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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Genetically predicted longer telomere length is associated with increased risk of B-cell lymphoma subtypes</title><author><name sortKey="Machiela, Mitchell J" sort="Machiela, Mitchell J" uniqKey="Machiela M" first="Mitchell J." last="Machiela">Mitchell J. Machiela</name><affiliation><nlm:aff id="af1"><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Bethesda, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Lan, Qing" sort="Lan, Qing" uniqKey="Lan Q" first="Qing" last="Lan">Qing Lan</name><affiliation><nlm:aff id="af1"><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Bethesda, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Slager, Susan L" sort="Slager, Susan L" uniqKey="Slager S" first="Susan L." last="Slager">Susan L. Slager</name><affiliation><nlm:aff id="af2"><addr-line>Department of Health Sciences Research</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Vermeulen, Roel C H" sort="Vermeulen, Roel C H" uniqKey="Vermeulen R" first="Roel C. H." last="Vermeulen">Roel C. H. Vermeulen</name><affiliation><nlm:aff id="af5"><addr-line>Institute for Risk Assessment Sciences</addr-line>,<institution>Utrecht University</institution>,<addr-line>Utrecht</addr-line>,<institution>The Netherlands</institution>,</nlm:aff></affiliation><affiliation><nlm:aff wicri:cut=" and" id="af6"><addr-line>Julius Center for Health Sciences and Primary Care</addr-line></nlm:aff></affiliation></author><author><name sortKey="Teras, Lauren R" sort="Teras, Lauren R" uniqKey="Teras L" first="Lauren R." last="Teras">Lauren R. Teras</name><affiliation><nlm:aff id="af8"><addr-line>Epidemiology Research Program</addr-line>,<institution>American Cancer Society</institution>,<addr-line>Atlanta, GA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Camp, Nicola J" sort="Camp, Nicola J" uniqKey="Camp N" first="Nicola J." last="Camp">Nicola J. Camp</name><affiliation><nlm:aff id="af9"><addr-line>Department of Internal Medicine</addr-line>,<institution>University of Utah School of Medicine</institution>,<addr-line>Salt Lake City, UT</addr-line>,<institution>USA</institution>,</nlm:aff></affiliation></author><author><name sortKey="Cerhan, James R" sort="Cerhan, James R" uniqKey="Cerhan J" first="James R." last="Cerhan">James R. Cerhan</name><affiliation><nlm:aff id="af2"><addr-line>Department of Health Sciences Research</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Spinelli, John J" sort="Spinelli, John J" uniqKey="Spinelli J" first="John J." last="Spinelli">John J. Spinelli</name><affiliation><nlm:aff wicri:cut=" and" id="af10"><addr-line>Cancer Control Research</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af12"><addr-line>School of Population and Public Health</addr-line>,<institution>University of British Columbia</institution>,<addr-line>Vancouver, BC</addr-line>,<country>Canada</country>,</nlm:aff></affiliation></author><author><name sortKey="Wang, Sophia S" sort="Wang, Sophia S" uniqKey="Wang S" first="Sophia S." last="Wang">Sophia S. Wang</name><affiliation><nlm:aff id="af13"><addr-line>Division of Cancer Etiology</addr-line>,<institution>City of Hope Beckman Research Institute</institution>,<addr-line>Duarte, CA</addr-line>,<institution>USA</institution>,</nlm:aff></affiliation></author><author><name sortKey="Nieters, Alexandra" sort="Nieters, Alexandra" uniqKey="Nieters A" first="Alexandra" last="Nieters">Alexandra Nieters</name><affiliation><nlm:aff id="af14"><addr-line>Center for Chronic Immunodeficiency</addr-line>,<institution>University Medical Center Freiburg</institution>,<addr-line>Freiburg, Baden-Württemberg</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Vijai, Joseph" sort="Vijai, Joseph" uniqKey="Vijai J" first="Joseph" last="Vijai">Joseph Vijai</name><affiliation><nlm:aff wicri:cut=" and" id="af15"><addr-line>Department of Medicine</addr-line></nlm:aff></affiliation></author><author><name sortKey="Yeager, Meredith" sort="Yeager, Meredith" uniqKey="Yeager M" first="Meredith" last="Yeager">Meredith Yeager</name><affiliation><nlm:aff id="af17"><addr-line>Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Gaithersburg, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Wang, Zhaoming" sort="Wang, Zhaoming" uniqKey="Wang Z" first="Zhaoming" last="Wang">Zhaoming Wang</name><affiliation><nlm:aff id="af17"><addr-line>Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Gaithersburg, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Ghesquieres, Herve" sort="Ghesquieres, Herve" uniqKey="Ghesquieres H" first="Hervé" last="Ghesquières">Hervé Ghesquières</name><affiliation><nlm:aff wicri:cut=" and" id="af18"><addr-line>Department of Hematology</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af20"><addr-line>Laboratoire de Biologie Moléculaire de la Cellule UMR 5239</addr-line>,<institution>Centre National de la Recherche Scientifique</institution>,<addr-line>Pierre benite Cedex</addr-line>,<institution>France</institution>,</nlm:aff></affiliation></author><author><name sortKey="Mckay, James" sort="Mckay, James" uniqKey="Mckay J" first="James" last="Mckay">James Mckay</name><affiliation><nlm:aff id="af21"><institution>International Agency for Research on Cancer (IARC)</institution>,<addr-line>Lyon</addr-line>,<country>France</country>,</nlm:aff></affiliation></author><author><name sortKey="Conde, Lucia" sort="Conde, Lucia" uniqKey="Conde L" first="Lucia" last="Conde">Lucia Conde</name><affiliation><nlm:aff wicri:cut=" and" id="af22"><addr-line>Department of Epidemiology, School of Public Health and Comprehensive Cancer Center</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af24"><addr-line>Division of Environmental Health Sciences</addr-line>,<institution>University of California Berkeley School of Public Health</institution>,<addr-line>Berkeley, CA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="De Bakker, Paul I W" sort="De Bakker, Paul I W" uniqKey="De Bakker P" first="Paul I. W." last="De Bakker">Paul I. W. De Bakker</name><affiliation><nlm:aff wicri:cut=" and" id="af6"><addr-line>Julius Center for Health Sciences and Primary Care</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af7"><addr-line>Department of Medical Genetics and of Epidemiology</addr-line>,<institution>University Medical Center Utrecht</institution>,<addr-line>Utrecht</addr-line>,<country>The Netherlands</country>,</nlm:aff></affiliation></author><author><name sortKey="Cox, David G" sort="Cox, David G" uniqKey="Cox D" first="David G." last="Cox">David G. Cox</name><affiliation><nlm:aff id="af19"><addr-line>INSERM U1052, Cancer Research Center of Lyon</addr-line>,<institution>Centre Léon Bérard</institution>,<addr-line>Lyon</addr-line>,<country>France</country>,</nlm:aff></affiliation></author><author><name sortKey="Burdett, Laurie" sort="Burdett, Laurie" uniqKey="Burdett L" first="Laurie" last="Burdett">Laurie Burdett</name><affiliation><nlm:aff id="af17"><addr-line>Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Gaithersburg, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Monnereau, Alain" sort="Monnereau, Alain" uniqKey="Monnereau A" first="Alain" last="Monnereau">Alain Monnereau</name><affiliation><nlm:aff id="af25"><addr-line>Epidemiology of Childhood and Adolescent Cancers Group, INSERM</addr-line>,<institution>Center of Research in Epidemiology and Statistics Sorbonne Paris Cité (CRESS)</institution>,<addr-line>Paris</addr-line>,<country>France</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af26"><institution>Université Paris Descartes</institution>,<addr-line>Paris</addr-line>,<country>France</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af27"><addr-line>Registre des hémopathies malignes de la Gironde</addr-line>,<institution>Institut Bergonié</institution>,<addr-line>Bordeaux Cedex</addr-line>,<institution>France</institution>,</nlm:aff></affiliation></author><author><name sortKey="Flowers, Christopher R" sort="Flowers, Christopher R" uniqKey="Flowers C" first="Christopher R." last="Flowers">Christopher R. Flowers</name><affiliation><nlm:aff id="af28"><addr-line>Winship Cancer Institute</addr-line>,<institution>Emory University School of Medicine</institution>,<addr-line>Atlanta, GA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="De Roos, Anneclaire J" sort="De Roos, Anneclaire J" uniqKey="De Roos A" first="Anneclaire J." last="De Roos">Anneclaire J. De Roos</name><affiliation><nlm:aff id="af29"><addr-line>Department of Environmental and Occupational Health</addr-line>,<institution>Drexel University School of Public Health</institution>,<addr-line>Philadelphia, PA</addr-line>,<country>USA</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af30"><addr-line>Division of Public Health Sciences</addr-line>,<institution>Fred Hutchinson Cancer Research Center</institution>,<addr-line>Seattle, WA</addr-line>,<institution>USA</institution>,</nlm:aff></affiliation></author><author><name sortKey="Brooks Wilson, Angela R" sort="Brooks Wilson, Angela R" uniqKey="Brooks Wilson A" first="Angela R." last="Brooks-Wilson">Angela R. Brooks-Wilson</name><affiliation><nlm:aff id="af11"><addr-line>Genome Sciences Centre</addr-line>,<institution>BC Cancer Agency</institution>,<addr-line>Vancouver, BC</addr-line>,<country>Canada</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af31"><addr-line>Department of Biomedical Physiology and Kinesiology</addr-line>,<institution>Simon Fraser University</institution>,<addr-line>Burnaby, BC</addr-line>,<institution>Canada</institution>,</nlm:aff></affiliation></author><author><name sortKey="Giles, Graham G" sort="Giles, Graham G" uniqKey="Giles G" first="Graham G." last="Giles">Graham G. Giles</name><affiliation><nlm:aff id="af32"><addr-line>Cancer Epidemiology Centre</addr-line>,<institution>Cancer Council Victoria</institution>,<addr-line>Melbourne, VIC</addr-line>,<institution>Australia</institution>,</nlm:aff></affiliation><affiliation><nlm:aff wicri:cut=" and" id="af33"><addr-line>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health</addr-line></nlm:aff></affiliation></author><author><name sortKey="Melbye, Mads" sort="Melbye, Mads" uniqKey="Melbye M" first="Mads" last="Melbye">Mads Melbye</name><affiliation><nlm:aff id="af35"><addr-line>Department of Epidemiology Research, Division of Health Surveillance and Research</addr-line>,<institution>Statens Serum Institut</institution>,<addr-line>Copenhagen</addr-line>,<country>Denmark</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af36"><addr-line>Department of Medicine</addr-line>,<institution>Stanford University School of Medicine</institution>,<addr-line>Stanford, CA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Gu, Jian" sort="Gu, Jian" uniqKey="Gu J" first="Jian" last="Gu">Jian Gu</name><affiliation><nlm:aff id="af37"><addr-line>Department of Epidemiology</addr-line>,<institution>MD Anderson Cancer Center</institution>,<addr-line>Houston, TX</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Jackson, Rebecca D" sort="Jackson, Rebecca D" uniqKey="Jackson R" first="Rebecca D." last="Jackson">Rebecca D. Jackson</name><affiliation><nlm:aff id="af38"><addr-line>Division of Endocrinology, Diabetes and Metabolism</addr-line>,<institution>The Ohio State University</institution>,<addr-line>Columbus, OH</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Kane, Eleanor" sort="Kane, Eleanor" uniqKey="Kane E" first="Eleanor" last="Kane">Eleanor Kane</name><affiliation><nlm:aff id="af39"><addr-line>Department of Health Sciences</addr-line>,<institution>University of York</institution>,<addr-line>York</addr-line>,<country>UK</country>,</nlm:aff></affiliation></author><author><name sortKey="Purdue, Mark P" sort="Purdue, Mark P" uniqKey="Purdue M" first="Mark P." last="Purdue">Mark P. Purdue</name><affiliation><nlm:aff id="af40"><addr-line>Ontario Health Study, Toronto, ON</addr-line>,<institution>Canada</institution>,</nlm:aff></affiliation></author><author><name sortKey="Vajdic, Claire M" sort="Vajdic, Claire M" uniqKey="Vajdic C" first="Claire M." last="Vajdic">Claire M. Vajdic</name><affiliation><nlm:aff id="af41"><addr-line>Centre for Big Data Research in Health</addr-line>,<institution>University of New South Wales</institution>,<addr-line>Sydney, NSW</addr-line>,<country>Australia</country>,</nlm:aff></affiliation></author><author><name sortKey="Albanes, Demetrius" sort="Albanes, Demetrius" uniqKey="Albanes D" first="Demetrius" last="Albanes">Demetrius Albanes</name><affiliation><nlm:aff id="af1"><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Bethesda, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Kelly, Rachel S" sort="Kelly, Rachel S" uniqKey="Kelly R" first="Rachel S." last="Kelly">Rachel S. Kelly</name><affiliation><nlm:aff id="af42"><addr-line>Department of Epidemiology</addr-line>,</nlm:aff></affiliation><affiliation><nlm:aff wicri:cut=" and" id="af45"><addr-line>MRC-PHE Centre for Environment and Health, School of Public Health</addr-line></nlm:aff></affiliation></author><author><name sortKey="Zucca, Mariagrazia" sort="Zucca, Mariagrazia" uniqKey="Zucca M" first="Mariagrazia" last="Zucca">Mariagrazia Zucca</name><affiliation><nlm:aff wicri:cut=" and" id="af47"><addr-line>Department of Biomedical Science</addr-line></nlm:aff></affiliation></author><author><name sortKey="Bertrand, Kimberly A" sort="Bertrand, Kimberly A" uniqKey="Bertrand K" first="Kimberly A." last="Bertrand">Kimberly A. Bertrand</name><affiliation><nlm:aff id="af42"><addr-line>Department of Epidemiology</addr-line>,</nlm:aff></affiliation><affiliation><nlm:aff id="af49"><addr-line>Channing Division of Network Medicine, Department of Medicine</addr-line>,<institution>Brigham and Women's Hospital and Harvard Medical School</institution>,<addr-line>Boston, MA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Zeleniuch Jacquotte, Anne" sort="Zeleniuch Jacquotte, Anne" uniqKey="Zeleniuch Jacquotte A" first="Anne" last="Zeleniuch-Jacquotte">Anne Zeleniuch-Jacquotte</name><affiliation><nlm:aff wicri:cut=" and" id="af50"><addr-line>Department of Population Health</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af51"><addr-line>Department of Environmental Medicine</addr-line>,<institution>New York University School of Medicine</institution>,<addr-line>New York, NY</addr-line>,<institution>USA</institution>,</nlm:aff></affiliation><affiliation><nlm:aff id="af52"><addr-line>Perlmutter Cancer Center</addr-line>,<institution>NYU Langone Medical Center</institution>,<addr-line>New York, NY</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Lawrence, Charles" sort="Lawrence, Charles" uniqKey="Lawrence C" first="Charles" last="Lawrence">Charles Lawrence</name><affiliation><nlm:aff id="af53"><institution>Westat</institution>,<addr-line>Rockville, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Hutchinson, Amy" sort="Hutchinson, Amy" uniqKey="Hutchinson A" first="Amy" last="Hutchinson">Amy Hutchinson</name><affiliation><nlm:aff id="af17"><addr-line>Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Gaithersburg, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Zhi, Degui" sort="Zhi, Degui" uniqKey="Zhi