg" last="Maschmeyer">Georg Maschmeyer</name></author><author><name sortKey="Bille, Jacques" sort="Bille, Jacques" uniqKey="Bille J" first="Jacques" last="Bille">Jacques Bille</name></author><author><name sortKey="Dismukes, William E" sort="Dismukes, William E" uniqKey="Dismukes W" first="William E." last="Dismukes">William E. Dismukes</name></author><author><name sortKey="Herbrecht, Raoul" sort="Herbrecht, Raoul" uniqKey="Herbrecht R" first="Raoul" last="Herbrecht">Raoul Herbrecht</name></author><author><name sortKey="Hope, William W" sort="Hope, William W" uniqKey="Hope W" first="William W." last="Hope">William W. Hope</name></author><author><name sortKey="Kibbler, Christopher C" sort="Kibbler, Christopher C" uniqKey="Kibbler C" first="Christopher C." last="Kibbler">Christopher C. Kibbler</name></author><author><name sortKey="Kullberg, Bart Jan" sort="Kullberg, Bart Jan" uniqKey="Kullberg B" first="Bart Jan" last="Kullberg">Bart Jan Kullberg</name></author><author><name sortKey="Marr, Kieren A" sort="Marr, Kieren A" uniqKey="Marr K" first="Kieren A." last="Marr">Kieren A. Marr</name></author><author><name sortKey="Mu Oz, Patricia" sort="Mu Oz, Patricia" uniqKey="Mu Oz P" first="Patricia" last="Mu Oz">Patricia Mu Oz</name></author><author><name sortKey="Odds, Frank C" sort="Odds, Frank C" uniqKey="Odds F" first="Frank C." last="Odds">Frank C. Odds</name></author><author><name sortKey="Perfect, John R" sort="Perfect, John R" uniqKey="Perfect J" first="John R." last="Perfect">John R. Perfect</name></author><author><name sortKey="Restrepo, Angela" sort="Restrepo, Angela" uniqKey="Restrepo A" first="Angela" last="Restrepo">Angela Restrepo</name></author><author><name sortKey="Ruhnke, Markus" sort="Ruhnke, Markus" uniqKey="Ruhnke M" first="Markus" last="Ruhnke">Markus Ruhnke</name></author><author><name sortKey="Segal, Brahm H" sort="Segal, Brahm H" uniqKey="Segal B" first="Brahm H." last="Segal">Brahm H. Segal</name></author><author><name sortKey="Sobel, Jack D" sort="Sobel, Jack D" uniqKey="Sobel J" first="Jack D." last="Sobel">Jack D. Sobel</name></author><author><name sortKey="Sorrell, Tania C" sort="Sorrell, Tania C" uniqKey="Sorrell T" first="Tania C." last="Sorrell">Tania C. Sorrell</name></author><author><name sortKey="Viscoli, Claudio" sort="Viscoli, Claudio" uniqKey="Viscoli C" first="Claudio" last="Viscoli">Claudio Viscoli</name></author><author><name sortKey="Wingard, John R" sort="Wingard, John R" uniqKey="Wingard J" first="John R." last="Wingard">John R. Wingard</name></author><author><name sortKey="Zaoutis, Theoklis" sort="Zaoutis, Theoklis" uniqKey="Zaoutis T" first="Theoklis" last="Zaoutis">Theoklis Zaoutis</name></author><author><name sortKey="Bennett, John E" sort="Bennett, John E" uniqKey="Bennett J" first="John E." last="Bennett">John E. Bennett</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">18462102</idno><idno type="pmc">2671227</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671227</idno><idno type="RBID">PMC:2671227</idno><idno type="doi">10.1086/588660</idno><date when="2008">2008</date><idno type="wicri:Area/Pmc/Corpus">001476</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001476</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Revised Definitions of Invasive Fungal Disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group</title><author><name sortKey="De Pauw, Ben" sort="De Pauw, Ben" uniqKey="De Pauw B" first="Ben" last="De Pauw">Ben De Pauw</name></author><author><name sortKey="Walsh, Thomas J" sort="Walsh, Thomas J" uniqKey="Walsh T" first="Thomas J." last="Walsh">Thomas J. Walsh</name></author><author><name sortKey="Donnelly, J Peter" sort="Donnelly, J Peter" uniqKey="Donnelly J" first="J. Peter" last="Donnelly">J. Peter Donnelly</name></author><author><name sortKey="Stevens, David A" sort="Stevens, David A" uniqKey="Stevens D" first="David A." last="Stevens">David A. Stevens</name></author><author><name sortKey="Edwards, John E" sort="Edwards, John E" uniqKey="Edwards J" first="John E." last="Edwards">John E. Edwards</name></author><author><name sortKey="Calandra, Thierry" sort="Calandra, Thierry" uniqKey="Calandra T" first="Thierry" last="Calandra">Thierry