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Consensus statement on definitions of disease, end points, and therapeutic response for pemphigus

Identifieur interne : 003542 ( PascalFrancis/Corpus ); précédent : 003541; suivant : 003543

Consensus statement on definitions of disease, end points, and therapeutic response for pemphigus

Auteurs : Dedee F. Murrell ; Sarah Dick ; A. R. Ahmed ; Masayuki Amagai ; Maria A. Barnadas ; Luca Borradori ; Jean-Claude Bystryn ; Giuseppe Cianchini ; Luis Diaz ; David Fivenson ; Russell Hall ; Karen E. Harman ; Takashi Hashimoto ; Michael Hertl ; Nico Hunzelmann ; Pilar Iranzo ; Pascal Joly ; Marcel F. Jonkman ; Yasuo Kitajima ; Neil J. Korman ; Linda K. Martin ; Daniel Mimouni ; Amit G. Pandya ; Aimee S. Payne ; David Rubenstein ; Hiroshi Shimizu ; Animesh A. Sinha ; David Sirois ; Detlef Zillikens ; Victoria P. Werth

Source :

RBID : Pascal:08-0281029

Descripteurs français

English descriptors

Abstract

Our scientific knowledge of pemphigus has dramatically progressed in recent years. However, despite the availability of various therapeutic options for the treatment of inflammatory diseases, only a few multicenter controlled trials have helped to define effective therapies in pemphigus. A major obstacle in comparing therapeutic outcomes between centers is the lack of generally accepted definitions and measurements for the clinical evaluation of patients with pemphigus. Common terms and end points of pemphigus are needed so that experts in the field can accurately measure and assess disease extent, activity, severity, and therapeutic response, and thus facilitate and advance clinical trials. This consensus statement from the International Pemphigus Committee represents 2 years of collaborative efforts to attain mutually acceptable common definitions for pemphigus. These should assist in development of consistent reporting of outcomes in future studies.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

