AustralieFrV1, PascalFrancis, Corpus, bibRecord, 003B52

OMERACT/OARSI initiative to define states of severity and indication for joint replacement in hip and knee osteoarthritis

Identifieur interne : 003B52 ( PascalFrancis/Corpus ); précédent : 003B51; suivant : 003B53

OMERACT/OARSI initiative to define states of severity and indication for joint replacement in hip and knee osteoarthritis

Auteurs : Laure Gossec ; Gillian Hawker ; Aileen M. Davis ; Jean Francis Maillefert ; L. Stefan Lohmander ; Roy Altman ; Jolanda Cibere ; Philip G. Conaghan ; Marc C. Hochberg ; Joanne M. Jordan ; Jeffrey N. Katz ; Lyn March ; Nizar Mahomed ; Karel Pavelka ; Ewa M. Roos ; Maria E. Suarez-Almazor ; Gustavo Zanoli ; Maxime Dougados

Source :

Journal of rheumatology [ 0315-162X ] ; 2007.

RBID : Pascal:07-0314512

Descripteurs français

Pascal (Inist)
- Indication, Articulation coxofémorale, Hanche, Genou, Arthrose, Douleur, Pronostic, Ontario, Chirurgie orthopédique, Traitement, Coxarthrose, Prothèse de hanche, Gonarthrose, Interligne articulaire.

English descriptors

KwdEn :
- Hip, Hip joint, Hip prosthesis, Indication, Joint space, Knee, Knee osteoarthritis, Ontario, Orthopedic surgery, Osteoarthritis, Pain, Prognosis, Treatment.

Abstract

Objective. Time to theoretical indication of joint replacement surgery has been proposed as a primary outcome for potential structure-modifying interventions for osteoarthritis (OA). The objectives of this OMERACT/OARSI Working Group were to identify pain, physical function, and structure states that represent the progression from early to late disease for individuals with OA of the hip and knee, and to create a composite measure of these 3 domains to define states of OA severity and a surrogate measure of "need for joint replacement surgery." Methods. For pain, focus groups and one-on-one interviews were used. For function, Rasch analysis was performed on existing indices - the Hip Dysfunction and Osteoarthritis Outcome Score (HOOS) and the Knee injury and Osteoarthritis Outcome Score (KOOS), each of which subsumes the Western Ontario and McMaster University Osteoarthritis Index (WOMAC) questions. For structure, a comparison of existing indices (Kellgren-Lawrence, OARSI stages, and joint space width) was performed for the hip and the knee. Results. For pain, key features of pain that are most distressing to people with OA from early to late disease were identified. For function, the reduction of the number of items based on the existing indices continues. For structure, the analysis is also ongoing. Conclusion. Preliminary results were presented at OMERACT 8; the final objective will be to combine the 3 domains (pain, function, and structure) and to create a composite index that could define states of severity and "need for total joint replacement," which could be used to evaluate treatment response to disease-modifying drugs in OA clinical trials.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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C01	`01`		`ENG`	@0 Objective. Time to theoretical indication of joint replacement surgery has been proposed as a primary outcome for potential structure-modifying interventions for osteoarthritis (OA). The objectives of this OMERACT/OARSI Working Group were to identify pain, physical function, and structure states that represent the progression from early to late disease for individuals with OA of the hip and knee, and to create a composite measure of these 3 domains to define states of OA severity and a surrogate measure of "need for joint replacement surgery." Methods. For pain, focus groups and one-on-one interviews were used. For function, Rasch analysis was performed on existing indices - the Hip Dysfunction and Osteoarthritis Outcome Score (HOOS) and the Knee injury and Osteoarthritis Outcome Score (KOOS), each of which subsumes the Western Ontario and McMaster University Osteoarthritis Index (WOMAC) questions. For structure, a comparison of existing indices (Kellgren-Lawrence, OARSI stages, and joint space width) was performed for the hip and the knee. Results. For pain, key features of pain that are most distressing to people with OA from early to late disease were identified. For function, the reduction of the number of items based on the existing indices continues. For structure, the analysis is also ongoing. Conclusion. Preliminary results were presented at OMERACT 8; the final objective will be to combine the 3 domains (pain, function, and structure) and to create a composite index that could define states of severity and "need for total joint replacement," which could be used to evaluate treatment response to disease-modifying drugs in OA clinical trials.
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Format Inist (serveur)

