AustralieFrV1, PascalFrancis, Corpus, bibRecord, 002383

Is a gene-centric human proteome project the best way for proteomics to serve biology?

Identifieur interne : 002383 ( PascalFrancis/Corpus ); précédent : 002382; suivant : 002384

Is a gene-centric human proteome project the best way for proteomics to serve biology?

Auteurs : Thierry Rabilloud ; Denis Hochstrasser ; Richard J. Simpson

Source :

Proteomics : (Weinheim. Print) [ 1615-9853 ] ; 2010.

RBID : Pascal:10-0431596

Descripteurs français

Pascal (Inist)
- Homme, Gène, Protéome, Protéomique, Anticorps, Protéine.

English descriptors

KwdEn :
- Antibody, Gene, Human, Protein, Proteome, Proteomics.

Abstract

With the recent developments in proteomic technologies, a complete human proteome project (HPP) appears feasible for the first time. However, there is still debate as to how it should be designed and what it should encompass. In "proteomics speak", the debate revolves around the central question as to whether a gene-centric or a protein-centric proteomics approach is the most appropriate way forward. In this paper, we try to shed light on what these definitions mean, how large-scale proteomics such as a HPP can insert into the larger omics chorus, and what we can reasonably expect from a HPP in the way it has been proposed so far.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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Format Inist (serveur)

NO :	PASCAL 10-0431596 INIST
ET :	Is a gene-centric human proteome project the best way for proteomics to serve biology?
AU :	RABILLOUD (Thierry); HOCHSTRASSER (Denis); SIMPSON (Richard J.)
AF :	Biochemistry and Biophysics of Integrated Systems, UMR CNRS-CEA-UJF 5092, CEA Grenoble, iRTSV/BSBBSI/Grenoble/France (1 aut.); Department of Genetic and Laboratory Medicine, Laboratory Medicine Division, Geneva University, Geneva University Hospital and Swiss Centre of Applied Human Toxicology/Geneva/Suisse (2 aut.); Ludwig Institute for Cancer Research Inc, Royal Melbourne Hospital/Parkville/Australie (3 aut.)
DT :	Publication en série; Niveau analytique
SO :	Proteomics : (Weinheim. Print); ISSN 1615-9853; Allemagne; Da. 2010; Vol. 10; No. 17; Pp. 3067-3072; Bibl. 50 ref.
LA :	Anglais
EA :	With the recent developments in proteomic technologies, a complete human proteome project (HPP) appears feasible for the first time. However, there is still debate as to how it should be designed and what it should encompass. In "proteomics speak", the debate revolves around the central question as to whether a gene-centric or a protein-centric proteomics approach is the most appropriate way forward. In this paper, we try to shed light on what these definitions mean, how large-scale proteomics such as a HPP can insert into the larger omics chorus, and what we can reasonably expect from a HPP in the way it has been proposed so far.
CC :	002A02D10
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ED :	Human; Gene; Proteome; Proteomics; Antibody; Protein
SD :	Hombre; Gen; Proteoma; Proteómica; Anticuerpo; Proteína
LO :	INIST-27206.354000194246300010
ID :	10-0431596

Links to Exploration step

Pascal:10-0431596

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Is a gene-centric human proteome project the best way for proteomics to serve biology?

Is a gene-centric human proteome project the best way for proteomics to serve biology?

Source :

Descripteurs français

English descriptors

Abstract

Notice en format standard (ISO 2709)

Format Inist (serveur)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri