Selectivity of voluntary finger flexion during ischemic nerve block of the hand
Identifieur interne : 002923 ( Pmc/Checkpoint ); précédent : 002922; suivant : 002924Selectivity of voluntary finger flexion during ischemic nerve block of the hand
Auteurs : Karen T. Reilly [France] ; Marc H. Schieber [États-Unis] ; Penelope A. Mcnulty [Australie]Source :
- Experimental brain research. Experimentelle Hirnforschung. Experimentation cerebrale [ 0014-4819 ] ; 2008.
Abstract
During ischemic nerve block of an extremity, the cortical representations of muscles proximal to the block are known to expand, increasing the overlap of different muscle representations. Such reorganization mimics that seen in actual amputees. We investigated whether such changes degrade voluntary control of muscles proximal to the block. Nine subjects produced brief, isometric flexion force selectively with each fingertip before, during, and after ischemic block at the wrist. We recorded the isometric force exerted at the distal phalanx of each digit, along with electromyographic (EMG) activity from intrinsic and extrinsic finger muscles. Despite paralysis of the intrinsic hand muscles, and associated decrements in the flexion forces exerted by the thumb, index, and little fingers, the selectivity of voluntary finger flexion forces and of EMG activity in the extrinsic finger muscles that generated these forces remained unchanged. Our observations indicate that during ischemic nerve block, reorganization does not eliminate or degrade motor representations of the temporarily deafferented and paralyzed fingers.
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DOI: 10.1007/s00221-008-1368-y
PubMed: 18431564
PubMed Central: 2712613
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Experimentelle Hirnforschung. Experimentation cerebrale</title><idno type="ISSN">0014-4819</idno><idno type="eISSN">1432-1106</idno><imprint><date when="2008">2008</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">During ischemic nerve block of an extremity, the cortical representations of muscles proximal to the block are known to expand, increasing the overlap of different muscle representations. Such reorganization mimics that seen in actual amputees. We investigated whether such changes degrade voluntary control of muscles proximal to the block. Nine subjects produced brief, isometric flexion force selectively with each fingertip before, during, and after ischemic block at the wrist. We recorded the isometric force exerted at the distal phalanx of each digit, along with electromyographic (EMG) activity from intrinsic and extrinsic finger muscles. Despite paralysis of the intrinsic hand muscles, and associated decrements in the flexion forces exerted by the thumb, index, and little fingers, the selectivity of voluntary finger flexion forces and of EMG activity in the extrinsic finger muscles that generated these forces remained unchanged. Our observations indicate that during ischemic nerve block, reorganization does not eliminate or degrade motor representations of the temporarily deafferented and paralyzed fingers.</p></div></front></TEI><pmc article-type="research-article" xml:lang="EN"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
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<front><journal-meta><journal-id journal-id-type="nlm-journal-id">0043312</journal-id><journal-id journal-id-type="pubmed-jr-id">3641</journal-id><journal-id journal-id-type="nlm-ta">Exp Brain Res</journal-id><journal-title>Experimental brain research. Experimentelle Hirnforschung. Experimentation cerebrale</journal-title><issn pub-type="ppub">0014-4819</issn><issn pub-type="epub">1432-1106</issn></journal-meta><article-meta><article-id pub-id-type="pmid">18431564</article-id><article-id pub-id-type="pmc">2712613</article-id><article-id pub-id-type="doi">10.1007/s00221-008-1368-y</article-id><article-id pub-id-type="manuscript">NIHMS114585</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Selectivity of voluntary finger flexion during ischemic nerve block of the hand</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Reilly</surname><given-names>Karen T.