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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5)</title><author><name sortKey="Bousquet, J" sort="Bousquet, J" uniqKey="Bousquet J" first="J." last="Bousquet">J. Bousquet</name><affiliation><nlm:aff id="Aff1">CHRU, University Hospital, 371 Avenue du Doyen Gaston Giraud, 34295 Montpellier Cedex 5, France</nlm:aff></affiliation><affiliation><nlm:aff id="Aff2">MACVIA-LR, Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc Roussilon, European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier, France</nlm:aff></affiliation><affiliation><nlm:aff id="Aff3">INSERM, VIMA: Ageing and Chronic Diseases, Epidemiological and Public Health Approaches, U1168, Paris, France</nlm:aff></affiliation><affiliation><nlm:aff id="Aff4">UVSQ, UMR-S 1168, Université Versailles St-Quentin-en-Yvelines, Paris, France</nlm:aff></affiliation></author><author><name sortKey="Farrell, J" sort="Farrell, J" uniqKey="Farrell J" first="J." last="Farrell">J. Farrell</name><affiliation><nlm:aff id="Aff5">Department of Health, Social Services and Public Safety, Belfast, Northern Ireland, UK</nlm:aff></affiliation></author><author><name sortKey="Crooks, G" sort="Crooks, G" uniqKey="Crooks G" first="G." last="Crooks">G. Crooks</name><affiliation><nlm:aff id="Aff6">EIP on AHA, European Innovation Partnership on Active and Healthy Ageing, Reference Site, Scottish Centre for Telehealth and Telecare, NHS 24, Glasgow, UK</nlm:aff></affiliation></author><author><name sortKey="Hellings, P" sort="Hellings, P" uniqKey="Hellings P" first="P." last="Hellings">P. Hellings</name><affiliation><nlm:aff id="Aff7">Laboratory of Clinical Immunology, Department of Microbiology and Immunology, KU Leuven, Louvain, Belgium</nlm:aff></affiliation><affiliation><nlm:aff id="Aff8">European Academy of Allergy and Clinical Immunology, Zurich, Switzerland</nlm:aff></affiliation></author><author><name sortKey="Bel, E H" sort="Bel, E H" uniqKey="Bel E" first="E. H." last="Bel">E. H. Bel</name><affiliation><nlm:aff id="Aff9">Department of Respiratory Medicine, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, The Netherlands</nlm:aff></affiliation><affiliation><nlm:aff id="Aff10">European Respiratory Society, Lausanne, Switzerland</nlm:aff></affiliation></author><author><name sortKey="Bewick, M" sort="Bewick, M" uniqKey="Bewick M" first="M." last="Bewick">M. Bewick</name><affiliation><nlm:aff id="Aff11">iQ4U Consultants Ltd, London, UK</nlm:aff></affiliation></author><author><name sortKey="Chavannes, N H" sort="Chavannes, N H" uniqKey="Chavannes N" first="N. H." last="Chavannes">N. H. Chavannes</name><affiliation><nlm:aff id="Aff12">Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands</nlm:aff></affiliation><affiliation><nlm:aff id="Aff13">Global Alliance Against Chronic Respiratory Diseases (GARD), Cape Town, South Africa</nlm:aff></affiliation><affiliation><nlm:aff id="Aff14">International Primary Care Respiratory Group, Westhill, UK</nlm:aff></affiliation></author><author><name sortKey="De Sousa, J Correia" sort="De Sousa, J Correia" uniqKey="De Sousa J" first="J. Correia" last="De Sousa">J. Correia De Sousa</name><affiliation><nlm:aff id="Aff15">Life and Health Sciences Research Institute, ICVS, School of Health Sciences, University of Minho, Braga, Portugal</nlm:aff></affiliation></author><author><name sortKey="Cruz, A A" sort="Cruz, A A" uniqKey="Cruz A" first="A. A." last="Cruz">A. A. Cruz</name><affiliation><nlm:aff id="Aff13">Global Alliance Against Chronic Respiratory Diseases (GARD), Cape Town, South Africa</nlm:aff></affiliation><affiliation><nlm:aff id="Aff16">ProAR – Nucleo de Excelencia em Asma, Federal University of Bahia, Bahia, Brazil</nlm:aff></affiliation><affiliation><nlm:aff id="Aff17">GARD Executive Committee, Bahia, Brazil</nlm:aff></affiliation></author><author><name sortKey="Haahtela, T" sort="Haahtela, T" uniqKey="Haahtela T" first="T." last="Haahtela">T. Haahtela</name><affiliation><nlm:aff id="Aff18">EIP on AHA Commitment for Action, Lisbon, Portugal</nlm:aff></affiliation><affiliation><nlm:aff id="Aff19">Skin and Allergy Hospital, Helsinki University Hospital, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Joos, G" sort="Joos, G" uniqKey="Joos G" first="G." last="Joos">G. Joos</name><affiliation><nlm:aff id="Aff20">Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium</nlm:aff></affiliation></author><author><name sortKey="Khaltaev, N" sort="Khaltaev, N" uniqKey="Khaltaev N" first="N." last="Khaltaev">N. Khaltaev</name><affiliation><nlm:aff id="Aff13">Global Alliance Against Chronic Respiratory Diseases (GARD), Cape Town, South Africa</nlm:aff></affiliation></author><author><name sortKey="Malva, J" sort="Malva, J" uniqKey="Malva J" first="J." last="Malva">J. Malva</name><affiliation><nlm:aff id="Aff21">Faculty of Medicine, University of Coimbra, Coimbra, Portugal</nlm:aff></affiliation><affiliation><nlm:aff id="Aff22">Ageing@Coimbra Reference Site, Coimbra, Portugal</nlm:aff></affiliation></author><author><name sortKey="Muraro, A" sort="Muraro, A" uniqKey="Muraro A" first="A." last="Muraro">A. Muraro</name><affiliation><nlm:aff id="Aff8">European Academy of Allergy and Clinical Immunology, Zurich, Switzerland</nlm:aff></affiliation><affiliation><nlm:aff id="Aff23">Food Allergy Referral Centre Veneto Region, Department of Women and Child Health, Padua General University Hospital, Padua, Italy</nlm:aff></affiliation></author><author><name sortKey="Nogues, M" sort="Nogues, M" uniqKey="Nogues M" first="M." last="Nogues">M. Nogues</name><affiliation><nlm:aff id="Aff24">Caisse Assurance Retraite et Santé Au Travail Languedoc-Roussillon (CARSAT-LR), 34000 Montpellier, France</nlm:aff></affiliation></author><author><name sortKey="Palkonen, S" sort="Palkonen, S" uniqKey="Palkonen S" first="S." last="Palkonen">S. Palkonen</name><affiliation><nlm:aff id="Aff25">EFA European Federation of Allergy and Airways Diseases Patients’ Associations, Brussels, Belgium</nlm:aff></affiliation></author><author><name sortKey="Pedersen, S" sort="Pedersen, S" uniqKey="Pedersen S" first="S." last="Pedersen">S. Pedersen</name><affiliation><nlm:aff id="Aff26">University of Southern Denmark, Kolding, Denmark</nlm:aff></affiliation></author><author><name sortKey="Robalo Cordeiro, C" sort="Robalo Cordeiro, C" uniqKey="Robalo Cordeiro C" first="C." last="Robalo-Cordeiro">C. Robalo-Cordeiro</name><affiliation><nlm:aff id="Aff27">Centre of Pneumology, Coimbra University Hospital, Coimbra, Portugal</nlm:aff></affiliation></author><author><name sortKey="Samolinski, B" sort="Samolinski, B" uniqKey="Samolinski B" first="B." last="Samolinski">B. Samolinski</name><affiliation><nlm:aff id="Aff28">Department of Prevention of Environmental Hazards and Allergology, Medical University of Warsaw, Warsaw, Poland</nlm:aff></affiliation></author><author><name sortKey="Strandberg, T" sort="Strandberg, T" uniqKey="Strandberg T" first="T." last="Strandberg">T. Strandberg</name><affiliation><nlm:aff id="Aff29">Helsinki University, Helsinki University Hospital, Helsinki, Finland</nlm:aff></affiliation><affiliation><nlm:aff id="Aff30">Center for Life Course Health Research, University of Oulu, Oulu, Finland</nlm:aff></affiliation><affiliation><nlm:aff id="Aff31">European Union GeriatricMedicine Society, EUGMS, Oslo, Norway</nlm:aff></affiliation></author><author><name sortKey="Valiulis, A" sort="Valiulis, A" uniqKey="Valiulis A" first="A." last="Valiulis">A. Valiulis</name><affiliation><nlm:aff id="Aff32">Center of Quality of Life Research, Vilnius University Clinic of Children’s Diseases, Vilnius University Public Health Institute, Vilnius, Lithuania</nlm:aff></affiliation><affiliation><nlm:aff id="Aff33">European Association of Pediatrics (EAP/UEMS-SP), Brussels, Belgium</nlm:aff></affiliation></author><author><name sortKey="Yorgancioglu, A" sort="Yorgancioglu, A" uniqKey="Yorgancioglu A" first="A." last="Yorgancioglu">A. Yorgancioglu</name><affiliation><nlm:aff id="Aff13">Global Alliance Against Chronic Respiratory Diseases (GARD), Cape Town, South Africa</nlm:aff></affiliation><affiliation><nlm:aff id="Aff18">EIP on AHA Commitment for Action, Lisbon, Portugal</nlm:aff></affiliation><affiliation><nlm:aff id="Aff34">Department of Pulmonology, Celal Bayar University, Manisa, Turkey</nlm:aff></affiliation><affiliation><nlm:aff id="Aff35">Turkish Thoracic Society, Antalya, Turkey</nlm:aff></affiliation></author><author><name sortKey="Zuberbier, T" sort="Zuberbier, T" uniqKey="Zuberbier T" first="T." last="Zuberbier">T. Zuberbier</name><affiliation><nlm:aff id="Aff36">Allergy-Centre-Charité at the Department of Dermatology, Charité - Universitätsmedizin Berlin, Berlin, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="Aff37">Secretary General of the Global Allergy and Asthma European Network (GA²LEN), Berlin, Germany</nlm:aff></affiliation></author><author><name sortKey="Bedbrook, A" sort="Bedbrook, A" uniqKey="Bedbrook A" first="A." last="Bedbrook">A. Bedbrook</name><affiliation><nlm:aff id="Aff2">MACVIA-LR, Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc Roussilon, European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier, France</nlm:aff></affiliation></author><author><name sortKey="Aberer, W" sort="Aberer, W" uniqKey="Aberer W" first="W." last="Aberer">W. Aberer</name><affiliation><nlm:aff id="Aff38">Department of Dermatology, Medical University of Graz, Graz, Austria</nlm:aff></affiliation></author><author><name sortKey="Adachi, M" sort="Adachi, M" uniqKey="Adachi M" first="M." last="Adachi">M. Adachi</name><affiliation><nlm:aff id="Aff39">Department of Clinical Research Center, International University of Health and Welfare/Sanno Hospital, Tokyo, Japan</nlm:aff></affiliation></author><author><name sortKey="Agusti, A" sort="Agusti, A" uniqKey="Agusti A" first="A." last="Agusti">A. Agusti</name><affiliation><nlm:aff id="Aff40">Thorax Institute, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain</nlm:aff></affiliation><affiliation><nlm:aff id="Aff41">CIBER Enfermedades Respiratorias, Barcelona, Spain</nlm:aff></affiliation></author><author><name sortKey="Akdis, C A" sort="Akdis, C A" uniqKey="Akdis C" first="C. A." last="Akdis">C. A. Akdis</name><affiliation><nlm:aff id="Aff42">Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland</nlm:aff></affiliation></author><author><name sortKey="Akdis, M" sort="Akdis, M" uniqKey="Akdis M" first="M." last="Akdis">M. Akdis</name><affiliation><nlm:aff id="Aff42">Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland</nlm:aff></affiliation></author><author><name sortKey="Ankri, J" sort="Ankri, J" uniqKey="Ankri J" first="J." last="Ankri">J. Ankri</name><affiliation><nlm:aff id="Aff3">INSERM, VIMA: Ageing and Chronic Diseases, Epidemiological and Public Health Approaches, U1168, Paris, France</nlm:aff></affiliation><affiliation><nlm:aff id="Aff4">UVSQ, UMR-S 1168, Université Versailles St-Quentin-en-Yvelines, Paris, France</nlm:aff></affiliation></author><author><name sortKey="Alonso, A" sort="Alonso, A" uniqKey="Alonso A" first="A." last="Alonso">A. Alonso</name><affiliation><nlm:aff id="Aff40">Thorax Institute, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain</nlm:aff></affiliation><affiliation><nlm:aff id="Aff41">CIBER Enfermedades Respiratorias, Barcelona, Spain</nlm:aff></affiliation></author><author><name sortKey="Annesi Maesano, I" sort="Annesi Maesano, I" uniqKey="Annesi Maesano I" first="I." last="Annesi-Maesano">I. Annesi-Maesano</name><affiliation><nlm:aff id="Aff43">EPAR U707 INSERM, Paris, France</nlm:aff></affiliation><affiliation><nlm:aff id="Aff331">EPAR UMR-S UPMC, Paris VI, Paris, France</nlm:aff></affiliation></author><author><name sortKey="Ansotegui, I J" sort="Ansotegui, I J" uniqKey="Ansotegui I" first="I. J." last="Ansotegui">I. J. Ansotegui</name><affiliation><nlm:aff id="Aff44">Department of Allergy and Immunology, Hospital Quirón Bizkaia, Erandio, Spain</nlm:aff></affiliation></author><author><name sortKey="Anto, J M" sort="Anto, J M" uniqKey="Anto J" first="J. M." last="Anto">J. M. Anto</name><affiliation><nlm:aff id="Aff45">Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain</nlm:aff></affiliation><affiliation><nlm:aff id="Aff46">Hospital del Mar Research Institute (IMIM), Barcelona, Spain</nlm:aff></affiliation><affiliation><nlm:aff id="Aff47">CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain</nlm:aff></affiliation><affiliation><nlm:aff id="Aff48">Department of Experimental and Health Sciences, University of Pompeu Fabra (UPF), Barcelona, Spain</nlm:aff></affiliation></author><author><name sortKey="Arnavielhe, S" sort="Arnavielhe, S" uniqKey="Arnavielhe S" first="S." last="Arnavielhe">S. Arnavielhe</name><affiliation><nlm:aff id="Aff49">Digi Health, Montpellier, France</nlm:aff></affiliation></author><author><name sortKey="Arshad, H" sort="Arshad, H" uniqKey="Arshad H" first="H." last="Arshad">H. Arshad</name><affiliation><nlm:aff id="Aff50">David Hide Asthma and Allergy Research Centre, Isle of Wight, UK</nlm:aff></affiliation></author><author><name sortKey="Bai, C" sort="Bai, C" uniqKey="Bai C" first="C." last="Bai">C. Bai</name><affiliation><nlm:aff id="Aff51">Shanghai Respiratory Research Institute, Vice President of Respiratory Society, Chinese Medical Association, China and Chinese Alliance Against Lung Cancer, Shanghai, China</nlm:aff></affiliation></author><author><name sortKey="Baiardini, I" sort="Baiardini, I" uniqKey="Baiardini I" first="I." last="Baiardini">I. Baiardini</name><affiliation><nlm:aff id="Aff52">Allergy and Respiratory Diseases Clinic, DIMI, IRCCS AOU San Martino-IST, University of Genoa, Genoa, Italy</nlm:aff></affiliation></author><author><name sortKey="Bachert, C" sort="Bachert, C" uniqKey="Bachert C" first="C." last="Bachert">C. Bachert</name><affiliation><nlm:aff id="Aff53">Upper Airways Research Laboratory, ENT Department, Ghent University Hospital, Ghent, Belgium</nlm:aff></affiliation></author><author><name sortKey="Baigenzhin, A K" sort="Baigenzhin, A K" uniqKey="Baigenzhin A" first="A. K." last="Baigenzhin">A. K. Baigenzhin</name><affiliation><nlm:aff id="Aff54">EuroAsian Respiratory Society, Astana City, Kazakhstan</nlm:aff></affiliation></author><author><name sortKey="Barbara, C" sort="Barbara, C" uniqKey="Barbara C" first="C." last="Barbara">C. Barbara</name><affiliation><nlm:aff id="Aff55">Faculdade de Medicina de Lisboa, Portuguese National Programme for Respiratory Diseases (PNDR), Lisbon, Portugal</nlm:aff></affiliation></author><author><name sortKey="Bateman, E D" sort="Bateman, E D" uniqKey="Bateman E" first="E. D." last="Bateman">E. D. Bateman</name><affiliation><nlm:aff id="Aff56">Department of Medicine, University of Cape Town, Cape Town, South Africa</nlm:aff></affiliation></author><author><name sortKey="Beghe, B" sort="Beghe, B" uniqKey="Beghe B" first="B." last="Beghé">B. Beghé</name><affiliation><nlm:aff id="Aff57">Section of Respiratory Disease, Department of Oncology, Haematology and Respiratory Diseases, University of Modena and Reggio Emilia, Modena, Italy</nlm:aff></affiliation></author><author><name sortKey="Kheder, A Ben" sort="Kheder, A Ben" uniqKey="Kheder A" first="A. Ben" last="Kheder">A. Ben Kheder</name><affiliation><nlm:aff id="Aff58">Service de pneumologie IV, hôpital Abderrahman Mami, Ariana, 2080 Tunis, Tunisia</nlm:aff></affiliation></author><author><name sortKey="Bennoor, K S" sort="Bennoor, K S" uniqKey="Bennoor K" first="K. S." last="Bennoor">K. S. Bennoor</name><affiliation><nlm:aff id="Aff59">Department of Respiratory Medicine, National Institute of Diseases of the Chest and Hospital, Dhaka, Bangladesh</nlm:aff></affiliation></author><author><name sortKey="Benson, M" sort="Benson, M" uniqKey="Benson M" first="M." last="Benson">M. Benson</name><affiliation><nlm:aff id="Aff60">Centre for Individualized Medicine, Department of Pediatrics, Faculty of Medicine, LInköping University, Linköping, Sweden</nlm:aff></affiliation></author><author><name sortKey="Bergmann, K C" sort="Bergmann, K C" uniqKey="Bergmann K" first="K. C." last="Bergmann">K. C. Bergmann</name><affiliation><nlm:aff id="Aff36">Allergy-Centre-Charité at the Department of Dermatology, Charité - Universitätsmedizin Berlin, Berlin, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="Aff37">Secretary General of the Global Allergy and Asthma European Network (GA²LEN), Berlin, Germany</nlm:aff></affiliation></author><author><name sortKey="Bieber, T" sort="Bieber, T" uniqKey="Bieber T" first="T." last="Bieber">T. Bieber</name><affiliation><nlm:aff id="Aff61">Department of Dermatology and Allergy, Rheinische Friedrich-Wilhelms-University Bonn, Bonn, Germany</nlm:aff></affiliation></author><author><name sortKey="Bindslev Jensen, C" sort="Bindslev Jensen, C" uniqKey="Bindslev Jensen C" first="C." last="Bindslev-Jensen">C. Bindslev-Jensen</name><affiliation><nlm:aff id="Aff62">Department of Dermatology and Allergy Centre, Odense University Hospital, Odense, Denmark</nlm:aff></affiliation></author><author><name sortKey="Bjermer, L" sort="Bjermer, L" uniqKey="Bjermer L" first="L." last="Bjermer">L. Bjermer</name><affiliation><nlm:aff id="Aff63">Department of Respiratory Medicine and Allergology, University Hospital, Lund, Sweden</nlm:aff></affiliation></author><author><name sortKey="Blain, H" sort="Blain, H" uniqKey="Blain H" first="H." last="Blain">H. Blain</name><affiliation><nlm:aff id="Aff64">Department of Geriatrics, Montpellier University Hospital, Montpellier, France</nlm:aff></affiliation><affiliation><nlm:aff id="Aff65">EA 2991, Euromov, University Montpellier, Montpellier, France</nlm:aff></affiliation></author><author><name sortKey="Blasi, F" sort="Blasi, F" uniqKey="Blasi F" first="F." last="Blasi">F. Blasi</name><affiliation><nlm:aff id="Aff66">Department of Pathophysiology and Transplantation, IRCCS Fondazione Ca’Granda Ospedale Maggiore Policlinico, University of Milan, Via F. Sforza 35, Milan, Italy</nlm:aff></affiliation></author><author><name sortKey="Boner, A L" sort="Boner, A L" uniqKey="Boner A" first="A. L." last="Boner">A. L. Boner</name><affiliation><nlm:aff id="Aff67">Pediatric Department, University of Verona Hospital, Verona, Italy</nlm:aff></affiliation></author><author><name sortKey="Bonini, M" sort="Bonini, M" uniqKey="Bonini M" first="M." last="Bonini">M. Bonini</name><affiliation><nlm:aff id="Aff68">Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy</nlm:aff></affiliation></author><author><name sortKey="Bonini, S" sort="Bonini, S" uniqKey="Bonini S" first="S." last="Bonini">S. Bonini</name><affiliation><nlm:aff id="Aff69">Second University of Naples and Institute of Translational Medicine, Italian National Research Council, Naples, Italy</nlm:aff></affiliation></author><author><name sortKey="Bosnic Anticevitch, S" sort="Bosnic Anticevitch, S" uniqKey="Bosnic Anticevitch S" first="S." last="Bosnic-Anticevitch">S. Bosnic-Anticevitch</name><affiliation><nlm:aff id="Aff70">Woolcock Institute of Medical Research, University of Sydney and Sydney Local Health District, Glebe, NSW Australia</nlm:aff></affiliation></author><author><name sortKey="Boulet, L P" sort="Boulet, L P" uniqKey="Boulet L" first="L. P." last="Boulet">L. P. Boulet</name><affiliation><nlm:aff id="Aff71">Quebec Heart and Lung Institute, Laval University, Québec City, QC Canada</nlm:aff></affiliation></author><author><name sortKey="Bourret, R" sort="Bourret, R" uniqKey="Bourret R" first="R." last="Bourret">R. Bourret</name><affiliation><nlm:aff id="Aff72">Directeur Général Adjoint, Montpellier University Hospital, Montpellier, France</nlm:aff></affiliation></author><author><name sortKey="Bousquet, P J" sort="Bousquet, P J" uniqKey="Bousquet P" first="P. J." last="Bousquet">P. J. Bousquet</name><affiliation><nlm:aff id="Aff43">EPAR U707 INSERM, Paris, France</nlm:aff></affiliation></author><author><name sortKey="Braido, F" sort="Braido, F" uniqKey="Braido F" first="F." last="Braido">F. Braido</name><affiliation><nlm:aff id="Aff52">Allergy and Respiratory Diseases Clinic, DIMI, IRCCS AOU San Martino-IST, University of Genoa, Genoa, Italy</nlm:aff></affiliation></author><author><name sortKey="Briggs, A H" sort="Briggs, A H" uniqKey="Briggs A" first="A. H." last="Briggs">A. H. Briggs</name><affiliation><nlm:aff id="Aff73">Health Economics and Health Technology Assessment, Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK</nlm:aff></affiliation></author><author><name sortKey="Brightling, C E" sort="Brightling, C E" uniqKey="Brightling C" first="C. E." last="Brightling">C. E. Brightling</name><affiliation><nlm:aff id="Aff74">Respiratory Biomedical Unit, Institute of Lung Health, University Hospitals of Leicester NHS Trust, Leicestershire, UK</nlm:aff></affiliation><affiliation><nlm:aff id="Aff75">Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, UK</nlm:aff></affiliation></author><author><name sortKey="Brozek, J" sort="Brozek, J" uniqKey="Brozek J" first="J." last="Brozek">J. Brozek</name><affiliation><nlm:aff id="Aff76">Department of Clinical Epidemiology and Biostatistics, McMaster University, HSC Room 2C16, 1280 Main Street West Hamilton, Hamilton, Canada</nlm:aff></affiliation></author><author><name sortKey="Buhl, R" sort="Buhl, R" uniqKey="Buhl R" first="R." last="Buhl">R. Buhl</name><affiliation><nlm:aff id="Aff77">Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Mainz, Germany</nlm:aff></affiliation></author><author><name sortKey="Burney, P G" sort="Burney, P G" uniqKey="Burney P" first="P. G." last="Burney">P. G. Burney</name><affiliation><nlm:aff id="Aff78">National Heart and Lung Institute, Imperial College, London, London, UK</nlm:aff></affiliation><affiliation><nlm:aff id="Aff79">Wellcome Centre for Global Health, Imperial College, London, London, UK</nlm:aff></affiliation><affiliation><nlm:aff id="Aff80">MRC-PHE Centre for Environment and Health, Imperial College, London, London, UK</nlm:aff></affiliation></author><author><name sortKey="Bush, A" sort="Bush, A" uniqKey="Bush A" first="A." last="Bush">A. Bush</name><affiliation><nlm:aff id="Aff81">Imperial College and Royal Brompton Hospital, London, UK</nlm:aff></affiliation></author><author><name sortKey="Caballero Fonseca, F" sort="Caballero Fonseca, F" uniqKey="Caballero Fonseca F" first="F." last="Caballero-Fonseca">F. Caballero-Fonseca</name><affiliation><nlm:aff id="Aff82">Centro Medico Docente La Trinidad, Caracas, Venezuela</nlm:aff></affiliation></author><author><name sortKey="Caimmi, D" sort="Caimmi, D" uniqKey="Caimmi D" first="D." last="Caimmi">D. Caimmi</name><affiliation><nlm:aff id="Aff83">Department of Respiratory Diseases, Montpellier University Hospital, Montpellier, France</nlm:aff></affiliation></author><author><name sortKey="Calderon, M A" sort="Calderon, M A" uniqKey="Calderon M" first="M. A." last="Calderon">M. A. Calderon</name><affiliation><nlm:aff id="Aff84">National Heart and Lung Institute, Imperial College London, Royal Brompton Hospital NHS, London, UK</nlm:aff></affiliation></author><author><name sortKey="Calverley, P M" sort="Calverley, P M" uniqKey="Calverley P" first="P. M." last="Calverley">P. M. Calverley</name><affiliation><nlm:aff id="Aff85">Institute of Ageing and Chronic Disease, University of Liverpool and University Hospital Aintree, Liverpool, UK</nlm:aff></affiliation></author><author><name sortKey="Camargos, P A M" sort="Camargos, P A M" uniqKey="Camargos P" first="P. A. M." last="Camargos">P. A. M. Camargos</name><affiliation><nlm:aff id="Aff86">Department of Pediatrics, Medical School, Federal University of Minas Gerais, Belo Horizonte, Brazil</nlm:aff></affiliation></author><author><name sortKey="Canonica, G W" sort="Canonica, G W" uniqKey="Canonica G" first="G. W." last="Canonica">G. W. Canonica</name><affiliation><nlm:aff id="Aff52">Allergy and Respiratory Diseases Clinic, DIMI, IRCCS AOU San Martino-IST, University of Genoa, Genoa, Italy</nlm:aff></affiliation></author><author><name sortKey="Camuzat, T" sort="Camuzat, T" uniqKey="Camuzat T" first="T." last="Camuzat">T. Camuzat</name><affiliation><nlm:aff id="Aff87">Région Languedoc Roussillon, Montpellier, France</nlm:aff></affiliation></author><author><name sortKey="Carlsen, K H" sort="Carlsen, K H" uniqKey="Carlsen K" first="K. H." last="Carlsen">K. H. Carlsen</name><affiliation><nlm:aff id="Aff88">Department of Paediatrics, Oslo University Hospital and University of Oslo, Oslo, Norway</nlm:aff></affiliation></author><author><name sortKey="Carr, W" sort="Carr, W" uniqKey="Carr W" first="W." last="Carr">W. Carr</name><affiliation><nlm:aff id="Aff89">Allergy and Asthma Associates of Southern California, Mission Viejo, CA USA</nlm:aff></affiliation></author><author><name sortKey="Carriazo, A" sort="Carriazo, A" uniqKey="Carriazo A" first="A." last="Carriazo">A. Carriazo</name><affiliation><nlm:aff id="Aff90">Regional Ministry of Equality, Health and Social Policies of Andalusia, Seville, Spain</nlm:aff></affiliation></author><author><name sortKey="Casale, T" sort="Casale, T" uniqKey="Casale T" first="T." last="Casale">T. Casale</name><affiliation><nlm:aff id="Aff91">Division of Allergy/Immunology, University of South Florida, Tampa, FL USA</nlm:aff></affiliation></author><author><name sortKey="Cepeda Sarabia, A M" sort="Cepeda Sarabia, A M" uniqKey="Cepeda Sarabia A" first="A. M." last="Cepeda Sarabia">A. M. Cepeda Sarabia</name><affiliation><nlm:aff id="Aff92">Allergy and Immunology Laboratory, Metropolitan University, Simon Bolivar University, Barranquilla, Colombia</nlm:aff></affiliation><affiliation><nlm:aff id="Aff93">Asma e Immunologia, SLaai, Sociedad Latinoamericana de Allergia, Barranquilla, Colombia</nlm:aff></affiliation></author><author><name sortKey="Chatzi, L" sort="Chatzi, L" uniqKey="Chatzi L" first="L." last="Chatzi">L. Chatzi</name><affiliation><nlm:aff id="Aff94">Department of Social Medicine, Faculty of Medicine, University of Crete, PO Box 2208, Heraklion, 71003 Crete Greece</nlm:aff></affiliation></author><author><name sortKey="Chen, Y Z" sort="Chen, Y Z" uniqKey="Chen Y" first="Y. Z." last="Chen">Y. Z. Chen</name><affiliation><nlm:aff id="Aff95">National Cooperative Group of Paediatric Research on Asthma, Asthma Clinic and Education Center of the Capital Institute of Pediatrics, Peking and Center for Asthma Research and Education, Beijing, China</nlm:aff></affiliation></author><author><name sortKey="Chiron, R" sort="Chiron, R" uniqKey="Chiron R" first="R." last="Chiron">R. Chiron</name><affiliation><nlm:aff id="Aff83">Department of Respiratory Diseases, Montpellier University Hospital, Montpellier, France</nlm:aff></affiliation></author><author><name sortKey="Chkhartishvili, E" sort="Chkhartishvili, E" uniqKey="Chkhartishvili E" first="E." last="Chkhartishvili">E. Chkhartishvili</name><affiliation><nlm:aff id="Aff96">Chachava Clinic, David Tvildiani Medical University-AIETI Medical School, Grigol Robakidze University, Tbilisi, Georgia</nlm:aff></affiliation></author><author><name sortKey="Chuchalin, A G" sort="Chuchalin, A G" uniqKey="Chuchalin A" first="A. G." last="Chuchalin">A. G. Chuchalin</name><affiliation><nlm:aff id="Aff17">GARD Executive Committee, Bahia, Brazil</nlm:aff></affiliation><affiliation><nlm:aff id="Aff97">Pulmonolory Research Institute FMBA, Moscow, Russia</nlm:aff></affiliation></author><author><name sortKey="Chung, K F" sort="Chung, K F" uniqKey="Chung K" first="K. F." last="Chung">K. F. Chung</name><affiliation><nlm:aff id="Aff98">National Heart and Lung Institute, Imperial College, London, London, UK</nlm:aff></affiliation></author><author><name sortKey="Ciprandi, G" sort="Ciprandi, G" uniqKey="Ciprandi G" first="G." last="Ciprandi">G. Ciprandi</name><affiliation><nlm:aff id="Aff99">Medicine Department, IRCCS-Azienda Ospedaliera Universitaria San Martino, Genoa, Italy</nlm:aff></affiliation></author><author><name sortKey="Cirule, I" sort="Cirule, I" uniqKey="Cirule I" first="I." last="Cirule">I. Cirule</name><affiliation><nlm:aff id="Aff100">Latvian Allergy Association, Riga, Latvia</nlm:aff></affiliation></author><author><name sortKey="Cox, L" sort="Cox, L" uniqKey="Cox L" first="L." last="Cox">L. Cox</name><affiliation><nlm:aff id="Aff101">Department of Medicine, Nova Southeastern University, Davie, FL USA</nlm:aff></affiliation></author><author><name sortKey="Costa, D J" sort="Costa, D J" uniqKey="Costa D" first="D. J." last="Costa">D. J. Costa</name><affiliation><nlm:aff id="Aff2">MACVIA-LR, Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc Roussilon, European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier, France</nlm:aff></affiliation><affiliation><nlm:aff id="Aff12">Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Custovic, A" sort="Custovic, A" uniqKey="Custovic A" first="A." last="Custovic">A. Custovic</name><affiliation><nlm:aff id="Aff102">Department of Paediatrics, Imperial College London, London, UK</nlm:aff></affiliation></author><author><name sortKey="Dahl, R" sort="Dahl, R" uniqKey="Dahl R" first="R." last="Dahl">R. Dahl</name><affiliation><nlm:aff id="Aff62">Department of Dermatology and Allergy Centre, Odense University Hospital, Odense, Denmark</nlm:aff></affiliation></author><author><name sortKey="Dahlen, S E" sort="Dahlen, S E" uniqKey="Dahlen S" first="S. E." last="Dahlen">S. E. Dahlen</name><affiliation><nlm:aff id="Aff103">The Centre for Allergy Research, The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden</nlm:aff></affiliation></author><author><name sortKey="Darsow, U" sort="Darsow, U" uniqKey="Darsow U" first="U." last="Darsow">U. Darsow</name><affiliation><nlm:aff id="Aff104">Department of Dermatology and Allergy, Technische Universität München, Munich, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="Aff105">ZAUM-Center for Allergy and Environment, Helmholtz Center Munich, Technische Universität München, Munich, Germany</nlm:aff></affiliation></author><author><name sortKey="De Carlo, G" sort="De Carlo, G" uniqKey="De Carlo G" first="G." last="De Carlo">G. De Carlo</name><affiliation><nlm:aff id="Aff25">EFA European Federation of Allergy and Airways Diseases Patients’ Associations, Brussels, Belgium</nlm:aff></affiliation></author><author><name sortKey="De Blay, F" sort="De Blay, F" uniqKey="De Blay F" first="F." last="De Blay">F. De Blay</name><affiliation><nlm:aff id="Aff106">Allergy Division, Chest Disease Department, University Hospital of Strasbourg, Strasbourg, France</nlm:aff></affiliation></author><author><name sortKey="Dedeu, T" sort="Dedeu, T" uniqKey="Dedeu T" first="T." last="Dedeu">T. Dedeu</name><affiliation><nlm:aff id="Aff107">EUREGHA, European Regional and Local Health Association, Brussels, Belgium</nlm:aff></affiliation><affiliation><nlm:aff id="Aff108">University of Edinburgh, Edinburgh, UK</nlm:aff></affiliation></author><author><name sortKey="Deleanu, D" sort="Deleanu, D" uniqKey="Deleanu D" first="D." last="Deleanu">D. Deleanu</name><affiliation><nlm:aff id="Aff109">Allergology and Immunology Discipline, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania</nlm:aff></affiliation></author><author><name sortKey="De Manuel Keenoy, E" sort="De Manuel Keenoy, E" uniqKey="De Manuel Keenoy E" first="E." last="De Manuel Keenoy">E. De Manuel Keenoy</name><affiliation><nlm:aff id="Aff110">Kronikgune, Bilbao, Basque Region Spain</nlm:aff></affiliation></author><author><name sortKey="Demoly, P" sort="Demoly, P" uniqKey="Demoly P" first="P." last="Demoly">P. Demoly</name><affiliation><nlm:aff id="Aff43">EPAR U707 INSERM, Paris, France</nlm:aff></affiliation><affiliation><nlm:aff id="Aff83">Department of Respiratory Diseases, Montpellier University Hospital, Montpellier, France</nlm:aff></affiliation></author><author><name sortKey="Denburg, J A" sort="Denburg, J A" uniqKey="Denburg J" first="J. A." last="Denburg">J. A. Denburg</name><affiliation><nlm:aff id="Aff111">Department of Medicine, Division of Clinical Immunology and Allergy, McMaster University, Hamilton, ON Canada</nlm:aff></affiliation></author><author><name sortKey="Devillier, P" sort="Devillier, P" uniqKey="Devillier P" first="P." last="Devillier">P. Devillier</name><affiliation><nlm:aff id="Aff112">Laboratoire de Pharmacologie Respiratoire UPRES EA220, Hôpital Foch, Suresnes Université Versailles Saint-Quentin, Suresnes, France</nlm:aff></affiliation></author><author><name sortKey="Didier, A" sort="Didier, A" uniqKey="Didier A" first="A." last="Didier">A. Didier</name><affiliation><nlm:aff id="Aff113">Respiratory Diseases Department, Rangueil-Larrey Hospital, Toulouse, France</nlm:aff></affiliation></author><author><name sortKey="Dinh Xuan, A T" sort="Dinh Xuan, A T" uniqKey="Dinh Xuan A" first="A. T." last="Dinh-Xuan">A. T. Dinh-Xuan</name><affiliation><nlm:aff id="Aff114">Service de physiologie respiratoire, Hôpital Cochin, Université Paris-Descartes, Assistance publique-Hôpitaux de Paris, Paris, France</nlm:aff></affiliation></author><author><name sortKey="Djukanovic, R" sort="Djukanovic, R" uniqKey="Djukanovic R" first="R." last="Djukanovic">R. Djukanovic</name><affiliation><nlm:aff id="Aff115">NIHR Southampton Respiratory Biomedical Research Unit, Faculty of Medicine, University Southampton, Southampton, UK</nlm:aff></affiliation></author><author><name sortKey="Dokic, D" sort="Dokic, D" uniqKey="Dokic D" first="D." last="Dokic">D. Dokic</name><affiliation><nlm:aff id="Aff116">Medical Faculty Skopje, University Clinic of Pulmology and Allergy, Skopje, Republic Macedonia</nlm:aff></affiliation></author><author><name sortKey="Douagui, H" sort="Douagui, H" uniqKey="Douagui H" first="H." last="Douagui">H. Douagui</name><affiliation><nlm:aff id="Aff117">Service de Pneumo-Allergologie, Centre Hospitalo-Universitaire de Béni-Messous, Algers, Algeria</nlm:aff></affiliation></author><author><name sortKey="Dray, G" sort="Dray, G" uniqKey="Dray G" first="G." last="Dray">G. Dray</name><affiliation><nlm:aff id="Aff118">Ecole des Mines, Alès, France</nlm:aff></affiliation></author><author><name sortKey="Dubakiene, R" sort="Dubakiene, R" uniqKey="Dubakiene R" first="R." last="Dubakiene">R. Dubakiene</name><affiliation><nlm:aff id="Aff119">Medical Faculty, Vilnius University, Vilnius, Lithuania</nlm:aff></affiliation></author><author><name sortKey="Durham, S R" sort="Durham, S R" uniqKey="Durham S" first="S. R." last="Durham">S. R. Durham</name><affiliation><nlm:aff id="Aff120">Allergy and Clinical Immunology Section, National Heart and Lung Institute, Imperial College London, London, UK</nlm:aff></affiliation></author><author><name sortKey="Dykewicz, M S" sort="Dykewicz, M S" uniqKey="Dykewicz M" first="M. S." last="Dykewicz">M. S. Dykewicz</name><affiliation><nlm:aff id="Aff121">Section of Allergy and Immunology, Saint Louis University School of Medicine, Saint Louis, MO USA</nlm:aff></affiliation></author><author><name sortKey="El Gamal, Y" sort="El Gamal, Y" uniqKey="El Gamal Y" first="Y." last="El-Gamal">Y. El-Gamal</name><affiliation><nlm:aff id="Aff122">Pediatric Allergy and Immunology Unit, Ain Shams University, Cairo, Egypt</nlm:aff></affiliation></author><author><name sortKey="Emuzyte, R" sort="Emuzyte, R" uniqKey="Emuzyte R" first="R." last="Emuzyte">R. Emuzyte</name><affiliation><nlm:aff id="Aff123">Clinic of Children’s Diseases, Faculty of Medicine, Vilnius University, Vilnius, Lithuania</nlm:aff></affiliation></author><author><name sortKey="Fabbri, L M" sort="Fabbri, L M" uniqKey="Fabbri L" first="L. M." last="Fabbri">L. M. Fabbri</name><affiliation><nlm:aff id="Aff124">Modena University, Modena, Italy</nlm:aff></affiliation></author><author><name sortKey="Fletcher, M" sort="Fletcher, M" uniqKey="Fletcher M" first="M." last="Fletcher">M. Fletcher</name><affiliation><nlm:aff id="Aff125">Education for Health, Warwick, UK</nlm:aff></affiliation></author><author><name sortKey="Fiocchi, A" sort="Fiocchi, A" uniqKey="Fiocchi A" first="A." last="Fiocchi">A. Fiocchi</name><affiliation><nlm:aff