AustralieFrV1, PascalFrancis, Curation, bibRecord, 005990

International Myeloma Working Group Consensus Statement for the Management, Treatment, and Supportive Care of Patients With Myeloma Not Eligible for Standard Autologous Stem-Cell Transplantation

Identifieur interne : 005990 ( PascalFrancis/Curation ); précédent : 005989; suivant : 005991

International Myeloma Working Group Consensus Statement for the Management, Treatment, and Supportive Care of Patients With Myeloma Not Eligible for Standard Autologous Stem-Cell Transplantation

Auteurs : Antonio Palumbo [Italie] ; S. Vincent Rajkumar [États-Unis] ; Jesus F. San Miguel [Espagne] ; Alessandra Larocca [Italie] ; Ruben Niesvizky [États-Unis] ; Gareth Morgan [Royaume-Uni] ; Ola Landgren [États-Unis] ; Roman Hajek [République tchèque] ; Hermann Einsele [Allemagne] ; Kenneth C. Anderson [États-Unis] ; Meletios A. Dimopoulos [Grèce] ; Paul G. Richardson [États-Unis] ; Michele Cavo [Italie] ; Andrew Spencer [Australie] ; A. Keith Stewart [États-Unis] ; Kazuyuki Shimizu [Japon] ; Sagar Lonial [États-Unis] ; Pieter Sonneveld [Pays-Bas] ; Brian G. M. Durie [États-Unis] ; Philippe Moreau [France] ; Robert Z. Orlowski [États-Unis]

Source :

Journal of clinical oncology [ 0732-183X ] ; 2014.

RBID : Pascal:14-0114004

Descripteurs français

Pascal (Inist)
- Myélome, International, Consensus, Conduite à tenir, Traitement, Soin de support, Homme, Norme, Cellule hématopoïétique, Cellule souche, Cancérologie, Hémopathie maligne lymphoïde, Hémopathie lymphoïde B, Autogreffe de cellules souches hématopoïétiques.
Wicri :
- topic : Homme, Norme, Cellule souche.

English descriptors

KwdEn :
- Autologous hematopoietic stem cell transplantation, B cell neoplasm, Cancerology, Clinical management, Consensus, Hematopoietic cell, Human, International, Lymphoid neoplasm, Myeloma, Standards, Stem cell, Supportive care, Treatment.

Abstract

Purpose To provide an update on recent advances in the management of patients with multiple myeloma who are not eligible for autologous stem-cell transplantation. Methods A comprehensive review of the literature on diagnostic criteria is provided, and treatment options and management of adverse events are summarized. Results Patients with symptomatic disease and organ damage (ie, hypercalcemia, renal failure, anemia, or bone lesions) require immediate treatment. The International Staging System and chromosomal abnormalities identify high- and standard-risk patients. Proteasome inhibitors, immunomodulatory drugs, corticosteroids, and alkylating agents are the most active agents. The presence of concomitant diseases, frailty, or disability should be assessed and, if present, treated with reduced-dose approaches. Bone disease, renal damage, hematologic toxicities, infections, thromboembolism, and peripheral neuropathy are the most frequent disabling events requiring prompt and active supportive care. Conclusion These recommendations will help clinicians ensure the most appropriate care for patients with myeloma in everyday clinical practice.

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C01	`01`		`ENG`	@0 Purpose To provide an update on recent advances in the management of patients with multiple myeloma who are not eligible for autologous stem-cell transplantation. Methods A comprehensive review of the literature on diagnostic criteria is provided, and treatment options and management of adverse events are summarized. Results Patients with symptomatic disease and organ damage (ie, hypercalcemia, renal failure, anemia, or bone lesions) require immediate treatment. The International Staging System and chromosomal abnormalities identify high- and standard-risk patients. Proteasome inhibitors, immunomodulatory drugs, corticosteroids, and alkylating agents are the most active agents. The presence of concomitant diseases, frailty, or disability should be assessed and, if present, treated with reduced-dose approaches. Bone disease, renal damage, hematologic toxicities, infections, thromboembolism, and peripheral neuropathy are the most frequent disabling events requiring prompt and active supportive care. Conclusion These recommendations will help clinicians ensure the most appropriate care for patients with myeloma in everyday clinical practice.
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Le document en format XML