NO :	PASCAL 07-0314512 INIST
ET :	OMERACT/OARSI initiative to define states of severity and indication for joint replacement in hip and knee osteoarthritis
AU :	GOSSEC (Laure); HAWKER (Gillian); DAVIS (Aileen M.); MAILLEFERT (Jean Francis); LOHMANDER (L. Stefan); ALTMAN (Roy); CIBERE (Jolanda); CONAGHAN (Philip G.); HOCHBERG (Marc C.); JORDAN (Joanne M.); KATZ (Jeffrey N.); MARCH (Lyn); MAHOMED (Nizar); PAVELKA (Karel); ROOS (Ewa M.); SUAREZ-ALMAZOR (Maria E.); ZANOLI (Gustavo); DOUGADOS (Maxime)
AF :	Medicine Faculty, Paris 5 René Descartes University/France (1 aut.); AP-HP, Cochin Hospital. Department of Rheumatology B/Paris/France (1 aut.); Division of Rheumatology, Department of Medicine, Women's College Hospital/France (2 aut.); Clinical Epidemiology and Health Care Research Program, Department of Health Policy, Management and Evaluation, Faculty of Medicine, University of Toronto/Toronto/Canada (2 aut., 3 aut.); Dijon University Hospital, and INSERM ERM 0207, University of Burgundy/Dijon/France (4 aut.); Outcomes and Population Health, Toronto Western Research Institute/Canada; Department of Orthopaedics, Clinical Sciences Lund, Lund University/Lund/Suède; Division of Rheumatology and Immunology, University of California at Los Angeles/Los Angeles, California/Etats-Unis; Division of Rheumatology, Department of Medicine, University of British Columbia, Arthritis Research Centre of Canada/Vancouver/Canada; Academic Unit of Musculoskeletal Disease, University of Leeds/Leeds/Royaume-Uni; Division of Rheumatology and Clinical Immunology, University of Maryland School of Medicine/Baltimore, Maryland/Etats-Unis; Departments of Medicine and Orthopaedics, Thurston Arthritis Research Center, University of North Carolina/Chapel Hill, North Carolina/Etats-Unis; Section of Clinical Sciences, Division of Rheumatology, Immunology and Allergy, and Department of Orthopaedic Surgery, Brigham and Women's Hospital/Boston, Massachusetts/Etats-Unis; University of Sydney, Florance and Cope Professorial Department of Rheumatology, Royal North Shore Hospital/St. Leonards, NSW/Australie; Musculoskeletal Health and Arthritis Program, University of Toronto, Toronto Western Hospital/Toronto/Canada; Institute of Rheumatology and Clinic of Rheumatology, Charles University/Prague/Tchèque, République; University of Texas, M.D. Anderson Cancer Center/Houston, Texas/Etats-Unis; Department of Orthopaedics, Ferrara University/Ferrara/Italie
DT :	Publication en série; Congrès; Niveau analytique
SO :	Journal of rheumatology; ISSN 0315-162X; Coden JRHUA9; Canada; Da. 2007; Vol. 34; No. 6; Pp. 1432-1435; Bibl. 12 ref.
LA :	Anglais
EA :	Objective. Time to theoretical indication of joint replacement surgery has been proposed as a primary outcome for potential structure-modifying interventions for osteoarthritis (OA). The objectives of this OMERACT/OARSI Working Group were to identify pain, physical function, and structure states that represent the progression from early to late disease for individuals with OA of the hip and knee, and to create a composite measure of these 3 domains to define states of OA severity and a surrogate measure of "need for joint replacement surgery." Methods. For pain, focus groups and one-on-one interviews were used. For function, Rasch analysis was performed on existing indices - the Hip Dysfunction and Osteoarthritis Outcome Score (HOOS) and the Knee injury and Osteoarthritis Outcome Score (KOOS), each of which subsumes the Western Ontario and McMaster University Osteoarthritis Index (WOMAC) questions. For structure, a comparison of existing indices (Kellgren-Lawrence, OARSI stages, and joint space width) was performed for the hip and the knee. Results. For pain, key features of pain that are most distressing to people with OA from early to late disease were identified. For function, the reduction of the number of items based on the existing indices continues. For structure, the analysis is also ongoing. Conclusion. Preliminary results were presented at OMERACT 8; the final objective will be to combine the 3 domains (pain, function, and structure) and to create a composite index that could define states of severity and "need for total joint replacement," which could be used to evaluate treatment response to disease-modifying drugs in OA clinical trials.
CC :	002B15E; 002B25I; 002B15I
FD :	Indication; Articulation coxofémorale; Hanche; Genou; Arthrose; Douleur; Pronostic; Ontario; Chirurgie orthopédique; Traitement; Coxarthrose; Prothèse de hanche; Gonarthrose; Interligne articulaire
FG :	Canada; Amérique du Nord; Amérique; Arthropathie; Maladie dégénérative; Système ostéoarticulaire pathologie
ED :	Indication; Hip joint; Hip; Knee; Osteoarthritis; Pain; Prognosis; Ontario; Orthopedic surgery; Treatment; Hip prosthesis; Knee osteoarthritis; Joint space
EG :	Canada; North America; America; Arthropathy; Degenerative disease; Diseases of the osteoarticular system
SD :	Indicación; Articulación coxofemoral; Cadera; Rodilla; Artrosis; Dolor; Pronóstico; Ontario; Cirugía ortopédica; Tratamiento; Prótesis de cadera
LO :	INIST-16024.354000149923590350
ID :	07-0314512