D" first="Degui" last="Zhi">Degui Zhi</name><affiliation><nlm:aff id="af23"><addr-line>Department of Biostatistics</addr-line>,<institution>University of Alabama at Birmingham</institution>,<addr-line>Birmingham, AL</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Habermann, Thomas M" sort="Habermann, Thomas M" uniqKey="Habermann T" first="Thomas M." last="Habermann">Thomas M. Habermann</name><affiliation><nlm:aff wicri:cut=" and" id="af3"><addr-line>Department of Medicine</addr-line></nlm:aff></affiliation></author><author><name sortKey="Link, Brian K" sort="Link, Brian K" uniqKey="Link B" first="Brian K." last="Link">Brian K. Link</name><affiliation><nlm:aff id="af54"><addr-line>Department of Internal Medicine, Carver College of Medicine</addr-line>,<institution>The University of Iowa</institution>,<addr-line>Iowa City, IA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Novak, Anne J" sort="Novak, Anne J" uniqKey="Novak A" first="Anne J." last="Novak">Anne J. Novak</name><affiliation><nlm:aff wicri:cut=" and" id="af3"><addr-line>Department of Medicine</addr-line></nlm:aff></affiliation></author><author><name sortKey="Dogan, Ahmet" sort="Dogan, Ahmet" uniqKey="Dogan A" first="Ahmet" last="Dogan">Ahmet Dogan</name><affiliation><nlm:aff id="af16"><addr-line>Departments of Laboratory Medicine and Pathology</addr-line>,<institution>Memorial Sloan Kettering Cancer Center</institution>,<addr-line>New York, NY</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Asmann, Yan W" sort="Asmann, Yan W" uniqKey="Asmann Y" first="Yan W." last="Asmann">Yan W. Asmann</name><affiliation><nlm:aff id="af4"><addr-line>Division of Biomedical Statistics and Informatics, Department of Health Sciences Research</addr-line>,<institution>Mayo Clinic</institution>,<addr-line>Rochester, MN</addr-line>,<institution>USA</institution>,</nlm:aff></affiliation></author><author><name sortKey="Liebow, Mark" sort="Liebow, Mark" uniqKey="Liebow M" first="Mark" last="Liebow">Mark Liebow</name><affiliation><nlm:aff wicri:cut=" and" id="af3"><addr-line>Department of Medicine</addr-line></nlm:aff></affiliation></author><author><name sortKey="Thompson, Carrie A" sort="Thompson, Carrie A" uniqKey="Thompson C" first="Carrie A." last="Thompson">Carrie A. Thompson</name><affiliation><nlm:aff wicri:cut=" and" id="af3"><addr-line>Department of Medicine</addr-line></nlm:aff></affiliation></author><author><name sortKey="Ansell, Stephen M" sort="Ansell, Stephen M" uniqKey="Ansell S" first="Stephen M." last="Ansell">Stephen M. Ansell</name><affiliation><nlm:aff wicri:cut=" and" id="af3"><addr-line>Department of Medicine</addr-line></nlm:aff></affiliation></author><author><name sortKey="Witzig, Thomas E" sort="Witzig, Thomas E" uniqKey="Witzig T" first="Thomas E." last="Witzig">Thomas E. Witzig</name><affiliation><nlm:aff wicri:cut=" and" id="af3"><addr-line>Department of Medicine</addr-line></nlm:aff></affiliation></author><author><name sortKey="Tilly, Herve" sort="Tilly, Herve" uniqKey="Tilly H" first="Hervé" last="Tilly">Hervé Tilly</name><affiliation><nlm:aff id="af55"><addr-line>Centre Heni Becquerel</addr-line>,<institution>Université de Rouen</institution>,<addr-line>Rouen</addr-line>,<country>France</country>,</nlm:aff></affiliation></author><author><name sortKey="Haioun, Corinne" sort="Haioun, Corinne" uniqKey="Haioun C" first="Corinne" last="Haioun">Corinne Haioun</name><affiliation><nlm:aff id="af56"><addr-line>Lymphoid Malignancies Unit</addr-line>,<institution>Henri Mondor Hospital and University Paris Est</institution>,<addr-line>Créteil</addr-line>,<country>France</country>,</nlm:aff></affiliation></author><author><name sortKey="Molina, Thierry J" sort="Molina, Thierry J" uniqKey="Molina T" first="Thierry J." last="Molina">Thierry J. Molina</name><affiliation><nlm:aff id="af57"><addr-line>Department of Pathology, AP-HP, Necker Enfants malades</addr-line>,<institution>Université Paris Descartes</institution>,<addr-line>Sorbonne Paris Cité</addr-line>,<country>France</country>,</nlm:aff></affiliation></author><author><name sortKey="Hjalgrim, Henrik" sort="Hjalgrim, Henrik" uniqKey="Hjalgrim H" first="Henrik" last="Hjalgrim">Henrik Hjalgrim</name><affiliation><nlm:aff id="af35"><addr-line>Department of Epidemiology Research, Division of Health Surveillance and Research</addr-line>,<institution>Statens Serum Institut</institution>,<addr-line>Copenhagen</addr-line>,<country>Denmark</country>,</nlm:aff></affiliation></author><author><name sortKey="Glimelius, Bengt" sort="Glimelius, Bengt" uniqKey="Glimelius B" first="Bengt" last="Glimelius">Bengt Glimelius</name><affiliation><nlm:aff id="af58"><addr-line>Department of Immunology, Genetics and Pathology</addr-line>,<institution>Uppsala University</institution>,<addr-line>Uppsala</addr-line>,<country>Sweden</country>,</nlm:aff></affiliation></author><author><name sortKey="Adami, Hans Olov" sort="Adami, Hans Olov" uniqKey="Adami H" first="Hans-Olov" last="Adami">Hans-Olov Adami</name><affiliation><nlm:aff id="af42"><addr-line>Department of Epidemiology</addr-line>,</nlm:aff></affiliation><affiliation><nlm:aff id="af59"><addr-line>Department of Medical Epidemiology and Biostatistics</addr-line>,<institution>Karolinska Institutet</institution>,<addr-line>Stockholm</addr-line>,<country>Sweden</country>,</nlm:aff></affiliation></author><author><name sortKey="Roos, Goran" sort="Roos, Goran" uniqKey="Roos G" first="Göran" last="Roos">Göran Roos</name><affiliation><nlm:aff id="af60"><addr-line>Department of Medical Biosciences</addr-line>,<institution>Umeå University</institution>,<addr-line>Umeå</addr-line>,<country>Sweden</country>,</nlm:aff></affiliation></author><author><name sortKey="Bracci, Paige M" sort="Bracci, Paige M" uniqKey="Bracci P" first="Paige M." last="Bracci">Paige M. Bracci</name><affiliation><nlm:aff id="af61"><addr-line>Department of Epidemiology and Biostatistics</addr-line>,<institution>University of California San Francisco</institution>,<addr-line>San Francisco, CA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Riby, Jacques" sort="Riby, Jacques" uniqKey="Riby J" first="Jacques" last="Riby">Jacques Riby</name><affiliation><nlm:aff wicri:cut=" and" id="af22"><addr-line>Department of Epidemiology, School of Public Health and Comprehensive Cancer Center</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af24"><addr-line>Division of Environmental Health Sciences</addr-line>,<institution>University of California Berkeley School of Public Health</institution>,<addr-line>Berkeley, CA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Smith, Martyn T" sort="Smith, Martyn T" uniqKey="Smith M" first="Martyn T." last="Smith">Martyn T. Smith</name><affiliation><nlm:aff id="af24"><addr-line>Division of Environmental Health Sciences</addr-line>,<institution>University of California Berkeley School of Public Health</institution>,<addr-line>Berkeley, CA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Holly, Elizabeth A" sort="Holly, Elizabeth A" uniqKey="Holly E" first="Elizabeth A." last="Holly">Elizabeth A. Holly</name><affiliation><nlm:aff id="af61"><addr-line>Department of Epidemiology and Biostatistics</addr-line>,<institution>University of California San Francisco</institution>,<addr-line>San Francisco, CA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Cozen, Wendy" sort="Cozen, Wendy" uniqKey="Cozen W" first="Wendy" last="Cozen">Wendy Cozen</name><affiliation><nlm:aff wicri:cut=" and" id="af62"><addr-line>Department of Preventive Medicine</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af63"><addr-line>Norris Comprehensive Cancer Center, USC Keck School of Medicine</addr-line>,<institution>University of Southern California</institution>,<addr-line>Los Angeles, CA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Hartge, Patricia" sort="Hartge, Patricia" uniqKey="Hartge P" first="Patricia" last="Hartge">Patricia Hartge</name><affiliation><nlm:aff id="af1"><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Bethesda, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Morton, Lindsay M" sort="Morton, Lindsay M" uniqKey="Morton L" first="Lindsay M." last="Morton">Lindsay M. Morton</name><affiliation><nlm:aff id="af1"><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Bethesda, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Severson, Richard K" sort="Severson, Richard K" uniqKey="Severson R" first="Richard K." last="Severson">Richard K. Severson</name><affiliation><nlm:aff id="af64"><addr-line>Department of Family Medicine and Public Health Sciences</addr-line>,<institution>Wayne State University</institution>,<addr-line>Detroit, MI</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Tinker, Lesley F" sort="Tinker, Lesley F" uniqKey="Tinker L" first="Lesley F." last="Tinker">Lesley F. Tinker</name><affiliation><nlm:aff id="af30"><addr-line>Division of Public Health Sciences</addr-line>,<institution>Fred Hutchinson Cancer Research Center</institution>,<addr-line>Seattle, WA</addr-line>,<institution>USA</institution>,</nlm:aff></affiliation></author><author><name sortKey="North, Kari E" sort="North, Kari E" uniqKey="North K" first="Kari E." last="North">Kari E. North</name><affiliation><nlm:aff wicri:cut=" and" id="af65"><addr-line>Department of Epidemiology</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af66"><addr-line>Carolina Center for Genome Sciences</addr-line>,<institution>University of North Carolina at Chapel Hill</institution>,<addr-line>Chapel Hill, NC</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Becker, Nikolaus" sort="Becker, Nikolaus" uniqKey="Becker N" first="Nikolaus" last="Becker">Nikolaus Becker</name><affiliation><nlm:aff id="af67"><addr-line>Division of Cancer Epidemiology</addr-line>,<institution>German Cancer Research Center (DKFZ)</institution>,<addr-line>Heidelberg, Baden-Württemberg</addr-line>,<institution>Germany</institution>,</nlm:aff></affiliation></author><author><name sortKey="Benavente, Yolanda" sort="Benavente, Yolanda" uniqKey="Benavente Y" first="Yolanda" last="Benavente">Yolanda Benavente</name><affiliation><nlm:aff id="af68"><addr-line>Cancer Epidemiology Research Programme, Catalan Institute of Oncology-IDIBELL</addr-line>,<institution>L'Hospitalet de Llobregat</institution>,<addr-line>Barcelona</addr-line>,<country>Spain</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af69"><institution>CIBER de Epidemiología y Salud Pública (CIBERESP)</institution>,<addr-line>Barcelona</addr-line>,<institution>Spain</institution>,</nlm:aff></affiliation></author><author><name sortKey="Boffetta, Paolo" sort="Boffetta, Paolo" uniqKey="Boffetta P" first="Paolo" last="Boffetta">Paolo Boffetta</name><affiliation><nlm:aff wicri:cut=" and" id="af70"><addr-line>The Tisch Cancer Institute</addr-line></nlm:aff></affiliation></author><author><name sortKey="Brennan, Paul" sort="Brennan, Paul" uniqKey="Brennan P" first="Paul" last="Brennan">Paul Brennan</name><affiliation><nlm:aff id="af21"><institution>International Agency for Research on Cancer (IARC)</institution>,<addr-line>Lyon</addr-line>,<country>France</country>,</nlm:aff></affiliation></author><author><name sortKey="Foretova, Lenka" sort="Foretova, Lenka" uniqKey="Foretova L" first="Lenka" last="Foretova">Lenka Foretova</name><affiliation><nlm:aff id="af72"><addr-line>Department of Cancer Epidemiology and Genetics</addr-line>,<institution>Masaryk Memorial Cancer Institute and MF MU</institution>,<addr-line>Brno</addr-line>,<country>Czech Republic</country>,</nlm:aff></affiliation></author><author><name sortKey="Maynadie, Marc" sort="Maynadie, Marc" uniqKey="Maynadie M" first="Marc" last="Maynadie">Marc Maynadie</name><affiliation><nlm:aff id="af73"><addr-line>EA 4184, Registre des Hémopathies Malignes de Côte d'Or</addr-line>,<institution>University of Burgundy and Dijon University Hospital</institution>,<addr-line>Dijon</addr-line>,<country>France</country>,</nlm:aff></affiliation></author><author><name sortKey="Staines, Anthony" sort="Staines, Anthony" uniqKey="Staines A" first="Anthony" last="Staines">Anthony Staines</name><affiliation><nlm:aff id="af74"><addr-line>School of Nursing and Human Sciences</addr-line>,<institution>Dublin City University</institution>,<addr-line>Dublin</addr-line>,<institution>Ireland</institution>,</nlm:aff></affiliation></author><author><name sortKey="Lightfoot, Tracy" sort="Lightfoot, Tracy" uniqKey="Lightfoot T" first="Tracy" last="Lightfoot">Tracy Lightfoot</name><affiliation><nlm:aff id="af39"><addr-line>Department of Health Sciences</addr-line>,<institution>University of York</institution>,<addr-line>York</addr-line>,<country>UK</country>,</nlm:aff></affiliation></author><author><name sortKey="Crouch, Simon" sort="Crouch, Simon" uniqKey="Crouch S" first="Simon" last="Crouch">Simon Crouch</name><affiliation><nlm:aff id="af39"><addr-line>Department of Health Sciences</addr-line>,<institution>University of York</institution>,<addr-line>York</addr-line>,<country>UK</country>,</nlm:aff></affiliation></author><author><name sortKey="Smith, Alex" sort="Smith, Alex" uniqKey="Smith A" first="Alex" last="Smith">Alex Smith</name><affiliation><nlm:aff id="af39"><addr-line>Department of Health Sciences</addr-line>,<institution>University of York</institution>,<addr-line>York</addr-line>,<country>UK</country>,</nlm:aff></affiliation></author><author><name sortKey="Roman, Eve" sort="Roman, Eve" uniqKey="Roman E" first="Eve" last="Roman">Eve Roman</name><affiliation><nlm:aff id="af39"><addr-line>Department of Health Sciences</addr-line>,<institution>University of York</institution>,<addr-line>York</addr-line>,<country>UK</country>,</nlm:aff></affiliation></author><author><name sortKey="Diver, W Ryan" sort="Diver, W Ryan" uniqKey="Diver W" first="W. Ryan" last="Diver">W. Ryan Diver</name><affiliation><nlm:aff id="af8"><addr-line>Epidemiology Research Program</addr-line>,<institution>American Cancer Society</institution>,<addr-line>Atlanta, GA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Offit, Kenneth" sort="Offit, Kenneth" uniqKey="Offit K" first="Kenneth" last="Offit">Kenneth Offit</name><affiliation><nlm:aff wicri:cut=" and" id="af15"><addr-line>Department of Medicine</addr-line></nlm:aff></affiliation></author><author><name sortKey="Zelenetz, Andrew" sort="Zelenetz, Andrew" uniqKey="Zelenetz A" first="Andrew" last="Zelenetz">Andrew Zelenetz</name><affiliation><nlm:aff wicri:cut=" and" id="af15"><addr-line>Department of Medicine</addr-line></nlm:aff></affiliation></author><author><name sortKey="Klein, Robert J" sort="Klein, Robert J" uniqKey="Klein R" first="Robert J." last="Klein">Robert J. Klein</name><affiliation><nlm:aff id="af71"><addr-line>Icahn Institute for Genomics and Multiscale Biology, Department of Genetics and Genomic Sciences</addr-line>,<institution>Icahn School of Medicine at Mount Sinai</institution>,<addr-line>New York, NY</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Villano, Danylo J" sort="Villano, Danylo J" uniqKey="Villano D" first="Danylo J." last="Villano">Danylo J. Villano</name><affiliation><nlm:aff wicri:cut=" and" id="af15"><addr-line>Department