id="Aff126">Division of Allergy, Department of Pediatric Medicine, The Bambino Gesù Children’s Research Hospital Holy See, Rome, Italy</nlm:aff></affiliation></author><author><name sortKey="Fink Wagner, A" sort="Fink Wagner, A" uniqKey="Fink Wagner A" first="A." last="Fink Wagner">A. Fink Wagner</name><affiliation><nlm:aff id="Aff127">Global Allergy and Asthma Platform (GAAPP), Altgasse 8-10, 1130 Vienna, Austria</nlm:aff></affiliation></author><author><name sortKey="Fonseca, J" sort="Fonseca, J" uniqKey="Fonseca J" first="J." last="Fonseca">J. Fonseca</name><affiliation><nlm:aff id="Aff128">Center for Health Technology and Services Research - CINTESIS, Faculdade de Medicina, Universidade do Porto, Porto, Portugal</nlm:aff></affiliation><affiliation><nlm:aff id="Aff129">Allergy Unit, CUF Porto Instituto & Hospital, Porto, Portugal</nlm:aff></affiliation></author><author><name sortKey="Fokkens, W J" sort="Fokkens, W J" uniqKey="Fokkens W" first="W. J." last="Fokkens">W. J. Fokkens</name><affiliation><nlm:aff id="Aff130">Department of Otorhinolaryngology, Academic Medical Centre, Amsterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Forastiere, F" sort="Forastiere, F" uniqKey="Forastiere F" first="F." last="Forastiere">F. Forastiere</name><affiliation><nlm:aff id="Aff131">Department of Epidemiology, Regional Health Service Lazio Region, Rome, Italy</nlm:aff></affiliation></author><author><name sortKey="Frith, P" sort="Frith, P" uniqKey="Frith P" first="P." last="Frith">P. Frith</name><affiliation><nlm:aff id="Aff132">Repatriation General Hospital, Adelaide, SOUTH AUSTRALIA Australia</nlm:aff></affiliation></author><author><name sortKey="Gaga, M" sort="Gaga, M" uniqKey="Gaga M" first="M." last="Gaga">M. Gaga</name><affiliation><nlm:aff id="Aff133">Athens Chest Hospital, Athens, Greece</nlm:aff></affiliation></author><author><name sortKey="Gamkrelidze, A" sort="Gamkrelidze, A" uniqKey="Gamkrelidze A" first="A." last="Gamkrelidze">A. Gamkrelidze</name><affiliation><nlm:aff id="Aff134">National Center for Disease Control and Public Health of Georgia, Tbilisi, Georgia</nlm:aff></affiliation></author><author><name sortKey="Garces, J" sort="Garces, J" uniqKey="Garces J" first="J." last="Garces">J. Garces</name><affiliation><nlm:aff id="Aff135">Polibienestar Research Institute, University of Valencia, Valencia, Spain</nlm:aff></affiliation></author><author><name sortKey="Garcia Aymerich, J" sort="Garcia Aymerich, J" uniqKey="Garcia Aymerich J" first="J." last="Garcia-Aymerich">J. Garcia-Aymerich</name><affiliation><nlm:aff id="Aff45">Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain</nlm:aff></affiliation><affiliation><nlm:aff id="Aff46">Hospital del Mar Research Institute (IMIM), Barcelona, Spain</nlm:aff></affiliation><affiliation><nlm:aff id="Aff47">CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain</nlm:aff></affiliation><affiliation><nlm:aff id="Aff48">Department of Experimental and Health Sciences, University of Pompeu Fabra (UPF), Barcelona, Spain</nlm:aff></affiliation></author><author><name sortKey="Gemicio Lu, B" sort="Gemicio Lu, B" uniqKey="Gemicio Lu B" first="B." last="Gemicio Lu">B. Gemicio Lu</name><affiliation><nlm:aff id="Aff136">Department of Pulmonary Diseases, Cerrahpasa Faculty of Medicine, Istanbul University, Istanbul, Turkey</nlm:aff></affiliation></author><author><name sortKey="Gereda, J E" sort="Gereda, J E" uniqKey="Gereda J" first="J. E." last="Gereda">J. E. Gereda</name><affiliation><nlm:aff id="Aff137">Allergy and Immunology Division, Clinica Ricardo Palma, Lima, Peru</nlm:aff></affiliation></author><author><name sortKey="Gonzalez Diaz, S" sort="Gonzalez Diaz, S" uniqKey="Gonzalez Diaz S" first="S." last="González Diaz">S. González Diaz</name><affiliation><nlm:aff id="Aff138">Universidad Autónoma de Nuevo León, San Nicolás De La Garza, Mexico</nlm:aff></affiliation></author><author><name sortKey="Gotua, M" sort="Gotua, M" uniqKey="Gotua M" first="M." last="Gotua">M. Gotua</name><affiliation><nlm:aff id="Aff139">Center of Allergy and Immunology, Georgian Association of Allergology and Clinical Immunology, Tbilisi, Georgia</nlm:aff></affiliation></author><author><name sortKey="Grisle, I" sort="Grisle, I" uniqKey="Grisle I" first="I." last="Grisle">I. Grisle</name><affiliation><nlm:aff id="Aff140">Latvian Association of Allergists, Center of Tuberculosis and Lung Diseases, Riga, Latvia</nlm:aff></affiliation></author><author><name sortKey="Grouse, L" sort="Grouse, L" uniqKey="Grouse L" first="L." last="Grouse">L. Grouse</name><affiliation><nlm:aff id="Aff141">Faculty of the Department of Neurology, University of Washington School of Medicine, St. Louis, MO USA</nlm:aff></affiliation></author><author><name sortKey="Gutter, Z" sort="Gutter, Z" uniqKey="Gutter Z" first="Z." last="Gutter">Z. Gutter</name><affiliation><nlm:aff id="Aff142">University Hospital Olomouc – National eHealth Centre, Olomouc, Czech Republic</nlm:aff></affiliation></author><author><name sortKey="Guzman, M A" sort="Guzman, M A" uniqKey="Guzman M" first="M. A." last="Guzmán">M. A. Guzmán</name><affiliation><nlm:aff id="Aff143">Immunology and Allergy Division, Clinical Hospital, University of Chile, Santiago, Chile</nlm:aff></affiliation></author><author><name sortKey="Heaney, L G" sort="Heaney, L G" uniqKey="Heaney L" first="L. G." last="Heaney">L. G. Heaney</name><affiliation><nlm:aff id="Aff144">Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University Belfast, Belfast, UK</nlm:aff></affiliation></author><author><name sortKey="Hellquist Dahl, B" sort="Hellquist Dahl, B" uniqKey="Hellquist Dahl B" first="B." last="Hellquist-Dahl">B. Hellquist-Dahl</name><affiliation><nlm:aff id="Aff145">Department of Respiratory Diseases, Odense University Hospital, Odense, Denmark</nlm:aff></affiliation></author><author><name sortKey="Henderson, D" sort="Henderson, D" uniqKey="Henderson D" first="D." last="Henderson">D. Henderson</name><affiliation><nlm:aff id="Aff6">EIP on AHA, European Innovation Partnership on Active and Healthy Ageing, Reference Site, Scottish Centre for Telehealth and Telecare, NHS 24, Glasgow, UK</nlm:aff></affiliation></author><author><name sortKey="Hendry, A" sort="Hendry, A" uniqKey="Hendry A" first="A." last="Hendry">A. Hendry</name><affiliation><nlm:aff id="Aff146">NHS Scotland, Edinburgh, Scotland, UK</nlm:aff></affiliation></author><author><name sortKey="Heinrich, J" sort="Heinrich, J" uniqKey="Heinrich J" first="J." last="Heinrich">J. Heinrich</name><affiliation><nlm:aff id="Aff147">Institute of Epidemiology I, German Research Centre for Environmental Health, Helmholtz Zentrum München, Neuherberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Heve, D" sort="Heve, D" uniqKey="Heve D" first="D." last="Heve">D. Heve</name><affiliation><nlm:aff id="Aff2">MACVIA-LR, Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc Roussilon, European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier, France</nlm:aff></affiliation><affiliation><nlm:aff id="Aff148">Agence Régionale de Santé, 34067 Montpellier Cedex 2, France</nlm:aff></affiliation></author><author><name sortKey="Horak, F" sort="Horak, F" uniqKey="Horak F" first="F." last="Horak">F. Horak</name><affiliation><nlm:aff id="Aff149">Vienna Challenge Chamber, Vienna, Austria</nlm:aff></affiliation></author><author><name sortKey="Hourihane, J O B" sort="Hourihane, J O B" uniqKey="Hourihane J" first="J. O B." last="Hourihane">J. O B. Hourihane</name><affiliation><nlm:aff id="Aff150">Department of Paediatrics and Child Health, University College Cork, Cork, Ireland</nlm:aff></affiliation></author><author><name sortKey="Howarth, P" sort="Howarth, P" uniqKey="Howarth P" first="P." last="Howarth">P. Howarth</name><affiliation><nlm:aff id="Aff151">University of Southampton Faculty of Medicine, University Hospital Southampton, Southampton, UK</nlm:aff></affiliation></author><author><name sortKey="Humbert, M" sort="Humbert, M" uniqKey="Humbert M" first="M." last="Humbert">M. Humbert</name><affiliation><nlm:aff id="Aff152">Service de Pneumologie, Hôpital Bicêtre, Inserm UMR_S999, Université Paris-Sud, Le Kremlin Bicêtre, France</nlm:aff></affiliation></author><author><name sortKey="Hyland, M E" sort="Hyland, M E" uniqKey="Hyland M" first="M. E." last="Hyland">M. E. Hyland</name><affiliation><nlm:aff id="Aff153">School of Psychology, Plymouth University, Plymouth, UK</nlm:aff></affiliation></author><author><name sortKey="Illario, M" sort="Illario, M" uniqKey="Illario M" first="M." last="Illario">M. Illario</name><affiliation><nlm:aff id="Aff154">Federico II University Hospital/Campania RS, Naples, Italy</nlm:aff></affiliation></author><author><name sortKey="Ivancevich, J C" sort="Ivancevich, J C" uniqKey="Ivancevich J" first="J. C." last="Ivancevich">J. C. Ivancevich</name><affiliation><nlm:aff id="Aff155">Servicio de Alergia e Immunologia, Clinica Santa Isabel, Buenos Aires, Argentina</nlm:aff></affiliation></author><author><name sortKey="Jardim, J R" sort="Jardim, J R" uniqKey="Jardim J" first="J. R." last="Jardim">J. R. Jardim</name><affiliation><nlm:aff id="Aff156">Universidade Federal de Sao Paulo, São Paulo, Brazil</nlm:aff></affiliation></author><author><name sortKey="Jares, E J" sort="Jares, E J" uniqKey="Jares E" first="E. J." last="Jares">E. J. Jares</name><affiliation><nlm:aff id="Aff157">Libra Foundation, Buenos Aires, Argentina</nlm:aff></affiliation></author><author><name sortKey="Jeandel, C" sort="Jeandel, C" uniqKey="Jeandel C" first="C." last="Jeandel">C. Jeandel</name><affiliation><nlm:aff id="Aff2">MACVIA-LR, Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc Roussilon, European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier, France</nlm:aff></affiliation><affiliation><nlm:aff id="Aff64">Department of Geriatrics, Montpellier University Hospital, Montpellier, France</nlm:aff></affiliation></author><author><name sortKey="Jenkins, C" sort="Jenkins, C" uniqKey="Jenkins C" first="C." last="Jenkins">C. Jenkins</name><affiliation><nlm:aff id="Aff158">The George Institute for Global Health, The University of Sydney, Camperdown, Australia</nlm:aff></affiliation></author><author><name sortKey="Johnston, S L" sort="Johnston, S L" uniqKey="Johnston S" first="S. L." last="Johnston">S. L. Johnston</name><affiliation><nlm:aff id="Aff159">Airway Disease Infection Section, National Heart and Lung Institute, Imperial College, London, London, UK</nlm:aff></affiliation><affiliation><nlm:aff id="Aff160">MRC and Asthma UK Centre in Allergic Mechanisms of Asthma, London, UK</nlm:aff></affiliation></author><author><name sortKey="Jonquet, O" sort="Jonquet, O" uniqKey="Jonquet O" first="O." last="Jonquet">O. Jonquet</name><affiliation><nlm:aff id="Aff161">Medical Commission, Montpellier University Hospital, Montpellier, France</nlm:aff></affiliation></author><author><name sortKey="Julge, K" sort="Julge, K" uniqKey="Julge K" first="K." last="Julge">K. Julge</name><affiliation><nlm:aff id="Aff162">Children’s Clinic of Tartu University Hospital, Tartu, Estonia</nlm:aff></affiliation></author><author><name sortKey="Jung, K S" sort="Jung, K S" uniqKey="Jung K" first="K. S." last="Jung">K. S. Jung</name><affiliation><nlm:aff id="Aff163">Hallym University College of Medicine, Hallym University Sacred Heart Hospital, Gyeonggi-Do, South Korea</nlm:aff></affiliation></author><author><name sortKey="Just, J" sort="Just, J" uniqKey="Just J" first="J." last="Just">J. Just</name><affiliation><nlm:aff id="Aff164">Allergology Department, Centre de l’Asthme et des Allergies, Hôpital d’Enfants Armand-Trousseau (APHP), Paris, France</nlm:aff></affiliation><affiliation><nlm:aff id="Aff165">Sorbonne Universités, UPMC Univ Paris 06, UMR_S 1136, Institut Pierre Louis d’Epidémiologie et de Santé Publique, Equipe EPAR, 75013 Paris, France</nlm:aff></affiliation></author><author><name sortKey="Kaidashev, I" sort="Kaidashev, I" uniqKey="Kaidashev I" first="I." last="Kaidashev">I. Kaidashev</name><affiliation><nlm:aff id="Aff166">Ukrainian Medical Stomatological Academy, Poltava, Ukraine</nlm:aff></affiliation></author><author><name sortKey="Kaitov, M R" sort="Kaitov, M R" uniqKey="Kaitov M" first="M. R." last="Kaitov">M. R. Kaitov</name><affiliation><nlm:aff id="Aff167">Federal Medicobiological Agency, Laboratory of Molecular Immunology, Institute of Immunology, National Research Center, Moscow, Russian Federation</nlm:aff></affiliation></author><author><name sortKey="Kalayci, O" sort="Kalayci, O" uniqKey="Kalayci O" first="O." last="Kalayci">O. Kalayci</name><affiliation><nlm:aff id="Aff168">Pediatric Allergy and Asthma Unit, Hacettepe University School of Medicine, Ankara, Turkey</nlm:aff></affiliation></author><author><name sortKey="Kalyoncu, A F" sort="Kalyoncu, A F" uniqKey="Kalyoncu A" first="A. F." last="Kalyoncu">A. F. Kalyoncu</name><affiliation><nlm:aff id="Aff169">Immunology and Allergy Division, Department of Chest Diseases, School of Medicine, Hacettepe University, Ankara, Turkey</nlm:aff></affiliation></author><author><name sortKey="Keil, T" sort="Keil, T" uniqKey="Keil T" first="T." last="Keil">T. Keil</name><affiliation><nlm:aff id="Aff170">Institute of Social Medicine, Epidemiology and Health Economics, Charité - Universitätsmedizin Berlin, Berlin, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="Aff171">Institute for Clinical Epidemiology and Biometry, University of Würzburg, Würzburg, Germany</nlm:aff></affiliation></author><author><name sortKey="Keith, P K" sort="Keith, P K" uniqKey="Keith P" first="P. K." last="Keith">P. K. Keith</name><affiliation><nlm:aff id="Aff172">Department of Medicine, McMaster University, Health Sciences Centre 3V47, 1280 Main Street West, Hamilton, Canada</nlm:aff></affiliation></author><author><name sortKey="Klimek, L" sort="Klimek, L" uniqKey="Klimek L" first="L." last="Klimek">L. Klimek</name><affiliation><nlm:aff id="Aff173">Center for Rhinology and Allergology, Wiesbaden, Germany</nlm:aff></affiliation></author><author><name sortKey="Koffi N Oran, B" sort="Koffi N Oran, B" uniqKey="Koffi N Oran B" first="B." last="Koffi N Oran">B. Koffi N Oran</name><affiliation><nlm:aff id="Aff174">Société de Pneumologie de Langue Française, Espace francophone de Pneumologie, Paris, France</nlm:aff></affiliation></author><author><name sortKey="Kolek, V" sort="Kolek, V" uniqKey="Kolek V" first="V." last="Kolek">V. Kolek</name><affiliation><nlm:aff id="Aff175">Department of Respiratory Medicine, Faculty of Medicine and Dentistry, University Hospital Olomouc, Olomouc, Czech Republic</nlm:aff></affiliation></author><author><name sortKey="Koppelman, G H" sort="Koppelman, G H" uniqKey="Koppelman G" first="G. H." last="Koppelman">G. H. Koppelman</name><affiliation><nlm:aff id="Aff176">GRIACResearch Institute, Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children’s Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Kowalski, M L" sort="Kowalski, M L" uniqKey="Kowalski M" first="M. L." last="Kowalski">M. L. Kowalski</name><affiliation><nlm:aff id="Aff177">Department of Immunology, Rheumatology and Allergy, Medical University of Lodz, and HARC, Lodz, Poland</nlm:aff></affiliation></author><author><name sortKey="Kull, I" sort="Kull, I" uniqKey="Kull I" first="I." last="Kull">I. Kull</name><affiliation><nlm:aff id="Aff178">Sachs’ Children’s Hospital, Stockholm, Sweden</nlm:aff></affiliation><affiliation><nlm:aff id="Aff179">Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden</nlm:aff></affiliation></author><author><name sortKey="Kuna, P" sort="Kuna, P" uniqKey="Kuna P" first="P." last="Kuna">P. Kuna</name><affiliation><nlm:aff id="Aff180">Division of Internal Medicine, Asthma and Allergy, Barlicki University Hospital, Medical University of Lodz, Lodz, Poland</nlm:aff></affiliation></author><author><name sortKey="Kvedariene, V" sort="Kvedariene, V" uniqKey="Kvedariene V" first="V." last="Kvedariene">V. Kvedariene</name><affiliation><nlm:aff id="Aff181">Clinic of Infectious, Chest Diseases, Dermatology and Allergology, Vilnius University, Vilnius, Lithuania</nlm:aff></affiliation></author><author><name sortKey="Lambrecht, B" sort="Lambrecht, B" uniqKey="Lambrecht B" first="B." last="Lambrecht">B. Lambrecht</name><affiliation><nlm:aff id="Aff182">VIB Inflammation Research Center, Ghent University, Ghent, Belgium</nlm:aff></affiliation></author><author><name sortKey="Lau, S" sort="Lau, S" uniqKey="Lau S" first="S." last="Lau">S. Lau</name><affiliation><nlm:aff id="Aff183">Department for Pediatric Pneumology and Immunology, Charité Medical University, Berlin, Germany</nlm:aff></affiliation></author><author><name sortKey="Larenas Linnemann, D" sort="Larenas Linnemann, D" uniqKey="Larenas Linnemann D" first="D." last="Larenas-Linnemann">D. Larenas-Linnemann</name><affiliation><nlm:aff id="Aff184">Clínica de Alergia, Asma y Pediatría, Hospital Médica Sur, Ciudad De México, Mexico</nlm:aff></affiliation></author><author><name sortKey="Laune, D" sort="Laune, D" uniqKey="Laune D" first="D." last="Laune">D. Laune</name><affiliation><nlm:aff id="Aff49">Digi Health, Montpellier, France</nlm:aff></affiliation></author><author><name sortKey="Le, L T T" sort="Le, L T T" uniqKey="Le L" first="L. T. T." last="Le">L. T. T. Le</name><affiliation><nlm:aff id="Aff185">University of Medicine and Pharmacy, Hochiminh City, Vietnam</nlm:aff></affiliation></author><author><name sortKey="Lieberman, P" sort="Lieberman, P" uniqKey="Lieberman P" first="P." last="Lieberman">P. Lieberman</name><affiliation><nlm:aff id="Aff186">Divisions of Allergy and Immunology, Departments of Internal Medicine and Pediatrics, University of Tennessee College of Medicine, Germantown, TN USA</nlm:aff></affiliation></author><author><name sortKey="Lipworth, B" sort="Lipworth, B" uniqKey="Lipworth B" first="B." last="Lipworth">B. Lipworth</name><affiliation><nlm:aff id="Aff187">Scottish Centre for Respiratory Research, Cardiovascular and Diabetes Medicine, Medical Research Institute, Ninewells Hospital, University of Dundee, Dundee, UK</nlm:aff></affiliation></author><author><name sortKey="Li, J" sort="Li, J" uniqKey="Li J" first="J." last="Li">J. Li</name><affiliation><nlm:aff id="Aff188">State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120 China</nlm:aff></affiliation></author><author><name sortKey="Lodrup Carlsen, K" sort="Lodrup Carlsen, K" uniqKey="Lodrup Carlsen K" first="K." last="Lodrup Carlsen">K. Lodrup Carlsen</name><affiliation><nlm:aff id="Aff189">Department of Paediatrics, Oslo University Hospital, Oslo, Norway</nlm:aff></affiliation><affiliation><nlm:aff id="Aff190">Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway</nlm:aff></affiliation></author><author><name sortKey="Louis, R" sort="Louis, R" uniqKey="Louis R" first="R." last="Louis">R. Louis</name><affiliation><nlm:aff id="Aff191">Department of Pulmonary Medicine, CHU Sart-Tilman, Liege, Belgium</nlm:aff></affiliation></author><author><name sortKey="Macnee, W" sort="Macnee, W" uniqKey="Macnee W" first="W." last="Macnee">W. Macnee</name><affiliation><nlm:aff id="Aff192">Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, UK</nlm:aff></affiliation></author><author><name sortKey="Magard, Y" sort="Magard, Y" uniqKey="Magard Y" first="Y." last="Magard">Y. Magard</name><affiliation><nlm:aff id="Aff193">Service de Pneumo-allergologie, Hôpital Saint-Joseph, Paris, France</nlm:aff></affiliation></author><author><name sortKey="Magnan, A" sort="Magnan, A" uniqKey="Magnan A" first="A." last="Magnan">A. Magnan</name><affiliation><nlm:aff id="Aff194">Service de Pneumologie, UMR INSERM, UMR1087and CNR 6291, l’institut du thorax, University of Nantes, Nantes, France</nlm:aff></affiliation></author><author><name sortKey="Mahboub, B" sort="Mahboub, B" uniqKey="Mahboub B" first="B." last="Mahboub">B. Mahboub</name><affiliation><nlm:aff id="Aff195">Department of Pulmonary Medicine, Rashid Hospital, Dubai, UAE</nlm:aff></affiliation></author><author><name sortKey="Mair, A" sort="Mair, A" uniqKey="Mair A" first="A." last="Mair">A. Mair</name><affiliation><nlm:aff id="Aff196">Scottish Government Health Department, eHealth and Pharmaceuticals, Edinburgh, UK</nlm:aff></affiliation></author><author><name sortKey="Majer, I" sort="Majer, I" uniqKey="Majer I" first="I." last="Majer">I. Majer</name><affiliation><nlm:aff id="Aff197">Department of Respiratory Medicine, University of Bratislava, Bratislava, Slovakia</nlm:aff></affiliation></author><author><name sortKey="Makela, M J" sort="Makela, M J" uniqKey="Makela M" first="M. J." last="Makela">M. J. Makela</name><affiliation><nlm:aff id="Aff19">Skin and Allergy Hospital, Helsinki University Hospital, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Manning, P" sort="Manning, P" uniqKey="Manning P" first="P." last="Manning">P. Manning</name><affiliation><nlm:aff id="Aff198">Department of Medicine (RCSI), Bon Secours Hospital, Glasnevin, Dublin, Ireland</nlm:aff></affiliation></author><author><name sortKey="Mara, S" sort="Mara, S" uniqKey="Mara S" first="S." last="Mara">S. Mara</name><affiliation><nlm:aff id="Aff199">Cardiovascular and Thoracic Department, AOU Città della Salute e della Scienza di Torino, Turin, Italy</nlm:aff></affiliation></author><author><name sortKey="Marshall, G D" sort="Marshall, G D" uniqKey="Marshall G" first="G. D." last="Marshall">G. D. Marshall</name><affiliation><nlm:aff id="Aff200">Division of Clinical Immunology and Allergy, Laboratory of Behavioral Immunology Research, The University of Mississippi Medical Center, Jackson, MS USA</nlm:aff></affiliation></author><author><name sortKey="Masjedi, M R" sort="Masjedi, M R" uniqKey="Masjedi M" first="M. R." last="Masjedi">M. R. Masjedi</name><affiliation><nlm:aff id="Aff201">Respiratory Medicine Research, Shahid Beheshti University of Medical Sciences, Tehran, Iran</nlm:aff></affiliation></author><author><name sortKey="Matignon, P" sort="Matignon, P" uniqKey="Matignon P" first="P." last="Matignon">P. Matignon</name><affiliation><nlm:aff id="Aff202">VingCard Elsafe, Moss, Norway</nlm:aff></affiliation></author><author><name sortKey="Maurer, M" sort="Maurer, M" uniqKey="Maurer M" first="M." last="Maurer">M. Maurer</name><affiliation><nlm:aff id="Aff203">Allergie-Centrum-Charité at the Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Berlin, Germany</nlm:aff></affiliation></author><author><name sortKey="Mavale Manuel, S" sort="Mavale Manuel, S" uniqKey="Mavale Manuel S" first="S." last="Mavale-Manuel">S. Mavale-Manuel</name><affiliation><nlm:aff id="Aff204">Department of Paediatrics, Maputo Central Hospital, Maputo, Mozambique</nlm:aff></affiliation></author><author><name sortKey="Melen, E" sort="Melen, E" uniqKey="Melen E" first="E." last="Melén">E. Melén</name><affiliation><nlm:aff id="Aff205">Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden</nlm:aff></affiliation></author><author><name sortKey="Melo Gomes, E" sort="Melo Gomes, E" uniqKey="Melo Gomes E" first="E." last="Melo-Gomes">E. Melo-Gomes</name><affiliation><nlm:aff id="Aff206">PNDR/Portuguese National Programme for Respiratory Diseases, Lisbon, Portugal</nlm:aff></affiliation></author><author><name sortKey="Meltzer, E O" sort="Meltzer, E O" uniqKey="Meltzer E" first="E. O." last="Meltzer">E. O. Meltzer</name><affiliation><nlm:aff id="Aff207">Allergy and Asthma Medical Group and Research Center, San Diego, CA USA</nlm:aff></affiliation></author><author><name sortKey="Menzies Gow, A" sort="Menzies Gow, A" uniqKey="Menzies Gow A" first="A." last="Menzies-Gow">A. Menzies-Gow</name><affiliation><nlm:aff id="Aff208">Royal Brompton Hospital, London, UK</nlm:aff></affiliation></author><author><name sortKey="Merk, H" sort="Merk, H" uniqKey="Merk H" first="H." last="Merk">H. Merk</name><affiliation><nlm:aff id="Aff209">Hautklinik - Klinik für Dermatologie & Allergologie, Universitätsklinikum der RWTH Aachen, Aachen, Germany</nlm:aff></affiliation></author><author><name sortKey="Michel, J P" sort="Michel, J P" uniqKey="Michel J" first="J. P." last="Michel">J. P. Michel</name><affiliation><nlm:aff id="Aff31">European Union GeriatricMedicine Society, EUGMS, Oslo, Norway</nlm:aff></affiliation></author><author><name sortKey="Miculinic, N" sort="Miculinic, N" uniqKey="Miculinic N" first="N." last="Miculinic">N. Miculinic</name><affiliation><nlm:aff id="Aff210">Croatian Pulmonary Society, Zagreb, Croatia</nlm:aff></affiliation></author><author><name sortKey="Mihaltan, F" sort="Mihaltan, F" uniqKey="Mihaltan F" first="F." last="Mihaltan">F. Mihaltan</name><affiliation><nlm:aff id="Aff211">National Institute of Pneumology M. Nasta, Bucharest, Romania</nlm:aff></affiliation></author><author><name sortKey="Milenkovic, B" sort="Milenkovic, B" uniqKey="Milenkovic B" first="B." last="Milenkovic">B. Milenkovic</name><affiliation><nlm:aff id="Aff212">Faculty of Medicine, University of Belgrade, Belgrade, Serbia</nlm:aff></affiliation><affiliation><nlm:aff id="Aff213">Serbian Association for Asthma and COPD, Belgrade, Serbia</nlm:aff></affiliation></author><author><name sortKey="Mohammad, G M Y" sort="Mohammad, G M Y" uniqKey="Mohammad G" first="G. M. Y." last="Mohammad">G. M. Y. Mohammad</name><affiliation><nlm:aff id="Aff214">National Center for Research in Chronic Respiratory Diseases, Tishreen University School of Medicine, Latakia, Syria</nlm:aff></affiliation></author><author><name sortKey="Molimard, M" sort="Molimard, M" uniqKey="Molimard M" first="M." last="Molimard">M. Molimard</name><affiliation><nlm:aff id="Aff215">Département de Pharmacologie, CHU de Bordeaux, Universite Bordeaux, INSERM U657, Bordeaux Cedex, France</nlm:aff></affiliation></author><author><name sortKey="Momas, I" sort="Momas, I" uniqKey="Momas I" first="I." last="Momas">I. Momas</name><affiliation><nlm:aff id="Aff216">Department of Public Health and Biostatistics, EA 4064, Paris Descartes University, Paris, France</nlm:aff></affiliation><affiliation><nlm:aff id="Aff217">Paris Municipal Department of Social Action, Childhood, and Health, Paris, France</nlm:aff></affiliation></author><author><name sortKey="Montilla Santana, A" sort="Montilla Santana, A" uniqKey="Montilla Santana A" first="A." last="Montilla-Santana">A. Montilla-Santana</name><affiliation><nlm:aff id="Aff218">Aura Andalucia, Andalucía, Spain</nlm:aff></affiliation></author><author><name sortKey="Morais Almeida, M" sort="Morais Almeida, M" uniqKey="Morais Almeida M" first="M." last="Morais-Almeida">M. Morais-Almeida</name><affiliation><nlm:aff id="Aff219">Allergy and Clinical Immunology Department, Hospital CUF-Descobertas, Lisbon, Portugal</nlm:aff></affiliation></author><author><name sortKey="Morgan, M" sort="Morgan, M" uniqKey="Morgan M" first="M." last="Morgan">M. Morgan</name><affiliation><nlm:aff id="Aff220">National Clinical Director for Respiratory Services, NHS England, Leeds, England, UK</nlm:aff></affiliation></author><author><name sortKey="Mosges, R" sort="Mosges, R" uniqKey="Mosges R" first="R." last="Mösges">R. Mösges</name><affiliation><nlm:aff id="Aff221">Institute of Medical Statistics, Informatics and Epidemiology, Medical Faculty, University of Cologne, Cologne, Germany</nlm:aff></affiliation></author><author><name sortKey="Mullol, J" sort="Mullol, J" uniqKey="Mullol J" first="J." last="Mullol">J. Mullol</name><affiliation><nlm:aff id="Aff178">Sachs’ Children’s Hospital, Stockholm, Sweden</nlm:aff></affiliation><affiliation><nlm:aff id="Aff179">Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden</nlm:aff></affiliation><affiliation><nlm:aff id="Aff222">Unitat de Rinologia i Clínica de l’Olfacte, Servei d’ORL, Hospital Clínic, Clinical and Experimental Respiratory Immunoallergy, IDIBAPS, Barcelona, Spain</nlm:aff></affiliation></author><author><name sortKey="Nafti, S" sort="Nafti, S" uniqKey="Nafti S" first="S." last="Nafti">S. Nafti</name><affiliation><nlm:aff id="Aff223">Mustapha Hospital, Algers, Algeria</nlm:aff></affiliation></author><author><name sortKey="Namazova Baranova, L" sort="Namazova Baranova, L" uniqKey="Namazova Baranova L" first="L." last="Namazova-Baranova">L. Namazova-Baranova</name><affiliation><nlm:aff id="Aff224">Scientific Centre of Children’s Health Under the Russian Academy of Medical Sciences, Moscow, Russia</nlm:aff></affiliation></author><author><name sortKey="Naclerio, R" sort="Naclerio, R" uniqKey="Naclerio R" first="R." last="Naclerio">R. Naclerio</name><affiliation><nlm:aff id="Aff225">Section of Otolaryngology-Head and Neck Surgery, The University of Chicago Medical Center and The Pritzker School of Medicine, The University of Chicago, Chicago, IL USA</nlm:aff></affiliation></author><author><name sortKey="Neou, A" sort="Neou, A" uniqKey="Neou A" first="A." last="Neou">A. Neou</name><affiliation><nlm:aff id="Aff36">Allergy-Centre-Charité at the Department of Dermatology, Charité - Universitätsmedizin Berlin, Berlin, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="Aff37">Secretary General of the Global Allergy and Asthma European Network (GA²LEN), Berlin, Germany</nlm:aff></affiliation></author><author><name sortKey="Neffen, H" sort="Neffen, H" uniqKey="Neffen H" first="H." last="Neffen">H. Neffen</name><affiliation><nlm:aff id="Aff226">Hospital de Niños Orlando Alassia, Santa Fe, Argentina</nlm:aff></affiliation></author><author><name sortKey="Nekam, K" sort="Nekam, K" uniqKey="Nekam K" first="K." last="Nekam">K. Nekam</name><affiliation><nlm:aff id="Aff227">Hospital of the Hospitaller Brothers in Buda, Budapest, Hungary</nlm:aff></affiliation></author><author><name sortKey="Niggemann, B" sort="Niggemann, B" uniqKey="Niggemann B" first="B." last="Niggemann">B. Niggemann</name><affiliation><nlm:aff id="Aff228">Pediatric Pneumology and Immunology, Charité Universitätsmedizin Berlin, Berlin, Germany</nlm:aff></affiliation></author><author><name sortKey="Ninot, G" sort="Ninot, G" uniqKey="Ninot G" first="G." last="Ninot">G. Ninot</name><affiliation><nlm:aff id="Aff229">EA4556 Epsylon, Université Montpellier 1, Montpellier, France</nlm:aff></affiliation></author><author><name sortKey="Nyembue, T D" sort="Nyembue, T D" uniqKey="Nyembue T" first="T. D." last="Nyembue">T. D. Nyembue</name><affiliation><nlm:aff id="Aff230">ENT Department, University Hospital of Kinshasa, Kinshasa, Congo</nlm:aff></affiliation></author><author><name sortKey="O Ehir, R E" sort="O Ehir, R E" uniqKey="O Ehir R" first="R. E." last="O Ehir">R. E. O Ehir</name><affiliation><nlm:aff id="Aff231">Department of Allergy, Immunology and Respiratory Medicine, Alfred Hospital and Central Clinical School, Monash University, Melbourne, VIC Australia</nlm:aff></affiliation><affiliation><nlm:aff id="Aff232">Department of Immunology, Monash University, Melbourne, VIC Australia</nlm:aff></affiliation></author><author><name sortKey="Ohta, K" sort="Ohta, K" uniqKey="Ohta K" first="K." last="Ohta">K. Ohta</name><affiliation><nlm:aff id="Aff233">National Hospital Organization, Tokyo National Hospital, Tokyo, Japan</nlm:aff></affiliation></author><author><name sortKey="Okamoto, Y" sort="Okamoto, Y" uniqKey="Okamoto Y" first="Y." last="Okamoto">Y. Okamoto</name><affiliation><nlm:aff id="Aff234">Department of Otorhinolaryngology, Chiba University Hospital, Chiba, Japan</nlm:aff></affiliation></author><author><name sortKey="Okubo, K" sort="Okubo, K" uniqKey="Okubo K" first="K." last="Okubo">K. Okubo</name><affiliation><nlm:aff id="Aff235">Department of Otolaryngology, Nippon Medical School, Tokyo, Japan</nlm:aff></affiliation></author><author><name sortKey="Ouedraogo, S" sort="Ouedraogo, S" uniqKey="Ouedraogo S" first="S." last="Ouedraogo">S. Ouedraogo</name><affiliation><nlm:aff id="Aff236">Centre Hospitalier Universitaire Pédiatrique Charles de Gaulle, Ouagadougou, Burkina Faso</nlm:aff></affiliation></author><author><name sortKey="Paggiaro, P" sort="Paggiaro, P" uniqKey="Paggiaro P" first="P." last="Paggiaro">P. Paggiaro</name><affiliation><nlm:aff id="Aff237">Cardio-Thoracic and Vascular Department, University Hospital of Pisa, Pisa, Italy</nlm:aff></affiliation></author><author><name sortKey="Pali Scholl, I" sort="Pali Scholl, I" uniqKey="Pali Scholl I" first="I." last="Pali-Schöll">I. Pali-Schöll</name><affiliation><nlm:aff id="Aff238">Department of Comparative Medicine, Messerli, Research Institute of the University of Veterinary Medicine and Medical University, Vienna, Austria</nlm:aff></affiliation></author><author><name sortKey="Panzner, P" sort="Panzner, P" uniqKey="Panzner P" first="P." last="Panzner">P. Panzner</name><affiliation><nlm:aff id="Aff239">Department of Immunology and Allergology, Faculty of Medicine and Faculty Hospital in Pilsen, Charles University in Prague, Pilsen, Czech Republic</nlm:aff></affiliation></author><author><name sortKey="Papadopoulos, N" sort="Papadopoulos, N" uniqKey="Papadopoulos N" first="N." last="Papadopoulos">N. Papadopoulos</name><affiliation><nlm:aff id="Aff240">Center for Pediatrics and Child Health, Institute of Human Development, Royal Manchester Children’s Hospital, University of Manchester, Manchester, M13 9WL UK</nlm:aff></affiliation><affiliation><nlm:aff id="Aff241">Allergy Department, 2nd Pediatric Clinic, Athens General Children’s Hospital “P&A Kyriakou”, University of Athens, Athens, 11527 Greece</nlm:aff></affiliation></author><author><name sortKey="Papi, A" sort="Papi, A" uniqKey="Papi A" first="A." last="Papi">A. Papi</name><affiliation><nlm:aff id="Aff242">Respiratory Medicine, Department of Medical Sciences, University of Ferrara, Ferrara, Italy</nlm:aff></affiliation></author><author><name sortKey="Park, H S" sort="Park, H S" uniqKey="Park H" first="H. S." last="Park">H. S. Park</name><affiliation><nlm:aff id="Aff243">Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, South Korea</nlm:aff></affiliation></author><author><name sortKey="Passalacqua, G" sort="Passalacqua, G" uniqKey="Passalacqua G" first="G." last="Passalacqua">G. Passalacqua</name><affiliation><nlm:aff id="Aff52">Allergy and Respiratory Diseases Clinic, DIMI, IRCCS AOU San Martino-IST, University of Genoa, Genoa, Italy</nlm:aff></affiliation></author><author><name sortKey="Pavord, I" sort="Pavord, I" uniqKey="Pavord I" first="I." last="Pavord">I. Pavord</name><affiliation><nlm:aff id="Aff244">Nuffield Department of Medicine, University of Oxford, Oxford, UK</nlm:aff></affiliation></author><author><name sortKey="Pawankar, R" sort="Pawankar, R" uniqKey="Pawankar R" first="R." last="Pawankar">R. Pawankar</name><affiliation><nlm:aff id="Aff245">Department of Pediatrics, Nippon Medical School, Tokyo, Japan</nlm:aff></affiliation></author><author><name sortKey="Pengelly, R" sort="Pengelly, R" uniqKey="Pengelly R" first="R." last="Pengelly">R. Pengelly</name><affiliation><nlm:aff id="Aff246">Department of Health, Social Services and Public Safety, Belfast, Northern Ireland, UK</nlm:aff></affiliation></author><author><name sortKey="Pfaar, O" sort="Pfaar, O" uniqKey="Pfaar O" first="O." last="Pfaar">O. Pfaar</name><affiliation><nlm:aff id="Aff247">Center for Rhinology and Allergology, Wiesbaden, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="Aff248">Department of Otorhinolaryngology, Head and Neck Surgery, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany</nlm:aff></affiliation></author><author><name sortKey="Picard, R" sort="Picard, R" uniqKey="Picard R" first="R." last="Picard">R. Picard</name><affiliation><nlm:aff id="Aff249">Conseil Général de l’Economie. Ministère de l’Economie, de l’Industrie et du Numérique, Paris, France</nlm:aff></affiliation></author><author><name sortKey="Pigearias, B" sort="Pigearias, B" uniqKey="Pigearias B" first="B." last="Pigearias">B. Pigearias</name><affiliation><nlm:aff id="Aff174">Société de Pneumologie de Langue Française, Espace francophone de Pneumologie, Paris, France</nlm:aff></affiliation></author><author><name sortKey="Pin, I" sort="Pin, I" uniqKey="Pin I" first="I." last="Pin">I. Pin</name><affiliation><nlm:aff id="Aff250">Département de pédiatrie, CHU de Grenoble, BP 217, 