pA  
A01 01  1    @0 0190-9622
A02 01      @0 JAADDB
A03   1    @0 J. Am. Acad. Dermatol.
A05       @2 58
A06       @2 6
A08 01  1  ENG  @1 Consensus statement on definitions of disease, end points, and therapeutic response for pemphigus
A11 01  1    @1 MURRELL (Dedee F.)
A11 02  1    @1 DICK (Sarah)
A11 03  1    @1 AHMED (A. R.)
A11 04  1    @1 AMAGAI (Masayuki)
A11 05  1    @1 BARNADAS (Maria A.)
A11 06  1    @1 BORRADORI (Luca)
A11 07  1    @1 BYSTRYN (Jean-Claude)
A11 08  1    @1 CIANCHINI (Giuseppe)
A11 09  1    @1 DIAZ (Luis)
A11 10  1    @1 FIVENSON (David)
A11 11  1    @1 HALL (Russell)
A11 12  1    @1 HARMAN (Karen E.)
A11 13  1    @1 HASHIMOTO (Takashi)
A11 14  1    @1 HERTL (Michael)
A11 15  1    @1 HUNZELMANN (Nico)
A11 16  1    @1 IRANZO (Pilar)
A11 17  1    @1 JOLY (Pascal)
A11 18  1    @1 JONKMAN (Marcel F.)
A11 19  1    @1 KITAJIMA (Yasuo)
A11 20  1    @1 KORMAN (Neil J.)
A11 21  1    @1 MARTIN (Linda K.)
A11 22  1    @1 MIMOUNI (Daniel)
A11 23  1    @1 PANDYA (Amit G.)
A11 24  1    @1 PAYNE (Aimee S.)
A11 25  1    @1 RUBENSTEIN (David)
A11 26  1    @1 SHIMIZU (Hiroshi)
A11 27  1    @1 SINHA (Animesh A.)
A11 28  1    @1 SIROIS (David)
A11 29  1    @1 ZILLIKENS (Detlef)
A11 30  1    @1 WERTH (Victoria P.)
A14 01      @1 Departments of Dermatology at St George Hospital, University of NSW @2 Sydney @3 AUS @Z 1 aut. @Z 21 aut.
A14 02      @1 University of Pennsylvania @3 USA @Z 2 aut. @Z 24 aut. @Z 30 aut.
A14 03      @1 Department of Medicine, Center for Blistering Diseases, New England Baptist Hospital @2 Boston @3 USA @Z 3 aut.
A14 04      @1 Keio University School of Medicine @2 Tokyo @3 JPN @Z 4 aut.
A14 05      @1 Hospital de la Santa Creu i Sant Pau @2 Barcelona @3 ESP @Z 5 aut.
A14 06      @1 Hôpital Cantonal Universitaire @2 Geneva @3 CHE @Z 6 aut.
A14 07      @1 New York University Medical Center @3 USA @Z 7 aut.
A14 08      @1 Immunodermatology Department, Istituto Dermopatico dell'lmmacolata, I.R.C.C.S., Via dei Monti di Creta @2 Rome @3 ITA @Z 8 aut.
A14 09      @1 University of North Carolina @2 Chapel Hill @3 USA @Z 9 aut. @Z 25 aut.
A14 10      @1 Private Practice @2 Ann Arbor @3 USA @Z 10 aut.
A14 11      @1 Division of Dermatology, Duke Medical Center @2 Durham @3 USA @Z 11 aut.
A14 12      @1 University Hospitals Leicester @3 GBR @Z 12 aut.
A14 13      @1 Kurume University School of Medicine @3 JPN @Z 13 aut.
A14 14      @1 Universitätsklinikum GieBen und Marburg GmbH @3 DEU @Z 14 aut.
A14 15      @1 Universitätshautklinik Köln @3 DEU @Z 15 aut.
A14 16      @1 Hospital Clínic, Universitat de Barcelona @3 ESP @Z 16 aut.
A14 17      @1 Clinique Dermatologique, Hopital Charles Nicolle @2 Rouen @3 FRA @Z 17 aut.
A14 18      @1 University Medical Center Groningen, University of Groningen @3 NLD @Z 18 aut.
A14 19      @1 Gifu University School of Medicine @3 JPN @Z 19 aut.
A14 20      @1 University Hospitals Case Medical Center @2 Cleveland @3 USA @Z 20 aut.
