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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">RNAcentral: A vision for an international database of RNA sequences</title><author><name sortKey="Bateman, Alex" sort="Bateman, Alex" uniqKey="Bateman A" first="Alex" last="Bateman">Alex Bateman</name><affiliation><nlm:aff id="aff1">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Agrawal, Shipra" sort="Agrawal, Shipra" uniqKey="Agrawal S" first="Shipra" last="Agrawal">Shipra Agrawal</name><affiliation><nlm:aff id="aff2">Institute of Bioinformatics and Applied Biotechnology (IBAB), Bangalore 560 100, India</nlm:aff></affiliation><affiliation><nlm:aff id="aff3">BioCOS Life Sciences Private Limited, Bangalore 560 100, India</nlm:aff></affiliation></author><author><name sortKey="Birney, Ewan" sort="Birney, Ewan" uniqKey="Birney E" first="Ewan" last="Birney">Ewan Birney</name><affiliation><nlm:aff id="aff4">European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SD, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Bruford, Elspeth A" sort="Bruford, Elspeth A" uniqKey="Bruford E" first="Elspeth A." last="Bruford">Elspeth A. Bruford</name><affiliation><nlm:aff id="aff4">European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SD, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Bujnicki, Janusz M" sort="Bujnicki, Janusz M" uniqKey="Bujnicki J" first="Janusz M." last="Bujnicki">Janusz M. Bujnicki</name><affiliation><nlm:aff id="aff5">Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw, Trojdena 4, 02-109 Warsaw, Poland</nlm:aff></affiliation><affiliation><nlm:aff id="aff6">Laboratory of Bioinformatics, Institute of Molecular Biology and Biotechnology, Faculty of Biology, Umultowska 89, 61-614 Poznan, Poland</nlm:aff></affiliation></author><author><name sortKey="Cochrane, Guy" sort="Cochrane, Guy" uniqKey="Cochrane G" first="Guy" last="Cochrane">Guy Cochrane</name><affiliation><nlm:aff id="aff4">European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SD, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Cole, James R" sort="Cole, James R" uniqKey="Cole J" first="James R." last="Cole">James R. Cole</name><affiliation><nlm:aff id="aff7">Microbial Ecology Center, Michigan State University, East Lansing, Michigan 48824-1319, USA</nlm:aff></affiliation></author><author><name sortKey="Dinger, Marcel E" sort="Dinger, Marcel E" uniqKey="Dinger M" first="Marcel E." last="Dinger">Marcel E. Dinger</name><affiliation><nlm:aff id="aff8">Institute for Molecular Bioscience, The University of Queensland, St Lucia QLD 4072, Australia</nlm:aff></affiliation></author><author><name sortKey="Enright, Anton J" sort="Enright, Anton J" uniqKey="Enright A" first="Anton J." last="Enright">Anton J. Enright</name><affiliation><nlm:aff id="aff4">European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SD, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Gardner, Paul P" sort="Gardner, Paul P" uniqKey="Gardner P" first="Paul P." last="Gardner">Paul P. Gardner</name><affiliation><nlm:aff id="aff1">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Gautheret, Daniel" sort="Gautheret, Daniel" uniqKey="Gautheret D" first="Daniel" last="Gautheret">Daniel Gautheret</name><affiliation><nlm:aff id="aff9">Institut de Génétique et Microbiologie–UMR CNRS 8621, Université Paris-Sud–Bâtiment 400, 91405 Orsay Cedex, France</nlm:aff></affiliation></author><author><name sortKey="Griffiths Jones, Sam" sort="Griffiths Jones, Sam" uniqKey="Griffiths Jones S" first="Sam" last="Griffiths-Jones">Sam Griffiths-Jones</name><affiliation><nlm:aff id="aff10">Faculty of Life Sciences, University of Manchester, Michael Smith Building, Manchester, M13 9PT, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Harrow, Jen" sort="Harrow, Jen" uniqKey="Harrow J" first="Jen" last="Harrow">Jen Harrow</name><affiliation><nlm:aff id="aff1">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Herrero, Javier" sort="Herrero, Javier" uniqKey="Herrero J" first="Javier" last="Herrero">Javier Herrero</name><affiliation><nlm:aff id="aff4">European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SD, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Holmes, Ian H" sort="Holmes, Ian H" uniqKey="Holmes I" first="Ian H." last="Holmes">Ian H. Holmes</name><affiliation><nlm:aff