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<author><name sortKey="Anderson, Kenneth C" sort="Anderson, Kenneth C" uniqKey="Anderson K" first="Kenneth C." last="Anderson">Kenneth C. Anderson</name>
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<author><name sortKey="Dimopoulos, Meletios A" sort="Dimopoulos, Meletios A" uniqKey="Dimopoulos M" first="Meletios A." last="Dimopoulos">Meletios A. Dimopoulos</name>
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<author><name sortKey="Spencer, Andrew" sort="Spencer, Andrew" uniqKey="Spencer A" first="Andrew" last="Spencer">Andrew Spencer</name>
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<author><name sortKey="Keith Stewart, A" sort="Keith Stewart, A" uniqKey="Keith Stewart A" first="A." last="Keith Stewart">A. Keith Stewart</name>
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<author><name sortKey="Lonial, Sagar" sort="Lonial, Sagar" uniqKey="Lonial S" first="Sagar" last="Lonial">Sagar Lonial</name>
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<author><name sortKey="Sonneveld, Pieter" sort="Sonneveld, Pieter" uniqKey="Sonneveld P" first="Pieter" last="Sonneveld">Pieter Sonneveld</name>
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<author><name sortKey="Durie, Brian G M" sort="Durie, Brian G M" uniqKey="Durie B" first="Brian G. M." last="Durie">Brian G. M. Durie</name>
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<author><name sortKey="Moreau, Philippe" sort="Moreau, Philippe" uniqKey="Moreau P" first="Philippe" last="Moreau">Philippe Moreau</name>
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<author><name sortKey="Orlowski, Robert Z" sort="Orlowski, Robert Z" uniqKey="Orlowski R" first="Robert Z." last="Orlowski">Robert Z. Orlowski</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">International Myeloma Working Group Consensus Statement for the Management, Treatment, and Supportive Care of Patients With Myeloma Not Eligible for Standard Autologous Stem-Cell Transplantation</title>
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<author><name sortKey="Vincent Rajkumar, S" sort="Vincent Rajkumar, S" uniqKey="Vincent Rajkumar S" first="S." last="Vincent Rajkumar">S. Vincent Rajkumar</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Mayo Clinic</s1>
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<s3>USA</s3>
<sZ>2 aut.</sZ>
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<author><name sortKey="San Miguel, Jesus F" sort="San Miguel, Jesus F" uniqKey="San Miguel J" first="Jesus F." last="San Miguel">Jesus F. San Miguel</name>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>University Hospital of Salamanca</s1>
<s2>Salamanca</s2>
<s3>ESP</s3>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>Espagne</country>
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<author><name sortKey="Larocca, Alessandra" sort="Larocca, Alessandra" uniqKey="Larocca A" first="Alessandra" last="Larocca">Alessandra Larocca</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>University of Torino</s1>
<s2>Torino</s2>
<s3>ITA</s3>
<sZ>1 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Italie</country>
</affiliation>
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<author><name sortKey="Niesvizky, Ruben" sort="Niesvizky, Ruben" uniqKey="Niesvizky R" first="Ruben" last="Niesvizky">Ruben Niesvizky</name>
<affiliation wicri:level="1"><inist:fA14 i1="05"><s1>Weill Cornell Medical College</s1>
<s2>New York, NY</s2>
<s3>USA</s3>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
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<affiliation wicri:level="1"><inist:fA14 i1="06"><s1>Royal Marsden Hospital</s1>
<s2>London</s2>
<s3>GBR</s3>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
</affiliation>
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<author><name sortKey="Landgren, Ola" sort="Landgren, Ola" uniqKey="Landgren O" first="Ola" last="Landgren">Ola Landgren</name>
<affiliation wicri:level="1"><inist:fA14 i1="07"><s1>National Cancer Institute</s1>