38043 Grenoble Cedex 9, France</nlm:aff></affiliation></author><author><name sortKey="Plavec, D" sort="Plavec, D" uniqKey="Plavec D" first="D." last="Plavec">D. Plavec</name><affiliation><nlm:aff id="Aff251">Children’s Hospital Srebrnjak, Zagreb, School of Medicine, University J.J. Strossmayer, Osijek, Croatia</nlm:aff></affiliation></author><author><name sortKey="Poethig, D" sort="Poethig, D" uniqKey="Poethig D" first="D." last="Poethig">D. Poethig</name><affiliation><nlm:aff id="Aff252">Im GerontoLab Europe - Europäische Vereinigung für Vitalität und Aktives Altern (eVAA) e.V., Leipzig, Germany</nlm:aff></affiliation></author><author><name sortKey="Pohl, W" sort="Pohl, W" uniqKey="Pohl W" first="W." last="Pohl">W. Pohl</name><affiliation><nlm:aff id="Aff253">Karl Landsteiner Institute for Clinical and Experimental Pneumology, Hietzing Hospital, Wolkersbergenstraße 1, 1130 Vienna, Austria</nlm:aff></affiliation></author><author><name sortKey="Popov, T A" sort="Popov, T A" uniqKey="Popov T" first="T. A." last="Popov">T. A. Popov</name><affiliation><nlm:aff id="Aff254">Clinic of Allergy and Asthma, Medical University Sofia, 1Sv. Georgi Sofiyski St., 1431 Sofia, Bulgaria</nlm:aff></affiliation></author><author><name sortKey="Portejoie, F" sort="Portejoie, F" uniqKey="Portejoie F" first="F." last="Portejoie">F. Portejoie</name><affiliation><nlm:aff id="Aff2">MACVIA-LR, Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc Roussilon, European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier, France</nlm:aff></affiliation></author><author><name sortKey="Potter, P" sort="Potter, P" uniqKey="Potter P" first="P." last="Potter">P. Potter</name><affiliation><nlm:aff id="Aff255">Allergy Diagnostic and Clinical Research Unit, University of Cape Town Lung Institute, Cape Town, South Africa</nlm:aff></affiliation></author><author><name sortKey="Postma, D" sort="Postma, D" uniqKey="Postma D" first="D." last="Postma">D. Postma</name><affiliation><nlm:aff id="Aff256">Department of Pulmonary Medicine and Tuberculosis, GRIAC Research Institute, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Price, D" sort="Price, D" uniqKey="Price D" first="D." last="Price">D. Price</name><affiliation><nlm:aff id="Aff257">Academic Centre of Primary Care, University of Aberdeen, Aberdeen, UK</nlm:aff></affiliation><affiliation><nlm:aff id="Aff258">Research in Real-Life, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Rabe, K F" sort="Rabe, K F" uniqKey="Rabe K" first="K. F." last="Rabe">K. F. Rabe</name><affiliation><nlm:aff id="Aff259">LungenClinic Grosshansdorf, Airway Research Center North, Member of the German Center for Lung Research (DZL), Grosshansdorf, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="Aff260">Department of Medicine, Christian Albrechts University, Airway Research Center North, Member of the German Center for Lung Research (DZL), Kiel, Germany</nlm:aff></affiliation></author><author><name sortKey="Raciborski, F" sort="Raciborski, F" uniqKey="Raciborski F" first="F." last="Raciborski">F. Raciborski</name><affiliation><nlm:aff id="Aff28">Department of Prevention of Environmental Hazards and Allergology, Medical University of Warsaw, Warsaw, Poland</nlm:aff></affiliation></author><author><name sortKey="Radier Pontal, F" sort="Radier Pontal, F" uniqKey="Radier Pontal F" first="F." last="Radier Pontal">F. Radier Pontal</name><affiliation><nlm:aff id="Aff261">Conseil Départemental de l’Ordre des Pharmaciens, Maison des Professions Libérales, 34000 Montpellier, France</nlm:aff></affiliation></author><author><name sortKey="Repka Ramirez, S" sort="Repka Ramirez, S" uniqKey="Repka Ramirez S" first="S." last="Repka-Ramirez">S. Repka-Ramirez</name><affiliation><nlm:aff id="Aff262">SLAAI, Barranquilla, Colombia</nlm:aff></affiliation></author><author><name sortKey="Reitamo, S" sort="Reitamo, S" uniqKey="Reitamo S" first="S." last="Reitamo">S. Reitamo</name><affiliation><nlm:aff id="Aff19">Skin and Allergy Hospital, Helsinki University Hospital, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Rennard, S" sort="Rennard, S" uniqKey="Rennard S" first="S." last="Rennard">S. Rennard</name><affiliation><nlm:aff id="Aff263">Division of Pulmonary, Critical Care, Sleep and Allergy, University of Nebraska Medical Center, Omaha, NE USA</nlm:aff></affiliation></author><author><name sortKey="Rodenas, F" sort="Rodenas, F" uniqKey="Rodenas F" first="F." last="Rodenas">F. Rodenas</name><affiliation><nlm:aff id="Aff135">Polibienestar Research Institute, University of Valencia, Valencia, Spain</nlm:aff></affiliation></author><author><name sortKey="Roberts, J" sort="Roberts, J" uniqKey="Roberts J" first="J." last="Roberts">J. Roberts</name><affiliation><nlm:aff id="Aff264">Salford, Royal NHS Foundation Trust and NHS England North, London, UK</nlm:aff></affiliation></author><author><name sortKey="Roca, J" sort="Roca, J" uniqKey="Roca J" first="J." last="Roca">J. Roca</name><affiliation><nlm:aff id="Aff40">Thorax Institute, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain</nlm:aff></affiliation></author><author><name sortKey="Rodriguez Ma As, L" sort="Rodriguez Ma As, L" uniqKey="Rodriguez Ma As L" first="L." last="Rodriguez Ma As">L. Rodriguez Ma As</name><affiliation><nlm:aff id="Aff265">Hospital Universitario de Getafe-Servicio Madrileño de Salud, Madrid, Spain</nlm:aff></affiliation></author><author><name sortKey="Rolland, C" sort="Rolland, C" uniqKey="Rolland C" first="C." last="Rolland">C. Rolland</name><affiliation><nlm:aff id="Aff266">Association Asthme et Allergie, Paris, France</nlm:aff></affiliation></author><author><name sortKey="Roman Rodriguez, M" sort="Roman Rodriguez, M" uniqKey="Roman Rodriguez M" first="M." last="Roman Rodriguez">M. Roman Rodriguez</name><affiliation><nlm:aff id="Aff267">Primary Care Respiratory Research Unit, Institutode Investigación Sanitaria de Palma IdisPa, Palma De Mallorca, Spain</nlm:aff></affiliation></author><author><name sortKey="Romano, A" sort="Romano, A" uniqKey="Romano A" first="A." last="Romano">A. Romano</name><affiliation><nlm:aff id="Aff268">Allergy Unit, Complesso integrato Columbus, Rome, Italy</nlm:aff></affiliation></author><author><name sortKey="Rosado Pinto, J" sort="Rosado Pinto, J" uniqKey="Rosado Pinto J" first="J." last="Rosado-Pinto">J. Rosado-Pinto</name><affiliation><nlm:aff id="Aff269">Serviço de Imunoalergologia, Hospital da Luz, Lisbon, Portugal</nlm:aff></affiliation></author><author><name sortKey="Rosario, N" sort="Rosario, N" uniqKey="Rosario N" first="N." last="Rosario">N. Rosario</name><affiliation><nlm:aff id="Aff270">Hospital de Clinicas, University of Parana, Curitiba, PR Brazil</nlm:aff></affiliation></author><author><name sortKey="Rosenwasser, L" sort="Rosenwasser, L" uniqKey="Rosenwasser L" first="L." last="Rosenwasser">L. Rosenwasser</name><affiliation><nlm:aff id="Aff271">Department of Allergy, Asthma, and Immunology, Children’s Mercy Hospitals and Clinics and Pediatrics, Medicine University of Misouri-Kansas City School of Medicine, Kansas City, MO USA</nlm:aff></affiliation></author><author><name sortKey="Rottem, M" sort="Rottem, M" uniqKey="Rottem M" first="M." last="Rottem">M. Rottem</name><affiliation><nlm:aff id="Aff272">Division of Allergy Asthma and Clinical Immunology, Emek Medical Center, Afula, Israel</nlm:aff></affiliation></author><author><name sortKey="Ryan, D" sort="Ryan, D" uniqKey="Ryan D" first="D." last="Ryan">D. Ryan</name><affiliation><nlm:aff id="Aff273">Woodbrook Medical Centre, Loughborough, UK</nlm:aff></affiliation><affiliation><nlm:aff id="Aff274">Honorary Clinical Research Fellow, Allergy and Respiratory Research Group, The University of Edinburgh, Edinburgh, UK</nlm:aff></affiliation></author><author><name sortKey="Sanchez Borges, M" sort="Sanchez Borges, M" uniqKey="Sanchez Borges M" first="M." last="Sanchez-Borges">M. Sanchez-Borges</name><affiliation><nlm:aff id="Aff275">Allergy and Clinical Immunology Department, Centro Médico-Docente la, Trinidad and Clínica El Avila, 6a transversal Urb, Altamira, piso 8, consultorio 803, Caracas, 1060 Venezuela</nlm:aff></affiliation></author><author><name sortKey="Scadding, G K" sort="Scadding, G K" uniqKey="Scadding G" first="G. K." last="Scadding">G. K. Scadding</name><affiliation><nlm:aff id="Aff276">The Royal National TNE Hospital, University College London, London, UK</nlm:aff></affiliation></author><author><name sortKey="Schunemann, H J" sort="Schunemann, H J" uniqKey="Schunemann H" first="H. J." last="Schunemann">H. J. Schunemann</name><affiliation><nlm:aff id="Aff76">Department of Clinical Epidemiology and Biostatistics, McMaster University, HSC Room 2C16, 1280 Main Street West Hamilton, Hamilton, Canada</nlm:aff></affiliation></author><author><name sortKey="Serrano, E" sort="Serrano, E" uniqKey="Serrano E" first="E." last="Serrano">E. Serrano</name><affiliation><nlm:aff id="Aff277">Otolaryngology and Head and Neck Surgery, CHU Rangueil-Larrey, Toulouse, France</nlm:aff></affiliation></author><author><name sortKey="Schmid Grendelmeier, P" sort="Schmid Grendelmeier, P" uniqKey="Schmid Grendelmeier P" first="P." last="Schmid-Grendelmeier">P. Schmid-Grendelmeier</name><affiliation><nlm:aff id="Aff278">Allergy Unit, Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland</nlm:aff></affiliation></author><author><name sortKey="Schulz, H" sort="Schulz, H" uniqKey="Schulz H" first="H." last="Schulz">H. Schulz</name><affiliation><nlm:aff id="Aff279">Helmholtz Zentrum München/Institute of Epidemiology I, Neuherberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Sheikh, A" sort="Sheikh, A" uniqKey="Sheikh A" first="A." last="Sheikh">A. Sheikh</name><affiliation><nlm:aff id="Aff280">Allergy and Respiratory Research Group, Centre for Population Health Sciences, Medical School, The University of Edinburgh, Edinburgh, UK</nlm:aff></affiliation></author><author><name sortKey="Shields, M" sort="Shields, M" uniqKey="Shields M" first="M." last="Shields">M. Shields</name><affiliation><nlm:aff id="Aff281">Child Health, Queen’s University Belfast and Royal Belfast Hospital for Sick Children, Belfast, UK</nlm:aff></affiliation></author><author><name sortKey="Siafakas, N" sort="Siafakas, N" uniqKey="Siafakas N" first="N." last="Siafakas">N. Siafakas</name><affiliation><nlm:aff id="Aff282">Department of Thoracic Medicine, University Hospital of Heraklion, Crete, Greece</nlm:aff></affiliation></author><author><name sortKey="Sibille, Y" sort="Sibille, Y" uniqKey="Sibille Y" first="Y." last="Sibille">Y. Sibille</name><affiliation><nlm:aff id="Aff283">University Hospital of Mont-Godinne, Catholic University of Louvain, Yvoir, Belgium</nlm:aff></affiliation></author><author><name sortKey="Similowski, T" sort="Similowski, T" uniqKey="Similowski T" first="T." last="Similowski">T. Similowski</name><affiliation><nlm:aff id="Aff284">Sorbonne Universités, UPMC Univ Paris 06, UMR_S 1158 Neurophysiologie Respiratoire Expérimentale et Clinique, Paris, France</nlm:aff></affiliation><affiliation><nlm:aff id="Aff285">INSERM, UMR_S 1158 Neurophysiologie Respiratoire Expérimentale et Clinique, Paris, France</nlm:aff></affiliation><affiliation><nlm:aff id="Aff286">Department R3S, AP-HP, Groupe, Paris, France</nlm:aff></affiliation></author><author><name sortKey="Simons, F E R" sort="Simons, F E R" uniqKey="Simons F" first="F. E. R." last="Simons">F. E. R. Simons</name><affiliation><nlm:aff id="Aff287">Department of Pediatrics and Child Health, Department of Immunology, Faculty of Medicine, University of Manitoba, Winnipeg, MB Canada</nlm:aff></affiliation></author><author><name sortKey="Sisul, J C" sort="Sisul, J C" uniqKey="Sisul J" first="J. C." last="Sisul">J. C. Sisul</name><affiliation><nlm:aff id="Aff288">Sociedad Paraguaya de Alergia Asma e Inmunología, Asunción, Paraguay</nlm:aff></affiliation></author><author><name sortKey="Skrindo, I" sort="Skrindo, I" uniqKey="Skrindo I" first="I." last="Skrindo">I. Skrindo</name><affiliation><nlm:aff id="Aff189">Department of Paediatrics, Oslo University Hospital, Oslo, Norway</nlm:aff></affiliation><affiliation><nlm:aff id="Aff190">Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway</nlm:aff></affiliation></author><author><name sortKey="Smit, H A" sort="Smit, H A" uniqKey="Smit H" first="H. A." last="Smit">H. A. Smit</name><affiliation><nlm:aff id="Aff289">Julius Center of Health Sciences and Primary Care, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Sole, D" sort="Sole, D" uniqKey="Sole D" first="D." last="Solé">D. Solé</name><affiliation><nlm:aff id="Aff290">Division of Allergy, Clinical Immunology and Rheumatology, Department of Pediatrics, Federal University of São Paulo, São Paulo, Brazil</nlm:aff></affiliation></author><author><name sortKey="Sooronbaev, T" sort="Sooronbaev, T" uniqKey="Sooronbaev T" first="T." last="Sooronbaev">T. Sooronbaev</name><affiliation><nlm:aff id="Aff291">Kyrgyzstan National Centre of Cardiology and Internal Medicine, Euro-Asian Respiratory Society, Bishkek, Kyrgyzstan</nlm:aff></affiliation></author><author><name sortKey="Spranger, O" sort="Spranger, O" uniqKey="Spranger O" first="O." last="Spranger">O. Spranger</name><affiliation><nlm:aff id="Aff127">Global Allergy and Asthma Platform (GAAPP), Altgasse 8-10, 1130 Vienna, Austria</nlm:aff></affiliation></author><author><name sortKey="Stelmach, R" sort="Stelmach, R" uniqKey="Stelmach R" first="R." last="Stelmach">R. Stelmach</name><affiliation><nlm:aff id="Aff292">Pulmonary Division, Heart Institute (InCor), Hospital da Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Brazil</nlm:aff></affiliation></author><author><name sortKey="Sterk, P J" sort="Sterk, P J" uniqKey="Sterk P" first="P. J." last="Sterk">P. J. Sterk</name><affiliation><nlm:aff id="Aff293">Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Sunyer, J" sort="Sunyer, J" uniqKey="Sunyer J" first="J." last="Sunyer">J. Sunyer</name><affiliation><nlm:aff id="Aff45">Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain</nlm:aff></affiliation><affiliation><nlm:aff id="Aff46">Hospital del Mar Research Institute (IMIM), Barcelona, Spain</nlm:aff></affiliation><affiliation><nlm:aff id="Aff47">CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain</nlm:aff></affiliation><affiliation><nlm:aff id="Aff48">Department of Experimental and Health Sciences, University of Pompeu Fabra (UPF), Barcelona, Spain</nlm:aff></affiliation></author><author><name sortKey="Thijs, C" sort="Thijs, C" uniqKey="Thijs C" first="C." last="Thijs">C. Thijs</name><affiliation><nlm:aff id="Aff294">Department of Epidemiology, CAPHRI School of Public Health and Primary Care, Maastricht University, Maastricht, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="To, T" sort="To, T" uniqKey="To T" first="T." last="To">T. To</name><affiliation><nlm:aff id="Aff295">Sidkkids hospitala and Institute of Health Policy, Management and Evaluation, Toronto, ON Canada</nlm:aff></affiliation></author><author><name sortKey="Todo Bom, A" sort="Todo Bom, A" uniqKey="Todo Bom A" first="A." last="Todo-Bom">A. Todo-Bom</name><affiliation><nlm:aff id="Aff296">Centre of Pneumology, Faculty of Medicine, University of Coimbra, Coimbra, Portugal</nlm:aff></affiliation></author><author><name sortKey="Triggiani, M" sort="Triggiani, M" uniqKey="Triggiani M" first="M." last="Triggiani">M. Triggiani</name><affiliation><nlm:aff id="Aff297">Division of Allergy and Clinical Immunology, University of Salerno, Salerno, Italy</nlm:aff></affiliation></author><author><name sortKey="Valenta, R" sort="Valenta, R" uniqKey="Valenta R" first="R." last="Valenta">R. Valenta</name><affiliation><nlm:aff id="Aff298">Division of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria</nlm:aff></affiliation></author><author><name sortKey="Valero, A L" sort="Valero, A L" uniqKey="Valero A" first="A. L." last="Valero">A. L. Valero</name><affiliation><nlm:aff id="Aff299">Pneumology and Allergy Department, Hospital Clínic, Clinical and Experimental Respiratory Immunoallergy, IDIBAPS, Barcelona, Spain</nlm:aff></affiliation></author><author><name sortKey="Valia, E" sort="Valia, E" uniqKey="Valia E" first="E." last="Valia">E. Valia</name><affiliation><nlm:aff id="Aff135">Polibienestar Research Institute, University of Valencia, Valencia, Spain</nlm:aff></affiliation></author><author><name sortKey="Valovirta, E" sort="Valovirta, E" uniqKey="Valovirta E" first="E." last="Valovirta">E. Valovirta</name><affiliation><nlm:aff id="Aff300">Department of Lung Diseases and Clinical Allergology, University of Turku, Turku, Finland</nlm:aff></affiliation></author><author><name sortKey="Van Ganse, E" sort="Van Ganse, E" uniqKey="Van Ganse E" first="E." last="Van Ganse">E. Van Ganse</name><affiliation><nlm:aff id="Aff301">Unité de Pharmacoépidémiologie, CHU-Lyon - UR 5558 CNRS, Université Claude Bernard, Lyon, Villeurbanne, France</nlm:aff></affiliation></author><author><name sortKey="Van Hage, M" sort="Van Hage, M" uniqKey="Van Hage M" first="M." last="Van Hage">M. Van Hage</name><affiliation><nlm:aff id="Aff302">Clinical Immunology and Allergy Unit, Department of Medicine Solna, Karolinska Institutet and University Hospital, Stockholm, Sweden</nlm:aff></affiliation></author><author><name sortKey="Vandenplas, O" sort="Vandenplas, O" uniqKey="Vandenplas O" first="O." last="Vandenplas">O. Vandenplas</name><affiliation><nlm:aff id="Aff303">Department of Chest Medicine, Centre Hospitalier Universitaire Dinant-Godinne, Université Catholique de Louvain, Yvoir, Belgium</nlm:aff></affiliation></author><author><name sortKey="Vasankari, T" sort="Vasankari, T" uniqKey="Vasankari T" first="T." last="Vasankari">T. Vasankari</name><affiliation><nlm:aff id="Aff304">FILHA, Finnish Lung Association, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Vellas, B" sort="Vellas, B" uniqKey="Vellas B" first="B." last="Vellas">B. Vellas</name><affiliation><nlm:aff id="Aff305">Gérontopôle, CHU Toulouse, Toulouse, France</nlm:aff></affiliation></author><author><name sortKey="Vestbo, J" sort="Vestbo, J" uniqKey="Vestbo J" first="J." last="Vestbo">J. Vestbo</name><affiliation><nlm:aff id="Aff306">Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK</nlm:aff></affiliation><affiliation><nlm:aff id="Aff307">University Hospital of South Manchester, Manchester NHS Foundation Trust, Manchester, UK</nlm:aff></affiliation></author><author><name sortKey="Vezzani, G" sort="Vezzani, G" uniqKey="Vezzani G" first="G." last="Vezzani">G. Vezzani</name><affiliation><nlm:aff id="Aff308">Pulmonary Unit, Department of Cardiology, Thoracic and Vascular Medicine, Arcispedale S.Maria Nuova/IRCCS, Research Hospital, Reggio Emilia, Italy</nlm:aff></affiliation><affiliation><nlm:aff id="Aff309">Regional Agency for Health and Social Care, Reggio Emilia, Italy</nlm:aff></affiliation></author><author><name sortKey="Vichyanond, P" sort="Vichyanond, P" uniqKey="Vichyanond P" first="P." last="Vichyanond">P. Vichyanond</name><affiliation><nlm:aff id="Aff310">Division of Allergy and Immunology, Department of Pediatrics, Siriraj Hospital, Mahidol University Faculty of Medicine, Bangkok, 10700 Thailand</nlm:aff></affiliation></author><author><name sortKey="Viegi, G" sort="Viegi, G" uniqKey="Viegi G" first="G." last="Viegi">G. Viegi</name><affiliation><nlm:aff id="Aff311">Pulmonary Environmental Epidemiology Unit, CNR Institute of Clinical Physiology, Pisa, Via Trieste 41, 56126 Pisa, Italy</nlm:aff></affiliation><affiliation><nlm:aff id="Aff312">CNR Institute of Biomedicine and Molecular Immunology “A. Monroy”, Via U. La Malfa 153, 90146 Palermo, Italy</nlm:aff></affiliation></author><author><name sortKey="Vogelmeier, C" sort="Vogelmeier, C" uniqKey="Vogelmeier C" first="C." last="Vogelmeier">C. Vogelmeier</name><affiliation><nlm:aff id="Aff313">Department of Medicine, Pulmonary and Critical Care Medicine, University Medical Center Giessen and Marburg, Philipps-University Marburg, Marburg, Germany</nlm:aff></affiliation></author><author><name sortKey="Vontetsianos, T" sort="Vontetsianos, T" uniqKey="Vontetsianos T" first="T." last="Vontetsianos">T. Vontetsianos</name><affiliation><nlm:aff id="Aff314">Sotiria Hospital, Athens, Greece</nlm:aff></affiliation></author><author><name sortKey="Wagenmann, M" sort="Wagenmann, M" uniqKey="Wagenmann M" first="M." last="Wagenmann">M. Wagenmann</name><affiliation><nlm:aff id="Aff315">Department of Otorhinolaryngology, HNO-Klinik, Universitätsklinikum Düsseldorf, Düsseldorf, Germany</nlm:aff></affiliation></author><author><name sortKey="Wallaert, B" sort="Wallaert, B" uniqKey="Wallaert B" first="B." last="Wallaert">B. Wallaert</name><affiliation><nlm:aff id="Aff316">Hôpital Albert Calmette, CHRU, Lille, France</nlm:aff></affiliation></author><author><name sortKey="Walker, S" sort="Walker, S" uniqKey="Walker S" first="S." last="Walker">S. Walker</name><affiliation><nlm:aff id="Aff317">Asthma UK, Mansell Street, London, UK</nlm:aff></affiliation></author><author><name sortKey="Wang, D Y" sort="Wang, D Y" uniqKey="Wang D" first="D. Y." last="Wang">D. Y. Wang</name><affiliation><nlm:aff id="Aff318">Department of Otolaryngology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore</nlm:aff></affiliation></author><author><name sortKey="Wahn, U" sort="Wahn, U" uniqKey="Wahn U" first="U." last="Wahn">U. Wahn</name><affiliation><nlm:aff id="Aff228">Pediatric Pneumology and Immunology, Charité Universitätsmedizin Berlin, Berlin, Germany</nlm:aff></affiliation></author><author><name sortKey="Wickman, M" sort="Wickman, M" uniqKey="Wickman M" first="M." last="Wickman">M. Wickman</name><affiliation><nlm:aff id="Aff205">Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden</nlm:aff></affiliation></author><author><name sortKey="Williams, D M" sort="Williams, D M" uniqKey="Williams D" first="D. M." last="Williams">D. M. Williams</name><affiliation><nlm:aff id="Aff319">Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC USA</nlm:aff></affiliation></author><author><name sortKey="Williams, S" sort="Williams, S" uniqKey="Williams S" first="S." last="Williams">S. Williams</name><affiliation><nlm:aff id="Aff14">International Primary Care Respiratory Group, Westhill, UK</nlm:aff></affiliation></author><author><name sortKey="Wright, J" sort="Wright, J" uniqKey="Wright J" first="J." last="Wright">J. Wright</name><affiliation><nlm:aff id="Aff320">Bradford Institute for Health Research, Bradford Royal Infirmary, Bradford, UK</nlm:aff></affiliation></author><author><name sortKey="Yawn, B P" sort="Yawn, B P" uniqKey="Yawn B" first="B. P." last="Yawn">B. P. Yawn</name><affiliation><nlm:aff id="Aff321">Department of Research, Olmsted Medical Center, Rochester, MN USA</nlm:aff></affiliation></author><author><name sortKey="Yiallouros, P K" sort="Yiallouros, P K" uniqKey="Yiallouros P" first="P. K." last="Yiallouros">P. K. Yiallouros</name><affiliation><nlm:aff id="Aff322">Cyprus International Institute for Environmental and Public Health in Association with Harvard School of Public Health, Cyprus University of Technology, Limassol, Cyprus</nlm:aff></affiliation><affiliation><nlm:aff id="Aff323">Department of Pediatrics, Hospital “Archbishop Makarios III”, Nicosia, Cyprus</nlm:aff></affiliation></author><author><name sortKey="Yusuf, O M" sort="Yusuf, O M" uniqKey="Yusuf O" first="O. M." last="Yusuf">O. M. Yusuf</name><affiliation><nlm:aff id="Aff324">The Allergy and Asthma Institute, Lahore, Pakistan</nlm:aff></affiliation></author><author><name sortKey="Zaidi, A" sort="Zaidi, A" uniqKey="Zaidi A" first="A." last="Zaidi">A. Zaidi</name><affiliation><nlm:aff id="Aff325">Social Sciences, University of Southampton, Southampton, UK</nlm:aff></affiliation></author><author><name sortKey="Zar, H J" sort="Zar, H J" uniqKey="Zar H" first="H. J." last="Zar">H. J. Zar</name><affiliation><nlm:aff id="Aff326">Department of Paediatrics and Child Health, Red Cross Children’s Hospital, and MRC Unit on Child and Adolescent Health, University of Cape Town, Cape Town, South Africa</nlm:aff></affiliation></author><author><name sortKey="Zernotti, M E" sort="Zernotti, M E" uniqKey="Zernotti M" first="M. E." last="Zernotti">M. E. Zernotti</name><affiliation><nlm:aff id="Aff327">Universidad Católica de Córdoba, Córdoba, Argentina</nlm:aff></affiliation></author><author><name sortKey="Zhang, L" sort="Zhang, L" uniqKey="Zhang L" first="L." last="Zhang">L. Zhang</name><affiliation><nlm:aff id="Aff328">Department of Otolaryngology, Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730 China</nlm:aff></affiliation></author><author><name sortKey="Zhong, N" sort="Zhong, N" uniqKey="Zhong N" first="N." last="Zhong">N. Zhong</name><affiliation><nlm:aff id="Aff188">State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120 China</nlm:aff></affiliation></author><author><name sortKey="Zidarn, M" sort="Zidarn, M" uniqKey="Zidarn M" first="M." last="Zidarn">M. Zidarn</name><affiliation><nlm:aff id="Aff329">University Clinic of Respiratory and Allergic Diseases, Golnik, Slovenia</nlm:aff></affiliation></author><author><name sortKey="Mercier, J" sort="Mercier, J" uniqKey="Mercier J" first="J." last="Mercier">J. Mercier</name><affiliation><nlm:aff id="Aff330">Department of Physiology, CHRU and Vice President for Research, University Montpellier, Montpellier, France</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27478588</idno><idno type="pmc">4966705</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966705</idno><idno type="RBID">PMC:4966705</idno><idno type="doi">10.1186/s13601-016-0116-9</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">000E77</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000E77</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5)</title><author><name sortKey="Bousquet, J" sort="Bousquet, J" uniqKey="Bousquet J" first="J." last="Bousquet">J. Bousquet</name><affiliation><nlm:aff id="Aff1">CHRU, University Hospital, 371 Avenue du Doyen Gaston Giraud, 34295 Montpellier Cedex 5, France</nlm:aff></affiliation><affiliation><nlm:aff id="Aff2">MACVIA-LR, Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc Roussilon, European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier, France</nlm:aff></affiliation><affiliation><nlm:aff id="Aff3">INSERM, VIMA: Ageing and Chronic Diseases, Epidemiological and Public Health Approaches, U1168, Paris, France</nlm:aff></affiliation><affiliation><nlm:aff id="Aff4">UVSQ, UMR-S 1168, Université Versailles St-Quentin-en-Yvelines, Paris, France</nlm:aff></affiliation></author><author><name sortKey="Farrell, J" sort="Farrell, J" uniqKey="Farrell J" first="J." last="Farrell">J. Farrell</name><affiliation><nlm:aff id="Aff5">Department of Health, Social Services and Public Safety, Belfast, Northern Ireland, UK</nlm:aff></affiliation></author><author><name sortKey="Crooks, G" sort="Crooks, G" uniqKey="Crooks G" first="G." last="Crooks">G. Crooks</name><affiliation><nlm:aff id="Aff6">EIP on AHA, European Innovation Partnership on Active and Healthy Ageing, Reference Site, Scottish Centre for Telehealth and Telecare, NHS 24, Glasgow, UK</nlm:aff></affiliation></author><author><name sortKey="Hellings, P" sort="Hellings, P" uniqKey="Hellings P" first="P." last="Hellings">P. Hellings</name><affiliation><nlm:aff id="Aff7">Laboratory of Clinical Immunology, Department of Microbiology and Immunology, KU Leuven, Louvain, Belgium</nlm:aff></affiliation><affiliation><nlm:aff id="Aff8">European Academy of Allergy and Clinical Immunology, Zurich, Switzerland</nlm:aff></affiliation></author><author><name sortKey="Bel, E H" sort="Bel, E H" uniqKey="Bel E" first="E. H." last="Bel">E. H. Bel</name><affiliation><nlm:aff id="Aff9">Department of Respiratory Medicine, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, The Netherlands</nlm:aff></affiliation><affiliation><nlm:aff id="Aff10">European Respiratory Society, Lausanne, Switzerland</nlm:aff></affiliation></author><author><name sortKey="Bewick, M" sort="Bewick, M" uniqKey="Bewick M" first="M." last="Bewick">M. Bewick</name><affiliation><nlm:aff id="Aff11">iQ4U Consultants Ltd, London, UK</nlm:aff></affiliation></author><author><name sortKey="Chavannes, N H" sort="Chavannes, N H" uniqKey="Chavannes N" first="N. H." last="Chavannes">N. H. Chavannes</name><affiliation><nlm:aff id="Aff12">Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands</nlm:aff></affiliation><affiliation><nlm:aff id="Aff13">Global Alliance Against Chronic Respiratory Diseases (GARD), Cape Town, South Africa</nlm:aff></affiliation><affiliation><nlm:aff id="Aff14">International Primary Care Respiratory Group, Westhill, UK</nlm:aff></affiliation></author><author><name sortKey="De Sousa, J Correia" sort="De Sousa, J Correia" uniqKey="De Sousa J" first="J. Correia" last="De Sousa">J. Correia De Sousa</name><affiliation><nlm:aff id="Aff15">Life and Health Sciences Research Institute, ICVS, School of Health Sciences, University of Minho, Braga, Portugal</nlm:aff></affiliation></author><author><name sortKey="Cruz, A A" sort="Cruz, A A" uniqKey="Cruz A" first="A. A." last="Cruz">A. A. Cruz</name><affiliation><nlm:aff id="Aff13">Global Alliance Against Chronic Respiratory Diseases (GARD), Cape Town, South Africa</nlm:aff></affiliation><affiliation><nlm:aff id="Aff16">ProAR – Nucleo de Excelencia em Asma, Federal University of Bahia, Bahia, Brazil</nlm:aff></affiliation><affiliation><nlm:aff id="Aff17">GARD Executive Committee, Bahia, Brazil</nlm:aff></affiliation></author><author><name sortKey="Haahtela, T" sort="Haahtela, T" uniqKey="Haahtela T" first="T." last="Haahtela">T. Haahtela</name><affiliation><nlm:aff id="Aff18">EIP on AHA Commitment for Action, Lisbon, Portugal</nlm:aff></affiliation><affiliation><nlm:aff id="Aff19">Skin and Allergy Hospital, Helsinki University Hospital, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Joos, G" sort="Joos, G" uniqKey="Joos G" first="G." last="Joos">G. Joos</name><affiliation><nlm:aff id="Aff20">Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium</nlm:aff></affiliation></author><author><name sortKey="Khaltaev, N" sort="Khaltaev, N" uniqKey="Khaltaev N" first="N." last="Khaltaev">N. Khaltaev</name><affiliation><nlm:aff id="Aff13">Global Alliance Against Chronic Respiratory Diseases (GARD), Cape Town, South Africa</nlm:aff></affiliation></author><author><name sortKey="Malva, J" sort="Malva, J" uniqKey="Malva J" first="J." last="Malva">J. Malva</name><affiliation><nlm:aff id="Aff21">Faculty of Medicine, University of Coimbra, Coimbra, Portugal</nlm:aff></affiliation><affiliation><nlm:aff id="Aff22">Ageing@Coimbra Reference Site, Coimbra, Portugal</nlm:aff></affiliation></author><author><name sortKey="Muraro, A" sort="Muraro, A" uniqKey="Muraro A" first="A." last="Muraro">A. Muraro</name><affiliation><nlm:aff id="Aff8">European Academy of Allergy and Clinical Immunology, Zurich, Switzerland</nlm:aff></affiliation><affiliation><nlm:aff id="Aff23">Food Allergy Referral Centre Veneto Region, Department of Women and Child Health, Padua General University Hospital, Padua, Italy</nlm:aff></affiliation></author><author><name sortKey="Nogues, M" sort="Nogues, M" uniqKey="Nogues M" first="M." last="Nogues">M. Nogues</name><affiliation><nlm:aff id="Aff24">Caisse Assurance Retraite et Santé Au Travail Languedoc-Roussillon (CARSAT-LR), 34000 Montpellier, France</nlm:aff></affiliation></author><author><name sortKey="Palkonen, S" sort="Palkonen, S" uniqKey="Palkonen S" first="S." last="Palkonen">S. Palkonen</name><affiliation><nlm:aff id="Aff25">EFA European Federation of Allergy and Airways Diseases Patients’ Associations, Brussels, Belgium</nlm:aff></affiliation></author><author><name sortKey="Pedersen, S" sort="Pedersen, S" uniqKey="Pedersen S" first="S." last="Pedersen">S. Pedersen</name><affiliation><nlm:aff id="Aff26">University of Southern Denmark, Kolding, Denmark</nlm:aff></affiliation></author><author><name sortKey="Robalo Cordeiro, C" sort="Robalo Cordeiro, C" uniqKey="Robalo Cordeiro C" first="C." last="Robalo-Cordeiro">C. Robalo-Cordeiro</name><affiliation><nlm:aff id="Aff27">Centre of Pneumology, Coimbra University Hospital, Coimbra, Portugal</nlm:aff></affiliation></author><author><name sortKey="Samolinski, B" sort="Samolinski, B" uniqKey="Samolinski B" first="B." last="Samolinski">B. Samolinski</name><affiliation><nlm:aff id="Aff28">Department of Prevention of Environmental Hazards and Allergology, Medical University of Warsaw, Warsaw, Poland</nlm:aff></affiliation></author><author><name sortKey="Strandberg, T" sort="Strandberg, T" uniqKey="Strandberg T" first="T." last="Strandberg">T. Strandberg</name><affiliation><nlm:aff id="Aff29">Helsinki University, Helsinki University Hospital, Helsinki, Finland</nlm:aff></affiliation><affiliation><nlm:aff id="Aff30">Center for Life Course Health Research, University of Oulu, Oulu, Finland</nlm:aff></affiliation><affiliation><nlm:aff id="Aff31">European Union GeriatricMedicine Society, EUGMS, Oslo, Norway</nlm:aff></affiliation></author><author><name sortKey="Valiulis, A" sort="Valiulis, A" uniqKey="Valiulis A" first="A." last="Valiulis">A. Valiulis</name><affiliation><nlm:aff id="Aff32">Center of Quality of Life Research, Vilnius University Clinic of Children’s Diseases, Vilnius University Public Health Institute, Vilnius, Lithuania</nlm:aff></affiliation><affiliation><nlm:aff id="Aff33">European Association of Pediatrics (EAP/UEMS-SP), Brussels, Belgium</nlm:aff></affiliation></author><author><name sortKey="Yorgancioglu, A" sort="Yorgancioglu, A" uniqKey="Yorgancioglu A" first="A." last="Yorgancioglu">A. Yorgancioglu</name><affiliation><nlm:aff id="Aff13">Global Alliance Against Chronic Respiratory Diseases (GARD), Cape Town, South Africa</nlm:aff></affiliation><affiliation><nlm:aff id="Aff18">EIP on AHA Commitment for Action, Lisbon, Portugal</nlm:aff></affiliation><affiliation><nlm:aff id="Aff34">Department of Pulmonology, Celal Bayar University, Manisa, Turkey</nlm:aff></affiliation><affiliation><nlm:aff id="Aff35">Turkish Thoracic Society, Antalya, Turkey</nlm:aff></affiliation></author><author><name sortKey="Zuberbier, T" sort="Zuberbier, T" uniqKey="Zuberbier T" first="T." last="Zuberbier">T. Zuberbier</name><affiliation><nlm:aff id="Aff36">Allergy-Centre-Charité at the Department of Dermatology, Charité - Universitätsmedizin Berlin, Berlin, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="Aff37">Secretary General of the Global Allergy and Asthma European Network (GA²LEN), Berlin, Germany</nlm:aff></affiliation></author><author><name sortKey="Bedbrook, A" sort="Bedbrook, A" uniqKey="Bedbrook A" first="A." last="Bedbrook">A. Bedbrook</name><affiliation><nlm:aff id="Aff2">MACVIA-LR, Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc Roussilon, European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier, France</nlm:aff></affiliation></author><author><name sortKey="Aberer, W" sort="Aberer, W" uniqKey="Aberer W" first="W." last="Aberer">W. Aberer</name><affiliation><nlm:aff id="Aff38">Department of Dermatology, Medical University of Graz, Graz, Austria</nlm:aff></affiliation></author><author><name sortKey="Adachi, M" sort="Adachi, M" uniqKey="Adachi M" first="M." last="Adachi">M. Adachi</name><affiliation><nlm:aff id="Aff39">Department of Clinical Research Center, International University of Health and Welfare/Sanno Hospital, Tokyo, Japan</nlm:aff></affiliation></author><author><name sortKey="Agusti, A" sort="Agusti, A" uniqKey="Agusti A" first="A." last="Agusti">A. Agusti</name><affiliation><nlm:aff id="Aff40">Thorax Institute, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain</nlm:aff></affiliation><affiliation><nlm:aff id="Aff41">CIBER Enfermedades Respiratorias, Barcelona, Spain</nlm:aff></affiliation></author><author><name sortKey="Akdis, C A" sort="Akdis, C A" uniqKey="Akdis C" first="C. A." last="Akdis">C. A. Akdis</name><affiliation><nlm:aff id="Aff42">Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland</nlm:aff></affiliation></author><author><name