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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Mental–physical co-morbidity and its relationship with disability: results from the World Mental Health Surveys</title><author><name sortKey="Scott, K M" sort="Scott, K M" uniqKey="Scott K" first="K. M." last="Scott">K. M. Scott</name><affiliation><nlm:aff id="A1">Department of Psychological Medicine, Otago University, Wellington, New Zealand</nlm:aff></affiliation></author><author><name sortKey="Von Korff, M" sort="Von Korff, M" uniqKey="Von Korff M" first="M." last="Von Korff">M. Von Korff</name><affiliation><nlm:aff id="A2">Center for Health Studies, Group Health Cooperative of Puget Sound, Seattle, WA, USA</nlm:aff></affiliation></author><author><name sortKey="Alonso, J" sort="Alonso, J" uniqKey="Alonso J" first="J." last="Alonso">J. Alonso</name><affiliation><nlm:aff id="A3">Health Services Research Unit, Institute of Municipal d’Investigacio Medica (IMIM), Barcelona, Spain</nlm:aff></affiliation></author><author><name sortKey="Angermeyer, M C" sort="Angermeyer, M C" uniqKey="Angermeyer M" first="M. C." last="Angermeyer">M. C. Angermeyer</name><affiliation><nlm:aff id="A4">Department of Psychiatry, University of Leipzig, Germany</nlm:aff></affiliation></author><author><name sortKey="Bromet, E" sort="Bromet, E" uniqKey="Bromet E" first="E." last="Bromet">E. Bromet</name><affiliation><nlm:aff id="A5">SUNY Stony Brook, Stony Brook, New York, USA</nlm:aff></affiliation></author><author><name sortKey="Fayyad, J" sort="Fayyad, J" uniqKey="Fayyad J" first="J." last="Fayyad">J. Fayyad</name><affiliation><nlm:aff id="A6">Institute for Development, Research, Advocacy and Applied Care (IDRAAC), Beirut, Lebanon</nlm:aff></affiliation></author><author><name sortKey="De Girolamo, G" sort="De Girolamo, G" uniqKey="De Girolamo G" first="G." last="De Girolamo">G. De Girolamo</name><affiliation><nlm:aff id="A7">Department of Mental Health, AUSL di Bologna, Italy</nlm:aff></affiliation></author><author><name sortKey="Demyttenaere, K" sort="Demyttenaere, K" uniqKey="Demyttenaere K" first="K." last="Demyttenaere">K. Demyttenaere</name><affiliation><nlm:aff id="A8">Department of Neurosciences and Psychiatry, University Hospital, Gasthuisberg, Leuven, Belgium</nlm:aff></affiliation></author><author><name sortKey="Gasquet, I" sort="Gasquet, I" uniqKey="Gasquet I" first="I." last="Gasquet">I. Gasquet</name><affiliation><nlm:aff id="A9">Hôpitaux de Paris, Paris, France</nlm:aff></affiliation></author><author><name sortKey="Gureje, O" sort="Gureje, O" uniqKey="Gureje O" first="O." last="Gureje">O. Gureje</name><affiliation><nlm:aff id="A10">Department of Psychiatry, University College Hospital, Ibadan, Nigeria</nlm:aff></affiliation></author><author><name sortKey="Haro, J M" sort="Haro, J M" uniqKey="Haro J" first="J. M." last="Haro">J. M. Haro</name><affiliation><nlm:aff id="A11">Sant Joan de Deu-SSM, Barcelona, Spain</nlm:aff></affiliation></author><author><name sortKey="He, Y" sort="He, Y" uniqKey="He Y" first="Y." last="He">Y. He</name><affiliation><nlm:aff id="A12">Shanghai Mental Health Centre, Shanghai, People’s Republic of China</nlm:aff></affiliation></author><author><name sortKey="Kessler, R C" sort="Kessler, R C" uniqKey="Kessler R" first="R. C." last="Kessler">R. C. Kessler</name><affiliation><nlm:aff id="A13">Department of Health Care Policy, Harvard Medical School, Boston, MA, USA</nlm:aff></affiliation></author><author><name sortKey="Levinson, D" sort="Levinson, D" uniqKey="Levinson D" first="D." last="Levinson">D. Levinson</name><affiliation><nlm:aff id="A14">Mental Health Services, Ministry of Health, Jerusalem, Israel</nlm:aff></affiliation></author><author><name sortKey="Medina Mora, M