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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Electrophysiological studies of malaria parasite-infected erythrocytes: Current status</title><author><name sortKey="Staines, Henry M" sort="Staines, Henry M" uniqKey="Staines H" first="Henry M." last="Staines">Henry M. Staines</name><affiliation><nlm:aff id="A1">Centre for Infection, Division of Cellular and Molecular Medicine, St. George's, University of London, London SW17 0RE, UK</nlm:aff></affiliation></author><author><name sortKey="Alkhalil, Abdulnaser" sort="Alkhalil, Abdulnaser" uniqKey="Alkhalil A" first="Abdulnaser" last="Alkhalil">Abdulnaser Alkhalil</name><affiliation><nlm:aff id="A2">Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA</nlm:aff></affiliation></author><author><name sortKey="Allen, Richard J" sort="Allen, Richard J" uniqKey="Allen R" first="Richard J." last="Allen">Richard J. Allen</name><affiliation><nlm:aff id="A3">School of Biochemistry and Molecular Biology, The Australian National University, Canberra, ACT 0200, Australia</nlm:aff></affiliation></author><author><name sortKey="De Jonge, Hugo R" sort="De Jonge, Hugo R" uniqKey="De Jonge H" first="Hugo R." last="De Jonge">Hugo R. De Jonge</name><affiliation><nlm:aff id="A4">Department of Biochemistry, Erasmus University Medical Center, 3000 DR Rotterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Derbyshire, Elvira" sort="Derbyshire, Elvira" uniqKey="Derbyshire E" first="Elvira" last="Derbyshire">Elvira Derbyshire</name><affiliation><nlm:aff id="A1">Centre for Infection, Division of Cellular and Molecular Medicine, St. George's, University of London, London SW17 0RE, UK</nlm:aff></affiliation></author><author><name sortKey="Egee, Stephane" sort="Egee, Stephane" uniqKey="Egee S" first="Stéphane" last="Egée">Stéphane Egée</name><affiliation><nlm:aff id="A5">CNRS, UMR 7127, Station Biologique, Place G. Teissier, BP 74, 29682 Roscoff cedex, France</nlm:aff></affiliation></author><author><name sortKey="Ginsburg, Hagai" sort="Ginsburg, Hagai" uniqKey="Ginsburg H" first="Hagai" last="Ginsburg">Hagai Ginsburg</name><affiliation><nlm:aff id="A6">Department of Biological Chemistry, Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel</nlm:aff></affiliation></author><author><name sortKey="Hill, David A" sort="Hill, David A" uniqKey="Hill D" first="David A." last="Hill">David A. Hill</name><affiliation><nlm:aff id="A2">Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA</nlm:aff></affiliation></author><author><name sortKey="Huber, Stephan M" sort="Huber, Stephan M" uniqKey="Huber S" first="Stephan M." last="Huber">Stephan M. Huber</name><affiliation><nlm:aff id="A7">Department of Physiology, University of Tuebingen, Gmelinstrasse 5, D 72076, Tübingen, Germany</nlm:aff></affiliation></author><author><name sortKey="Kirk, Kiaran" sort="Kirk, Kiaran" uniqKey="Kirk K" first="Kiaran" last="Kirk">Kiaran Kirk</name><affiliation><nlm:aff id="A3">School of Biochemistry and Molecular Biology, The Australian National University, Canberra, ACT 0200, Australia</nlm:aff></affiliation></author><author><name sortKey="Lang, Florian" sort="Lang, Florian" uniqKey="Lang F" first="Florian" last="Lang">Florian Lang</name><affiliation><nlm:aff id="A7">Department of Physiology, University of Tuebingen, Gmelinstrasse 5, D 72076, Tübingen, Germany</nlm:aff></affiliation></author><author><name sortKey="Lisk, Godfrey" sort="Lisk, Godfrey" uniqKey="Lisk G" first="Godfrey" last="Lisk">Godfrey Lisk</name><affiliation><nlm:aff id="A2">Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA</nlm:aff></affiliation></author><author><name sortKey="Oteng, Eugene" sort="Oteng, Eugene" uniqKey="Oteng E" first="Eugene" last="Oteng">Eugene Oteng</name><affiliation><nlm:aff id="A2">Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA</nlm:aff></affiliation></author><author><name sortKey="Pillai, Ajay D" sort="Pillai, Ajay D" uniqKey="Pillai A" first="Ajay D." last="Pillai">Ajay D. Pillai</name><affiliation><nlm:aff id="A2">Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA</nlm:aff></affiliation></author><author><name sortKey="Rayavara, Kempaiah" sort="Rayavara, Kempaiah" uniqKey="Rayavara K" first="Kempaiah" last="Rayavara">Kempaiah Rayavara</name><affiliation><nlm:aff