sortKey="Akdis, M" sort="Akdis, M" uniqKey="Akdis M" first="M." last="Akdis">M. Akdis</name><affiliation><nlm:aff id="Aff42">Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland</nlm:aff></affiliation></author><author><name sortKey="Ankri, J" sort="Ankri, J" uniqKey="Ankri J" first="J." last="Ankri">J. Ankri</name><affiliation><nlm:aff id="Aff3">INSERM, VIMA: Ageing and Chronic Diseases, Epidemiological and Public Health Approaches, U1168, Paris, France</nlm:aff></affiliation><affiliation><nlm:aff id="Aff4">UVSQ, UMR-S 1168, Université Versailles St-Quentin-en-Yvelines, Paris, France</nlm:aff></affiliation></author><author><name sortKey="Alonso, A" sort="Alonso, A" uniqKey="Alonso A" first="A." last="Alonso">A. Alonso</name><affiliation><nlm:aff id="Aff40">Thorax Institute, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain</nlm:aff></affiliation><affiliation><nlm:aff id="Aff41">CIBER Enfermedades Respiratorias, Barcelona, Spain</nlm:aff></affiliation></author><author><name sortKey="Annesi Maesano, I" sort="Annesi Maesano, I" uniqKey="Annesi Maesano I" first="I." last="Annesi-Maesano">I. Annesi-Maesano</name><affiliation><nlm:aff id="Aff43">EPAR U707 INSERM, Paris, France</nlm:aff></affiliation><affiliation><nlm:aff id="Aff331">EPAR UMR-S UPMC, Paris VI, Paris, France</nlm:aff></affiliation></author><author><name sortKey="Ansotegui, I J" sort="Ansotegui, I J" uniqKey="Ansotegui I" first="I. J." last="Ansotegui">I. J. Ansotegui</name><affiliation><nlm:aff id="Aff44">Department of Allergy and Immunology, Hospital Quirón Bizkaia, Erandio, Spain</nlm:aff></affiliation></author><author><name sortKey="Anto, J M" sort="Anto, J M" uniqKey="Anto J" first="J. M." last="Anto">J. M. Anto</name><affiliation><nlm:aff id="Aff45">Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain</nlm:aff></affiliation><affiliation><nlm:aff id="Aff46">Hospital del Mar Research Institute (IMIM), Barcelona, Spain</nlm:aff></affiliation><affiliation><nlm:aff id="Aff47">CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain</nlm:aff></affiliation><affiliation><nlm:aff id="Aff48">Department of Experimental and Health Sciences, University of Pompeu Fabra (UPF), Barcelona, Spain</nlm:aff></affiliation></author><author><name sortKey="Arnavielhe, S" sort="Arnavielhe, S" uniqKey="Arnavielhe S" first="S." last="Arnavielhe">S. Arnavielhe</name><affiliation><nlm:aff id="Aff49">Digi Health, Montpellier, France</nlm:aff></affiliation></author><author><name sortKey="Arshad, H" sort="Arshad, H" uniqKey="Arshad H" first="H." last="Arshad">H. Arshad</name><affiliation><nlm:aff id="Aff50">David Hide Asthma and Allergy Research Centre, Isle of Wight, UK</nlm:aff></affiliation></author><author><name sortKey="Bai, C" sort="Bai, C" uniqKey="Bai C" first="C." last="Bai">C. Bai</name><affiliation><nlm:aff id="Aff51">Shanghai Respiratory Research Institute, Vice President of Respiratory Society, Chinese Medical Association, China and Chinese Alliance Against Lung Cancer, Shanghai, China</nlm:aff></affiliation></author><author><name sortKey="Baiardini, I" sort="Baiardini, I" uniqKey="Baiardini I" first="I." last="Baiardini">I. Baiardini</name><affiliation><nlm:aff id="Aff52">Allergy and Respiratory Diseases Clinic, DIMI, IRCCS AOU San Martino-IST, University of Genoa, Genoa, Italy</nlm:aff></affiliation></author><author><name sortKey="Bachert, C" sort="Bachert, C" uniqKey="Bachert C" first="C." last="Bachert">C. Bachert</name><affiliation><nlm:aff id="Aff53">Upper Airways Research Laboratory, ENT Department, Ghent University Hospital, Ghent, Belgium</nlm:aff></affiliation></author><author><name sortKey="Baigenzhin, A K" sort="Baigenzhin, A K" uniqKey="Baigenzhin A" first="A. K." last="Baigenzhin">A. K. Baigenzhin</name><affiliation><nlm:aff id="Aff54">EuroAsian Respiratory Society, Astana City, Kazakhstan</nlm:aff></affiliation></author><author><name sortKey="Barbara, C" sort="Barbara, C" uniqKey="Barbara C" first="C." last="Barbara">C. Barbara</name><affiliation><nlm:aff id="Aff55">Faculdade de Medicina de Lisboa, Portuguese National Programme for Respiratory Diseases (PNDR), Lisbon, Portugal</nlm:aff></affiliation></author><author><name sortKey="Bateman, E D" sort="Bateman, E D" uniqKey="Bateman E" first="E. D." last="Bateman">E. D. Bateman</name><affiliation><nlm:aff id="Aff56">Department of Medicine, University of Cape Town, Cape Town, South Africa</nlm:aff></affiliation></author><author><name sortKey="Beghe, B" sort="Beghe, B" uniqKey="Beghe B" first="B." last="Beghé">B. Beghé</name><affiliation><nlm:aff id="Aff57">Section of Respiratory Disease, Department of Oncology, Haematology and Respiratory Diseases, University of Modena and Reggio Emilia, Modena, Italy</nlm:aff></affiliation></author><author><name sortKey="Kheder, A Ben" sort="Kheder, A Ben" uniqKey="Kheder A" first="A. Ben" last="Kheder">A. Ben Kheder</name><affiliation><nlm:aff id="Aff58">Service de pneumologie IV, hôpital Abderrahman Mami, Ariana, 2080 Tunis, Tunisia</nlm:aff></affiliation></author><author><name sortKey="Bennoor, K S" sort="Bennoor, K S" uniqKey="Bennoor K" first="K. S." last="Bennoor">K. S. Bennoor</name><affiliation><nlm:aff id="Aff59">Department of Respiratory Medicine, National Institute of Diseases of the Chest and Hospital, Dhaka, Bangladesh</nlm:aff></affiliation></author><author><name sortKey="Benson, M" sort="Benson, M" uniqKey="Benson M" first="M." last="Benson">M. Benson</name><affiliation><nlm:aff id="Aff60">Centre for Individualized Medicine, Department of Pediatrics, Faculty of Medicine, LInköping University, Linköping, Sweden</nlm:aff></affiliation></author><author><name sortKey="Bergmann, K C" sort="Bergmann, K C" uniqKey="Bergmann K" first="K. C." last="Bergmann">K. C. Bergmann</name><affiliation><nlm:aff id="Aff36">Allergy-Centre-Charité at the Department of Dermatology, Charité - Universitätsmedizin Berlin, Berlin, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="Aff37">Secretary General of the Global Allergy and Asthma European Network (GA²LEN), Berlin, Germany</nlm:aff></affiliation></author><author><name sortKey="Bieber, T" sort="Bieber, T" uniqKey="Bieber T" first="T." last="Bieber">T. Bieber</name><affiliation><nlm:aff id="Aff61">Department of Dermatology and Allergy, Rheinische Friedrich-Wilhelms-University Bonn, Bonn, Germany</nlm:aff></affiliation></author><author><name sortKey="Bindslev Jensen, C" sort="Bindslev Jensen, C" uniqKey="Bindslev Jensen C" first="C." last="Bindslev-Jensen">C. Bindslev-Jensen</name><affiliation><nlm:aff id="Aff62">Department of Dermatology and Allergy Centre, Odense University Hospital, Odense, Denmark</nlm:aff></affiliation></author><author><name sortKey="Bjermer, L" sort="Bjermer, L" uniqKey="Bjermer L" first="L." last="Bjermer">L. Bjermer</name><affiliation><nlm:aff id="Aff63">Department of Respiratory Medicine and Allergology, University Hospital, Lund, Sweden</nlm:aff></affiliation></author><author><name sortKey="Blain, H" sort="Blain, H" uniqKey="Blain H" first="H." last="Blain">H. Blain</name><affiliation><nlm:aff id="Aff64">Department of Geriatrics, Montpellier University Hospital, Montpellier, France</nlm:aff></affiliation><affiliation><nlm:aff id="Aff65">EA 2991, Euromov, University Montpellier, Montpellier, France</nlm:aff></affiliation></author><author><name sortKey="Blasi, F" sort="Blasi, F" uniqKey="Blasi F" first="F." last="Blasi">F. Blasi</name><affiliation><nlm:aff id="Aff66">Department of Pathophysiology and Transplantation, IRCCS Fondazione Ca’Granda Ospedale Maggiore Policlinico, University of Milan, Via F. Sforza 35, Milan, Italy</nlm:aff></affiliation></author><author><name sortKey="Boner, A L" sort="Boner, A L" uniqKey="Boner A" first="A. L." last="Boner">A. L. Boner</name><affiliation><nlm:aff id="Aff67">Pediatric Department, University of Verona Hospital, Verona, Italy</nlm:aff></affiliation></author><author><name sortKey="Bonini, M" sort="Bonini, M" uniqKey="Bonini M" first="M." last="Bonini">M. Bonini</name><affiliation><nlm:aff id="Aff68">Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy</nlm:aff></affiliation></author><author><name sortKey="Bonini, S" sort="Bonini, S" uniqKey="Bonini S" first="S." last="Bonini">S. Bonini</name><affiliation><nlm:aff id="Aff69">Second University of Naples and Institute of Translational Medicine, Italian National Research Council, Naples, Italy</nlm:aff></affiliation></author><author><name sortKey="Bosnic Anticevitch, S" sort="Bosnic Anticevitch, S" uniqKey="Bosnic Anticevitch S" first="S." last="Bosnic-Anticevitch">S. Bosnic-Anticevitch</name><affiliation><nlm:aff id="Aff70">Woolcock Institute of Medical Research, University of Sydney and Sydney Local Health District, Glebe, NSW Australia</nlm:aff></affiliation></author><author><name sortKey="Boulet, L P" sort="Boulet, L P" uniqKey="Boulet L" first="L. P." last="Boulet">L. P. Boulet</name><affiliation><nlm:aff id="Aff71">Quebec Heart and Lung Institute, Laval University, Québec City, QC Canada</nlm:aff></affiliation></author><author><name sortKey="Bourret, R" sort="Bourret, R" uniqKey="Bourret R" first="R." last="Bourret">R. Bourret</name><affiliation><nlm:aff id="Aff72">Directeur Général Adjoint, Montpellier University Hospital, Montpellier, France</nlm:aff></affiliation></author><author><name sortKey="Bousquet, P J" sort="Bousquet, P J" uniqKey="Bousquet P" first="P. J." last="Bousquet">P. J. Bousquet</name><affiliation><nlm:aff id="Aff43">EPAR U707 INSERM, Paris, France</nlm:aff></affiliation></author><author><name sortKey="Braido, F" sort="Braido, F" uniqKey="Braido F" first="F." last="Braido">F. Braido</name><affiliation><nlm:aff id="Aff52">Allergy and Respiratory Diseases Clinic, DIMI, IRCCS AOU San Martino-IST, University of Genoa, Genoa, Italy</nlm:aff></affiliation></author><author><name sortKey="Briggs, A H" sort="Briggs, A H" uniqKey="Briggs A" first="A. H." last="Briggs">A. H. Briggs</name><affiliation><nlm:aff id="Aff73">Health Economics and Health Technology Assessment, Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK</nlm:aff></affiliation></author><author><name sortKey="Brightling, C E" sort="Brightling, C E" uniqKey="Brightling C" first="C. E." last="Brightling">C. E. Brightling</name><affiliation><nlm:aff id="Aff74">Respiratory Biomedical Unit, Institute of Lung Health, University Hospitals of Leicester NHS Trust, Leicestershire, UK</nlm:aff></affiliation><affiliation><nlm:aff id="Aff75">Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, UK</nlm:aff></affiliation></author><author><name sortKey="Brozek, J" sort="Brozek, J" uniqKey="Brozek J" first="J." last="Brozek">J. Brozek</name><affiliation><nlm:aff id="Aff76">Department of Clinical Epidemiology and Biostatistics, McMaster University, HSC Room 2C16, 1280 Main Street West Hamilton, Hamilton, Canada</nlm:aff></affiliation></author><author><name sortKey="Buhl, R" sort="Buhl, R" uniqKey="Buhl R" first="R." last="Buhl">R. Buhl</name><affiliation><nlm:aff id="Aff77">Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Mainz, Germany</nlm:aff></affiliation></author><author><name sortKey="Burney, P G" sort="Burney, P G" uniqKey="Burney P" first="P. G." last="Burney">P. G. Burney</name><affiliation><nlm:aff id="Aff78">National Heart and Lung Institute, Imperial College, London, London, UK</nlm:aff></affiliation><affiliation><nlm:aff id="Aff79">Wellcome Centre for Global Health, Imperial College, London, London, UK</nlm:aff></affiliation><affiliation><nlm:aff id="Aff80">MRC-PHE Centre for Environment and Health, Imperial College, London, London, UK</nlm:aff></affiliation></author><author><name sortKey="Bush, A" sort="Bush, A" uniqKey="Bush A" first="A." last="Bush">A. Bush</name><affiliation><nlm:aff id="Aff81">Imperial College and Royal Brompton Hospital, London, UK</nlm:aff></affiliation></author><author><name sortKey="Caballero Fonseca, F" sort="Caballero Fonseca, F" uniqKey="Caballero Fonseca F" first="F." last="Caballero-Fonseca">F. Caballero-Fonseca</name><affiliation><nlm:aff id="Aff82">Centro Medico Docente La Trinidad, Caracas, Venezuela</nlm:aff></affiliation></author><author><name sortKey="Caimmi, D" sort="Caimmi, D" uniqKey="Caimmi D" first="D." last="Caimmi">D. Caimmi</name><affiliation><nlm:aff id="Aff83">Department of Respiratory Diseases, Montpellier University Hospital, Montpellier, France</nlm:aff></affiliation></author><author><name sortKey="Calderon, M A" sort="Calderon, M A" uniqKey="Calderon M" first="M. A." last="Calderon">M. A. Calderon</name><affiliation><nlm:aff id="Aff84">National Heart and Lung Institute, Imperial College London, Royal Brompton Hospital NHS, London, UK</nlm:aff></affiliation></author><author><name sortKey="Calverley, P M" sort="Calverley, P M" uniqKey="Calverley P" first="P. M." last="Calverley">P. M. Calverley</name><affiliation><nlm:aff id="Aff85">Institute of Ageing and Chronic Disease, University of Liverpool and University Hospital Aintree, Liverpool, UK</nlm:aff></affiliation></author><author><name sortKey="Camargos, P A M" sort="Camargos, P A M" uniqKey="Camargos P" first="P. A. M." last="Camargos">P. A. M. Camargos</name><affiliation><nlm:aff id="Aff86">Department of Pediatrics, Medical School, Federal University of Minas Gerais, Belo Horizonte, Brazil</nlm:aff></affiliation></author><author><name sortKey="Canonica, G W" sort="Canonica, G W" uniqKey="Canonica G" first="G. W." last="Canonica">G. W. Canonica</name><affiliation><nlm:aff id="Aff52">Allergy and Respiratory Diseases Clinic, DIMI, IRCCS AOU San Martino-IST, University of Genoa, Genoa, Italy</nlm:aff></affiliation></author><author><name sortKey="Camuzat, T" sort="Camuzat, T" uniqKey="Camuzat T" first="T." last="Camuzat">T. Camuzat</name><affiliation><nlm:aff id="Aff87">Région Languedoc Roussillon, Montpellier, France</nlm:aff></affiliation></author><author><name sortKey="Carlsen, K H" sort="Carlsen, K H" uniqKey="Carlsen K" first="K. H." last="Carlsen">K. H. Carlsen</name><affiliation><nlm:aff id="Aff88">Department of Paediatrics, Oslo University Hospital and University of Oslo, Oslo, Norway</nlm:aff></affiliation></author><author><name sortKey="Carr, W" sort="Carr, W" uniqKey="Carr W" first="W." last="Carr">W. Carr</name><affiliation><nlm:aff id="Aff89">Allergy and Asthma Associates of Southern California, Mission Viejo, CA USA</nlm:aff></affiliation></author><author><name sortKey="Carriazo, A" sort="Carriazo, A" uniqKey="Carriazo A" first="A." last="Carriazo">A. Carriazo</name><affiliation><nlm:aff id="Aff90">Regional Ministry of Equality, Health and Social Policies of Andalusia, Seville, Spain</nlm:aff></affiliation></author><author><name sortKey="Casale, T" sort="Casale, T" uniqKey="Casale T" first="T." last="Casale">T. Casale</name><affiliation><nlm:aff id="Aff91">Division of Allergy/Immunology, University of South Florida, Tampa, FL USA</nlm:aff></affiliation></author><author><name sortKey="Cepeda Sarabia, A M" sort="Cepeda Sarabia, A M" uniqKey="Cepeda Sarabia A" first="A. M." last="Cepeda Sarabia">A. M. Cepeda Sarabia</name><affiliation><nlm:aff id="Aff92">Allergy and Immunology Laboratory, Metropolitan University, Simon Bolivar University, Barranquilla, Colombia</nlm:aff></affiliation><affiliation><nlm:aff id="Aff93">Asma e Immunologia, SLaai, Sociedad Latinoamericana de Allergia, Barranquilla, Colombia</nlm:aff></affiliation></author><author><name sortKey="Chatzi, L" sort="Chatzi, L" uniqKey="Chatzi L" first="L." last="Chatzi">L. Chatzi</name><affiliation><nlm:aff id="Aff94">Department of Social Medicine, Faculty of Medicine, University of Crete, PO Box 2208, Heraklion, 71003 Crete Greece</nlm:aff></affiliation></author><author><name sortKey="Chen, Y Z" sort="Chen, Y Z" uniqKey="Chen Y" first="Y. Z." last="Chen">Y. Z. Chen</name><affiliation><nlm:aff id="Aff95">National Cooperative Group of Paediatric Research on Asthma, Asthma Clinic and Education Center of the Capital Institute of Pediatrics, Peking and Center for Asthma Research and Education, Beijing, China</nlm:aff></affiliation></author><author><name sortKey="Chiron, R" sort="Chiron, R" uniqKey="Chiron R" first="R." last="Chiron">R. Chiron</name><affiliation><nlm:aff id="Aff83">Department of Respiratory Diseases, Montpellier University Hospital, Montpellier, France</nlm:aff></affiliation></author><author><name sortKey="Chkhartishvili, E" sort="Chkhartishvili, E" uniqKey="Chkhartishvili E" first="E." last="Chkhartishvili">E. Chkhartishvili</name><affiliation><nlm:aff id="Aff96">Chachava Clinic, David Tvildiani Medical University-AIETI Medical School, Grigol Robakidze University, Tbilisi, Georgia</nlm:aff></affiliation></author><author><name sortKey="Chuchalin, A G" sort="Chuchalin, A G" uniqKey="Chuchalin A" first="A. G." last="Chuchalin">A. G. Chuchalin</name><affiliation><nlm:aff id="Aff17">GARD Executive Committee, Bahia, Brazil</nlm:aff></affiliation><affiliation><nlm:aff id="Aff97">Pulmonolory Research Institute FMBA, Moscow, Russia</nlm:aff></affiliation></author><author><name sortKey="Chung, K F" sort="Chung, K F" uniqKey="Chung K" first="K. F." last="Chung">K. F. Chung</name><affiliation><nlm:aff id="Aff98">National Heart and Lung Institute, Imperial College, London, London, UK</nlm:aff></affiliation></author><author><name sortKey="Ciprandi, G" sort="Ciprandi, G" uniqKey="Ciprandi G" first="G." last="Ciprandi">G. Ciprandi</name><affiliation><nlm:aff id="Aff99">Medicine Department, IRCCS-Azienda Ospedaliera Universitaria San Martino, Genoa, Italy</nlm:aff></affiliation></author><author><name sortKey="Cirule, I" sort="Cirule, I" uniqKey="Cirule I" first="I." last="Cirule">I. Cirule</name><affiliation><nlm:aff id="Aff100">Latvian Allergy Association, Riga, Latvia</nlm:aff></affiliation></author><author><name sortKey="Cox, L" sort="Cox, L" uniqKey="Cox L" first="L." last="Cox">L. Cox</name><affiliation><nlm:aff id="Aff101">Department of Medicine, Nova Southeastern University, Davie, FL USA</nlm:aff></affiliation></author><author><name sortKey="Costa, D J" sort="Costa, D J" uniqKey="Costa D" first="D. J." last="Costa">D. J. Costa</name><affiliation><nlm:aff id="Aff2">MACVIA-LR, Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc Roussilon, European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier, France</nlm:aff></affiliation><affiliation><nlm:aff id="Aff12">Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Custovic, A" sort="Custovic, A" uniqKey="Custovic A" first="A." last="Custovic">A. Custovic</name><affiliation><nlm:aff id="Aff102">Department of Paediatrics, Imperial College London, London, UK</nlm:aff></affiliation></author><author><name sortKey="Dahl, R" sort="Dahl, R" uniqKey="Dahl R" first="R." last="Dahl">R. Dahl</name><affiliation><nlm:aff id="Aff62">Department of Dermatology and Allergy Centre, Odense University Hospital, Odense, Denmark</nlm:aff></affiliation></author><author><name sortKey="Dahlen, S E" sort="Dahlen, S E" uniqKey="Dahlen S" first="S. E." last="Dahlen">S. E. Dahlen</name><affiliation><nlm:aff id="Aff103">The Centre for Allergy Research, The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden</nlm:aff></affiliation></author><author><name sortKey="Darsow, U" sort="Darsow, U" uniqKey="Darsow U" first="U." last="Darsow">U. Darsow</name><affiliation><nlm:aff id="Aff104">Department of Dermatology and Allergy, Technische Universität München, Munich, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="Aff105">ZAUM-Center for Allergy and Environment, Helmholtz Center Munich, Technische Universität München, Munich, Germany</nlm:aff></affiliation></author><author><name sortKey="De Carlo, G" sort="De Carlo, G" uniqKey="De Carlo G" first="G." last="De Carlo">G. De Carlo</name><affiliation><nlm:aff id="Aff25">EFA European Federation of Allergy and Airways Diseases Patients’ Associations, Brussels, Belgium</nlm:aff></affiliation></author><author><name sortKey="De Blay, F" sort="De Blay, F" uniqKey="De Blay F" first="F." last="De Blay">F. De Blay</name><affiliation><nlm:aff id="Aff106">Allergy Division, Chest Disease Department, University Hospital of Strasbourg, Strasbourg, France</nlm:aff></affiliation></author><author><name sortKey="Dedeu, T" sort="Dedeu, T" uniqKey="Dedeu T" first="T." last="Dedeu">T. Dedeu</name><affiliation><nlm:aff id="Aff107">EUREGHA, European Regional and Local Health Association, Brussels, Belgium</nlm:aff></affiliation><affiliation><nlm:aff id="Aff108">University of Edinburgh, Edinburgh, UK</nlm:aff></affiliation></author><author><name sortKey="Deleanu, D" sort="Deleanu, D" uniqKey="Deleanu D" first="D." last="Deleanu">D. Deleanu</name><affiliation><nlm:aff id="Aff109">Allergology and Immunology Discipline, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania</nlm:aff></affiliation></author><author><name sortKey="De Manuel Keenoy, E" sort="De Manuel Keenoy, E" uniqKey="De Manuel Keenoy E" first="E." last="De Manuel Keenoy">E. De Manuel Keenoy</name><affiliation><nlm:aff id="Aff110">Kronikgune, Bilbao, Basque Region Spain</nlm:aff></affiliation></author><author><name sortKey="Demoly, P" sort="Demoly, P" uniqKey="Demoly P" first="P." last="Demoly">P. Demoly</name><affiliation><nlm:aff id="Aff43">EPAR U707 INSERM, Paris, France</nlm:aff></affiliation><affiliation><nlm:aff id="Aff83">Department of Respiratory Diseases, Montpellier University Hospital, Montpellier, France</nlm:aff></affiliation></author><author><name sortKey="Denburg, J A" sort="Denburg, J A" uniqKey="Denburg J" first="J. A." last="Denburg">J. A. Denburg</name><affiliation><nlm:aff id="Aff111">Department of Medicine, Division of Clinical Immunology and Allergy, McMaster University, Hamilton, ON Canada</nlm:aff></affiliation></author><author><name sortKey="Devillier, P" sort="Devillier, P" uniqKey="Devillier P" first="P." last="Devillier">P. Devillier</name><affiliation><nlm:aff id="Aff112">Laboratoire de Pharmacologie Respiratoire UPRES EA220, Hôpital Foch, Suresnes Université Versailles Saint-Quentin, Suresnes, France</nlm:aff></affiliation></author><author><name sortKey="Didier, A" sort="Didier, A" uniqKey="Didier A" first="A." last="Didier">A. Didier</name><affiliation><nlm:aff id="Aff113">Respiratory Diseases Department, Rangueil-Larrey Hospital, Toulouse, France</nlm:aff></affiliation></author><author><name sortKey="Dinh Xuan, A T" sort="Dinh Xuan, A T" uniqKey="Dinh Xuan A" first="A. T." last="Dinh-Xuan">A. T. Dinh-Xuan</name><affiliation><nlm:aff id="Aff114">Service de physiologie respiratoire, Hôpital Cochin, Université Paris-Descartes, Assistance publique-Hôpitaux de Paris, Paris, France</nlm:aff></affiliation></author><author><name sortKey="Djukanovic, R" sort="Djukanovic, R" uniqKey="Djukanovic R" first="R." last="Djukanovic">R. Djukanovic</name><affiliation><nlm:aff id="Aff115">NIHR Southampton Respiratory Biomedical Research Unit, Faculty of Medicine, University Southampton, Southampton, UK</nlm:aff></affiliation></author><author><name sortKey="Dokic, D" sort="Dokic, D" uniqKey="Dokic D" first="D." last="Dokic">D. Dokic</name><affiliation><nlm:aff id="Aff116">Medical Faculty Skopje, University Clinic of Pulmology and Allergy, Skopje, Republic Macedonia</nlm:aff></affiliation></author><author><name sortKey="Douagui, H" sort="Douagui, H" uniqKey="Douagui H" first="H." last="Douagui">H. Douagui</name><affiliation><nlm:aff id="Aff117">Service de Pneumo-Allergologie, Centre Hospitalo-Universitaire de Béni-Messous, Algers, Algeria</nlm:aff></affiliation></author><author><name sortKey="Dray, G" sort="Dray, G" uniqKey="Dray G" first="G." last="Dray">G. Dray</name><affiliation><nlm:aff id="Aff118">Ecole des Mines, Alès, France</nlm:aff></affiliation></author><author><name sortKey="Dubakiene, R" sort="Dubakiene, R" uniqKey="Dubakiene R" first="R." last="Dubakiene">R. Dubakiene</name><affiliation><nlm:aff id="Aff119">Medical Faculty, Vilnius University, Vilnius, Lithuania</nlm:aff></affiliation></author><author><name sortKey="Durham, S R" sort="Durham, S R" uniqKey="Durham S" first="S. R." last="Durham">S. R. Durham</name><affiliation><nlm:aff id="Aff120">Allergy and Clinical Immunology Section, National Heart and Lung Institute, Imperial College London, London, UK</nlm:aff></affiliation></author><author><name sortKey="Dykewicz, M S" sort="Dykewicz, M S" uniqKey="Dykewicz M" first="M. S." last="Dykewicz">M. S. Dykewicz</name><affiliation><nlm:aff id="Aff121">Section of Allergy and Immunology, Saint Louis University School of Medicine, Saint Louis, MO USA</nlm:aff></affiliation></author><author><name sortKey="El Gamal, Y" sort="El Gamal, Y" uniqKey="El Gamal Y" first="Y." last="El-Gamal">Y. El-Gamal</name><affiliation><nlm:aff id="Aff122">Pediatric Allergy and Immunology Unit, Ain Shams University, Cairo, Egypt</nlm:aff></affiliation></author><author><name sortKey="Emuzyte, R" sort="Emuzyte, R" uniqKey="Emuzyte R" first="R." last="Emuzyte">R. Emuzyte</name><affiliation><nlm:aff id="Aff123">Clinic of Children’s Diseases, Faculty of Medicine, Vilnius University, Vilnius, Lithuania</nlm:aff></affiliation></author><author><name sortKey="Fabbri, L M" sort="Fabbri, L M" uniqKey="Fabbri L" first="L. M." last="Fabbri">L. M. Fabbri</name><affiliation><nlm:aff id="Aff124">Modena University, Modena, Italy</nlm:aff></affiliation></author><author><name sortKey="Fletcher, M" sort="Fletcher, M" uniqKey="Fletcher M" first="M." last="Fletcher">M. Fletcher</name><affiliation><nlm:aff id="Aff125">Education for Health, Warwick, UK</nlm:aff></affiliation></author><author><name sortKey="Fiocchi, A" sort="Fiocchi, A" uniqKey="Fiocchi A" first="A." last="Fiocchi">A. Fiocchi</name><affiliation><nlm:aff id="Aff126">Division of Allergy, Department of Pediatric Medicine, The Bambino Gesù Children’s Research Hospital Holy See, Rome, Italy</nlm:aff></affiliation></author><author><name sortKey="Fink Wagner, A" sort="Fink Wagner, A" uniqKey="Fink Wagner A" first="A." last="Fink Wagner">A. Fink Wagner</name><affiliation><nlm:aff id="Aff127">Global Allergy and Asthma Platform (GAAPP), Altgasse 8-10, 1130 Vienna, Austria</nlm:aff></affiliation></author><author><name sortKey="Fonseca, J" sort="Fonseca, J" uniqKey="Fonseca J" first="J." last="Fonseca">J. Fonseca</name><affiliation><nlm:aff id="Aff128">Center for Health Technology and Services Research - CINTESIS, Faculdade de Medicina, Universidade do Porto, Porto, Portugal</nlm:aff></affiliation><affiliation><nlm:aff id="Aff129">Allergy Unit, CUF Porto Instituto & Hospital, Porto, Portugal</nlm:aff></affiliation></author><author><name sortKey="Fokkens, W J" sort="Fokkens, W J" uniqKey="Fokkens W" first="W. J." last="Fokkens">W. J. Fokkens</name><affiliation><nlm:aff id="Aff130">Department of Otorhinolaryngology, Academic Medical Centre, Amsterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Forastiere, F" sort="Forastiere, F" uniqKey="Forastiere F" first="F." last="Forastiere">F. Forastiere</name><affiliation><nlm:aff id="Aff131">Department of Epidemiology, Regional Health Service Lazio Region, Rome, Italy</nlm:aff></affiliation></author><author><name sortKey="Frith, P" sort="Frith, P" uniqKey="Frith P" first="P." last="Frith">P. Frith</name><affiliation><nlm:aff id="Aff132">Repatriation General Hospital, Adelaide, SOUTH AUSTRALIA Australia</nlm:aff></affiliation></author><author><name sortKey="Gaga, M" sort="Gaga, M" uniqKey="Gaga M" first="M." last="Gaga">M. Gaga</name><affiliation><nlm:aff id="Aff133">Athens Chest Hospital, Athens, Greece</nlm:aff></affiliation></author><author><name sortKey="Gamkrelidze, A" sort="Gamkrelidze, A" uniqKey="Gamkrelidze A" first="A." last="Gamkrelidze">A. Gamkrelidze</name><affiliation><nlm:aff id="Aff134">National Center for Disease Control and Public Health of Georgia, Tbilisi, Georgia</nlm:aff></affiliation></author><author><name sortKey="Garces, J" sort="Garces, J" uniqKey="Garces J" first="J." last="Garces">J. Garces</name><affiliation><nlm:aff id="Aff135">Polibienestar Research Institute, University of Valencia, Valencia, Spain</nlm:aff></affiliation></author><author><name sortKey="Garcia Aymerich, J" sort="Garcia Aymerich, J" uniqKey="Garcia Aymerich J" first="J." last="Garcia-Aymerich">J. Garcia-Aymerich</name><affiliation><nlm:aff id="Aff45">Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain</nlm:aff></affiliation><affiliation><nlm:aff id="Aff46">Hospital del Mar Research Institute (IMIM), Barcelona, Spain</nlm:aff></affiliation><affiliation><nlm:aff id="Aff47">CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain</nlm:aff></affiliation><affiliation><nlm:aff id="Aff48">Department of Experimental and Health Sciences, University of Pompeu Fabra (UPF), Barcelona, Spain</nlm:aff></affiliation></author><author><name sortKey="Gemicio Lu, B" sort="Gemicio Lu, B" uniqKey="Gemicio Lu B" first="B." last="Gemicio Lu">B. Gemicio Lu</name><affiliation><nlm:aff id="Aff136">Department of Pulmonary Diseases, Cerrahpasa Faculty of Medicine, Istanbul University, Istanbul, Turkey</nlm:aff></affiliation></author><author><name sortKey="Gereda, J E" sort="Gereda, J E" uniqKey="Gereda J" first="J. E." last="Gereda">J. E. Gereda</name><affiliation><nlm:aff id="Aff137">Allergy and Immunology Division, Clinica Ricardo Palma, Lima, Peru</nlm:aff></affiliation></author><author><name sortKey="Gonzalez Diaz, S" sort="Gonzalez Diaz, S" uniqKey="Gonzalez Diaz S" first="S." last="González Diaz">S. González Diaz</name><affiliation><nlm:aff id="Aff138">Universidad Autónoma de Nuevo León, San Nicolás De La Garza, Mexico</nlm:aff></affiliation></author><author><name sortKey="Gotua, M" sort="Gotua, M" uniqKey="Gotua M" first="M." last="Gotua">M. Gotua</name><affiliation><nlm:aff id="Aff139">Center of Allergy and Immunology, Georgian Association of Allergology and Clinical Immunology, Tbilisi, Georgia</nlm:aff></affiliation></author><author><name sortKey="Grisle, I" sort="Grisle, I" uniqKey="Grisle I" first="I." last="Grisle">I. Grisle</name><affiliation><nlm:aff id="Aff140">Latvian Association of Allergists, Center of Tuberculosis and Lung Diseases, Riga, Latvia</nlm:aff></affiliation></author><author><name sortKey="Grouse, L" sort="Grouse, L" uniqKey="Grouse L" first="L." last="Grouse">L. Grouse</name><affiliation><nlm:aff id="Aff141">Faculty of the Department of Neurology, University of Washington School of Medicine, St. Louis, MO USA</nlm:aff></affiliation></author><author><name sortKey="Gutter, Z" sort="Gutter, Z" uniqKey="Gutter Z" first="Z." last="Gutter">Z. Gutter</name><affiliation><nlm:aff id="Aff142">University Hospital Olomouc – National eHealth Centre, Olomouc, Czech Republic</nlm:aff></affiliation></author><author><name sortKey="Guzman, M A" sort="Guzman, M A" uniqKey="Guzman M" first="M. A." last="Guzmán">M. A. Guzmán</name><affiliation><nlm:aff id="Aff143">Immunology and Allergy Division, Clinical Hospital, University of Chile, Santiago, Chile</nlm:aff></affiliation></author><author><name sortKey="Heaney, L G" sort="Heaney, L G" uniqKey="Heaney L" first="L. G." last="Heaney">L. G. Heaney</name><affiliation><nlm:aff id="Aff144">Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University Belfast, Belfast, UK</nlm:aff></affiliation></author><author><name sortKey="Hellquist Dahl, B" sort="Hellquist Dahl, B" uniqKey="Hellquist Dahl B" first="B." last="Hellquist-Dahl">B. Hellquist-Dahl</name><affiliation><nlm:aff id="Aff145">Department of Respiratory Diseases, Odense University Hospital, Odense, Denmark</nlm:aff></affiliation></author><author><name sortKey="Henderson, D" sort="Henderson, D" uniqKey="Henderson D" first="D." last="Henderson">D. Henderson</name><affiliation><nlm:aff id="Aff6">EIP on AHA, European Innovation Partnership on Active and Healthy Ageing, Reference Site, Scottish Centre for Telehealth and Telecare, NHS 24, Glasgow, UK</nlm:aff></affiliation></author><author><name sortKey="Hendry, A" sort="Hendry, A" uniqKey="Hendry A" first="A." last="Hendry">A. Hendry</name><affiliation><nlm:aff id="Aff146">NHS Scotland, Edinburgh, Scotland, UK</nlm:aff></affiliation></author><author><name sortKey="Heinrich, J" sort="Heinrich, J" uniqKey="Heinrich J" first="J." last="Heinrich">J. Heinrich</name><affiliation><nlm:aff id="Aff147">Institute of Epidemiology I, German Research Centre for Environmental Health, Helmholtz Zentrum München, Neuherberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Heve, D" sort="Heve, D" uniqKey="Heve D" first="D." last="Heve">D. Heve</name><affiliation><nlm:aff id="Aff2">MACVIA-LR, Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc Roussilon, European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier, France</nlm:aff></affiliation><affiliation><nlm:aff id="Aff148">Agence Régionale de Santé, 34067 Montpellier Cedex 2, France</nlm:aff></affiliation></author><author><name sortKey="Horak, F" sort="Horak, F" uniqKey="Horak F" first="F." last="Horak">F. Horak</name><affiliation><nlm:aff id="Aff149">Vienna Challenge Chamber, Vienna, Austria</nlm:aff></affiliation></author><author><name sortKey="Hourihane, J O B" sort="Hourihane, J O B" uniqKey="Hourihane J" first="J. O B." last="Hourihane">J. O B. Hourihane</name><affiliation><nlm:aff id="Aff150">Department of Paediatrics and Child Health, University College Cork, Cork, Ireland</nlm:aff></affiliation></author><author><name sortKey="Howarth, P" sort="Howarth, P" uniqKey="Howarth P" first="P." last="Howarth">P. Howarth</name><affiliation><nlm:aff id="Aff151">University of Southampton Faculty of Medicine, University Hospital Southampton, Southampton, UK</nlm:aff></affiliation></author><author><name sortKey="Humbert, M" sort="Humbert, M" uniqKey="Humbert M" first="M." last="Humbert">M. Humbert</name><affiliation><nlm:aff id="Aff152">Service de Pneumologie, Hôpital Bicêtre, Inserm UMR_S999, Université Paris-Sud, Le Kremlin Bicêtre, France</nlm:aff></affiliation></author><author><name sortKey="Hyland, M E" sort="Hyland, M E" uniqKey="Hyland M" first="M. E." last="Hyland">M. E. Hyland</name><affiliation><nlm:aff id="Aff153">School of Psychology, Plymouth University, Plymouth, UK</nlm:aff></affiliation></author><author><name sortKey="Illario, M" sort="Illario, M" uniqKey="Illario M" first="M." last="Illario">M. Illario</name><affiliation><nlm:aff id="Aff154">Federico II University Hospital/Campania RS, Naples, Italy</nlm:aff></affiliation></author><author><name sortKey="Ivancevich, J C" sort="Ivancevich, J C" uniqKey="Ivancevich J" first="J. C." last="Ivancevich">J. C. Ivancevich</name><affiliation><nlm:aff id="Aff155">Servicio de Alergia e Immunologia, Clinica Santa Isabel, Buenos Aires, Argentina</nlm:aff></affiliation></author><author><name sortKey="Jardim, J R" sort="Jardim, J R" uniqKey="Jardim J" first="J. R." last="Jardim">J. R. Jardim</name><affiliation><nlm:aff id="Aff156">Universidade Federal de Sao Paulo, São Paulo, Brazil</nlm:aff></affiliation></author><author><name sortKey="Jares, E J" sort="Jares, E J" uniqKey="Jares E" first="E. J." last="Jares">E. J. Jares</name><affiliation><nlm:aff id="Aff157">Libra Foundation, Buenos Aires, Argentina</nlm:aff></affiliation></author><author><name sortKey="Jeandel, C" sort="Jeandel, C" uniqKey="Jeandel C" first="C." last="Jeandel">C. Jeandel</name><affiliation><nlm:aff id="Aff2">MACVIA-LR, Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc Roussilon, European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier, France</nlm:aff></affiliation><affiliation><nlm:aff id="Aff64">Department of Geriatrics, Montpellier University Hospital, Montpellier, France</nlm:aff></affiliation></author><author><name sortKey="Jenkins, C" sort="Jenkins, C" uniqKey="Jenkins C" first="C." last="Jenkins">C. Jenkins</name><affiliation><nlm:aff id="Aff158">The George Institute for Global Health, The University of Sydney, Camperdown, Australia</nlm:aff></affiliation></author><author><name sortKey="Johnston, S L" sort="Johnston, S L" uniqKey="Johnston S" first="S. L." last="Johnston">S. L. Johnston</name><affiliation><nlm:aff id="Aff159">Airway Disease Infection Section, National Heart