Calandra</name></author><author><name sortKey="Pappas, Peter G" sort="Pappas, Peter G" uniqKey="Pappas P" first="Peter G." last="Pappas">Peter G. Pappas</name></author><author><name sortKey="Maertens, Johan" sort="Maertens, Johan" uniqKey="Maertens J" first="Johan" last="Maertens">Johan Maertens</name></author><author><name sortKey="Lortholary, Olivier" sort="Lortholary, Olivier" uniqKey="Lortholary O" first="Olivier" last="Lortholary">Olivier Lortholary</name></author><author><name sortKey="Kauffman, Carol A" sort="Kauffman, Carol A" uniqKey="Kauffman C" first="Carol A." last="Kauffman">Carol A. Kauffman</name></author><author><name sortKey="Denning, David W" sort="Denning, David W" uniqKey="Denning D" first="David W." last="Denning">David W. Denning</name></author><author><name sortKey="Patterson, Thomas F" sort="Patterson, Thomas F" uniqKey="Patterson T" first="Thomas F." last="Patterson">Thomas F. Patterson</name></author><author><name sortKey="Maschmeyer, Georg" sort="Maschmeyer, Georg" uniqKey="Maschmeyer G" first="Georg" last="Maschmeyer">Georg Maschmeyer</name></author><author><name sortKey="Bille, Jacques" sort="Bille, Jacques" uniqKey="Bille J" first="Jacques" last="Bille">Jacques Bille</name></author><author><name sortKey="Dismukes, William E" sort="Dismukes, William E" uniqKey="Dismukes W" first="William E." last="Dismukes">William E. Dismukes</name></author><author><name sortKey="Herbrecht, Raoul" sort="Herbrecht, Raoul" uniqKey="Herbrecht R" first="Raoul" last="Herbrecht">Raoul Herbrecht</name></author><author><name sortKey="Hope, William W" sort="Hope, William W" uniqKey="Hope W" first="William W." last="Hope">William W. Hope</name></author><author><name sortKey="Kibbler, Christopher C" sort="Kibbler, Christopher C" uniqKey="Kibbler C" first="Christopher C." last="Kibbler">Christopher C. Kibbler</name></author><author><name sortKey="Kullberg, Bart Jan" sort="Kullberg, Bart Jan" uniqKey="Kullberg B" first="Bart Jan" last="Kullberg">Bart Jan Kullberg</name></author><author><name sortKey="Marr, Kieren A" sort="Marr, Kieren A" uniqKey="Marr K" first="Kieren A." last="Marr">Kieren A. Marr</name></author><author><name sortKey="Mu Oz, Patricia" sort="Mu Oz, Patricia" uniqKey="Mu Oz P" first="Patricia" last="Mu Oz">Patricia Mu Oz</name></author><author><name sortKey="Odds, Frank C" sort="Odds, Frank C" uniqKey="Odds F" first="Frank C." last="Odds">Frank C. Odds</name></author><author><name sortKey="Perfect, John R" sort="Perfect, John R" uniqKey="Perfect J" first="John R." last="Perfect">John R. Perfect</name></author><author><name sortKey="Restrepo, Angela" sort="Restrepo, Angela" uniqKey="Restrepo A" first="Angela" last="Restrepo">Angela Restrepo</name></author><author><name sortKey="Ruhnke, Markus" sort="Ruhnke, Markus" uniqKey="Ruhnke M" first="Markus" last="Ruhnke">Markus Ruhnke</name></author><author><name sortKey="Segal, Brahm H" sort="Segal, Brahm H" uniqKey="Segal B" first="Brahm H." last="Segal">Brahm H. Segal</name></author><author><name sortKey="Sobel, Jack D" sort="Sobel, Jack D" uniqKey="Sobel J" first="Jack D." last="Sobel">Jack D. Sobel</name></author><author><name sortKey="Sorrell, Tania C" sort="Sorrell, Tania C" uniqKey="Sorrell T" first="Tania C." last="Sorrell">Tania C. Sorrell</name></author><author><name sortKey="Viscoli, Claudio" sort="Viscoli, Claudio" uniqKey="Viscoli C" first="Claudio" last="Viscoli">Claudio Viscoli</name></author><author><name sortKey="Wingard, John R" sort="Wingard, John R" uniqKey="Wingard J" first="John R." last="Wingard">John R. Wingard</name></author><author><name sortKey="Zaoutis, Theoklis" sort="Zaoutis, Theoklis" uniqKey="Zaoutis T" first="Theoklis" last="Zaoutis">Theoklis Zaoutis</name></author><author><name sortKey="Bennett, John E" sort="Bennett, John E" uniqKey="Bennett J" first="John E." last="Bennett">John E. Bennett</name></author></analytic><series><title level="j">Clinical infectious diseases : an official publication of the Infectious Diseases Society of America</title><idno type="ISSN">1058-4838</idno><idno type="eISSN">1537-6591</idno><imprint><date when="2008">2008</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="S1"><title>Background</title><p id="P1">Invasive fungal diseases are important causes of morbidity and mortality. Clarity and uniformity in defining these infections are important factors in improving the quality of clinical studies. A standard set of definitions strengthens the consistency and reproducibility of such studies.