E" sort="Medina Mora, M E" uniqKey="Medina Mora M" first="M. E." last="Medina Mora">M. E. Medina Mora</name><affiliation><nlm:aff id="A15">National Institute of Psychiatry, Mexico City, Mexico</nlm:aff></affiliation></author><author><name sortKey="Oakley Browne, M" sort="Oakley Browne, M" uniqKey="Oakley Browne M" first="M." last="Oakley Browne">M. Oakley Browne</name><affiliation><nlm:aff id="A16">Department of Rural and Indigenous Health, School of Rural Health, Monash University, Australia</nlm:aff></affiliation></author><author><name sortKey="Ormel, J" sort="Ormel, J" uniqKey="Ormel J" first="J." last="Ormel">J. Ormel</name><affiliation><nlm:aff id="A17">Department of Psychiatry, University Medical Centre, Groningen, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Posada Villa, J" sort="Posada Villa, J" uniqKey="Posada Villa J" first="J." last="Posada-Villa">J. Posada-Villa</name><affiliation><nlm:aff id="A18">Development Rehabilitation System FSC, Saldarriaga Concha Foundation, Bogota, Colombia</nlm:aff></affiliation></author><author><name sortKey="Watanabe, M" sort="Watanabe, M" uniqKey="Watanabe M" first="M." last="Watanabe">M. Watanabe</name><affiliation><nlm:aff id="A19">Department of Public Health, Jichi Medical University, Tochigi, Japan</nlm:aff></affiliation></author><author><name sortKey="Williams, D" sort="Williams, D" uniqKey="Williams D" first="D." last="Williams">D. Williams</name><affiliation><nlm:aff id="A20">Harvard School of Public Health, Boston, MA, USA</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">18366819</idno><idno type="pmc">2637813</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637813</idno><idno type="RBID">PMC:2637813</idno><idno type="doi">10.1017/S0033291708003188</idno><date when="2008">2008</date><idno type="wicri:Area/Pmc/Corpus">001440</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001440</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Mental–physical co-morbidity and its relationship with disability: results from the World Mental Health Surveys</title><author><name sortKey="Scott, K M" sort="Scott, K M" uniqKey="Scott K" first="K. M." last="Scott">K. M. Scott</name><affiliation><nlm:aff id="A1">Department of Psychological Medicine, Otago University, Wellington, New Zealand</nlm:aff></affiliation></author><author><name sortKey="Von Korff, M" sort="Von Korff, M" uniqKey="Von Korff M" first="M." last="Von Korff">M. Von Korff</name><affiliation><nlm:aff id="A2">Center for Health Studies, Group Health Cooperative of Puget Sound, Seattle, WA, USA</nlm:aff></affiliation></author><author><name sortKey="Alonso, J" sort="Alonso, J" uniqKey="Alonso J" first="J." last="Alonso">J. Alonso</name><affiliation><nlm:aff id="A3">Health Services Research Unit, Institute of Municipal d’Investigacio Medica (IMIM), Barcelona, Spain</nlm:aff></affiliation></author><author><name sortKey="Angermeyer, M C" sort="Angermeyer, M C" uniqKey="Angermeyer M" first="M. C." last="Angermeyer">M. C. Angermeyer</name><affiliation><nlm:aff id="A4">Department of Psychiatry, University of Leipzig, Germany</nlm:aff></affiliation></author><author><name sortKey="Bromet, E" sort="Bromet, E" uniqKey="Bromet E" first="E." last="Bromet">E. Bromet</name><affiliation><nlm:aff id="A5">SUNY Stony Brook, Stony Brook, New York, USA</nlm:aff></affiliation></author><author><name sortKey="Fayyad, J" sort="Fayyad, J" uniqKey="Fayyad J" first="J." last="Fayyad">J. Fayyad</name><affiliation><nlm:aff id="A6">Institute for Development, Research, Advocacy and Applied Care (IDRAAC), Beirut, Lebanon</nlm:aff></affiliation></author><author><name sortKey="De Girolamo, G" sort="De Girolamo, G" uniqKey="De Girolamo G" first="G." last="De Girolamo">G. De Girolamo</name><affiliation><nlm:aff