Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines-2016 revision.
Identifieur interne : 004963 ( Ncbi/Merge ); précédent : 004962; suivant : 004964Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines-2016 revision.
Auteurs : Jan L. Bro Ek [Canada] ; Jean Bousquet [France] ; Ioana Agache [Roumanie] ; Arnav Agarwal [Canada] ; Claus Bachert [Belgique] ; Sinthia Bosnic-Anticevich [Australie] ; Romina Brignardello-Petersen [Canada] ; G Walter Canonica [Italie] ; Thomas Casale [États-Unis] ; Niels H. Chavannes [Pays-Bas] ; Jaime Correia De Sousa [Portugal] ; Alvaro A. Cruz [Brésil] ; Carlos A. Cuello-Garcia [Canada] ; Pascal Demoly [France] ; Mark Dykewicz ; Itziar Etxeandia-Ikobaltzeta [Espagne] ; Ivan D. Florez [Colombie] ; Wytske Fokkens [Pays-Bas] ; Joao Fonseca [Portugal] ; Peter W. Hellings [Pays-Bas] ; Ludger Klimek [Allemagne] ; Sergio Kowalski [Canada] ; Piotr Kuna [Pologne] ; Kaja-Triin Laisaar [Estonie] ; Désirée E. Larenas-Linnemann [Mexique] ; Karin C. L Drup Carlsen [Norvège] ; Peter J. Manning [Irlande (pays)] ; Eli Meltzer ; Joaquim Mullol [Espagne] ; Antonella Muraro [Italie] ; Robyn O'Hehir [Australie] ; Ken Ohta [Japon] ; Petr Panzner [République tchèque] ; Nikolaos Papadopoulos [Royaume-Uni] ; Hae-Sim Park [Corée du Sud] ; Gianni Passalacqua [Italie] ; Ruby Pawankar [Japon] ; David Price [Royaume-Uni] ; John J. Riva [Canada] ; Yetiani Roldán [Canada] ; Dermot Ryan [Royaume-Uni] ; Behnam Sadeghirad [Iran] ; Boleslaw Samolinski [Pologne] ; Peter Schmid-Grendelmeier [Suisse] ; Aziz Sheikh [Royaume-Uni] ; Alkis Togias ; Antonio Valero [Espagne] ; Arunas Valiulis [Belgique] ; Erkka Valovirta [Finlande] ; Matthew Ventresca [Canada] ; Dana Wallace ; Susan Waserman [Canada] ; Magnus Wickman [Suède] ; Wojtek Wiercioch [Canada] ; Juan José Yepes-Nu Ez [Colombie] ; Luo Zhang [République populaire de Chine] ; Yuan Zhang [Canada] ; Mihaela Zidarn [Slovénie] ; Torsten Zuberbier [Allemagne] ; Holger J. Schünemann [Canada]Source :
- The Journal of allergy and clinical immunology [ 1097-6825 ] ; 2017.
Descripteurs français
- KwdFr :
- MESH :
- traitement médicamenteux : Rhinite allergique.
- usage thérapeutique : Antiallergiques, Antihistaminiques des récepteurs H1.
- épidémiologie : Rhinite allergique.
- Animaux, Asthme, Enfant, Humains, Pratique factuelle, Prise de décision clinique, Qualité de vie.
English descriptors
- KwdEn :
- MESH :
- chemical , therapeutic use : Anti-Allergic Agents, Histamine H1 Antagonists.
- drug therapy : Rhinitis, Allergic.
- epidemiology : Rhinitis, Allergic.
- prevention & control : Asthma.
- Animals, Child, Clinical Decision-Making, Evidence-Based Practice, Humans, Quality of Life.
Abstract
Allergic rhinitis (AR) affects 10% to 40% of the population. It reduces quality of life and school and work performance and is a frequent reason for office visits in general practice. Medical costs are large, but avoidable costs associated with lost work productivity are even larger than those incurred by asthma. New evidence has accumulated since the last revision of the Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines in 2010, prompting its update.
DOI: 10.1016/j.jaci.2017.03.050
PubMed: 28602936
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School of Medicine, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; School of Medicine, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Bachert, Claus" sort="Bachert, Claus" uniqKey="Bachert C" first="Claus" last="Bachert">Claus Bachert</name><affiliation wicri:level="1"><nlm:affiliation>Upper Airways Research Laboratory, Ghent University Hospital, Ghent, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Upper Airways Research Laboratory, Ghent University Hospital, Ghent</wicri:regionArea><wicri:noRegion>Ghent</wicri:noRegion></affiliation></author><author><name sortKey="Bosnic Anticevich, Sinthia" sort="Bosnic Anticevich, Sinthia" uniqKey="Bosnic Anticevich S" first="Sinthia" last="Bosnic-Anticevich">Sinthia Bosnic-Anticevich</name><affiliation wicri:level="4"><nlm:affiliation>Woolcock Institute, University of Sydney, Sydney, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Woolcock Institute, University of Sydney, Sydney</wicri:regionArea><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region><settlement type="city">Sydney</settlement></placeName><orgName type="university">Université de Sydney</orgName></affiliation></author><author><name sortKey="Brignardello Petersen, Romina" sort="Brignardello Petersen, Romina" uniqKey="Brignardello Petersen R" first="Romina" last="Brignardello-Petersen">Romina Brignardello-Petersen</name><affiliation wicri:level="4"><nlm:affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Canonica, G Walter" sort="Canonica, G Walter" uniqKey="Canonica G" first="G Walter" last="Canonica">G Walter Canonica</name><affiliation wicri:level="3"><nlm:affiliation>Asthma & Allergy Clinic, Humanitas University, Rozzano, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Asthma & Allergy Clinic, Humanitas University, Rozzano, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Casale, Thomas" sort="Casale, Thomas" uniqKey="Casale T" first="Thomas" last="Casale">Thomas Casale</name><affiliation wicri:level="4"><nlm:affiliation>Division of Allergy and Immunology, University of South Florida, Tampa, Fla.</nlm:affiliation><orgName type="university">Université de Floride du Sud</orgName><country>États-Unis</country><placeName><settlement type="city">Tampa</settlement><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Chavannes, Niels H" sort="Chavannes, Niels H" uniqKey="Chavannes N" first="Niels H" last="Chavannes">Niels H. Chavannes</name><affiliation wicri:level="3"><nlm:affiliation>Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Public Health and Primary Care, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Correia De Sousa, Jaime" sort="Correia De Sousa, Jaime" uniqKey="Correia De Sousa J" first="Jaime" last="Correia De Sousa">Jaime Correia De Sousa</name><affiliation wicri:level="4"><nlm:affiliation>Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, and ICVS/3B's-PT Government Associate Laboratory, Braga/Guimarães, Portugal.</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, and ICVS/3B's-PT Government Associate Laboratory, Braga/Guimarães</wicri:regionArea><orgName type="university">Université du Minho</orgName><placeName><settlement type="city">Braga</settlement><region>Région Nord (Portugal)</region></placeName></affiliation></author><author><name sortKey="Cruz, Alvaro A" sort="Cruz, Alvaro A" uniqKey="Cruz A" first="Alvaro A" last="Cruz">Alvaro A. Cruz</name><affiliation wicri:level="1"><nlm:affiliation>ProAR-Center of Excellence for Asthma, Federal University of Bahia, Salvador, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>ProAR-Center of Excellence for Asthma, Federal University of Bahia, Salvador</wicri:regionArea><wicri:noRegion>Salvador</wicri:noRegion></affiliation></author><author><name sortKey="Cuello Garcia, Carlos A" sort="Cuello Garcia, Carlos A" uniqKey="Cuello Garcia C" first="Carlos A" last="Cuello-Garcia">Carlos A. Cuello-Garcia</name><affiliation wicri:level="4"><nlm:affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Demoly, Pascal" sort="Demoly, Pascal" uniqKey="Demoly P" first="Pascal" last="Demoly">Pascal Demoly</name><affiliation wicri:level="3"><nlm:affiliation>University Hospital of Montpellier, Montpellier, and Sorbonne Universités, UPMC Paris 06, UMR-S 1136, IPLESP, Equipe EPAR, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University Hospital of Montpellier, Montpellier, and Sorbonne Universités, UPMC Paris 06, UMR-S 1136, IPLESP, Equipe EPAR, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Dykewicz, Mark" sort="Dykewicz, Mark" uniqKey="Dykewicz M" first="Mark" last="Dykewicz">Mark Dykewicz</name><affiliation><nlm:affiliation>Section of Allergy and Immunology, Department of Internal Medicine, Saint Louis University School of Medicine, St Louis, Mo.