and Lung Institute, Imperial College, London, London, UK</nlm:aff></affiliation><affiliation><nlm:aff id="Aff160">MRC and Asthma UK Centre in Allergic Mechanisms of Asthma, London, UK</nlm:aff></affiliation></author><author><name sortKey="Jonquet, O" sort="Jonquet, O" uniqKey="Jonquet O" first="O." last="Jonquet">O. Jonquet</name><affiliation><nlm:aff id="Aff161">Medical Commission, Montpellier University Hospital, Montpellier, France</nlm:aff></affiliation></author><author><name sortKey="Julge, K" sort="Julge, K" uniqKey="Julge K" first="K." last="Julge">K. Julge</name><affiliation><nlm:aff id="Aff162">Children’s Clinic of Tartu University Hospital, Tartu, Estonia</nlm:aff></affiliation></author><author><name sortKey="Jung, K S" sort="Jung, K S" uniqKey="Jung K" first="K. S." last="Jung">K. S. Jung</name><affiliation><nlm:aff id="Aff163">Hallym University College of Medicine, Hallym University Sacred Heart Hospital, Gyeonggi-Do, South Korea</nlm:aff></affiliation></author><author><name sortKey="Just, J" sort="Just, J" uniqKey="Just J" first="J." last="Just">J. Just</name><affiliation><nlm:aff id="Aff164">Allergology Department, Centre de l’Asthme et des Allergies, Hôpital d’Enfants Armand-Trousseau (APHP), Paris, France</nlm:aff></affiliation><affiliation><nlm:aff id="Aff165">Sorbonne Universités, UPMC Univ Paris 06, UMR_S 1136, Institut Pierre Louis d’Epidémiologie et de Santé Publique, Equipe EPAR, 75013 Paris, France</nlm:aff></affiliation></author><author><name sortKey="Kaidashev, I" sort="Kaidashev, I" uniqKey="Kaidashev I" first="I." last="Kaidashev">I. Kaidashev</name><affiliation><nlm:aff id="Aff166">Ukrainian Medical Stomatological Academy, Poltava, Ukraine</nlm:aff></affiliation></author><author><name sortKey="Kaitov, M R" sort="Kaitov, M R" uniqKey="Kaitov M" first="M. R." last="Kaitov">M. R. Kaitov</name><affiliation><nlm:aff id="Aff167">Federal Medicobiological Agency, Laboratory of Molecular Immunology, Institute of Immunology, National Research Center, Moscow, Russian Federation</nlm:aff></affiliation></author><author><name sortKey="Kalayci, O" sort="Kalayci, O" uniqKey="Kalayci O" first="O." last="Kalayci">O. Kalayci</name><affiliation><nlm:aff id="Aff168">Pediatric Allergy and Asthma Unit, Hacettepe University School of Medicine, Ankara, Turkey</nlm:aff></affiliation></author><author><name sortKey="Kalyoncu, A F" sort="Kalyoncu, A F" uniqKey="Kalyoncu A" first="A. F." last="Kalyoncu">A. F. Kalyoncu</name><affiliation><nlm:aff id="Aff169">Immunology and Allergy Division, Department of Chest Diseases, School of Medicine, Hacettepe University, Ankara, Turkey</nlm:aff></affiliation></author><author><name sortKey="Keil, T" sort="Keil, T" uniqKey="Keil T" first="T." last="Keil">T. Keil</name><affiliation><nlm:aff id="Aff170">Institute of Social Medicine, Epidemiology and Health Economics, Charité - Universitätsmedizin Berlin, Berlin, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="Aff171">Institute for Clinical Epidemiology and Biometry, University of Würzburg, Würzburg, Germany</nlm:aff></affiliation></author><author><name sortKey="Keith, P K" sort="Keith, P K" uniqKey="Keith P" first="P. K." last="Keith">P. K. Keith</name><affiliation><nlm:aff id="Aff172">Department of Medicine, McMaster University, Health Sciences Centre 3V47, 1280 Main Street West, Hamilton, Canada</nlm:aff></affiliation></author><author><name sortKey="Klimek, L" sort="Klimek, L" uniqKey="Klimek L" first="L." last="Klimek">L. Klimek</name><affiliation><nlm:aff id="Aff173">Center for Rhinology and Allergology, Wiesbaden, Germany</nlm:aff></affiliation></author><author><name sortKey="Koffi N Oran, B" sort="Koffi N Oran, B" uniqKey="Koffi N Oran B" first="B." last="Koffi N Oran">B. Koffi N Oran</name><affiliation><nlm:aff id="Aff174">Société de Pneumologie de Langue Française, Espace francophone de Pneumologie, Paris, France</nlm:aff></affiliation></author><author><name sortKey="Kolek, V" sort="Kolek, V" uniqKey="Kolek V" first="V." last="Kolek">V. Kolek</name><affiliation><nlm:aff id="Aff175">Department of Respiratory Medicine, Faculty of Medicine and Dentistry, University Hospital Olomouc, Olomouc, Czech Republic</nlm:aff></affiliation></author><author><name sortKey="Koppelman, G H" sort="Koppelman, G H" uniqKey="Koppelman G" first="G. H." last="Koppelman">G. H. Koppelman</name><affiliation><nlm:aff id="Aff176">GRIACResearch Institute, Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children’s Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Kowalski, M L" sort="Kowalski, M L" uniqKey="Kowalski M" first="M. L." last="Kowalski">M. L. Kowalski</name><affiliation><nlm:aff id="Aff177">Department of Immunology, Rheumatology and Allergy, Medical University of Lodz, and HARC, Lodz, Poland</nlm:aff></affiliation></author><author><name sortKey="Kull, I" sort="Kull, I" uniqKey="Kull I" first="I." last="Kull">I. Kull</name><affiliation><nlm:aff id="Aff178">Sachs’ Children’s Hospital, Stockholm, Sweden</nlm:aff></affiliation><affiliation><nlm:aff id="Aff179">Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden</nlm:aff></affiliation></author><author><name sortKey="Kuna, P" sort="Kuna, P" uniqKey="Kuna P" first="P." last="Kuna">P. Kuna</name><affiliation><nlm:aff id="Aff180">Division of Internal Medicine, Asthma and Allergy, Barlicki University Hospital, Medical University of Lodz, Lodz, Poland</nlm:aff></affiliation></author><author><name sortKey="Kvedariene, V" sort="Kvedariene, V" uniqKey="Kvedariene V" first="V." last="Kvedariene">V. Kvedariene</name><affiliation><nlm:aff id="Aff181">Clinic of Infectious, Chest Diseases, Dermatology and Allergology, Vilnius University, Vilnius, Lithuania</nlm:aff></affiliation></author><author><name sortKey="Lambrecht, B" sort="Lambrecht, B" uniqKey="Lambrecht B" first="B." last="Lambrecht">B. Lambrecht</name><affiliation><nlm:aff id="Aff182">VIB Inflammation Research Center, Ghent University, Ghent, Belgium</nlm:aff></affiliation></author><author><name sortKey="Lau, S" sort="Lau, S" uniqKey="Lau S" first="S." last="Lau">S. Lau</name><affiliation><nlm:aff id="Aff183">Department for Pediatric Pneumology and Immunology, Charité Medical University, Berlin, Germany</nlm:aff></affiliation></author><author><name sortKey="Larenas Linnemann, D" sort="Larenas Linnemann, D" uniqKey="Larenas Linnemann D" first="D." last="Larenas-Linnemann">D. Larenas-Linnemann</name><affiliation><nlm:aff id="Aff184">Clínica de Alergia, Asma y Pediatría, Hospital Médica Sur, Ciudad De México, Mexico</nlm:aff></affiliation></author><author><name sortKey="Laune, D" sort="Laune, D" uniqKey="Laune D" first="D." last="Laune">D. Laune</name><affiliation><nlm:aff id="Aff49">Digi Health, Montpellier, France</nlm:aff></affiliation></author><author><name sortKey="Le, L T T" sort="Le, L T T" uniqKey="Le L" first="L. T. T." last="Le">L. T. T. Le</name><affiliation><nlm:aff id="Aff185">University of Medicine and Pharmacy, Hochiminh City, Vietnam</nlm:aff></affiliation></author><author><name sortKey="Lieberman, P" sort="Lieberman, P" uniqKey="Lieberman P" first="P." last="Lieberman">P. Lieberman</name><affiliation><nlm:aff id="Aff186">Divisions of Allergy and Immunology, Departments of Internal Medicine and Pediatrics, University of Tennessee College of Medicine, Germantown, TN USA</nlm:aff></affiliation></author><author><name sortKey="Lipworth, B" sort="Lipworth, B" uniqKey="Lipworth B" first="B." last="Lipworth">B. Lipworth</name><affiliation><nlm:aff id="Aff187">Scottish Centre for Respiratory Research, Cardiovascular and Diabetes Medicine, Medical Research Institute, Ninewells Hospital, University of Dundee, Dundee, UK</nlm:aff></affiliation></author><author><name sortKey="Li, J" sort="Li, J" uniqKey="Li J" first="J." last="Li">J. Li</name><affiliation><nlm:aff id="Aff188">State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120 China</nlm:aff></affiliation></author><author><name sortKey="Lodrup Carlsen, K" sort="Lodrup Carlsen, K" uniqKey="Lodrup Carlsen K" first="K." last="Lodrup Carlsen">K. Lodrup Carlsen</name><affiliation><nlm:aff id="Aff189">Department of Paediatrics, Oslo University Hospital, Oslo, Norway</nlm:aff></affiliation><affiliation><nlm:aff id="Aff190">Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway</nlm:aff></affiliation></author><author><name sortKey="Louis, R" sort="Louis, R" uniqKey="Louis R" first="R." last="Louis">R. Louis</name><affiliation><nlm:aff id="Aff191">Department of Pulmonary Medicine, CHU Sart-Tilman, Liege, Belgium</nlm:aff></affiliation></author><author><name sortKey="Macnee, W" sort="Macnee, W" uniqKey="Macnee W" first="W." last="Macnee">W. Macnee</name><affiliation><nlm:aff id="Aff192">Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, UK</nlm:aff></affiliation></author><author><name sortKey="Magard, Y" sort="Magard, Y" uniqKey="Magard Y" first="Y." last="Magard">Y. Magard</name><affiliation><nlm:aff id="Aff193">Service de Pneumo-allergologie, Hôpital Saint-Joseph, Paris, France</nlm:aff></affiliation></author><author><name sortKey="Magnan, A" sort="Magnan, A" uniqKey="Magnan A" first="A." last="Magnan">A. Magnan</name><affiliation><nlm:aff id="Aff194">Service de Pneumologie, UMR INSERM, UMR1087and CNR 6291, l’institut du thorax, University of Nantes, Nantes, France</nlm:aff></affiliation></author><author><name sortKey="Mahboub, B" sort="Mahboub, B" uniqKey="Mahboub B" first="B." last="Mahboub">B. Mahboub</name><affiliation><nlm:aff id="Aff195">Department of Pulmonary Medicine, Rashid Hospital, Dubai, UAE</nlm:aff></affiliation></author><author><name sortKey="Mair, A" sort="Mair, A" uniqKey="Mair A" first="A." last="Mair">A. Mair</name><affiliation><nlm:aff id="Aff196">Scottish Government Health Department, eHealth and Pharmaceuticals, Edinburgh, UK</nlm:aff></affiliation></author><author><name sortKey="Majer, I" sort="Majer, I" uniqKey="Majer I" first="I." last="Majer">I. Majer</name><affiliation><nlm:aff id="Aff197">Department of Respiratory Medicine, University of Bratislava, Bratislava, Slovakia</nlm:aff></affiliation></author><author><name sortKey="Makela, M J" sort="Makela, M J" uniqKey="Makela M" first="M. J." last="Makela">M. J. Makela</name><affiliation><nlm:aff id="Aff19">Skin and Allergy Hospital, Helsinki University Hospital, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Manning, P" sort="Manning, P" uniqKey="Manning P" first="P." last="Manning">P. Manning</name><affiliation><nlm:aff id="Aff198">Department of Medicine (RCSI), Bon Secours Hospital, Glasnevin, Dublin, Ireland</nlm:aff></affiliation></author><author><name sortKey="Mara, S" sort="Mara, S" uniqKey="Mara S" first="S." last="Mara">S. Mara</name><affiliation><nlm:aff id="Aff199">Cardiovascular and Thoracic Department, AOU Città della Salute e della Scienza di Torino, Turin, Italy</nlm:aff></affiliation></author><author><name sortKey="Marshall, G D" sort="Marshall, G D" uniqKey="Marshall G" first="G. D." last="Marshall">G. D. Marshall</name><affiliation><nlm:aff id="Aff200">Division of Clinical Immunology and Allergy, Laboratory of Behavioral Immunology Research, The University of Mississippi Medical Center, Jackson, MS USA</nlm:aff></affiliation></author><author><name sortKey="Masjedi, M R" sort="Masjedi, M R" uniqKey="Masjedi M" first="M. R." last="Masjedi">M. R. Masjedi</name><affiliation><nlm:aff id="Aff201">Respiratory Medicine Research, Shahid Beheshti University of Medical Sciences, Tehran, Iran</nlm:aff></affiliation></author><author><name sortKey="Matignon, P" sort="Matignon, P" uniqKey="Matignon P" first="P." last="Matignon">P. Matignon</name><affiliation><nlm:aff id="Aff202">VingCard Elsafe, Moss, Norway</nlm:aff></affiliation></author><author><name sortKey="Maurer, M" sort="Maurer, M" uniqKey="Maurer M" first="M." last="Maurer">M. Maurer</name><affiliation><nlm:aff id="Aff203">Allergie-Centrum-Charité at the Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Berlin, Germany</nlm:aff></affiliation></author><author><name sortKey="Mavale Manuel, S" sort="Mavale Manuel, S" uniqKey="Mavale Manuel S" first="S." last="Mavale-Manuel">S. Mavale-Manuel</name><affiliation><nlm:aff id="Aff204">Department of Paediatrics, Maputo Central Hospital, Maputo, Mozambique</nlm:aff></affiliation></author><author><name sortKey="Melen, E" sort="Melen, E" uniqKey="Melen E" first="E." last="Melén">E. Melén</name><affiliation><nlm:aff id="Aff205">Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden</nlm:aff></affiliation></author><author><name sortKey="Melo Gomes, E" sort="Melo Gomes, E" uniqKey="Melo Gomes E" first="E." last="Melo-Gomes">E. Melo-Gomes</name><affiliation><nlm:aff id="Aff206">PNDR/Portuguese National Programme for Respiratory Diseases, Lisbon, Portugal</nlm:aff></affiliation></author><author><name sortKey="Meltzer, E O" sort="Meltzer, E O" uniqKey="Meltzer E" first="E. O." last="Meltzer">E. O. Meltzer</name><affiliation><nlm:aff id="Aff207">Allergy and Asthma Medical Group and Research Center, San Diego, CA USA</nlm:aff></affiliation></author><author><name sortKey="Menzies Gow, A" sort="Menzies Gow, A" uniqKey="Menzies Gow A" first="A." last="Menzies-Gow">A. Menzies-Gow</name><affiliation><nlm:aff id="Aff208">Royal Brompton Hospital, London, UK</nlm:aff></affiliation></author><author><name sortKey="Merk, H" sort="Merk, H" uniqKey="Merk H" first="H." last="Merk">H. Merk</name><affiliation><nlm:aff id="Aff209">Hautklinik - Klinik für Dermatologie & Allergologie, Universitätsklinikum der RWTH Aachen, Aachen, Germany</nlm:aff></affiliation></author><author><name sortKey="Michel, J P" sort="Michel, J P" uniqKey="Michel J" first="J. P." last="Michel">J. P. Michel</name><affiliation><nlm:aff id="Aff31">European Union GeriatricMedicine Society, EUGMS, Oslo, Norway</nlm:aff></affiliation></author><author><name sortKey="Miculinic, N" sort="Miculinic, N" uniqKey="Miculinic N" first="N." last="Miculinic">N. Miculinic</name><affiliation><nlm:aff id="Aff210">Croatian Pulmonary Society, Zagreb, Croatia</nlm:aff></affiliation></author><author><name sortKey="Mihaltan, F" sort="Mihaltan, F" uniqKey="Mihaltan F" first="F." last="Mihaltan">F. Mihaltan</name><affiliation><nlm:aff id="Aff211">National Institute of Pneumology M. Nasta, Bucharest, Romania</nlm:aff></affiliation></author><author><name sortKey="Milenkovic, B" sort="Milenkovic, B" uniqKey="Milenkovic B" first="B." last="Milenkovic">B. Milenkovic</name><affiliation><nlm:aff id="Aff212">Faculty of Medicine, University of Belgrade, Belgrade, Serbia</nlm:aff></affiliation><affiliation><nlm:aff id="Aff213">Serbian Association for Asthma and COPD, Belgrade, Serbia</nlm:aff></affiliation></author><author><name sortKey="Mohammad, G M Y" sort="Mohammad, G M Y" uniqKey="Mohammad G" first="G. M. Y." last="Mohammad">G. M. Y. Mohammad</name><affiliation><nlm:aff id="Aff214">National Center for Research in Chronic Respiratory Diseases, Tishreen University School of Medicine, Latakia, Syria</nlm:aff></affiliation></author><author><name sortKey="Molimard, M" sort="Molimard, M" uniqKey="Molimard M" first="M." last="Molimard">M. Molimard</name><affiliation><nlm:aff id="Aff215">Département de Pharmacologie, CHU de Bordeaux, Universite Bordeaux, INSERM U657, Bordeaux Cedex, France</nlm:aff></affiliation></author><author><name sortKey="Momas, I" sort="Momas, I" uniqKey="Momas I" first="I." last="Momas">I. Momas</name><affiliation><nlm:aff id="Aff216">Department of Public Health and Biostatistics, EA 4064, Paris Descartes University, Paris, France</nlm:aff></affiliation><affiliation><nlm:aff id="Aff217">Paris Municipal Department of Social Action, Childhood, and Health, Paris, France</nlm:aff></affiliation></author><author><name sortKey="Montilla Santana, A" sort="Montilla Santana, A" uniqKey="Montilla Santana A" first="A." last="Montilla-Santana">A. Montilla-Santana</name><affiliation><nlm:aff id="Aff218">Aura Andalucia, Andalucía, Spain</nlm:aff></affiliation></author><author><name sortKey="Morais Almeida, M" sort="Morais Almeida, M" uniqKey="Morais Almeida M" first="M." last="Morais-Almeida">M. Morais-Almeida</name><affiliation><nlm:aff id="Aff219">Allergy and Clinical Immunology Department, Hospital CUF-Descobertas, Lisbon, Portugal</nlm:aff></affiliation></author><author><name sortKey="Morgan, M" sort="Morgan, M" uniqKey="Morgan M" first="M." last="Morgan">M. Morgan</name><affiliation><nlm:aff id="Aff220">National Clinical Director for Respiratory Services, NHS England, Leeds, England, UK</nlm:aff></affiliation></author><author><name sortKey="Mosges, R" sort="Mosges, R" uniqKey="Mosges R" first="R." last="Mösges">R. Mösges</name><affiliation><nlm:aff id="Aff221">Institute of Medical Statistics, Informatics and Epidemiology, Medical Faculty, University of Cologne, Cologne, Germany</nlm:aff></affiliation></author><author><name sortKey="Mullol, J" sort="Mullol, J" uniqKey="Mullol J" first="J." last="Mullol">J. Mullol</name><affiliation><nlm:aff id="Aff178">Sachs’ Children’s Hospital, Stockholm, Sweden</nlm:aff></affiliation><affiliation><nlm:aff id="Aff179">Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden</nlm:aff></affiliation><affiliation><nlm:aff id="Aff222">Unitat de Rinologia i Clínica de l’Olfacte, Servei d’ORL, Hospital Clínic, Clinical and Experimental Respiratory Immunoallergy, IDIBAPS, Barcelona, Spain</nlm:aff></affiliation></author><author><name sortKey="Nafti, S" sort="Nafti, S" uniqKey="Nafti S" first="S." last="Nafti">S. Nafti</name><affiliation><nlm:aff id="Aff223">Mustapha Hospital, Algers, Algeria</nlm:aff></affiliation></author><author><name sortKey="Namazova Baranova, L" sort="Namazova Baranova, L" uniqKey="Namazova Baranova L" first="L." last="Namazova-Baranova">L. Namazova-Baranova</name><affiliation><nlm:aff id="Aff224">Scientific Centre of Children’s Health Under the Russian Academy of Medical Sciences, Moscow, Russia</nlm:aff></affiliation></author><author><name sortKey="Naclerio, R" sort="Naclerio, R" uniqKey="Naclerio R" first="R." last="Naclerio">R. Naclerio</name><affiliation><nlm:aff id="Aff225">Section of Otolaryngology-Head and Neck Surgery, The University of Chicago Medical Center and The Pritzker School of Medicine, The University of Chicago, Chicago, IL USA</nlm:aff></affiliation></author><author><name sortKey="Neou, A" sort="Neou, A" uniqKey="Neou A" first="A." last="Neou">A. Neou</name><affiliation><nlm:aff id="Aff36">Allergy-Centre-Charité at the Department of Dermatology, Charité - Universitätsmedizin Berlin, Berlin, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="Aff37">Secretary General of the Global Allergy and Asthma European Network (GA²LEN), Berlin, Germany</nlm:aff></affiliation></author><author><name sortKey="Neffen, H" sort="Neffen, H" uniqKey="Neffen H" first="H." last="Neffen">H. Neffen</name><affiliation><nlm:aff id="Aff226">Hospital de Niños Orlando Alassia, Santa Fe, Argentina</nlm:aff></affiliation></author><author><name sortKey="Nekam, K" sort="Nekam, K" uniqKey="Nekam K" first="K." last="Nekam">K. Nekam</name><affiliation><nlm:aff id="Aff227">Hospital of the Hospitaller Brothers in Buda, Budapest, Hungary</nlm:aff></affiliation></author><author><name sortKey="Niggemann, B" sort="Niggemann, B" uniqKey="Niggemann B" first="B." last="Niggemann">B. Niggemann</name><affiliation><nlm:aff id="Aff228">Pediatric Pneumology and Immunology, Charité Universitätsmedizin Berlin, Berlin, Germany</nlm:aff></affiliation></author><author><name sortKey="Ninot, G" sort="Ninot, G" uniqKey="Ninot G" first="G." last="Ninot">G. Ninot</name><affiliation><nlm:aff id="Aff229">EA4556 Epsylon, Université Montpellier 1, Montpellier, France</nlm:aff></affiliation></author><author><name sortKey="Nyembue, T D" sort="Nyembue, T D" uniqKey="Nyembue T" first="T. D." last="Nyembue">T. D. Nyembue</name><affiliation><nlm:aff id="Aff230">ENT Department, University Hospital of Kinshasa, Kinshasa, Congo</nlm:aff></affiliation></author><author><name sortKey="O Ehir, R E" sort="O Ehir, R E" uniqKey="O Ehir R" first="R. E." last="O Ehir">R. E. O Ehir</name><affiliation><nlm:aff id="Aff231">Department of Allergy, Immunology and Respiratory Medicine, Alfred Hospital and Central Clinical School, Monash University, Melbourne, VIC Australia</nlm:aff></affiliation><affiliation><nlm:aff id="Aff232">Department of Immunology, Monash University, Melbourne, VIC Australia</nlm:aff></affiliation></author><author><name sortKey="Ohta, K" sort="Ohta, K" uniqKey="Ohta K" first="K." last="Ohta">K. Ohta</name><affiliation><nlm:aff id="Aff233">National Hospital Organization, Tokyo National Hospital, Tokyo, Japan</nlm:aff></affiliation></author><author><name sortKey="Okamoto, Y" sort="Okamoto, Y" uniqKey="Okamoto Y" first="Y." last="Okamoto">Y. Okamoto</name><affiliation><nlm:aff id="Aff234">Department of Otorhinolaryngology, Chiba University Hospital, Chiba, Japan</nlm:aff></affiliation></author><author><name sortKey="Okubo, K" sort="Okubo, K" uniqKey="Okubo K" first="K." last="Okubo">K. Okubo</name><affiliation><nlm:aff id="Aff235">Department of Otolaryngology, Nippon Medical School, Tokyo, Japan</nlm:aff></affiliation></author><author><name sortKey="Ouedraogo, S" sort="Ouedraogo, S" uniqKey="Ouedraogo S" first="S." last="Ouedraogo">S. Ouedraogo</name><affiliation><nlm:aff id="Aff236">Centre Hospitalier Universitaire Pédiatrique Charles de Gaulle, Ouagadougou, Burkina Faso</nlm:aff></affiliation></author><author><name sortKey="Paggiaro, P" sort="Paggiaro, P" uniqKey="Paggiaro P" first="P." last="Paggiaro">P. Paggiaro</name><affiliation><nlm:aff id="Aff237">Cardio-Thoracic and Vascular Department, University Hospital of Pisa, Pisa, Italy</nlm:aff></affiliation></author><author><name sortKey="Pali Scholl, I" sort="Pali Scholl, I" uniqKey="Pali Scholl I" first="I." last="Pali-Schöll">I. Pali-Schöll</name><affiliation><nlm:aff id="Aff238">Department of Comparative Medicine, Messerli, Research Institute of the University of Veterinary Medicine and Medical University, Vienna, Austria</nlm:aff></affiliation></author><author><name sortKey="Panzner, P" sort="Panzner, P" uniqKey="Panzner P" first="P." last="Panzner">P. Panzner</name><affiliation><nlm:aff id="Aff239">Department of Immunology and Allergology, Faculty of Medicine and Faculty Hospital in Pilsen, Charles University in Prague, Pilsen, Czech Republic</nlm:aff></affiliation></author><author><name sortKey="Papadopoulos, N" sort="Papadopoulos, N" uniqKey="Papadopoulos N" first="N." last="Papadopoulos">N. Papadopoulos</name><affiliation><nlm:aff id="Aff240">Center for Pediatrics and Child Health, Institute of Human Development, Royal Manchester Children’s Hospital, University of Manchester, Manchester, M13 9WL UK</nlm:aff></affiliation><affiliation><nlm:aff id="Aff241">Allergy Department, 2nd Pediatric Clinic, Athens General Children’s Hospital “P&A Kyriakou”, University of Athens, Athens, 11527 Greece</nlm:aff></affiliation></author><author><name sortKey="Papi, A" sort="Papi, A" uniqKey="Papi A" first="A." last="Papi">A. Papi</name><affiliation><nlm:aff id="Aff242">Respiratory Medicine, Department of Medical Sciences, University of Ferrara, Ferrara, Italy</nlm:aff></affiliation></author><author><name sortKey="Park, H S" sort="Park, H S" uniqKey="Park H" first="H. S." last="Park">H. S. Park</name><affiliation><nlm:aff id="Aff243">Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, South Korea</nlm:aff></affiliation></author><author><name sortKey="Passalacqua, G" sort="Passalacqua, G" uniqKey="Passalacqua G" first="G." last="Passalacqua">G. Passalacqua</name><affiliation><nlm:aff id="Aff52">Allergy and Respiratory Diseases Clinic, DIMI, IRCCS AOU San Martino-IST, University of Genoa, Genoa, Italy</nlm:aff></affiliation></author><author><name sortKey="Pavord, I" sort="Pavord, I" uniqKey="Pavord I" first="I." last="Pavord">I. Pavord</name><affiliation><nlm:aff id="Aff244">Nuffield Department of Medicine, University of Oxford, Oxford, UK</nlm:aff></affiliation></author><author><name sortKey="Pawankar, R" sort="Pawankar, R" uniqKey="Pawankar R" first="R." last="Pawankar">R. Pawankar</name><affiliation><nlm:aff id="Aff245">Department of Pediatrics, Nippon Medical School, Tokyo, Japan</nlm:aff></affiliation></author><author><name sortKey="Pengelly, R" sort="Pengelly, R" uniqKey="Pengelly R" first="R." last="Pengelly">R. Pengelly</name><affiliation><nlm:aff id="Aff246">Department of Health, Social Services and Public Safety, Belfast, Northern Ireland, UK</nlm:aff></affiliation></author><author><name sortKey="Pfaar, O" sort="Pfaar, O" uniqKey="Pfaar O" first="O." last="Pfaar">O. Pfaar</name><affiliation><nlm:aff id="Aff247">Center for Rhinology and Allergology, Wiesbaden, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="Aff248">Department of Otorhinolaryngology, Head and Neck Surgery, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany</nlm:aff></affiliation></author><author><name sortKey="Picard, R" sort="Picard, R" uniqKey="Picard R" first="R." last="Picard">R. Picard</name><affiliation><nlm:aff id="Aff249">Conseil Général de l’Economie. Ministère de l’Economie, de l’Industrie et du Numérique, Paris, France</nlm:aff></affiliation></author><author><name sortKey="Pigearias, B" sort="Pigearias, B" uniqKey="Pigearias B" first="B." last="Pigearias">B. Pigearias</name><affiliation><nlm:aff id="Aff174">Société de Pneumologie de Langue Française, Espace francophone de Pneumologie, Paris, France</nlm:aff></affiliation></author><author><name sortKey="Pin, I" sort="Pin, I" uniqKey="Pin I" first="I." last="Pin">I. Pin</name><affiliation><nlm:aff id="Aff250">Département de pédiatrie, CHU de Grenoble, BP 217, 38043 Grenoble Cedex 9, France</nlm:aff></affiliation></author><author><name sortKey="Plavec, D" sort="Plavec, D" uniqKey="Plavec D" first="D." last="Plavec">D. Plavec</name><affiliation><nlm:aff id="Aff251">Children’s Hospital Srebrnjak, Zagreb, School of Medicine, University J.J. Strossmayer, Osijek, Croatia</nlm:aff></affiliation></author><author><name sortKey="Poethig, D" sort="Poethig, D" uniqKey="Poethig D" first="D." last="Poethig">D. Poethig</name><affiliation><nlm:aff id="Aff252">Im GerontoLab Europe - Europäische Vereinigung für Vitalität und Aktives Altern (eVAA) e.V., Leipzig, Germany</nlm:aff></affiliation></author><author><name sortKey="Pohl, W" sort="Pohl, W" uniqKey="Pohl W" first="W." last="Pohl">W. Pohl</name><affiliation><nlm:aff id="Aff253">Karl Landsteiner Institute for Clinical and Experimental Pneumology, Hietzing Hospital, Wolkersbergenstraße 1, 1130 Vienna, Austria</nlm:aff></affiliation></author><author><name sortKey="Popov, T A" sort="Popov, T A" uniqKey="Popov T" first="T. A." last="Popov">T. A. Popov</name><affiliation><nlm:aff id="Aff254">Clinic of Allergy and Asthma, Medical University Sofia, 1Sv. Georgi Sofiyski St., 1431 Sofia, Bulgaria</nlm:aff></affiliation></author><author><name sortKey="Portejoie, F" sort="Portejoie, F" uniqKey="Portejoie F" first="F." last="Portejoie">F. Portejoie</name><affiliation><nlm:aff id="Aff2">MACVIA-LR, Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc Roussilon, European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier, France</nlm:aff></affiliation></author><author><name sortKey="Potter, P" sort="Potter, P" uniqKey="Potter P" first="P." last="Potter">P. Potter</name><affiliation><nlm:aff id="Aff255">Allergy Diagnostic and Clinical Research Unit, University of Cape Town Lung Institute, Cape Town, South Africa</nlm:aff></affiliation></author><author><name sortKey="Postma, D" sort="Postma, D" uniqKey="Postma D" first="D." last="Postma">D. Postma</name><affiliation><nlm:aff id="Aff256">Department of Pulmonary Medicine and Tuberculosis, GRIAC Research Institute, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Price, D" sort="Price, D" uniqKey="Price D" first="D." last="Price">D. Price</name><affiliation><nlm:aff id="Aff257">Academic Centre of Primary Care, University of Aberdeen, Aberdeen, UK</nlm:aff></affiliation><affiliation><nlm:aff id="Aff258">Research in Real-Life, Cambridge, UK</nlm:aff></affiliation></author><author><name sortKey="Rabe, K F" sort="Rabe, K F" uniqKey="Rabe K" first="K. F." last="Rabe">K. F. Rabe</name><affiliation><nlm:aff id="Aff259">LungenClinic Grosshansdorf, Airway Research Center North, Member of the German Center for Lung Research (DZL), Grosshansdorf, Germany</nlm:aff></affiliation><affiliation><nlm:aff id="Aff260">Department of Medicine, Christian Albrechts University, Airway Research Center North, Member of the German Center for Lung Research (DZL), Kiel, Germany</nlm:aff></affiliation></author><author><name sortKey="Raciborski, F" sort="Raciborski, F" uniqKey="Raciborski F" first="F." last="Raciborski">F. Raciborski</name><affiliation><nlm:aff id="Aff28">Department of Prevention of Environmental Hazards and Allergology, Medical University of Warsaw, Warsaw, Poland</nlm:aff></affiliation></author><author><name sortKey="Radier Pontal, F" sort="Radier Pontal, F" uniqKey="Radier Pontal F" first="F." last="Radier Pontal">F. Radier Pontal</name><affiliation><nlm:aff id="Aff261">Conseil Départemental de l’Ordre des Pharmaciens, Maison des Professions Libérales, 34000 Montpellier, France</nlm:aff></affiliation></author><author><name sortKey="Repka Ramirez, S" sort="Repka Ramirez, S" uniqKey="Repka Ramirez S" first="S." last="Repka-Ramirez">S. Repka-Ramirez</name><affiliation><nlm:aff id="Aff262">SLAAI, Barranquilla, Colombia</nlm:aff></affiliation></author><author><name sortKey="Reitamo, S" sort="Reitamo, S" uniqKey="Reitamo S" first="S." last="Reitamo">S. Reitamo</name><affiliation><nlm:aff id="Aff19">Skin and Allergy Hospital, Helsinki University Hospital, Helsinki, Finland</nlm:aff></affiliation></author><author><name sortKey="Rennard, S" sort="Rennard, S" uniqKey="Rennard S" first="S." last="Rennard">S. Rennard</name><affiliation><nlm:aff id="Aff263">Division of Pulmonary, Critical Care, Sleep and Allergy, University of Nebraska Medical Center, Omaha, NE USA</nlm:aff></affiliation></author><author><name sortKey="Rodenas, F" sort="Rodenas, F" uniqKey="Rodenas F" first="F." last="Rodenas">F. Rodenas</name><affiliation><nlm:aff id="Aff135">Polibienestar Research Institute, University of Valencia, Valencia, Spain</nlm:aff></affiliation></author><author><name sortKey="Roberts, J" sort="Roberts, J" uniqKey="Roberts J" first="J." last="Roberts">J. Roberts</name><affiliation><nlm:aff id="Aff264">Salford, Royal NHS Foundation Trust and NHS England North, London, UK</nlm:aff></affiliation></author><author><name sortKey="Roca, J" sort="Roca, J" uniqKey="Roca J" first="J." last="Roca">J. Roca</name><affiliation><nlm:aff id="Aff40">Thorax Institute, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain</nlm:aff></affiliation></author><author><name sortKey="Rodriguez Ma As, L" sort="Rodriguez Ma As, L" uniqKey="Rodriguez Ma As L" first="L." last="Rodriguez Ma As">L. Rodriguez Ma As</name><affiliation><nlm:aff id="Aff265">Hospital Universitario de Getafe-Servicio Madrileño de Salud, Madrid, Spain</nlm:aff></affiliation></author><author><name sortKey="Rolland, C" sort="Rolland, C" uniqKey="Rolland C" first="C." last="Rolland">C. Rolland</name><affiliation><nlm:aff id="Aff266">Association Asthme et Allergie, Paris, France</nlm:aff></affiliation></author><author><name sortKey="Roman Rodriguez, M" sort="Roman Rodriguez, M" uniqKey="Roman Rodriguez M" first="M." last="Roman Rodriguez">M. Roman Rodriguez</name><affiliation><nlm:aff id="Aff267">Primary Care Respiratory Research Unit, Institutode Investigación Sanitaria de Palma IdisPa, Palma De Mallorca, Spain</nlm:aff></affiliation></author><author><name sortKey="Romano, A" sort="Romano, A" uniqKey="Romano A" first="A." last="Romano">A. Romano</name><affiliation><nlm:aff id="Aff268">Allergy Unit, Complesso integrato Columbus, Rome, Italy</nlm:aff></affiliation></author><author><name sortKey="Rosado Pinto, J" sort="Rosado Pinto, J" uniqKey="Rosado Pinto J" first="J." last="Rosado-Pinto">J. Rosado-Pinto</name><affiliation><nlm:aff id="Aff269">Serviço de Imunoalergologia, Hospital da Luz, Lisbon, Portugal</nlm:aff></affiliation></author><author><name sortKey="Rosario, N" sort="Rosario, N" uniqKey="Rosario N" first="N." last="Rosario">N. Rosario</name><affiliation><nlm:aff id="Aff270">Hospital de Clinicas, University of Parana, Curitiba, PR Brazil</nlm:aff></affiliation></author><author><name sortKey="Rosenwasser, L" sort="Rosenwasser, L" uniqKey="Rosenwasser L" first="L." last="Rosenwasser">L. Rosenwasser</name><affiliation><nlm:aff id="Aff271">Department of Allergy, Asthma, and Immunology, Children’s Mercy Hospitals and Clinics and Pediatrics, Medicine University of Misouri-Kansas City School of Medicine, Kansas City, MO USA</nlm:aff></affiliation></author><author><name sortKey="Rottem, M" sort="Rottem, M" uniqKey="Rottem M" first="M." last="Rottem">M. Rottem</name><affiliation><nlm:aff id="Aff272">Division of Allergy Asthma and Clinical Immunology, Emek Medical Center, Afula, Israel</nlm:aff></affiliation></author><author><name sortKey="Ryan, D" sort="Ryan, D" uniqKey="Ryan D" first="D." last="Ryan">D. Ryan</name><affiliation><nlm:aff id="Aff273">Woodbrook Medical Centre, Loughborough, UK</nlm:aff></affiliation><affiliation><nlm:aff id="Aff274">Honorary Clinical Research Fellow, Allergy and Respiratory Research Group, The University of Edinburgh, Edinburgh, UK</nlm:aff></affiliation></author><author><name sortKey="Sanchez Borges, M" sort="Sanchez Borges, M" uniqKey="Sanchez Borges M" first="M." last="Sanchez-Borges">M. Sanchez-Borges</name><affiliation><nlm:aff id="Aff275">Allergy and Clinical Immunology Department, Centro Médico-Docente la, Trinidad and Clínica El Avila, 6a transversal Urb, Altamira, piso 8, consultorio 803, Caracas, 1060 Venezuela</nlm:aff></affiliation></author><author><name sortKey="Scadding, G K" sort="Scadding, G K" uniqKey="Scadding G" first="G. K." last="Scadding">G. K. Scadding</name><affiliation><nlm:aff id="Aff276">The Royal National TNE Hospital, University College London, London, UK</nlm:aff></affiliation></author><author><name sortKey="Schunemann, H J" sort="Schunemann, H J" uniqKey="Schunemann H" first="H. J." last="Schunemann">H. J. Schunemann</name><affiliation><nlm:aff id="Aff76">Department of Clinical Epidemiology and Biostatistics, McMaster University, HSC Room 2C16, 1280 Main Street West Hamilton, Hamilton, Canada</nlm:aff></affiliation></author><author><name sortKey="Serrano, E" sort="Serrano, E" uniqKey="Serrano E" first="E." last="Serrano">E. Serrano</name><affiliation><nlm:aff id="Aff277">Otolaryngology and Head and Neck Surgery, CHU Rangueil-Larrey, Toulouse, France</nlm:aff></affiliation></author><author><name sortKey="Schmid Grendelmeier, P" sort="Schmid Grendelmeier, P" uniqKey="Schmid Grendelmeier P" first="P." last="Schmid-Grendelmeier">P. Schmid-Grendelmeier</name><affiliation><nlm:aff id="Aff278">Allergy Unit, Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland</nlm:aff></affiliation></author><author><name sortKey="Schulz, H" sort="Schulz, H" uniqKey="Schulz H" first="H." last="Schulz">H. Schulz</name><affiliation><nlm:aff id="Aff279">Helmholtz Zentrum München/Institute of Epidemiology I, Neuherberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Sheikh, A" sort="Sheikh, A" uniqKey="Sheikh A" first="A." last="Sheikh">A. Sheikh</name><affiliation><nlm:aff id="Aff280">Allergy and Respiratory Research Group, Centre for Population Health Sciences, Medical School, The University of Edinburgh, Edinburgh, UK</nlm:aff></affiliation></author><author><name sortKey="Shields, M" sort="Shields, M" uniqKey="Shields M" first="M." last="Shields">M. Shields</name><affiliation><nlm:aff id="Aff281">Child Health, Queen’s University Belfast and Royal Belfast Hospital for Sick Children, Belfast, UK</nlm:aff></affiliation></author><author><name sortKey="Siafakas, N" sort="Siafakas, N" uniqKey="Siafakas N" first="N." last="Siafakas">N. Siafakas</name><affiliation><nlm:aff id="Aff282">Department of Thoracic Medicine, University Hospital of Heraklion, Crete, Greece</nlm:aff></affiliation></author><author><name sortKey="Sibille, Y" sort="Sibille, Y" uniqKey="Sibille Y" first="Y." last="Sibille">Y. Sibille</name><affiliation><nlm:aff id="Aff283">University Hospital of Mont-Godinne, Catholic University of Louvain, Yvoir, Belgium</nlm:aff></affiliation></author><author><name sortKey="Similowski, T" sort="Similowski, T" uniqKey="Similowski T" first="T." last="Similowski">T. Similowski</name><affiliation><nlm:aff id="Aff284">Sorbonne Universités, UPMC Univ Paris 06, UMR_S 1158 Neurophysiologie Respiratoire Expérimentale et Clinique, Paris, France</nlm:aff></affiliation><affiliation><nlm:aff id="Aff285">INSERM, UMR_S 1158 Neurophysiologie Respiratoire Expérimentale et Clinique, Paris, France</nlm:aff></affiliation><affiliation><nlm:aff id="Aff286">Department R3S, AP-HP, Groupe, Paris, France</nlm:aff></affiliation></author><author><name sortKey="Simons, F E R" sort="Simons, F E R" uniqKey="Simons F" first="F. E. R." last="Simons">F. E. R. Simons</name><affiliation><nlm:aff id="Aff287">Department of Pediatrics and Child Health, Department of Immunology, Faculty of Medicine, University of Manitoba, Winnipeg, MB Canada</nlm:aff></affiliation></author><author><name sortKey="Sisul, J C" sort="Sisul, J C" uniqKey="Sisul J" first="J. C." last="Sisul">J. C. 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Zernotti</name><affiliation><nlm:aff id="Aff327">Universidad Católica de Córdoba, Córdoba, Argentina</nlm:aff></affiliation></author><author><name sortKey="Zhang, L" sort="Zhang, L" uniqKey="Zhang L" first="L." last="Zhang">L. Zhang</name><affiliation><nlm:aff id="Aff328">Department of Otolaryngology, Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730 China</nlm:aff></affiliation></author><author><name sortKey="Zhong, N" sort="Zhong, N" uniqKey="Zhong N" first="N." last="Zhong">N. Zhong</name><affiliation><nlm:aff id="Aff188">State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120 China</nlm:aff></affiliation></author><author><name sortKey="Zidarn, M" sort="Zidarn, M" uniqKey="Zidarn M" first="M." last="Zidarn">M. Zidarn</name><affiliation><nlm:aff id="Aff329">University Clinic of Respiratory and Allergic Diseases, Golnik, Slovenia</nlm:aff></affiliation></author><author><name sortKey="Mercier, J" sort="Mercier, J" uniqKey="Mercier J" first="J." last="Mercier">J. Mercier</name><affiliation><nlm:aff id="Aff330">Department of Physiology, CHRU and Vice President for Research, University Montpellier, Montpellier, France</nlm:aff></affiliation></author></analytic><series><title level="j">Clinical and Translational Allergy</title><idno type="eISSN">2045-7022</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) focuses on the integrated care of chronic diseases. Area 5 (Care Pathways) was initiated using chronic respiratory diseases as a model. The chronic respiratory disease action plan includes (1) AIRWAYS integrated care pathways (ICPs), (2) the joint initiative between the Reference site MACVIA-LR (<italic>Contre les MAladies Chroniques pour un VIeillissement Actif</italic>) and ARIA (Allergic Rhinitis and its Impact on Asthma), (3) Commitments for Action to the European Innovation Partnership on Active and Healthy Ageing and the AIRWAYS ICPs network. It is deployed in collaboration with the World Health Organization Global Alliance against Chronic Respiratory Diseases (GARD). The European Innovation Partnership on Active and Healthy Ageing has proposed a 5-step framework for developing an individual scaling up strategy: (1) what to scale up: (1-a) databases of good practices, (1-b) assessment of viability of the scaling up of good practices, (1-c) classification of good practices for local replication and (2) how to scale up: (2-a) facilitating partnerships for scaling up, (2-b) implementation of key success factors and lessons learnt, including emerging technologies for individualised and predictive medicine. This strategy has already been applied to the chronic respiratory disease action plan of the European Innovation Partnership on Active and Healthy Ageing.