Links to Exploration step

Pascal:07-0314512

Le document en format XML

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<affiliation><inist:fA14 i1="11"><s1>Division of Rheumatology and Clinical Immunology, University of Maryland School of Medicine</s1>
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<author><name sortKey="Lohmander, L Stefan" sort="Lohmander, L Stefan" uniqKey="Lohmander L" first="L. Stefan" last="Lohmander">L. Stefan Lohmander</name>
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<author><name sortKey="Altman, Roy" sort="Altman, Roy" uniqKey="Altman R" first="Roy" last="Altman">Roy Altman</name>
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<author><name sortKey="Cibere, Jolanda" sort="Cibere, Jolanda" uniqKey="Cibere J" first="Jolanda" last="Cibere">Jolanda Cibere</name>
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<author><name sortKey="Conaghan, Philip G" sort="Conaghan, Philip G" uniqKey="Conaghan P" first="Philip G." last="Conaghan">Philip G. Conaghan</name>
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<author><name sortKey="Hochberg, Marc C" sort="Hochberg, Marc C" uniqKey="Hochberg M" first="Marc C." last="Hochberg">Marc C. Hochberg</name>
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<author><name sortKey="Jordan, Joanne M" sort="Jordan, Joanne M" uniqKey="Jordan J" first="Joanne M." last="Jordan">Joanne M. Jordan</name>
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<author><name sortKey="Katz, Jeffrey N" sort="Katz, Jeffrey N" uniqKey="Katz J" first="Jeffrey N." last="Katz">Jeffrey N. Katz</name>
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<author><name sortKey="March, Lyn" sort="March, Lyn" uniqKey="March L" first="Lyn" last="March">Lyn March</name>
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<author><name sortKey="Mahomed, Nizar" sort="Mahomed, Nizar" uniqKey="Mahomed N" first="Nizar" last="Mahomed">Nizar Mahomed</name>
</author>
<author><name sortKey="Pavelka, Karel" sort="Pavelka, Karel" uniqKey="Pavelka K" first="Karel" last="Pavelka">Karel Pavelka</name>
</author>
<author><name sortKey="Roos, Ewa M" sort="Roos, Ewa M" uniqKey="Roos E" first="Ewa M." last="Roos">Ewa M. Roos</name>
</author>
<author><name sortKey="Suarez Almazor, Maria E" sort="Suarez Almazor, Maria E" uniqKey="Suarez Almazor M" first="Maria E." last="Suarez-Almazor">Maria E. Suarez-Almazor</name>
</author>
<author><name sortKey="Zanoli, Gustavo" sort="Zanoli, Gustavo" uniqKey="Zanoli G" first="Gustavo" last="Zanoli">Gustavo Zanoli</name>
</author>
<author><name sortKey="Dougados, Maxime" sort="Dougados, Maxime" uniqKey="Dougados M" first="Maxime" last="Dougados">Maxime Dougados</name>
</author>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">OMERACT/OARSI initiative to define states of severity and indication for joint replacement in hip and knee osteoarthritis</title>
<author><name sortKey="Gossec, Laure" sort="Gossec, Laure" uniqKey="Gossec L" first="Laure" last="Gossec">Laure Gossec</name>
<affiliation><inist:fA14 i1="01"><s1>Medicine Faculty, Paris 5 René Descartes University</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
</inist:fA14>
</affiliation>
<affiliation><inist:fA14 i1="02"><s1>AP-HP, Cochin Hospital. Department of Rheumatology B</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
</inist:fA14>
</affiliation>
<affiliation><inist:fA14 i1="06"><s1>Outcomes and Population Health, Toronto Western Research Institute</s1>
<s3>CAN</s3>
</inist:fA14>
</affiliation>
<affiliation><inist:fA14 i1="07"><s1>Department of Orthopaedics, Clinical Sciences Lund, Lund University</s1>
<s2>Lund</s2>
<s3>SWE</s3>
</inist:fA14>
</affiliation>
<affiliation><inist:fA14 i1="08"><s1>Division of Rheumatology and Immunology, University of California at Los Angeles</s1>
<s2>Los Angeles, California</s2>
<s3>USA</s3>
</inist:fA14>
</affiliation>
<affiliation><inist:fA14 i1="09"><s1>Division of Rheumatology, Department of Medicine, University of British Columbia, Arthritis Research Centre of Canada</s1>
<s2>Vancouver</s2>
<s3>CAN</s3>
</inist:fA14>
</affiliation>
<affiliation><inist:fA14 i1="10"><s1>Academic Unit of Musculoskeletal Disease, University of Leeds</s1>
<s2>Leeds</s2>
<s3>GBR</s3>
</inist:fA14>
</affiliation>
<affiliation><inist:fA14 i1="11"><s1>Division of Rheumatology and Clinical Immunology, University of Maryland School of Medicine</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
</inist:fA14>
</affiliation>
<affiliation><inist:fA14 i1="12"><s1>Departments of Medicine and Orthopaedics, Thurston Arthritis Research Center, University of North Carolina</s1>