<s2>Bethesda, MD</s2>
<s3>USA</s3>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Hajek, Roman" sort="Hajek, Roman" uniqKey="Hajek R" first="Roman" last="Hajek">Roman Hajek</name>
<affiliation wicri:level="1"><inist:fA14 i1="08"><s1>University of Ostrava School of Medicine and University Hospital Ostrava</s1>
<s2>Ostrava</s2>
<s3>CZE</s3>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>République tchèque</country>
</affiliation>
</author>
<author><name sortKey="Einsele, Hermann" sort="Einsele, Hermann" uniqKey="Einsele H" first="Hermann" last="Einsele">Hermann Einsele</name>
<affiliation wicri:level="1"><inist:fA14 i1="09"><s1>University of Wurzburg</s1>
<s2>Wurzburg</s2>
<s3>DEU</s3>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
</affiliation>
</author>
<author><name sortKey="Anderson, Kenneth C" sort="Anderson, Kenneth C" uniqKey="Anderson K" first="Kenneth C." last="Anderson">Kenneth C. Anderson</name>
<affiliation wicri:level="1"><inist:fA14 i1="10"><s1>Dana-Farber Cancer Institute</s1>
<s2>Boston, MA</s2>
<s3>USA</s3>
<sZ>10 aut.</sZ>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Dimopoulos, Meletios A" sort="Dimopoulos, Meletios A" uniqKey="Dimopoulos M" first="Meletios A." last="Dimopoulos">Meletios A. Dimopoulos</name>
<affiliation wicri:level="1"><inist:fA14 i1="11"><s1>University of Athens School of Medicine</s1>
<s2>Athens</s2>
<s3>GRC</s3>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>Grèce</country>
</affiliation>
</author>
<author><name sortKey="Richardson, Paul G" sort="Richardson, Paul G" uniqKey="Richardson P" first="Paul G." last="Richardson">Paul G. Richardson</name>
<affiliation wicri:level="1"><inist:fA14 i1="10"><s1>Dana-Farber Cancer Institute</s1>
<s2>Boston, MA</s2>
<s3>USA</s3>
<sZ>10 aut.</sZ>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Cavo, Michele" sort="Cavo, Michele" uniqKey="Cavo M" first="Michele" last="Cavo">Michele Cavo</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Seragnoli Institute of Hematology, Bologna University School of Medicine</s1>
<s2>Bologna</s2>
<s3>ITA</s3>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>Italie</country>
</affiliation>
</author>
<author><name sortKey="Spencer, Andrew" sort="Spencer, Andrew" uniqKey="Spencer A" first="Andrew" last="Spencer">Andrew Spencer</name>
<affiliation wicri:level="1"><inist:fA14 i1="12"><s1>Alfred Hospital</s1>
<s2>Melbourne, Victoria</s2>
<s3>AUS</s3>
<sZ>14 aut.</sZ>
</inist:fA14>
<country>Australie</country>
</affiliation>
</author>
<author><name sortKey="Keith Stewart, A" sort="Keith Stewart, A" uniqKey="Keith Stewart A" first="A." last="Keith Stewart">A. Keith Stewart</name>
<affiliation wicri:level="1"><inist:fA14 i1="13"><s1>Mayo Clinic</s1>
<s2>Scottsdale, AZ</s2>
<s3>USA</s3>
<sZ>15 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Shimizu, Kazuyuki" sort="Shimizu, Kazuyuki" uniqKey="Shimizu K" first="Kazuyuki" last="Shimizu">Kazuyuki Shimizu</name>
<affiliation wicri:level="1"><inist:fA14 i1="14"><s1>Aichi Gakuin Hospital</s1>
<s2>Nagoya</s2>
<s3>JPN</s3>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>Japon</country>
</affiliation>
</author>
<author><name sortKey="Lonial, Sagar" sort="Lonial, Sagar" uniqKey="Lonial S" first="Sagar" last="Lonial">Sagar Lonial</name>
<affiliation wicri:level="1"><inist:fA14 i1="15"><s1>Emory University</s1>
<s2>Atlanta, GA</s2>
<s3>USA</s3>
<sZ>17 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Sonneveld, Pieter" sort="Sonneveld, Pieter" uniqKey="Sonneveld P" first="Pieter" last="Sonneveld">Pieter Sonneveld</name>
<affiliation wicri:level="1"><inist:fA14 i1="16"><s1>Erasmus Medical Centre</s1>
<s2>Rotterdam</s2>
<s3>NLD</s3>
<sZ>18 aut.</sZ>
</inist:fA14>
<country>Pays-Bas</country>
</affiliation>
</author>
<author><name sortKey="Durie, Brian G M" sort="Durie, Brian G M" uniqKey="Durie B" first="Brian G. M." last="Durie">Brian G. M. Durie</name>
<affiliation wicri:level="1"><inist:fA14 i1="17"><s1>Cedars-Sinai Comprehensive Cancer Center</s1>