id="aff11">Department of Bioengineering, University of California, Berkeley, California 94720-1762, USA</nlm:aff></affiliation></author><author><name sortKey="Huang, Hsien Da" sort="Huang, Hsien Da" uniqKey="Huang H" first="Hsien-Da" last="Huang">Hsien-Da Huang</name><affiliation><nlm:aff id="aff12">Institute of Bioinformatics and Systems Biology, National Chiao Tung University, HsinChu, 30050, Taiwan</nlm:aff></affiliation></author><author><name sortKey="Kelly, Krystyna A" sort="Kelly, Krystyna A" uniqKey="Kelly K" first="Krystyna A." last="Kelly">Krystyna A. Kelly</name><affiliation><nlm:aff id="aff13">Department of Plant Sciences, University of Cambridge, Cambridge CB2 3EA, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Kersey, Paul" sort="Kersey, Paul" uniqKey="Kersey P" first="Paul" last="Kersey">Paul Kersey</name><affiliation><nlm:aff id="aff4">European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SD, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Kozomara, Ana" sort="Kozomara, Ana" uniqKey="Kozomara A" first="Ana" last="Kozomara">Ana Kozomara</name><affiliation><nlm:aff id="aff10">Faculty of Life Sciences, University of Manchester, Michael Smith Building, Manchester, M13 9PT, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Lowe, Todd M" sort="Lowe, Todd M" uniqKey="Lowe T" first="Todd M." last="Lowe">Todd M. Lowe</name><affiliation><nlm:aff id="aff14">Department of Biomolecular Engineering, University of California, Santa Cruz, California 95064, USA</nlm:aff></affiliation></author><author><name sortKey="Marz, Manja" sort="Marz, Manja" uniqKey="Marz M" first="Manja" last="Marz">Manja Marz</name><affiliation><nlm:aff id="aff15">RNA Bioinformatics Group, Institute of Pharmaceutical Chemistry, Marbacher Weg 6, 35037 Marburg, Germany</nlm:aff></affiliation></author><author><name sortKey="Moxon, Simon" sort="Moxon, Simon" uniqKey="Moxon S" first="Simon" last="Moxon">Simon Moxon</name><affiliation><nlm:aff id="aff16">University of East Anglia, Norwich, NR4 7TJ, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Pruitt, Kim D" sort="Pruitt, Kim D" uniqKey="Pruitt K" first="Kim D." last="Pruitt">Kim D. Pruitt</name><affiliation><nlm:aff id="aff17">National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland 20894, USA</nlm:aff></affiliation></author><author><name sortKey="Samuelsson, Tore" sort="Samuelsson, Tore" uniqKey="Samuelsson T" first="Tore" last="Samuelsson">Tore Samuelsson</name><affiliation><nlm:aff id="aff18">Department of Medical Biochemistry, University of Goteborg, Medicinareg. 9A, S-405 30 Goteborg, Sweden</nlm:aff></affiliation></author><author><name sortKey="Stadler, Peter F" sort="Stadler, Peter F" uniqKey="Stadler P" first="Peter F." last="Stadler">Peter F. Stadler</name><affiliation><nlm:aff id="aff19">Bioinformatics Group, Department of Computer Science, and Interdisciplinary Center for Bioinformatics, University of Leipzig, 04009 Leipzig, Germany</nlm:aff></affiliation></author><author><name sortKey="Vilella, Albert J" sort="Vilella, Albert J" uniqKey="Vilella A" first="Albert J." last="Vilella">Albert J. Vilella</name><affiliation><nlm:aff id="aff4">European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SD, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Vogel, Jan Hinnerk" sort="Vogel, Jan Hinnerk" uniqKey="Vogel J" first="Jan-Hinnerk" last="Vogel">Jan-Hinnerk Vogel</name><affiliation><nlm:aff id="aff1">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Williams, Kelly P" sort="Williams, Kelly P" uniqKey="Williams K" first="Kelly P." last="Williams">Kelly P. Williams</name><affiliation><nlm:aff id="aff20">Sandia National Laboratories, MS 9291, Livermore, California 94551-0969, USA</nlm:aff></affiliation></author><author><name sortKey="Wright, Mathew W" sort="Wright, Mathew W" uniqKey="Wright M" first="Mathew W." last="Wright">Mathew W. Wright</name><affiliation><nlm:aff id="aff4">European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SD, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Zwieb, Christian" sort="Zwieb, Christian" uniqKey="Zwieb C" first="Christian" last="Zwieb">Christian Zwieb</name><affiliation><nlm:aff id="aff21">Department of Biochemistry, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229-3901, USA</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">21940779</idno><idno