<s2>Chapel Hill, North Carolina</s2>
<s3>USA</s3>
</inist:fA14>
</affiliation>
<affiliation><inist:fA14 i1="13"><s1>Section of Clinical Sciences, Division of Rheumatology, Immunology and Allergy, and Department of Orthopaedic Surgery, Brigham and Women's Hospital</s1>
<s2>Boston, Massachusetts</s2>
<s3>USA</s3>
</inist:fA14>
</affiliation>
<affiliation><inist:fA14 i1="14"><s1>University of Sydney, Florance and Cope Professorial Department of Rheumatology, Royal North Shore Hospital</s1>
<s2>St. Leonards, NSW</s2>
<s3>AUS</s3>
</inist:fA14>
</affiliation>
<affiliation><inist:fA14 i1="15"><s1>Musculoskeletal Health and Arthritis Program, University of Toronto, Toronto Western Hospital</s1>
<s2>Toronto</s2>
<s3>CAN</s3>
</inist:fA14>
</affiliation>
<affiliation><inist:fA14 i1="16"><s1>Institute of Rheumatology and Clinic of Rheumatology, Charles University</s1>
<s2>Prague</s2>
<s3>CZE</s3>
</inist:fA14>
</affiliation>
<affiliation><inist:fA14 i1="17"><s1>University of Texas, M.D. Anderson Cancer Center</s1>
<s2>Houston, Texas</s2>
<s3>USA</s3>
</inist:fA14>
</affiliation>
<affiliation><inist:fA14 i1="18"><s1>Department of Orthopaedics, Ferrara University</s1>
<s2>Ferrara</s2>
<s3>ITA</s3>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Hawker, Gillian" sort="Hawker, Gillian" uniqKey="Hawker G" first="Gillian" last="Hawker">Gillian Hawker</name>
<affiliation><inist:fA14 i1="03"><s1>Division of Rheumatology, Department of Medicine, Women's College Hospital</s1>
<s3>FRA</s3>
<sZ>2 aut.</sZ>
</inist:fA14>
</affiliation>
<affiliation><inist:fA14 i1="04"><s1>Clinical Epidemiology and Health Care Research Program, Department of Health Policy, Management and Evaluation, Faculty of Medicine, University of Toronto</s1>
<s2>Toronto</s2>
<s3>CAN</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Davis, Aileen M" sort="Davis, Aileen M" uniqKey="Davis A" first="Aileen M." last="Davis">Aileen M. Davis</name>
<affiliation><inist:fA14 i1="04"><s1>Clinical Epidemiology and Health Care Research Program, Department of Health Policy, Management and Evaluation, Faculty of Medicine, University of Toronto</s1>
<s2>Toronto</s2>
<s3>CAN</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Maillefert, Jean Francis" sort="Maillefert, Jean Francis" uniqKey="Maillefert J" first="Jean Francis" last="Maillefert">Jean Francis Maillefert</name>
<affiliation><inist:fA14 i1="05"><s1>Dijon University Hospital, and INSERM ERM 0207, University of Burgundy</s1>
<s2>Dijon</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Lohmander, L Stefan" sort="Lohmander, L Stefan" uniqKey="Lohmander L" first="L. Stefan" last="Lohmander">L. Stefan Lohmander</name>
</author>
<author><name sortKey="Altman, Roy" sort="Altman, Roy" uniqKey="Altman R" first="Roy" last="Altman">Roy Altman</name>
</author>
<author><name sortKey="Cibere, Jolanda" sort="Cibere, Jolanda" uniqKey="Cibere J" first="Jolanda" last="Cibere">Jolanda Cibere</name>
</author>
<author><name sortKey="Conaghan, Philip G" sort="Conaghan, Philip G" uniqKey="Conaghan P" first="Philip G." last="Conaghan">Philip G. Conaghan</name>
</author>
<author><name sortKey="Hochberg, Marc C" sort="Hochberg, Marc C" uniqKey="Hochberg M" first="Marc C." last="Hochberg">Marc C. Hochberg</name>
</author>
<author><name sortKey="Jordan, Joanne M" sort="Jordan, Joanne M" uniqKey="Jordan J" first="Joanne M." last="Jordan">Joanne M. Jordan</name>
</author>
<author><name sortKey="Katz, Jeffrey N" sort="Katz, Jeffrey N" uniqKey="Katz J" first="Jeffrey N." last="Katz">Jeffrey N. Katz</name>
</author>
<author><name sortKey="March, Lyn" sort="March, Lyn" uniqKey="March L" first="Lyn" last="March">Lyn March</name>
</author>
<author><name sortKey="Mahomed, Nizar" sort="Mahomed, Nizar" uniqKey="Mahomed N" first="Nizar" last="Mahomed">Nizar Mahomed</name>
</author>
<author><name sortKey="Pavelka, Karel" sort="Pavelka, Karel" uniqKey="Pavelka K" first="Karel" last="Pavelka">Karel Pavelka</name>
</author>
<author><name sortKey="Roos, Ewa M" sort="Roos, Ewa M" uniqKey="Roos E" first="Ewa M." last="Roos">Ewa M. Roos</name>
</author>
<author><name sortKey="Suarez Almazor, Maria E" sort="Suarez Almazor, Maria E" uniqKey="Suarez Almazor M" first="Maria E." last="Suarez-Almazor">Maria E. Suarez-Almazor</name>
</author>
<author><name sortKey="Zanoli, Gustavo" sort="Zanoli, Gustavo" uniqKey="Zanoli G" first="Gustavo" last="Zanoli">Gustavo Zanoli</name>
</author>
<author><name sortKey="Dougados, Maxime" sort="Dougados, Maxime" uniqKey="Dougados M" first="Maxime" last="Dougados">Maxime Dougados</name>
</author>
</analytic>
