Depression in elderly persons subject to childhood maltreatment is not modulated by corpus callosum and hippocampal loss
Identifieur interne : 001787 ( PascalFrancis/Corpus ); précédent : 001786; suivant : 001788Depression in elderly persons subject to childhood maltreatment is not modulated by corpus callosum and hippocampal loss
Auteurs : Karen Ritchie ; Isabelle Jaussent ; Florence Portet ; Philippe Courtet ; Alain Malafosse ; Jerome Maller ; Chantal Meslin ; Alain Bonafe ; Emmanuelle Le Bars ; Nicolas Menjot De Champfleur ; Sylvaine Artero ; Marie-Laure AncelinSource :
- Journal of affective disorders [ 0165-0327 ] ; 2012.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
Childhood adversity has been observed to engender structural changes in the hippocampus and corpus callosum associated with increased risk for depression in childhood and early adulthood. This study investigated this association in the elderly. Corpus callosum area and hippocampal volume were measured from structural MRI in 427 community dwelling elderly. Information on childhood adversity was obtained in the course of a clinical examination using a questionnaire covering multiple aspects of abuse. Multivariate analyses found a significant increase in corpus callosum area and hippocampal volume in subjects exposed to mental disorder in parents and poverty, respectively. No association was found with childhood sexual and physical abuse.
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Format Inist (serveur)
NO : | FRANCIS 12-0440546 INIST |
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ET : | Depression in elderly persons subject to childhood maltreatment is not modulated by corpus callosum and hippocampal loss |
AU : | RITCHIE (Karen); JAUSSENT (Isabelle); PORTET (Florence); COURTET (Philippe); MALAFOSSE (Alain); MALLER (Jerome); MESLIN (Chantal); BONAFE (Alain); LE BARS (Emmanuelle); DE CHAMPFLEUR (Nicolas Menjot); ARTERO (Sylvaine); ANCELIN (Marie-Laure) |
AF : | Inserm, U1061/Montpellier, 34093/France (1 aut., 2 aut., 3 aut., 4 aut., 5 aut., 11 aut., 12 aut.); University of Montpellier 1/Montpellier, 34000/France (1 aut., 2 aut., 3 aut., 4 aut., 8 aut., 9 aut., 10 aut., 11 aut., 12 aut.); Faculty of Medicine, Imperial College/London/Royaume-Uni (1 aut.); CHRU Montpellier/Montpellier/France (4 aut., 8 aut., 9 aut., 10 aut.); Department of Psychiatry, University of Geneva/1211/Suisse (5 aut.); Monash Alfred Psychiatry Research Centre, The Alfred & Monash University School of Psychology and Psychiatry/Melbourne/Australie (6 aut.); Centre for Mental Health Research, Australian National University/Canberra/Australie (7 aut.) |
DT : | Publication en série; Niveau analytique |
SO : | Journal of affective disorders; ISSN 0165-0327; Coden JADID7; Royaume-Uni; Da. 2012; Vol. 141; No. 2-3; Pp. 294-299; Bibl. 1/2 p. |
LA : | Anglais |
EA : | Childhood adversity has been observed to engender structural changes in the hippocampus and corpus callosum associated with increased risk for depression in childhood and early adulthood. This study investigated this association in the elderly. Corpus callosum area and hippocampal volume were measured from structural MRI in 427 community dwelling elderly. Information on childhood adversity was obtained in the course of a clinical examination using a questionnaire covering multiple aspects of abuse. Multivariate analyses found a significant increase in corpus callosum area and hippocampal volume in subjects exposed to mental disorder in parents and poverty, respectively. No association was found with childhood sexual and physical abuse. |
CC : | 770D03G01; 770D06B |
FD : | Etat dépressif; Enfant maltraité; Corps calleux; Hippocampe; Imagerie RMN; Victimologie; Personne âgée |
FG : | Homme; Trouble de l'humeur; Encéphale; Système nerveux central; Imagerie médicale |
ED : | Depression; Child abuse; Corpus callosum; Hippocampus; Nuclear magnetic resonance imaging; Victimology; Elderly |
EG : | Human; Mood disorder; Encephalon; Central nervous system; Medical imagery |
SD : | Estado depresivo; Niño maltratado; Cuerpo calloso; Hipocampo; Imaginería RMN; Victimologia; Anciano |
LO : | INIST-18006.354000505387360230 |
ID : | 12-0440546 |