type="pmc">3198587</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198587</idno><idno type="RBID">PMC:3198587</idno><idno type="doi">10.1261/rna.2750811</idno><date when="2011">2011</date><idno type="wicri:Area/Pmc/Corpus">001311</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001311</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">RNAcentral: A vision for an international database of RNA sequences</title><author><name sortKey="Bateman, Alex" sort="Bateman, Alex" uniqKey="Bateman A" first="Alex" last="Bateman">Alex Bateman</name><affiliation><nlm:aff id="aff1">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Agrawal, Shipra" sort="Agrawal, Shipra" uniqKey="Agrawal S" first="Shipra" last="Agrawal">Shipra Agrawal</name><affiliation><nlm:aff id="aff2">Institute of Bioinformatics and Applied Biotechnology (IBAB), Bangalore 560 100, India</nlm:aff></affiliation><affiliation><nlm:aff id="aff3">BioCOS Life Sciences Private Limited, Bangalore 560 100, India</nlm:aff></affiliation></author><author><name sortKey="Birney, Ewan" sort="Birney, Ewan" uniqKey="Birney E" first="Ewan" last="Birney">Ewan Birney</name><affiliation><nlm:aff id="aff4">European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SD, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Bruford, Elspeth A" sort="Bruford, Elspeth A" uniqKey="Bruford E" first="Elspeth A." last="Bruford">Elspeth A. Bruford</name><affiliation><nlm:aff id="aff4">European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SD, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Bujnicki, Janusz M" sort="Bujnicki, Janusz M" uniqKey="Bujnicki J" first="Janusz M." last="Bujnicki">Janusz M. Bujnicki</name><affiliation><nlm:aff id="aff5">Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw, Trojdena 4, 02-109 Warsaw, Poland</nlm:aff></affiliation><affiliation><nlm:aff id="aff6">Laboratory of Bioinformatics, Institute of Molecular Biology and Biotechnology, Faculty of Biology, Umultowska 89, 61-614 Poznan, Poland</nlm:aff></affiliation></author><author><name sortKey="Cochrane, Guy" sort="Cochrane, Guy" uniqKey="Cochrane G" first="Guy" last="Cochrane">Guy Cochrane</name><affiliation><nlm:aff id="aff4">European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SD, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Cole, James R" sort="Cole, James R" uniqKey="Cole J" first="James R." last="Cole">James R. Cole</name><affiliation><nlm:aff id="aff7">Microbial Ecology Center, Michigan State University, East Lansing, Michigan 48824-1319, USA</nlm:aff></affiliation></author><author><name sortKey="Dinger, Marcel E" sort="Dinger, Marcel E" uniqKey="Dinger M" first="Marcel E." last="Dinger">Marcel E. Dinger</name><affiliation><nlm:aff id="aff8">Institute for Molecular Bioscience, The University of Queensland, St Lucia QLD 4072, Australia</nlm:aff></affiliation></author><author><name sortKey="Enright, Anton J" sort="Enright, Anton J" uniqKey="Enright A" first="Anton J." last="Enright">Anton J. Enright</name><affiliation><nlm:aff id="aff4">European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SD, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Gardner, Paul P" sort="Gardner, Paul P" uniqKey="Gardner P" first="Paul P." last="Gardner">Paul P. Gardner</name><affiliation><nlm:aff id="aff1">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Gautheret, Daniel" sort="Gautheret, Daniel" uniqKey="Gautheret D" first="Daniel" last="Gautheret">Daniel Gautheret</name><affiliation><nlm:aff id="aff9">Institut de Génétique et Microbiologie–UMR CNRS 8621, Université Paris-Sud–Bâtiment 400, 91405 Orsay Cedex, France</nlm:aff></affiliation></author><author><name sortKey="Griffiths Jones, Sam" sort="Griffiths Jones, Sam" uniqKey="Griffiths Jones S" first="Sam" last="Griffiths-Jones">Sam Griffiths-Jones</name><affiliation><nlm:aff id="aff10">Faculty of Life Sciences, University of Manchester, Michael Smith Building, Manchester, M13 9PT, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Harrow, Jen" sort="Harrow, Jen" uniqKey="Harrow J" first="Jen" last="Harrow">Jen Harrow</name><affiliation><nlm:aff id="aff1">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Herrero, Javier" sort="Herrero, Javier" uniqKey="Herrero J" first="Javier" last="Herrero">Javier