Haematopoietic SCT in severe autoimmune diseases: updated guidelines of the European Group for Blood and Marrow Transplantation
Identifieur interne : 001274 ( PascalFrancis/Corpus ); précédent : 001273; suivant : 001275Haematopoietic SCT in severe autoimmune diseases: updated guidelines of the European Group for Blood and Marrow Transplantation
Auteurs : J. A. Snowden ; R. Saccardi ; M. Allez ; S. Ardizzone ; R. Arnold ; R. Cervera ; C. Denton ; C. Hawkey ; M. Labopin ; G. Mancardi ; R. Martin ; J. J. Moore ; J. Passweg ; C. Peters ; M. Rabusin ; M. Rovira ; Jm Van Laar ; D. FargeSource :
- Bone marrow transplantation : (Basingstoke) [ 0268-3369 ] ; 2012.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
In 1997, the first consensus guidelines for haematopoietic SCT (HSCT) in autoimmune diseases (ADs) were published, while an international coordinated clinical programme was launched. These guidelines provided broad principles for the field over the following decade and were accompanied by comprehensive data collection in the European Group for Blood and Marrow Transplantation (EBMT) AD Registry. Subsequently, retrospective analyses and prospective phase I/II studies generated evidence to support the feasibility, safety and efficacy of HSCT in several types of severe, treatment-resistant ADs, which became the basis for larger-scale phase II and III studies. In parallel, there has also been an era of immense progress in biological therapy in ADs. The aim of this document is to provide revised and updated guidelines for both the current application and future development of HSCT in ADs in relation to the benefits, risks and health economic considerations of other modern treatments. Patient safety considerations are central to guidance on patient selection and HSCT procedural aspects within appropriately experienced and Joint Accreditation Committee of International Society for Cellular Therapy and EBMT accredited centres. A need for prospective interventional and non-interventional studies, where feasible, along with systematic data reporting, in accordance with EBMT policies and procedures, is emphasized.
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Format Inist (serveur)
NO : | PASCAL 12-0258465 INIST |
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ET : | Haematopoietic SCT in severe autoimmune diseases: updated guidelines of the European Group for Blood and Marrow Transplantation |
AU : | SNOWDEN (J. A.); SACCARDI (R.); ALLEZ (M.); ARDIZZONE (S.); ARNOLD (R.); CERVERA (R.); DENTON (C.); HAWKEY (C.); LABOPIN (M.); MANCARDI (G.); MARTIN (R.); MOORE (J. J.); PASSWEG (J.); PETERS (C.); RABUSIN (M.); ROVIRA (M.); LAAR (Jm Van); FARGE (D.) |
AF : | Department of Haematology, Sheffield Teaching Hospitals NHS Trust/Sheffield/Royaume-Uni (1 aut.); Department of Oncology, University of Sheffield/Sheffield/Royaume-Uni (1 aut.); Department of Haematology, Careggi University Hospital/Firenze/Italie (2 aut.); Service de Gastroentérologie, INSERM U 662, Hôpital St Louis/Paris/France (3 aut.); Department of Gastroenterology, Sacco University Hospital/Milan/Italie (4 aut.); Charite Hospital Berlin/Berlin/Allemagne (5 aut.); Department of Autoimmune Diseases, Hospital Clinic/Barcelona/Espagne (6 aut.); Centre for Rheumatology, Royal Free and University College Medical School/Hampstead, London/Royaume-Uni (7 aut.); Nottingham Digestive Diseases Centre, University of Nottingham/Nottingham/Royaume-Uni (8 aut.); Hôpital Saint Antoine, Service d'Hématologie et Thérapie Cellulaire, AP-HP, UPMC Univ Paris 06/Paris/France (9 aut.); Department of Neuroscience, Ophthalmology and Genetics, University of Genova/Genova/Italie (10 aut.); Institute for Neuroimmunology and Clinical MS Research/Hamburg/Allemagne (11 aut.); St Vincent's Hospital/Sydney, NSW/Australie (12 aut.); Universitaetsspital Basel/Basel/Suisse (13 aut.); BMT Unit, St Anna Children's Hospital/Vienna/Autriche (14 aut.); BMT Unit, Department of Pediatrics, Institute of Maternal and Child Health Burlo Garofolo/Trieste/Italie (15 aut.); SCT Unit, Hematology Department, Hospital Clinic/Barcelona/Espagne (16 aut.); Newcastle University/Newcastle-Upon-Tyne/Royaume-Uni (17 aut.); Department of Internal Medicine, INSERM U 796, Hôpital St Louis/Paris/France (18 aut.) |