<series><title level="j" type="main">Journal of rheumatology</title>
<title level="j" type="abbreviated">J. rheumatol.</title>
<idno type="ISSN">0315-162X</idno>
<imprint><date when="2007">2007</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Journal of rheumatology</title>
<title level="j" type="abbreviated">J. rheumatol.</title>
<idno type="ISSN">0315-162X</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Hip</term>
<term>Hip joint</term>
<term>Hip prosthesis</term>
<term>Indication</term>
<term>Joint space</term>
<term>Knee</term>
<term>Knee osteoarthritis</term>
<term>Ontario</term>
<term>Orthopedic surgery</term>
<term>Osteoarthritis</term>
<term>Pain</term>
<term>Prognosis</term>
<term>Treatment</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Indication</term>
<term>Articulation coxofémorale</term>
<term>Hanche</term>
<term>Genou</term>
<term>Arthrose</term>
<term>Douleur</term>
<term>Pronostic</term>
<term>Ontario</term>
<term>Chirurgie orthopédique</term>
<term>Traitement</term>
<term>Coxarthrose</term>
<term>Prothèse de hanche</term>
<term>Gonarthrose</term>
<term>Interligne articulaire</term>
</keywords>
</textClass>
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<front><div type="abstract" xml:lang="en">Objective. Time to theoretical indication of joint replacement surgery has been proposed as a primary outcome for potential structure-modifying interventions for osteoarthritis (OA). The objectives of this OMERACT/OARSI Working Group were to identify pain, physical function, and structure states that represent the progression from early to late disease for individuals with OA of the hip and knee, and to create a composite measure of these 3 domains to define states of OA severity and a surrogate measure of "need for joint replacement surgery." Methods. For pain, focus groups and one-on-one interviews were used. For function, Rasch analysis was performed on existing indices - the Hip Dysfunction and Osteoarthritis Outcome Score (HOOS) and the Knee injury and Osteoarthritis Outcome Score (KOOS), each of which subsumes the Western Ontario and McMaster University Osteoarthritis Index (WOMAC) questions. For structure, a comparison of existing indices (Kellgren-Lawrence, OARSI stages, and joint space width) was performed for the hip and the knee. Results. For pain, key features of pain that are most distressing to people with OA from early to late disease were identified. For function, the reduction of the number of items based on the existing indices continues. For structure, the analysis is also ongoing. Conclusion. Preliminary results were presented at OMERACT 8; the final objective will be to combine the 3 domains (pain, function, and structure) and to create a composite index that could define states of severity and "need for total joint replacement," which could be used to evaluate treatment response to disease-modifying drugs in OA clinical trials.</div>
</front>
</TEI>
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<fA08 i1="01" i2="1" l="ENG"><s1>OMERACT/OARSI initiative to define states of severity and indication for joint replacement in hip and knee osteoarthritis</s1>
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<fA11 i1="02" i2="1"><s1>HAWKER (Gillian)</s1>
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<fA11 i1="04" i2="1"><s1>MAILLEFERT (Jean Francis)</s1>
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<fA11 i1="05" i2="1"><s1>LOHMANDER (L. Stefan)</s1>
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<fA11 i1="06" i2="1"><s1>ALTMAN (Roy)</s1>
</fA11>
<fA11 i1="07" i2="1"><s1>CIBERE (Jolanda)</s1>
</fA11>
<fA11 i1="08" i2="1"><s1>CONAGHAN (Philip G.)</s1>
</fA11>
<fA11 i1="09" i2="1"><s1>HOCHBERG (Marc C.)</s1>
</fA11>
<fA11 i1="10" i2="1"><s1>JORDAN (Joanne M.)</s1>
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<fA11 i1="11" i2="1"><s1>KATZ (Jeffrey N.)</s1>
</fA11>
<fA11 i1="12" i2="1"><s1>MARCH (Lyn)</s1>
</fA11>
<fA11 i1="13" i2="1"><s1>MAHOMED (Nizar)</s1>
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<fA11 i1="14" i2="1"><s1>PAVELKA (Karel)</s1>
</fA11>
<fA11 i1="15" i2="1"><s1>ROOS (Ewa M.)</s1>
</fA11>
<fA11 i1="16" i2="1"><s1>SUAREZ-ALMAZOR (Maria E.)</s1>
</fA11>
<fA11 i1="17" i2="1"><s1>ZANOLI (Gustavo)</s1>
</fA11>
<fA11 i1="18" i2="1"><s1>DOUGADOS (Maxime)</s1>
</fA11>
<fA14 i1="01"><s1>Medicine Faculty, Paris 5 René Descartes University</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
</fA14>
<fA14 i1="02"><s1>AP-HP, Cochin Hospital. Department of Rheumatology B</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
</fA14>