<s2>Los Angeles, CA</s2>
<s3>USA</s3>
<sZ>19 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Moreau, Philippe" sort="Moreau, Philippe" uniqKey="Moreau P" first="Philippe" last="Moreau">Philippe Moreau</name>
<affiliation wicri:level="1"><inist:fA14 i1="18"><s1>University Hospital</s1>
<s2>Nantes</s2>
<s3>FRA</s3>
<sZ>20 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Orlowski, Robert Z" sort="Orlowski, Robert Z" uniqKey="Orlowski R" first="Robert Z." last="Orlowski">Robert Z. Orlowski</name>
<affiliation wicri:level="1"><inist:fA14 i1="19"><s1>MD Anderson Cancer Center</s1>
<s2>Houston, TX</s2>
<s3>USA</s3>
<sZ>21 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Journal of clinical oncology</title>
<title level="j" type="abbreviated">J. clin. oncol.</title>
<idno type="ISSN">0732-183X</idno>
<imprint><date when="2014">2014</date>
</imprint>
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<seriesStmt><title level="j" type="main">Journal of clinical oncology</title>
<title level="j" type="abbreviated">J. clin. oncol.</title>
<idno type="ISSN">0732-183X</idno>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Autologous hematopoietic stem cell transplantation</term>
<term>B cell neoplasm</term>
<term>Cancerology</term>
<term>Clinical management</term>
<term>Consensus</term>
<term>Hematopoietic cell</term>
<term>Human</term>
<term>International</term>
<term>Lymphoid neoplasm</term>
<term>Myeloma</term>
<term>Standards</term>
<term>Stem cell</term>
<term>Supportive care</term>
<term>Treatment</term>
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<keywords scheme="Pascal" xml:lang="fr"><term>Myélome</term>
<term>International</term>
<term>Consensus</term>
<term>Conduite à tenir</term>
<term>Traitement</term>
<term>Soin de support</term>
<term>Homme</term>
<term>Norme</term>
<term>Cellule hématopoïétique</term>
<term>Cellule souche</term>
<term>Cancérologie</term>
<term>Hémopathie maligne lymphoïde</term>
<term>Hémopathie lymphoïde B</term>
<term>Autogreffe de cellules souches hématopoïétiques</term>
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<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term>
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<front><div type="abstract" xml:lang="en">Purpose To provide an update on recent advances in the management of patients with multiple myeloma who are not eligible for autologous stem-cell transplantation. Methods A comprehensive review of the literature on diagnostic criteria is provided, and treatment options and management of adverse events are summarized. Results Patients with symptomatic disease and organ damage (ie, hypercalcemia, renal failure, anemia, or bone lesions) require immediate treatment. The International Staging System and chromosomal abnormalities identify high- and standard-risk patients. Proteasome inhibitors, immunomodulatory drugs, corticosteroids, and alkylating agents are the most active agents. The presence of concomitant diseases, frailty, or disability should be assessed and, if present, treated with reduced-dose approaches. Bone disease, renal damage, hematologic toxicities, infections, thromboembolism, and peripheral neuropathy are the most frequent disabling events requiring prompt and active supportive care. Conclusion These recommendations will help clinicians ensure the most appropriate care for patients with myeloma in everyday clinical practice.</div>
</front>
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<fA08 i1="01" i2="1" l="ENG"><s1>International Myeloma Working Group Consensus Statement for the Management, Treatment, and Supportive Care of Patients With Myeloma Not Eligible for Standard Autologous Stem-Cell Transplantation</s1>
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<fA11 i1="01" i2="1"><s1>PALUMBO (Antonio)</s1>
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<fA11 i1="10" i2="1"><s1>ANDERSON (Kenneth C.)</s1>
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<fA11 i1="15" i2="1"><s1>KEITH STEWART (A.)</s1>
