V-ATPase-activity in the TGN/EE is required for exocytosis and recycling in Arabidopsis
Identifieur interne : 000C49 ( Pmc/Checkpoint ); précédent : 000C48; suivant : 000C50V-ATPase-activity in the TGN/EE is required for exocytosis and recycling in Arabidopsis
Auteurs : Yu Luo [Belgique] ; Stefan Scholl [Allemagne] ; Anett Doering [Allemagne] ; Yi Zhang [Allemagne] ; Niloufer G. Irani [Belgique] ; Simone Di Rubbo [Belgique] ; Lutz Neumetzler [Allemagne] ; Praveen Krishnamoorthy [Allemagne] ; Isabelle Van Houtte [Belgique] ; Evelien Mylle [Belgique] ; Volker Bischoff [France] ; Samantha Vernhettes [France] ; Johan Winne [Belgique] ; Ji Friml [Autriche] ; York-Dieter Stierhof [Allemagne] ; Karin Schumacher [Allemagne] ; Staffan Persson [Allemagne, Australie] ; Eugenia Russinova [Belgique]Source :
- Nature plants [ 2055-0278 ] ; 2015.
Abstract
In plants, vacuolar H+-ATPase (V-ATPase) activity acidifies both the trans-Golgi network/early endosome (TGN/EE) and the vacuole. This dual V-ATPase function has impeded our understanding in how the pH homeostasis within the plant TGN/EE controls exo- and endocytosis. Here, we show that the weak V-ATPase mutant
Url:
DOI: 10.1038/nplants.2015.94
PubMed: 27250258
PubMed Central: 4905525
Affiliations:
- Allemagne, Australie, Autriche, Belgique, France
- Bade-Wurtemberg, Brandebourg, District de Karlsruhe, Province de Flandre-Orientale, Région flamande, Victoria (État)
- Gand, Heidelberg, Melbourne, Potsdam
- Université de Gand, Université de Melbourne
Links toward previous steps (curation, corpus...)
Links to Exploration step
PMC:4905525Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">V-ATPase-activity in the TGN/EE is required for exocytosis and recycling in <italic>Arabidopsis</italic></title><author><name sortKey="Luo, Yu" sort="Luo, Yu" uniqKey="Luo Y" first="Yu" last="Luo">Yu Luo</name><affiliation wicri:level="4"><nlm:aff id="A1">Department of Plant Systems Biology, VIB, 9052 Gent, Belgium; Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Gent, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Plant Systems Biology, VIB, 9052 Gent, Belgium; Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Gent</wicri:regionArea><orgName type="university">Université de Gand</orgName><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Scholl, Stefan" sort="Scholl, Stefan" uniqKey="Scholl S" first="Stefan" last="Scholl">Stefan Scholl</name><affiliation wicri:level="3"><nlm:aff id="A2">Developmental Biology of Plants, Centre for Organismal Studies (COS), Heidelberg University, 69120 Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Developmental Biology of Plants, Centre for Organismal Studies (COS), Heidelberg University, 69120 Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Doering, Anett" sort="Doering, Anett" uniqKey="Doering A" first="Anett" last="Doering">Anett Doering</name><affiliation wicri:level="3"><nlm:aff id="A3">Max-Planck Institute for Molecular Plant Physiology, 14476 Potsdam, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Max-Planck Institute for Molecular Plant Physiology, 14476 Potsdam</wicri:regionArea><placeName><region type="land" nuts="2">Brandebourg</region><settlement type="city">Potsdam</settlement></placeName></affiliation></author><author><name sortKey="Zhang, Yi" sort="Zhang, Yi" uniqKey="Zhang Y" first="Yi" last="Zhang">Yi Zhang</name><affiliation wicri:level="3"><nlm:aff id="A3">Max-Planck Institute for Molecular Plant Physiology, 14476 Potsdam, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Max-Planck Institute for Molecular Plant Physiology, 14476 Potsdam</wicri:regionArea><placeName><region type="land" nuts="2">Brandebourg</region><settlement type="city">Potsdam</settlement></placeName></affiliation></author><author><name sortKey="Irani, Niloufer G" sort="Irani, Niloufer G" uniqKey="Irani N" first="Niloufer G." last="Irani">Niloufer G. Irani</name><affiliation wicri:level="4"><nlm:aff id="A1">Department of Plant Systems Biology, VIB, 9052 Gent, Belgium; Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Gent, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Plant Systems Biology, VIB, 9052 Gent, Belgium; Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Gent</wicri:regionArea><orgName type="university">Université de Gand</orgName><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Rubbo, Simone Di" sort="Rubbo, Simone Di" uniqKey="Rubbo S" first="Simone Di" last="Rubbo">Simone Di Rubbo</name><affiliation wicri:level="4"><nlm:aff id="A1">Department of Plant Systems Biology, VIB, 9052 