Herrero</name><affiliation><nlm:aff id="aff4">European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SD, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Holmes, Ian H" sort="Holmes, Ian H" uniqKey="Holmes I" first="Ian H." last="Holmes">Ian H. Holmes</name><affiliation><nlm:aff id="aff11">Department of Bioengineering, University of California, Berkeley, California 94720-1762, USA</nlm:aff></affiliation></author><author><name sortKey="Huang, Hsien Da" sort="Huang, Hsien Da" uniqKey="Huang H" first="Hsien-Da" last="Huang">Hsien-Da Huang</name><affiliation><nlm:aff id="aff12">Institute of Bioinformatics and Systems Biology, National Chiao Tung University, HsinChu, 30050, Taiwan</nlm:aff></affiliation></author><author><name sortKey="Kelly, Krystyna A" sort="Kelly, Krystyna A" uniqKey="Kelly K" first="Krystyna A." last="Kelly">Krystyna A. Kelly</name><affiliation><nlm:aff id="aff13">Department of Plant Sciences, University of Cambridge, Cambridge CB2 3EA, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Kersey, Paul" sort="Kersey, Paul" uniqKey="Kersey P" first="Paul" last="Kersey">Paul Kersey</name><affiliation><nlm:aff id="aff4">European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SD, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Kozomara, Ana" sort="Kozomara, Ana" uniqKey="Kozomara A" first="Ana" last="Kozomara">Ana Kozomara</name><affiliation><nlm:aff id="aff10">Faculty of Life Sciences, University of Manchester, Michael Smith Building, Manchester, M13 9PT, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Lowe, Todd M" sort="Lowe, Todd M" uniqKey="Lowe T" first="Todd M." last="Lowe">Todd M. Lowe</name><affiliation><nlm:aff id="aff14">Department of Biomolecular Engineering, University of California, Santa Cruz, California 95064, USA</nlm:aff></affiliation></author><author><name sortKey="Marz, Manja" sort="Marz, Manja" uniqKey="Marz M" first="Manja" last="Marz">Manja Marz</name><affiliation><nlm:aff id="aff15">RNA Bioinformatics Group, Institute of Pharmaceutical Chemistry, Marbacher Weg 6, 35037 Marburg, Germany</nlm:aff></affiliation></author><author><name sortKey="Moxon, Simon" sort="Moxon, Simon" uniqKey="Moxon S" first="Simon" last="Moxon">Simon Moxon</name><affiliation><nlm:aff id="aff16">University of East Anglia, Norwich, NR4 7TJ, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Pruitt, Kim D" sort="Pruitt, Kim D" uniqKey="Pruitt K" first="Kim D." last="Pruitt">Kim D. Pruitt</name><affiliation><nlm:aff id="aff17">National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland 20894, USA</nlm:aff></affiliation></author><author><name sortKey="Samuelsson, Tore" sort="Samuelsson, Tore" uniqKey="Samuelsson T" first="Tore" last="Samuelsson">Tore Samuelsson</name><affiliation><nlm:aff id="aff18">Department of Medical Biochemistry, University of Goteborg, Medicinareg. 9A, S-405 30 Goteborg, Sweden</nlm:aff></affiliation></author><author><name sortKey="Stadler, Peter F" sort="Stadler, Peter F" uniqKey="Stadler P" first="Peter F." last="Stadler">Peter F. Stadler</name><affiliation><nlm:aff id="aff19">Bioinformatics Group, Department of Computer Science, and Interdisciplinary Center for Bioinformatics, University of Leipzig, 04009 Leipzig, Germany</nlm:aff></affiliation></author><author><name sortKey="Vilella, Albert J" sort="Vilella, Albert J" uniqKey="Vilella A" first="Albert J." last="Vilella">Albert J. Vilella</name><affiliation><nlm:aff id="aff4">European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SD, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Vogel, Jan Hinnerk" sort="Vogel, Jan Hinnerk" uniqKey="Vogel J" first="Jan-Hinnerk" last="Vogel">Jan-Hinnerk Vogel</name><affiliation><nlm:aff id="aff1">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Williams, Kelly P" sort="Williams, Kelly P" uniqKey="Williams K" first="Kelly P." last="Williams">Kelly P. Williams</name><affiliation><nlm:aff id="aff20">Sandia National Laboratories, MS 9291, Livermore, California 94551-0969, USA</nlm:aff></affiliation></author><author><name sortKey="Wright, Mathew W" sort="Wright, Mathew W" uniqKey="Wright M" first="Mathew W." last="Wright">Mathew W. Wright</name><affiliation><nlm:aff id="aff4">European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SD, United