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<fA11 i1="17" i2="1"><s1>LONIAL (Sagar)</s1>
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<fA11 i1="18" i2="1"><s1>SONNEVELD (Pieter)</s1>
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<fA11 i1="20" i2="1"><s1>MOREAU (Philippe)</s1>
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<fA11 i1="21" i2="1"><s1>ORLOWSKI (Robert Z.)</s1>
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<sZ>1 aut.</sZ>
<sZ>4 aut.</sZ>
</fA14>
<fA14 i1="02"><s1>Seragnoli Institute of Hematology, Bologna University School of Medicine</s1>
<s2>Bologna</s2>
<s3>ITA</s3>
<sZ>13 aut.</sZ>
</fA14>
<fA14 i1="03"><s1>Mayo Clinic</s1>
<s2>Rochester, MN</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
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<fA14 i1="04"><s1>University Hospital of Salamanca</s1>
<s2>Salamanca</s2>
<s3>ESP</s3>
<sZ>3 aut.</sZ>
</fA14>
<fA14 i1="05"><s1>Weill Cornell Medical College</s1>
<s2>New York, NY</s2>
<s3>USA</s3>
<sZ>5 aut.</sZ>
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<fA14 i1="06"><s1>Royal Marsden Hospital</s1>
<s2>London</s2>
<s3>GBR</s3>
<sZ>6 aut.</sZ>
</fA14>
<fA14 i1="07"><s1>National Cancer Institute</s1>
<s2>Bethesda, MD</s2>
<s3>USA</s3>
<sZ>7 aut.</sZ>
</fA14>
<fA14 i1="08"><s1>University of Ostrava School of Medicine and University Hospital Ostrava</s1>
<s2>Ostrava</s2>
<s3>CZE</s3>
<sZ>8 aut.</sZ>
</fA14>
<fA14 i1="09"><s1>University of Wurzburg</s1>
<s2>Wurzburg</s2>
<s3>DEU</s3>
<sZ>9 aut.</sZ>
</fA14>
<fA14 i1="10"><s1>Dana-Farber Cancer Institute</s1>
<s2>Boston, MA</s2>
<s3>USA</s3>
<sZ>10 aut.</sZ>
<sZ>12 aut.</sZ>
</fA14>
<fA14 i1="11"><s1>University of Athens School of Medicine</s1>
<s2>Athens</s2>
<s3>GRC</s3>
<sZ>11 aut.</sZ>
</fA14>
<fA14 i1="12"><s1>Alfred Hospital</s1>
<s2>Melbourne, Victoria</s2>
<s3>AUS</s3>
<sZ>14 aut.</sZ>
</fA14>
<fA14 i1="13"><s1>Mayo Clinic</s1>
<s2>Scottsdale, AZ</s2>
<s3>USA</s3>
<sZ>15 aut.</sZ>
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<fA14 i1="14"><s1>Aichi Gakuin Hospital</s1>
<s2>Nagoya</s2>
<s3>JPN</s3>
<sZ>16 aut.</sZ>
</fA14>
<fA14 i1="15"><s1>Emory University</s1>
<s2>Atlanta, GA</s2>
<s3>USA</s3>
<sZ>17 aut.</sZ>
</fA14>
<fA14 i1="16"><s1>Erasmus Medical Centre</s1>
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<s3>NLD</s3>
<sZ>18 aut.</sZ>
</fA14>
<fA14 i1="17"><s1>Cedars-Sinai Comprehensive Cancer Center</s1>
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<sZ>19 aut.</sZ>
</fA14>
<fA14 i1="18"><s1>University Hospital</s1>
<s2>Nantes</s2>
<s3>FRA</s3>
<sZ>20 aut.</sZ>
</fA14>
<fA14 i1="19"><s1>MD Anderson Cancer Center</s1>
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<sZ>21 aut.</sZ>
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<fA60><s1>P</s1>
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<fA61><s0>A</s0>
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<fA64 i1="01" i2="1"><s0>Journal of clinical oncology</s0>
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<fC01 i1="01" l="ENG"><s0>Purpose To provide an update on recent advances in the management of patients with multiple myeloma who are not eligible for autologous stem-cell transplantation. Methods A comprehensive review of the literature on diagnostic criteria is provided, and treatment options and management of adverse events are summarized. Results Patients with symptomatic disease and organ damage (ie, hypercalcemia, renal failure, anemia, or bone lesions) require immediate treatment. The International Staging System and chromosomal abnormalities identify high- and standard-risk patients. Proteasome inhibitors, immunomodulatory drugs, corticosteroids, and alkylating agents are the most active agents. The presence of concomitant diseases, frailty, or disability should be assessed and, if present, treated with reduced-dose approaches. Bone disease, renal damage, hematologic toxicities, infections, thromboembolism, and peripheral neuropathy are the most frequent disabling events requiring prompt and active supportive care. Conclusion These recommendations will help clinicians ensure the most appropriate care for patients with myeloma in everyday clinical practice.</s0>