<fA14 i1="03"><s1>Division of Rheumatology, Department of Medicine, Women's College Hospital</s1>
<s3>FRA</s3>
<sZ>2 aut.</sZ>
</fA14>
<fA14 i1="04"><s1>Clinical Epidemiology and Health Care Research Program, Department of Health Policy, Management and Evaluation, Faculty of Medicine, University of Toronto</s1>
<s2>Toronto</s2>
<s3>CAN</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
</fA14>
<fA14 i1="05"><s1>Dijon University Hospital, and INSERM ERM 0207, University of Burgundy</s1>
<s2>Dijon</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
</fA14>
<fA14 i1="06"><s1>Outcomes and Population Health, Toronto Western Research Institute</s1>
<s3>CAN</s3>
</fA14>
<fA14 i1="07"><s1>Department of Orthopaedics, Clinical Sciences Lund, Lund University</s1>
<s2>Lund</s2>
<s3>SWE</s3>
</fA14>
<fA14 i1="08"><s1>Division of Rheumatology and Immunology, University of California at Los Angeles</s1>
<s2>Los Angeles, California</s2>
<s3>USA</s3>
</fA14>
<fA14 i1="09"><s1>Division of Rheumatology, Department of Medicine, University of British Columbia, Arthritis Research Centre of Canada</s1>
<s2>Vancouver</s2>
<s3>CAN</s3>
</fA14>
<fA14 i1="10"><s1>Academic Unit of Musculoskeletal Disease, University of Leeds</s1>
<s2>Leeds</s2>
<s3>GBR</s3>
</fA14>
<fA14 i1="11"><s1>Division of Rheumatology and Clinical Immunology, University of Maryland School of Medicine</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
</fA14>
<fA14 i1="12"><s1>Departments of Medicine and Orthopaedics, Thurston Arthritis Research Center, University of North Carolina</s1>
<s2>Chapel Hill, North Carolina</s2>
<s3>USA</s3>
</fA14>
<fA14 i1="13"><s1>Section of Clinical Sciences, Division of Rheumatology, Immunology and Allergy, and Department of Orthopaedic Surgery, Brigham and Women's Hospital</s1>
<s2>Boston, Massachusetts</s2>
<s3>USA</s3>
</fA14>
<fA14 i1="14"><s1>University of Sydney, Florance and Cope Professorial Department of Rheumatology, Royal North Shore Hospital</s1>
<s2>St. Leonards, NSW</s2>
<s3>AUS</s3>
</fA14>
<fA14 i1="15"><s1>Musculoskeletal Health and Arthritis Program, University of Toronto, Toronto Western Hospital</s1>
<s2>Toronto</s2>
<s3>CAN</s3>
</fA14>
<fA14 i1="16"><s1>Institute of Rheumatology and Clinic of Rheumatology, Charles University</s1>
<s2>Prague</s2>
<s3>CZE</s3>
</fA14>
<fA14 i1="17"><s1>University of Texas, M.D. Anderson Cancer Center</s1>
<s2>Houston, Texas</s2>
<s3>USA</s3>
</fA14>
<fA14 i1="18"><s1>Department of Orthopaedics, Ferrara University</s1>
<s2>Ferrara</s2>
<s3>ITA</s3>
</fA14>
<fA20><s1>1432-1435</s1>
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<fA21><s1>2007</s1>
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<s2>C</s2>
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<fA61><s0>A</s0>
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<fC01 i1="01" l="ENG"><s0>Objective. Time to theoretical indication of joint replacement surgery has been proposed as a primary outcome for potential structure-modifying interventions for osteoarthritis (OA). The objectives of this OMERACT/OARSI Working Group were to identify pain, physical function, and structure states that represent the progression from early to late disease for individuals with OA of the hip and knee, and to create a composite measure of these 3 domains to define states of OA severity and a surrogate measure of "need for joint replacement surgery." Methods. For pain, focus groups and one-on-one interviews were used. For function, Rasch analysis was performed on existing indices - the Hip Dysfunction and Osteoarthritis Outcome Score (HOOS) and the Knee injury and Osteoarthritis Outcome Score (KOOS), each of which subsumes the Western Ontario and McMaster University Osteoarthritis Index (WOMAC) questions. For structure, a comparison of existing indices (Kellgren-Lawrence, OARSI stages, and joint space width) was performed for the hip and the knee. Results. For pain, key features of pain that are most distressing to people with OA from early to late disease were identified. For function, the reduction of the number of items based on the existing indices continues. For structure, the analysis is also ongoing. Conclusion. Preliminary results were presented at OMERACT 8; the final objective will be to combine the 3 domains (pain, function, and structure) and to create a composite index that could define states of severity and "need for total joint replacement," which could be used to evaluate treatment response to disease-modifying drugs in OA clinical trials.</s0>
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<s5>07</s5>