id="A7">Department of Mental Health, AUSL di Bologna, Italy</nlm:aff></affiliation></author><author><name sortKey="Demyttenaere, K" sort="Demyttenaere, K" uniqKey="Demyttenaere K" first="K." last="Demyttenaere">K. Demyttenaere</name><affiliation><nlm:aff id="A8">Department of Neurosciences and Psychiatry, University Hospital, Gasthuisberg, Leuven, Belgium</nlm:aff></affiliation></author><author><name sortKey="Gasquet, I" sort="Gasquet, I" uniqKey="Gasquet I" first="I." last="Gasquet">I. Gasquet</name><affiliation><nlm:aff id="A9">Hôpitaux de Paris, Paris, France</nlm:aff></affiliation></author><author><name sortKey="Gureje, O" sort="Gureje, O" uniqKey="Gureje O" first="O." last="Gureje">O. Gureje</name><affiliation><nlm:aff id="A10">Department of Psychiatry, University College Hospital, Ibadan, Nigeria</nlm:aff></affiliation></author><author><name sortKey="Haro, J M" sort="Haro, J M" uniqKey="Haro J" first="J. M." last="Haro">J. M. Haro</name><affiliation><nlm:aff id="A11">Sant Joan de Deu-SSM, Barcelona, Spain</nlm:aff></affiliation></author><author><name sortKey="He, Y" sort="He, Y" uniqKey="He Y" first="Y." last="He">Y. He</name><affiliation><nlm:aff id="A12">Shanghai Mental Health Centre, Shanghai, People’s Republic of China</nlm:aff></affiliation></author><author><name sortKey="Kessler, R C" sort="Kessler, R C" uniqKey="Kessler R" first="R. C." last="Kessler">R. C. Kessler</name><affiliation><nlm:aff id="A13">Department of Health Care Policy, Harvard Medical School, Boston, MA, USA</nlm:aff></affiliation></author><author><name sortKey="Levinson, D" sort="Levinson, D" uniqKey="Levinson D" first="D." last="Levinson">D. Levinson</name><affiliation><nlm:aff id="A14">Mental Health Services, Ministry of Health, Jerusalem, Israel</nlm:aff></affiliation></author><author><name sortKey="Medina Mora, M E" sort="Medina Mora, M E" uniqKey="Medina Mora M" first="M. E." last="Medina Mora">M. E. Medina Mora</name><affiliation><nlm:aff id="A15">National Institute of Psychiatry, Mexico City, Mexico</nlm:aff></affiliation></author><author><name sortKey="Oakley Browne, M" sort="Oakley Browne, M" uniqKey="Oakley Browne M" first="M." last="Oakley Browne">M. Oakley Browne</name><affiliation><nlm:aff id="A16">Department of Rural and Indigenous Health, School of Rural Health, Monash University, Australia</nlm:aff></affiliation></author><author><name sortKey="Ormel, J" sort="Ormel, J" uniqKey="Ormel J" first="J." last="Ormel">J. Ormel</name><affiliation><nlm:aff id="A17">Department of Psychiatry, University Medical Centre, Groningen, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Posada Villa, J" sort="Posada Villa, J" uniqKey="Posada Villa J" first="J." last="Posada-Villa">J. Posada-Villa</name><affiliation><nlm:aff id="A18">Development Rehabilitation System FSC, Saldarriaga Concha Foundation, Bogota, Colombia</nlm:aff></affiliation></author><author><name sortKey="Watanabe, M" sort="Watanabe, M" uniqKey="Watanabe M" first="M." last="Watanabe">M. Watanabe</name><affiliation><nlm:aff id="A19">Department of Public Health, Jichi Medical University, Tochigi, Japan</nlm:aff></affiliation></author><author><name sortKey="Williams, D" sort="Williams, D" uniqKey="Williams D" first="D." last="Williams">D. Williams</name><affiliation><nlm:aff id="A20">Harvard School of Public Health, Boston, MA, USA</nlm:aff></affiliation></author></analytic><series><title level="j">Psychological medicine</title><idno type="ISSN">0033-2917</idno><imprint><date when="2008">2008</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="S1"><title>Background</title><p id="P1">The relationship between mental and physical disorders is well established, but there is less consensus as to the nature of their joint association with disability, in part because additive and interactive models of co-morbidity have not always been clearly differentiated in prior research.