of Medicine</addr-line></nlm:aff></affiliation></author><author><name sortKey="Zheng, Tongzhang" sort="Zheng, Tongzhang" uniqKey="Zheng T" first="Tongzhang" last="Zheng">Tongzhang Zheng</name><affiliation><nlm:aff wicri:cut=" and" id="af75"><addr-line>Department of Environmental Health Sciences</addr-line></nlm:aff></affiliation></author><author><name sortKey="Zhang, Yawei" sort="Zhang, Yawei" uniqKey="Zhang Y" first="Yawei" last="Zhang">Yawei Zhang</name><affiliation><nlm:aff wicri:cut=" and" id="af75"><addr-line>Department of Environmental Health Sciences</addr-line></nlm:aff></affiliation></author><author><name sortKey="Holford, Theodore R" sort="Holford, Theodore R" uniqKey="Holford T" first="Theodore R." last="Holford">Theodore R. Holford</name><affiliation><nlm:aff id="af76"><addr-line>Department of Biostatistics</addr-line>,<institution>Yale School of Public Health</institution>,<addr-line>New Haven, CT</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Turner, Jenny" sort="Turner, Jenny" uniqKey="Turner J" first="Jenny" last="Turner">Jenny Turner</name><affiliation><nlm:aff id="af77"><addr-line>Faculty of Medicine and Health Sciences</addr-line>,<institution>Macquarie University</institution>,<addr-line>Sydney, NSW</addr-line>,<country>Australia</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af78"><addr-line>Department of Histopathology</addr-line>,<institution>Douglass Hanly Moir Pathology</institution>,<addr-line>Sydney, NSW</addr-line>,<country>Australia</country>,</nlm:aff></affiliation></author><author><name sortKey="Southey, Melissa C" sort="Southey, Melissa C" uniqKey="Southey M" first="Melissa C." last="Southey">Melissa C. Southey</name><affiliation><nlm:aff id="af34"><addr-line>Genetic Epidemiology Laboratory, Department of Pathology</addr-line>,<institution>University of Melbourne</institution>,<addr-line>Melbourne, VIC</addr-line>,<country>Australia</country>,</nlm:aff></affiliation></author><author><name sortKey="Clavel, Jacqueline" sort="Clavel, Jacqueline" uniqKey="Clavel J" first="Jacqueline" last="Clavel">Jacqueline Clavel</name><affiliation><nlm:aff id="af25"><addr-line>Epidemiology of Childhood and Adolescent Cancers Group, INSERM</addr-line>,<institution>Center of Research in Epidemiology and Statistics Sorbonne Paris Cité (CRESS)</institution>,<addr-line>Paris</addr-line>,<country>France</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af26"><institution>Université Paris Descartes</institution>,<addr-line>Paris</addr-line>,<country>France</country>,</nlm:aff></affiliation></author><author><name sortKey="Virtamo, Jarmo" sort="Virtamo, Jarmo" uniqKey="Virtamo J" first="Jarmo" last="Virtamo">Jarmo Virtamo</name><affiliation><nlm:aff id="af79"><addr-line>Chronic Disease Prevention Unit</addr-line>,<institution>National Institute for Health and Welfare</institution>,<addr-line>Helsinki</addr-line>,<country>Finland</country>,</nlm:aff></affiliation></author><author><name sortKey="Weinstein, Stephanie" sort="Weinstein, Stephanie" uniqKey="Weinstein S" first="Stephanie" last="Weinstein">Stephanie Weinstein</name><affiliation><nlm:aff id="af1"><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Bethesda, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Riboli, Elio" sort="Riboli, Elio" uniqKey="Riboli E" first="Elio" last="Riboli">Elio Riboli</name><affiliation><nlm:aff id="af46"><addr-line>School of Public Health</addr-line>,<institution>Imperial College London</institution>,<addr-line>London</addr-line>,<country>UK</country>,</nlm:aff></affiliation></author><author><name sortKey="Vineis, Paolo" sort="Vineis, Paolo" uniqKey="Vineis P" first="Paolo" last="Vineis">Paolo Vineis</name><affiliation><nlm:aff wicri:cut=" and" id="af45"><addr-line>MRC-PHE Centre for Environment and Health, School of Public Health</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af80"><addr-line>Human Genetics Foundation, Turin</addr-line>,<country>Italy</country>,</nlm:aff></affiliation></author><author><name sortKey="Kaaks, Rudolph" sort="Kaaks, Rudolph" uniqKey="Kaaks R" first="Rudolph" last="Kaaks">Rudolph Kaaks</name><affiliation><nlm:aff id="af67"><addr-line>Division of Cancer Epidemiology</addr-line>,<institution>German Cancer Research Center (DKFZ)</institution>,<addr-line>Heidelberg, Baden-Württemberg</addr-line>,<institution>Germany</institution>,</nlm:aff></affiliation></author><author><name sortKey="Boeing, Heiner" sort="Boeing, Heiner" uniqKey="Boeing H" first="Heiner" last="Boeing">Heiner Boeing</name><affiliation><nlm:aff id="af81"><addr-line>Department of Epidemiology</addr-line>,<institution>German Institute for Human Nutrition</institution>,<addr-line>Potsdam</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Tj Nneland, Anne" sort="Tj Nneland, Anne" uniqKey="Tj Nneland A" first="Anne" last="Tj Nneland">Anne Tj Nneland</name><affiliation><nlm:aff id="af82"><addr-line>Danish Cancer Society Research Center, Copenhagen</addr-line>,<country>Denmark</country>,</nlm:aff></affiliation></author><author><name sortKey="Angelucci, Emanuele" sort="Angelucci, Emanuele" uniqKey="Angelucci E" first="Emanuele" last="Angelucci">Emanuele Angelucci</name><affiliation><nlm:aff id="af83"><addr-line>Hematology Unit</addr-line>,<institution>Ospedale Oncologico di Riferimento Regionale A. Businco</institution>,<addr-line>Cagliari</addr-line>,<country>Italy</country>,</nlm:aff></affiliation></author><author><name sortKey="Di Lollo, Simonetta" sort="Di Lollo, Simonetta" uniqKey="Di Lollo S" first="Simonetta" last="Di Lollo">Simonetta Di Lollo</name><affiliation><nlm:aff id="af84"><addr-line>Department of Surgery and Translational Medicine, Section of Anatomo-Pathology</addr-line>,<institution>University of Florence</institution>,<addr-line>Florence</addr-line>,<country>Italy</country>,</nlm:aff></affiliation></author><author><name sortKey="Rais, Marco" sort="Rais, Marco" uniqKey="Rais M" first="Marco" last="Rais">Marco Rais</name><affiliation><nlm:aff id="af48"><addr-line>Department of Public Health, Clinical and Molecular Medicine</addr-line>,<institution>University of Cagliari</institution>,<addr-line>Monserrato, Cagliari</addr-line>,<country>Italy</country>,</nlm:aff></affiliation></author><author><name sortKey="De Vivo, Immaculata" sort="De Vivo, Immaculata" uniqKey="De Vivo I" first="Immaculata" last="De Vivo">Immaculata De Vivo</name><affiliation><nlm:aff id="af42"><addr-line>Department of Epidemiology</addr-line>,</nlm:aff></affiliation><affiliation><nlm:aff id="af49"><addr-line>Channing Division of Network Medicine, Department of Medicine</addr-line>,<institution>Brigham and Women's Hospital and Harvard Medical School</institution>,<addr-line>Boston, MA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Giovannucci, Edward" sort="Giovannucci, Edward" uniqKey="Giovannucci E" first="Edward" last="Giovannucci">Edward Giovannucci</name><affiliation><nlm:aff id="af42"><addr-line>Department of Epidemiology</addr-line>,</nlm:aff></affiliation><affiliation><nlm:aff id="af49"><addr-line>Channing Division of Network Medicine, Department of Medicine</addr-line>,<institution>Brigham and Women's Hospital and Harvard Medical School</institution>,<addr-line>Boston, MA</addr-line>,<country>USA</country>,</nlm:aff></affiliation><affiliation><nlm:aff wicri:cut=" and" id="af43"><addr-line>Department of Nutrition</addr-line></nlm:aff></affiliation></author><author><name sortKey="Kraft, Peter" sort="Kraft, Peter" uniqKey="Kraft P" first="Peter" last="Kraft">Peter Kraft</name><affiliation><nlm:aff id="af42"><addr-line>Department of Epidemiology</addr-line>,</nlm:aff></affiliation><affiliation><nlm:aff id="af44"><addr-line>Department of Biostatistics</addr-line>,<institution>Harvard School of Public Health</institution>,<addr-line>Boston, MA</addr-line>,<institution>USA</institution>,</nlm:aff></affiliation></author><author><name sortKey="Huang, Jinyan" sort="Huang, Jinyan" uniqKey="Huang J" first="Jinyan" last="Huang">Jinyan Huang</name><affiliation><nlm:aff id="af42"><addr-line>Department of Epidemiology</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Ma, Baoshan" sort="Ma, Baoshan" uniqKey="Ma B" first="Baoshan" last="Ma">Baoshan Ma</name><affiliation><nlm:aff id="af42"><addr-line>Department of Epidemiology</addr-line>,</nlm:aff></affiliation><affiliation><nlm:aff id="af85"><addr-line>College of Information Science and Technology</addr-line>,<institution>Dalian Maritime University</institution>,<addr-line>Dalian, Liaoning Province</addr-line>,<country>China</country>,</nlm:aff></affiliation></author><author><name sortKey="Ye, Yuanqing" sort="Ye, Yuanqing" uniqKey="Ye Y" first="Yuanqing" last="Ye">Yuanqing Ye</name><affiliation><nlm:aff id="af37"><addr-line>Department of Epidemiology</addr-line>,<institution>MD Anderson Cancer Center</institution>,<addr-line>Houston, TX</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Chiu, Brian C H" sort="Chiu, Brian C H" uniqKey="Chiu B" first="Brian C. H." last="Chiu">Brian C. H. Chiu</name><affiliation><nlm:aff id="af86"><addr-line>Department of Health Studies</addr-line>,<institution>University of Chicago</institution>,<addr-line>Chicago, IL</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Liang, Liming" sort="Liang, Liming" uniqKey="Liang L" first="Liming" last="Liang">Liming Liang</name><affiliation><nlm:aff id="af42"><addr-line>Department of Epidemiology</addr-line>,</nlm:aff></affiliation><affiliation><nlm:aff id="af44"><addr-line>Department of Biostatistics</addr-line>,<institution>Harvard School of Public Health</institution>,<addr-line>Boston, MA</addr-line>,<institution>USA</institution>,</nlm:aff></affiliation></author><author><name sortKey="Park, Ju Hyun" sort="Park, Ju Hyun" uniqKey="Park J" first="Ju-Hyun" last="Park">Ju-Hyun Park</name><affiliation><nlm:aff id="af87"><addr-line>Department of Statistics</addr-line>,<institution>Dongguk University</institution>,<addr-line>Seoul</addr-line>,<country>Republic of Korea</country>,</nlm:aff></affiliation></author><author><name sortKey="Chung, Charles C" sort="Chung, Charles C" uniqKey="Chung C" first="Charles C." last="Chung">Charles C. Chung</name><affiliation><nlm:aff id="af1"><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Bethesda, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Weisenburger, Dennis D" sort="Weisenburger, Dennis D" uniqKey="Weisenburger D" first="Dennis D." last="Weisenburger">Dennis D. Weisenburger</name><affiliation><nlm:aff id="af88"><addr-line>Department of Pathology</addr-line>,<institution>City of Hope National Medical Center</institution>,<addr-line>Duarte, CA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Fraumeni, Joseph F" sort="Fraumeni, Joseph F" uniqKey="Fraumeni J" first="Joseph F." last="Fraumeni">Joseph F. Fraumeni</name><affiliation><nlm:aff id="af1"><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Bethesda, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Salles, Gilles" sort="Salles, Gilles" uniqKey="Salles G" first="Gilles" last="Salles">Gilles Salles</name><affiliation><nlm:aff id="af20"><addr-line>Laboratoire de Biologie Moléculaire de la Cellule UMR 5239</addr-line>,<institution>Centre National de la Recherche Scientifique</institution>,<addr-line>Pierre benite Cedex</addr-line>,<institution>France</institution>,</nlm:aff></affiliation><affiliation><nlm:aff id="af89"><addr-line>Department of Hematology</addr-line>,<institution>Hospices Civils de Lyon</institution>,<addr-line>Pierre benite Cedex</addr-line>,<country>France</country>,</nlm:aff></affiliation><affiliation><nlm:aff wicri:cut=" and" id="af90"><addr-line>Department of Hematology</addr-line>,<institution>Université Lyon-1</institution>,<addr-line>Pierre benite Cedex</addr-line>,<country>France</country></nlm:aff></affiliation></author><author><name sortKey="Glenn, Martha" sort="Glenn, Martha" uniqKey="Glenn M" first="Martha" last="Glenn">Martha Glenn</name><affiliation><nlm:aff id="af9"><addr-line>Department of Internal Medicine</addr-line>,<institution>University of Utah School of Medicine</institution>,<addr-line>Salt Lake City, UT</addr-line>,<institution>USA</institution>,</nlm:aff></affiliation></author><author><name sortKey="Cannon Albright, Lisa" sort="Cannon Albright, Lisa" uniqKey="Cannon Albright L" first="Lisa" last="Cannon-Albright">Lisa Cannon-Albright</name><affiliation><nlm:aff id="af9"><addr-line>Department of Internal Medicine</addr-line>,<institution>University of Utah School of Medicine</institution>,<addr-line>Salt Lake City, UT</addr-line>,<institution>USA</institution>,</nlm:aff></affiliation></author><author><name sortKey="Curtin, Karen" sort="Curtin, Karen" uniqKey="Curtin K" first="Karen" last="Curtin">Karen Curtin</name><affiliation><nlm:aff id="af9"><addr-line>Department of Internal Medicine</addr-line>,<institution>University of Utah School of Medicine</institution>,<addr-line>Salt Lake City, UT</addr-line>,<institution>USA</institution>,</nlm:aff></affiliation></author><author><name sortKey="Wu, Xifeng" sort="Wu, Xifeng" uniqKey="Wu X" first="Xifeng" last="Wu">Xifeng Wu</name><affiliation><nlm:aff id="af37"><addr-line>Department of Epidemiology</addr-line>,<institution>MD Anderson Cancer Center</institution>,<addr-line>Houston, TX</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Smedby, Karin E" sort="Smedby, Karin E" uniqKey="Smedby K" first="Karin E." last="Smedby">Karin E. Smedby</name><affiliation><nlm:aff id="af91"><addr-line>Department of Medicine, Solna</addr-line>,<institution>Karolinska Institutet, Karolinska University Hospital</institution>,<addr-line>Stockholm</addr-line>,<country>Sweden</country></nlm:aff></affiliation></author><author><name sortKey="De Sanjose, Silvia" sort="De Sanjose, Silvia" uniqKey="De Sanjose S" first="Silvia" last="De Sanjose">Silvia De Sanjose</name><affiliation><nlm:aff id="af68"><addr-line>Cancer Epidemiology Research Programme, Catalan Institute of Oncology-IDIBELL</addr-line>,<institution>L'Hospitalet de Llobregat</institution>,<addr-line>Barcelona</addr-line>,<country>Spain</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af69"><institution>CIBER de Epidemiología y Salud Pública (CIBERESP)</institution>,<addr-line>Barcelona</addr-line>,<institution>Spain</institution>,</nlm:aff></affiliation></author><author><name sortKey="Skibola, Christine F" sort="Skibola, Christine F" uniqKey="Skibola C" first="Christine F." last="Skibola">Christine F. Skibola</name><affiliation><nlm:aff wicri:cut=" and" id="af22"><addr-line>Department of Epidemiology, School of Public Health and Comprehensive Cancer Center</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af24"><addr-line>Division of Environmental Health Sciences</addr-line>,<institution>University of California Berkeley School of Public Health</institution>,<addr-line>Berkeley, CA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Berndt, Sonja I" sort="Berndt, Sonja I" uniqKey="Berndt S" first="Sonja I." last="Berndt">Sonja I. Berndt</name><affiliation><nlm:aff id="af1"><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Bethesda, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Birmann, Brenda