id="A2">Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA</nlm:aff></affiliation></author><author><name sortKey="Rouhani, Sherin" sort="Rouhani, Sherin" uniqKey="Rouhani S" first="Sherin" last="Rouhani">Sherin Rouhani</name><affiliation><nlm:aff id="A2">Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA</nlm:aff></affiliation></author><author><name sortKey="Saliba, Kevin J" sort="Saliba, Kevin J" uniqKey="Saliba K" first="Kevin J." last="Saliba">Kevin J. Saliba</name><affiliation><nlm:aff id="A3">School of Biochemistry and Molecular Biology, The Australian National University, Canberra, ACT 0200, Australia</nlm:aff></affiliation><affiliation><nlm:aff id="A8">Medical School, The Australian National University, Canberra, ACT 0200, Australia</nlm:aff></affiliation></author><author><name sortKey="Shen, Crystal" sort="Shen, Crystal" uniqKey="Shen C" first="Crystal" last="Shen">Crystal Shen</name><affiliation><nlm:aff id="A2">Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA</nlm:aff></affiliation></author><author><name sortKey="Solomon, Tsione" sort="Solomon, Tsione" uniqKey="Solomon T" first="Tsione" last="Solomon">Tsione Solomon</name><affiliation><nlm:aff id="A2">Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA</nlm:aff></affiliation></author><author><name sortKey="Thomas, Serge L Y" sort="Thomas, Serge L Y" uniqKey="Thomas S" first="Serge L. Y." last="Thomas">Serge L. Y. Thomas</name><affiliation><nlm:aff id="A5">CNRS, UMR 7127, Station Biologique, Place G. Teissier, BP 74, 29682 Roscoff cedex, France</nlm:aff></affiliation></author><author><name sortKey="Verloo, Patrick" sort="Verloo, Patrick" uniqKey="Verloo P" first="Patrick" last="Verloo">Patrick Verloo</name><affiliation><nlm:aff id="A4">Department of Biochemistry, Erasmus University Medical Center, 3000 DR Rotterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Desai, Sanjay A" sort="Desai, Sanjay A" uniqKey="Desai S" first="Sanjay A." last="Desai">Sanjay A. Desai</name><affiliation><nlm:aff id="A2">Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">17292372</idno><idno type="pmc">2746352</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746352</idno><idno type="RBID">PMC:2746352</idno><idno type="doi">10.1016/j.ijpara.2006.12.013</idno><date when="2007">2007</date><idno type="wicri:Area/Pmc/Corpus">001399</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001399</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Electrophysiological studies of malaria parasite-infected erythrocytes: Current status</title><author><name sortKey="Staines, Henry M" sort="Staines, Henry M" uniqKey="Staines H" first="Henry M." last="Staines">Henry M. Staines</name><affiliation><nlm:aff id="A1">Centre for Infection, Division of Cellular and Molecular Medicine, St. George's, University of London, London SW17 0RE, UK</nlm:aff></affiliation></author><author><name sortKey="Alkhalil, Abdulnaser" sort="Alkhalil, Abdulnaser" uniqKey="Alkhalil A" first="Abdulnaser" last="Alkhalil">Abdulnaser Alkhalil</name><affiliation><nlm:aff id="A2">Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA</nlm:aff></affiliation></author><author><name sortKey="Allen, Richard J" sort="Allen, Richard J" uniqKey="Allen R" first="Richard J." last="Allen">Richard J. Allen</name><affiliation><nlm:aff id="A3">School of Biochemistry and Molecular Biology, The Australian National University, Canberra, ACT 0200, Australia</nlm:aff></affiliation></author><author><name sortKey="De Jonge, Hugo R" sort="De Jonge, Hugo R" uniqKey="De Jonge H" first="Hugo R." last="De Jonge">Hugo R. De Jonge</name><affiliation><nlm:aff id="A4">Department of Biochemistry, Erasmus University Medical Center, 3000 DR Rotterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Derbyshire, Elvira" sort="Derbyshire, Elvira" uniqKey="Derbyshire E" first="Elvira" last="Derbyshire">Elvira Derbyshire</name><affiliation><nlm:aff id="A1">Centre for Infection, Division of Cellular and Molecular Medicine, St. George's, University of London, London SW17 0RE, UK</nlm:aff></affiliation></author><author><name sortKey="Egee, Stephane" sort="Egee, Stephane" uniqKey="Egee S" first="Stéphane" last="Egée">Stéphane Egée</name><affiliation><nlm:aff id="A5">CNRS, UMR 7127, Station Biologique, Place G. Teissier, BP 74, 