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id="Aff1"><label>1</label>CHRU, University Hospital, 371 Avenue du Doyen Gaston Giraud, 34295 Montpellier Cedex 5, France</aff><aff id="Aff2"><label>2</label>MACVIA-LR, Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc Roussilon, European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier, France</aff><aff id="Aff3"><label>3</label>INSERM, VIMA: Ageing and Chronic Diseases, Epidemiological and Public Health Approaches, U1168, Paris, France</aff><aff id="Aff4"><label>4</label>UVSQ, UMR-S 1168, Université Versailles St-Quentin-en-Yvelines, Paris, France</aff><aff id="Aff5"><label>5</label>Department of Health, Social Services and Public Safety, Belfast, Northern Ireland, UK</aff><aff id="Aff6"><label>6</label>EIP on AHA, European Innovation Partnership on Active and Healthy Ageing, Reference Site, Scottish Centre for Telehealth and Telecare, NHS 24, Glasgow, UK</aff><aff id="Aff7"><label>7</label>Laboratory of Clinical Immunology, Department of Microbiology and Immunology, KU Leuven, Louvain, Belgium</aff><aff id="Aff8"><label>8</label>European Academy of Allergy and Clinical Immunology, Zurich, Switzerland</aff><aff id="Aff9"><label>9</label>Department of Respiratory Medicine, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, The Netherlands</aff><aff id="Aff10"><label>10</label>European Respiratory Society, Lausanne, Switzerland</aff><aff id="Aff11"><label>11</label>iQ4U Consultants Ltd, London, UK</aff><aff id="Aff12"><label>12</label>Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands</aff><aff id="Aff13"><label>13</label>Global Alliance Against Chronic Respiratory Diseases (GARD), Cape Town, South Africa</aff><aff id="Aff14"><label>14</label>International Primary Care Respiratory Group, Westhill, UK</aff><aff id="Aff15"><label>15</label>Life and Health Sciences Research Institute, ICVS, School of Health Sciences, University of Minho, Braga, Portugal</aff><aff id="Aff16"><label>16</label>ProAR – Nucleo de Excelencia em Asma, Federal University of Bahia, Bahia, Brazil</aff><aff id="Aff17"><label>17</label>GARD Executive Committee, Bahia, Brazil</aff><aff id="Aff18"><label>18</label>EIP on AHA Commitment for Action, Lisbon, Portugal</aff><aff id="Aff19"><label>19</label>Skin and Allergy Hospital, Helsinki University Hospital, Helsinki, Finland</aff><aff id="Aff20"><label>20</label>Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium</aff><aff id="Aff21"><label>21</label>Faculty of Medicine, University of Coimbra, Coimbra, Portugal</aff><aff id="Aff22"><label>22</label>Ageing@Coimbra Reference Site, Coimbra, Portugal</aff><aff id="Aff23"><label>23</label>Food Allergy Referral Centre Veneto Region, Department of Women and Child Health, Padua General University Hospital, Padua, Italy</aff><aff id="Aff24"><label>24</label>Caisse Assurance Retraite et Santé Au Travail Languedoc-Roussillon (CARSAT-LR), 34000 Montpellier, France</aff><aff id="Aff25"><label>25</label>EFA European Federation of Allergy and Airways Diseases Patients’ Associations, Brussels, Belgium</aff><aff id="Aff26"><label>26</label>University of Southern Denmark, Kolding, Denmark</aff><aff id="Aff27"><label>27</label>Centre of Pneumology, Coimbra University Hospital, Coimbra, Portugal</aff><aff id="Aff28"><label>28</label>Department of Prevention of Environmental Hazards and Allergology, Medical University of Warsaw, Warsaw, Poland</aff><aff id="Aff29"><label>29</label>Helsinki University, Helsinki University Hospital, Helsinki, Finland</aff><aff id="Aff30"><label>30</label>Center for Life Course Health Research, University of Oulu, Oulu, Finland</aff><aff id="Aff31"><label>31</label>European Union GeriatricMedicine Society, EUGMS, Oslo, Norway</aff><aff id="Aff32"><label>32</label>Center of Quality of Life Research, Vilnius University Clinic of Children’s Diseases, Vilnius University Public Health Institute, Vilnius, Lithuania</aff><aff id="Aff33"><label>33</label>European Association of Pediatrics (EAP/UEMS-SP), Brussels, Belgium</aff><aff id="Aff34"><label>34</label>Department of Pulmonology, Celal Bayar University, Manisa, Turkey</aff><aff id="Aff35"><label>35</label>Turkish Thoracic Society, Antalya, Turkey</aff><aff id="Aff36"><label>36</label>Allergy-Centre-Charité at the Department of Dermatology, Charité - Universitätsmedizin Berlin, Berlin, Germany</aff><aff id="Aff37"><label>37</label>Secretary General of the Global Allergy and Asthma European Network (GA²LEN), Berlin, Germany</aff><aff id="Aff38"><label>38</label>Department of Dermatology, Medical University of Graz, Graz, Austria</aff><aff id="Aff39"><label>39</label>Department of Clinical Research Center, International University of Health and Welfare/Sanno Hospital, Tokyo, Japan</aff><aff id="Aff40"><label>40</label>Thorax Institute, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain</aff><aff id="Aff41"><label>41</label>CIBER Enfermedades Respiratorias, Barcelona, Spain</aff><aff id="Aff42"><label>42</label>Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland</aff><aff id="Aff43"><label>43</label>EPAR U707 INSERM, Paris, France</aff><aff id="Aff44"><label>44</label>Department of Allergy and Immunology, Hospital Quirón Bizkaia, Erandio, Spain</aff><aff id="Aff45"><label>45</label>Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain</aff><aff id="Aff46"><label>46</label>Hospital del Mar Research Institute (IMIM), Barcelona, Spain</aff><aff id="Aff47"><label>47</label>CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain</aff><aff id="Aff48"><label>48</label>Department of Experimental and Health Sciences, University of Pompeu Fabra (UPF), Barcelona, Spain</aff><aff id="Aff49"><label>49</label>Digi Health, Montpellier, France</aff><aff id="Aff50"><label>50</label>David Hide Asthma and Allergy Research Centre, Isle of Wight, UK</aff><aff id="Aff51"><label>51</label>Shanghai Respiratory Research Institute, Vice President of Respiratory Society, Chinese Medical Association, China and Chinese Alliance Against Lung Cancer, Shanghai, China</aff><aff id="Aff52"><label>52</label>Allergy and Respiratory Diseases Clinic, DIMI, IRCCS AOU San Martino-IST, University of Genoa, Genoa, Italy</aff><aff id="Aff53"><label>53</label>Upper Airways Research Laboratory, ENT Department, Ghent University Hospital, Ghent, Belgium</aff><aff id="Aff54"><label>54</label>EuroAsian Respiratory Society, Astana City, Kazakhstan</aff><aff id="Aff55"><label>55</label>Faculdade de Medicina de Lisboa, Portuguese National Programme for Respiratory Diseases (PNDR), Lisbon, Portugal</aff><aff id="Aff56"><label>56</label>Department of Medicine, University of Cape Town, Cape Town, South Africa</aff><aff id="Aff57"><label>57</label>Section of Respiratory Disease, Department of Oncology, Haematology and Respiratory Diseases, University of Modena and Reggio Emilia, Modena, Italy</aff><aff id="Aff58"><label>58</label>Service de pneumologie IV, hôpital Abderrahman Mami, Ariana, 2080 Tunis, Tunisia</aff><aff id="Aff59"><label>59</label>Department of Respiratory Medicine, National Institute of Diseases of the Chest and Hospital, Dhaka, Bangladesh</aff><aff id="Aff60"><label>60</label>Centre for Individualized Medicine, Department of Pediatrics, Faculty of Medicine, LInköping University, Linköping, Sweden</aff><aff id="Aff61"><label>61</label>Department of Dermatology and Allergy, Rheinische Friedrich-Wilhelms-University Bonn, Bonn, Germany</aff><aff id="Aff62"><label>62</label>Department of Dermatology and Allergy Centre, Odense University Hospital, Odense, Denmark</aff><aff id="Aff63"><label>63</label>Department of Respiratory Medicine and Allergology, University Hospital, Lund, Sweden</aff><aff id="Aff64"><label>64</label>Department of Geriatrics, Montpellier University Hospital, Montpellier, France</aff><aff id="Aff65"><label>65</label>EA 2991, Euromov, University Montpellier, Montpellier, France</aff><aff id="Aff66"><label>66</label>Department of Pathophysiology and Transplantation, IRCCS Fondazione Ca’Granda Ospedale Maggiore Policlinico, University of Milan, Via F. Sforza 35, Milan, Italy</aff><aff id="Aff67"><label>67</label>Pediatric Department, University of Verona Hospital, Verona, Italy</aff><aff id="Aff68"><label>68</label>Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy</aff><aff id="Aff69"><label>69</label>Second University of Naples and Institute of Translational Medicine, Italian National Research Council, Naples, Italy</aff><aff id="Aff70"><label>70</label>Woolcock Institute of Medical Research, University of Sydney and Sydney Local Health District, Glebe, NSW Australia</aff><aff id="Aff71"><label>71</label>Quebec Heart and Lung Institute, Laval University, Québec City, QC Canada</aff><aff id="Aff72"><label>72</label>Directeur Général Adjoint, Montpellier University Hospital, Montpellier, France</aff><aff id="Aff73"><label>73</label>Health Economics and Health Technology Assessment, Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK</aff><aff id="Aff74"><label>74</label>Respiratory Biomedical Unit, Institute of Lung Health, University Hospitals of Leicester NHS Trust, Leicestershire, UK</aff><aff id="Aff75"><label>75</label>Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, UK</aff><aff id="Aff76"><label>76</label>Department of Clinical Epidemiology and Biostatistics, McMaster University, HSC Room 2C16, 1280 Main Street West Hamilton, Hamilton, Canada</aff><aff id="Aff77"><label>77</label>Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Mainz, Germany</aff><aff id="Aff78"><label>78</label>National Heart and Lung Institute, Imperial College, London, London, UK</aff><aff id="Aff79"><label>79</label>Wellcome Centre for Global Health, Imperial College, London, London, UK</aff><aff id="Aff80"><label>80</label>MRC-PHE Centre for Environment and Health, Imperial College, London, London, UK</aff><aff id="Aff81"><label>81</label>Imperial College and Royal Brompton Hospital, London, UK</aff><aff id="Aff82"><label>82</label>Centro Medico Docente La Trinidad, Caracas, Venezuela</aff><aff id="Aff83"><label>83</label>Department of Respiratory Diseases, Montpellier University Hospital, Montpellier, France</aff><aff id="Aff84"><label>84</label>National Heart and Lung Institute, Imperial College London, Royal Brompton Hospital NHS, London, UK</aff><aff id="Aff85"><label>85</label>Institute of Ageing and Chronic Disease, University of Liverpool and University Hospital Aintree, Liverpool, UK</aff><aff id="Aff86"><label>86</label>Department of Pediatrics, Medical School, Federal University of Minas Gerais, Belo Horizonte, Brazil</aff><aff id="Aff87"><label>87</label>Région Languedoc Roussillon, Montpellier, France</aff><aff id="Aff88"><label>88</label>Department of Paediatrics, Oslo University Hospital and University of Oslo, Oslo, Norway</aff><aff id="Aff89"><label>89</label>Allergy and Asthma Associates of Southern California, Mission Viejo, CA USA</aff><aff id="Aff90"><label>90</label>Regional Ministry of Equality, Health and Social Policies of Andalusia, Seville, Spain</aff><aff id="Aff91"><label>91</label>Division of Allergy/Immunology, University of South Florida, Tampa, FL USA</aff><aff id="Aff92"><label>92</label>Allergy and Immunology Laboratory, Metropolitan University, Simon Bolivar University, Barranquilla, Colombia</aff><aff id="Aff93"><label>93</label>Asma e Immunologia, SLaai, Sociedad Latinoamericana de Allergia, Barranquilla, Colombia</aff><aff id="Aff94"><label>94</label>Department of Social Medicine, Faculty of Medicine, University of Crete, PO Box 2208, Heraklion, 71003 Crete Greece</aff><aff id="Aff95"><label>95</label>National Cooperative Group of Paediatric Research on Asthma, Asthma Clinic and Education Center of the Capital Institute of Pediatrics, Peking and Center for Asthma Research and Education, Beijing, China</aff><aff id="Aff96"><label>96</label>Chachava Clinic, David Tvildiani Medical University-AIETI Medical School, Grigol Robakidze University, Tbilisi, Georgia</aff><aff id="Aff97"><label>97</label>Pulmonolory Research Institute FMBA, Moscow, Russia</aff><aff id="Aff98"><label>98</label>National Heart and Lung Institute, Imperial College, London, London, UK</aff><aff id="Aff99"><label>99</label>Medicine Department, IRCCS-Azienda Ospedaliera Universitaria San Martino, Genoa, Italy</aff><aff id="Aff100"><label>100</label>Latvian Allergy Association, Riga, Latvia</aff><aff id="Aff101"><label>101</label>Department of Medicine, Nova Southeastern University, Davie, FL USA</aff><aff id="Aff102"><label>102</label>Department of Paediatrics, Imperial College London, London, UK</aff><aff id="Aff103"><label>103</label>The Centre for Allergy Research, The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden</aff><aff id="Aff104"><label>104</label>Department of Dermatology and Allergy, Technische Universität München, Munich, Germany</aff><aff id="Aff105"><label>105</label>ZAUM-Center for Allergy and Environment, Helmholtz Center Munich, Technische Universität München, Munich, Germany</aff><aff id="Aff106"><label>106</label>Allergy Division, Chest Disease Department, University Hospital of Strasbourg, Strasbourg, France</aff><aff id="Aff107"><label>107</label>EUREGHA, European Regional and Local Health Association, Brussels, Belgium</aff><aff id="Aff108"><label>108</label>University of Edinburgh, Edinburgh, UK</aff><aff id="Aff109"><label>109</label>Allergology and Immunology Discipline, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania</aff><aff id="Aff110"><label>110</label>Kronikgune, Bilbao, Basque Region Spain</aff><aff id="Aff111"><label>111</label>Department of Medicine, Division of Clinical Immunology and Allergy, McMaster University, Hamilton, ON Canada</aff><aff id="Aff112"><label>112</label>Laboratoire de Pharmacologie Respiratoire UPRES EA220, Hôpital Foch, Suresnes Université Versailles Saint-Quentin, Suresnes, France</aff><aff id="Aff113"><label>113</label>Respiratory Diseases Department, Rangueil-Larrey Hospital, Toulouse, France</aff><aff id="Aff114"><label>114</label>Service de physiologie respiratoire, Hôpital Cochin, Université Paris-Descartes, Assistance publique-Hôpitaux de Paris, Paris, France</aff><aff id="Aff115"><label>115</label>NIHR Southampton Respiratory Biomedical Research Unit, Faculty of Medicine, University Southampton, Southampton, UK</aff><aff id="Aff116"><label>116</label>Medical Faculty Skopje, University Clinic of Pulmology and Allergy, Skopje, Republic Macedonia</aff><aff id="Aff117"><label>117</label>Service de Pneumo-Allergologie, Centre Hospitalo-Universitaire de Béni-Messous, Algers, Algeria</aff><aff id="Aff118"><label>118</label>Ecole des Mines, Alès, France</aff><aff id="Aff119"><label>119</label>Medical Faculty, Vilnius University, Vilnius, Lithuania</aff><aff id="Aff120"><label>120</label>Allergy and Clinical Immunology Section, National Heart and Lung Institute, Imperial College London, London, UK</aff><aff id="Aff121"><label>121</label>Section of Allergy and Immunology, Saint Louis University School of Medicine, Saint Louis, MO USA</aff><aff id="Aff122"><label>122</label>Pediatric Allergy and Immunology Unit, Ain Shams University, Cairo, Egypt</aff><aff id="Aff123"><label>123</label>Clinic of Children’s Diseases, Faculty of Medicine, Vilnius University, Vilnius, Lithuania</aff><aff id="Aff124"><label>124</label>Modena University, Modena, Italy</aff><aff id="Aff125"><label>125</label>Education for Health, Warwick, UK</aff><aff id="Aff126"><label>126</label>Division of Allergy, Department of Pediatric Medicine, The Bambino Gesù Children’s Research Hospital Holy See, Rome, Italy</aff><aff id="Aff127"><label>127</label>Global Allergy and Asthma Platform (GAAPP), Altgasse 8-10, 1130 Vienna, Austria</aff><aff id="Aff128"><label>128</label>Center for Health Technology and Services Research - CINTESIS, Faculdade de Medicina, Universidade do Porto, Porto, Portugal</aff><aff id="Aff129"><label>129</label>Allergy Unit, CUF Porto Instituto & Hospital, Porto, Portugal</aff><aff id="Aff130"><label>130</label>Department of Otorhinolaryngology, Academic Medical Centre, Amsterdam, The Netherlands</aff><aff id="Aff131"><label>131</label>Department of Epidemiology, Regional Health Service Lazio Region, Rome, Italy</aff><aff id="Aff132"><label>132</label>Repatriation General Hospital, Adelaide, SOUTH AUSTRALIA Australia</aff><aff id="Aff133"><label>133</label>Athens Chest Hospital, Athens, Greece</aff><aff id="Aff134"><label>134</label>National Center for Disease Control and Public Health of Georgia, Tbilisi, Georgia</aff><aff id="Aff135"><label>135</label>Polibienestar Research Institute, University of Valencia, Valencia, Spain</aff><aff id="Aff136"><label>136</label>Department of Pulmonary Diseases, Cerrahpasa Faculty of Medicine, Istanbul University, Istanbul, Turkey</aff><aff id="Aff137"><label>137</label>Allergy and Immunology Division, Clinica Ricardo Palma, Lima, Peru</aff><aff id="Aff138"><label>138</label>Universidad Autónoma de Nuevo León, San Nicolás De La Garza, Mexico</aff><aff id="Aff139"><label>139</label>Center of Allergy and Immunology, Georgian Association of Allergology and Clinical Immunology, Tbilisi, Georgia</aff><aff id="Aff140"><label>140</label>Latvian Association of Allergists, Center of Tuberculosis and Lung Diseases, Riga, Latvia</aff><aff id="Aff141"><label>141</label>Faculty of the Department of Neurology, University of Washington School of Medicine, St. Louis, MO USA</aff><aff id="Aff142"><label>142</label>University Hospital Olomouc – National eHealth Centre, Olomouc, Czech Republic</aff><aff id="Aff143"><label>143</label>Immunology and Allergy Division, Clinical Hospital, University of Chile, Santiago, Chile</aff><aff id="Aff144"><label>144</label>Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University Belfast, Belfast, UK</aff><aff id="Aff145"><label>145</label>Department of Respiratory Diseases, Odense University Hospital, Odense, Denmark</aff><aff id="Aff146"><label>146</label>NHS Scotland, Edinburgh, Scotland, UK</aff><aff id="Aff147"><label>147</label>Institute of Epidemiology I, German Research Centre for Environmental Health, Helmholtz Zentrum München, Neuherberg, Germany</aff><aff id="Aff148"><label>148</label>Agence Régionale de Santé, 34067 Montpellier Cedex 2, France</aff><aff id="Aff149"><label>149</label>Vienna Challenge Chamber, Vienna, Austria</aff><aff id="Aff150"><label>150</label>Department of Paediatrics and Child Health, University College Cork, Cork, Ireland</aff><aff id="Aff151"><label>151</label>University of Southampton Faculty of Medicine, University Hospital Southampton, Southampton, UK</aff><aff id="Aff152"><label>152</label>Service de Pneumologie, Hôpital Bicêtre, Inserm UMR_S999, Université Paris-Sud, Le Kremlin Bicêtre, France</aff><aff id="Aff153"><label>153</label>School of Psychology, Plymouth University, Plymouth, UK</aff><aff id="Aff154"><label>154</label>Federico II University Hospital/Campania RS, Naples, Italy</aff><aff id="Aff155"><label>155</label>Servicio de Alergia e Immunologia, Clinica Santa Isabel, Buenos Aires, Argentina</aff><aff id="Aff156"><label>156</label>Universidade Federal de Sao Paulo, São Paulo, Brazil</aff><aff id="Aff157"><label>157</label>Libra Foundation, Buenos Aires, Argentina</aff><aff id="Aff158"><label>158</label>The George Institute for Global Health, The University of Sydney, Camperdown, Australia</aff><aff id="Aff159"><label>159</label>Airway Disease Infection Section, National Heart and Lung Institute, Imperial College, London, London, UK</aff><aff id="Aff160"><label>160</label>MRC and Asthma UK Centre in Allergic Mechanisms of Asthma, London, UK</aff><aff id="Aff161"><label>161</label>Medical Commission, Montpellier University Hospital, Montpellier, France</aff><aff id="Aff162"><label>162</label>Children’s Clinic of Tartu University Hospital, Tartu, Estonia</aff><aff id="Aff163"><label>163</label>Hallym University College of Medicine, Hallym University Sacred Heart Hospital, Gyeonggi-Do, South Korea</aff><aff id="Aff164"><label>164</label>Allergology Department, Centre de l’Asthme et des Allergies, Hôpital d’Enfants Armand-Trousseau (APHP), Paris, France</aff><aff id="Aff165"><label>165</label>Sorbonne Universités, UPMC Univ Paris 06, UMR_S 1136, Institut Pierre Louis d’Epidémiologie et de Santé Publique, Equipe EPAR, 75013 Paris, France</aff><aff id="Aff166"><label>166</label>Ukrainian Medical Stomatological Academy, Poltava, Ukraine</aff><aff id="Aff167"><label>167</label>Federal Medicobiological Agency, Laboratory of Molecular Immunology, Institute of Immunology, National Research Center, Moscow, Russian Federation</aff><aff id="Aff168"><label>168</label>Pediatric Allergy and Asthma Unit, Hacettepe University School of Medicine, Ankara, Turkey</aff><aff id="Aff169"><label>169</label>Immunology and Allergy Division, Department of Chest Diseases, School of Medicine, Hacettepe University, Ankara, Turkey</aff><aff id="Aff170"><label>170</label>Institute of Social Medicine, Epidemiology and Health Economics, Charité - Universitätsmedizin Berlin, Berlin, Germany</aff><aff id="Aff171"><label>171</label>Institute for Clinical Epidemiology and Biometry, University of Würzburg, Würzburg, Germany</aff><aff id="Aff172"><label>172</label>Department of Medicine, McMaster University, Health Sciences Centre 3V47, 1280 Main Street West, Hamilton, Canada</aff><aff id="Aff173"><label>173</label>Center for Rhinology and Allergology, Wiesbaden, Germany</aff><aff id="Aff174"><label>174</label>Société de Pneumologie de Langue Française, Espace francophone de Pneumologie, Paris, France</aff><aff id="Aff175"><label>175</label>Department of Respiratory Medicine, Faculty of Medicine and Dentistry, University Hospital Olomouc, Olomouc, Czech Republic</aff><aff id="Aff176"><label>176</label>GRIACResearch Institute, Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children’s Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</aff><aff id="Aff177"><label>177</label>Department of Immunology, Rheumatology and Allergy, Medical University of Lodz, and HARC, Lodz, Poland</aff><aff id="Aff178"><label>178</label>Sachs’ Children’s Hospital, Stockholm, Sweden</aff><aff id="Aff179"><label>179</label>Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden</aff><aff id="Aff180"><label>180</label>Division of Internal Medicine, Asthma and Allergy, Barlicki University Hospital, Medical University of Lodz, Lodz, Poland</aff><aff id="Aff181"><label>181</label>Clinic of Infectious, Chest Diseases, Dermatology and Allergology, Vilnius University, Vilnius, Lithuania</aff><aff id="Aff182"><label>182</label>VIB Inflammation Research Center, Ghent University, Ghent, Belgium</aff><aff id="Aff183"><label>183</label>Department for Pediatric Pneumology and Immunology, Charité Medical University, Berlin, Germany</aff><aff id="Aff184"><label>184</label>Clínica de Alergia, Asma y Pediatría, Hospital Médica Sur, Ciudad De México, Mexico</aff><aff id="Aff185"><label>185</label>University of Medicine and Pharmacy, Hochiminh City, Vietnam</aff><aff id="Aff186"><label>186</label>Divisions of Allergy and Immunology, Departments of Internal Medicine and Pediatrics, University of Tennessee College of Medicine, Germantown, TN USA</aff><aff id="Aff187"><label>187</label>Scottish Centre for Respiratory Research, Cardiovascular and Diabetes Medicine, Medical Research Institute, Ninewells Hospital, University of Dundee, Dundee, UK</aff><aff id="Aff188"><label>188</label>State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120 China</aff><aff id="Aff189"><label>189</label>Department of Paediatrics, Oslo University Hospital, Oslo, Norway</aff><aff id="Aff190"><label>190</label>Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway</aff><aff id="Aff191"><label>191</label>Department of Pulmonary Medicine, CHU Sart-Tilman, Liege, Belgium</aff><aff id="Aff192"><label>192</label>Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, UK</aff><aff id="Aff193"><label>193</label>Service de Pneumo-allergologie, Hôpital Saint-Joseph, Paris, France</aff><aff id="Aff194"><label>194</label>Service de Pneumologie, UMR INSERM, UMR1087and CNR 6291, l’institut du thorax, University of Nantes, Nantes, France</aff><aff id="Aff195"><label>195</label>Department of Pulmonary Medicine, Rashid Hospital, Dubai, UAE</aff><aff id="Aff196"><label>196</label>Scottish Government Health Department, eHealth and Pharmaceuticals, Edinburgh, UK</aff><aff id="Aff197"><label>197</label>Department of Respiratory Medicine, University of Bratislava, Bratislava, Slovakia</aff><aff id="Aff198"><label>198</label>Department of Medicine (RCSI), Bon Secours Hospital, Glasnevin, Dublin, Ireland</aff><aff id="Aff199"><label>199</label>Cardiovascular and Thoracic Department, AOU Città della Salute e della Scienza di Torino, Turin, Italy</aff><aff id="Aff200"><label>200</label>Division of Clinical Immunology and Allergy, Laboratory of Behavioral Immunology Research, The University of Mississippi Medical Center, Jackson, MS USA</aff><aff id="Aff201"><label>201</label>Respiratory Medicine Research, Shahid Beheshti University of Medical Sciences, Tehran, Iran</aff><aff id="Aff202"><label>202</label>VingCard Elsafe, Moss, Norway</aff><aff id="Aff203"><label>203</label>Allergie-Centrum-Charité at the Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Berlin, Germany</aff><aff id="Aff204"><label>204</label>Department of Paediatrics, Maputo Central Hospital, Maputo, Mozambique</aff><aff id="Aff205"><label>205</label>Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden</aff><aff id="Aff206"><label>206</label>PNDR/Portuguese National Programme for Respiratory Diseases, Lisbon, Portugal</aff><aff id="Aff207"><label>207</label>Allergy and Asthma Medical Group and Research Center, San Diego, CA USA</aff><aff id="Aff208"><label>208</label>Royal Brompton Hospital, London, UK</aff><aff id="Aff209"><label>209</label>Hautklinik - Klinik für Dermatologie & Allergologie, Universitätsklinikum der RWTH Aachen, Aachen, Germany</aff><aff id="Aff210"><label>210</label>Croatian Pulmonary Society, Zagreb, Croatia</aff><aff id="Aff211"><label>211</label>National Institute of Pneumology M. Nasta, Bucharest, Romania</aff><aff id="Aff212"><label>212</label>Faculty of Medicine, University of Belgrade, Belgrade, Serbia</aff><aff id="Aff213"><label>213</label>Serbian Association for Asthma and COPD, Belgrade, Serbia</aff><aff id="Aff214"><label>214</label>National Center for Research in Chronic Respiratory Diseases, Tishreen University School of Medicine, Latakia, Syria</aff><aff id="Aff215"><label>215</label>Département de Pharmacologie, CHU de Bordeaux, Universite Bordeaux, INSERM U657, Bordeaux Cedex, France</aff><aff id="Aff216"><label>216</label>Department of Public Health and Biostatistics, EA 4064, Paris Descartes University, Paris, France</aff><aff id="Aff217"><label>217</label>Paris Municipal Department of Social Action, Childhood, and Health, Paris, France</aff><aff id="Aff218"><label>218</label>Aura Andalucia, Andalucía, Spain</aff><aff id="Aff219"><label>219</label>Allergy and Clinical Immunology Department, Hospital CUF-Descobertas, Lisbon, Portugal</aff><aff id="Aff220"><label>220</label>National Clinical Director for Respiratory Services, NHS England, Leeds, England, UK</aff><aff id="Aff221"><label>221</label>Institute of Medical Statistics, Informatics and Epidemiology, Medical Faculty, University of Cologne, Cologne, Germany</aff><aff id="Aff222"><label>222</label>Unitat de Rinologia i Clínica de l’Olfacte, Servei d’ORL, Hospital Clínic, Clinical and Experimental Respiratory Immunoallergy, IDIBAPS, Barcelona, Spain</aff><aff id="Aff223"><label>223</label>Mustapha Hospital, Algers, Algeria</aff><aff id="Aff224"><label>224</label>Scientific Centre of Children’s Health Under the Russian Academy of Medical Sciences, Moscow, Russia</aff><aff id="Aff225"><label>225</label>Section of Otolaryngology-Head and Neck Surgery, The University of Chicago Medical Center and The Pritzker School of Medicine, The University of Chicago, Chicago, IL USA</aff><aff id="Aff226"><label>226</label>Hospital de Niños Orlando Alassia, Santa Fe, Argentina</aff><aff id="Aff227"><label>227</label>Hospital of the Hospitaller Brothers in Buda, Budapest, Hungary</aff><aff id="Aff228"><label>228</label>Pediatric Pneumology and Immunology, Charité Universitätsmedizin Berlin, Berlin, Germany</aff><aff id="Aff229"><label>229</label>EA4556 Epsylon, Université Montpellier 1, Montpellier, France</aff><aff id="Aff230"><label>230</label>ENT Department, University Hospital of Kinshasa, Kinshasa, Congo</aff><aff id="Aff231"><label>231</label>Department of Allergy, Immunology and Respiratory Medicine, Alfred Hospital and Central Clinical School, Monash University, Melbourne, VIC Australia</aff><aff id="Aff232"><label>232</label>Department of Immunology, Monash University, Melbourne, VIC Australia</aff><aff id="Aff233"><label>233</label>National Hospital Organization, Tokyo National Hospital, Tokyo, Japan</aff><aff id="Aff234"><label>234</label>Department of Otorhinolaryngology, Chiba University Hospital, Chiba, Japan</aff><aff id="Aff235"><label>235</label>Department of Otolaryngology, Nippon Medical School, Tokyo, Japan</aff><aff id="Aff236"><label>236</label>Centre Hospitalier Universitaire Pédiatrique Charles de Gaulle, Ouagadougou, Burkina Faso</aff><aff id="Aff237"><label>237</label>Cardio-Thoracic and Vascular Department, University Hospital of Pisa, Pisa, Italy</aff><aff id="Aff238"><label>238</label>Department of Comparative Medicine, Messerli, Research Institute of the University of Veterinary Medicine and Medical University, Vienna, Austria</aff><aff id="Aff239"><label>239</label>Department of Immunology and Allergology, Faculty of Medicine and Faculty Hospital in Pilsen, Charles University in Prague, Pilsen, Czech Republic</aff><aff id="Aff240"><label>240</label>Center for Pediatrics and Child Health, Institute of Human Development, Royal Manchester Children’s Hospital, University of Manchester, Manchester, M13 9WL UK</aff><aff id="Aff241"><label>241</label>Allergy Department, 2nd Pediatric Clinic, Athens General Children’s Hospital “P&A Kyriakou”, University of Athens, Athens, 11527 Greece</aff><aff id="Aff242"><label>242</label>Respiratory Medicine, Department of Medical Sciences, University of Ferrara, Ferrara, Italy</aff><aff id="Aff243"><label>243</label>Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, South Korea</aff><aff id="Aff244"><label>244</label>Nuffield Department of Medicine, University of Oxford, Oxford, UK</aff><aff id="Aff245"><label>245</label>Department of Pediatrics, Nippon Medical School, Tokyo, Japan</aff><aff id="Aff246"><label>246</label>Department of Health, Social Services and Public Safety, Belfast, Northern Ireland, UK</aff><aff id="Aff247"><label>247</label>Center for Rhinology and Allergology, Wiesbaden, Germany</aff><aff id="Aff248"><label>248</label>Department of Otorhinolaryngology, Head and Neck Surgery, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany</aff><aff id="Aff249"><label>249</label>Conseil Général de l’Economie. Ministère de l’Economie, de l’Industrie et du Numérique, Paris, France</aff><aff id="Aff250"><label>250</label>Département de pédiatrie, CHU de Grenoble, BP 217, 38043 Grenoble Cedex 9, France</aff><aff id="Aff251"><label>251</label>Children’s Hospital Srebrnjak, Zagreb, School of Medicine, University J.J. Strossmayer, Osijek, Croatia</aff><aff id="Aff252"><label>252</label>Im GerontoLab Europe - Europäische Vereinigung für Vitalität und Aktives Altern (eVAA) e.V., Leipzig, Germany</aff><aff id="Aff253"><label>253</label>Karl Landsteiner Institute for Clinical and Experimental Pneumology, Hietzing Hospital, Wolkersbergenstraße 