A14 21      @1 Rabin Medical Center @2 Petah-Tikva @3 ISR @Z 22 aut.
A14 22      @1 University of Texas Southwestern Medical Center @2 Dallas @3 USA @Z 23 aut.
A14 23      @1 Hokkaido University Graduate School of Medicine @2 Sapporo @3 JPN @Z 26 aut.
A14 24      @1 Center for Investigative Dermatology, Division of Dermatology and Cutaneous Sciences, Michigan State University @2 East Lansing @3 USA @Z 27 aut.
A14 25      @1 Department of Oral Medicine, New York University College of Dentistry @3 USA @Z 28 aut.
A20       @1 1043-1046
A21       @1 2008
A23 01      @0 ENG
A43 01      @1 INIST @2 18387 @5 354000195963870150
A44       @0 0000 @1 © 2008 INIST-CNRS. All rights reserved.
A45       @0 1 ref.
A47 01  1    @0 08-0281029
A60       @1 P
A61       @0 A
A64 01  1    @0 Journal of the American Academy of Dermatology
A66 01      @0 USA
C01 01    ENG  @0 Our scientific knowledge of pemphigus has dramatically progressed in recent years. However, despite the availability of various therapeutic options for the treatment of inflammatory diseases, only a few multicenter controlled trials have helped to define effective therapies in pemphigus. A major obstacle in comparing therapeutic outcomes between centers is the lack of generally accepted definitions and measurements for the clinical evaluation of patients with pemphigus. Common terms and end points of pemphigus are needed so that experts in the field can accurately measure and assess disease extent, activity, severity, and therapeutic response, and thus facilitate and advance clinical trials. This consensus statement from the International Pemphigus Committee represents 2 years of collaborative efforts to attain mutually acceptable common definitions for pemphigus. These should assist in development of consistent reporting of outcomes in future studies.
C02 01  X    @0 002B08E
C02 02  X    @0 002B01
C03 01  X  FRE  @0 Pemphigus @5 01
C03 01  X  ENG  @0 Pemphigus @5 01
C03 01  X  SPA  @0 Pénfigo @5 01
C03 02  X  FRE  @0 Définition @5 09
C03 02  X  ENG  @0 Definition @5 09
C03 02  X  SPA  @0 Definición @5 09
C03 03  X  FRE  @0 Extrémité @5 10
C03 03  X  ENG  @0 End @5 10
C03 03  X  SPA  @0 Extremidad @5 10
C03 04  X  FRE  @0 Traitement @5 11
C03 04  X  ENG  @0 Treatment @5 11
C03 04  X  SPA  @0 Tratamiento @5 11
C03 05  X  FRE  @0 Dermatologie @5 12
C03 05  X  ENG  @0 Dermatology @5 12
C03 05  X  SPA  @0 Dermatología @5 12
C07 01  X  FRE  @0 Maladie autoimmune @5 37
C07 01  X  ENG  @0 Autoimmune disease @5 37
C07 01  X  SPA  @0 Enfermedad autoinmune @5 37
C07 02  X  FRE  @0 Dermatose bulleuse @5 38
C07 02  X  ENG  @0 Bullous dermatosis @5 38
C07 02  X  SPA  @0 Dermatosis bulosa @5 38
C07 03  X  FRE  @0 Pathologie de la peau @5 39
C07 03  X  ENG  @0 Skin disease @5 39
C07 03  X  SPA  @0 Piel patología @5 39
C07 04  X  FRE  @0 Immunopathologie @5 40
C07 04  X  ENG  @0 Immunopathology @5 40
C07 04  X  SPA  @0 Inmunopatología @5 40
N21       @1 175
N44 01      @1 OTO
N82       @1 OTO