Gent, Belgium; Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Gent, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Plant Systems Biology, VIB, 9052 Gent, Belgium; Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Gent</wicri:regionArea><orgName type="university">Université de Gand</orgName><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Neumetzler, Lutz" sort="Neumetzler, Lutz" uniqKey="Neumetzler L" first="Lutz" last="Neumetzler">Lutz Neumetzler</name><affiliation wicri:level="3"><nlm:aff id="A3">Max-Planck Institute for Molecular Plant Physiology, 14476 Potsdam, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Max-Planck Institute for Molecular Plant Physiology, 14476 Potsdam</wicri:regionArea><placeName><region type="land" nuts="2">Brandebourg</region><settlement type="city">Potsdam</settlement></placeName></affiliation></author><author><name sortKey="Krishnamoorthy, Praveen" sort="Krishnamoorthy, Praveen" uniqKey="Krishnamoorthy P" first="Praveen" last="Krishnamoorthy">Praveen Krishnamoorthy</name><affiliation wicri:level="3"><nlm:aff id="A3">Max-Planck Institute for Molecular Plant Physiology, 14476 Potsdam, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Max-Planck Institute for Molecular Plant Physiology, 14476 Potsdam</wicri:regionArea><placeName><region type="land" nuts="2">Brandebourg</region><settlement type="city">Potsdam</settlement></placeName></affiliation></author><author><name sortKey="Van Houtte, Isabelle" sort="Van Houtte, Isabelle" uniqKey="Van Houtte I" first="Isabelle" last="Van Houtte">Isabelle Van Houtte</name><affiliation wicri:level="4"><nlm:aff id="A1">Department of Plant Systems Biology, VIB, 9052 Gent, Belgium; Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Gent, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Plant Systems Biology, VIB, 9052 Gent, Belgium; Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Gent</wicri:regionArea><orgName type="university">Université de Gand</orgName><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Mylle, Evelien" sort="Mylle, Evelien" uniqKey="Mylle E" first="Evelien" last="Mylle">Evelien Mylle</name><affiliation wicri:level="4"><nlm:aff id="A1">Department of Plant Systems Biology, VIB, 9052 Gent, Belgium; Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Gent, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Plant Systems Biology, VIB, 9052 Gent, Belgium; Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Gent</wicri:regionArea><orgName type="university">Université de Gand</orgName><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Bischoff, Volker" sort="Bischoff, Volker" uniqKey="Bischoff V" first="Volker" last="Bischoff">Volker Bischoff</name><affiliation wicri:level="1"><nlm:aff id="A4">Institut National de la Recherche Agronomique, Unité Mixte de Recherche 1318, Institut Jean-Pierre Bourgin, Saclay Plant Sciences, 78000 Versailles, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Institut National de la Recherche Agronomique, Unité Mixte de Recherche 1318, Institut Jean-Pierre Bourgin, Saclay Plant Sciences, 78000 Versailles</wicri:regionArea><wicri:noRegion>78000 Versailles</wicri:noRegion><wicri:noRegion>78000 Versailles</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A5">AgroParisTech,Institut Jean-Pierre Bourgin, 78000 Versailles, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>AgroParisTech,Institut Jean-Pierre Bourgin, 78000 Versailles</wicri:regionArea><wicri:noRegion>78000 Versailles</wicri:noRegion><wicri:noRegion>78000 Versailles</wicri:noRegion></affiliation></author><author><name sortKey="Vernhettes, Samantha" sort="Vernhettes, Samantha" uniqKey="Vernhettes S" first="Samantha" last="Vernhettes">Samantha Vernhettes</name><affiliation wicri:level="1"><nlm:aff id="A4">Institut National de la Recherche Agronomique, Unité Mixte de Recherche 1318, Institut Jean-Pierre Bourgin, Saclay Plant Sciences, 78000 Versailles, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Institut National de la Recherche Agronomique, Unité Mixte de Recherche 1318, Institut Jean-Pierre Bourgin, Saclay Plant Sciences, 78000 Versailles</wicri:regionArea><wicri:noRegion>78000 Versailles</wicri:noRegion><wicri:noRegion>78000 Versailles</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A5">AgroParisTech,Institut Jean-Pierre Bourgin, 78000 Versailles, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>AgroParisTech,Institut Jean-Pierre Bourgin, 78000 Versailles</wicri:regionArea><wicri:noRegion>78000 Versailles</wicri:noRegion><wicri:noRegion>78000 Versailles</wicri:noRegion></affiliation></author><author><name sortKey="Winne, Johan" sort="Winne, Johan" uniqKey="Winne