29682 Roscoff cedex, France</nlm:aff></affiliation></author><author><name sortKey="Ginsburg, Hagai" sort="Ginsburg, Hagai" uniqKey="Ginsburg H" first="Hagai" last="Ginsburg">Hagai Ginsburg</name><affiliation><nlm:aff id="A6">Department of Biological Chemistry, Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel</nlm:aff></affiliation></author><author><name sortKey="Hill, David A" sort="Hill, David A" uniqKey="Hill D" first="David A." last="Hill">David A. Hill</name><affiliation><nlm:aff id="A2">Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA</nlm:aff></affiliation></author><author><name sortKey="Huber, Stephan M" sort="Huber, Stephan M" uniqKey="Huber S" first="Stephan M." last="Huber">Stephan M. Huber</name><affiliation><nlm:aff id="A7">Department of Physiology, University of Tuebingen, Gmelinstrasse 5, D 72076, Tübingen, Germany</nlm:aff></affiliation></author><author><name sortKey="Kirk, Kiaran" sort="Kirk, Kiaran" uniqKey="Kirk K" first="Kiaran" last="Kirk">Kiaran Kirk</name><affiliation><nlm:aff id="A3">School of Biochemistry and Molecular Biology, The Australian National University, Canberra, ACT 0200, Australia</nlm:aff></affiliation></author><author><name sortKey="Lang, Florian" sort="Lang, Florian" uniqKey="Lang F" first="Florian" last="Lang">Florian Lang</name><affiliation><nlm:aff id="A7">Department of Physiology, University of Tuebingen, Gmelinstrasse 5, D 72076, Tübingen, Germany</nlm:aff></affiliation></author><author><name sortKey="Lisk, Godfrey" sort="Lisk, Godfrey" uniqKey="Lisk G" first="Godfrey" last="Lisk">Godfrey Lisk</name><affiliation><nlm:aff id="A2">Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA</nlm:aff></affiliation></author><author><name sortKey="Oteng, Eugene" sort="Oteng, Eugene" uniqKey="Oteng E" first="Eugene" last="Oteng">Eugene Oteng</name><affiliation><nlm:aff id="A2">Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA</nlm:aff></affiliation></author><author><name sortKey="Pillai, Ajay D" sort="Pillai, Ajay D" uniqKey="Pillai A" first="Ajay D." last="Pillai">Ajay D. Pillai</name><affiliation><nlm:aff id="A2">Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA</nlm:aff></affiliation></author><author><name sortKey="Rayavara, Kempaiah" sort="Rayavara, Kempaiah" uniqKey="Rayavara K" first="Kempaiah" last="Rayavara">Kempaiah Rayavara</name><affiliation><nlm:aff id="A2">Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA</nlm:aff></affiliation></author><author><name sortKey="Rouhani, Sherin" sort="Rouhani, Sherin" uniqKey="Rouhani S" first="Sherin" last="Rouhani">Sherin Rouhani</name><affiliation><nlm:aff id="A2">Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA</nlm:aff></affiliation></author><author><name sortKey="Saliba, Kevin J" sort="Saliba, Kevin J" uniqKey="Saliba K" first="Kevin J." last="Saliba">Kevin J. Saliba</name><affiliation><nlm:aff id="A3">School of Biochemistry and Molecular Biology, The Australian National University, Canberra, ACT 0200, Australia</nlm:aff></affiliation><affiliation><nlm:aff id="A8">Medical School, The Australian National University, Canberra, ACT 0200, Australia</nlm:aff></affiliation></author><author><name sortKey="Shen, Crystal" sort="Shen, Crystal" uniqKey="Shen C" first="Crystal" last="Shen">Crystal Shen</name><affiliation><nlm:aff id="A2">Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA</nlm:aff></affiliation></author><author><name sortKey="Solomon, Tsione" sort="Solomon, Tsione" uniqKey="Solomon T" first="Tsione" last="Solomon">Tsione Solomon</name><affiliation><nlm:aff id="A2">Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA</nlm:aff></affiliation></author><author><name sortKey="Thomas, Serge L Y" sort="Thomas, Serge L Y" uniqKey="Thomas S" first="Serge L. Y." last="Thomas">Serge L. Y. Thomas</name><affiliation><nlm:aff id="A5">CNRS, UMR 7127, Station Biologique, Place G. Teissier, BP 74, 29682 Roscoff cedex, France</nlm:aff></affiliation></author><author><name sortKey="Verloo, Patrick" sort="Verloo, Patrick" uniqKey="Verloo P" first="Patrick" last="Verloo">Patrick Verloo</name><affiliation><nlm:aff id="A4">Department of Biochemistry, Erasmus University Medical Center, 3000 DR Rotterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Desai, Sanjay A" sort="Desai, Sanjay A" uniqKey="Desai S" first="Sanjay