M" sort="Birmann, Brenda M" uniqKey="Birmann B" first="Brenda M." last="Birmann">Brenda M. Birmann</name><affiliation><nlm:aff id="af49"><addr-line>Channing Division of Network Medicine, Department of Medicine</addr-line>,<institution>Brigham and Women's Hospital and Harvard Medical School</institution>,<addr-line>Boston, MA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J." last="Chanock">Stephen J. Chanock</name><affiliation><nlm:aff id="af1"><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Bethesda, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Rothman, Nathaniel" sort="Rothman, Nathaniel" uniqKey="Rothman N" first="Nathaniel" last="Rothman">Nathaniel Rothman</name><affiliation><nlm:aff id="af1"><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Bethesda, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27008888</idno><idno type="pmc">4854019</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854019</idno><idno type="RBID">PMC:4854019</idno><idno type="doi">10.1093/hmg/ddw027</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">000443</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000443</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Genetically predicted longer telomere length is associated with increased risk of B-cell lymphoma subtypes</title><author><name sortKey="Machiela, Mitchell J" sort="Machiela, Mitchell J" uniqKey="Machiela M" first="Mitchell J." last="Machiela">Mitchell J. Machiela</name><affiliation><nlm:aff id="af1"><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Bethesda, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Lan, Qing" sort="Lan, Qing" uniqKey="Lan Q" first="Qing" last="Lan">Qing Lan</name><affiliation><nlm:aff id="af1"><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Bethesda, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Slager, Susan L" sort="Slager, Susan L" uniqKey="Slager S" first="Susan L." last="Slager">Susan L. Slager</name><affiliation><nlm:aff id="af2"><addr-line>Department of Health Sciences Research</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Vermeulen, Roel C H" sort="Vermeulen, Roel C H" uniqKey="Vermeulen R" first="Roel C. H." last="Vermeulen">Roel C. H. Vermeulen</name><affiliation><nlm:aff id="af5"><addr-line>Institute for Risk Assessment Sciences</addr-line>,<institution>Utrecht University</institution>,<addr-line>Utrecht</addr-line>,<institution>The Netherlands</institution>,</nlm:aff></affiliation><affiliation><nlm:aff wicri:cut=" and" id="af6"><addr-line>Julius Center for Health Sciences and Primary Care</addr-line></nlm:aff></affiliation></author><author><name sortKey="Teras, Lauren R" sort="Teras, Lauren R" uniqKey="Teras L" first="Lauren R." last="Teras">Lauren R. Teras</name><affiliation><nlm:aff id="af8"><addr-line>Epidemiology Research Program</addr-line>,<institution>American Cancer Society</institution>,<addr-line>Atlanta, GA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Camp, Nicola J" sort="Camp, Nicola J" uniqKey="Camp N" first="Nicola J." last="Camp">Nicola J. Camp</name><affiliation><nlm:aff id="af9"><addr-line>Department of Internal Medicine</addr-line>,<institution>University of Utah School of Medicine</institution>,<addr-line>Salt Lake City, UT</addr-line>,<institution>USA</institution>,</nlm:aff></affiliation></author><author><name sortKey="Cerhan, James R" sort="Cerhan, James R" uniqKey="Cerhan J" first="James R." last="Cerhan">James R. Cerhan</name><affiliation><nlm:aff id="af2"><addr-line>Department of Health Sciences Research</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Spinelli, John J" sort="Spinelli, John J" uniqKey="Spinelli J" first="John J." last="Spinelli">John J. Spinelli</name><affiliation><nlm:aff wicri:cut=" and" id="af10"><addr-line>Cancer Control Research</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af12"><addr-line>School of Population and Public Health</addr-line>,<institution>University of British Columbia</institution>,<addr-line>Vancouver, BC</addr-line>,<country>Canada</country>,</nlm:aff></affiliation></author><author><name sortKey="Wang, Sophia S" sort="Wang, Sophia S" uniqKey="Wang S" first="Sophia S." last="Wang">Sophia S. Wang</name><affiliation><nlm:aff id="af13"><addr-line>Division of Cancer Etiology</addr-line>,<institution>City of Hope Beckman Research Institute</institution>,<addr-line>Duarte, CA</addr-line>,<institution>USA</institution>,</nlm:aff></affiliation></author><author><name sortKey="Nieters, Alexandra" sort="Nieters, Alexandra" uniqKey="Nieters A" first="Alexandra" last="Nieters">Alexandra Nieters</name><affiliation><nlm:aff id="af14"><addr-line>Center for Chronic Immunodeficiency</addr-line>,<institution>University Medical Center Freiburg</institution>,<addr-line>Freiburg, Baden-Württemberg</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Vijai, Joseph" sort="Vijai, Joseph" uniqKey="Vijai J" first="Joseph" last="Vijai">Joseph Vijai</name><affiliation><nlm:aff wicri:cut=" and" id="af15"><addr-line>Department of Medicine</addr-line></nlm:aff></affiliation></author><author><name sortKey="Yeager, Meredith" sort="Yeager, Meredith" uniqKey="Yeager M" first="Meredith" last="Yeager">Meredith Yeager</name><affiliation><nlm:aff id="af17"><addr-line>Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Gaithersburg, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Wang, Zhaoming" sort="Wang, Zhaoming" uniqKey="Wang Z" first="Zhaoming" last="Wang">Zhaoming Wang</name><affiliation><nlm:aff id="af17"><addr-line>Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Gaithersburg, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Ghesquieres, Herve" sort="Ghesquieres, Herve" uniqKey="Ghesquieres H" first="Hervé" last="Ghesquières">Hervé Ghesquières</name><affiliation><nlm:aff wicri:cut=" and" id="af18"><addr-line>Department of Hematology</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af20"><addr-line>Laboratoire de Biologie Moléculaire de la Cellule UMR 5239</addr-line>,<institution>Centre National de la Recherche Scientifique</institution>,<addr-line>Pierre benite Cedex</addr-line>,<institution>France</institution>,</nlm:aff></affiliation></author><author><name sortKey="Mckay, James" sort="Mckay, James" uniqKey="Mckay J" first="James" last="Mckay">James Mckay</name><affiliation><nlm:aff id="af21"><institution>International Agency for Research on Cancer (IARC)</institution>,<addr-line>Lyon</addr-line>,<country>France</country>,</nlm:aff></affiliation></author><author><name sortKey="Conde, Lucia" sort="Conde, Lucia" uniqKey="Conde L" first="Lucia" last="Conde">Lucia Conde</name><affiliation><nlm:aff wicri:cut=" and" id="af22"><addr-line>Department of Epidemiology, School of Public Health and Comprehensive Cancer Center</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af24"><addr-line>Division of Environmental Health Sciences</addr-line>,<institution>University of California Berkeley School of Public Health</institution>,<addr-line>Berkeley, CA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="De Bakker, Paul I W" sort="De Bakker, Paul I W" uniqKey="De Bakker P" first="Paul I. W." last="De Bakker">Paul I. W. De Bakker</name><affiliation><nlm:aff wicri:cut=" and" id="af6"><addr-line>Julius Center for Health Sciences and Primary Care</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af7"><addr-line>Department of Medical Genetics and of Epidemiology</addr-line>,<institution>University Medical Center Utrecht</institution>,<addr-line>Utrecht</addr-line>,<country>The Netherlands</country>,</nlm:aff></affiliation></author><author><name sortKey="Cox, David G" sort="Cox, David G" uniqKey="Cox D" first="David G." last="Cox">David G. Cox</name><affiliation><nlm:aff id="af19"><addr-line>INSERM U1052, Cancer Research Center of Lyon</addr-line>,<institution>Centre Léon Bérard</institution>,<addr-line>Lyon</addr-line>,<country>France</country>,</nlm:aff></affiliation></author><author><name sortKey="Burdett, Laurie" sort="Burdett, Laurie" uniqKey="Burdett L" first="Laurie" last="Burdett">Laurie Burdett</name><affiliation><nlm:aff id="af17"><addr-line>Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Gaithersburg, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Monnereau, Alain" sort="Monnereau, Alain" uniqKey="Monnereau A" first="Alain" last="Monnereau">Alain Monnereau</name><affiliation><nlm:aff id="af25"><addr-line>Epidemiology of Childhood and Adolescent Cancers Group, INSERM</addr-line>,<institution>Center of Research in Epidemiology and Statistics Sorbonne Paris Cité (CRESS)</institution>,<addr-line>Paris</addr-line>,<country>France</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af26"><institution>Université Paris Descartes</institution>,<addr-line>Paris</addr-line>,<country>France</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af27"><addr-line>Registre des hémopathies malignes de la Gironde</addr-line>,<institution>Institut Bergonié</institution>,<addr-line>Bordeaux Cedex</addr-line>,<institution>France</institution>,</nlm:aff></affiliation></author><author><name sortKey="Flowers, Christopher R" sort="Flowers, Christopher R" uniqKey="Flowers C" first="Christopher R." last="Flowers">Christopher R. Flowers</name><affiliation><nlm:aff id="af28"><addr-line>Winship Cancer Institute</addr-line>,<institution>Emory University School of Medicine</institution>,<addr-line>Atlanta, GA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="De Roos, Anneclaire J" sort="De Roos, Anneclaire J" uniqKey="De Roos A" first="Anneclaire J." last="De Roos">Anneclaire J. De Roos</name><affiliation><nlm:aff id="af29"><addr-line>Department of Environmental and Occupational Health</addr-line>,<institution>Drexel University School of Public Health</institution>,<addr-line>Philadelphia, PA</addr-line>,<country>USA</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af30"><addr-line>Division of Public Health Sciences</addr-line>,<institution>Fred Hutchinson Cancer Research Center</institution>,<addr-line>Seattle, WA</addr-line>,<institution>USA</institution>,</nlm:aff></affiliation></author><author><name sortKey="Brooks Wilson, Angela R" sort="Brooks Wilson, Angela R" uniqKey="Brooks Wilson A" first="Angela R." last="Brooks-Wilson">Angela R. Brooks-Wilson</name><affiliation><nlm:aff id="af11"><addr-line>Genome Sciences Centre</addr-line>,<institution>BC Cancer Agency</institution>,<addr-line>Vancouver, BC</addr-line>,<country>Canada</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af31"><addr-line>Department of Biomedical Physiology and Kinesiology</addr-line>,<institution>Simon Fraser University</institution>,<addr-line>Burnaby, BC</addr-line>,<institution>Canada</institution>,</nlm:aff></affiliation></author><author><name sortKey="Giles, Graham G" sort="Giles, Graham G" uniqKey="Giles G" first="Graham G." last="Giles">Graham G. Giles</name><affiliation><nlm:aff id="af32"><addr-line>Cancer Epidemiology Centre</addr-line>,<institution>Cancer Council Victoria</institution>,<addr-line>Melbourne, VIC</addr-line>,<institution>Australia</institution>,</nlm:aff></affiliation><affiliation><nlm:aff wicri:cut=" and" id="af33"><addr-line>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health</addr-line></nlm:aff></affiliation></author><author><name sortKey="Melbye, Mads" sort="Melbye, Mads" uniqKey="Melbye M" first="Mads" last="Melbye">Mads Melbye</name><affiliation><nlm:aff id="af35"><addr-line>Department of Epidemiology Research, Division of Health Surveillance and Research</addr-line>,<institution>Statens Serum Institut</institution>,<addr-line>Copenhagen</addr-line>,<country>Denmark</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af36"><addr-line>Department of Medicine</addr-line>,<institution>Stanford University School of Medicine</institution>,<addr-line>Stanford, CA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Gu, Jian" sort="Gu, Jian" uniqKey="Gu J" first="Jian" last="Gu">Jian Gu</name><affiliation><nlm:aff id="af37"><addr-line>Department of Epidemiology</addr-line>,<institution>MD Anderson Cancer Center</institution>,<addr-line>Houston, TX</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Jackson, Rebecca D" sort="Jackson, Rebecca D" uniqKey="Jackson R" first="Rebecca D." last="Jackson">Rebecca D. Jackson</name><affiliation><nlm:aff id="af38"><addr-line>Division of Endocrinology, Diabetes and Metabolism</addr-line>,<institution>The Ohio State University</institution>,<addr-line>Columbus, OH</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Kane, Eleanor" sort="Kane, Eleanor" uniqKey="Kane E" first="Eleanor" last="Kane">Eleanor Kane</name><affiliation><nlm:aff id="af39"><addr-line>Department of Health Sciences</addr-line>,<institution>University of York</institution>,<addr-line>York</addr-line>,<country>UK</country>,</nlm:aff></affiliation></author><author><name sortKey="Purdue, Mark P" sort="Purdue, Mark P" uniqKey="Purdue M" first="Mark P." last="Purdue">Mark P. Purdue</name><affiliation><nlm:aff id="af40"><addr-line>Ontario Health Study, Toronto, ON</addr-line>,<institution>Canada</institution>,</nlm:aff></affiliation></author><author><name sortKey="Vajdic, Claire M" sort="Vajdic, Claire M" uniqKey="Vajdic C" first="Claire M." last="Vajdic">Claire M. Vajdic</name><affiliation><nlm:aff id="af41"><addr-line>Centre for Big Data Research in Health</addr-line>,<institution>University of New South Wales</institution>,<addr-line>Sydney, NSW</addr-line>,<country>Australia</country>,</nlm:aff></affiliation></author><author><name sortKey="Albanes, Demetrius" sort="Albanes, Demetrius" uniqKey="Albanes D" first="Demetrius" last="Albanes">Demetrius Albanes</name><affiliation><nlm:aff id="af1"><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Bethesda, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Kelly, Rachel S" sort="Kelly, Rachel S" uniqKey="Kelly R" first="Rachel S." last="Kelly">Rachel S. Kelly</name><affiliation><nlm:aff id="af42"><addr-line>Department of Epidemiology</addr-line>,</nlm:aff></affiliation><affiliation><nlm:aff wicri:cut=" and" id="af45"><addr-line>MRC-PHE Centre for Environment and Health, School of Public Health</addr-line></nlm:aff></affiliation></author><author><name sortKey="Zucca, Mariagrazia" sort="Zucca, Mariagrazia" uniqKey="Zucca M" first="Mariagrazia" last="Zucca">Mariagrazia Zucca</name><affiliation><nlm:aff wicri:cut=" and" id="af47"><addr-line>Department of Biomedical Science</addr-line></nlm:aff></affiliation></author><author><name sortKey="Bertrand, Kimberly A" sort="Bertrand, Kimberly A" uniqKey="Bertrand K" first="Kimberly A." last="Bertrand">Kimberly A. Bertrand</name><affiliation><nlm:aff id="af42"><addr-line>Department of Epidemiology</addr-line>,</nlm:aff></affiliation><affiliation><nlm:aff id="af49"><addr-line>Channing Division of Network Medicine, Department of Medicine</addr-line>,<institution>Brigham and Women's Hospital and Harvard Medical School</institution>,<addr-line>Boston, MA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Zeleniuch Jacquotte, Anne" sort="Zeleniuch Jacquotte, Anne" uniqKey="Zeleniuch Jacquotte A" first="Anne" last="Zeleniuch-Jacquotte">Anne Zeleniuch-Jacquotte</name><affiliation><nlm:aff