J" first="Johan" last="Winne">Johan Winne</name><affiliation wicri:level="4"><nlm:aff id="A6">Department of Organic Chemistry, Polymer Chemistry Research Group and Laboratory for Organic Synthesis, Ghent University, 9000 Gent, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Organic Chemistry, Polymer Chemistry Research Group and Laboratory for Organic Synthesis, Ghent University, 9000 Gent</wicri:regionArea><placeName><region type="province" nuts="2">Province de Flandre-Orientale</region><settlement type="city">Gand</settlement><settlement type="city">Gand</settlement></placeName><orgName type="university">Université de Gand</orgName></affiliation></author><author><name sortKey="Friml, Ji" sort="Friml, Ji" uniqKey="Friml J" first="Ji" last="Friml">Ji Friml</name><affiliation wicri:level="1"><nlm:aff id="A7">Institute of Science and Technology Austria (IST Austria), 3400 Klosterneuburg, Austria</nlm:aff><country xml:lang="fr">Autriche</country><wicri:regionArea>Institute of Science and Technology Austria (IST Austria), 3400 Klosterneuburg</wicri:regionArea><wicri:noRegion>3400 Klosterneuburg</wicri:noRegion></affiliation></author><author><name sortKey="Stierhof, York Dieter" sort="Stierhof, York Dieter" uniqKey="Stierhof Y" first="York-Dieter" last="Stierhof">York-Dieter Stierhof</name><affiliation wicri:level="1"><nlm:aff id="A8">Center for Plant Molecular Biology (ZMBP), University of Tübingen, 72076 Tübingen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Center for Plant Molecular Biology (ZMBP), University of Tübingen, 72076 Tübingen</wicri:regionArea><wicri:noRegion>72076 Tübingen</wicri:noRegion><wicri:noRegion>72076 Tübingen</wicri:noRegion><wicri:noRegion>72076 Tübingen</wicri:noRegion></affiliation></author><author><name sortKey="Schumacher, Karin" sort="Schumacher, Karin" uniqKey="Schumacher K" first="Karin" last="Schumacher">Karin Schumacher</name><affiliation wicri:level="3"><nlm:aff id="A2">Developmental Biology of Plants, Centre for Organismal Studies (COS), Heidelberg University, 69120 Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Developmental Biology of Plants, Centre for Organismal Studies (COS), Heidelberg University, 69120 Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Persson, Staffan" sort="Persson, Staffan" uniqKey="Persson S" first="Staffan" last="Persson">Staffan Persson</name><affiliation wicri:level="3"><nlm:aff id="A3">Max-Planck Institute for Molecular Plant Physiology, 14476 Potsdam, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Max-Planck Institute for Molecular Plant Physiology, 14476 Potsdam</wicri:regionArea><placeName><region type="land" nuts="2">Brandebourg</region><settlement type="city">Potsdam</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A9">Australian Research Council, Centre of Excellence in Plant Cell Walls, School of Botany, University of Melbourne, Parkville, Victoria 3010, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Australian Research Council, Centre of Excellence in Plant Cell Walls, School of Botany, University of Melbourne, Parkville, Victoria 3010</wicri:regionArea><orgName type="university">Université de Melbourne</orgName><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Russinova, Eugenia" sort="Russinova, Eugenia" uniqKey="Russinova E" first="Eugenia" last="Russinova">Eugenia Russinova</name><affiliation wicri:level="4"><nlm:aff id="A1">Department of Plant Systems Biology, VIB, 9052 Gent, Belgium; Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Gent, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Plant Systems Biology, VIB, 9052 Gent, Belgium; Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Gent</wicri:regionArea><orgName type="university">Université de Gand</orgName><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27250258</idno><idno type="pmc">4905525</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905525</idno><idno type="RBID">PMC:4905525</idno><idno type="doi">10.1038/nplants.2015.94</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">001E94</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001E94</idno><idno type="wicri:Area/Pmc/Curation">001D50</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001D50</idno><idno type="wicri:Area/Pmc/Checkpoint">000C49</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000C49</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">V-ATPase-activity in the TGN/EE is required for exocytosis and recycling in <italic>Arabidopsis</italic></title><author><name sortKey="Luo, Yu" sort="Luo, Yu" uniqKey="Luo Y" first="Yu" last="Luo">Yu Luo</name><affiliation wicri:level="4"><nlm:aff