Kingdom</nlm:aff></affiliation></author><author><name sortKey="Zwieb, Christian" sort="Zwieb, Christian" uniqKey="Zwieb C" first="Christian" last="Zwieb">Christian Zwieb</name><affiliation><nlm:aff id="aff21">Department of Biochemistry, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229-3901, USA</nlm:aff></affiliation></author></analytic><series><title level="j">RNA</title><idno type="ISSN">1355-8382</idno><idno type="eISSN">1469-9001</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>During the last decade there has been a great increase in the number of noncoding RNA genes identified, including new classes such as microRNAs and piRNAs. There is also a large growth in the amount of experimental characterization of these RNA components. Despite this growth in information, it is still difficult for researchers to access RNA data, because key data resources for noncoding RNAs have not yet been created. The most pressing omission is the lack of a comprehensive RNA sequence database, much like UniProt, which provides a comprehensive set of protein knowledge. In this article we propose the creation of a new open public resource that we term RNAcentral, which will contain a comprehensive collection of RNA sequences and fill an important gap in the provision of biomedical databases. We envision RNA researchers from all over the world joining a federated RNAcentral network, contributing specialized knowledge and databases. RNAcentral would centralize key data that are currently held across a variety of databases, allowing researchers instant access to a single, unified resource. This resource would facilitate the next generation of RNA research and help drive further discoveries, including those that improve food production and human and animal health. We encourage additional RNA database resources and research groups to join this effort. We aim to obtain international network funding to further this endeavor.</p></div></front></TEI><pmc article-type="letter"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">RNA</journal-id><journal-id journal-id-type="publisher-id">RNA</journal-id><journal-title-group><journal-title>RNA</journal-title></journal-title-group><issn pub-type="ppub">1355-8382</issn><issn pub-type="epub">1469-9001</issn><publisher><publisher-name>Cold Spring Harbor Laboratory Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">21940779</article-id><article-id pub-id-type="pmc">3198587</article-id><article-id pub-id-type="medline">9509184</article-id><article-id pub-id-type="publisher-id">RA</article-id><article-id pub-id-type="doi">10.1261/rna.2750811</article-id><article-categories><subj-group subj-group-type="heading"><subject>Letter to the Editor</subject></subj-group></article-categories><title-group><article-title>RNAcentral: A vision for an international database of RNA sequences</article-title><alt-title alt-title-type="left-running">Bateman et al.</alt-title><alt-title alt-title-type="right-running">RNAcentral international database of RNA sequences</alt-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Bateman</surname><given-names>Alex</given-names></name><xref ref-type="aff" rid="aff1">1</xref><xref ref-type="corresp" rid="cor1">22</xref></contrib><contrib contrib-type="author"><name><surname>Agrawal</surname><given-names>Shipra</given-names></name><xref ref-type="aff" rid="aff2">2</xref><xref ref-type="aff" rid="aff3">3</xref></contrib><contrib contrib-type="author"><name><surname>Birney</surname><given-names>Ewan</given-names></name><xref ref-type="aff" rid="aff4">4</xref></contrib><contrib contrib-type="author"><name><surname>Bruford</surname><given-names>Elspeth A.</given-names></name><xref ref-type="aff" rid="aff4">4</xref></contrib><contrib contrib-type="author"><name><surname>Bujnicki</surname><given-names>Janusz M.</given-names></name><xref ref-type="aff" rid="aff5">5</xref><xref ref-type="aff" rid="aff6">6</xref></contrib><contrib contrib-type="author"><name><surname>Cochrane</surname><given-names>Guy</given-names></name><xref ref-type="aff" rid="aff4">4</xref></contrib><contrib contrib-type="author"><name><surname>Cole</surname><given-names>James R.</given-names></name><xref ref-type="aff" rid="aff7">7</xref></contrib><contrib contrib-type="author"><name><surname>Dinger</surname><given-names>Marcel E.