</p></sec><sec sec-type="methods" id="S2"><title>Methods</title><p id="P2">After the introduction of the original European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group definitions, advances in diagnostic technology and the recognition of areas in need of improvement led to a revision of this document. The revision process started with a meeting of participants in 2003, to decide on the process and to draft the proposal. This was followed by several rounds of consultation until a final draft was approved in 2005. This was made available for 6 months to allow public comment, and then the manuscript was prepared and approved.</p></sec><sec id="S3"><title>Results</title><p id="P3">The revised definitions retain the original classifications of “proven,” “probable,” and “possible” invasive fungal disease, but the definition of “probable” has been expanded, whereas the scope of the category “possible” has been diminished. The category of proven invasive fungal disease can apply to any patient, regardless of whether the patient is immunocompromised, whereas the probable and possible categories are proposed for immunocompromised patients only.</p></sec><sec id="S4"><title>Conclusions</title><p id="P4">These revised definitions of invasive fungal disease are intended to advance clinical and epidemiological research and may serve as a useful model for defining other infections in high-risk patients.</p></sec></div></front></TEI><pmc article-type="research-article" xml:lang="EN"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">9203213</journal-id><journal-id journal-id-type="pubmed-jr-id">1135</journal-id><journal-id journal-id-type="nlm-ta">Clin Infect Dis</journal-id><journal-title>Clinical infectious diseases : an official publication of the Infectious Diseases Society of America</journal-title><issn pub-type="ppub">1058-4838</issn><issn pub-type="epub">1537-6591</issn></journal-meta><article-meta><article-id pub-id-type="pmid">18462102</article-id><article-id pub-id-type="pmc">2671227</article-id><article-id pub-id-type="doi">10.1086/588660</article-id><article-id pub-id-type="manuscript">NIHMS103083</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Revised Definitions of Invasive Fungal Disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>De Pauw</surname><given-names>Ben</given-names></name><xref rid="FN2" ref-type="author-notes">a</xref></contrib><contrib contrib-type="author"><name><surname>Walsh</surname><given-names>Thomas J.</given-names></name><xref rid="FN2" ref-type="author-notes">a</xref></contrib><contrib contrib-type="author"><name><surname>Donnelly</surname><given-names>J. Peter</given-names></name><xref rid="FN2" ref-type="author-notes">a</xref></contrib><contrib contrib-type="author"><name><surname>Stevens</surname><given-names>David A.</given-names></name></contrib><contrib contrib-type="author"><name><surname>Edwards</surname><given-names>John E.</given-names></name></contrib><contrib contrib-type="author"><name><surname>Calandra</surname><given-names>Thierry</given-names></name></contrib><contrib contrib-type="author"><name><surname>Pappas</surname><given-names>Peter G.</given-names></name></contrib><contrib contrib-type="author"><name><surname>Maertens</surname><given-names>Johan</given-names></name></contrib><contrib contrib-type="author"><name><surname>Lortholary</surname><given-names>Olivier</given-names></name></contrib><contrib contrib-type="author"><name><surname>Kauffman</surname><given-names>Carol A.</given-names></name></contrib><contrib contrib-type="author"><name><surname>Denning</surname><given-names>David W.</given-names></name></contrib><contrib contrib-type="author"><name><surname>Patterson</surname><given-names>Thomas F.