</p></sec><sec sec-type="methods" id="S2"><title>Method</title><p id="P2">Eighteen general population surveys were carried out among adults as part of the World Mental Health (WMH) Survey Initiative (<italic>n</italic>=42 697). DSM-IV disorders were assessed using face-to-face interviews with the Composite International Diagnostic Interview (CIDI 3.0). Chronic physical conditions (arthritis, heart disease, respiratory disease, chronic back/neck pain, chronic headache, and diabetes) were ascertained using a standard checklist. Severe disability was defined as on or above the 90th percentile of the WMH version of the World Health Organization Disability Assessment Schedule (WHODAS-II).</p></sec><sec id="S3"><title>Results</title><p id="P3">The odds of severe disability among those with both mental disorder and each of the physical conditions (with the exception of heart disease) were significantly greater than the sum of the odds of the single conditions. The evidence for synergy was model dependent: it was observed in the additive interaction models but not in models assessing multiplicative interactions. Mental disorders were more likely to be associated with severe disability than were the chronic physical conditions.</p></sec><sec id="S4"><title>Conclusions</title><p id="P4">This first cross-national study of the joint effect of mental and physical conditions on the probability of severe disability finds that co-morbidity exerts modest synergistic effects. Clinicians need to accord both mental and physical conditions equal priority, in order for co-morbidity to be adequately managed and disability reduced.</p></sec></div></front></TEI><pmc article-type="research-article" xml:lang="EN"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">1254142</journal-id><journal-id journal-id-type="pubmed-jr-id">6777</journal-id><journal-id journal-id-type="nlm-ta">Psychol Med</journal-id><journal-title>Psychological medicine</journal-title><issn pub-type="ppub">0033-2917</issn></journal-meta><article-meta><article-id pub-id-type="pmid">18366819</article-id><article-id pub-id-type="pmc">2637813</article-id><article-id pub-id-type="doi">10.1017/S0033291708003188</article-id><article-id pub-id-type="manuscript">NIHMS89564</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Mental–physical co-morbidity and its relationship with disability: results from the World Mental Health Surveys</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Scott</surname><given-names>K. M.</given-names></name><xref rid="A1" ref-type="aff">1</xref><xref rid="FN1" ref-type="author-notes">*</xref></contrib><contrib contrib-type="author"><name><surname>Von Korff</surname><given-names>M.</given-names></name><xref rid="A2" ref-type="aff">2</xref></contrib><contrib contrib-type="author"><name><surname>Alonso</surname><given-names>J.</given-names></name><xref rid="A3" ref-type="aff">3</xref></contrib><contrib contrib-type="author"><name><surname>Angermeyer</surname><given-names>M. C.</given-names></name><xref rid="A4" ref-type="aff">4</xref></contrib><contrib contrib-type="author"><name><surname>Bromet</surname><given-names>E.</given-names></name><xref rid="A5" ref-type="aff">5</xref></contrib><contrib contrib-type="author"><name><surname>Fayyad</surname><given-names>J.</given-names></name><xref rid="A6" ref-type="aff">6</xref></contrib><contrib contrib-type="author"><name><surname>de Girolamo</surname><given-names>G.</given-names></name><xref rid="A7" ref-type="aff">7</xref></contrib><contrib contrib-type="author"><name><surname>Demyttenaere</surname><given-names>K.