wicri:cut=" and" id="af50"><addr-line>Department of Population Health</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af51"><addr-line>Department of Environmental Medicine</addr-line>,<institution>New York University School of Medicine</institution>,<addr-line>New York, NY</addr-line>,<institution>USA</institution>,</nlm:aff></affiliation><affiliation><nlm:aff id="af52"><addr-line>Perlmutter Cancer Center</addr-line>,<institution>NYU Langone Medical Center</institution>,<addr-line>New York, NY</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Lawrence, Charles" sort="Lawrence, Charles" uniqKey="Lawrence C" first="Charles" last="Lawrence">Charles Lawrence</name><affiliation><nlm:aff id="af53"><institution>Westat</institution>,<addr-line>Rockville, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Hutchinson, Amy" sort="Hutchinson, Amy" uniqKey="Hutchinson A" first="Amy" last="Hutchinson">Amy Hutchinson</name><affiliation><nlm:aff id="af17"><addr-line>Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Gaithersburg, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Zhi, Degui" sort="Zhi, Degui" uniqKey="Zhi D" first="Degui" last="Zhi">Degui Zhi</name><affiliation><nlm:aff id="af23"><addr-line>Department of Biostatistics</addr-line>,<institution>University of Alabama at Birmingham</institution>,<addr-line>Birmingham, AL</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Habermann, Thomas M" sort="Habermann, Thomas M" uniqKey="Habermann T" first="Thomas M." last="Habermann">Thomas M. Habermann</name><affiliation><nlm:aff wicri:cut=" and" id="af3"><addr-line>Department of Medicine</addr-line></nlm:aff></affiliation></author><author><name sortKey="Link, Brian K" sort="Link, Brian K" uniqKey="Link B" first="Brian K." last="Link">Brian K. Link</name><affiliation><nlm:aff id="af54"><addr-line>Department of Internal Medicine, Carver College of Medicine</addr-line>,<institution>The University of Iowa</institution>,<addr-line>Iowa City, IA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Novak, Anne J" sort="Novak, Anne J" uniqKey="Novak A" first="Anne J." last="Novak">Anne J. Novak</name><affiliation><nlm:aff wicri:cut=" and" id="af3"><addr-line>Department of Medicine</addr-line></nlm:aff></affiliation></author><author><name sortKey="Dogan, Ahmet" sort="Dogan, Ahmet" uniqKey="Dogan A" first="Ahmet" last="Dogan">Ahmet Dogan</name><affiliation><nlm:aff id="af16"><addr-line>Departments of Laboratory Medicine and Pathology</addr-line>,<institution>Memorial Sloan Kettering Cancer Center</institution>,<addr-line>New York, NY</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Asmann, Yan W" sort="Asmann, Yan W" uniqKey="Asmann Y" first="Yan W." last="Asmann">Yan W. Asmann</name><affiliation><nlm:aff id="af4"><addr-line>Division of Biomedical Statistics and Informatics, Department of Health Sciences Research</addr-line>,<institution>Mayo Clinic</institution>,<addr-line>Rochester, MN</addr-line>,<institution>USA</institution>,</nlm:aff></affiliation></author><author><name sortKey="Liebow, Mark" sort="Liebow, Mark" uniqKey="Liebow M" first="Mark" last="Liebow">Mark Liebow</name><affiliation><nlm:aff wicri:cut=" and" id="af3"><addr-line>Department of Medicine</addr-line></nlm:aff></affiliation></author><author><name sortKey="Thompson, Carrie A" sort="Thompson, Carrie A" uniqKey="Thompson C" first="Carrie A." last="Thompson">Carrie A. Thompson</name><affiliation><nlm:aff wicri:cut=" and" id="af3"><addr-line>Department of Medicine</addr-line></nlm:aff></affiliation></author><author><name sortKey="Ansell, Stephen M" sort="Ansell, Stephen M" uniqKey="Ansell S" first="Stephen M." last="Ansell">Stephen M. Ansell</name><affiliation><nlm:aff wicri:cut=" and" id="af3"><addr-line>Department of Medicine</addr-line></nlm:aff></affiliation></author><author><name sortKey="Witzig, Thomas E" sort="Witzig, Thomas E" uniqKey="Witzig T" first="Thomas E." last="Witzig">Thomas E. Witzig</name><affiliation><nlm:aff wicri:cut=" and" id="af3"><addr-line>Department of Medicine</addr-line></nlm:aff></affiliation></author><author><name sortKey="Tilly, Herve" sort="Tilly, Herve" uniqKey="Tilly H" first="Hervé" last="Tilly">Hervé Tilly</name><affiliation><nlm:aff id="af55"><addr-line>Centre Heni Becquerel</addr-line>,<institution>Université de Rouen</institution>,<addr-line>Rouen</addr-line>,<country>France</country>,</nlm:aff></affiliation></author><author><name sortKey="Haioun, Corinne" sort="Haioun, Corinne" uniqKey="Haioun C" first="Corinne" last="Haioun">Corinne Haioun</name><affiliation><nlm:aff id="af56"><addr-line>Lymphoid Malignancies Unit</addr-line>,<institution>Henri Mondor Hospital and University Paris Est</institution>,<addr-line>Créteil</addr-line>,<country>France</country>,</nlm:aff></affiliation></author><author><name sortKey="Molina, Thierry J" sort="Molina, Thierry J" uniqKey="Molina T" first="Thierry J." last="Molina">Thierry J. Molina</name><affiliation><nlm:aff id="af57"><addr-line>Department of Pathology, AP-HP, Necker Enfants malades</addr-line>,<institution>Université Paris Descartes</institution>,<addr-line>Sorbonne Paris Cité</addr-line>,<country>France</country>,</nlm:aff></affiliation></author><author><name sortKey="Hjalgrim, Henrik" sort="Hjalgrim, Henrik" uniqKey="Hjalgrim H" first="Henrik" last="Hjalgrim">Henrik Hjalgrim</name><affiliation><nlm:aff id="af35"><addr-line>Department of Epidemiology Research, Division of Health Surveillance and Research</addr-line>,<institution>Statens Serum Institut</institution>,<addr-line>Copenhagen</addr-line>,<country>Denmark</country>,</nlm:aff></affiliation></author><author><name sortKey="Glimelius, Bengt" sort="Glimelius, Bengt" uniqKey="Glimelius B" first="Bengt" last="Glimelius">Bengt Glimelius</name><affiliation><nlm:aff id="af58"><addr-line>Department of Immunology, Genetics and Pathology</addr-line>,<institution>Uppsala University</institution>,<addr-line>Uppsala</addr-line>,<country>Sweden</country>,</nlm:aff></affiliation></author><author><name sortKey="Adami, Hans Olov" sort="Adami, Hans Olov" uniqKey="Adami H" first="Hans-Olov" last="Adami">Hans-Olov Adami</name><affiliation><nlm:aff id="af42"><addr-line>Department of Epidemiology</addr-line>,</nlm:aff></affiliation><affiliation><nlm:aff id="af59"><addr-line>Department of Medical Epidemiology and Biostatistics</addr-line>,<institution>Karolinska Institutet</institution>,<addr-line>Stockholm</addr-line>,<country>Sweden</country>,</nlm:aff></affiliation></author><author><name sortKey="Roos, Goran" sort="Roos, Goran" uniqKey="Roos G" first="Göran" last="Roos">Göran Roos</name><affiliation><nlm:aff id="af60"><addr-line>Department of Medical Biosciences</addr-line>,<institution>Umeå University</institution>,<addr-line>Umeå</addr-line>,<country>Sweden</country>,</nlm:aff></affiliation></author><author><name sortKey="Bracci, Paige M" sort="Bracci, Paige M" uniqKey="Bracci P" first="Paige M." last="Bracci">Paige M. Bracci</name><affiliation><nlm:aff id="af61"><addr-line>Department of Epidemiology and Biostatistics</addr-line>,<institution>University of California San Francisco</institution>,<addr-line>San Francisco, CA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Riby, Jacques" sort="Riby, Jacques" uniqKey="Riby J" first="Jacques" last="Riby">Jacques Riby</name><affiliation><nlm:aff wicri:cut=" and" id="af22"><addr-line>Department of Epidemiology, School of Public Health and Comprehensive Cancer Center</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af24"><addr-line>Division of Environmental Health Sciences</addr-line>,<institution>University of California Berkeley School of Public Health</institution>,<addr-line>Berkeley, CA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Smith, Martyn T" sort="Smith, Martyn T" uniqKey="Smith M" first="Martyn T." last="Smith">Martyn T. Smith</name><affiliation><nlm:aff id="af24"><addr-line>Division of Environmental Health Sciences</addr-line>,<institution>University of California Berkeley School of Public Health</institution>,<addr-line>Berkeley, CA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Holly, Elizabeth A" sort="Holly, Elizabeth A" uniqKey="Holly E" first="Elizabeth A." last="Holly">Elizabeth A. Holly</name><affiliation><nlm:aff id="af61"><addr-line>Department of Epidemiology and Biostatistics</addr-line>,<institution>University of California San Francisco</institution>,<addr-line>San Francisco, CA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Cozen, Wendy" sort="Cozen, Wendy" uniqKey="Cozen W" first="Wendy" last="Cozen">Wendy Cozen</name><affiliation><nlm:aff wicri:cut=" and" id="af62"><addr-line>Department of Preventive Medicine</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af63"><addr-line>Norris Comprehensive Cancer Center, USC Keck School of Medicine</addr-line>,<institution>University of Southern California</institution>,<addr-line>Los Angeles, CA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Hartge, Patricia" sort="Hartge, Patricia" uniqKey="Hartge P" first="Patricia" last="Hartge">Patricia Hartge</name><affiliation><nlm:aff id="af1"><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Bethesda, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Morton, Lindsay M" sort="Morton, Lindsay M" uniqKey="Morton L" first="Lindsay M." last="Morton">Lindsay M. Morton</name><affiliation><nlm:aff id="af1"><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Bethesda, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Severson, Richard K" sort="Severson, Richard K" uniqKey="Severson R" first="Richard K." last="Severson">Richard K. Severson</name><affiliation><nlm:aff id="af64"><addr-line>Department of Family Medicine and Public Health Sciences</addr-line>,<institution>Wayne State University</institution>,<addr-line>Detroit, MI</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Tinker, Lesley F" sort="Tinker, Lesley F" uniqKey="Tinker L" first="Lesley F." last="Tinker">Lesley F. Tinker</name><affiliation><nlm:aff id="af30"><addr-line>Division of Public Health Sciences</addr-line>,<institution>Fred Hutchinson Cancer Research Center</institution>,<addr-line>Seattle, WA</addr-line>,<institution>USA</institution>,</nlm:aff></affiliation></author><author><name sortKey="North, Kari E" sort="North, Kari E" uniqKey="North K" first="Kari E." last="North">Kari E. North</name><affiliation><nlm:aff wicri:cut=" and" id="af65"><addr-line>Department of Epidemiology</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af66"><addr-line>Carolina Center for Genome Sciences</addr-line>,<institution>University of North Carolina at Chapel Hill</institution>,<addr-line>Chapel Hill, NC</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Becker, Nikolaus" sort="Becker, Nikolaus" uniqKey="Becker N" first="Nikolaus" last="Becker">Nikolaus Becker</name><affiliation><nlm:aff id="af67"><addr-line>Division of Cancer Epidemiology</addr-line>,<institution>German Cancer Research Center (DKFZ)</institution>,<addr-line>Heidelberg, Baden-Württemberg</addr-line>,<institution>Germany</institution>,</nlm:aff></affiliation></author><author><name sortKey="Benavente, Yolanda" sort="Benavente, Yolanda" uniqKey="Benavente Y" first="Yolanda" last="Benavente">Yolanda Benavente</name><affiliation><nlm:aff id="af68"><addr-line>Cancer Epidemiology Research Programme, Catalan Institute of Oncology-IDIBELL</addr-line>,<institution>L'Hospitalet de Llobregat</institution>,<addr-line>Barcelona</addr-line>,<country>Spain</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af69"><institution>CIBER de Epidemiología y Salud Pública (CIBERESP)</institution>,<addr-line>Barcelona</addr-line>,<institution>Spain</institution>,</nlm:aff></affiliation></author><author><name sortKey="Boffetta, Paolo" sort="Boffetta, Paolo" uniqKey="Boffetta P" first="Paolo" last="Boffetta">Paolo Boffetta</name><affiliation><nlm:aff wicri:cut=" and" id="af70"><addr-line>The Tisch Cancer Institute</addr-line></nlm:aff></affiliation></author><author><name sortKey="Brennan, Paul" sort="Brennan, Paul" uniqKey="Brennan P" first="Paul" last="Brennan">Paul Brennan</name><affiliation><nlm:aff id="af21"><institution>International Agency for Research on Cancer (IARC)</institution>,<addr-line>Lyon</addr-line>,<country>France</country>,</nlm:aff></affiliation></author><author><name sortKey="Foretova, Lenka" sort="Foretova, Lenka" uniqKey="Foretova L" first="Lenka" last="Foretova">Lenka Foretova</name><affiliation><nlm:aff id="af72"><addr-line>Department of Cancer Epidemiology and Genetics</addr-line>,<institution>Masaryk Memorial Cancer Institute and MF MU</institution>,<addr-line>Brno</addr-line>,<country>Czech Republic</country>,</nlm:aff></affiliation></author><author><name sortKey="Maynadie, Marc" sort="Maynadie, Marc" uniqKey="Maynadie M" first="Marc" last="Maynadie">Marc Maynadie</name><affiliation><nlm:aff id="af73"><addr-line>EA 4184, Registre des Hémopathies Malignes de Côte d'Or</addr-line>,<institution>University of Burgundy and Dijon University Hospital</institution>,<addr-line>Dijon</addr-line>,<country>France</country>,</nlm:aff></affiliation></author><author><name sortKey="Staines, Anthony" sort="Staines, Anthony" uniqKey="Staines A" first="Anthony" last="Staines">Anthony Staines</name><affiliation><nlm:aff id="af74"><addr-line>School of Nursing and Human Sciences</addr-line>,<institution>Dublin City University</institution>,<addr-line>Dublin</addr-line>,<institution>Ireland</institution>,</nlm:aff></affiliation></author><author><name sortKey="Lightfoot, Tracy" sort="Lightfoot, Tracy" uniqKey="Lightfoot T" first="Tracy" last="Lightfoot">Tracy Lightfoot</name><affiliation><nlm:aff id="af39"><addr-line>Department of Health Sciences</addr-line>,<institution>University of York</institution>,<addr-line>York</addr-line>,<country>UK</country>,</nlm:aff></affiliation></author><author><name sortKey="Crouch, Simon" sort="Crouch, Simon" uniqKey="Crouch S" first="Simon" last="Crouch">Simon Crouch</name><affiliation><nlm:aff id="af39"><addr-line>Department of Health Sciences</addr-line>,<institution>University of York</institution>,<addr-line>York</addr-line>,<country>UK</country>,</nlm:aff></affiliation></author><author><name sortKey="Smith, Alex" sort="Smith, Alex" uniqKey="Smith A" first="Alex" last="Smith">Alex Smith</name><affiliation><nlm:aff id="af39"><addr-line>Department of Health Sciences</addr-line>,<institution>University of York</institution>,<addr-line>York</addr-line>,<country>UK</country>,</nlm:aff></affiliation></author><author><name sortKey="Roman, Eve" sort="Roman, Eve" uniqKey="Roman E" first="Eve" last="Roman">Eve Roman</name><affiliation><nlm:aff id="af39"><addr-line>Department of Health Sciences</addr-line>,<institution>University of York</institution>,<addr-line>York</addr-line>,<country>UK</country>,</nlm:aff></affiliation></author><author><name sortKey="Diver, W Ryan" sort="Diver, W Ryan" uniqKey="Diver W" first="W. Ryan" last="Diver">W. Ryan Diver</name><affiliation><nlm:aff id="af8"><addr-line>Epidemiology Research Program</addr-line>,<institution>American Cancer Society</institution>,<addr-line>Atlanta, GA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Offit, Kenneth" sort="Offit, Kenneth" uniqKey="Offit