</given-names></name></contrib><contrib contrib-type="author"><name><surname>Maschmeyer</surname><given-names>Georg</given-names></name></contrib><contrib contrib-type="author"><name><surname>Bille</surname><given-names>Jacques</given-names></name></contrib><contrib contrib-type="author"><name><surname>Dismukes</surname><given-names>William E.</given-names></name></contrib><contrib contrib-type="author"><name><surname>Herbrecht</surname><given-names>Raoul</given-names></name></contrib><contrib contrib-type="author"><name><surname>Hope</surname><given-names>William W.</given-names></name></contrib><contrib contrib-type="author"><name><surname>Kibbler</surname><given-names>Christopher C.</given-names></name></contrib><contrib contrib-type="author"><name><surname>Kullberg</surname><given-names>Bart Jan</given-names></name></contrib><contrib contrib-type="author"><name><surname>Marr</surname><given-names>Kieren A.</given-names></name></contrib><contrib contrib-type="author"><name><surname>Muñoz</surname><given-names>Patricia</given-names></name></contrib><contrib contrib-type="author"><name><surname>Odds</surname><given-names>Frank C.</given-names></name></contrib><contrib contrib-type="author"><name><surname>Perfect</surname><given-names>John R.</given-names></name></contrib><contrib contrib-type="author"><name><surname>Restrepo</surname><given-names>Angela</given-names></name></contrib><contrib contrib-type="author"><name><surname>Ruhnke</surname><given-names>Markus</given-names></name></contrib><contrib contrib-type="author"><name><surname>Segal</surname><given-names>Brahm H.</given-names></name></contrib><contrib contrib-type="author"><name><surname>Sobel</surname><given-names>Jack D.</given-names></name></contrib><contrib contrib-type="author"><name><surname>Sorrell</surname><given-names>Tania C.</given-names></name></contrib><contrib contrib-type="author"><name><surname>Viscoli</surname><given-names>Claudio</given-names></name></contrib><contrib contrib-type="author"><name><surname>Wingard</surname><given-names>John R.</given-names></name></contrib><contrib contrib-type="author"><name><surname>Zaoutis</surname><given-names>Theoklis</given-names></name></contrib><contrib contrib-type="author"><name><surname>Bennett</surname><given-names>John E.</given-names></name></contrib><aff id="A1">Departments of Blood Transfusion Service and Transplant Immunology (B.d.P.), Hematology (J.P.D.), and Internal Medicine (B.J.K.), Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands; Immunocompromised Host Section, Pediatric Oncology Branch, National Cancer Institute (T.J.W.), and Clinical Mycology Section, Laboratory of Clinical Investigation, National Institute of Allergy and Infectious Diseases (J.E.B.), National Institutes of Health, Bethesda, Maryland; Santa Clara Valley Medical Center, San Jose (D.A.S.), Stanford University, Palo Alto (D.A.S.), and Los Angeles Biomedical Research Institute at Harbor–University of California Los Angeles Medical Center, Torrance (J.E.E.), California; Division of Infectious Diseases, Department of Medicine, University of Alabama, Birmingham (P.G.P., W.E.D.); Infectious Diseases Division, Department of Internal Medicine, Ann Arbor Veterans Affairs Healthcare System, University of Michigan Medical School, Ann Arbor (C.A.K.); The University of Texas Health Science Center at San Antonio, Department of Medicine and Infectious Diseases, San Antonio (T.F.P.); Division of Infectious Diseases, Oregon Health and Science University, Portland (K.A.M.); Division of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, North Carolina (J.R.P.); Department of Medicine, State University of New York at Buffalo, Roswell Park Cancer Institute, Buffalo (B.H.S.); Department of Medicine, Wayne State University School of Medicine, Detroit, Michigan (J.D.S.); Division of Hematology and Oncology, University of Florida Shands Cancer Center, Gainesville (J.R.W.); Pediatric Infectious Diseases, The Children's Hospital of Philadelphia, The Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia (T.Z.); Infectious Diseases Service, Department of Internal Medicine (T.C.), and Clinical Microbiology Laboratory (J.B.), Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland; Department of Hematology, University