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<title xml:lang="en">Infectious diseases in oyster aquaculture require a new integrated approach</title>
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<name sortKey="Pernet, Fabrice" sort="Pernet, Fabrice" uniqKey="Pernet F" first="Fabrice" last="Pernet">Fabrice Pernet</name>
<affiliation>
<nlm:aff id="af1">
<addr-line>UMR LEMAR 6539 (UBO/CNRS/IRD/Ifremer)</addr-line>
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<institution>Ifremer</institution>
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<addr-line>Technopôle Brest Iroise, BP 70, Plouzané 29280</addr-line>
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<country>France</country>
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</affiliation>
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<author>
<name sortKey="Lupo, Coralie" sort="Lupo, Coralie" uniqKey="Lupo C" first="Coralie" last="Lupo">Coralie Lupo</name>
<affiliation>
<nlm:aff id="af3">
<addr-line>Laboratoire de Génétique et Pathologie des Mollusques Marins</addr-line>
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<institution>Ifremer—SG2M-LGPMM</institution>
,
<addr-line>Avenue Mus de Loup, La Tremblade 17390</addr-line>
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<country>France</country>
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<name sortKey="Bacher, Cedric" sort="Bacher, Cedric" uniqKey="Bacher C" first="Cédric" last="Bacher">Cédric Bacher</name>
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<addr-line>Dyneco/BENTHOS</addr-line>
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<institution>Ifremer</institution>
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<addr-line>Technopôle Brest Iroise, BP 70, Plouzané 29280</addr-line>
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<country>France</country>
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<name sortKey="Whittington, Richard J" sort="Whittington, Richard J" uniqKey="Whittington R" first="Richard J." last="Whittington">Richard J. Whittington</name>
<affiliation>
<nlm:aff id="af4">
<addr-line>Faculty of Veterinary Science</addr-line>
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<institution>The University of Sydney</institution>
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<addr-line>425 Werombi Road, Camden, New South Wales 2570</addr-line>
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<country>Australia</country>
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<title xml:lang="en" level="a" type="main">Infectious diseases in oyster aquaculture require a new integrated approach</title>
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<name sortKey="Pernet, Fabrice" sort="Pernet, Fabrice" uniqKey="Pernet F" first="Fabrice" last="Pernet">Fabrice Pernet</name>
<affiliation>
<nlm:aff id="af1">
<addr-line>UMR LEMAR 6539 (UBO/CNRS/IRD/Ifremer)</addr-line>
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<institution>Ifremer</institution>
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<addr-line>Technopôle Brest Iroise, BP 70, Plouzané 29280</addr-line>
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<country>France</country>
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</affiliation>
</author>
<author>
<name sortKey="Lupo, Coralie" sort="Lupo, Coralie" uniqKey="Lupo C" first="Coralie" last="Lupo">Coralie Lupo</name>
<affiliation>
<nlm:aff id="af3">
<addr-line>Laboratoire de Génétique et Pathologie des Mollusques Marins</addr-line>
,
<institution>Ifremer—SG2M-LGPMM</institution>
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<addr-line>Avenue Mus de Loup, La Tremblade 17390</addr-line>
,
<country>France</country>
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</affiliation>
</author>
<author>
<name sortKey="Bacher, Cedric" sort="Bacher, Cedric" uniqKey="Bacher C" first="Cédric" last="Bacher">Cédric Bacher</name>
<affiliation>
<nlm:aff id="af2">
<addr-line>Dyneco/BENTHOS</addr-line>
,
<institution>Ifremer</institution>
,
<addr-line>Technopôle Brest Iroise, BP 70, Plouzané 29280</addr-line>
,
<country>France</country>
</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Whittington, Richard J" sort="Whittington, Richard J" uniqKey="Whittington R" first="Richard J." last="Whittington">Richard J. Whittington</name>
<affiliation>
<nlm:aff id="af4">
<addr-line>Faculty of Veterinary Science</addr-line>
,
<institution>The University of Sydney</institution>
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<addr-line>425 Werombi Road, Camden, New South Wales 2570</addr-line>
,
<country>Australia</country>
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<title level="j">Philosophical Transactions of the Royal Society B: Biological Sciences</title>
<idno type="ISSN">0962-8436</idno>
<idno type="eISSN">1471-2970</idno>
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<p>Emerging diseases pose a recurrent threat to bivalve aquaculture. Recently, massive mortality events in the Pacific oyster
<italic>Crassostrea gigas</italic>
associated with the detection of a microvariant of the ostreid herpesvirus 1 (OsHV-1µVar) have been reported in Europe, Australia and New Zealand. Although the spread of disease is often viewed as a governance failure, we suggest that the development of protective measures for bivalve farming is presently held back by the lack of key scientific knowledge. In this paper, we explore the case for an integrated approach to study the management of bivalve disease, using OsHV-1 as a case study. Reconsidering the key issues by incorporating multidisciplinary science could provide a holistic understanding of OsHV-1 and increase the benefit of research to policymakers.</p>
</div>
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<journal-id journal-id-type="nlm-ta">Philos Trans R Soc Lond B Biol Sci</journal-id>
<journal-id journal-id-type="iso-abbrev">Philos. Trans. R. Soc. Lond., B, Biol. Sci</journal-id>
<journal-id journal-id-type="publisher-id">RSTB</journal-id>
<journal-id journal-id-type="hwp">royptb</journal-id>