id="A1">Department of Plant Systems Biology, VIB, 9052 Gent, Belgium; Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Gent, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Plant Systems Biology, VIB, 9052 Gent, Belgium; Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Gent</wicri:regionArea><orgName type="university">Université de Gand</orgName><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Scholl, Stefan" sort="Scholl, Stefan" uniqKey="Scholl S" first="Stefan" last="Scholl">Stefan Scholl</name><affiliation wicri:level="3"><nlm:aff id="A2">Developmental Biology of Plants, Centre for Organismal Studies (COS), Heidelberg University, 69120 Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Developmental Biology of Plants, Centre for Organismal Studies (COS), Heidelberg University, 69120 Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Doering, Anett" sort="Doering, Anett" uniqKey="Doering A" first="Anett" last="Doering">Anett Doering</name><affiliation wicri:level="3"><nlm:aff id="A3">Max-Planck Institute for Molecular Plant Physiology, 14476 Potsdam, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Max-Planck Institute for Molecular Plant Physiology, 14476 Potsdam</wicri:regionArea><placeName><region type="land" nuts="2">Brandebourg</region><settlement type="city">Potsdam</settlement></placeName></affiliation></author><author><name sortKey="Zhang, Yi" sort="Zhang, Yi" uniqKey="Zhang Y" first="Yi" last="Zhang">Yi Zhang</name><affiliation wicri:level="3"><nlm:aff id="A3">Max-Planck Institute for Molecular Plant Physiology, 14476 Potsdam, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Max-Planck Institute for Molecular Plant Physiology, 14476 Potsdam</wicri:regionArea><placeName><region type="land" nuts="2">Brandebourg</region><settlement type="city">Potsdam</settlement></placeName></affiliation></author><author><name sortKey="Irani, Niloufer G" sort="Irani, Niloufer G" uniqKey="Irani N" first="Niloufer G." last="Irani">Niloufer G. Irani</name><affiliation wicri:level="4"><nlm:aff id="A1">Department of Plant Systems Biology, VIB, 9052 Gent, Belgium; Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Gent, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Plant Systems Biology, VIB, 9052 Gent, Belgium; Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Gent</wicri:regionArea><orgName type="university">Université de Gand</orgName><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Rubbo, Simone Di" sort="Rubbo, Simone Di" uniqKey="Rubbo S" first="Simone Di" last="Rubbo">Simone Di Rubbo</name><affiliation wicri:level="4"><nlm:aff id="A1">Department of Plant Systems Biology, VIB, 9052 Gent, Belgium; Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Gent, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Plant Systems Biology, VIB, 9052 Gent, Belgium; Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Gent</wicri:regionArea><orgName type="university">Université de Gand</orgName><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Neumetzler, Lutz" sort="Neumetzler, Lutz" uniqKey="Neumetzler L" first="Lutz" last="Neumetzler">Lutz Neumetzler</name><affiliation wicri:level="3"><nlm:aff id="A3">Max-Planck Institute for Molecular Plant Physiology, 14476 Potsdam, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Max-Planck Institute for Molecular Plant Physiology, 14476 Potsdam</wicri:regionArea><placeName><region type="land" nuts="2">Brandebourg</region><settlement type="city">Potsdam</settlement></placeName></affiliation></author><author><name sortKey="Krishnamoorthy, Praveen" sort="Krishnamoorthy, Praveen" uniqKey="Krishnamoorthy P" first="Praveen" last="Krishnamoorthy">Praveen Krishnamoorthy</name><affiliation wicri:level="3"><nlm:aff id="A3">Max-Planck Institute for Molecular Plant Physiology, 14476 Potsdam, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Max-Planck Institute for Molecular Plant Physiology, 14476 Potsdam</wicri:regionArea><placeName><region type="land" nuts="2">Brandebourg</region><settlement type="city">Potsdam</settlement></placeName></affiliation></author><author><name sortKey="Van Houtte, Isabelle" sort="Van Houtte, Isabelle" uniqKey="Van Houtte I" first="Isabelle" last="Van Houtte">Isabelle Van Houtte</name><affiliation wicri:level="4"><nlm:aff id="A1">Department of Plant Systems Biology, VIB, 9052 Gent, Belgium; Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Gent, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Plant Systems Biology, VIB, 9052 Gent, Belgium; Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Gent</wicri:regionArea><orgName type="university">Université