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<s5>09</s5>
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<fC03 i1="08" i2="X" l="SPA"><s0>Norma</s0>
<s5>09</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE"><s0>Cellule hématopoïétique</s0>
<s5>11</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG"><s0>Hematopoietic cell</s0>
<s5>11</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA"><s0>Célula hematopoyética</s0>
<s5>11</s5>
</fC03>
<fC03 i1="10" i2="X" l="FRE"><s0>Cellule souche</s0>
<s5>12</s5>
</fC03>
<fC03 i1="10" i2="X" l="ENG"><s0>Stem cell</s0>
<s5>12</s5>
</fC03>
<fC03 i1="10" i2="X" l="SPA"><s0>Célula primitiva</s0>
<s5>12</s5>
</fC03>
<fC03 i1="11" i2="X" l="FRE"><s0>Cancérologie</s0>
<s5>17</s5>
</fC03>
<fC03 i1="11" i2="X" l="ENG"><s0>Cancerology</s0>
<s5>17</s5>
</fC03>
<fC03 i1="11" i2="X" l="SPA"><s0>Cancerología</s0>
<s5>17</s5>
</fC03>
<fC03 i1="12" i2="X" l="FRE"><s0>Hémopathie maligne lymphoïde</s0>
<s4>CD</s4>
<s5>96</s5>
</fC03>
<fC03 i1="12" i2="X" l="ENG"><s0>Lymphoid neoplasm</s0>
<s4>CD</s4>
<s5>96</s5>
</fC03>
<fC03 i1="13" i2="X" l="FRE"><s0>Hémopathie lymphoïde B</s0>
<s4>CD</s4>
<s5>97</s5>
</fC03>
<fC03 i1="13" i2="X" l="ENG"><s0>B cell neoplasm</s0>
<s4>CD</s4>
<s5>97</s5>
</fC03>
<fC03 i1="14" i2="X" l="FRE"><s0>Autogreffe de cellules souches hématopoïétiques</s0>
<s4>CD</s4>
<s5>98</s5>
</fC03>
<fC03 i1="14" i2="X" l="ENG"><s0>Autologous hematopoietic stem cell transplantation</s0>
<s4>CD</s4>
<s5>98</s5>
</fC03>
<fC03 i1="14" i2="X" l="SPA"><s0>Autoinjerto de células precursoras hematopoyéticas</s0>
<s4>CD</s4>
<s5>98</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Hémopathie maligne</s0>
<s2>NM</s2>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Malignant hemopathy</s0>
<s2>NM</s2>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Hemopatía maligna</s0>
<s2>NM</s2>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Cancer</s0>
<s2>NM</s2>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Cancer</s0>
<s2>NM</s2>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Cáncer</s0>
<s2>NM</s2>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Immunoglobulinopathie</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Immunoglobulinopathy</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Inmunoglobulinopatía</s0>
<s5>38</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Syndrome lymphoprolifératif</s0>
<s2>NM</s2>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Lymphoproliferative syndrome</s0>
<s2>NM</s2>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Linfoproliferativo síndrome</s0>
<s2>NM</s2>
<s5>39</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Immunopathologie</s0>
<s5>40</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Immunopathology</s0>
<s5>40</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Inmunopatología</s0>
<s5>40</s5>
</fC07>
<fN21><s1>146</s1>
</fN21>
<fN44 i1="01"><s1>OTO</s1>
</fN44>
<fN82><s1>OTO</s1>
</fN82>
</pA>
</standard>
</inist>
</record>

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   |area=    AustralieFrV1
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   |texte=   International Myeloma Working Group Consensus Statement for the Management, Treatment, and Supportive Care of Patients With Myeloma Not Eligible for Standard Autologous Stem-Cell Transplantation
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International Myeloma Working Group Consensus Statement for the Management, Treatment, and Supportive Care of Patients With Myeloma Not Eligible for Standard Autologous Stem-Cell Transplantation

International Myeloma Working Group Consensus Statement for the Management, Treatment, and Supportive Care of Patients With Myeloma Not Eligible for Standard Autologous Stem-Cell Transplantation

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