A." last="Desai">Sanjay A. Desai</name><affiliation><nlm:aff id="A2">Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA</nlm:aff></affiliation></author></analytic><series><title level="j">International journal for parasitology</title><idno type="ISSN">0020-7519</idno><idno type="eISSN">1879-0135</idno><imprint><date when="2007">2007</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">The altered permeability characteristics of erythrocytes infected with malaria parasites have been a source of interest for over 30 years. Recent electrophysiological studies have provided strong evidence that these changes reflect transmembrane transport through ion channels in the host erythrocyte plasma membrane. However, conflicting results and differing interpretations of the data have led to confusion in this field. In an effort to unravel these issues, the groups involved recently came together for a week of discussion and experimentation. In this article, the various models for altered transport are reviewed, together with the areas of consensus in the field and those that require a better understanding.</p></div></front></TEI><pmc article-type="research-article" xml:lang="EN"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">0314024</journal-id><journal-id journal-id-type="pubmed-jr-id">4319</journal-id><journal-id journal-id-type="nlm-ta">Int J Parasitol</journal-id><journal-title>International journal for parasitology</journal-title><issn pub-type="ppub">0020-7519</issn><issn pub-type="epub">1879-0135</issn></journal-meta><article-meta><article-id pub-id-type="pmid">17292372</article-id><article-id pub-id-type="pmc">2746352</article-id><article-id pub-id-type="doi">10.1016/j.ijpara.2006.12.013</article-id><article-id pub-id-type="manuscript">NIHMS125101</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Electrophysiological studies of malaria parasite-infected erythrocytes: Current status</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Staines</surname><given-names>Henry M.</given-names></name><xref ref-type="aff" rid="A1">a</xref><xref ref-type="corresp" rid="CR1">*</xref></contrib><contrib contrib-type="author"><name><surname>Alkhalil</surname><given-names>Abdulnaser</given-names></name><xref ref-type="aff" rid="A2">b</xref></contrib><contrib contrib-type="author"><name><surname>Allen</surname><given-names>Richard J.</given-names></name><xref ref-type="aff" rid="A3">c</xref></contrib><contrib contrib-type="author"><name><surname>De Jonge</surname><given-names>Hugo R.</given-names></name><xref ref-type="aff" rid="A4">d</xref></contrib><contrib contrib-type="author"><name><surname>Derbyshire</surname><given-names>Elvira</given-names></name><xref ref-type="aff" rid="A1">a</xref></contrib><contrib contrib-type="author"><name><surname>Egée</surname><given-names>Stéphane</given-names></name><xref ref-type="aff" rid="A5">e</xref></contrib><contrib contrib-type="author"><name><surname>Ginsburg</surname><given-names>Hagai</given-names></name><xref ref-type="aff" rid="A6">f</xref></contrib><contrib contrib-type="author"><name><surname>Hill</surname><given-names>David A.</given-names></name><xref ref-type="aff" rid="A2">b</xref></contrib><contrib contrib-type="author"><name><surname>Huber</surname><given-names>Stephan M.</given-names></name><xref ref-type="aff" rid="A7">g</xref></contrib><contrib contrib-type="author"><name><surname>Kirk</surname><given-names>Kiaran</given-names></name><xref ref-type="aff" rid="A3">c</xref></contrib><contrib contrib-type="author"><name><surname>Lang</surname><given-names>Florian</given-names></name><xref ref-type="aff" rid="A7">g</xref></contrib><contrib contrib-type="author"><name><surname>Lisk</surname><given-names>Godfrey</given-names></name><xref ref-type="aff" rid="A2">b</xref></contrib><contrib contrib-type="author"><name><surname>Oteng</surname><given-names>Eugene</given-names></name><xref ref-type="aff" rid="A2">b</xref></contrib><contrib contrib-type="author"><name><surname>Pillai</surname><given-names>Ajay D.</given-names></name><xref ref-type="aff" rid="A2">b</xref></contrib><contrib contrib-type="author"><name><surname>Rayavara</surname><given-names>Kempaiah</given-names></name><xref ref-type="aff" rid="A2">b</xref></contrib><contrib contrib-type="author"><name><surname>Rouhani</surname><given-names>Sherin</given-names></name><xref ref-type="aff" rid="A2">b</xref></contrib><contrib contrib-type="author"><name><surname>Saliba</surname><given-names>Kevin J.