de Gand</orgName><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Mylle, Evelien" sort="Mylle, Evelien" uniqKey="Mylle E" first="Evelien" last="Mylle">Evelien Mylle</name><affiliation wicri:level="4"><nlm:aff id="A1">Department of Plant Systems Biology, VIB, 9052 Gent, Belgium; Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Gent, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Plant Systems Biology, VIB, 9052 Gent, Belgium; Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Gent</wicri:regionArea><orgName type="university">Université de Gand</orgName><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Bischoff, Volker" sort="Bischoff, Volker" uniqKey="Bischoff V" first="Volker" last="Bischoff">Volker Bischoff</name><affiliation wicri:level="1"><nlm:aff id="A4">Institut National de la Recherche Agronomique, Unité Mixte de Recherche 1318, Institut Jean-Pierre Bourgin, Saclay Plant Sciences, 78000 Versailles, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Institut National de la Recherche Agronomique, Unité Mixte de Recherche 1318, Institut Jean-Pierre Bourgin, Saclay Plant Sciences, 78000 Versailles</wicri:regionArea><wicri:noRegion>78000 Versailles</wicri:noRegion><wicri:noRegion>78000 Versailles</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A5">AgroParisTech,Institut Jean-Pierre Bourgin, 78000 Versailles, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>AgroParisTech,Institut Jean-Pierre Bourgin, 78000 Versailles</wicri:regionArea><wicri:noRegion>78000 Versailles</wicri:noRegion><wicri:noRegion>78000 Versailles</wicri:noRegion></affiliation></author><author><name sortKey="Vernhettes, Samantha" sort="Vernhettes, Samantha" uniqKey="Vernhettes S" first="Samantha" last="Vernhettes">Samantha Vernhettes</name><affiliation wicri:level="1"><nlm:aff id="A4">Institut National de la Recherche Agronomique, Unité Mixte de Recherche 1318, Institut Jean-Pierre Bourgin, Saclay Plant Sciences, 78000 Versailles, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Institut National de la Recherche Agronomique, Unité Mixte de Recherche 1318, Institut Jean-Pierre Bourgin, Saclay Plant Sciences, 78000 Versailles</wicri:regionArea><wicri:noRegion>78000 Versailles</wicri:noRegion><wicri:noRegion>78000 Versailles</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A5">AgroParisTech,Institut Jean-Pierre Bourgin, 78000 Versailles, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>AgroParisTech,Institut Jean-Pierre Bourgin, 78000 Versailles</wicri:regionArea><wicri:noRegion>78000 Versailles</wicri:noRegion><wicri:noRegion>78000 Versailles</wicri:noRegion></affiliation></author><author><name sortKey="Winne, Johan" sort="Winne, Johan" uniqKey="Winne J" first="Johan" last="Winne">Johan Winne</name><affiliation wicri:level="4"><nlm:aff id="A6">Department of Organic Chemistry, Polymer Chemistry Research Group and Laboratory for Organic Synthesis, Ghent University, 9000 Gent, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Organic Chemistry, Polymer Chemistry Research Group and Laboratory for Organic Synthesis, Ghent University, 9000 Gent</wicri:regionArea><placeName><region type="province" nuts="2">Province de Flandre-Orientale</region><settlement type="city">Gand</settlement><settlement type="city">Gand</settlement></placeName><orgName type="university">Université de Gand</orgName></affiliation></author><author><name sortKey="Friml, Ji" sort="Friml, Ji" uniqKey="Friml J" first="Ji" last="Friml">Ji Friml</name><affiliation wicri:level="1"><nlm:aff id="A7">Institute of Science and Technology Austria (IST Austria), 3400 Klosterneuburg, Austria</nlm:aff><country xml:lang="fr">Autriche</country><wicri:regionArea>Institute of Science and Technology Austria (IST Austria), 3400 Klosterneuburg</wicri:regionArea><wicri:noRegion>3400 Klosterneuburg</wicri:noRegion></affiliation></author><author><name sortKey="Stierhof, York Dieter" sort="Stierhof, York Dieter" uniqKey="Stierhof Y" first="York-Dieter" last="Stierhof">York-Dieter Stierhof</name><affiliation wicri:level="1"><nlm:aff id="A8">Center for Plant Molecular Biology (ZMBP), University of Tübingen, 72076 Tübingen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Center for Plant Molecular Biology (ZMBP), University of Tübingen, 72076 Tübingen</wicri:regionArea><wicri:noRegion>72076 Tübingen</wicri:noRegion><wicri:noRegion>72076 Tübingen</wicri:noRegion><wicri:noRegion>72076 Tübingen</wicri:noRegion></affiliation></author><author><name sortKey="Schumacher, Karin" sort="Schumacher, Karin" uniqKey="Schumacher K" first="Karin" last="Schumacher">Karin Schumacher</name><affiliation