Format Inist (serveur)

NO : PASCAL 08-0281029 INIST
ET : Consensus statement on definitions of disease, end points, and therapeutic response for pemphigus
AU : MURRELL (Dedee F.); DICK (Sarah); AHMED (A. R.); AMAGAI (Masayuki); BARNADAS (Maria A.); BORRADORI (Luca); BYSTRYN (Jean-Claude); CIANCHINI (Giuseppe); DIAZ (Luis); FIVENSON (David); HALL (Russell); HARMAN (Karen E.); HASHIMOTO (Takashi); HERTL (Michael); HUNZELMANN (Nico); IRANZO (Pilar); JOLY (Pascal); JONKMAN (Marcel F.); KITAJIMA (Yasuo); KORMAN (Neil J.); MARTIN (Linda K.); MIMOUNI (Daniel); PANDYA (Amit G.); PAYNE (Aimee S.); RUBENSTEIN (David); SHIMIZU (Hiroshi); SINHA (Animesh A.); SIROIS (David); ZILLIKENS (Detlef); WERTH (Victoria P.)
AF : Departments of Dermatology at St George Hospital, University of NSW/Sydney/Australie (1 aut., 21 aut.); University of Pennsylvania/Etats-Unis (2 aut., 24 aut., 30 aut.); Department of Medicine, Center for Blistering Diseases, New England Baptist Hospital/Boston/Etats-Unis (3 aut.); Keio University School of Medicine/Tokyo/Japon (4 aut.); Hospital de la Santa Creu i Sant Pau/Barcelona/Espagne (5 aut.); Hôpital Cantonal Universitaire/Geneva/Suisse (6 aut.); New York University Medical Center/Etats-Unis (7 aut.); Immunodermatology Department, Istituto Dermopatico dell'lmmacolata, I.R.C.C.S., Via dei Monti di Creta/Rome/Italie (8 aut.); University of North Carolina/Chapel Hill/Etats-Unis (9 aut., 25 aut.); Private Practice/Ann Arbor/Etats-Unis (10 aut.); Division of Dermatology, Duke Medical Center/Durham/Etats-Unis (11 aut.); University Hospitals Leicester/Royaume-Uni (12 aut.); Kurume University School of Medicine/Japon (13 aut.); Universitätsklinikum GieBen und Marburg GmbH/Allemagne (14 aut.); Universitätshautklinik Köln/Allemagne (15 aut.); Hospital Clínic, Universitat de Barcelona/Espagne (16 aut.); Clinique Dermatologique, Hopital Charles Nicolle/Rouen/France (17 aut.); University Medical Center Groningen, University of Groningen/Pays-Bas (18 aut.); Gifu University School of Medicine/Japon (19 aut.); University Hospitals Case Medical Center/Cleveland/Etats-Unis (20 aut.); Rabin Medical Center/Petah-Tikva/Israël (22 aut.); University of Texas Southwestern Medical Center/Dallas/Etats-Unis (23 aut.); Hokkaido University Graduate School of Medicine/Sapporo/Japon (26 aut.); Center for Investigative Dermatology, Division of Dermatology and Cutaneous Sciences, Michigan State University/East Lansing/Etats-Unis (27 aut.); Department of Oral Medicine, New York University College of Dentistry/Etats-Unis (28 aut.)
DT : Publication en série; Niveau analytique
SO : Journal of the American Academy of Dermatology; ISSN 0190-9622; Coden JAADDB; Etats-Unis; Da. 2008; Vol. 58; No. 6; Pp. 1043-1046; Bibl. 1 ref.
LA : Anglais
EA : Our scientific knowledge of pemphigus has dramatically progressed in recent years. However, despite the availability of various therapeutic options for the treatment of inflammatory diseases, only a few multicenter controlled trials have helped to define effective therapies in pemphigus. A major obstacle in comparing therapeutic outcomes between centers is the lack of generally accepted definitions and measurements for the clinical evaluation of patients with pemphigus. Common terms and end points of pemphigus are needed so that experts in the field can accurately measure and assess disease extent, activity, severity, and therapeutic response, and thus facilitate and advance clinical trials. This consensus statement from the International Pemphigus Committee represents 2 years of collaborative efforts to attain mutually acceptable common definitions for pemphigus. These should assist in development of consistent reporting of outcomes in future studies.
CC : 002B08E; 002B01
FD : Pemphigus; Définition; Extrémité; Traitement; Dermatologie
FG : Maladie autoimmune; Dermatose bulleuse; Pathologie de la peau; Immunopathologie
ED : Pemphigus; Definition; End; Treatment; Dermatology
EG : Autoimmune disease; Bullous dermatosis; Skin disease; Immunopathology
SD : Pénfigo; Definición; Extremidad; Tratamiento; Dermatología
LO : INIST-18387.354000195963870150
ID : 08-0281029