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Francis:12-0440546Le document en format XML
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Depression in elderly persons subject to childhood maltreatment is not modulated by corpus callosum and hippocampal loss</title>
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<series><title level="j" type="main">Journal of affective disorders</title>
<title level="j" type="abbreviated">J. affect. disord.</title>
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<seriesStmt><title level="j" type="main">Journal of affective disorders</title>
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<term>Nuclear magnetic resonance imaging</term>
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<front><div type="abstract" xml:lang="en">Childhood adversity has been observed to engender structural changes in the hippocampus and corpus callosum associated with increased risk for depression in childhood and early adulthood. This study investigated this association in the elderly. Corpus callosum area and hippocampal volume were measured from structural MRI in 427 community dwelling elderly. Information on childhood adversity was obtained in the course of a clinical examination using a questionnaire covering multiple aspects of abuse. Multivariate analyses found a significant increase in corpus callosum area and hippocampal volume in subjects exposed to mental disorder in parents and poverty, respectively. No association was found with childhood sexual and physical abuse.</div>
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<server><NO>FRANCIS 12-0440546 INIST</NO>
<ET>Depression in elderly persons subject to childhood maltreatment is not modulated by corpus callosum and hippocampal loss</ET>
<AU>RITCHIE (Karen); JAUSSENT (Isabelle); PORTET (Florence); COURTET (Philippe); MALAFOSSE (Alain); MALLER (Jerome); MESLIN (Chantal); BONAFE (Alain); LE BARS (Emmanuelle); DE CHAMPFLEUR (Nicolas Menjot); ARTERO (Sylvaine); ANCELIN (Marie-Laure)</AU>
<AF>Inserm, U1061/Montpellier, 34093/France (1 aut., 2 aut., 3 aut., 4 aut., 5 aut., 11 aut., 12 aut.); University of Montpellier 1/Montpellier, 34000/France (1 aut., 2 aut., 3 aut., 4 aut., 8 aut., 9 aut., 10 aut., 11 aut., 12 aut.); Faculty of Medicine, Imperial College/London/Royaume-Uni (1 aut.); CHRU Montpellier/Montpellier/France (4 aut., 8 aut., 9 aut., 10 aut.); Department of Psychiatry, University of Geneva/1211/Suisse (5 aut.); Monash Alfred Psychiatry Research Centre, The Alfred & Monash University School of Psychology and Psychiatry/Melbourne/Australie (6 aut.); Centre for Mental Health Research, Australian National University/Canberra/Australie (7 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Journal of affective disorders; ISSN 0165-0327; Coden JADID7; Royaume-Uni; Da. 2012; Vol. 141; No. 2-3; Pp. 294-299; Bibl. 1/2 p.</SO>
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<EA>Childhood adversity has been observed to engender structural changes in the hippocampus and corpus callosum associated with increased risk for depression in childhood and early adulthood. This study investigated this association in the elderly. Corpus callosum area and hippocampal volume were measured from structural MRI in 427 community dwelling elderly. Information on childhood adversity was obtained in the course of a clinical examination using a questionnaire covering multiple aspects of abuse. Multivariate analyses found a significant increase in corpus callosum area and hippocampal volume in subjects exposed to mental disorder in parents and poverty, respectively. No association was found with childhood sexual and physical abuse.</EA>
<CC>770D03G01; 770D06B</CC>
<FD>Etat dépressif; Enfant maltraité; Corps calleux; Hippocampe; Imagerie RMN; Victimologie; Personne âgée</FD>
<FG>Homme; Trouble de l'humeur; Encéphale; Système nerveux central; Imagerie médicale</FG>
<ED>Depression; Child abuse; Corpus callosum; Hippocampus; Nuclear magnetic resonance imaging; Victimology; Elderly</ED>
<EG>Human; Mood disorder; Encephalon; Central nervous system; Medical imagery</EG>
<SD>Estado depresivo; Niño maltratado; Cuerpo calloso; Hipocampo; Imaginería RMN; Victimologia; Anciano</SD>
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