DT : | Publication en série; Compte-rendu; Niveau analytique |
SO : | Bone marrow transplantation : (Basingstoke); ISSN 0268-3369; Coden BMTRE9; Royaume-Uni; Da. 2012; Vol. 47; No. 6; Pp. 770-790; Bibl. 204 ref. |
LA : | Anglais |
EA : | In 1997, the first consensus guidelines for haematopoietic SCT (HSCT) in autoimmune diseases (ADs) were published, while an international coordinated clinical programme was launched. These guidelines provided broad principles for the field over the following decade and were accompanied by comprehensive data collection in the European Group for Blood and Marrow Transplantation (EBMT) AD Registry. Subsequently, retrospective analyses and prospective phase I/II studies generated evidence to support the feasibility, safety and efficacy of HSCT in several types of severe, treatment-resistant ADs, which became the basis for larger-scale phase II and III studies. In parallel, there has also been an era of immense progress in biological therapy in ADs. The aim of this document is to provide revised and updated guidelines for both the current application and future development of HSCT in ADs in relation to the benefits, risks and health economic considerations of other modern treatments. Patient safety considerations are central to guidance on patient selection and HSCT procedural aspects within appropriately experienced and Joint Accreditation Committee of International Society for Cellular Therapy and EBMT accredited centres. A need for prospective interventional and non-interventional studies, where feasible, along with systematic data reporting, in accordance with EBMT policies and procedures, is emphasized. |
CC : | 002B27D02 |
FD : | Maladie autoimmune; Directive européenne; Recommandation; Hématologie; Greffe de cellules souches hématopoïétiques; EBMT |
FG : | Immunopathologie |
ED : | Autoimmune disease; European directive; Recommendation; Hematology; Hematopoietic stem cell transplantation; European group for blood and marrow transplantation |
EG : | Immunopathology |
SD : | Enfermedad autoinmune; Directiva europea; Recomendación; Hematología; Injerto de célula primitiva hematopoyética |
LO : | INIST-21176.354000509389020030 |
ID : | 12-0258465 |
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Haematopoietic SCT in severe autoimmune diseases: updated guidelines of the European Group for Blood and Marrow Transplantation</title>
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<author><name sortKey="Allez, M" sort="Allez, M" uniqKey="Allez M" first="M." last="Allez">M. Allez</name>
<affiliation><inist:fA14 i1="04"><s1>Service de Gastroentérologie, INSERM U 662, Hôpital St Louis</s1>
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<author><name sortKey="Hawkey, C" sort="Hawkey, C" uniqKey="Hawkey C" first="C." last="Hawkey">C. Hawkey</name>
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<author><name sortKey="Martin, R" sort="Martin, R" uniqKey="Martin R" first="R." last="Martin">R. Martin</name>
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<author><name sortKey="Moore, J J" sort="Moore, J J" uniqKey="Moore J" first="J. J." last="Moore">J. J. Moore</name>
<affiliation><inist:fA14 i1="13"><s1>St Vincent's Hospital</s1>
<s2>Sydney, NSW</s2>