Links to Exploration step

Pascal:08-0281029

Le document en format XML

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<name sortKey="Kitajima, Yasuo" sort="Kitajima, Yasuo" uniqKey="Kitajima Y" first="Yasuo" last="Kitajima">Yasuo Kitajima</name>
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<name sortKey="Korman, Neil J" sort="Korman, Neil J" uniqKey="Korman N" first="Neil J." last="Korman">Neil J. Korman</name>
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<name sortKey="Martin, Linda K" sort="Martin, Linda K" uniqKey="Martin L" first="Linda K." last="Martin">Linda K. Martin</name>
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<name sortKey="Mimouni, Daniel" sort="Mimouni, Daniel" uniqKey="Mimouni D" first="Daniel" last="Mimouni">Daniel Mimouni</name>
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</affiliation>
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<author>
<name sortKey="Pandya, Amit G" sort="Pandya, Amit G" uniqKey="Pandya A" first="Amit G." last="Pandya">Amit G. Pandya</name>
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<name sortKey="Payne, Aimee S" sort="Payne, Aimee S" uniqKey="Payne A" first="Aimee S." last="Payne">Aimee S. Payne</name>
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<author>
<name sortKey="Rubenstein, David" sort="Rubenstein, David" uniqKey="Rubenstein D" first="David" last="Rubenstein">David Rubenstein</name>
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</inist:fA14>
</affiliation>
</author>
<author>
<name sortKey="Zillikens, Detlef" sort="Zillikens, Detlef" uniqKey="Zillikens D" first="Detlef" last="Zillikens">Detlef Zillikens</name>
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<author>
<name sortKey="Werth, Victoria P" sort="Werth, Victoria P" uniqKey="Werth V" first="Victoria P." last="Werth">Victoria P. Werth</name>
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<inist:fA14 i1="02">
<s1>University of Pennsylvania</s1>
<s3>USA</s3>
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<sZ>24 aut.</sZ>
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<title xml:lang="en" level="a">Consensus statement on definitions of disease, end points, and therapeutic response for pemphigus</title>
<author>
<name sortKey="Murrell, Dedee F" sort="Murrell, Dedee F" uniqKey="Murrell D" first="Dedee F." last="Murrell">Dedee F. Murrell</name>
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<inist:fA14 i1="01">
<s1>Departments of Dermatology at St George Hospital, University of NSW</s1>
<s2>Sydney</s2>
<s3>AUS</s3>
<sZ>1 aut.</sZ>
<sZ>21 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author>
<name sortKey="Dick, Sarah" sort="Dick, Sarah" uniqKey="Dick S" first="Sarah" last="Dick">Sarah Dick</name>
<affiliation>
<inist:fA14 i1="02">
<s1>University of Pennsylvania</s1>
<s3>USA</s3>
<sZ>2 aut.</sZ>
<sZ>24 aut.</sZ>
<sZ>30 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author>
<name sortKey="Ahmed, A R" sort="Ahmed, A R" uniqKey="Ahmed A" first="A. R." last="Ahmed">A. R. Ahmed</name>
<affiliation>
<inist:fA14 i1="03">
<s1>Department of Medicine, Center for Blistering Diseases, New England Baptist Hospital</s1>
<s2>Boston</s2>
<s3>USA</s3>
<sZ>3 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author>
<name sortKey="Amagai, Masayuki" sort="Amagai, Masayuki" uniqKey="Amagai M" first="Masayuki" last="Amagai">Masayuki Amagai</name>
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<inist:fA14 i1="04">
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</inist:fA14>
</affiliation>
</author>
<author>
<name sortKey="Barnadas, Maria A" sort="Barnadas, Maria A" uniqKey="Barnadas M" first="Maria A." last="Barnadas">Maria A. Barnadas</name>
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</affiliation>
</author>
<author>
<name sortKey="Borradori, Luca" sort="Borradori, Luca" uniqKey="Borradori L" first="Luca" last="Borradori">Luca Borradori</name>
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</author>
<author>
<name sortKey="Bystryn, Jean Claude" sort="Bystryn, Jean Claude" uniqKey="Bystryn J" first="Jean-Claude" last="Bystryn">Jean-Claude Bystryn</name>
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<s1>New York University Medical Center</s1>
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</author>
<author>
<name sortKey="Cianchini, Giuseppe" sort="Cianchini, Giuseppe" uniqKey="Cianchini G" first="Giuseppe" last="Cianchini">Giuseppe Cianchini</name>
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</inist:fA14>
</affiliation>
</author>
<author>
<name sortKey="Diaz, Luis" sort="Diaz, Luis" uniqKey="Diaz L" first="Luis" last="Diaz">Luis Diaz</name>
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<inist:fA14 i1="09">
<s1>University of North Carolina</s1>
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<s3>USA</s3>
<sZ>9 aut.</sZ>
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</inist:fA14>
</affiliation>
</author>
<author>
<name sortKey="Fivenson, David" sort="Fivenson, David" uniqKey="Fivenson D" first="David" last="Fivenson">David Fivenson</name>
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<inist:fA14 i1="10">
<s1>Private Practice</s1>
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</affiliation>
</author>
<author>
<name sortKey="Hall, Russell" sort="Hall, Russell" uniqKey="Hall R" first="Russell" last="Hall">Russell Hall</name>
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</affiliation>
</author>