</given-names></name><xref rid="A8" ref-type="aff">8</xref></contrib><contrib contrib-type="author"><name><surname>Gasquet</surname><given-names>I.</given-names></name><xref rid="A9" ref-type="aff">9</xref></contrib><contrib contrib-type="author"><name><surname>Gureje</surname><given-names>O.</given-names></name><xref rid="A10" ref-type="aff">10</xref></contrib><contrib contrib-type="author"><name><surname>Haro</surname><given-names>J. M.</given-names></name><xref rid="A11" ref-type="aff">11</xref></contrib><contrib contrib-type="author"><name><surname>He</surname><given-names>Y.</given-names></name><xref rid="A12" ref-type="aff">12</xref></contrib><contrib contrib-type="author"><name><surname>Kessler</surname><given-names>R. C.</given-names></name><xref rid="A13" ref-type="aff">13</xref></contrib><contrib contrib-type="author"><name><surname>Levinson</surname><given-names>D.</given-names></name><xref rid="A14" ref-type="aff">14</xref></contrib><contrib contrib-type="author"><name><surname>Medina Mora</surname><given-names>M. E.</given-names></name><xref rid="A15" ref-type="aff">15</xref></contrib><contrib contrib-type="author"><name><surname>Oakley Browne</surname><given-names>M.</given-names></name><xref rid="A16" ref-type="aff">16</xref></contrib><contrib contrib-type="author"><name><surname>Ormel</surname><given-names>J.</given-names></name><xref rid="A17" ref-type="aff">17</xref></contrib><contrib contrib-type="author"><name><surname>Posada-Villa</surname><given-names>J.</given-names></name><xref rid="A18" ref-type="aff">18</xref></contrib><contrib contrib-type="author"><name><surname>Watanabe</surname><given-names>M.</given-names></name><xref rid="A19" ref-type="aff">19</xref></contrib><contrib contrib-type="author"><name><surname>Williams</surname><given-names>D.</given-names></name><xref rid="A20" ref-type="aff">20</xref></contrib></contrib-group><aff id="A1"><label>1</label>Department of Psychological Medicine, Otago University, Wellington, New Zealand</aff><aff id="A2"><label>2</label>Center for Health Studies, Group Health Cooperative of Puget Sound, Seattle, WA, USA</aff><aff id="A3"><label>3</label>Health Services Research Unit, Institute of Municipal d’Investigacio Medica (IMIM), Barcelona, Spain</aff><aff id="A4"><label>4</label>Department of Psychiatry, University of Leipzig, Germany</aff><aff id="A5"><label>5</label>SUNY Stony Brook, Stony Brook, New York, USA</aff><aff id="A6"><label>6</label>Institute for Development, Research, Advocacy and Applied Care (IDRAAC), Beirut, Lebanon</aff><aff id="A7"><label>7</label>Department of Mental Health, AUSL di Bologna, Italy</aff><aff id="A8"><label>8</label>Department of Neurosciences and Psychiatry, University Hospital, Gasthuisberg, Leuven, Belgium</aff><aff id="A9"><label>9</label>Hôpitaux de Paris, Paris, France</aff><aff id="A10"><label>10</label>Department of Psychiatry, University College Hospital, Ibadan, Nigeria</aff><aff id="A11"><label>11</label>Sant Joan de Deu-SSM, Barcelona, Spain</aff><aff id="A12"><label>12</label>Shanghai Mental Health Centre, Shanghai, People’s Republic of China</aff><aff id="A13"><label>13</label>Department of Health Care Policy, Harvard Medical School, Boston, MA, USA</aff><aff id="A14"><label>14</label>Mental Health Services, Ministry of Health, Jerusalem, Israel</aff><aff id="A15"><label>15</label>National Institute of Psychiatry, Mexico City, Mexico</aff><aff id="A16"><label>16</label>Department of Rural and Indigenous Health, School of Rural Health, Monash University, Australia</aff><aff id="A17"><label>17</label>Department of Psychiatry, University Medical Centre, Groningen, The Netherlands</aff><aff id="A18"><label>18</label>Development Rehabilitation System FSC, Saldarriaga Concha Foundation, Bogota, Colombia</aff><aff id="A19"><label>19</label>Department