Hospital Gasthuisberg, Leuven, Belgium (J.M.); Service des Maladies Infectieuses et Tropicales, Hopital Necker, Paris (O.L.), and Hematology and Oncology Department, University Hospital of Strasbourg, Strasbourg (R.H.), France; Education and Research Centre, Wythenshawe Hospital (D.W.D.), and University of Manchester (W.W.H.), Manchester, Department of Medical Microbiology, Royal Free Hospital, London (C.C.K.), and Aberdeen Fungal Group, Institute of Medical Sciences, University of Aberdeen, Aberdeen (F.C.O.), United Kingdom; Medizinische Klinik, Abteilung Hamatologie und Onkologie, Klinikum Ernst von Bergmann, Potsdam (G.M.), and Charité Universitätsmedizin, Campus Charité Mitte, Medizinische Klinik und Poliklinik II, Berlin (M.R.), Germany; Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Maranon, University of Madrid, Madrid, Spain (P.M.); Corporacion para Investigaciones Biologicas, Carrera, Medellin, Colombia (A.R.); Centre for Infectious Diseases and Microbiology and National Health and Medical Research Council's Centre for Clinical Research Excellence in Infections, Bioethics and Haematological Malignancies, Westmead Millennium Institute, University of Sydney, Sydney, Australia (T.C.S.); and Infectious Diseases, University of Genova and San Martino University Hospital, Genoa, Italy (C.V.)</aff></contrib-group><author-notes><corresp id="FN1">Reprints or correspondence: J. Peter Donnelly, Dept. of Haematology, Radboud University Nijmegen Medical Centre, Geert Grooteplein Zuid 8, 6525 GA Nijmegen, The Netherlands (<email>p.donnelly@usa.net</email>)</corresp><fn id="FN2"><label>a</label><p>B.d.P. and T.J.W. served as cochairs and J.P.D. served as secretary for the EORTC/MSG Consensus Group.</p></fn></author-notes><pub-date pub-type="nihms-submitted"><day>18</day><month>3</month><year>2009</year></pub-date><pub-date pub-type="ppub"><day>15</day><month>6</month><year>2008</year></pub-date><pub-date pub-type="pmc-release"><day>21</day><month>4</month><year>2009</year></pub-date><volume>46</volume><issue>12</issue><fpage>1813</fpage><lpage>1821</lpage><abstract><sec id="S1"><title>Background</title><p id="P1">Invasive fungal diseases are important causes of morbidity and mortality. Clarity and uniformity in defining these infections are important factors in improving the quality of clinical studies. A standard set of definitions strengthens the consistency and reproducibility of such studies.</p></sec><sec sec-type="methods" id="S2"><title>Methods</title><p id="P2">After the introduction of the original European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group definitions, advances in diagnostic technology and the recognition of areas in need of improvement led to a revision of this document. The revision process started with a meeting of participants in 2003, to decide on the process and to draft the proposal. This was followed by several rounds of consultation until a final draft was approved in 2005. This was made available for 6 months to allow public comment, and then the manuscript was prepared and approved.</p></sec><sec id="S3"><title>Results</title><p id="P3">The revised definitions retain the original classifications of “proven,” “probable,” and “possible” invasive fungal disease, but the definition of “probable” has been expanded, whereas the scope of the category “possible” has been diminished. The category of proven invasive fungal disease can apply to any patient, regardless of whether the patient is immunocompromised, whereas the probable and possible categories are proposed for immunocompromised patients only.</p></sec><sec id="S4"><title>Conclusions</title><p id="P4">These revised definitions of invasive fungal disease are intended to advance clinical and epidemiological research and may serve as a useful model for defining other infections in high-risk patients.</p></sec></abstract><contract-num rid="AI1">Z01 AI000654-16</contract-num><contract-sponsor id="AI1">National Institute of Allergy and Infectious Diseases Extramural Activities : NIAID</contract-sponsor></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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