1, 1130 Vienna, Austria</aff><aff id="Aff254"><label>254</label>Clinic of Allergy and Asthma, Medical University Sofia, 1Sv. Georgi Sofiyski St., 1431 Sofia, Bulgaria</aff><aff id="Aff255"><label>255</label>Allergy Diagnostic and Clinical Research Unit, University of Cape Town Lung Institute, Cape Town, South Africa</aff><aff id="Aff256"><label>256</label>Department of Pulmonary Medicine and Tuberculosis, GRIAC Research Institute, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</aff><aff id="Aff257"><label>257</label>Academic Centre of Primary Care, University of Aberdeen, Aberdeen, UK</aff><aff id="Aff258"><label>258</label>Research in Real-Life, Cambridge, UK</aff><aff id="Aff259"><label>259</label>LungenClinic Grosshansdorf, Airway Research Center North, Member of the German Center for Lung Research (DZL), Grosshansdorf, Germany</aff><aff id="Aff260"><label>260</label>Department of Medicine, Christian Albrechts University, Airway Research Center North, Member of the German Center for Lung Research (DZL), Kiel, Germany</aff><aff id="Aff261"><label>261</label>Conseil Départemental de l’Ordre des Pharmaciens, Maison des Professions Libérales, 34000 Montpellier, France</aff><aff id="Aff262"><label>262</label>SLAAI, Barranquilla, Colombia</aff><aff id="Aff263"><label>263</label>Division of Pulmonary, Critical Care, Sleep and Allergy, University of Nebraska Medical Center, Omaha, NE USA</aff><aff id="Aff264"><label>264</label>Salford, Royal NHS Foundation Trust and NHS England North, London, UK</aff><aff id="Aff265"><label>265</label>Hospital Universitario de Getafe-Servicio Madrileño de Salud, Madrid, Spain</aff><aff id="Aff266"><label>266</label>Association Asthme et Allergie, Paris, France</aff><aff id="Aff267"><label>267</label>Primary Care Respiratory Research Unit, Institutode Investigación Sanitaria de Palma IdisPa, Palma De Mallorca, Spain</aff><aff id="Aff268"><label>268</label>Allergy Unit, Complesso integrato Columbus, Rome, Italy</aff><aff id="Aff269"><label>269</label>Serviço de Imunoalergologia, Hospital da Luz, Lisbon, Portugal</aff><aff id="Aff270"><label>270</label>Hospital de Clinicas, University of Parana, Curitiba, PR Brazil</aff><aff id="Aff271"><label>271</label>Department of Allergy, Asthma, and Immunology, Children’s Mercy Hospitals and Clinics and Pediatrics, Medicine University of Misouri-Kansas City School of Medicine, Kansas City, MO USA</aff><aff id="Aff272"><label>272</label>Division of Allergy Asthma and Clinical Immunology, Emek Medical Center, Afula, Israel</aff><aff id="Aff273"><label>273</label>Woodbrook Medical Centre, Loughborough, UK</aff><aff id="Aff274"><label>274</label>Honorary Clinical Research Fellow, Allergy and Respiratory Research Group, The University of Edinburgh, Edinburgh, UK</aff><aff id="Aff275"><label>275</label>Allergy and Clinical Immunology Department, Centro Médico-Docente la, Trinidad and Clínica El Avila, 6a transversal Urb, Altamira, piso 8, consultorio 803, Caracas, 1060 Venezuela</aff><aff id="Aff276"><label>276</label>The Royal National TNE Hospital, University College London, London, UK</aff><aff id="Aff277"><label>277</label>Otolaryngology and Head and Neck Surgery, CHU Rangueil-Larrey, Toulouse, France</aff><aff id="Aff278"><label>278</label>Allergy Unit, Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland</aff><aff id="Aff279"><label>279</label>Helmholtz Zentrum München/Institute of Epidemiology I, Neuherberg, Germany</aff><aff id="Aff280"><label>280</label>Allergy and Respiratory Research Group, Centre for Population Health Sciences, Medical School, The University of Edinburgh, Edinburgh, UK</aff><aff id="Aff281"><label>281</label>Child Health, Queen’s University Belfast and Royal Belfast Hospital for Sick Children, Belfast, UK</aff><aff id="Aff282"><label>282</label>Department of Thoracic Medicine, University Hospital of Heraklion, Crete, Greece</aff><aff id="Aff283"><label>283</label>University Hospital of Mont-Godinne, Catholic University of Louvain, Yvoir, Belgium</aff><aff id="Aff284"><label>284</label>Sorbonne Universités, UPMC Univ Paris 06, UMR_S 1158 Neurophysiologie Respiratoire Expérimentale et Clinique, Paris, France</aff><aff id="Aff285"><label>285</label>INSERM, UMR_S 1158 Neurophysiologie Respiratoire Expérimentale et Clinique, Paris, France</aff><aff id="Aff286"><label>286</label>Department R3S, AP-HP, Groupe, Paris, France</aff><aff id="Aff287"><label>287</label>Department of Pediatrics and Child Health, Department of Immunology, Faculty of Medicine, University of Manitoba, Winnipeg, MB Canada</aff><aff id="Aff288"><label>288</label>Sociedad Paraguaya de Alergia Asma e Inmunología, Asunción, Paraguay</aff><aff id="Aff289"><label>289</label>Julius Center of Health Sciences and Primary Care, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands</aff><aff id="Aff290"><label>290</label>Division of Allergy, Clinical Immunology and Rheumatology, Department of Pediatrics, Federal University of São Paulo, São Paulo, Brazil</aff><aff id="Aff291"><label>291</label>Kyrgyzstan National Centre of Cardiology and Internal Medicine, Euro-Asian Respiratory Society, Bishkek, Kyrgyzstan</aff><aff id="Aff292"><label>292</label>Pulmonary Division, Heart Institute (InCor), Hospital da Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Brazil</aff><aff id="Aff293"><label>293</label>Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands</aff><aff id="Aff294"><label>294</label>Department of Epidemiology, CAPHRI School of Public Health and Primary Care, Maastricht University, Maastricht, The Netherlands</aff><aff id="Aff295"><label>295</label>Sidkkids hospitala and Institute of Health Policy, Management and Evaluation, Toronto, ON Canada</aff><aff id="Aff296"><label>296</label>Centre of Pneumology, Faculty of Medicine, University of Coimbra, Coimbra, Portugal</aff><aff id="Aff297"><label>297</label>Division of Allergy and Clinical Immunology, University of Salerno, Salerno, Italy</aff><aff id="Aff298"><label>298</label>Division of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria</aff><aff id="Aff299"><label>299</label>Pneumology and Allergy Department, Hospital Clínic, Clinical and Experimental Respiratory Immunoallergy, IDIBAPS, Barcelona, Spain</aff><aff id="Aff300"><label>300</label>Department of Lung Diseases and Clinical Allergology, University of Turku, Turku, Finland</aff><aff id="Aff301"><label>301</label>Unité de Pharmacoépidémiologie, CHU-Lyon - UR 5558 CNRS, Université Claude Bernard, Lyon, Villeurbanne, France</aff><aff id="Aff302"><label>302</label>Clinical Immunology and Allergy Unit, Department of Medicine Solna, Karolinska Institutet and University Hospital, Stockholm, Sweden</aff><aff id="Aff303"><label>303</label>Department of Chest Medicine, Centre Hospitalier Universitaire Dinant-Godinne, Université Catholique de Louvain, Yvoir, Belgium</aff><aff id="Aff304"><label>304</label>FILHA, Finnish Lung Association, Helsinki, Finland</aff><aff id="Aff305"><label>305</label>Gérontopôle, CHU Toulouse, Toulouse, France</aff><aff id="Aff306"><label>306</label>Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK</aff><aff id="Aff307"><label>307</label>University Hospital of South Manchester, Manchester NHS Foundation Trust, Manchester, UK</aff><aff id="Aff308"><label>308</label>Pulmonary Unit, Department of Cardiology, Thoracic and Vascular Medicine, Arcispedale S.Maria Nuova/IRCCS, Research Hospital, Reggio Emilia, Italy</aff><aff id="Aff309"><label>309</label>Regional Agency for Health and Social Care, Reggio Emilia, Italy</aff><aff id="Aff310"><label>310</label>Division of Allergy and Immunology, Department of Pediatrics, Siriraj Hospital, Mahidol University Faculty of Medicine, Bangkok, 10700 Thailand</aff><aff id="Aff311"><label>311</label>Pulmonary Environmental Epidemiology Unit, CNR Institute of Clinical Physiology, Pisa, Via Trieste 41, 56126 Pisa, Italy</aff><aff id="Aff312"><label>312</label>CNR Institute of Biomedicine and Molecular Immunology “A. Monroy”, Via U. La Malfa 153, 90146 Palermo, Italy</aff><aff id="Aff313"><label>313</label>Department of Medicine, Pulmonary and Critical Care Medicine, University Medical Center Giessen and Marburg, Philipps-University Marburg, Marburg, Germany</aff><aff id="Aff314"><label>314</label>Sotiria Hospital, Athens, Greece</aff><aff id="Aff315"><label>315</label>Department of Otorhinolaryngology, HNO-Klinik, Universitätsklinikum Düsseldorf, Düsseldorf, Germany</aff><aff id="Aff316"><label>316</label>Hôpital Albert Calmette, CHRU, Lille, France</aff><aff id="Aff317"><label>317</label>Asthma UK, Mansell Street, London, UK</aff><aff id="Aff318"><label>318</label>Department of Otolaryngology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore</aff><aff id="Aff319"><label>319</label>Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC USA</aff><aff id="Aff320"><label>320</label>Bradford Institute for Health Research, Bradford Royal Infirmary, Bradford, UK</aff><aff id="Aff321"><label>321</label>Department of Research, Olmsted Medical Center, Rochester, MN USA</aff><aff id="Aff322"><label>322</label>Cyprus International Institute for Environmental and Public Health in Association with Harvard School of Public Health, Cyprus University of Technology, Limassol, Cyprus</aff><aff id="Aff323"><label>323</label>Department of Pediatrics, Hospital “Archbishop Makarios III”, Nicosia, Cyprus</aff><aff id="Aff324"><label>324</label>The Allergy and Asthma Institute, Lahore, Pakistan</aff><aff id="Aff325"><label>325</label>Social Sciences, University of Southampton, Southampton, UK</aff><aff id="Aff326"><label>326</label>Department of Paediatrics and Child Health, Red Cross Children’s Hospital, and MRC Unit on Child and Adolescent Health, University of Cape Town, Cape Town, South Africa</aff><aff id="Aff327"><label>327</label>Universidad Católica de Córdoba, Córdoba, Argentina</aff><aff id="Aff328"><label>328</label>Department of Otolaryngology, Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730 China</aff><aff id="Aff329"><label>329</label>University Clinic of Respiratory and Allergic Diseases, Golnik, Slovenia</aff><aff id="Aff330"><label>330</label>Department of Physiology, CHRU and Vice President for Research, University Montpellier, Montpellier, France</aff><aff id="Aff331"><label>331</label>EPAR UMR-S UPMC, Paris VI, Paris, France</aff></contrib-group><pub-date pub-type="epub"><day>29</day><month>7</month><year>2016</year></pub-date><pub-date pub-type="pmc-release"><day>29</day><month>7</month><year>2016</year></pub-date><pub-date pub-type="collection"><year>2016</year></pub-date><volume>6</volume><elocation-id>29</elocation-id><history><date date-type="received"><day>14</day><month>4</month><year>2016</year></date><date date-type="accepted"><day>2</day><month>6</month><year>2016</year></date></history><permissions><copyright-statement>© The Author(s) 2016</copyright-statement><license license-type="OpenAccess"><license-p><bold>Open Access</bold>This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/4.0/">http://creativecommons.org/licenses/by/4.0/</ext-link>), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/publicdomain/zero/1.0/">http://creativecommons.org/publicdomain/zero/1.0/</ext-link>) applies to the data made available in this article, unless otherwise stated.</license-p></license></permissions><abstract id="Abs1"><p>Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) focuses on the integrated care of chronic diseases. Area 5 (Care Pathways) was initiated using chronic respiratory diseases as a model. The chronic respiratory disease action plan includes (1) AIRWAYS integrated care pathways (ICPs), (2) the joint initiative between the Reference site MACVIA-LR (<italic>Contre les MAladies Chroniques pour un VIeillissement Actif</italic>) and ARIA (Allergic Rhinitis and its Impact on Asthma), (3) Commitments for Action to the European Innovation Partnership on Active and Healthy Ageing and the AIRWAYS ICPs network. It is deployed in collaboration with the World Health Organization Global Alliance against Chronic Respiratory Diseases (GARD). The European Innovation Partnership on Active and Healthy Ageing has proposed a 5-step framework for developing an individual scaling up strategy: (1) what to scale up: (1-a) databases of good practices, (1-b) assessment of viability of the scaling up of good practices, (1-c) classification of good practices for local replication and (2) how to scale up: (2-a) facilitating partnerships for scaling up, (2-b) implementation of key success factors and lessons learnt, including emerging technologies for individualised and predictive medicine. This strategy has already been applied to the chronic respiratory disease action plan of the European Innovation Partnership on Active and Healthy Ageing.
</p><sec><title>Electronic supplementary material</title><p>The online version of this article (doi:10.1186/s13601-016-0116-9) contains supplementary material, which is available to authorized users.</p></sec></abstract><kwd-group xml:lang="en"><title>Keywords</title><kwd>EIP on AHA</kwd><kwd>European Innovation Partnership on Active and Healthy Ageing</kwd><kwd>Chronic respiratory diseases</kwd><kwd>AIRWAYS ICPs</kwd><kwd>MACVIA</kwd><kwd>ARIA</kwd><kwd>Scaling up</kwd></kwd-group><custom-meta-group><custom-meta><meta-name>issue-copyright-statement</meta-name><meta-value>© The Author(s) 2016</meta-value></custom-meta></custom-meta-group></article-meta></front><body><sec id="Sec1" sec-type="introduction"><title>Background</title><p>Health and care services in Europe are undergoing changes to adapt systems to the growing demands caused by the expansion of chronic diseases and ageing. This restructuring involves the development and testing of innovative solutions as well as the implementation of the most successful pilots. The multitude of good practices developed throughout the European Union favours a comprehensive and multi-dimensional scaling-up strategy at European level [<xref ref-type="bibr" rid="CR1">1</xref>].</p><p>The European Commission DG Santé (Directorate General for Health and Food Safety) and DG CNECT (Directorate General for Communications Networks, Content and Technology) launched the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) to enhance European Union competitiveness and to tackle societal challenges through research and innovation (Table <xref rid="Tab1" ref-type="table">1</xref>) [<xref ref-type="bibr" rid="CR2">2</xref>].<table-wrap id="Tab1"><label>Table 1</label><caption><p>Priority areas and action plans of the EIP on AHA</p></caption><table frame="hsides" rules="groups"><thead><tr><th align="left">Priority areas</th><th align="left">Action plans</th></tr></thead><tbody><tr><td align="left">Prevention of diseases and health promotion</td><td align="left"></td></tr><tr><td align="left"> A1</td><td align="left">Innovative ways to ensure that patients adhere to their treatment</td></tr><tr><td align="left"> A2</td><td align="left">Innovative solutions for personalised health management, with focus on falls prevention</td></tr><tr><td align="left"> A3</td><td align="left">Action for preventing functional decline and frailty, with a particular focus on malnutrition</td></tr><tr><td align="left">Care and cure</td><td align="left"></td></tr><tr><td align="left"> B3</td><td align="left">Scaling up and replication of successful innovative integrated care models for CD amongst older patients, such as through remote monitoring</td></tr><tr><td align="left">Active and independent living of older adults</td><td align="left"></td></tr><tr><td align="left"> C2</td><td align="left">Improving the uptake of interoperable independent living solutions including guidelines for business models</td></tr><tr><td align="left">Horizontal topics</td><td align="left"></td></tr><tr><td align="left"> D4</td><td align="left">Networking and knowledge sharing on innovation for age-friendly environments</td></tr></tbody></table></table-wrap></p><p>Chronic respiratory diseases are the pilot for chronic diseases of the EIP on AHA Action Plan B3 [<xref ref-type="bibr" rid="CR3">3</xref>, <xref ref-type="bibr" rid="CR4">4</xref>]. Several effective plans exist in Europe for chronic respiratory diseases, but they are rarely deployed to other regions or countries. There is an urgent need for scaling up strategies in order to (1) avoid fragmentation, (2) improve health care delivery across Europe, (3) speed up the implementation of good practices using existing cost-effective success stories and (4) meet the triple win of the EIP on AHA:<list list-type="bullet"><list-item><p>Enabling European citizens to lead healthy, active and independent lives while ageing.</p></list-item><list-item><p>Improving the sustainability and efficiency of social and health care systems.</p></list-item><list-item><p>Boosting and improving the competitiveness of the markets for innovative products and services, responding to the ageing challenge and creating new opportunities for businesses.</p></list-item></list></p><p>This paper presents the scaling up strategy for chronic respiratory diseases strictly following the five-step framework scaling up strategy of the EIP on AHA. It may be used as a model for scaling up activities in other areas of the EIP on AHA and other chronic diseases.</p></sec><sec id="Sec2"><title>AIRWAYS ICPs, the pilot for chronic diseases of the EIP on AHA</title><p>Chronic respiratory diseases include a variety of diseases such as airway diseases (allergic and non-allergic asthma, rhinitis, rhinosinusitis and COPD), occupational lung diseases, sleep apnoea syndrome, interstitial diseases, pulmonary vascular diseases and genetic diseases such as cystic fibrosis [<xref ref-type="bibr" rid="CR5">5</xref>, <xref ref-type="bibr" rid="CR6">6</xref>]. Over 1 billion people in the world suffer from chronic respiratory diseases. They represent one of the priorities of the European Union (3053rd and 3131st Conclusions of the European Union Council, 2010 and 2011) [<xref ref-type="bibr" rid="CR7">7</xref>, <xref ref-type="bibr" rid="CR8">8</xref>], World Health Organization (WHO 2013–2020 Noncommunicable Disease Action Plan) and the United Nations (High Level meeting on Non-Communicable Diseases, 2011) [<xref ref-type="bibr" rid="CR9">9</xref>]. The 2011 Polish Presidency of the European Union Council made the prevention, early diagnosis and treatment of asthma and allergic diseases a priority for the European Union’s public health policy in order to reduce health inequalities [<xref ref-type="bibr" rid="CR7">7</xref>]. The early determinants of chronic respiratory diseases were reinforced during the Cyprus Presidency of the European Union Council [<xref ref-type="bibr" rid="CR10">10</xref>]. The 2014 Italian Presidency of the European Union Council has prioritized chronic respiratory diseases. Chronic respiratory diseases represent a model of chronic diseases due to their prevalence, burden (e.g. 3 million annual deaths due to COPD), and comorbidities with other chronic diseases [<xref ref-type="bibr" rid="CR11">11</xref>].</p><p>The initiative AIRWAYS ICPs (Integrated care pathways for airway diseases) [<xref ref-type="bibr" rid="CR3">3</xref>] has been approved by the EIP on AHA as the model of chronic diseases of the B3 Action Plan. It is a GARD (Global Alliance against Chronic Respiratory Diseases, World Health Organization) Research Demonstration Project [<xref ref-type="bibr" rid="CR5">5</xref>]. It was launched by NHS England (National Health Service, Newcastle, February 2014) [<xref ref-type="bibr" rid="CR12">12</xref>] and has been endorsed by the EIP on AHA Reference Site Network.</p><p>The objectives of AIRWAYS ICPs are to launch a collaboration to develop practical multisectoral care pathways (ICPs) to reduce chronic respiratory disease burden, mortality and multimorbidity. AIRWAYS-ICPs proposes a feasible, achievable and manageable project from science to guidelines and policies using existing networks and stakeholders committed to the Action Plan B3 of the EIP on AHA and GARD [<xref ref-type="bibr" rid="CR5">5</xref>]. It is implemented and scaled up in Europe by the EIP on AHA and globally with GARD.</p><p>AIRWAYS-ICPs has strategic relevance to the European Union Health Strategy and the World Health Organization Noncommunicable Diseases Action Plan (2013–2020). It adds value to existing public health knowledge (Table <xref rid="Tab2" ref-type="table">2</xref>).<table-wrap id="Tab2"><label>Table 2</label><caption><p>List of activities implemented by AIRWAYS ICPs</p></caption><table frame="hsides" rules="groups"><thead><tr><th align="left"></th><th align="left">AIRWAYS ICPs proposal</th><th align="left">Implementation</th></tr></thead><tbody><tr><td align="left">1</td><td align="left">Proposing a common framework of care pathways for chronic respiratory diseases to facilitate comparability and trans-national initiatives, and plans targeted to all populations according to culture, health systems and income</td><td align="left">A repository is under development (PROEIPAHA) and the GARD strategy for adaptation to cultural beliefs and barriers is used [<xref ref-type="bibr" rid="CR6">6</xref>]</td></tr><tr><td align="left">2</td><td align="left">Developing a strategy for low and middle-income settings</td><td align="left">AIRWAYS ICPs uses existing WHO programmes such as the WHO GARD, WHO PEN, the essential list of drugs [<xref ref-type="bibr" rid="CR5">5</xref>, <xref ref-type="bibr" rid="CR13">13</xref>, <xref ref-type="bibr" rid="CR14">14</xref>] and management plans already successfully tested in low and middle-income countries [<xref ref-type="bibr" rid="CR13">13</xref>, <xref ref-type="bibr" rid="CR15">15</xref>, <xref ref-type="bibr" rid="CR16">16</xref>]</td></tr><tr><td align="left">3</td><td align="left">Aiding risk stratification in chronic disease patients with a common strategy</td><td align="left">A common risk stratification strategy for all chronic diseases is available [<xref ref-type="bibr" rid="CR17">17</xref>–<xref ref-type="bibr" rid="CR19">19</xref>]</td></tr><tr><td align="left">4</td><td align="left">Defining important questions on chronic respiratory diseases in the elderly</td><td align="left">Questions on asthma-COPD and rhinitis have been examined using a Delphi process (in preparation)</td></tr><tr><td align="left">5</td><td align="left">Developing integrated care pathways for chronic respiratory diseases and their comorbidities, with a specific focus on the elderly</td><td align="left">Developing ICPs for chronic respiratory diseases and their comorbidities, with a specific focus on the elderly [<xref ref-type="bibr" rid="CR20">20</xref>–<xref ref-type="bibr" rid="CR25">25</xref>]<break></break>Building a sentinel network for asthma and other allergic diseases [<xref ref-type="bibr" rid="CR26">26</xref>]</td></tr><tr><td align="left">6</td><td align="left">Tackling chronic diseases across the life cycle</td><td align="left">Chronic respiratory diseases occur along the life cycle and they should be prevented, diagnosed and managed early to promote AHA [<xref ref-type="bibr" rid="CR7">7</xref>, <xref ref-type="bibr" rid="CR8">8</xref>, <xref ref-type="bibr" rid="CR10">10</xref>, <xref ref-type="bibr" rid="CR27">27</xref>]</td></tr><tr><td align="left">7</td><td align="left">Interacting with frailty in chronic respiratory disease (EIP on AHA Action Plan A3) and defining active and healthy ageing</td><td align="left">Frailty is associated with chronic diseases and chronic respiratory disease. It is important to consider frailty in the management of chronic respiratory disease and to use an operational definition of AHA [<xref ref-type="bibr" rid="CR28">28</xref>–<xref ref-type="bibr" rid="CR33">33</xref>]</td></tr><tr><td align="left">8</td><td align="left">Implementing emerging technologies for individualised and predictive medicine in accordance with guidelines proposed by the European Commission (https://www.casym.eu)</td><td align="left">MASK (MACVIA–ARIA Sentinel NetworK) uses emerging technologies to develop a management strategy of rhinitis and asthma multimorbidity. It is available in 15 European countries [<xref ref-type="bibr" rid="CR26">26</xref>, <xref ref-type="bibr" rid="CR34">34</xref>]</td></tr><tr><td align="left">9</td><td align="left">Having a significant impact on the health of citizens in the short term (reduction of morbidity, improvement of education in children and of work in adults), the long-term (AHA), and in the development of health promotion</td><td align="left">Asthma and COPD national plans are cost-efficient. Some have been scaled up successfully [<xref ref-type="bibr" rid="CR35">35</xref>]<break></break>New hypotheses concerning the development of allergy have been recently proposed. They may lead to novel prevention strategies [<xref ref-type="bibr" rid="CR36">36</xref>, <xref ref-type="bibr" rid="CR37">37</xref>]</td></tr><tr><td align="left">10</td><td align="left">Educational activities</td><td align="left">Educational activities are part of any scaling up strategy</td></tr><tr><td align="left">11</td><td align="left">Stratification of health systems in Europe and beyond (EIP on AHA Action Plan A3, AA4-B3)</td><td align="left">DG Connect has initiated this project (Wouter, submitted)</td></tr></tbody></table></table-wrap></p></sec><sec id="Sec3"><title>Five-step framework scaling up strategy of the EIP on AHA</title><p>Scaling up is often considered as a continuous process of change and adaptation that can take different forms [<xref ref-type="bibr" rid="CR38">38</xref>]. The EIP on AHA has proposed a 5-step framework for developing an individual scaling up strategy. Area 5 has already used all these steps (Table <xref rid="Tab3" ref-type="table">3</xref>). The scaling up process of AIRWAYS ICPs has already been initiated, during an Action Plan B3 meeting in Brussels (March 2014).<table-wrap id="Tab3"><label>Table 3</label><caption><p>The 5-step framework of EIP on AHA scaling up strategy</p></caption><table frame="hsides" rules="groups"><thead><tr><th align="left">Step</th><th align="left">Scaling up strategy</th><th align="left">Individual scaling up strategy</th></tr></thead><tbody><tr><td align="left" colspan="2"><italic>What to scale up</italic></td><td align="left"></td></tr><tr><td align="left">1</td><td align="left">Database of good practices</td><td align="left"></td></tr><tr><td align="left">2</td><td align="left">Assessment of viability of the scaling up of good practices</td><td align="left"></td></tr><tr><td align="left">3</td><td align="left">Classification of good practices for local replication</td><td align="left"></td></tr><tr><td align="left" colspan="2"><italic>How to scale up</italic></td><td align="left"></td></tr><tr><td align="left">4</td><td align="left">Facilitating partnerships for scaling up</td><td align="left"></td></tr><tr><td align="left" rowspan="8">5</td><td align="left" rowspan="8">Implementation<break></break>Key success factors<break></break>and lessons learnt</td><td align="left">Planning and initiating the service</td></tr><tr><td align="left">Setting up a system for change</td></tr><tr><td align="left">Organisational process and design choices</td></tr><tr><td align="left">Training and skills for the work force</td></tr><tr><td align="left">Appropriate resourcing for equipment</td></tr><tr><td align="left">Integration of clinical record systems</td></tr><tr><td align="left">Creating capacity</td></tr><tr><td align="left">Monitoring, evaluation and dissemination</td></tr></tbody></table></table-wrap></p><p>In order to achieve a successful outcome for scaling up of innovative practice, the workforce should be appropriately educated in disease management, the necessary skills (e.g. spirometry, inhaler technique) should be present, and sufficient capacity made available both for training and the extra time necessary in consultation with the individual patient. These were critical factors in achieving success in the Finnish asthma and COPD ten year plans [<xref ref-type="bibr" rid="CR39">39</xref>]. Clinical recording systems need to be integrated to facilitate audit and appropriate sharing of clinical records.</p></sec><sec id="Sec4"><title>Application of the EIP on AHA scaling up strategy to chronic respiratory diseases</title><sec id="Sec5"><title>Good practices in chronic respiratory diseases</title><sec id="Sec6"><title>AIRWAYS ICPs</title><p>Six commitments for action were submitted to the EIP on AHA to support AIRWAYS ICPs. Their good practices are complementary for the scaling up strategy (Table <xref rid="Tab4" ref-type="table">4</xref>).<table-wrap id="Tab4"><label>Table 4</label><caption><p>Good practices of the EIP on AHA Commitments for Action on chronic respiratory diseases</p></caption><table frame="hsides" rules="groups"><thead><tr><th align="left"></th><th align="left">Activity</th><th align="left"></th><th align="left">Expertise</th></tr></thead><tbody><tr><td align="left">MACVIA-LR (Languedoc Roussillon)</td><td align="left">AIRWAYS ICPs<break></break>Noncommunicable Diseases global approach of multimorbidity<break></break>Frailty and chronic respiratory disease, a social approach<break></break>MASK<break></break>Eurobiomed</td><td align="left">See Table <xref rid="Tab2" ref-type="table">2</xref></td><td align="left">Founder of AIRWAYS ICPs<break></break>Uniform definition of Noncommunicable Diseases severity and control with implementation in rural remote areas and rheumatology<break></break>Definition of AHA and implementation at the social level with the French national retirement fund (CARSAT)<break></break>ICT solution for rhinitis and asthma<break></break>EUROBIOMED is the catalyst of the health sector in the Provence-Alpes-Côte d’Azur and Languedoc-Roussillon regions. We provide resources and initiatives to help life science companies achieve their business goals and improve life through innovations in health</td></tr><tr><td align="left">Finland</td><td align="left">Finnish asthma, COPD and allergy plans</td><td align="left">[<xref ref-type="bibr" rid="CR39">39</xref>–<xref ref-type="bibr" rid="CR41">41</xref>]</td><td align="left">Finnish plans for asthma [<xref ref-type="bibr" rid="CR40">40</xref>], allergy [<xref ref-type="bibr" rid="CR41">41</xref>] and COPD [<xref ref-type="bibr" rid="CR39">39</xref>] are the prototypes of national plans for chronic respiratory diseases globally [<xref ref-type="bibr" rid="CR42">42</xref>]</td></tr><tr><td align="left">Norway</td><td align="left">Deployment of the Finnish allergy plan to Norwegian regions</td><td align="left">[<xref ref-type="bibr" rid="CR43">43</xref>]</td><td align="left">Deployment of the Finnish allergy plan to all the regions of Norway. This expertise can be used to deploy national plans to regions<break></break>A European generic platform to reduce the allergy burden was created based upon the Finnish Asthma and Allergy plan</td></tr><tr><td align="left">Poland</td><td align="left">Senioral policy of Poland following the EIP on AHA recommendations including the 2011 EU Council recommendations</td><td align="left">[<xref ref-type="bibr" rid="CR7">7</xref>, <xref ref-type="bibr" rid="CR8">8</xref>]<break></break>[<xref ref-type="bibr" rid="CR33">33</xref>, <xref ref-type="bibr" rid="CR44">44</xref>]</td><td align="left">The Commitment for Action of Poland was the initiator of the EU Council policy on chronic respiratory disease in children [<xref ref-type="bibr" rid="CR7">7</xref>] and further developed the senioral policy of Poland which follows the EIP on AHA proposals. This seems to be the first AHA national project</td></tr><tr><td align="left">Portugal</td><td align="left">National coordination and national plan for all chronic respiratory diseases</td><td align="left">[<xref ref-type="bibr" rid="CR45">45</xref>]</td><td align="left">The national coordination is led by the Directorate General of Health and includes all stakeholders required for a national plan which is deployed in the regions. The plan follows the Portuguese National Programme for Respiratory Diseases (PNDR)</td></tr><tr><td align="left">Turkey</td><td align="left">National coordination and<break></break>Role of the chronic respiratory disease action plan on the ministerial Noncommunicable Diseases action plan</td><td align="left">[<xref ref-type="bibr" rid="CR46">46</xref>, <xref ref-type="bibr" rid="CR47">47</xref>]</td><td align="left">The first national coordination of GARD including the Ministry of Health, WHO national office and major societies. Extremely successful programme with all public and private stakeholders of a country. Excellent example for scale up strategy</td></tr></tbody></table></table-wrap><list list-type="bullet"><list-item><p>AIRWAYS ICPs study groups exist in all but 2 European Union countries (Luxembourg, Malta). They follow the GARD model deployed in Turkey [<xref ref-type="bibr" rid="CR46">46</xref>, <xref ref-type="bibr" rid="CR47">47</xref>] and Italy [<xref ref-type="bibr" rid="CR13">13</xref>, <xref ref-type="bibr" rid="CR48">48</xref>].</p></list-item><list-item><p>Governments of countries (e.g. Lithuania, Poland, Portugal, Turkey) or regions (e.g. Emilia-Romagna) are involved in AIRWAYS ICPs. One of the commitments for action (Norway) is a joint action between the Ministry of Health of Finland and Norway [<xref ref-type="bibr" rid="CR43">43</xref>].</p></list-item></list></p></sec><sec id="Sec7"><title>Other international, national or regional projects</title><p>Many guidelines, ICPs and national plans exist for the most common chronic respiratory diseases (asthma, COPD, rhinitis).<list list-type="bullet"><list-item><p>The Finnish plans for asthma [<xref ref-type="bibr" rid="CR40">40</xref>], allergy [<xref ref-type="bibr" rid="CR41">41</xref>] and COPD [<xref ref-type="bibr" rid="CR39">39</xref>], considered to be the prototypes of national plans for chronic respiratory diseases [<xref ref-type="bibr" rid="CR42">42</xref>]. Polastma (Poland) is, in particular, derived from the asthma plan [<xref ref-type="bibr" rid="CR35">35</xref>]. A review on the European asthma plans based on the Finnish Asthma Plan is available [<xref ref-type="bibr" rid="CR42">42</xref>].</p></list-item><list-item><p>The Portuguese National Programme for Respiratory Diseases (PNDR), the first national programme including all respiratory diseases [<xref ref-type="bibr" rid="CR45">45</xref>].</p></list-item><list-item><p>In the Netherlands, the SMART-formulated collaborative National Action programme against Chronic Lung Diseases (NACL) aims to improve the cost-effectiveness of respiratory prescribing, while reducing hospitalisation days, productivity loss, adolescent smoking, and mortality due to asthma and COPD. Both the Ministry of Health and the collective Health Insurers Netherlands are funding the programme [<xref ref-type="bibr" rid="CR13">13</xref>].</p></list-item><list-item><p>Several national or regional plans on asthma, COPD, other chronic respiratory diseases and allergy.</p></list-item><list-item><p>Guidelines or strategies for asthma [<xref ref-type="bibr" rid="CR49">49</xref>–<xref ref-type="bibr" rid="CR52">52</xref>], COPD [<xref ref-type="bibr" rid="CR53">53</xref>], rhinitis [<xref ref-type="bibr" rid="CR21">21</xref>], rhinosinusitis [<xref ref-type="bibr" rid="CR54">54</xref>] or severe asthma [<xref ref-type="bibr" rid="CR55">55</xref>] (Table <xref rid="Tab5" ref-type="table">5</xref>).