<author>
<name sortKey="Harman, Karen E" sort="Harman, Karen E" uniqKey="Harman K" first="Karen E." last="Harman">Karen E. Harman</name>
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<inist:fA14 i1="12">
<s1>University Hospitals Leicester</s1>
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</inist:fA14>
</affiliation>
</author>
<author>
<name sortKey="Hashimoto, Takashi" sort="Hashimoto, Takashi" uniqKey="Hashimoto T" first="Takashi" last="Hashimoto">Takashi Hashimoto</name>
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<inist:fA14 i1="13">
<s1>Kurume University School of Medicine</s1>
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</author>
<author>
<name sortKey="Hertl, Michael" sort="Hertl, Michael" uniqKey="Hertl M" first="Michael" last="Hertl">Michael Hertl</name>
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<inist:fA14 i1="14">
<s1>Universitätsklinikum GieBen und Marburg GmbH</s1>
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</affiliation>
</author>
<author>
<name sortKey="Hunzelmann, Nico" sort="Hunzelmann, Nico" uniqKey="Hunzelmann N" first="Nico" last="Hunzelmann">Nico Hunzelmann</name>
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<inist:fA14 i1="15">
<s1>Universitätshautklinik Köln</s1>
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</affiliation>
</author>
<author>
<name sortKey="Iranzo, Pilar" sort="Iranzo, Pilar" uniqKey="Iranzo P" first="Pilar" last="Iranzo">Pilar Iranzo</name>
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<inist:fA14 i1="16">
<s1>Hospital Clínic, Universitat de Barcelona</s1>
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</author>
<author>
<name sortKey="Joly, Pascal" sort="Joly, Pascal" uniqKey="Joly P" first="Pascal" last="Joly">Pascal Joly</name>
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<inist:fA14 i1="17">
<s1>Clinique Dermatologique, Hopital Charles Nicolle</s1>
<s2>Rouen</s2>
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<sZ>17 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author>
<name sortKey="Jonkman, Marcel F" sort="Jonkman, Marcel F" uniqKey="Jonkman M" first="Marcel F." last="Jonkman">Marcel F. Jonkman</name>
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<inist:fA14 i1="18">
<s1>University Medical Center Groningen, University of Groningen</s1>
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</affiliation>
</author>
<author>
<name sortKey="Kitajima, Yasuo" sort="Kitajima, Yasuo" uniqKey="Kitajima Y" first="Yasuo" last="Kitajima">Yasuo Kitajima</name>
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<inist:fA14 i1="19">
<s1>Gifu University School of Medicine</s1>
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</inist:fA14>
</affiliation>
</author>
<author>
<name sortKey="Korman, Neil J" sort="Korman, Neil J" uniqKey="Korman N" first="Neil J." last="Korman">Neil J. Korman</name>
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<inist:fA14 i1="20">
<s1>University Hospitals Case Medical Center</s1>
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</affiliation>
</author>
<author>
<name sortKey="Martin, Linda K" sort="Martin, Linda K" uniqKey="Martin L" first="Linda K." last="Martin">Linda K. Martin</name>
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</affiliation>
</author>
<author>
<name sortKey="Mimouni, Daniel" sort="Mimouni, Daniel" uniqKey="Mimouni D" first="Daniel" last="Mimouni">Daniel Mimouni</name>
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<s1>Rabin Medical Center</s1>
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</affiliation>
</author>
<author>
<name sortKey="Pandya, Amit G" sort="Pandya, Amit G" uniqKey="Pandya A" first="Amit G." last="Pandya">Amit G. Pandya</name>
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<inist:fA14 i1="22">
<s1>University of Texas Southwestern Medical Center</s1>
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</affiliation>
</author>
<author>
<name sortKey="Payne, Aimee S" sort="Payne, Aimee S" uniqKey="Payne A" first="Aimee S." last="Payne">Aimee S. Payne</name>
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<s1>University of Pennsylvania</s1>
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</author>
<author>
<name sortKey="Rubenstein, David" sort="Rubenstein, David" uniqKey="Rubenstein D" first="David" last="Rubenstein">David Rubenstein</name>
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<inist:fA14 i1="09">
<s1>University of North Carolina</s1>
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</inist:fA14>
</affiliation>
</author>
<author>
<name sortKey="Shimizu, Hiroshi" sort="Shimizu, Hiroshi" uniqKey="Shimizu H" first="Hiroshi" last="Shimizu">Hiroshi Shimizu</name>
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</affiliation>
</author>
<author>
<name sortKey="Sinha, Animesh A" sort="Sinha, Animesh A" uniqKey="Sinha A" first="Animesh A." last="Sinha">Animesh A. Sinha</name>
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<s1>Center for Investigative Dermatology, Division of Dermatology and Cutaneous Sciences, Michigan State University</s1>
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</affiliation>
</author>
<author>
<name sortKey="Sirois, David" sort="Sirois, David" uniqKey="Sirois D" first="David" last="Sirois">David Sirois</name>
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<s1>Department of Oral Medicine, New York University College of Dentistry</s1>
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</affiliation>