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<s5>07</s5>
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<s5>08</s5>
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<s5>08</s5>
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<s5>09</s5>
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<s5>09</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Cadera</s0>
<s5>09</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Genou</s0>
<s5>13</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Knee</s0>
<s5>13</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Rodilla</s0>
<s5>13</s5>
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<s5>17</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG"><s0>Ontario</s0>
<s2>NG</s2>
<s5>17</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA"><s0>Ontario</s0>
<s2>NG</s2>
<s5>17</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE"><s0>Chirurgie orthopédique</s0>
<s5>30</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG"><s0>Orthopedic surgery</s0>
<s5>30</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA"><s0>Cirugía ortopédica</s0>
<s5>30</s5>
</fC03>
<fC03 i1="10" i2="X" l="FRE"><s0>Traitement</s0>
<s5>31</s5>
</fC03>
<fC03 i1="10" i2="X" l="ENG"><s0>Treatment</s0>
<s5>31</s5>
</fC03>
<fC03 i1="10" i2="X" l="SPA"><s0>Tratamiento</s0>
<s5>31</s5>
</fC03>
<fC03 i1="11" i2="X" l="FRE"><s0>Coxarthrose</s0>
<s4>INC</s4>
<s5>86</s5>
</fC03>
<fC03 i1="12" i2="X" l="FRE"><s0>Prothèse de hanche</s0>
<s4>CD</s4>
<s5>96</s5>
</fC03>
<fC03 i1="12" i2="X" l="ENG"><s0>Hip prosthesis</s0>
<s4>CD</s4>
<s5>96</s5>
</fC03>
<fC03 i1="12" i2="X" l="SPA"><s0>Prótesis de cadera</s0>
<s4>CD</s4>
<s5>96</s5>
</fC03>
<fC03 i1="13" i2="X" l="FRE"><s0>Gonarthrose</s0>
<s4>CD</s4>
<s5>97</s5>
</fC03>
<fC03 i1="13" i2="X" l="ENG"><s0>Knee osteoarthritis</s0>
<s4>CD</s4>
<s5>97</s5>
</fC03>
<fC03 i1="14" i2="X" l="FRE"><s0>Interligne articulaire</s0>
<s4>CD</s4>
<s5>98</s5>
</fC03>
<fC03 i1="14" i2="X" l="ENG"><s0>Joint space</s0>
<s4>CD</s4>
<s5>98</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Canada</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Canada</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Canadá</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Amérique du Nord</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>North America</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>America del norte</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Amérique</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>America</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>America</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Arthropathie</s0>
<s5>37</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Arthropathy</s0>
<s5>37</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Artropatía</s0>
<s5>37</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Maladie dégénérative</s0>
<s5>38</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Degenerative disease</s0>
<s5>38</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Enfermedad degenerativa</s0>
<s5>38</s5>
</fC07>
<fC07 i1="06" i2="X" l="FRE"><s0>Système ostéoarticulaire pathologie</s0>
<s5>39</s5>
</fC07>
<fC07 i1="06" i2="X" l="ENG"><s0>Diseases of the osteoarticular system</s0>
<s5>39</s5>
</fC07>
<fC07 i1="06" i2="X" l="SPA"><s0>Sistema osteoarticular patología</s0>
<s5>39</s5>
</fC07>
<fN21><s1>204</s1>
</fN21>
<fN44 i1="01"><s1>OTO</s1>
</fN44>
<fN82><s1>OTO</s1>
</fN82>
</pA>
<pR><fA30 i1="01" i2="1" l="ENG"><s1>OMERACT 8. Workshop</s1>
<s3>St. Julian's Bay MLT</s3>
<s4>2006-05-10</s4>
</fA30>
</pR>
</standard>
<server><NO>PASCAL 07-0314512 INIST</NO>
<ET>OMERACT/OARSI initiative to define states of severity and indication for joint replacement in hip and knee osteoarthritis</ET>
<AU>GOSSEC (Laure); HAWKER (Gillian); DAVIS (Aileen M.); MAILLEFERT (Jean Francis); LOHMANDER (L. Stefan); ALTMAN (Roy); CIBERE (Jolanda); CONAGHAN (Philip G.); HOCHBERG (Marc C.); JORDAN (Joanne M.); KATZ (Jeffrey N.); MARCH (Lyn); MAHOMED (Nizar); PAVELKA (Karel); ROOS (Ewa M.); SUAREZ-ALMAZOR (Maria E.); ZANOLI (Gustavo); DOUGADOS (Maxime)</AU>