K" first="Kenneth" last="Offit">Kenneth Offit</name><affiliation><nlm:aff wicri:cut=" and" id="af15"><addr-line>Department of Medicine</addr-line></nlm:aff></affiliation></author><author><name sortKey="Zelenetz, Andrew" sort="Zelenetz, Andrew" uniqKey="Zelenetz A" first="Andrew" last="Zelenetz">Andrew Zelenetz</name><affiliation><nlm:aff wicri:cut=" and" id="af15"><addr-line>Department of Medicine</addr-line></nlm:aff></affiliation></author><author><name sortKey="Klein, Robert J" sort="Klein, Robert J" uniqKey="Klein R" first="Robert J." last="Klein">Robert J. Klein</name><affiliation><nlm:aff id="af71"><addr-line>Icahn Institute for Genomics and Multiscale Biology, Department of Genetics and Genomic Sciences</addr-line>,<institution>Icahn School of Medicine at Mount Sinai</institution>,<addr-line>New York, NY</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Villano, Danylo J" sort="Villano, Danylo J" uniqKey="Villano D" first="Danylo J." last="Villano">Danylo J. Villano</name><affiliation><nlm:aff wicri:cut=" and" id="af15"><addr-line>Department of Medicine</addr-line></nlm:aff></affiliation></author><author><name sortKey="Zheng, Tongzhang" sort="Zheng, Tongzhang" uniqKey="Zheng T" first="Tongzhang" last="Zheng">Tongzhang Zheng</name><affiliation><nlm:aff wicri:cut=" and" id="af75"><addr-line>Department of Environmental Health Sciences</addr-line></nlm:aff></affiliation></author><author><name sortKey="Zhang, Yawei" sort="Zhang, Yawei" uniqKey="Zhang Y" first="Yawei" last="Zhang">Yawei Zhang</name><affiliation><nlm:aff wicri:cut=" and" id="af75"><addr-line>Department of Environmental Health Sciences</addr-line></nlm:aff></affiliation></author><author><name sortKey="Holford, Theodore R" sort="Holford, Theodore R" uniqKey="Holford T" first="Theodore R." last="Holford">Theodore R. Holford</name><affiliation><nlm:aff id="af76"><addr-line>Department of Biostatistics</addr-line>,<institution>Yale School of Public Health</institution>,<addr-line>New Haven, CT</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Turner, Jenny" sort="Turner, Jenny" uniqKey="Turner J" first="Jenny" last="Turner">Jenny Turner</name><affiliation><nlm:aff id="af77"><addr-line>Faculty of Medicine and Health Sciences</addr-line>,<institution>Macquarie University</institution>,<addr-line>Sydney, NSW</addr-line>,<country>Australia</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af78"><addr-line>Department of Histopathology</addr-line>,<institution>Douglass Hanly Moir Pathology</institution>,<addr-line>Sydney, NSW</addr-line>,<country>Australia</country>,</nlm:aff></affiliation></author><author><name sortKey="Southey, Melissa C" sort="Southey, Melissa C" uniqKey="Southey M" first="Melissa C." last="Southey">Melissa C. Southey</name><affiliation><nlm:aff id="af34"><addr-line>Genetic Epidemiology Laboratory, Department of Pathology</addr-line>,<institution>University of Melbourne</institution>,<addr-line>Melbourne, VIC</addr-line>,<country>Australia</country>,</nlm:aff></affiliation></author><author><name sortKey="Clavel, Jacqueline" sort="Clavel, Jacqueline" uniqKey="Clavel J" first="Jacqueline" last="Clavel">Jacqueline Clavel</name><affiliation><nlm:aff id="af25"><addr-line>Epidemiology of Childhood and Adolescent Cancers Group, INSERM</addr-line>,<institution>Center of Research in Epidemiology and Statistics Sorbonne Paris Cité (CRESS)</institution>,<addr-line>Paris</addr-line>,<country>France</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af26"><institution>Université Paris Descartes</institution>,<addr-line>Paris</addr-line>,<country>France</country>,</nlm:aff></affiliation></author><author><name sortKey="Virtamo, Jarmo" sort="Virtamo, Jarmo" uniqKey="Virtamo J" first="Jarmo" last="Virtamo">Jarmo Virtamo</name><affiliation><nlm:aff id="af79"><addr-line>Chronic Disease Prevention Unit</addr-line>,<institution>National Institute for Health and Welfare</institution>,<addr-line>Helsinki</addr-line>,<country>Finland</country>,</nlm:aff></affiliation></author><author><name sortKey="Weinstein, Stephanie" sort="Weinstein, Stephanie" uniqKey="Weinstein S" first="Stephanie" last="Weinstein">Stephanie Weinstein</name><affiliation><nlm:aff id="af1"><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Bethesda, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Riboli, Elio" sort="Riboli, Elio" uniqKey="Riboli E" first="Elio" last="Riboli">Elio Riboli</name><affiliation><nlm:aff id="af46"><addr-line>School of Public Health</addr-line>,<institution>Imperial College London</institution>,<addr-line>London</addr-line>,<country>UK</country>,</nlm:aff></affiliation></author><author><name sortKey="Vineis, Paolo" sort="Vineis, Paolo" uniqKey="Vineis P" first="Paolo" last="Vineis">Paolo Vineis</name><affiliation><nlm:aff wicri:cut=" and" id="af45"><addr-line>MRC-PHE Centre for Environment and Health, School of Public Health</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af80"><addr-line>Human Genetics Foundation, Turin</addr-line>,<country>Italy</country>,</nlm:aff></affiliation></author><author><name sortKey="Kaaks, Rudolph" sort="Kaaks, Rudolph" uniqKey="Kaaks R" first="Rudolph" last="Kaaks">Rudolph Kaaks</name><affiliation><nlm:aff id="af67"><addr-line>Division of Cancer Epidemiology</addr-line>,<institution>German Cancer Research Center (DKFZ)</institution>,<addr-line>Heidelberg, Baden-Württemberg</addr-line>,<institution>Germany</institution>,</nlm:aff></affiliation></author><author><name sortKey="Boeing, Heiner" sort="Boeing, Heiner" uniqKey="Boeing H" first="Heiner" last="Boeing">Heiner Boeing</name><affiliation><nlm:aff id="af81"><addr-line>Department of Epidemiology</addr-line>,<institution>German Institute for Human Nutrition</institution>,<addr-line>Potsdam</addr-line>,<country>Germany</country>,</nlm:aff></affiliation></author><author><name sortKey="Tj Nneland, Anne" sort="Tj Nneland, Anne" uniqKey="Tj Nneland A" first="Anne" last="Tj Nneland">Anne Tj Nneland</name><affiliation><nlm:aff id="af82"><addr-line>Danish Cancer Society Research Center, Copenhagen</addr-line>,<country>Denmark</country>,</nlm:aff></affiliation></author><author><name sortKey="Angelucci, Emanuele" sort="Angelucci, Emanuele" uniqKey="Angelucci E" first="Emanuele" last="Angelucci">Emanuele Angelucci</name><affiliation><nlm:aff id="af83"><addr-line>Hematology Unit</addr-line>,<institution>Ospedale Oncologico di Riferimento Regionale A. Businco</institution>,<addr-line>Cagliari</addr-line>,<country>Italy</country>,</nlm:aff></affiliation></author><author><name sortKey="Di Lollo, Simonetta" sort="Di Lollo, Simonetta" uniqKey="Di Lollo S" first="Simonetta" last="Di Lollo">Simonetta Di Lollo</name><affiliation><nlm:aff id="af84"><addr-line>Department of Surgery and Translational Medicine, Section of Anatomo-Pathology</addr-line>,<institution>University of Florence</institution>,<addr-line>Florence</addr-line>,<country>Italy</country>,</nlm:aff></affiliation></author><author><name sortKey="Rais, Marco" sort="Rais, Marco" uniqKey="Rais M" first="Marco" last="Rais">Marco Rais</name><affiliation><nlm:aff id="af48"><addr-line>Department of Public Health, Clinical and Molecular Medicine</addr-line>,<institution>University of Cagliari</institution>,<addr-line>Monserrato, Cagliari</addr-line>,<country>Italy</country>,</nlm:aff></affiliation></author><author><name sortKey="De Vivo, Immaculata" sort="De Vivo, Immaculata" uniqKey="De Vivo I" first="Immaculata" last="De Vivo">Immaculata De Vivo</name><affiliation><nlm:aff id="af42"><addr-line>Department of Epidemiology</addr-line>,</nlm:aff></affiliation><affiliation><nlm:aff id="af49"><addr-line>Channing Division of Network Medicine, Department of Medicine</addr-line>,<institution>Brigham and Women's Hospital and Harvard Medical School</institution>,<addr-line>Boston, MA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Giovannucci, Edward" sort="Giovannucci, Edward" uniqKey="Giovannucci E" first="Edward" last="Giovannucci">Edward Giovannucci</name><affiliation><nlm:aff id="af42"><addr-line>Department of Epidemiology</addr-line>,</nlm:aff></affiliation><affiliation><nlm:aff id="af49"><addr-line>Channing Division of Network Medicine, Department of Medicine</addr-line>,<institution>Brigham and Women's Hospital and Harvard Medical School</institution>,<addr-line>Boston, MA</addr-line>,<country>USA</country>,</nlm:aff></affiliation><affiliation><nlm:aff wicri:cut=" and" id="af43"><addr-line>Department of Nutrition</addr-line></nlm:aff></affiliation></author><author><name sortKey="Kraft, Peter" sort="Kraft, Peter" uniqKey="Kraft P" first="Peter" last="Kraft">Peter Kraft</name><affiliation><nlm:aff id="af42"><addr-line>Department of Epidemiology</addr-line>,</nlm:aff></affiliation><affiliation><nlm:aff id="af44"><addr-line>Department of Biostatistics</addr-line>,<institution>Harvard School of Public Health</institution>,<addr-line>Boston, MA</addr-line>,<institution>USA</institution>,</nlm:aff></affiliation></author><author><name sortKey="Huang, Jinyan" sort="Huang, Jinyan" uniqKey="Huang J" first="Jinyan" last="Huang">Jinyan Huang</name><affiliation><nlm:aff id="af42"><addr-line>Department of Epidemiology</addr-line>,</nlm:aff></affiliation></author><author><name sortKey="Ma, Baoshan" sort="Ma, Baoshan" uniqKey="Ma B" first="Baoshan" last="Ma">Baoshan Ma</name><affiliation><nlm:aff id="af42"><addr-line>Department of Epidemiology</addr-line>,</nlm:aff></affiliation><affiliation><nlm:aff id="af85"><addr-line>College of Information Science and Technology</addr-line>,<institution>Dalian Maritime University</institution>,<addr-line>Dalian, Liaoning Province</addr-line>,<country>China</country>,</nlm:aff></affiliation></author><author><name sortKey="Ye, Yuanqing" sort="Ye, Yuanqing" uniqKey="Ye Y" first="Yuanqing" last="Ye">Yuanqing Ye</name><affiliation><nlm:aff id="af37"><addr-line>Department of Epidemiology</addr-line>,<institution>MD Anderson Cancer Center</institution>,<addr-line>Houston, TX</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Chiu, Brian C H" sort="Chiu, Brian C H" uniqKey="Chiu B" first="Brian C. H." last="Chiu">Brian C. H. Chiu</name><affiliation><nlm:aff id="af86"><addr-line>Department of Health Studies</addr-line>,<institution>University of Chicago</institution>,<addr-line>Chicago, IL</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Liang, Liming" sort="Liang, Liming" uniqKey="Liang L" first="Liming" last="Liang">Liming Liang</name><affiliation><nlm:aff id="af42"><addr-line>Department of Epidemiology</addr-line>,</nlm:aff></affiliation><affiliation><nlm:aff id="af44"><addr-line>Department of Biostatistics</addr-line>,<institution>Harvard School of Public Health</institution>,<addr-line>Boston, MA</addr-line>,<institution>USA</institution>,</nlm:aff></affiliation></author><author><name sortKey="Park, Ju Hyun" sort="Park, Ju Hyun" uniqKey="Park J" first="Ju-Hyun" last="Park">Ju-Hyun Park</name><affiliation><nlm:aff id="af87"><addr-line>Department of Statistics</addr-line>,<institution>Dongguk University</institution>,<addr-line>Seoul</addr-line>,<country>Republic of Korea</country>,</nlm:aff></affiliation></author><author><name sortKey="Chung, Charles C" sort="Chung, Charles C" uniqKey="Chung C" first="Charles C." last="Chung">Charles C. Chung</name><affiliation><nlm:aff id="af1"><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Bethesda, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Weisenburger, Dennis D" sort="Weisenburger, Dennis D" uniqKey="Weisenburger D" first="Dennis D." last="Weisenburger">Dennis D. Weisenburger</name><affiliation><nlm:aff id="af88"><addr-line>Department of Pathology</addr-line>,<institution>City of Hope National Medical Center</institution>,<addr-line>Duarte, CA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Fraumeni, Joseph F" sort="Fraumeni, Joseph F" uniqKey="Fraumeni J" first="Joseph F." last="Fraumeni">Joseph F. 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Smedby</name><affiliation><nlm:aff id="af91"><addr-line>Department of Medicine, Solna</addr-line>,<institution>Karolinska Institutet, Karolinska University Hospital</institution>,<addr-line>Stockholm</addr-line>,<country>Sweden</country></nlm:aff></affiliation></author><author><name sortKey="De Sanjose, Silvia" sort="De Sanjose, Silvia" uniqKey="De Sanjose S" first="Silvia" last="De Sanjose">Silvia De Sanjose</name><affiliation><nlm:aff id="af68"><addr-line>Cancer Epidemiology Research Programme, Catalan Institute of Oncology-IDIBELL</addr-line>,<institution>L'Hospitalet de Llobregat</institution>,<addr-line>Barcelona</addr-line>,<country>Spain</country>,</nlm:aff></affiliation><affiliation><nlm:aff id="af69"><institution>CIBER de Epidemiología y Salud Pública (CIBERESP)</institution>,<addr-line>Barcelona</addr-line>,<institution>Spain</institution>,</nlm:aff></affiliation></author><author><name sortKey="Skibola, Christine F" sort="Skibola, Christine F" uniqKey="Skibola C" first="Christine F." last="Skibola">Christine F. Skibola</name><affiliation><nlm:aff wicri:cut=" and" id="af22"><addr-line>Department of Epidemiology, School of Public Health and Comprehensive Cancer Center</addr-line></nlm:aff></affiliation><affiliation><nlm:aff id="af24"><addr-line>Division of Environmental Health Sciences</addr-line>,<institution>University of California Berkeley School of Public Health</institution>,<addr-line>Berkeley, CA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Berndt, Sonja I" sort="Berndt, Sonja I" uniqKey="Berndt S" first="Sonja I." last="Berndt">Sonja I. Berndt</name><affiliation><nlm:aff id="af1"><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Bethesda, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Birmann, Brenda M" sort="Birmann, Brenda M" uniqKey="Birmann B" first="Brenda M." last="Birmann">Brenda M. Birmann</name><affiliation><nlm:aff id="af49"><addr-line>Channing Division of Network Medicine, Department of Medicine</addr-line>,<institution>Brigham and Women's Hospital and Harvard Medical School</institution>,<addr-line>Boston, MA</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J." last="Chanock">Stephen J. Chanock</name><affiliation><nlm:aff id="af1"><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Bethesda, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author><author><name sortKey="Rothman, Nathaniel" sort="Rothman, Nathaniel" uniqKey="Rothman N" first="Nathaniel" last="Rothman">Nathaniel Rothman</name><affiliation><nlm:aff id="af1"><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Bethesda, MD</addr-line>,<country>USA</country>,</nlm:aff></affiliation></author></analytic><series><title level="j">Human Molecular Genetics</title><idno type="ISSN">0964-6906</idno><idno type="eISSN">1460-2083</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Evidence from a small number of studies suggests that longer telomere length measured in peripheral leukocytes is associated with an increased risk of non-Hodgkin lymphoma (NHL). However, these studies may be biased by reverse causation, confounded by unmeasured environmental exposures and might miss time points for which prospective telomere measurement would best reveal a relationship between telomere length and NHL risk. We performed an analysis of genetically inferred telomere length and NHL risk in a study of 10 102 NHL cases of the four most common B-cell histologic types and 9562 controls using a genetic risk score (GRS) comprising nine telomere length-associated single-nucleotide polymorphisms. This approach uses existing genotype data and estimates telomere length by weighing the number of telomere length-associated variant alleles an individual carries with the published change in kb of telomere length. The analysis of the telomere length GRS resulted in an association between longer telomere length and increased NHL risk [four B-cell histologic types combined; odds ratio (OR) = 1.49, 95% CI 1.22–1.82, <italic>P</italic>-value = 8.5 × 10<sup>−5</sup>]. Subtype-specific analyses indicated that chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL/SLL) was the principal NHL subtype contributing to this association (OR = 2.60, 95% CI 1.93–3.51, <italic>P</italic>-value = 4.0 × 10<sup>−10</sup>). Significant interactions were observed across strata of sex for CLL/SLL and marginal zone lymphoma subtypes as well as age for the follicular lymphoma subtype. Our results indicate that a genetic background that favors longer telomere length may increase NHL risk, particularly risk of CLL/SLL, and are consistent with earlier studies relating longer telomere length with increased NHL risk.