</author>
<author>
<name sortKey="Zillikens, Detlef" sort="Zillikens, Detlef" uniqKey="Zillikens D" first="Detlef" last="Zillikens">Detlef Zillikens</name>
</author>
<author>
<name sortKey="Werth, Victoria P" sort="Werth, Victoria P" uniqKey="Werth V" first="Victoria P." last="Werth">Victoria P. Werth</name>
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<inist:fA14 i1="02">
<s1>University of Pennsylvania</s1>
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</analytic>
<series>
<title level="j" type="main">Journal of the American Academy of Dermatology</title>
<title level="j" type="abbreviated">J. Am. Acad. Dermatol.</title>
<idno type="ISSN">0190-9622</idno>
<imprint>
<date when="2008">2008</date>
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<title level="j" type="main">Journal of the American Academy of Dermatology</title>
<title level="j" type="abbreviated">J. Am. Acad. Dermatol.</title>
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<keywords scheme="KwdEn" xml:lang="en">
<term>Definition</term>
<term>Dermatology</term>
<term>End</term>
<term>Pemphigus</term>
<term>Treatment</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr">
<term>Pemphigus</term>
<term>Définition</term>
<term>Extrémité</term>
<term>Traitement</term>
<term>Dermatologie</term>
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<front>
<div type="abstract" xml:lang="en">Our scientific knowledge of pemphigus has dramatically progressed in recent years. However, despite the availability of various therapeutic options for the treatment of inflammatory diseases, only a few multicenter controlled trials have helped to define effective therapies in pemphigus. A major obstacle in comparing therapeutic outcomes between centers is the lack of generally accepted definitions and measurements for the clinical evaluation of patients with pemphigus. Common terms and end points of pemphigus are needed so that experts in the field can accurately measure and assess disease extent, activity, severity, and therapeutic response, and thus facilitate and advance clinical trials. This consensus statement from the International Pemphigus Committee represents 2 years of collaborative efforts to attain mutually acceptable common definitions for pemphigus. These should assist in development of consistent reporting of outcomes in future studies.</div>
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<fA14 i1="03">
<s1>Department of Medicine, Center for Blistering Diseases, New England Baptist Hospital</s1>
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<s1>Keio University School of Medicine</s1>
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<s1>Hospital de la Santa Creu i Sant Pau</s1>
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<s1>Hôpital Cantonal Universitaire</s1>
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<s1>Immunodermatology Department, Istituto Dermopatico dell'lmmacolata, I.R.C.C.S., Via dei Monti di Creta</s1>
<s2>Rome</s2>
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<fA14 i1="09">
<s1>University of North Carolina</s1>
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<sZ>9 aut.</sZ>
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<s1>Private Practice</s1>
<s2>Ann Arbor</s2>
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<sZ>10 aut.</sZ>
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<s1>Division of Dermatology, Duke Medical Center</s1>
<s2>Durham</s2>
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<sZ>11 aut.</sZ>
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<s1>University Hospitals Leicester</s1>
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<s1>Kurume University School of Medicine</s1>
<s3>JPN</s3>
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<s1>Universitätshautklinik Köln</s1>
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<s1>Clinique Dermatologique, Hopital Charles Nicolle</s1>
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<s1>University Medical Center Groningen, University of Groningen</s1>
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<s1>Gifu University School of Medicine</s1>
<s3>JPN</s3>
<sZ>19 aut.</sZ>
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<fA14 i1="20">
<s1>University Hospitals Case Medical Center</s1>
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<sZ>20 aut.</sZ>
</fA14>
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<s1>Rabin Medical Center</s1>
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<fA14 i1="22">
<s1>University of Texas Southwestern Medical Center</s1>
<s2>Dallas</s2>
<s3>USA</s3>
<sZ>23 aut.</sZ>
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<fA14 i1="23">
<s1>Hokkaido University Graduate School of Medicine</s1>
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<s3>JPN</s3>
<sZ>26 aut.</sZ>
</fA14>
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<s1>Center for Investigative Dermatology, Division of Dermatology and Cutaneous Sciences, Michigan State University</s1>
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<s3>USA</s3>
<sZ>27 aut.</sZ>
</fA14>
<fA14 i1="25">
<s1>Department of Oral Medicine, New York University College of Dentistry</s1>
