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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Therapeutic actions of curcumin in bone disorders</title><author><name sortKey="Rohanizadeh, Ramin" sort="Rohanizadeh, Ramin" uniqKey="Rohanizadeh R" first="Ramin" last="Rohanizadeh">Ramin Rohanizadeh</name><affiliation><nlm:aff id="a1"><institution>Advanced Drug Delivery Group, Faculty of Pharmacy, University of Sydney</institution>, Sydney, New South Wales,<country>Australia</country></nlm:aff></affiliation></author><author><name sortKey="Deng, Yi" sort="Deng, Yi" uniqKey="Deng Y" first="Yi" last="Deng">Yi Deng</name><affiliation><nlm:aff id="a1"><institution>Advanced Drug Delivery Group, Faculty of Pharmacy, University of Sydney</institution>, Sydney, New South Wales,<country>Australia</country></nlm:aff></affiliation></author><author><name sortKey="Verron, Elise" sort="Verron, Elise" uniqKey="Verron E" first="Elise" last="Verron">Elise Verron</name><affiliation><nlm:aff id="a1"><institution>Advanced Drug Delivery Group, Faculty of Pharmacy, University of Sydney</institution>, Sydney, New South Wales,<country>Australia</country></nlm:aff></affiliation><affiliation><nlm:aff id="a2"><institution>INSERM, U791, LIOAD</institution>, Nantes,<country>France</country></nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">26962450</idno><idno type="pmc">4774085</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774085</idno><idno type="RBID">PMC:4774085</idno><idno type="doi">10.1038/bonekey.2016.20</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">000884</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000884</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Therapeutic actions of curcumin in bone disorders</title><author><name sortKey="Rohanizadeh, Ramin" sort="Rohanizadeh, Ramin" uniqKey="Rohanizadeh R" first="Ramin" last="Rohanizadeh">Ramin Rohanizadeh</name><affiliation><nlm:aff id="a1"><institution>Advanced Drug Delivery Group, Faculty of Pharmacy, University of Sydney</institution>, Sydney, New South Wales,<country>Australia</country></nlm:aff></affiliation></author><author><name sortKey="Deng, Yi" sort="Deng, Yi" uniqKey="Deng Y" first="Yi" last="Deng">Yi Deng</name><affiliation><nlm:aff id="a1"><institution>Advanced Drug Delivery Group, Faculty of Pharmacy, University of Sydney</institution>, Sydney, New South Wales,<country>Australia</country></nlm:aff></affiliation></author><author><name sortKey="Verron, Elise" sort="Verron, Elise" uniqKey="Verron E" first="Elise" last="Verron">Elise Verron</name><affiliation><nlm:aff id="a1"><institution>Advanced Drug Delivery Group, Faculty of Pharmacy, University of Sydney</institution>, Sydney, New South Wales,<country>Australia</country></nlm:aff></affiliation><affiliation><nlm:aff id="a2"><institution>INSERM, U791, LIOAD</institution>, Nantes,<country>France</country></nlm:aff></affiliation></author></analytic><series><title level="j">BoneKEy Reports</title><idno type="eISSN">2047-6396</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Curcumin is the active component of turmeric extract derived from the Curcuma longa plant. In the last decade, curcumin has raised a considerable interest in medicine owing to its negligible toxicity and multiple therapeutic actions including anti-cancer, anti-inflammatory and anti-microbial activities. Among the various molecular targets of curcumin, some are involved in bone remodeling, which strongly suggests that curcumin can affect the skeletal system. The review sheds light on the current and potential applications of curcumin to treat bone disorders characterized by an excessive resorption activity. Within the scope of this review, the novel formulations of curcumin to overcome its physico-chemical and pharmacokinetic constraints are also discussed.</p></div></front></TEI><pmc article-type="review-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Bonekey Rep</journal-id><journal-id journal-id-type="iso-abbrev">Bonekey Rep</journal-id><journal-title-group><journal-title>BoneKEy Reports</journal-title></journal-title-group><issn pub-type="epub">2047-6396</issn><publisher><publisher-name>Nature Publishing Group</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">26962450</article-id><article-id pub-id-type="pmc">4774085</article-id><article-id pub-id-type="pii">bonekey201620</article-id><article-id pub-id-type="doi">10.1038/bonekey.2016.20</article-id><article-categories><subj-group subj-group-type="heading"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title>Therapeutic actions of curcumin in bone disorders</article-title><alt-title alt-title-type="short">Therapeutic actions of curcumin</alt-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Rohanizadeh</surname><given-names>Ramin</given-names></name><xref ref-type="aff" rid="a1">1</xref></contrib><contrib contrib-type="author"><name><surname>Deng</surname><given-names>Yi</given-names></name><xref ref-type="aff" rid="a1">1</xref></contrib><contrib contrib-type="author"><name><surname>Verron</surname><given-names>Elise</given-names></name><xref ref-type="corresp" rid="c1">a</xref><xref ref-type="aff" rid="a1">1</xref><xref ref-type="aff" rid="a2">2</xref></contrib><aff id="a1"><label>1</label><institution>Advanced Drug Delivery Group, Faculty of Pharmacy, University of Sydney</institution>, Sydney, New South Wales,<country>Australia</country></aff><aff id="a2"><label>2</label><institution>INSERM, U791, LIOAD</institution>, Nantes,<country>France</country></aff></contrib-group><author-notes><corresp id="c1"><label>a</label><institution>INSERM U791, Université de Nantes, Faculté de Chirurgie Dentaire</institution>, 1, place Alexi Ricordeau, Nantes 44042, <country>France</country>. E-mail: <email>elise.verron@univ-nantes.fr</email></corresp></author-notes><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>02</day><month>03</month><year>2016</year></pub-date><volume>5</volume><elocation-id>793</elocation-id><history><date date-type="received"><day>28</day><month>10</month><year>2015</year></date><date date-type="accepted"><day>28</day><month>01</month><year>2016</year></date></history><permissions><copyright-statement>Copyright © 2016, International Bone & Mineral Society</copyright-statement><copyright-year>2016</copyright-year><copyright-holder>International Bone & Mineral Society</copyright-holder></permissions><abstract><p>Curcumin is the active component of turmeric extract derived from the Curcuma longa plant. In the last decade, curcumin has raised a considerable interest in medicine owing to its negligible toxicity and multiple therapeutic actions including anti-cancer, anti-inflammatory and anti-microbial activities. Among the various molecular targets of curcumin, some are involved in bone remodeling, which strongly suggests that curcumin can affect the skeletal system. The review sheds light on the current and potential applications of curcumin to treat bone disorders characterized by an excessive resorption activity. Within the scope of this review, the novel formulations of curcumin to overcome its physico-chemical and pharmacokinetic constraints are also discussed.</p></abstract></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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