wicri:level="3"><nlm:aff id="A2">Developmental Biology of Plants, Centre for Organismal Studies (COS), Heidelberg University, 69120 Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Developmental Biology of Plants, Centre for Organismal Studies (COS), Heidelberg University, 69120 Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Persson, Staffan" sort="Persson, Staffan" uniqKey="Persson S" first="Staffan" last="Persson">Staffan Persson</name><affiliation wicri:level="3"><nlm:aff id="A3">Max-Planck Institute for Molecular Plant Physiology, 14476 Potsdam, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Max-Planck Institute for Molecular Plant Physiology, 14476 Potsdam</wicri:regionArea><placeName><region type="land" nuts="2">Brandebourg</region><settlement type="city">Potsdam</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A9">Australian Research Council, Centre of Excellence in Plant Cell Walls, School of Botany, University of Melbourne, Parkville, Victoria 3010, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Australian Research Council, Centre of Excellence in Plant Cell Walls, School of Botany, University of Melbourne, Parkville, Victoria 3010</wicri:regionArea><orgName type="university">Université de Melbourne</orgName><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Russinova, Eugenia" sort="Russinova, Eugenia" uniqKey="Russinova E" first="Eugenia" last="Russinova">Eugenia Russinova</name><affiliation wicri:level="4"><nlm:aff id="A1">Department of Plant Systems Biology, VIB, 9052 Gent, Belgium; Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Gent, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Plant Systems Biology, VIB, 9052 Gent, Belgium; Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Gent</wicri:regionArea><orgName type="university">Université de Gand</orgName><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author></analytic><series><title level="j">Nature plants</title><idno type="eISSN">2055-0278</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P2">In plants, vacuolar H<sup>+</sup>-ATPase (V-ATPase) activity acidifies both the trans-Golgi network/early endosome (TGN/EE) and the vacuole. This dual V-ATPase function has impeded our understanding in how the pH homeostasis within the plant TGN/EE controls exo- and endocytosis. Here, we show that the weak V-ATPase mutant <italic>deetiolated3</italic> (<italic>det3</italic>) displayed a pH increase in the TGN/EE, but not in the vacuole, strongly impairing secretion and recycling of the brassinosteroid receptor and the cellulose synthase complexes to the plasma membrane, in contrast to mutants lacking tonoplast-localized V-ATPase activity only. The brassinosteroid insensitivity and the cellulose deficiency defects in <italic>det3</italic> were tightly correlated with reduced Golgi and TGN/EE motility. Thus, our results provide strong evidence that acidification of the TGN/EE, but not of the vacuole, is indispensable for functional secretion and recycling in plants.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">101651677</journal-id><journal-id journal-id-type="pubmed-jr-id">43556</journal-id><journal-id journal-id-type="nlm-ta">Nat Plants</journal-id><journal-id journal-id-type="iso-abbrev">Nat Plants</journal-id><journal-title-group><journal-title>Nature plants</journal-title></journal-title-group><issn pub-type="epub">2055-0278</issn></journal-meta><article-meta><article-id pub-id-type="pmid">27250258</article-id><article-id pub-id-type="pmc">4905525</article-id><article-id pub-id-type="doi">10.1038/nplants.2015.94</article-id><article-id pub-id-type="manuscript">EMS68478</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>V-ATPase-activity in the TGN/EE is required for exocytosis and recycling in <italic>Arabidopsis</italic></article-title></title-group><contrib-group><contrib contrib-type="author" equal-contrib="yes"><name><surname>Luo</surname><given-names>Yu</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author" equal-contrib="yes"><name><surname>Scholl</surname><given-names>Stefan</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author" equal-contrib="yes"><name><surname>Doering</surname><given-names>Anett</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Zhang</surname><given-names>Yi</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Irani</surname><given-names>Niloufer G.