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<s0>Our scientific knowledge of pemphigus has dramatically progressed in recent years. However, despite the availability of various therapeutic options for the treatment of inflammatory diseases, only a few multicenter controlled trials have helped to define effective therapies in pemphigus. A major obstacle in comparing therapeutic outcomes between centers is the lack of generally accepted definitions and measurements for the clinical evaluation of patients with pemphigus. Common terms and end points of pemphigus are needed so that experts in the field can accurately measure and assess disease extent, activity, severity, and therapeutic response, and thus facilitate and advance clinical trials. This consensus statement from the International Pemphigus Committee represents 2 years of collaborative efforts to attain mutually acceptable common definitions for pemphigus. These should assist in development of consistent reporting of outcomes in future studies.</s0>
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<s5>12</s5>
</fC03>
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<s5>12</s5>
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<s5>37</s5>
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<s5>38</s5>
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<s0>Dermatosis bulosa</s0>
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<s5>39</s5>
</fC07>
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<s5>39</s5>
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<ET>Consensus statement on definitions of disease, end points, and therapeutic response for pemphigus</ET>
<AU>MURRELL (Dedee F.); DICK (Sarah); AHMED (A. R.); AMAGAI (Masayuki); BARNADAS (Maria A.); BORRADORI (Luca); BYSTRYN (Jean-Claude); CIANCHINI (Giuseppe); DIAZ (Luis); FIVENSON (David); HALL (Russell); HARMAN (Karen E.); HASHIMOTO (Takashi); HERTL (Michael); HUNZELMANN (Nico); IRANZO (Pilar); JOLY (Pascal); JONKMAN (Marcel F.); KITAJIMA (Yasuo); KORMAN (Neil J.); MARTIN (Linda K.); MIMOUNI (Daniel); PANDYA (Amit G.); PAYNE (Aimee S.); RUBENSTEIN (David); SHIMIZU (Hiroshi); SINHA (Animesh A.); SIROIS (David); ZILLIKENS (Detlef); WERTH (Victoria P.)</AU>
<AF>Departments of Dermatology at St George Hospital, University of NSW/Sydney/Australie (1 aut., 21 aut.); University of Pennsylvania/Etats-Unis (2 aut., 24 aut., 30 aut.); Department of Medicine, Center for Blistering Diseases, New England Baptist Hospital/Boston/Etats-Unis (3 aut.); Keio University School of Medicine/Tokyo/Japon (4 aut.); Hospital de la Santa Creu i Sant Pau/Barcelona/Espagne (5 aut.); Hôpital Cantonal Universitaire/Geneva/Suisse (6 aut.); New York University Medical Center/Etats-Unis (7 aut.); Immunodermatology Department, Istituto Dermopatico dell'lmmacolata, I.R.C.C.S., Via dei Monti di Creta/Rome/Italie (8 aut.); University of North Carolina/Chapel Hill/Etats-Unis (9 aut., 25 aut.); Private Practice/Ann Arbor/Etats-Unis (10 aut.); Division of Dermatology, Duke Medical Center/Durham/Etats-Unis (11 aut.); University Hospitals Leicester/Royaume-Uni (12 aut.); Kurume University School of Medicine/Japon (13 aut.); Universitätsklinikum GieBen und Marburg GmbH/Allemagne (14 aut.); Universitätshautklinik Köln/Allemagne (15 aut.); Hospital Clínic, Universitat de Barcelona/Espagne (16 aut.); Clinique Dermatologique, Hopital Charles Nicolle/Rouen/France (17 aut.); University Medical Center Groningen, University of Groningen/Pays-Bas (18 aut.); Gifu University School of Medicine/Japon (19 aut.); University Hospitals Case Medical Center/Cleveland/Etats-Unis (20 aut.); Rabin Medical Center/Petah-Tikva/Israël (22 aut.); University of Texas Southwestern Medical Center/Dallas/Etats-Unis (23 aut.); Hokkaido University Graduate School of Medicine/Sapporo/Japon (26 aut.); Center for Investigative Dermatology, Division of Dermatology and Cutaneous Sciences, Michigan State University/East Lansing/Etats-Unis (27 aut.); Department of Oral Medicine, New York University College of Dentistry/Etats-Unis (28 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Journal of the American Academy of Dermatology; ISSN 0190-9622; Coden JAADDB; Etats-Unis; Da. 2008; Vol. 58; No. 6; Pp. 1043-1046; Bibl. 1 ref.</SO>
<LA>Anglais</LA>
<EA>Our scientific knowledge of pemphigus has dramatically progressed in recent years. However, despite the availability of various therapeutic options for the treatment of inflammatory diseases, only a few multicenter controlled trials have helped to define effective therapies in pemphigus. A major obstacle in comparing therapeutic outcomes between centers is the lack of generally accepted definitions and measurements for the clinical evaluation of patients with pemphigus. Common terms and end points of pemphigus are needed so that experts in the field can accurately measure and assess disease extent, activity, severity, and therapeutic response, and thus facilitate and advance clinical trials. This consensus statement from the International Pemphigus Committee represents 2 years of collaborative efforts to attain mutually acceptable common definitions for pemphigus. These should assist in development of consistent reporting of outcomes in future studies.</EA>
<CC>002B08E; 002B01</CC>
<FD>Pemphigus; Définition; Extrémité; Traitement; Dermatologie</FD>
<FG>Maladie autoimmune; Dermatose bulleuse; Pathologie de la peau; Immunopathologie</FG>
<ED>Pemphigus; Definition; End; Treatment; Dermatology</ED>
<EG>Autoimmune disease; Bullous dermatosis; Skin disease; Immunopathology</EG>
<SD>Pénfigo; Definición; Extremidad; Tratamiento; Dermatología</SD>
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