</given-names></name><xref ref-type="aff" rid="A3">c</xref><xref ref-type="aff" rid="A8">h</xref></contrib><contrib contrib-type="author"><name><surname>Shen</surname><given-names>Crystal</given-names></name><xref ref-type="aff" rid="A2">b</xref></contrib><contrib contrib-type="author"><name><surname>Solomon</surname><given-names>Tsione</given-names></name><xref ref-type="aff" rid="A2">b</xref></contrib><contrib contrib-type="author"><name><surname>Thomas</surname><given-names>Serge L. Y.</given-names></name><xref ref-type="aff" rid="A5">e</xref></contrib><contrib contrib-type="author"><name><surname>Verloo</surname><given-names>Patrick</given-names></name><xref ref-type="aff" rid="A4">d</xref></contrib><contrib contrib-type="author"><name><surname>Desai</surname><given-names>Sanjay A.</given-names></name><xref ref-type="aff" rid="A2">b</xref></contrib></contrib-group><aff id="A1"><label>a</label>Centre for Infection, Division of Cellular and Molecular Medicine, St. George's, University of London, London SW17 0RE, UK</aff><aff id="A2"><label>b</label>Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA</aff><aff id="A3"><label>c</label>School of Biochemistry and Molecular Biology, The Australian National University, Canberra, ACT 0200, Australia</aff><aff id="A4"><label>d</label>Department of Biochemistry, Erasmus University Medical Center, 3000 DR Rotterdam, The Netherlands</aff><aff id="A5"><label>e</label>CNRS, UMR 7127, Station Biologique, Place G. Teissier, BP 74, 29682 Roscoff cedex, France</aff><aff id="A6"><label>f</label>Department of Biological Chemistry, Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel</aff><aff id="A7"><label>g</label>Department of Physiology, University of Tuebingen, Gmelinstrasse 5, D 72076, Tübingen, Germany</aff><aff id="A8"><label>h</label>Medical School, The Australian National University, Canberra, ACT 0200, Australia</aff><author-notes><corresp id="CR1"><label>*</label>Corresponding author Dr Henry Staines, Centre for Infection, Division of Cellular and Molecular Medicine, St. George's, University of London, London SW17 0RE United Kingdom Tel.: +44 208 7255722; fax: +44 208 7253487. <italic>E-mail address:</italic> <email>hstaines@sgul.ac.uk</email></corresp></author-notes><pub-date pub-type="nihms-submitted"><day>23</day><month>6</month><year>2009</year></pub-date><pub-date pub-type="epub"><day>9</day><month>1</month><year>2007</year></pub-date><pub-date pub-type="ppub"><month>4</month><year>2007</year></pub-date><pub-date pub-type="pmc-release"><day>18</day><month>9</month><year>2009</year></pub-date><volume>37</volume><issue>5</issue><fpage>475</fpage><lpage>482</lpage><permissions><copyright-statement>© 2009 Australian Society for Parasitology. Published by Elsevier Ltd. All rights reserved</copyright-statement><copyright-year>2009</copyright-year></permissions><abstract><p id="P1">The altered permeability characteristics of erythrocytes infected with malaria parasites have been a source of interest for over 30 years. Recent electrophysiological studies have provided strong evidence that these changes reflect transmembrane transport through ion channels in the host erythrocyte plasma membrane. However, conflicting results and differing interpretations of the data have led to confusion in this field. In an effort to unravel these issues, the groups involved recently came together for a week of discussion and experimentation. In this article, the various models for altered transport are reviewed, together with the areas of consensus in the field and those that require a better understanding.</p></abstract><kwd-group><kwd>Patch-clamp</kwd><kwd>Ion channels</kwd><kwd>New permeability pathways</kwd><kwd>PSAC</kwd><kwd><italic>Plasmodium</italic></kwd><kwd>Oxidation</kwd></kwd-group><contract-num rid="AI1">Z01 AI000882-07</contract-num><contract-sponsor id="AI1">National Institute of Allergy and Infectious Diseases Extramural Activities : NIAID</contract-sponsor></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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