</given-names></name><xref ref-type="aff" rid="aff8">8</xref></contrib><contrib contrib-type="author"><name><surname>Enright</surname><given-names>Anton J.</given-names></name><xref ref-type="aff" rid="aff4">4</xref></contrib><contrib contrib-type="author"><name><surname>Gardner</surname><given-names>Paul P.</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Gautheret</surname><given-names>Daniel</given-names></name><xref ref-type="aff" rid="aff9">9</xref></contrib><contrib contrib-type="author"><name><surname>Griffiths-Jones</surname><given-names>Sam</given-names></name><xref ref-type="aff" rid="aff10">10</xref></contrib><contrib contrib-type="author"><name><surname>Harrow</surname><given-names>Jen</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Herrero</surname><given-names>Javier</given-names></name><xref ref-type="aff" rid="aff4">4</xref></contrib><contrib contrib-type="author"><name><surname>Holmes</surname><given-names>Ian H.</given-names></name><xref ref-type="aff" rid="aff11">11</xref></contrib><contrib contrib-type="author"><name><surname>Huang</surname><given-names>Hsien-Da</given-names></name><xref ref-type="aff" rid="aff12">12</xref></contrib><contrib contrib-type="author"><name><surname>Kelly</surname><given-names>Krystyna A.</given-names></name><xref ref-type="aff" rid="aff13">13</xref></contrib><contrib contrib-type="author"><name><surname>Kersey</surname><given-names>Paul</given-names></name><xref ref-type="aff" rid="aff4">4</xref></contrib><contrib contrib-type="author"><name><surname>Kozomara</surname><given-names>Ana</given-names></name><xref ref-type="aff" rid="aff10">10</xref></contrib><contrib contrib-type="author"><name><surname>Lowe</surname><given-names>Todd M.</given-names></name><xref ref-type="aff" rid="aff14">14</xref></contrib><contrib contrib-type="author"><name><surname>Marz</surname><given-names>Manja</given-names></name><xref ref-type="aff" rid="aff15">15</xref></contrib><contrib contrib-type="author"><name><surname>Moxon</surname><given-names>Simon</given-names></name><xref ref-type="aff" rid="aff16">16</xref></contrib><contrib contrib-type="author"><name><surname>Pruitt</surname><given-names>Kim D.</given-names></name><xref ref-type="aff" rid="aff17">17</xref></contrib><contrib contrib-type="author"><name><surname>Samuelsson</surname><given-names>Tore</given-names></name><xref ref-type="aff" rid="aff18">18</xref></contrib><contrib contrib-type="author"><name><surname>Stadler</surname><given-names>Peter F.</given-names></name><xref ref-type="aff" rid="aff19">19</xref></contrib><contrib contrib-type="author"><name><surname>Vilella</surname><given-names>Albert J.</given-names></name><xref ref-type="aff" rid="aff4">4</xref></contrib><contrib contrib-type="author"><name><surname>Vogel</surname><given-names>Jan-Hinnerk</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Williams</surname><given-names>Kelly P.</given-names></name><xref ref-type="aff" rid="aff20">20</xref></contrib><contrib contrib-type="author"><name><surname>Wright</surname><given-names>Mathew W.</given-names></name><xref ref-type="aff" rid="aff4">4</xref></contrib><contrib contrib-type="author"><name><surname>Zwieb</surname><given-names>Christian</given-names></name><xref ref-type="aff" rid="aff21">21</xref></contrib></contrib-group><aff id="aff1"><label>1</label>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA, United Kingdom</aff><aff id="aff2"><label>2</label>Institute of Bioinformatics and Applied Biotechnology (IBAB), Bangalore 560 100, India</aff><aff id="aff3"><label>3</label>BioCOS Life Sciences Private Limited, Bangalore 560 100, India</aff><aff id="aff4"><label>4</label>European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SD, United Kingdom</aff><aff id="aff5"><label>5</label>Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw, Trojdena 4, 02-109 Warsaw, Poland</aff><aff id="aff6"><label>6</label>Laboratory of Bioinformatics, Institute of Molecular Biology and Biotechnology, Faculty of Biology, Umultowska 89, 61-614 Poznan, Poland</aff><aff id="aff7"><label>7</label>Microbial Ecology Center, Michigan State University, East Lansing, Michigan 48824-1319, USA</aff><aff id="aff8"><label>8</label>Institute for Molecular Bioscience, The University of Queensland, St Lucia QLD 4072, Australia</aff><aff