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<author><name sortKey="Passweg, J" sort="Passweg, J" uniqKey="Passweg J" first="J." last="Passweg">J. Passweg</name>
<affiliation><inist:fA14 i1="14"><s1>Universitaetsspital Basel</s1>
<s2>Basel</s2>
<s3>CHE</s3>
<sZ>13 aut.</sZ>
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<author><name sortKey="Peters, C" sort="Peters, C" uniqKey="Peters C" first="C." last="Peters">C. Peters</name>
<affiliation><inist:fA14 i1="15"><s1>BMT Unit, St Anna Children's Hospital</s1>
<s2>Vienna</s2>
<s3>AUT</s3>
<sZ>14 aut.</sZ>
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<s2>Trieste</s2>
<s3>ITA</s3>
<sZ>15 aut.</sZ>
</inist:fA14>
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<author><name sortKey="Rovira, M" sort="Rovira, M" uniqKey="Rovira M" first="M." last="Rovira">M. Rovira</name>
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<s3>ESP</s3>
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<author><name sortKey="Laar, Jm Van" sort="Laar, Jm Van" uniqKey="Laar J" first="Jm Van" last="Laar">Jm Van Laar</name>
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<s2>Newcastle-Upon-Tyne</s2>
<s3>GBR</s3>
<sZ>17 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Farge, D" sort="Farge, D" uniqKey="Farge D" first="D." last="Farge">D. Farge</name>
<affiliation><inist:fA14 i1="19"><s1>Department of Internal Medicine, INSERM U 796, Hôpital St Louis</s1>
<s2>Paris</s2>
<s3>FRA</s3>
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<term>Directive européenne</term>
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<front><div type="abstract" xml:lang="en">In 1997, the first consensus guidelines for haematopoietic SCT (HSCT) in autoimmune diseases (ADs) were published, while an international coordinated clinical programme was launched. These guidelines provided broad principles for the field over the following decade and were accompanied by comprehensive data collection in the European Group for Blood and Marrow Transplantation (EBMT) AD Registry. Subsequently, retrospective analyses and prospective phase I/II studies generated evidence to support the feasibility, safety and efficacy of HSCT in several types of severe, treatment-resistant ADs, which became the basis for larger-scale phase II and III studies. In parallel, there has also been an era of immense progress in biological therapy in ADs. The aim of this document is to provide revised and updated guidelines for both the current application and future development of HSCT in ADs in relation to the benefits, risks and health economic considerations of other modern treatments. Patient safety considerations are central to guidance on patient selection and HSCT procedural aspects within appropriately experienced and Joint Accreditation Committee of International Society for Cellular Therapy and EBMT accredited centres. A need for prospective interventional and non-interventional studies, where feasible, along with systematic data reporting, in accordance with EBMT policies and procedures, is emphasized.</div>
</front>
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<fA11 i1="01" i2="1"><s1>SNOWDEN (J. A.)</s1>
</fA11>
<fA11 i1="02" i2="1"><s1>SACCARDI (R.)</s1>
</fA11>
<fA11 i1="03" i2="1"><s1>ALLEZ (M.)</s1>
</fA11>
<fA11 i1="04" i2="1"><s1>ARDIZZONE (S.)</s1>
</fA11>
<fA11 i1="05" i2="1"><s1>ARNOLD (R.)</s1>
</fA11>
<fA11 i1="06" i2="1"><s1>CERVERA (R.)</s1>
</fA11>
<fA11 i1="07" i2="1"><s1>DENTON (C.)</s1>
</fA11>
<fA11 i1="08" i2="1"><s1>HAWKEY (C.)</s1>
</fA11>
<fA11 i1="09" i2="1"><s1>LABOPIN (M.)</s1>
</fA11>
<fA11 i1="10" i2="1"><s1>MANCARDI (G.)</s1>
</fA11>
<fA11 i1="11" i2="1"><s1>MARTIN (R.)</s1>
</fA11>
<fA11 i1="12" i2="1"><s1>MOORE (J. J.)</s1>
</fA11>
<fA11 i1="13" i2="1"><s1>PASSWEG (J.)</s1>