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<journal-title>Philosophical Transactions of the Royal Society B: Biological Sciences</journal-title>
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<issn pub-type="ppub">0962-8436</issn>
<issn pub-type="epub">1471-2970</issn>
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<publisher-name>The Royal Society</publisher-name>
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<article-id pub-id-type="publisher-id">rstb20150213</article-id>
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<subject>60</subject>
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<subj-group subj-group-type="heading">
<subject>Articles</subject>
</subj-group>
<subj-group subj-group-type="leader">
<subject>Opinion Piece</subject>
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</article-categories>
<title-group>
<article-title>Infectious diseases in oyster aquaculture require a new integrated approach</article-title>
<alt-title alt-title-type="short">disease management of oyster</alt-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<contrib-id contrib-id-type="orcid" authenticated="false">http://orcid.org/0000-0001-8886-0184</contrib-id>
<name>
<surname>Pernet</surname>
<given-names>Fabrice</given-names>
</name>
<xref ref-type="aff" rid="af1">1</xref>
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</contrib>
<contrib contrib-type="author">
<name>
<surname>Lupo</surname>
<given-names>Coralie</given-names>
</name>
<xref ref-type="aff" rid="af3">3</xref>
</contrib>
<contrib contrib-type="author">
<contrib-id contrib-id-type="orcid" authenticated="false">http://orcid.org/0000-0001-6090-4667</contrib-id>
<name>
<surname>Bacher</surname>
<given-names>Cédric</given-names>
</name>
<xref ref-type="aff" rid="af2">2</xref>
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<contrib contrib-type="author">
<name>
<surname>Whittington</surname>
<given-names>Richard J.</given-names>
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<xref ref-type="aff" rid="af4">4</xref>
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<aff id="af1">
<label>1</label>
<addr-line>UMR LEMAR 6539 (UBO/CNRS/IRD/Ifremer)</addr-line>
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<institution>Ifremer</institution>
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<addr-line>Technopôle Brest Iroise, BP 70, Plouzané 29280</addr-line>
,
<country>France</country>
</aff>
<aff id="af2">
<label>2</label>
<addr-line>Dyneco/BENTHOS</addr-line>
,
<institution>Ifremer</institution>
,
<addr-line>Technopôle Brest Iroise, BP 70, Plouzané 29280</addr-line>
,
<country>France</country>
</aff>
<aff id="af3">
<label>3</label>
<addr-line>Laboratoire de Génétique et Pathologie des Mollusques Marins</addr-line>
,
<institution>Ifremer—SG2M-LGPMM</institution>
,
<addr-line>Avenue Mus de Loup, La Tremblade 17390</addr-line>
,
<country>France</country>
</aff>
<aff id="af4">
<label>4</label>
<addr-line>Faculty of Veterinary Science</addr-line>
,
<institution>The University of Sydney</institution>
,
<addr-line>425 Werombi Road, Camden, New South Wales 2570</addr-line>
,
<country>Australia</country>
</aff>
<author-notes>
<corresp id="cor1">e-mail:
<email>fabrice.pernet@ifremer.fr</email>
</corresp>
<fn fn-type="other">
<p>One contribution of 14 to a theme issue ‘
<ext-link ext-link-type="uri" xlink:href="http://rstb.royalsocietypublishing.org/content/371/1689.toc">Marine disease</ext-link>
’.</p>
</fn>
</author-notes>
<pub-date pub-type="ppub">
<day>5</day>
<month>3</month>
<year>2016</year>
</pub-date>
<volume>371</volume>
<issue>1689</issue>
<issue-title>Theme issue ‘Marine disease’ compiled and edited by Kevin D. Lafferty and Eileen E. Hofmann</issue-title>
<elocation-id>20150213</elocation-id>
<history>
<date date-type="accepted">
<day>16</day>
<month>12</month>
<year>2015</year>
</date>
</history>
<permissions>
<copyright-statement>© 2016 The Author(s)</copyright-statement>
<copyright-year>2016</copyright-year>
<license specific-use="vor" xlink:href="http://royalsocietypublishing.org/licence">
<license-p>Published by the Royal Society. All rights reserved.</license-p>
</license>
</permissions>
<self-uri content-type="pdf" xlink:href="rstb20150213.pdf"></self-uri>
<abstract>
<p>Emerging diseases pose a recurrent threat to bivalve aquaculture. Recently, massive mortality events in the Pacific oyster
<italic>Crassostrea gigas</italic>
associated with the detection of a microvariant of the ostreid herpesvirus 1 (OsHV-1µVar) have been reported in Europe, Australia and New Zealand. Although the spread of disease is often viewed as a governance failure, we suggest that the development of protective measures for bivalve farming is presently held back by the lack of key scientific knowledge. In this paper, we explore the case for an integrated approach to study the management of bivalve disease, using OsHV-1 as a case study. Reconsidering the key issues by incorporating multidisciplinary science could provide a holistic understanding of OsHV-1 and increase the benefit of research to policymakers.</p>
</abstract>
<kwd-group>
<kwd>bivalve</kwd>
<kwd>disease management</kwd>
<kwd>epidemiology</kwd>
<kwd>multidisciplinary</kwd>
<kwd>risk</kwd>
</kwd-group>
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<institution-wrap>
<institution>Agence Nationale de la Recherche</institution>
<institution-id>http://dx.doi.org/10.13039/501100001665</institution-id>
</institution-wrap>
</funding-source>
<award-id>ANR-10-LABX-19</award-id>
<award-id>ANR-12-AGRO-0001-01</award-id>
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<funding-group specific-use="FundRef">
<award-group>
<funding-source>
<institution-wrap>
<institution>Fisheries Research and Development Corporation</institution>
<institution-id>http://dx.doi.org/10.13039/501100000979</institution-id>
</institution-wrap>
</funding-source>
<award-id>2014-040</award-id>
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<custom-meta-group>
<custom-meta>
<meta-name>cover-date</meta-name>
<meta-value>March 5, 2016</meta-value>
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</front>
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