id="aff9"><label>9</label>Institut de Génétique et Microbiologie–UMR CNRS 8621, Université Paris-Sud–Bâtiment 400, 91405 Orsay Cedex, France</aff><aff id="aff10"><label>10</label>Faculty of Life Sciences, University of Manchester, Michael Smith Building, Manchester, M13 9PT, United Kingdom</aff><aff id="aff11"><label>11</label>Department of Bioengineering, University of California, Berkeley, California 94720-1762, USA</aff><aff id="aff12"><label>12</label>Institute of Bioinformatics and Systems Biology, National Chiao Tung University, HsinChu, 30050, Taiwan</aff><aff id="aff13"><label>13</label>Department of Plant Sciences, University of Cambridge, Cambridge CB2 3EA, United Kingdom</aff><aff id="aff14"><label>14</label>Department of Biomolecular Engineering, University of California, Santa Cruz, California 95064, USA</aff><aff id="aff15"><label>15</label>RNA Bioinformatics Group, Institute of Pharmaceutical Chemistry, Marbacher Weg 6, 35037 Marburg, Germany</aff><aff id="aff16"><label>16</label>University of East Anglia, Norwich, NR4 7TJ, United Kingdom</aff><aff id="aff17"><label>17</label>National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland 20894, USA</aff><aff id="aff18"><label>18</label>Department of Medical Biochemistry, University of Goteborg, Medicinareg. 9A, S-405 30 Goteborg, Sweden</aff><aff id="aff19"><label>19</label>Bioinformatics Group, Department of Computer Science, and Interdisciplinary Center for Bioinformatics, University of Leipzig, 04009 Leipzig, Germany</aff><aff id="aff20"><label>20</label>Sandia National Laboratories, MS 9291, Livermore, California 94551-0969, USA</aff><aff id="aff21"><label>21</label>Department of Biochemistry, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229-3901, USA</aff><author-notes><corresp id="cor1"><label>22</label><bold>Corresponding author.</bold><bold>E-mail <email>agb@sanger.ac.uk</email>.</bold></corresp></author-notes><pub-date pub-type="ppub"><month>11</month><year>2011</year></pub-date><pub-date pub-type="pmc-release"><month>11</month><year>2011</year></pub-date><pmc-comment> PMC Release delay is 0 months and 0 days and was based on the
<volume>17</volume><issue>11</issue><fpage>1941</fpage><lpage>1946</lpage><history><date date-type="received"><day>31</day><month>3</month><year>2011</year></date><date date-type="accepted"><day>27</day><month>7</month><year>2011</year></date></history><permissions><license license-type="open-access"><license-p>Freely available online through the <italic>RNA</italic> Open Access option.</license-p></license></permissions><self-uri xlink:title="pdf" xlink:type="simple" xlink:href="1941.pdf"></self-uri><abstract><p>During the last decade there has been a great increase in the number of noncoding RNA genes identified, including new classes such as microRNAs and piRNAs. There is also a large growth in the amount of experimental characterization of these RNA components. Despite this growth in information, it is still difficult for researchers to access RNA data, because key data resources for noncoding RNAs have not yet been created. The most pressing omission is the lack of a comprehensive RNA sequence database, much like UniProt, which provides a comprehensive set of protein knowledge. In this article we propose the creation of a new open public resource that we term RNAcentral, which will contain a comprehensive collection of RNA sequences and fill an important gap in the provision of biomedical databases. We envision RNA researchers from all over the world joining a federated RNAcentral network, contributing specialized knowledge and databases. RNAcentral would centralize key data that are currently held across a variety of databases, allowing researchers instant access to a single, unified resource. This resource would facilitate the next generation of RNA research and help drive further discoveries, including those that improve food production and human and animal health. We encourage additional RNA database resources and research groups to join this effort. We aim to obtain international network funding to further this endeavor.</p></abstract><kwd-group><kwd>sequence database</kwd><kwd>federation</kwd><kwd>noncoding RNA</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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