</fA11>
<fA11 i1="14" i2="1"><s1>PETERS (C.)</s1>
</fA11>
<fA11 i1="15" i2="1"><s1>RABUSIN (M.)</s1>
</fA11>
<fA11 i1="16" i2="1"><s1>ROVIRA (M.)</s1>
</fA11>
<fA11 i1="17" i2="1"><s1>LAAR (Jm Van)</s1>
</fA11>
<fA11 i1="18" i2="1"><s1>FARGE (D.)</s1>
</fA11>
<fA14 i1="01"><s1>Department of Haematology, Sheffield Teaching Hospitals NHS Trust</s1>
<s2>Sheffield</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
</fA14>
<fA14 i1="02"><s1>Department of Oncology, University of Sheffield</s1>
<s2>Sheffield</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
</fA14>
<fA14 i1="03"><s1>Department of Haematology, Careggi University Hospital</s1>
<s2>Firenze</s2>
<s3>ITA</s3>
<sZ>2 aut.</sZ>
</fA14>
<fA14 i1="04"><s1>Service de Gastroentérologie, INSERM U 662, Hôpital St Louis</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>3 aut.</sZ>
</fA14>
<fA14 i1="05"><s1>Department of Gastroenterology, Sacco University Hospital</s1>
<s2>Milan</s2>
<s3>ITA</s3>
<sZ>4 aut.</sZ>
</fA14>
<fA14 i1="06"><s1>Charite Hospital Berlin</s1>
<s2>Berlin</s2>
<s3>DEU</s3>
<sZ>5 aut.</sZ>
</fA14>
<fA14 i1="07"><s1>Department of Autoimmune Diseases, Hospital Clinic</s1>
<s2>Barcelona</s2>
<s3>ESP</s3>
<sZ>6 aut.</sZ>
</fA14>
<fA14 i1="08"><s1>Centre for Rheumatology, Royal Free and University College Medical School</s1>
<s2>Hampstead, London</s2>
<s3>GBR</s3>
<sZ>7 aut.</sZ>
</fA14>
<fA14 i1="09"><s1>Nottingham Digestive Diseases Centre, University of Nottingham</s1>
<s2>Nottingham</s2>
<s3>GBR</s3>
<sZ>8 aut.</sZ>
</fA14>
<fA14 i1="10"><s1>Hôpital Saint Antoine, Service d'Hématologie et Thérapie Cellulaire, AP-HP, UPMC Univ Paris 06</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>9 aut.</sZ>
</fA14>
<fA14 i1="11"><s1>Department of Neuroscience, Ophthalmology and Genetics, University of Genova</s1>
<s2>Genova</s2>
<s3>ITA</s3>
<sZ>10 aut.</sZ>
</fA14>
<fA14 i1="12"><s1>Institute for Neuroimmunology and Clinical MS Research</s1>
<s2>Hamburg</s2>
<s3>DEU</s3>
<sZ>11 aut.</sZ>
</fA14>
<fA14 i1="13"><s1>St Vincent's Hospital</s1>
<s2>Sydney, NSW</s2>
<s3>AUS</s3>
<sZ>12 aut.</sZ>
</fA14>
<fA14 i1="14"><s1>Universitaetsspital Basel</s1>
<s2>Basel</s2>
<s3>CHE</s3>
<sZ>13 aut.</sZ>
</fA14>
<fA14 i1="15"><s1>BMT Unit, St Anna Children's Hospital</s1>
<s2>Vienna</s2>
<s3>AUT</s3>
<sZ>14 aut.</sZ>
</fA14>
<fA14 i1="16"><s1>BMT Unit, Department of Pediatrics, Institute of Maternal and Child Health Burlo Garofolo</s1>
<s2>Trieste</s2>
<s3>ITA</s3>
<sZ>15 aut.</sZ>
</fA14>
<fA14 i1="17"><s1>SCT Unit, Hematology Department, Hospital Clinic</s1>
<s2>Barcelona</s2>
<s3>ESP</s3>
<sZ>16 aut.</sZ>
</fA14>
<fA14 i1="18"><s1>Newcastle University</s1>
<s2>Newcastle-Upon-Tyne</s2>
<s3>GBR</s3>
<sZ>17 aut.</sZ>
</fA14>
<fA14 i1="19"><s1>Department of Internal Medicine, INSERM U 796, Hôpital St Louis</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>18 aut.</sZ>
</fA14>
<fA17 i1="01" i2="1"><s1>EBMT Autoimmune Disease Working Party (ADWP) and Paediatric Diseases Working Party (PDWP)</s1>
<s3>INC</s3>
</fA17>
<fA20><s1>770-790</s1>
</fA20>
<fA21><s1>2012</s1>
</fA21>
<fA23 i1="01"><s0>ENG</s0>
</fA23>
<fA43 i1="01"><s1>INIST</s1>
<s2>21176</s2>
<s5>354000509389020030</s5>
</fA43>
<fA44><s0>0000</s0>
<s1>© 2012 INIST-CNRS. All rights reserved.</s1>
</fA44>
<fA45><s0>204 ref.</s0>
</fA45>
<fA47 i1="01" i2="1"><s0>12-0258465</s0>
</fA47>
<fA60><s1>P</s1>
<s3>C</s3>
</fA60>
<fA61><s0>A</s0>
</fA61>
<fA64 i1="01" i2="1"><s0>Bone marrow transplantation : (Basingstoke)</s0>
</fA64>
<fA66 i1="01"><s0>GBR</s0>
</fA66>