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Hum Mol Genet</journal-id><journal-id journal-id-type="iso-abbrev">Hum. Mol. Genet</journal-id><journal-id journal-id-type="publisher-id">hmg</journal-id><journal-id journal-id-type="hwp">hmg</journal-id><journal-title-group><journal-title>Human Molecular Genetics</journal-title></journal-title-group><issn pub-type="ppub">0964-6906</issn><issn pub-type="epub">1460-2083</issn><publisher><publisher-name>Oxford University Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">27008888</article-id><article-id pub-id-type="pmc">4854019</article-id><article-id pub-id-type="doi">10.1093/hmg/ddw027</article-id><article-id pub-id-type="publisher-id">ddw027</article-id><article-categories><subj-group subj-group-type="heading"><subject>Association Studies Article</subject></subj-group></article-categories><title-group><article-title>Genetically predicted longer telomere length is associated with increased risk of B-cell lymphoma subtypes</article-title></title-group><contrib-group><contrib 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rid="af75">75</xref></contrib><contrib contrib-type="author"><name><surname>Holford</surname><given-names>Theodore R.</given-names></name><xref ref-type="aff" rid="af76">76</xref></contrib><contrib contrib-type="author"><name><surname>Turner</surname><given-names>Jenny</given-names></name><xref ref-type="aff" rid="af77">77</xref><xref ref-type="aff" rid="af78">78</xref></contrib><contrib contrib-type="author"><name><surname>Southey</surname><given-names>Melissa C.</given-names></name><xref ref-type="aff" rid="af34">34</xref></contrib><contrib contrib-type="author"><name><surname>Clavel</surname><given-names>Jacqueline</given-names></name><xref ref-type="aff" rid="af25">25</xref><xref ref-type="aff" rid="af26">26</xref></contrib><contrib contrib-type="author"><name><surname>Virtamo</surname><given-names>Jarmo</given-names></name><xref ref-type="aff" rid="af79">79</xref></contrib><contrib contrib-type="author"><name><surname>Weinstein</surname><given-names>Stephanie</given-names></name><xref ref-type="aff" rid="af1">1</xref></contrib><contrib contrib-type="author"><name><surname>Riboli</surname><given-names>Elio</given-names></name><xref ref-type="aff" rid="af46">46</xref></contrib><contrib contrib-type="author"><name><surname>Vineis</surname><given-names>Paolo</given-names></name><xref ref-type="aff" rid="af45">45</xref><xref ref-type="aff" rid="af80">80</xref></contrib><contrib contrib-type="author"><name><surname>Kaaks</surname><given-names>Rudolph</given-names></name><xref ref-type="aff" rid="af67">67</xref></contrib><contrib contrib-type="author"><name><surname>Boeing</surname><given-names>Heiner</given-names></name><xref ref-type="aff" rid="af81">81</xref></contrib><contrib contrib-type="author"><name><surname>Tjønneland</surname><given-names>Anne</given-names></name><xref ref-type="aff" rid="af82">82</xref></contrib><contrib contrib-type="author"><name><surname>Angelucci</surname><given-names>Emanuele</given-names></name><xref ref-type="aff" rid="af83">83</xref></contrib><contrib contrib-type="author"><name><surname>Di Lollo</surname><given-names>Simonetta</given-names></name><xref ref-type="aff" rid="af84">84</xref></contrib><contrib contrib-type="author"><name><surname>Rais</surname><given-names>Marco</given-names></name><xref ref-type="aff" rid="af48">48</xref></contrib><contrib contrib-type="author"><name><surname>De Vivo</surname><given-names>Immaculata</given-names></name><xref ref-type="aff" rid="af42">42</xref><xref ref-type="aff" rid="af49">49</xref></contrib><contrib contrib-type="author"><name><surname>Giovannucci</surname><given-names>Edward</given-names></name><xref ref-type="aff" rid="af42">42</xref><xref ref-type="aff" rid="af49">49</xref><xref ref-type="aff" rid="af43">43</xref></contrib><contrib contrib-type="author"><name><surname>Kraft</surname><given-names>Peter</given-names></name><xref ref-type="aff" rid="af42">42</xref><xref ref-type="aff" rid="af44">44</xref></contrib><contrib contrib-type="author"><name><surname>Huang</surname><given-names>Jinyan</given-names></name><xref ref-type="aff" rid="af42">42</xref></contrib><contrib contrib-type="author"><name><surname>Ma</surname><given-names>Baoshan</given-names></name><xref ref-type="aff" rid="af42">42</xref><xref ref-type="aff" rid="af85">85</xref></contrib><contrib contrib-type="author"><name><surname>Ye</surname><given-names>Yuanqing</given-names></name><xref ref-type="aff" rid="af37">37</xref></contrib><contrib contrib-type="author"><name><surname>Chiu</surname><given-names>Brian C.H.</given-names></name><xref ref-type="aff" rid="af86">86</xref></contrib><contrib contrib-type="author"><name><surname>Liang</surname><given-names>Liming</given-names></name><xref ref-type="aff" rid="af42">42</xref><xref ref-type="aff" rid="af44">44</xref></contrib><contrib contrib-type="author"><name><surname>Park</surname><given-names>Ju-Hyun</given-names></name><xref ref-type="aff" rid="af87">87</xref></contrib><contrib contrib-type="author"><name><surname>Chung</surname><given-names>Charles C.</given-names></name><xref ref-type="aff" rid="af1">1</xref></contrib><contrib contrib-type="author"><name><surname>Weisenburger</surname><given-names>Dennis D.</given-names></name><xref ref-type="aff" rid="af88">88</xref></contrib><contrib contrib-type="author"><name><surname>Fraumeni</surname><given-names>Joseph F.</given-names><suffix>Jr</suffix></name><xref ref-type="aff" rid="af1">1</xref></contrib><contrib contrib-type="author"><name><surname>Salles</surname><given-names>Gilles</given-names></name><xref ref-type="aff" rid="af20">20</xref><xref ref-type="aff" rid="af89">89</xref><xref ref-type="aff" rid="af90">90</xref></contrib><contrib contrib-type="author"><name><surname>Glenn</surname><given-names>Martha</given-names></name><xref ref-type="aff" rid="af9">9</xref></contrib><contrib contrib-type="author"><name><surname>Cannon-Albright</surname><given-names>Lisa</given-names></name><xref ref-type="aff" rid="af9">9</xref></contrib><contrib contrib-type="author"><name><surname>Curtin</surname><given-names>Karen</given-names></name><xref ref-type="aff" rid="af9">9</xref></contrib><contrib contrib-type="author"><name><surname>Wu</surname><given-names>Xifeng</given-names></name><xref ref-type="aff" rid="af37">37</xref><xref ref-type="author-notes" rid="AN2">‡</xref></contrib><contrib contrib-type="author"><name><surname>Smedby</surname><given-names>Karin E.</given-names></name><xref ref-type="aff" rid="af91">91</xref><xref ref-type="author-notes" rid="AN2">‡</xref></contrib><contrib contrib-type="author"><name><surname>de Sanjose</surname><given-names>Silvia</given-names></name><xref ref-type="aff" rid="af68">68</xref><xref ref-type="aff" rid="af69">69</xref><xref ref-type="author-notes" rid="AN2">‡</xref></contrib><contrib contrib-type="author"><name><surname>Skibola</surname><given-names>Christine F.</given-names></name><xref ref-type="aff" rid="af22">22</xref><xref ref-type="aff" rid="af24">24</xref><xref ref-type="author-notes" rid="AN2">‡</xref></contrib><contrib contrib-type="author"><name><surname>Berndt</surname><given-names>Sonja I.</given-names></name><xref ref-type="aff" rid="af1">1</xref><xref ref-type="author-notes" rid="AN2">‡</xref></contrib><contrib contrib-type="author"><name><surname>Birmann</surname><given-names>Brenda M.</given-names></name><xref ref-type="aff" rid="af49">49</xref><xref ref-type="author-notes" rid="AN2">‡</xref></contrib><contrib contrib-type="author"><name><surname>Chanock</surname><given-names>Stephen J.</given-names></name><xref ref-type="aff" rid="af1">1</xref><xref ref-type="author-notes" rid="AN2">‡</xref></contrib><contrib contrib-type="author"><name><surname>Rothman</surname><given-names>Nathaniel</given-names></name><xref ref-type="aff" rid="af1">1</xref><xref ref-type="author-notes" rid="AN2">‡</xref></contrib><aff id="af1"><label>1</label><addr-line>Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Bethesda, MD</addr-line>,<country>USA</country>,</aff><aff id="af2"><label>2</label><addr-line>Department of Health Sciences Research</addr-line>,</aff><aff id="af3"><label>3</label><addr-line>Department of Medicine</addr-line> and</aff><aff id="af4"><label>4</label><addr-line>Division of Biomedical Statistics and Informatics, Department of Health Sciences Research</addr-line>,<institution>Mayo Clinic</institution>,<addr-line>Rochester, MN</addr-line>,<institution>USA</institution>,</aff><aff id="af5"><label>5</label><addr-line>Institute for Risk Assessment Sciences</addr-line>,<institution>Utrecht University</institution>,<addr-line>Utrecht</addr-line>,<institution>The Netherlands</institution>,</aff><aff id="af6"><label>6</label><addr-line>Julius Center for Health Sciences and Primary Care</addr-line> and</aff><aff id="af7"><label>7</label><addr-line>Department of Medical Genetics and of Epidemiology</addr-line>,<institution>University Medical Center Utrecht</institution>,<addr-line>Utrecht</addr-line>,<country>The Netherlands</country>,</aff><aff id="af8"><label>8</label><addr-line>Epidemiology Research Program</addr-line>,<institution>American Cancer Society</institution>,<addr-line>Atlanta, GA</addr-line>,<country>USA</country>,</aff><aff id="af9"><label>9</label><addr-line>Department of Internal Medicine</addr-line>,<institution>University of Utah School of Medicine</institution>,<addr-line>Salt Lake City, UT</addr-line>,<institution>USA</institution>,</aff><aff id="af10"><label>10</label><addr-line>Cancer Control Research</addr-line> and</aff><aff id="af11"><label>11</label><addr-line>Genome Sciences Centre</addr-line>,<institution>BC Cancer Agency</institution>,<addr-line>Vancouver, BC</addr-line>,<country>Canada</country>,</aff><aff id="af12"><label>12</label><addr-line>School of Population and Public Health</addr-line>,<institution>University of British Columbia</institution>,<addr-line>Vancouver, BC</addr-line>,<country>Canada</country>,</aff><aff id="af13"><label>13</label><addr-line>Division of Cancer Etiology</addr-line>,<institution>City of Hope Beckman Research Institute</institution>,<addr-line>Duarte, CA</addr-line>,<institution>USA</institution>,</aff><aff id="af14"><label>14</label><addr-line>Center for Chronic Immunodeficiency</addr-line>,<institution>University Medical Center Freiburg</institution>,<addr-line>Freiburg, Baden-Württemberg</addr-line>,<country>Germany</country>,</aff><aff id="af15"><label>15</label><addr-line>Department of Medicine</addr-line> and</aff><aff id="af16"><label>16</label><addr-line>Departments of Laboratory Medicine and Pathology</addr-line>,<institution>Memorial Sloan Kettering Cancer Center</institution>,<addr-line>New York, NY</addr-line>,<country>USA</country>,</aff><aff id="af17"><label>17</label><addr-line>Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics</addr-line>,<institution>National Cancer Institute</institution>,<addr-line>Gaithersburg, MD</addr-line>,<country>USA</country>,</aff><aff id="af18"><label>18</label><addr-line>Department of Hematology</addr-line> and</aff><aff id="af19"><label>19</label><addr-line>INSERM U1052, Cancer Research Center of Lyon</addr-line>,<institution>Centre Léon Bérard</institution>,<addr-line>Lyon</addr-line>,<country>France</country>,</aff><aff id="af20"><label>20</label><addr-line>Laboratoire de Biologie Moléculaire de la Cellule UMR 5239</addr-line>,<institution>Centre National de la Recherche Scientifique</institution>,<addr-line>Pierre benite Cedex</addr-line>,<institution>France</institution>,</aff><aff id="af21"><label>21</label><institution>International Agency for Research on Cancer (IARC)</institution>,<addr-line>Lyon</addr-line>,<country>France</country>,</aff><aff id="af22"><label>22</label><addr-line>Department of Epidemiology, School of Public Health and Comprehensive Cancer Center</addr-line> and</aff><aff id="af23"><label>23</label><addr-line>Department of Biostatistics</addr-line>,<institution>University of Alabama at Birmingham</institution>,<addr-line>Birmingham, AL</addr-line>,<country>USA</country>,</aff><aff id="af24"><label>24</label><addr-line>Division of Environmental Health Sciences</addr-line>,<institution>University of California Berkeley School of Public Health</institution>,<addr-line>Berkeley, CA</addr-line>,<country>USA</country>,</aff><aff id="af25"><label>25</label><addr-line>Epidemiology of Childhood and Adolescent Cancers Group, INSERM</addr-line>,<institution>Center of Research in Epidemiology and Statistics Sorbonne Paris Cité (CRESS)</institution>,<addr-line>Paris</addr-line>,<country>France</country>,</aff><aff id="af26"><label>26</label><institution>Université Paris Descartes</institution>,<addr-line>Paris</addr-line>,<country>France</country>,</aff><aff id="af27"><label>27</label><addr-line>Registre des hémopathies malignes de la Gironde</addr-line>,<institution>Institut Bergonié</institution>,<addr-line>Bordeaux Cedex</addr-line>,<institution>France</institution>,</aff><aff id="af28"><label>28</label><addr-line>Winship Cancer Institute</addr-line>,<institution>Emory University School of Medicine</institution>,<addr-line>Atlanta, GA</addr-line>,<country>USA</country>,</aff><aff id="af29"><label>29</label><addr-line>Department of Environmental and Occupational Health</addr-line>,<institution>Drexel University School of Public Health</institution>,<addr-line>Philadelphia, PA</addr-line>,<country>USA</country>,</aff><aff id="af30"><label>30</label><addr-line>Division of Public Health Sciences</addr-line>,<institution>Fred Hutchinson Cancer Research Center</institution>,<addr-line>Seattle, WA</addr-line>,<institution>USA</institution>,</aff><aff