of Public Health, Jichi Medical University, Tochigi, Japan</aff><aff id="A20"><label>20</label>Harvard School of Public Health, Boston, MA, USA</aff><author-notes><corresp id="FN1"><label>*</label>Address for correspondence : K. M. Scott, Ph.D., Department of Psychological Medicine, Otago University, Wellington, PO Box 7343 Wellington South, New Zealand. (Email : <email>kate.scott@otago.ac.nz</email>)</corresp></author-notes><pub-date pub-type="nihms-submitted"><day>22</day><month>1</month><year>2009</year></pub-date><pub-date pub-type="epub"><day>26</day><month>3</month><year>2008</year></pub-date><pub-date pub-type="ppub"><month>1</month><year>2009</year></pub-date><pub-date pub-type="pmc-release"><day>1</day><month>1</month><year>2010</year></pub-date><volume>39</volume><issue>1</issue><fpage>33</fpage><lpage>43</lpage><abstract><sec id="S1"><title>Background</title><p id="P1">The relationship between mental and physical disorders is well established, but there is less consensus as to the nature of their joint association with disability, in part because additive and interactive models of co-morbidity have not always been clearly differentiated in prior research.</p></sec><sec sec-type="methods" id="S2"><title>Method</title><p id="P2">Eighteen general population surveys were carried out among adults as part of the World Mental Health (WMH) Survey Initiative (<italic>n</italic>=42 697). DSM-IV disorders were assessed using face-to-face interviews with the Composite International Diagnostic Interview (CIDI 3.0). Chronic physical conditions (arthritis, heart disease, respiratory disease, chronic back/neck pain, chronic headache, and diabetes) were ascertained using a standard checklist. Severe disability was defined as on or above the 90th percentile of the WMH version of the World Health Organization Disability Assessment Schedule (WHODAS-II).</p></sec><sec id="S3"><title>Results</title><p id="P3">The odds of severe disability among those with both mental disorder and each of the physical conditions (with the exception of heart disease) were significantly greater than the sum of the odds of the single conditions. The evidence for synergy was model dependent: it was observed in the additive interaction models but not in models assessing multiplicative interactions. Mental disorders were more likely to be associated with severe disability than were the chronic physical conditions.</p></sec><sec id="S4"><title>Conclusions</title><p id="P4">This first cross-national study of the joint effect of mental and physical conditions on the probability of severe disability finds that co-morbidity exerts modest synergistic effects. Clinicians need to accord both mental and physical conditions equal priority, in order for co-morbidity to be adequately managed and disability reduced.</p></sec></abstract><kwd-group><kwd>Co-morbidity</kwd><kwd>disability</kwd><kwd>interaction</kwd><kwd>mental</kwd><kwd>physical</kwd></kwd-group><contract-num rid="MH1">U13 MH066849-06</contract-num><contract-num rid="MH1">U01 MH060220-08</contract-num><contract-num rid="TW1">R03 TW006481-03</contract-num><contract-num rid="MH1">R01 MH073686-04</contract-num><contract-num rid="MH1">R01 MH070884-04</contract-num><contract-num rid="MH1">R01 MH061905-05</contract-num><contract-num rid="MH1">R01 MH059575-09</contract-num><contract-num rid="DA1">R01 DA016558-06</contract-num><contract-sponsor id="MH1">National Institute of Mental Health : NIMH</contract-sponsor><contract-sponsor id="TW1">Fogarty International Center : FIC</contract-sponsor><contract-sponsor id="DA1">National Institute on Drug Abuse : NIDA</contract-sponsor></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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