</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref ref-type="author-notes" rid="FN1">‡</xref></contrib><contrib contrib-type="author"><name><surname>Rubbo</surname><given-names>Simone Di</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Neumetzler</surname><given-names>Lutz</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Krishnamoorthy</surname><given-names>Praveen</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Van Houtte</surname><given-names>Isabelle</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Mylle</surname><given-names>Evelien</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Bischoff</surname><given-names>Volker</given-names></name><xref ref-type="aff" rid="A4">4</xref><xref ref-type="aff" rid="A5">5</xref></contrib><contrib contrib-type="author"><name><surname>Vernhettes</surname><given-names>Samantha</given-names></name><xref ref-type="aff" rid="A4">4</xref><xref ref-type="aff" rid="A5">5</xref></contrib><contrib contrib-type="author"><name><surname>Winne</surname><given-names>Johan</given-names></name><xref ref-type="aff" rid="A6">6</xref></contrib><contrib contrib-type="author"><name><surname>Friml</surname><given-names>Jiří</given-names></name><xref ref-type="aff" rid="A7">7</xref></contrib><contrib contrib-type="author"><name><surname>Stierhof</surname><given-names>York-Dieter</given-names></name><xref ref-type="aff" rid="A8">8</xref></contrib><contrib contrib-type="author" equal-contrib="yes"><name><surname>Schumacher</surname><given-names>Karin</given-names></name><xref ref-type="aff" rid="A2">2</xref><xref ref-type="corresp" rid="CR1">⋆</xref></contrib><contrib contrib-type="author" equal-contrib="yes"><name><surname>Persson</surname><given-names>Staffan</given-names></name><xref ref-type="aff" rid="A3">3</xref><xref ref-type="aff" rid="A9">9</xref><xref ref-type="corresp" rid="CR1">⋆</xref></contrib><contrib contrib-type="author" equal-contrib="yes"><name><surname>Russinova</surname><given-names>Eugenia</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref ref-type="corresp" rid="CR1">⋆</xref></contrib></contrib-group><aff id="A1"><label>1</label>Department of Plant Systems Biology, VIB, 9052 Gent, Belgium; Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Gent, Belgium</aff><aff id="A2"><label>2</label>Developmental Biology of Plants, Centre for Organismal Studies (COS), Heidelberg University, 69120 Heidelberg, Germany</aff><aff id="A3"><label>3</label>Max-Planck Institute for Molecular Plant Physiology, 14476 Potsdam, Germany</aff><aff id="A4"><label>4</label>Institut National de la Recherche Agronomique, Unité Mixte de Recherche 1318, Institut Jean-Pierre Bourgin, Saclay Plant Sciences, 78000 Versailles, France</aff><aff id="A5"><label>5</label>AgroParisTech,Institut Jean-Pierre Bourgin, 78000 Versailles, France</aff><aff id="A6"><label>6</label>Department of Organic Chemistry, Polymer Chemistry Research Group and Laboratory for Organic Synthesis, Ghent University, 9000 Gent, Belgium</aff><aff id="A7"><label>7</label>Institute of Science and Technology Austria (IST Austria), 3400 Klosterneuburg, Austria</aff><aff id="A8"><label>8</label>Center for Plant Molecular Biology (ZMBP), University of Tübingen, 72076 Tübingen, Germany</aff><aff id="A9"><label>9</label>Australian Research Council, Centre of Excellence in Plant Cell Walls, School of Botany, University of Melbourne, Parkville, Victoria 3010, Australia</aff><author-notes><corresp id="CR1"><label>⋆</label><email>Staffan.Persson@unimelb.au.edu</email>, <email>karin.schumacher@cos.uni-heidelberg.de</email>, and <email>eugenia.russinova@psb.vib-ugent.be</email></corresp><fn fn-type="present-address" id="FN1"><label>‡</label><p id="P1">Present address: Department of Plant Sciences, University of Oxford, Oxford OX1 3RB, UK.</p></fn></author-notes><pub-date pub-type="nihms-submitted"><day>8</day><month>6</month><year>2016</year></pub-date><pub-date pub-type="epub"><day>06</day><month>7</month><year>2015</year></pub-date><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="pmc-release"><day>13</day><month>6</month><year>2016</year></pub-date><volume>1</volume><fpage>15094</fpage><lpage>15094</lpage><pmc-comment>elocation-id from pubmed: 10.1038/nplants.2015.94</pmc-comment>