id="af31"><label>31</label><addr-line>Department of Biomedical Physiology and Kinesiology</addr-line>,<institution>Simon Fraser University</institution>,<addr-line>Burnaby, BC</addr-line>,<institution>Canada</institution>,</aff><aff id="af32"><label>32</label><addr-line>Cancer Epidemiology Centre</addr-line>,<institution>Cancer Council Victoria</institution>,<addr-line>Melbourne, VIC</addr-line>,<institution>Australia</institution>,</aff><aff id="af33"><label>33</label><addr-line>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health</addr-line> and</aff><aff id="af34"><label>34</label><addr-line>Genetic Epidemiology Laboratory, Department of Pathology</addr-line>,<institution>University of Melbourne</institution>,<addr-line>Melbourne, VIC</addr-line>,<country>Australia</country>,</aff><aff id="af35"><label>35</label><addr-line>Department of Epidemiology Research, Division of Health Surveillance and Research</addr-line>,<institution>Statens Serum Institut</institution>,<addr-line>Copenhagen</addr-line>,<country>Denmark</country>,</aff><aff id="af36"><label>36</label><addr-line>Department of Medicine</addr-line>,<institution>Stanford University School of Medicine</institution>,<addr-line>Stanford, CA</addr-line>,<country>USA</country>,</aff><aff id="af37"><label>37</label><addr-line>Department of Epidemiology</addr-line>,<institution>MD Anderson Cancer Center</institution>,<addr-line>Houston, TX</addr-line>,<country>USA</country>,</aff><aff id="af38"><label>38</label><addr-line>Division of Endocrinology, Diabetes and Metabolism</addr-line>,<institution>The Ohio State University</institution>,<addr-line>Columbus, OH</addr-line>,<country>USA</country>,</aff><aff id="af39"><label>39</label><addr-line>Department of Health Sciences</addr-line>,<institution>University of York</institution>,<addr-line>York</addr-line>,<country>UK</country>,</aff><aff id="af40"><label>40</label><addr-line>Ontario Health Study, Toronto, ON</addr-line>,<institution>Canada</institution>,</aff><aff id="af41"><label>41</label><addr-line>Centre for Big Data Research in Health</addr-line>,<institution>University of New South Wales</institution>,<addr-line>Sydney, NSW</addr-line>,<country>Australia</country>,</aff><aff id="af42"><label>42</label><addr-line>Department of Epidemiology</addr-line>,</aff><aff id="af43"><label>43</label><addr-line>Department of Nutrition</addr-line> and</aff><aff id="af44"><label>44</label><addr-line>Department of Biostatistics</addr-line>,<institution>Harvard School of Public Health</institution>,<addr-line>Boston, MA</addr-line>,<institution>USA</institution>,</aff><aff id="af45"><label>45</label><addr-line>MRC-PHE Centre for Environment and Health, School of Public Health</addr-line> and</aff><aff id="af46"><label>46</label><addr-line>School of Public Health</addr-line>,<institution>Imperial College London</institution>,<addr-line>London</addr-line>,<country>UK</country>,</aff><aff id="af47"><label>47</label><addr-line>Department of Biomedical Science</addr-line> and</aff><aff id="af48"><label>48</label><addr-line>Department of Public Health, Clinical and Molecular Medicine</addr-line>,<institution>University of Cagliari</institution>,<addr-line>Monserrato, Cagliari</addr-line>,<country>Italy</country>,</aff><aff id="af49"><label>49</label><addr-line>Channing Division of Network Medicine, Department of Medicine</addr-line>,<institution>Brigham and Women's Hospital and Harvard Medical School</institution>,<addr-line>Boston, MA</addr-line>,<country>USA</country>,</aff><aff id="af50"><label>50</label><addr-line>Department of Population Health</addr-line> and</aff><aff id="af51"><label>51</label><addr-line>Department of Environmental Medicine</addr-line>,<institution>New York University School of Medicine</institution>,<addr-line>New York, NY</addr-line>,<institution>USA</institution>,</aff><aff id="af52"><label>52</label><addr-line>Perlmutter Cancer Center</addr-line>,<institution>NYU Langone Medical Center</institution>,<addr-line>New York, NY</addr-line>,<country>USA</country>,</aff><aff id="af53"><label>53</label><institution>Westat</institution>,<addr-line>Rockville, MD</addr-line>,<country>USA</country>,</aff><aff id="af54"><label>54</label><addr-line>Department of Internal Medicine, Carver College of Medicine</addr-line>,<institution>The University of Iowa</institution>,<addr-line>Iowa City, IA</addr-line>,<country>USA</country>,</aff><aff id="af55"><label>55</label><addr-line>Centre Heni Becquerel</addr-line>,<institution>Université de Rouen</institution>,<addr-line>Rouen</addr-line>,<country>France</country>,</aff><aff id="af56"><label>56</label><addr-line>Lymphoid Malignancies Unit</addr-line>,<institution>Henri Mondor Hospital and University Paris Est</institution>,<addr-line>Créteil</addr-line>,<country>France</country>,</aff><aff id="af57"><label>57</label><addr-line>Department of Pathology, AP-HP, Necker Enfants malades</addr-line>,<institution>Université Paris Descartes</institution>,<addr-line>Sorbonne Paris Cité</addr-line>,<country>France</country>,</aff><aff id="af58"><label>58</label><addr-line>Department of Immunology, Genetics and Pathology</addr-line>,<institution>Uppsala University</institution>,<addr-line>Uppsala</addr-line>,<country>Sweden</country>,</aff><aff id="af59"><label>59</label><addr-line>Department of Medical Epidemiology and Biostatistics</addr-line>,<institution>Karolinska Institutet</institution>,<addr-line>Stockholm</addr-line>,<country>Sweden</country>,</aff><aff id="af60"><label>60</label><addr-line>Department of Medical Biosciences</addr-line>,<institution>Umeå University</institution>,<addr-line>Umeå</addr-line>,<country>Sweden</country>,</aff><aff id="af61"><label>61</label><addr-line>Department of Epidemiology and Biostatistics</addr-line>,<institution>University of California San Francisco</institution>,<addr-line>San Francisco, CA</addr-line>,<country>USA</country>,</aff><aff id="af62"><label>62</label><addr-line>Department of Preventive Medicine</addr-line> and</aff><aff id="af63"><label>63</label><addr-line>Norris Comprehensive Cancer Center, USC Keck School of Medicine</addr-line>,<institution>University of Southern California</institution>,<addr-line>Los Angeles, CA</addr-line>,<country>USA</country>,</aff><aff id="af64"><label>64</label><addr-line>Department of Family Medicine and Public Health Sciences</addr-line>,<institution>Wayne State University</institution>,<addr-line>Detroit, MI</addr-line>,<country>USA</country>,</aff><aff id="af65"><label>65</label><addr-line>Department of Epidemiology</addr-line> and</aff><aff id="af66"><label>66</label><addr-line>Carolina Center for Genome Sciences</addr-line>,<institution>University of North Carolina at Chapel Hill</institution>,<addr-line>Chapel Hill, NC</addr-line>,<country>USA</country>,</aff><aff id="af67"><label>67</label><addr-line>Division of Cancer Epidemiology</addr-line>,<institution>German Cancer Research Center (DKFZ)</institution>,<addr-line>Heidelberg, Baden-Württemberg</addr-line>,<institution>Germany</institution>,</aff><aff id="af68"><label>68</label><addr-line>Cancer Epidemiology Research Programme, Catalan Institute of Oncology-IDIBELL</addr-line>,<institution>L'Hospitalet de Llobregat</institution>,<addr-line>Barcelona</addr-line>,<country>Spain</country>,</aff><aff id="af69"><label>69</label><institution>CIBER de Epidemiología y Salud Pública (CIBERESP)</institution>,<addr-line>Barcelona</addr-line>,<institution>Spain</institution>,</aff><aff id="af70"><label>70</label><addr-line>The Tisch Cancer Institute</addr-line> and</aff><aff id="af71"><label>71</label><addr-line>Icahn Institute for Genomics and Multiscale Biology, Department of Genetics and Genomic Sciences</addr-line>,<institution>Icahn School of Medicine at Mount Sinai</institution>,<addr-line>New York, NY</addr-line>,<country>USA</country>,</aff><aff id="af72"><label>72</label><addr-line>Department of Cancer Epidemiology and Genetics</addr-line>,<institution>Masaryk Memorial Cancer Institute and MF MU</institution>,<addr-line>Brno</addr-line>,<country>Czech Republic</country>,</aff><aff id="af73"><label>73</label><addr-line>EA 4184, Registre des Hémopathies Malignes de Côte d'Or</addr-line>,<institution>University of Burgundy and Dijon University Hospital</institution>,<addr-line>Dijon</addr-line>,<country>France</country>,</aff><aff id="af74"><label>74</label><addr-line>School of Nursing and Human Sciences</addr-line>,<institution>Dublin City University</institution>,<addr-line>Dublin</addr-line>,<institution>Ireland</institution>,</aff><aff id="af75"><label>75</label><addr-line>Department of Environmental Health Sciences</addr-line> and</aff><aff id="af76"><label>76</label><addr-line>Department of Biostatistics</addr-line>,<institution>Yale School of Public Health</institution>,<addr-line>New Haven, CT</addr-line>,<country>USA</country>,</aff><aff id="af77"><label>77</label><addr-line>Faculty of Medicine and Health Sciences</addr-line>,<institution>Macquarie University</institution>,<addr-line>Sydney, NSW</addr-line>,<country>Australia</country>,</aff><aff id="af78"><label>78</label><addr-line>Department of Histopathology</addr-line>,<institution>Douglass Hanly Moir Pathology</institution>,<addr-line>Sydney, NSW</addr-line>,<country>Australia</country>,</aff><aff id="af79"><label>79</label><addr-line>Chronic Disease Prevention Unit</addr-line>,<institution>National Institute for Health and Welfare</institution>,<addr-line>Helsinki</addr-line>,<country>Finland</country>,</aff><aff id="af80"><label>80</label><addr-line>Human Genetics Foundation, Turin</addr-line>,<country>Italy</country>,</aff><aff id="af81"><label>81</label><addr-line>Department of Epidemiology</addr-line>,<institution>German Institute for Human Nutrition</institution>,<addr-line>Potsdam</addr-line>,<country>Germany</country>,</aff><aff id="af82"><label>82</label><addr-line>Danish Cancer Society Research Center, Copenhagen</addr-line>,<country>Denmark</country>,</aff><aff id="af83"><label>83</label><addr-line>Hematology Unit</addr-line>,<institution>Ospedale Oncologico di Riferimento Regionale A. Businco</institution>,<addr-line>Cagliari</addr-line>,<country>Italy</country>,</aff><aff id="af84"><label>84</label><addr-line>Department of Surgery and Translational Medicine, Section of Anatomo-Pathology</addr-line>,<institution>University of Florence</institution>,<addr-line>Florence</addr-line>,<country>Italy</country>,</aff><aff id="af85"><label>85</label><addr-line>College of Information Science and Technology</addr-line>,<institution>Dalian Maritime University</institution>,<addr-line>Dalian, Liaoning Province</addr-line>,<country>China</country>,</aff><aff id="af86"><label>86</label><addr-line>Department of Health Studies</addr-line>,<institution>University of Chicago</institution>,<addr-line>Chicago, IL</addr-line>,<country>USA</country>,</aff><aff id="af87"><label>87</label><addr-line>Department of Statistics</addr-line>,<institution>Dongguk University</institution>,<addr-line>Seoul</addr-line>,<country>Republic of Korea</country>,</aff><aff id="af88"><label>88</label><addr-line>Department of Pathology</addr-line>,<institution>City of Hope National Medical Center</institution>,<addr-line>Duarte, CA</addr-line>,<country>USA</country>,</aff><aff id="af89"><label>89</label><addr-line>Department of Hematology</addr-line>,<institution>Hospices Civils de Lyon</institution>,<addr-line>Pierre benite Cedex</addr-line>,<country>France</country>,</aff><aff id="af90"><label>90</label><addr-line>Department of Hematology</addr-line>,<institution>Université Lyon-1</institution>,<addr-line>Pierre benite Cedex</addr-line>,<country>France</country> and</aff><aff id="af91"><label>91</label><addr-line>Department of Medicine, Solna</addr-line>,<institution>Karolinska Institutet, Karolinska University Hospital</institution>,<addr-line>Stockholm</addr-line>,<country>Sweden</country></aff></contrib-group><author-notes><corresp id="cor1"><label>*</label>To whom correspondence should be addressed at: 8717 Grovemont Circle, Bethesda, MD 20892-9776, USA. Tel: +1 301 435 6391; Fax: +1 301 402 3134; Email: <email>mitchell.machiela@nih.gov</email></corresp><fn fn-type="con" id="AN1"><label>†</label><p>These authors contributed equally to this work.</p></fn><fn fn-type="con" id="AN2"><label>‡</label><p>These authors jointly directed this work.</p></fn></author-notes><pub-date pub-type="ppub"><day>15</day><month>4</month><year>2016</year></pub-date><pub-date pub-type="epub"><day>09</day><month>2</month><year>2016</year></pub-date><volume>25</volume><issue>8</issue><fpage>1663</fpage><lpage>1676</lpage><history><date date-type="received"><day>16</day><month>9</month><year>2015</year></date><date date-type="rev-recd"><day>6</day><month>1</month><year>2016</year></date><date date-type="accepted"><day>27</day><month>1</month><year>2016</year></date></history><permissions><copyright-statement>Published by Oxford University Press 2016. This work is written by (a) US Government employee(s) and is in the public domain in the US.</copyright-statement><copyright-year>2016</copyright-year></permissions><self-uri content-type="pdf" xlink:href="ddw027.pdf"></self-uri><abstract><p>Evidence from a small number of studies suggests that longer telomere length measured in peripheral leukocytes is associated with an increased risk of non-Hodgkin lymphoma (NHL). However, these studies may be biased by reverse causation, confounded by unmeasured environmental exposures and might miss time points for which prospective telomere measurement would best reveal a relationship between telomere length and NHL risk. We performed an analysis of genetically inferred telomere length and NHL risk in a study of 10 102 NHL cases of the four most common B-cell histologic types and 9562 controls using a genetic risk score (GRS) comprising nine telomere length-associated single-nucleotide polymorphisms. This approach uses existing genotype data and estimates telomere length by weighing the number of telomere length-associated variant alleles an individual carries with the published change in kb of telomere length. The analysis of the telomere length GRS resulted in an association between longer telomere length and increased NHL risk [four B-cell histologic types combined; odds ratio (OR) = 1.49, 95% CI 1.22–1.82, <italic>P</italic>-value = 8.5 × 10<sup>−5</sup>]. Subtype-specific analyses indicated that chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL/SLL) was the principal NHL subtype contributing to this association (OR = 2.60, 95% CI 1.93–3.51, <italic>P</italic>-value = 4.0 × 10<sup>−10</sup>). Significant interactions were observed across strata of sex for CLL/SLL and marginal zone lymphoma subtypes as well as age for the follicular lymphoma subtype. Our results indicate that a genetic background that favors longer telomere length may increase NHL risk, particularly risk of CLL/SLL, and are consistent with earlier studies relating longer telomere length with increased NHL risk.</p></abstract></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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