<fC01 i1="01" l="ENG"><s0>In 1997, the first consensus guidelines for haematopoietic SCT (HSCT) in autoimmune diseases (ADs) were published, while an international coordinated clinical programme was launched. These guidelines provided broad principles for the field over the following decade and were accompanied by comprehensive data collection in the European Group for Blood and Marrow Transplantation (EBMT) AD Registry. Subsequently, retrospective analyses and prospective phase I/II studies generated evidence to support the feasibility, safety and efficacy of HSCT in several types of severe, treatment-resistant ADs, which became the basis for larger-scale phase II and III studies. In parallel, there has also been an era of immense progress in biological therapy in ADs. The aim of this document is to provide revised and updated guidelines for both the current application and future development of HSCT in ADs in relation to the benefits, risks and health economic considerations of other modern treatments. Patient safety considerations are central to guidance on patient selection and HSCT procedural aspects within appropriately experienced and Joint Accreditation Committee of International Society for Cellular Therapy and EBMT accredited centres. A need for prospective interventional and non-interventional studies, where feasible, along with systematic data reporting, in accordance with EBMT policies and procedures, is emphasized.</s0>
</fC01>
<fC02 i1="01" i2="X"><s0>002B27D02</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE"><s0>Maladie autoimmune</s0>
<s5>02</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG"><s0>Autoimmune disease</s0>
<s5>02</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>Enfermedad autoinmune</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE"><s0>Directive européenne</s0>
<s5>03</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>European directive</s0>
<s5>03</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA"><s0>Directiva europea</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Recommandation</s0>
<s5>05</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Recommendation</s0>
<s5>05</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Recomendación</s0>
<s5>05</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Hématologie</s0>
<s5>06</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Hematology</s0>
<s5>06</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Hematología</s0>
<s5>06</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE"><s0>Greffe de cellules souches hématopoïétiques</s0>
<s4>CD</s4>
<s5>96</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG"><s0>Hematopoietic stem cell transplantation</s0>
<s4>CD</s4>
<s5>96</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Injerto de célula primitiva hematopoyética</s0>
<s4>CD</s4>
<s5>96</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE"><s0>EBMT</s0>
<s4>CD</s4>
<s5>97</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG"><s0>European group for blood and marrow transplantation</s0>
<s4>CD</s4>
<s5>97</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Immunopathologie</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Immunopathology</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Inmunopatología</s0>
<s5>37</s5>
</fC07>
<fN21><s1>198</s1>
</fN21>
<fN44 i1="01"><s1>OTO</s1>
</fN44>
<fN82><s1>OTO</s1>
</fN82>
</pA>
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<server><NO>PASCAL 12-0258465 INIST</NO>
<ET>Haematopoietic SCT in severe autoimmune diseases: updated guidelines of the European Group for Blood and Marrow Transplantation</ET>
<AU>SNOWDEN (J. A.); SACCARDI (R.); ALLEZ (M.); ARDIZZONE (S.); ARNOLD (R.); CERVERA (R.); DENTON (C.); HAWKEY (C.); LABOPIN (M.); MANCARDI (G.); MARTIN (R.); MOORE (J. J.); PASSWEG (J.); PETERS (C.); RABUSIN (M.); ROVIRA (M.); LAAR (Jm Van); FARGE (D.)</AU>