</given-names></name><xref rid="A1" ref-type="aff">1</xref><xref rid="A2" ref-type="aff">2</xref></contrib><contrib contrib-type="author"><name><surname>Schieber</surname><given-names>Marc H.</given-names></name><xref rid="A3" ref-type="aff">3</xref></contrib><contrib contrib-type="author"><name><surname>McNulty</surname><given-names>Penelope A.</given-names></name><xref rid="A4" ref-type="aff">4</xref></contrib></contrib-group><aff id="A1"><label>1</label> Center for Cognitive Neuroscience, CNRS, 67 boulevard Pinel, Bron 69675, FRANCE</aff><aff id="A2"><label>2</label> Université Claude Bernard Lyon 1, Lyon, FRANCE</aff><aff id="A3"><label>3</label> Departments of Neurology and of Neurobiology & Anatomy University of Rochester, Rochester, NY, 14642, USA</aff><aff id="A4"><label>4</label> Prince of Wales Medical Research Institute, Randwick, NSW 2031, AUSTRALIA</aff><author-notes><corresp id="FN1">Correspondence to: Dr. Karen Reilly, Centre for Cognitive Neuroscience, CNRS, 67 boulevard Pinel, Bron 69675, FRANCE, <email>kreilly@isc.cnrs.fr</email></corresp></author-notes><pub-date pub-type="nihms-submitted"><day>4</day><month>5</month><year>2009</year></pub-date><pub-date pub-type="epub"><day>23</day><month>4</month><year>2008</year></pub-date><pub-date pub-type="ppub"><month>7</month><year>2008</year></pub-date><pub-date pub-type="pmc-release"><day>18</day><month>7</month><year>2009</year></pub-date><volume>188</volume><issue>3</issue><fpage>385</fpage><lpage>397</lpage><abstract><p id="P1">During ischemic nerve block of an extremity, the cortical representations of muscles proximal to the block are known to expand, increasing the overlap of different muscle representations. Such reorganization mimics that seen in actual amputees. We investigated whether such changes degrade voluntary control of muscles proximal to the block. Nine subjects produced brief, isometric flexion force selectively with each fingertip before, during, and after ischemic block at the wrist. We recorded the isometric force exerted at the distal phalanx of each digit, along with electromyographic (EMG) activity from intrinsic and extrinsic finger muscles. Despite paralysis of the intrinsic hand muscles, and associated decrements in the flexion forces exerted by the thumb, index, and little fingers, the selectivity of voluntary finger flexion forces and of EMG activity in the extrinsic finger muscles that generated these forces remained unchanged. Our observations indicate that during ischemic nerve block, reorganization does not eliminate or degrade motor representations of the temporarily deafferented and paralyzed fingers.</p></abstract><kwd-group><kwd>amputation</kwd><kwd>ischemic nerve block</kwd><kwd>hand</kwd><kwd>finger</kwd><kwd>motor cortex</kwd><kwd>electromyography</kwd></kwd-group><contract-num rid="NS1">R37 NS027686-19</contract-num><contract-sponsor id="NS1">National Institute of Neurological Disorders and Stroke : NINDS</contract-sponsor></article-meta></front></pmc><affiliations><list><country><li>Australie</li><li>France</li><li>États-Unis</li></country><region><li>Auvergne-Rhône-Alpes</li><li>Rhône-Alpes</li></region><settlement><li>Lyon</li></settlement></list><tree><country name="France"><region name="Auvergne-Rhône-Alpes"><name sortKey="Reilly, Karen T" sort="Reilly, Karen T" uniqKey="Reilly K" first="Karen T." last="Reilly">Karen T. Reilly</name></region><name sortKey="Reilly, Karen T" sort="Reilly, Karen T" uniqKey="Reilly K" first="Karen T." last="Reilly">Karen T. Reilly</name></country><country name="États-Unis"><noRegion><name sortKey="Schieber, Marc H" sort="Schieber, Marc H" uniqKey="Schieber M" first="Marc H." last="Schieber">Marc H. Schieber</name></noRegion></country><country name="Australie"><noRegion><name sortKey="Mcnulty, Penelope A" sort="Mcnulty, Penelope A" uniqKey="Mcnulty P" first="Penelope A." last="Mcnulty">Penelope A. Mcnulty</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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