<AF>Medicine Faculty, Paris 5 René Descartes University/France (1 aut.); AP-HP, Cochin Hospital. Department of Rheumatology B/Paris/France (1 aut.); Division of Rheumatology, Department of Medicine, Women's College Hospital/France (2 aut.); Clinical Epidemiology and Health Care Research Program, Department of Health Policy, Management and Evaluation, Faculty of Medicine, University of Toronto/Toronto/Canada (2 aut., 3 aut.); Dijon University Hospital, and INSERM ERM 0207, University of Burgundy/Dijon/France (4 aut.); Outcomes and Population Health, Toronto Western Research Institute/Canada; Department of Orthopaedics, Clinical Sciences Lund, Lund University/Lund/Suède; Division of Rheumatology and Immunology, University of California at Los Angeles/Los Angeles, California/Etats-Unis; Division of Rheumatology, Department of Medicine, University of British Columbia, Arthritis Research Centre of Canada/Vancouver/Canada; Academic Unit of Musculoskeletal Disease, University of Leeds/Leeds/Royaume-Uni; Division of Rheumatology and Clinical Immunology, University of Maryland School of Medicine/Baltimore, Maryland/Etats-Unis; Departments of Medicine and Orthopaedics, Thurston Arthritis Research Center, University of North Carolina/Chapel Hill, North Carolina/Etats-Unis; Section of Clinical Sciences, Division of Rheumatology, Immunology and Allergy, and Department of Orthopaedic Surgery, Brigham and Women's Hospital/Boston, Massachusetts/Etats-Unis; University of Sydney, Florance and Cope Professorial Department of Rheumatology, Royal North Shore Hospital/St. Leonards, NSW/Australie; Musculoskeletal Health and Arthritis Program, University of Toronto, Toronto Western Hospital/Toronto/Canada; Institute of Rheumatology and Clinic of Rheumatology, Charles University/Prague/Tchèque, République; University of Texas, M.D. Anderson Cancer Center/Houston, Texas/Etats-Unis; Department of Orthopaedics, Ferrara University/Ferrara/Italie</AF>
<DT>Publication en série; Congrès; Niveau analytique</DT>
<SO>Journal of rheumatology; ISSN 0315-162X; Coden JRHUA9; Canada; Da. 2007; Vol. 34; No. 6; Pp. 1432-1435; Bibl. 12 ref.</SO>
<LA>Anglais</LA>
<EA>Objective. Time to theoretical indication of joint replacement surgery has been proposed as a primary outcome for potential structure-modifying interventions for osteoarthritis (OA). The objectives of this OMERACT/OARSI Working Group were to identify pain, physical function, and structure states that represent the progression from early to late disease for individuals with OA of the hip and knee, and to create a composite measure of these 3 domains to define states of OA severity and a surrogate measure of "need for joint replacement surgery." Methods. For pain, focus groups and one-on-one interviews were used. For function, Rasch analysis was performed on existing indices - the Hip Dysfunction and Osteoarthritis Outcome Score (HOOS) and the Knee injury and Osteoarthritis Outcome Score (KOOS), each of which subsumes the Western Ontario and McMaster University Osteoarthritis Index (WOMAC) questions. For structure, a comparison of existing indices (Kellgren-Lawrence, OARSI stages, and joint space width) was performed for the hip and the knee. Results. For pain, key features of pain that are most distressing to people with OA from early to late disease were identified. For function, the reduction of the number of items based on the existing indices continues. For structure, the analysis is also ongoing. Conclusion. Preliminary results were presented at OMERACT 8; the final objective will be to combine the 3 domains (pain, function, and structure) and to create a composite index that could define states of severity and "need for total joint replacement," which could be used to evaluate treatment response to disease-modifying drugs in OA clinical trials.</EA>
<CC>002B15E; 002B25I; 002B15I</CC>
<FD>Indication; Articulation coxofémorale; Hanche; Genou; Arthrose; Douleur; Pronostic; Ontario; Chirurgie orthopédique; Traitement; Coxarthrose; Prothèse de hanche; Gonarthrose; Interligne articulaire</FD>
<FG>Canada; Amérique du Nord; Amérique; Arthropathie; Maladie dégénérative; Système ostéoarticulaire pathologie</FG>
<ED>Indication; Hip joint; Hip; Knee; Osteoarthritis; Pain; Prognosis; Ontario; Orthopedic surgery; Treatment; Hip prosthesis; Knee osteoarthritis; Joint space</ED>
<EG>Canada; North America; America; Arthropathy; Degenerative disease; Diseases of the osteoarticular system</EG>
<SD>Indicación; Articulación coxofemoral; Cadera; Rodilla; Artrosis; Dolor; Pronóstico; Ontario; Cirugía ortopédica; Tratamiento; Prótesis de cadera</SD>
<LO>INIST-16024.354000149923590350</LO>
<ID>07-0314512</ID>
</server>
</inist>
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OMERACT/OARSI initiative to define states of severity and indication for joint replacement in hip and knee osteoarthritis

OMERACT/OARSI initiative to define states of severity and indication for joint replacement in hip and knee osteoarthritis

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