<AF>Department of Haematology, Sheffield Teaching Hospitals NHS Trust/Sheffield/Royaume-Uni (1 aut.); Department of Oncology, University of Sheffield/Sheffield/Royaume-Uni (1 aut.); Department of Haematology, Careggi University Hospital/Firenze/Italie (2 aut.); Service de Gastroentérologie, INSERM U 662, Hôpital St Louis/Paris/France (3 aut.); Department of Gastroenterology, Sacco University Hospital/Milan/Italie (4 aut.); Charite Hospital Berlin/Berlin/Allemagne (5 aut.); Department of Autoimmune Diseases, Hospital Clinic/Barcelona/Espagne (6 aut.); Centre for Rheumatology, Royal Free and University College Medical School/Hampstead, London/Royaume-Uni (7 aut.); Nottingham Digestive Diseases Centre, University of Nottingham/Nottingham/Royaume-Uni (8 aut.); Hôpital Saint Antoine, Service d'Hématologie et Thérapie Cellulaire, AP-HP, UPMC Univ Paris 06/Paris/France (9 aut.); Department of Neuroscience, Ophthalmology and Genetics, University of Genova/Genova/Italie (10 aut.); Institute for Neuroimmunology and Clinical MS Research/Hamburg/Allemagne (11 aut.); St Vincent's Hospital/Sydney, NSW/Australie (12 aut.); Universitaetsspital Basel/Basel/Suisse (13 aut.); BMT Unit, St Anna Children's Hospital/Vienna/Autriche (14 aut.); BMT Unit, Department of Pediatrics, Institute of Maternal and Child Health Burlo Garofolo/Trieste/Italie (15 aut.); SCT Unit, Hematology Department, Hospital Clinic/Barcelona/Espagne (16 aut.); Newcastle University/Newcastle-Upon-Tyne/Royaume-Uni (17 aut.); Department of Internal Medicine, INSERM U 796, Hôpital St Louis/Paris/France (18 aut.)</AF>
<DT>Publication en série; Compte-rendu; Niveau analytique</DT>
<SO>Bone marrow transplantation : (Basingstoke); ISSN 0268-3369; Coden BMTRE9; Royaume-Uni; Da. 2012; Vol. 47; No. 6; Pp. 770-790; Bibl. 204 ref.</SO>
<LA>Anglais</LA>
<EA>In 1997, the first consensus guidelines for haematopoietic SCT (HSCT) in autoimmune diseases (ADs) were published, while an international coordinated clinical programme was launched. These guidelines provided broad principles for the field over the following decade and were accompanied by comprehensive data collection in the European Group for Blood and Marrow Transplantation (EBMT) AD Registry. Subsequently, retrospective analyses and prospective phase I/II studies generated evidence to support the feasibility, safety and efficacy of HSCT in several types of severe, treatment-resistant ADs, which became the basis for larger-scale phase II and III studies. In parallel, there has also been an era of immense progress in biological therapy in ADs. The aim of this document is to provide revised and updated guidelines for both the current application and future development of HSCT in ADs in relation to the benefits, risks and health economic considerations of other modern treatments. Patient safety considerations are central to guidance on patient selection and HSCT procedural aspects within appropriately experienced and Joint Accreditation Committee of International Society for Cellular Therapy and EBMT accredited centres. A need for prospective interventional and non-interventional studies, where feasible, along with systematic data reporting, in accordance with EBMT policies and procedures, is emphasized.</EA>
<CC>002B27D02</CC>
<FD>Maladie autoimmune; Directive européenne; Recommandation; Hématologie; Greffe de cellules souches hématopoïétiques; EBMT</FD>
<FG>Immunopathologie</FG>
<ED>Autoimmune disease; European directive; Recommendation; Hematology; Hematopoietic stem cell transplantation; European group for blood and marrow transplantation</ED>
<EG>Immunopathology</EG>
<SD>Enfermedad autoinmune; Directiva europea; Recomendación; Hematología; Injerto de célula primitiva hematopoyética</SD>
<LO>INIST-21176.354000509389020030</LO>
<ID>12-0258465</ID>
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