<abstract><p id="P2">In plants, vacuolar H<sup>+</sup>-ATPase (V-ATPase) activity acidifies both the trans-Golgi network/early endosome (TGN/EE) and the vacuole. This dual V-ATPase function has impeded our understanding in how the pH homeostasis within the plant TGN/EE controls exo- and endocytosis. Here, we show that the weak V-ATPase mutant <italic>deetiolated3</italic> (<italic>det3</italic>) displayed a pH increase in the TGN/EE, but not in the vacuole, strongly impairing secretion and recycling of the brassinosteroid receptor and the cellulose synthase complexes to the plasma membrane, in contrast to mutants lacking tonoplast-localized V-ATPase activity only. The brassinosteroid insensitivity and the cellulose deficiency defects in <italic>det3</italic> were tightly correlated with reduced Golgi and TGN/EE motility. Thus, our results provide strong evidence that acidification of the TGN/EE, but not of the vacuole, is indispensable for functional secretion and recycling in plants.</p></abstract></article-meta></front></pmc><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Autriche</li><li>Belgique</li><li>France</li></country><region><li>Bade-Wurtemberg</li><li>Brandebourg</li><li>District de Karlsruhe</li><li>Province de Flandre-Orientale</li><li>Région flamande</li><li>Victoria (État)</li></region><settlement><li>Gand</li><li>Heidelberg</li><li>Melbourne</li><li>Potsdam</li></settlement><orgName><li>Université de Gand</li><li>Université de Melbourne</li></orgName></list><tree><country name="Belgique"><region name="Région flamande"><name sortKey="Luo, Yu" sort="Luo, Yu" uniqKey="Luo Y" first="Yu" last="Luo">Yu Luo</name></region><name sortKey="Irani, Niloufer G" sort="Irani, Niloufer G" uniqKey="Irani N" first="Niloufer G." last="Irani">Niloufer G. Irani</name><name sortKey="Mylle, Evelien" sort="Mylle, Evelien" uniqKey="Mylle E" first="Evelien" last="Mylle">Evelien Mylle</name><name sortKey="Rubbo, Simone Di" sort="Rubbo, Simone Di" uniqKey="Rubbo S" first="Simone Di" last="Rubbo">Simone Di Rubbo</name><name sortKey="Russinova, Eugenia" sort="Russinova, Eugenia" uniqKey="Russinova E" first="Eugenia" last="Russinova">Eugenia Russinova</name><name sortKey="Van Houtte, Isabelle" sort="Van Houtte, Isabelle" uniqKey="Van Houtte I" first="Isabelle" last="Van Houtte">Isabelle Van Houtte</name><name sortKey="Winne, Johan" sort="Winne, Johan" uniqKey="Winne J" first="Johan" last="Winne">Johan Winne</name></country><country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Scholl, Stefan" sort="Scholl, Stefan" uniqKey="Scholl S" first="Stefan" last="Scholl">Stefan Scholl</name></region><name sortKey="Doering, Anett" sort="Doering, Anett" uniqKey="Doering A" first="Anett" last="Doering">Anett Doering</name><name sortKey="Krishnamoorthy, Praveen" sort="Krishnamoorthy, Praveen" uniqKey="Krishnamoorthy P" first="Praveen" last="Krishnamoorthy">Praveen Krishnamoorthy</name><name sortKey="Neumetzler, Lutz" sort="Neumetzler, Lutz" uniqKey="Neumetzler L" first="Lutz" last="Neumetzler">Lutz Neumetzler</name><name sortKey="Persson, Staffan" sort="Persson, Staffan" uniqKey="Persson S" first="Staffan" last="Persson">Staffan Persson</name><name sortKey="Schumacher, Karin" sort="Schumacher, Karin" uniqKey="Schumacher K" first="Karin" last="Schumacher">Karin Schumacher</name><name sortKey="Stierhof, York Dieter" sort="Stierhof, York Dieter" uniqKey="Stierhof Y" first="York-Dieter" last="Stierhof">York-Dieter Stierhof</name><name sortKey="Zhang, Yi" sort="Zhang, Yi" uniqKey="Zhang Y" first="Yi" last="Zhang">Yi Zhang</name></country><country name="France"><noRegion><name sortKey="Bischoff, Volker" sort="Bischoff, Volker" uniqKey="Bischoff V" first="Volker" last="Bischoff">Volker Bischoff</name></noRegion><name sortKey="Bischoff, Volker" sort="Bischoff, Volker" uniqKey="Bischoff V" first="Volker" last="Bischoff">Volker Bischoff</name><name sortKey="Vernhettes, Samantha" sort="Vernhettes, Samantha" uniqKey="Vernhettes S" first="Samantha" last="Vernhettes">Samantha Vernhettes</name><name sortKey="Vernhettes, Samantha" sort="Vernhettes, Samantha" uniqKey="Vernhettes S" first="Samantha" last="Vernhettes">Samantha Vernhettes</name></country><country name="Autriche"><noRegion><name sortKey="Friml, Ji" sort="Friml, Ji" uniqKey="Friml J" first="Ji" last="Friml">Ji Friml</name></noRegion></country><country name="Australie"><region name="Victoria (État)"><name sortKey="Persson, Staffan" sort="Persson, Staffan" uniqKey="Persson S" first="Staffan" last="Persson">Staffan Persson</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Pmc/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000C49 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Checkpoint/biblio.hfd -nk 000C49 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Asie
|area= AustralieFrV1
|flux= Pmc
|étape= Checkpoint
|type= RBID
|clé= PMC:4905525
|texte= V-ATPase-activity in the TGN/EE is required for exocytosis and recycling in Arabidopsis
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Checkpoint/RBID.i -Sk "pubmed:27250258" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a AustralieFrV1
| This area was generated with Dilib version V0.6.33. |  |