<table-wrap id="Tab5"><label>Table 5</label><caption><p>An example of scaling up strategy: ARIA (Allergic Rhinitis and its Impact on Asthma) [<xref ref-type="bibr" rid="CR21">21</xref>, <xref ref-type="bibr" rid="CR26">26</xref>]</p></caption><table frame="hsides" rules="groups"><tbody><tr><td align="left">Allergic rhinitis is one of the most prevalent diseases in the world (25 % of the European Union population). Although symptoms of rhinitis appear to be trivial, the disease affects social activities as well as school and work performance [<xref ref-type="bibr" rid="CR56">56</xref>]. It is often associated with or precedes asthma (including in the elderly) [<xref ref-type="bibr" rid="CR57">57</xref>, <xref ref-type="bibr" rid="CR58">58</xref>]. Allergic rhinitis has been considered to alter AHA if not appropriately managed [<xref ref-type="bibr" rid="CR7">7</xref>, <xref ref-type="bibr" rid="CR8">8</xref>]</td></tr><tr><td align="left"> ARIA, a guideline for allergic rhinitis and its multimorbidity with asthma, is the first multimorbidity guideline in chronic diseases. It was developed in the early 2000s in collaboration with the World Health Organization using the recommended methodology for guidelines (Shekelle) [<xref ref-type="bibr" rid="CR59">59</xref>]. It was updated in 2008 [<xref ref-type="bibr" rid="CR60">60</xref>]</td></tr><tr><td align="left"> It has been revised using the GRADE methodology (2010) [<xref ref-type="bibr" rid="CR22">22</xref>, <xref ref-type="bibr" rid="CR61">61</xref>, <xref ref-type="bibr" rid="CR62">62</xref>]</td></tr><tr><td align="left"> It is the most widely used guideline for rhinitis, and for rhinitis and asthma multimorbidity globally [<xref ref-type="bibr" rid="CR21">21</xref>]</td></tr><tr><td align="left"> The ARIA classification of allergic rhinitis severity has been used for the development of Health Technology Assessment guidelines, in particular in the US [<xref ref-type="bibr" rid="CR63">63</xref>]</td></tr><tr><td align="left"> ARIA recommendations have been adopted by government guidelines (Brazil, Portugal, Singapore)</td></tr><tr><td align="left"> ARIA is implemented in 64 countries and the pocket guide of the guideline has been translated into 52 languages</td></tr><tr><td align="left"> MASK-rhinitis (MACVIA–ARIA Sentinel NetworK for allergic rhinitis) is a care pathway centred around the use of Information and Communications Technology (ICT) tools and a clinical decision support system (CDSS) based on ARIA [<xref ref-type="bibr" rid="CR26">26</xref>, <xref ref-type="bibr" rid="CR34">34</xref>]. This tool can be used by older adults</td></tr><tr><td align="left"> Over 600 scientific papers have used ARIA for the classification of allergic rhinitis in clinical practice, clinical trials, as well as epidemiologic (from pre-school children to the elderly [<xref ref-type="bibr" rid="CR58">58</xref>]), basic and translational research [<xref ref-type="bibr" rid="CR21">21</xref>]</td></tr></tbody></table></table-wrap></p></list-item><list-item><p>Care pathways provided by national institutions (e.g. NICE in the UK, National Institute for Health and Care Excellence or the Haute Autorité de Santé in France, ICP for acute asthma in children in Northern Ireland).</p></list-item><list-item><p>The World Health Organization guidelines for asthma and COPD in low-income settings (WHO PEN) [<xref ref-type="bibr" rid="CR14">14</xref>].</p></list-item><list-item><p>Management plans already successfully tested in low and middle-income countries [<xref ref-type="bibr" rid="CR15">15</xref>].</p></list-item><list-item><p>A common approach to severe asthma and allergic diseases [<xref ref-type="bibr" rid="CR17">17</xref>, <xref ref-type="bibr" rid="CR19">19</xref>].</p></list-item><list-item><p>In Spain, Polibienestar Research Institute is developing a Multi-Agent Simulator for people requiring prolonged mechanical ventilation based on the validated LTCMAS [<xref ref-type="bibr" rid="CR64">64</xref>] and following the Canadian model [<xref ref-type="bibr" rid="CR65">65</xref>], which is easily replicable and transferrable to other healthcare systems and to other diseases. Moreover, this tool offers great possibilities for scaling-up and for supporting the decision-making process of health professionals and policy-makers.</p></list-item><list-item><p>Multimorbidity guidelines for chronic respiratory diseases do not exist, except for rhinitis and asthma [<xref ref-type="bibr" rid="CR21">21</xref>].</p></list-item><list-item><p>The risk for developing a COPD has only been studied in Italy and represents a chart risk applicable to the entire Europe.</p></list-item><list-item><p>Palliative approaches to care in chronic respiratory disease, and planning end-of-life decisions and care/advanced care.</p></list-item><list-item><p>Guidelines with a specific target on old age adults do not exist. A Delphi process is ongoing.</p></list-item></list></p></sec><sec id="Sec8"><title>Guidance documents for primary care</title><p>Some guidance documents are specifically directed to primary care—where most patients with chronic respiratory diseases are managed—such as COPD-Australia (Lung Foundation Australia with Thoracic Society of Australia and New Zealand) and Asthma Management in Australia (National Asthma Council Australia). IPCRG (International Primary Care Respiratory Group) has undertaken a mapping on national guidelines used by primary care for COPD, asthma, rhinitis, obstructive sleep apnea and stop smoking (<ext-link ext-link-type="uri" xlink:href="https://www.theipcrg.org/display/ResMapping">https://www.theipcrg.org/display/ResMapping</ext-link>).</p></sec></sec><sec id="Sec9"><title>Database</title><p>A centralized repository of evidence is developed to preserve data throughout the lifecycle of the project. The repository is under development by the Commission.</p></sec><sec id="Sec10"><title>Assessment of viability of the scaling up of good practices</title><p>The members of AIRWAYS ICPs, ARIA and GARD [<xref ref-type="bibr" rid="CR6">6</xref>, <xref ref-type="bibr" rid="CR13">13</xref>, <xref ref-type="bibr" rid="CR48">48</xref>] have experience in working together and have already scaled up several chronic respiratory disease good practices. Scaling up for ARIA and GARD follows the 7 key characteristics of the CORRECT features: Credible, Observable, Relevant, Relative advantage, Easy and Compatible [<xref ref-type="bibr" rid="CR66">66</xref>, <xref ref-type="bibr" rid="CR67">67</xref>]. The success of the scaling up strategy and its long-term viability (over 15 years for ARIA and 8 years in GARD) has been demonstrated. GARD has been scaled up in several countries at governmental levels [<xref ref-type="bibr" rid="CR13">13</xref>, <xref ref-type="bibr" rid="CR46">46</xref>–<xref ref-type="bibr" rid="CR48">48</xref>].</p><p>Members of 13 EIP on AHA Reference Sites have agreed on the AIRWAYS ICPs concept and are co-authors of the paper [<xref ref-type="bibr" rid="CR3">3</xref>]. A meeting of all EIP on AHA Reference Sites was co-organised by the Région LR, North England and the EIP on AHA Reference Site Collaborative Network to scale up AIRWAYS ICPs in all Reference Sites (October 21, 2014).</p><p>The viability of ARIA and GARD has been demonstrated. The viability of AIRWAYS ICPs will be analysed according to the set of parameters provided by the Commission in the near future. The analysis will be carried out within 6 months by an AIRWAYS ICPs expert panel and revised by an independent expert panel (6 additional months). The meeting for the analysis of the viability took place in Lisbon (Directorate General of Health of Portugal), July 1-2, 2015 in collaboration with the World Health Organization GARD [<xref ref-type="bibr" rid="CR68">68</xref>].</p></sec><sec id="Sec11"><title>Classification of good practices for replication</title><p>Feasibility has been reviewed for the Finnish Asthma Plan (Table <xref rid="Tab6" ref-type="table">6</xref>). It is expected that AIRWAYS ICPs following the expertise raised in ARIA and GARD will have a similar feasibility.<table-wrap id="Tab6"><label>Table 6</label><caption><p>Classification of good practices for replication: the example of the Finnish Asthma Plan [<xref ref-type="bibr" rid="CR40">40</xref>]</p></caption><table frame="hsides" rules="groups"><thead><tr><th align="left">Items</th><th align="left"></th><th align="left">Example of the Finnish Asthma Plan</th></tr></thead><tbody><tr><td align="left" rowspan="3">Knowledge—gaps</td><td align="left">Between knowledge and practice (research, specific)</td><td align="left">The plan has been [<xref ref-type="bibr" rid="CR69">69</xref>] tested and validated at the national level [<xref ref-type="bibr" rid="CR40">40</xref>]</td></tr><tr><td align="left">Existence of tested solutions (good examples, specific)</td><td align="left">It has shown cost-effective reduction of hospitalisations, deaths and disability</td></tr><tr><td align="left">Large variations between countries (good examples, general)</td><td align="left">The Finnish Asthma Plan has been deployed successfully to over 25 countries globally including developing countries. The same effectiveness has been demonstrated [<xref ref-type="bibr" rid="CR70">70</xref>, <xref ref-type="bibr" rid="CR71">71</xref>]. The Finnish Asthma Plan is considered to be the model of all asthma plans in the world [<xref ref-type="bibr" rid="CR35">35</xref>]</td></tr><tr><td align="left" rowspan="2">Reaction time</td><td align="left">Calendar (time needed for implementation</td><td align="left" rowspan="2">The Finnish Asthma Plan was a 10-year plan. Most indicators were found to change significantly after 24–36 months, but the effectiveness improved over the 10-year programme. In Brazil, an impact at population morbidity indicators was found after 24 months</td></tr><tr><td align="left">Effects/visibility (time needed to assess impact)</td></tr><tr><td align="left">Stewardship</td><td align="left">Administrative and political capacity. Leadership, inside the health sector and in other sectors (Health in All Policies)</td><td align="left">Many plans are national plans supported by the Ministry of Health or the department of health of the region (e.g. Minas Gerais, Brazil). All stakeholders including health (specialists, GPs, nurses, pharmacists, other health care professionals) and social carers as well as patients are involved in the plan. A specific action is devoted to education, coaching and training</td></tr><tr><td align="left" rowspan="4">Political agenda</td><td align="left">Electoral programme</td><td align="left"></td></tr><tr><td align="left">Social concerns</td><td align="left">A specific attention has been put on social concerns and a promotion in the country at all levels (citizens and patients, health and social carers, politicians) has been continuously monitored</td></tr><tr><td align="left">Crisis</td><td align="left"></td></tr><tr><td align="left">International institutions recommendations/conditions</td><td align="left">The Finnish Asthma Plan and its follow up (the Finnish Allergy Programme) [<xref ref-type="bibr" rid="CR41">41</xref>, <xref ref-type="bibr" rid="CR72">72</xref>] has been endorsed by the Finnish Ministry of Health. Some plans in developed and developing countries (globally) are also under the Ministry of Health leadership and some have been endorsed by WHO GARD (GARD demonstration project). The Finnish Asthma Plan is listed in asthma guidelines</td></tr><tr><td align="left">Costs and affordability</td><td align="left">It is important to consider the cost of the programme for selecting priority areas for investment. Certain decisions could need relevant investments (e.g. equipment, personnel, etc.) while others involve low direct economic cost (e.g. anti-tobacco strategies and legislation). The costs of a programme have to be considered in the context of the economic situation of the country (GDP/inhabitant; expansion/recession/stagnation; private and public debt; etc.)</td><td align="left">The Finnish Asthma Plan is comprehensive and includes treatments, preventive measures (e.g. tobacco smoking), action plans, education at all levels. It was found to be cost-effective. This has been demonstrated in Finland, but also in other countries such as Brazil [<xref ref-type="bibr" rid="CR42">42</xref>, <xref ref-type="bibr" rid="CR73">73</xref>, <xref ref-type="bibr" rid="CR74">74</xref>]. Thus, reducing the asthma burden is cost-effective in countries with different GDP/inhabitant, health and economic systems</td></tr><tr><td align="left">Acceptability</td><td align="left">The support or the opposition that a certain policy is going to attract</td><td align="left">The Plan was extremely well accepted in all countries where it was promoted [<xref ref-type="bibr" rid="CR42">42</xref>]</td></tr><tr><td align="left" rowspan="2">Monitoring capability</td><td align="left">The availability of the necessary information to monitor the starting point, the processes and the outcomes</td><td align="left">Baseline information on the burden of asthma is available even though in most developing countries there is no information [<xref ref-type="bibr" rid="CR75">75</xref>]. Information on the success of the programme was easily documented [<xref ref-type="bibr" rid="CR35">35</xref>, <xref ref-type="bibr" rid="CR70">70</xref>, <xref ref-type="bibr" rid="CR71">71</xref>] and carefully monitored</td></tr><tr><td align="left">It highlights also the importance of transparency</td><td align="left">National (or regional) statistics are transparent</td></tr><tr><td align="left" rowspan="4">Contextual factors</td><td align="left">Demographics</td><td align="left">The Finnish Asthma Plan was a national plan covering the entire country. Some plans are regional plans (Bahia or Minais Gerais)</td></tr><tr><td align="left">Social and economic conditions</td><td align="left">The Finnish Asthma Plan targeted the entire country. The Minais Gerais plan targets children in deprived areas (“favelas”) who are at high risk of severe exacerbations and death [<xref ref-type="bibr" rid="CR76">76</xref>] as does the severe asthma programme established in Bahia, dealing with children and adults [<xref ref-type="bibr" rid="CR70">70</xref>]</td></tr><tr><td align="left">Cultural factors</td><td align="left" rowspan="2">In Finland, barriers are not very important. However, in many developing countries, cultural barriers have been carefully considered according to a WHO report [<xref ref-type="bibr" rid="CR6">6</xref>]. They include culture, gender issues, socio-economic inequalities, health care access, access to essential medications and techniques</td></tr><tr><td align="left">Other non-health care determinants of health that impact on population health and wellbeing</td></tr></tbody></table></table-wrap></p></sec><sec id="Sec12"><title>Facilitating partnership for scaling up</title><sec id="Sec13"><title>Collaborator’s role</title><p>The ARIA programme includes over 300 members and AIRWAYS ICPs includes 445 members. The paper describing the AIRWAYS ICPs proposal is co-authored by 250 members (all stakeholders: health care professionals, social carers, patients, government officers, methodologists, etc.) [<xref ref-type="bibr" rid="CR3">3</xref>]. All of the members are very committed to the implementation of AIRWAYS ICPs. National and regional groups have been initiated in all but 2 European Union countries. In countries where health care is regionalised [<xref ref-type="bibr" rid="CR59">59</xref>], many regional groups are in place.</p></sec><sec id="Sec14"><title>Role of scientific societies</title><p>AIRWAYS ICPs is in line with the mission and vision of scientific societies which aim to (1) promote research, (2) collect, assess and diffuse scientific information, (3) represent a scientific reference body for other scientific, health and political organisations and an advocate towards political organisation and the general public, (4) encourage and provide training, continuous education and professional development and (5) collaborate with patients and lay organisations in the area of their field in order to lead the way towards better understanding, prevention, management and eventual cure of diseases. The European Academy of Allergy and Clinical Immunology (EAACI), the European Respiratory Society (ERS), the European Rhinology Society (ERS), the European Union Geriatric Medicine Society (EUGMS), the International Academy of Pediatrics and the International Primary Care Respiratory Group (IPCRG) are the major societies in Europe of their respective field and are all members of AIRWAYS ICPs. A recent meeting on precision medicine in airways and allergic diseases was held at the European Union Parliament with these societies [<xref ref-type="bibr" rid="CR77">77</xref>, <xref ref-type="bibr" rid="CR78">78</xref>]. The activities of IPCRG are summarized in Additional file <xref rid="MOESM1" ref-type="media">1</xref>.</p></sec><sec id="Sec15"><title>Role of patient’s organisations</title><p>The goal and rationale of patient involvement in medical decisions is patient empowerment. Empowered patients know their disease. Patient empowerment commences with the initial consultations at the primary care level encompassing discussions about the patient’s ideas, concerns and expectations coupled with patient education about the specific disease process, what can be done to ameliorate the disease and ultimately self-management. Patients have the skills and motivation to take good care in their everyday life, to adjust their treatment, and are prepared for new or potentially exacerbating situations. They are able to detect side-effects, contact healthcare professionals when necessary and they adhere to the treatment regime. Many tools support empowerment, shared decision making models and patient education. Patient empowerment should be included in the health care professional’s curriculum. For an optimal dissemination of good practices, there is a need for patient involvement and empowerment.</p><p>There are recommendations to secure patient organization/patient involvement at national (e.g. The Netherlands ZonMW) and also at European Union level [<xref ref-type="bibr" rid="CR79">79</xref>, <xref ref-type="bibr" rid="CR80">80</xref>].</p><p>EFA (European Federation of Allergy and airways diseases patient’s association), the major patient’s organisation for respiratory and allergic diseases in Europe, has been very active for AIRWAYS ICPs [<xref ref-type="bibr" rid="CR77">77</xref>, <xref ref-type="bibr" rid="CR78">78</xref>].</p></sec><sec id="Sec16"><title>Diffusion of good practices</title><p>All European Union countries should be included.</p><p>The European Geriatric Medicine, the official organ of the European Union Geriatric Medicine Society (EUGMS), has initiated a column of the EIP on AHA to publish important activities of the EIP on AHA in order to inform the medical community [<xref ref-type="bibr" rid="CR2">2</xref>]. Several papers have already been published [<xref ref-type="bibr" rid="CR2">2</xref>, <xref ref-type="bibr" rid="CR29">29</xref>, <xref ref-type="bibr" rid="CR44">44</xref>, <xref ref-type="bibr" rid="CR81">81</xref>–<xref ref-type="bibr" rid="CR85">85</xref>].<list list-type="bullet"><list-item><p><italic>Reference Site Network</italic>: The Reference Site Network is already committed to AIRWAYS-ICPs (decision taken during the Montpellier meeting).</p></list-item><list-item><p><italic>Action Groups</italic>: Area 5 of Action Group B3 is leading AIRWAYS ICPs.</p></list-item><list-item><p><italic>Event and dedicated scaling up/twinning sessions</italic>: Several events have already taken place (Table <xref rid="Tab7" ref-type="table">7</xref>).<table-wrap id="Tab7"><label>Table 7</label><caption><p>AIRWAYS ICPs 2014 events</p></caption><table frame="hsides" rules="groups"><thead><tr><th align="left">Date</th><th align="left">Location</th><th align="left">Event and goals</th></tr></thead><tbody><tr><td align="left">27-02</td><td align="left">Newcastle (UK)</td><td align="left">Launch of AIRWAYS ICPs by Dr. M Bewick, Deputy National Medical Director of NHS England, [<xref ref-type="bibr" rid="CR12">12</xref>]</td></tr><tr><td align="left">12-05</td><td align="left">Athens (Greece)</td><td align="left">AIRWAYS ICPs was presented to the EIP on AHA</td></tr><tr><td align="left">09-06</td><td align="left">Copenhagen (Denmark)</td><td align="left">European Academy of Allergy and Clinical Immunology (EAACI). A symposium was organized (1000 participants) and a working meeting held immediately after: AIRWAYS ICPs and MACVIA–ARIA [<xref ref-type="bibr" rid="CR26">26</xref>]</td></tr><tr><td align="left">17-08</td><td align="left">Bahia (Brazil)</td><td align="left">WHO GARD annual meeting. Presentation of AIRWAYS ICPs and MACVIA–ARIA to the GARD members and WHO. Acceptance of AIRWAYS ICPs to strengthen the 2013–2020 Noncommunicable Diseases WHO Action Plan [<xref ref-type="bibr" rid="CR86">86</xref>, <xref ref-type="bibr" rid="CR87">87</xref>]</td></tr><tr><td align="left">16-09</td><td align="left">Rotterdam (NL)</td><td align="left">Annual meeting of the European Union Geriatric Medicine Society (EUGMS): Presidential lecture on AIRWAYS (T Strandberg, President of the Society)</td></tr><tr><td align="left">09-10</td><td align="left">Dubrovnik (Croatia)</td><td align="left">Annual meeting of the Croatian Respiratory Society. AIRWAYS ICPs and MACVIA–ARIA were presented (M Niculinic, President of the Society)</td></tr><tr><td align="left">16-10</td><td align="left">Rome (Italy)</td><td align="left">The Italian Presidency of the European Union Council has made chronic respiratory diseases one of the priorities. A GARD Italy meeting was held at the Ministry of Health. AIRWAYS ICPs was presented among other projects to be included in the Priority</td></tr><tr><td align="left">20-10</td><td align="left">Montpellier (France)</td><td align="left">The Region Languedoc Roussillon (in collaboration with the region North England and the EIP on AHA Reference Site Collaborative Network) invited one member from each Reference Site to scale up AIRWAYS ICPs. The Collaborative Network decided to include AIRWAYS ICPs in its priorities for scaling up and implementation (M Bewick, R Pengelly, Secretary of State of Northern Ireland) [<xref ref-type="bibr" rid="CR28">28</xref>, <xref ref-type="bibr" rid="CR29">29</xref>]</td></tr><tr><td align="left">05-11</td><td align="left">Salzburg (Austria)</td><td align="left">Annual meeting of the Austrian Allergy Society</td></tr><tr><td align="left">07-11</td><td align="left">Guangzhou (China)</td><td align="left">Annual meeting: Discussion for the deployment of AIRWAYS ICPs and MACVIA–ARIA in China (NS Zhong, former President of the Chinese Medical Association) [<xref ref-type="bibr" rid="CR88">88</xref>]</td></tr><tr><td align="left">20-11</td><td align="left">Oslo (Norway)</td><td align="left">Commitments for Action Oslo, Helsinki and Montpellier (K Lodrup Carlsen, T Haahtela, JB). The agreement for the deployment of the Finnish Allergy Programme in Norway was discussed at the Ministry of Health [<xref ref-type="bibr" rid="CR43">43</xref>]</td></tr></tbody></table></table-wrap></p></list-item><list-item><p><italic>Network of excellence centres in respiratory and allergic diseases</italic>: It includes the Commitments for Action (EIP on AHA action Plan B3), Reference Sites of the EIP AHA, the Global Allergy and Asthma European Network (GA<sup>2</sup>LEN) and members of AIRWAYS ICPs. GA<sup>2</sup>LEN, a Sixth European Union Framework Programme for Research and Technological Development (FP6) Network of Excellence, was created in 2005 as a vehicle to ensure excellence in research bringing together research and clinical institutions to combat fragmentation in the European research area and to tackle allergy in its globality [<xref ref-type="bibr" rid="CR89">89</xref>]. The GA<sup>2</sup>LEN network has benefited greatly from the voluntary efforts of researchers who are strongly committed to this model of pan-European collaboration. The network was organized in order to increase networking for scientific and clinical projects in allergy and asthma around Europe.</p></list-item></list></p></sec></sec><sec id="Sec17"><title>Implementation, key success factors and lessons learnt</title><sec id="Sec18"><title>Planning and initiating the service</title><p><list list-type="bullet"><list-item><p><italic>Needs for AIRWAYS ICPs</italic>, in particular in elderly adults and co-morbid diseases, are clear. AIRWAYS ICPs was developed following the research priorities set by the World Health Organization on chronic respiratory diseases [<xref ref-type="bibr" rid="CR90">90</xref>].</p></list-item><list-item><p><italic>The strategy, the road map and the first implementation results</italic> have been published [<xref ref-type="bibr" rid="CR4">4</xref>].</p></list-item><list-item><p><italic>ICPs for asthma have been shown to be highly cost</italic>-<italic>effective in</italic> different settings [<xref ref-type="bibr" rid="CR15">15</xref>, <xref ref-type="bibr" rid="CR35">35</xref>]. Studies in developed and developing countries have shown a cost-effective reduction of hospitalisations and mortality.</p></list-item></list></p></sec><sec id="Sec19"><title>Setting up a system for change</title><p><list list-type="bullet"><list-item><p><italic>Good understanding</italic>: The members of ARIA, GARD and AIRWAYS ICPs have perceived the need for innovation, and consider it beneficial and congruent with central ideas and concepts. Deployment has been made to all stakeholders including patients and citizens. The results of the ARIA and GARD initiatives are clear [<xref ref-type="bibr" rid="CR13">13</xref>, <xref ref-type="bibr" rid="CR46">46</xref>, <xref ref-type="bibr" rid="CR91">91</xref>–<xref ref-type="bibr" rid="CR98">98</xref>]. Since the same methodology is used for AIRWAYS ICPs enhanced by the EIP on AHA scaling up strategy, there is no reason for a lack of understanding. The present paper is co-authored by over 450 authors from 72 countries in order to enhance understanding for different cultures, settings, health systems and languages.</p></list-item><list-item><p><italic>Implementation of emerging technologies for predictive and personalised medicine</italic>. Systems medicine is an emerging discipline [<xref ref-type="bibr" rid="CR18">18</xref>, <xref ref-type="bibr" rid="CR77">77</xref>, <xref ref-type="bibr" rid="CR78">78</xref>, <xref ref-type="bibr" rid="CR99">99</xref>]. It combines high-throughput analyses of all human genes and their products with computational, functional and clinical studies. The aim is to gain detailed understanding of disease mechanisms, and how they vary between different patient groups. This understanding can be exploited for predictive and personalised medicine, according to guidelines proposed by the European Commission (<ext-link ext-link-type="uri" xlink:href="https://www.casym.eu">https://www.casym.eu</ext-link>). The first implementations may reach the clinic within the next five years for serious diseases that require costly treatments [<xref ref-type="bibr" rid="CR100">100</xref>].</p></list-item><list-item><p><italic>Political endorsement</italic>: Several meetings have been organised by the European Union. In particular, the Polish Priority of the Council [<xref ref-type="bibr" rid="CR7">7</xref>, <xref ref-type="bibr" rid="CR8">8</xref>] which “WELCOMES existing networks and alliances, such as the Global Allergy and Asthma European Network (GA<sup>2</sup>LEN) and Global Alliance against Respiratory Diseases (GARD)”. There are recommendation: (i) to give appropriate consideration to prevention, early diagnosis and treatment, (ii) to strengthen cooperation with relevant stakeholders, (iii)to exchange best practices, (iv) to support national centres and existing international research networks (v) to find cost-effective procedures by using health technology assessment, (vi) to improve health care system standards relating to chronic respiratory diseases, (vii) to consider the use of e-Health tools and innovative technologies for prevention, early diagnosis and treatment of chronic respiratory diseases, and finally (viii) to support Member States by the “Commission developing and implementing effective policies, improving networking among institutions responsible for the implementation of programmes.”</p></list-item></list></p><p>A meeting at the European Union Parliament under the leadership of the Cyprus Presidency of the European Union Council [<xref ref-type="bibr" rid="CR10">10</xref>] and a GARD meeting at the Italian Ministry of Health during the Presidency of the Council both reinforced the importance of chronic respiratory diseases for their early detection and management to improve AHA. The present document was presented at a meeting in Lisbon, Portugal (July 1–2, 2015) organised by the Reference Site Network of the EIP on AHA in collaboration with European Union regions and the Directorate General of Health.</p><p>MACVIA-LR is supported by a strong political endorsement at the regional level. ARIA has been adopted by several governmental policies. AIRWAYS ICPs has been launched in collaboration with NHS England, Scotland, Northern Ireland, the Ministry of Health of Portugal, Poland and Lithuania and several governments of regions (e.g. Emilia Romagna, Basque Country).<list list-type="bullet"><list-item><p><italic>Engagement of relevant stakeholders</italic>: In ARIA, GARD and AIRWAYS ICPs, all relevant stakeholders have been included and are highly motivated: health care professionals (physicians, pharmacists, nurses, physiotherapists and others), social workers, policy makers. A special effort has been made for patient empowerment. A European Union Parliament session led by EFA, the largest European patients’ organisation in asthma and airway diseases, has been organised in collaboration with MeDALL (Mechanisms of the Development of Allergy, FP7 project) [<xref ref-type="bibr" rid="CR36">36</xref>, <xref ref-type="bibr" rid="CR37">37</xref>], in May 2015. Professional societies and groups should be enlisted as active collaborators in order to enhance and even drive uptake at the country level.</p></list-item><list-item><p><italic>Financial viability and business model</italic>: It has been shown that the implementation of the Finnish national plans, ARIA and GARD does not require large resources. However, AIRWAYS ICPs will require arrangements for the reimbursement of the services.</p></list-item></list></p></sec><sec id="Sec20"><title>Organisational process and design choices</title><p><list list-type="bullet"><list-item><p><italic>Investing in human capital</italic>: Training and reskilling the work force is an essential and fundamental component of AIRWAYS ICPs. This may require initial and continuing investment to ensure that the workforce possesses the appropriate knowledge, skills and equipment to fulfil its roles, as show by some very successful ARIA and GARD initiatives. AIRWAYS ICPs should shall go a step further, however, and be fully implemented countrywide. The EIP on AHA Reference Site Network has offered its help. The present paper has been co-authored by many professional leaders from over 70 countries to build a global momentum.</p></list-item><list-item><p><italic>Integrating ICT solutions</italic>: Telemedicine represents a possible specific advanced tool of ICT in chronic respiratory disease management and secondary prevention. ICT solutions are integrated to support AIRWAYS ICPs implementation and the MACVIA–ARIA Sentinel NetworK has been launched in Copenhagen (June 9, 2014). A clinical decision support system (CDSS) is being built and should be available at the end of the year. This system may form the prototype for a more complex one for asthma, COPD, other chronic respiratory diseases and co-morbidities.</p></list-item><list-item><p><italic>Organisational changes</italic>: Currently under discussion but will require flexibility in order to adapt to the needs of different areas.</p></list-item></list></p></sec><sec id="Sec21"><title>Monitoring, evaluation and dissemination</title><p>These activities have been initiated by ARIA and GARD at the international level, but they are also part of the national and regional plans for chronic respiratory diseases. The Area 5 programme on chronic respiratory diseases will benefit from previous expertise, successes and failures to propose refined and updated activities.<list list-type="bullet"><list-item><p><italic>Assessment indicators</italic>: In asthma and COPD, hospitalisation rates and mortality are two indicators of interest and are responsive to change within 2–3 years. In rhinitis, these indicators cannot be used. Control is applicable to asthma, COPD and/or rhinitis and quality of life is applicable to all 3 diseases. An economic evaluation was found to be effective in asthma in many countries [<xref ref-type="bibr" rid="CR40">40</xref>, <xref ref-type="bibr" rid="CR74">74</xref>].</p></list-item><list-item><p><italic>Mutual learning</italic>: Learning Networks for learning and sharing best practices are in place for chronic respiratory diseases. Scientific societies and patient’s organisations are of importance in the process.</p></list-item><list-item><p><italic>Dissemination activities</italic>: One of the strengths of ARIA and GARD, and also already AIRWAYS ICPs, is the great ability to disseminate information and guidelines in countries of the European Union and globally.</p></list-item><list-item><p><italic>Scaling up of the new good practices</italic>: Another strength of ARIA and GARD is the capacity to scale up good practices in countries of the European Union and elsewhere.</p></list-item></list></p></sec></sec></sec><sec id="Sec22" sec-type="conclusion"><title>Conclusions</title><p>The scaling up strategy of AIRWAYS ICPs confirms
that the proposed strategy of the EIP on AHA is simple and easy to follow. It may be used as a model for the scaling up strategies of other projects of the EIP on
AHA.</p></sec></body><back><app-group><app id="App1"><sec id="Sec23"><title>Additional file</title><p><media position="anchor" xlink:href="13601_2016_116_MOESM1_ESM.docx" id="MOESM1"><caption><p>10.1186/s13601-016-0116-9 IPCRG scaling up activities.</p></caption></media></p></sec></app></app-group><glossary><title>Abbreviations</title><def-list><def-item><term>AIRWAYS ICPs</term><def><p>integrated care pathways for airway diseases</p></def></def-item><def-item><term>ARIA</term><def><p>Allergic Rhinitis and its Impact on Asthma</p></def></def-item><def-item><term>COPD</term><def><p>chronic obstructive pulmonary disease</p></def></def-item><def-item><term>DG</term><def><p>Directorate General</p></def></def-item><def-item><term>EIP on AHA</term><def><p>European Innovation Partnership on Active and Healthy Ageing</p></def></def-item><def-item><term>GA<sup>2</sup>LEN</term><def><p>Global Allergy and Asthma European Network (FP6)</p></def></def-item><def-item><term>GARD</term><def><p>WHO Global Alliance against Chronic Respiratory Diseases</p></def></def-item><def-item><term>ICP</term><def><p>integrated care pathway</p></def></def-item><def-item><term>IPCRG</term><def><p>International Primary Care Respiratory Group</p></def></def-item><def-item><term>MACVIA-LR</term><def><p>Contre les MAladies Chroniques pour un VIeillissement Actif (Fighting chronic diseases for active and healthy ageing)</p></def></def-item><def-item><term>MASK</term><def><p>MACVIA–ARIA Sentinel NetworK</p></def></def-item><def-item><term>NHS</term><def><p>National Health Service</p></def></def-item><def-item><term>WHO</term><def><p>World Health Organization</p></def></def-item><def-item><term>VAS</term><def><p>visual analogue scale</p></def></def-item></def-list></glossary><ack><title>Authors’ contributions</title><p>All the authors participated in scaling up strategy of AIRWAYS ICPs. 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