</nlm:affiliation><wicri:noCountry code="subField">Mo</wicri:noCountry></affiliation></author><author><name sortKey="Etxeandia Ikobaltzeta, Itziar" sort="Etxeandia Ikobaltzeta, Itziar" uniqKey="Etxeandia Ikobaltzeta I" first="Itziar" last="Etxeandia-Ikobaltzeta">Itziar Etxeandia-Ikobaltzeta</name><affiliation wicri:level="4"><nlm:affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; Dirección de Investigación e Innovación Sanitaria, Departamento de Salud, Gobierno Vasco-Eusko Jaurlaritza, Vitoria-Gasteiz, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; Dirección de Investigación e Innovación Sanitaria, Departamento de Salud, Gobierno Vasco-Eusko Jaurlaritza, Vitoria-Gasteiz</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Florez, Ivan D" sort="Florez, Ivan D" uniqKey="Florez I" first="Ivan D" last="Florez">Ivan D. Florez</name><affiliation wicri:level="4"><nlm:affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; Department of Pediatrics, University of Antioquia, Medellin, Colombia.</nlm:affiliation><country xml:lang="fr">Colombie</country><wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; Department of Pediatrics, University of Antioquia, Medellin</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Fokkens, Wytske" sort="Fokkens, Wytske" uniqKey="Fokkens W" first="Wytske" last="Fokkens">Wytske Fokkens</name><affiliation wicri:level="3"><nlm:affiliation>Department of Otorhinolaryngology, Academic Medical Centre, Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Otorhinolaryngology, Academic Medical Centre, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Fonseca, Joao" sort="Fonseca, Joao" uniqKey="Fonseca J" first="Joao" last="Fonseca">Joao Fonseca</name><affiliation wicri:level="1"><nlm:affiliation>CINTESIS-Center for Health Technology and Services Research, Faculdade de Medicina, Universidade do Porto & Allergy, CUF Porto Hospital and Instituto, Porto, Portugal.</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>CINTESIS-Center for Health Technology and Services Research, Faculdade de Medicina, Universidade do Porto & Allergy, CUF Porto Hospital and Instituto, Porto</wicri:regionArea><wicri:noRegion>Porto</wicri:noRegion></affiliation></author><author><name sortKey="Hellings, Peter W" sort="Hellings, Peter W" uniqKey="Hellings P" first="Peter W" last="Hellings">Peter W. Hellings</name><affiliation wicri:level="3"><nlm:affiliation>Department of Otorhinolaryngology, University Hospitals Leuven, and the Department of Otorhinolaryngology, Academic Medical Center (AMC), Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Otorhinolaryngology, University Hospitals Leuven, and the Department of Otorhinolaryngology, Academic Medical Center (AMC), Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Klimek, Ludger" sort="Klimek, Ludger" uniqKey="Klimek L" first="Ludger" last="Klimek">Ludger Klimek</name><affiliation wicri:level="1"><nlm:affiliation>Center of Rhinology and Allergology, Wiesbaden, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Center of Rhinology and Allergology, Wiesbaden</wicri:regionArea><wicri:noRegion>Wiesbaden</wicri:noRegion><wicri:noRegion>Wiesbaden</wicri:noRegion><wicri:noRegion>Wiesbaden</wicri:noRegion></affiliation></author><author><name sortKey="Kowalski, Sergio" sort="Kowalski, Sergio" uniqKey="Kowalski S" first="Sergio" last="Kowalski">Sergio Kowalski</name><affiliation wicri:level="4"><nlm:affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Kuna, Piotr" sort="Kuna, Piotr" uniqKey="Kuna P" first="Piotr" last="Kuna">Piotr Kuna</name><affiliation wicri:level="1"><nlm:affiliation>Division of Internal Medicine Asthma and Allergy, Faculty of Medicine, Medical University of Lodz, Lodz, Poland.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Division of Internal Medicine Asthma and Allergy, Faculty of Medicine, Medical University of Lodz, Lodz</wicri:regionArea><wicri:noRegion>Lodz</wicri:noRegion></affiliation></author><author><name sortKey="Laisaar, Kaja Triin" sort="Laisaar, Kaja Triin" uniqKey="Laisaar K" first="Kaja-Triin" last="Laisaar">Kaja-Triin Laisaar</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Family Medicine and Public Health, University of Tartu, Tartu, Estonia.</nlm:affiliation><country xml:lang="fr">Estonie</country><wicri:regionArea>Institute of Family Medicine and Public Health, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation></author><author><name sortKey="Larenas Linnemann, Desiree E" sort="Larenas Linnemann, Desiree E" uniqKey="Larenas Linnemann D" first="Désirée E" last="Larenas-Linnemann">Désirée E. Larenas-Linnemann</name><affiliation wicri:level="1"><nlm:affiliation>Hospital Médica Sur, Mexico City, Mexico.</nlm:affiliation><country xml:lang="fr">Mexique</country><wicri:regionArea>Hospital Médica Sur, Mexico City</wicri:regionArea><wicri:noRegion>Mexico City</wicri:noRegion></affiliation></author><author><name sortKey="L Drup Carlsen, Karin C" sort="L Drup Carlsen, Karin C" uniqKey="L Drup Carlsen K" first="Karin C" last="L Drup Carlsen">Karin C. L Drup Carlsen</name><affiliation wicri:level="3"><nlm:affiliation>Department of Paediatrics, Oslo University Hospital, University of Oslo, Oslo, Norway.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Paediatrics, Oslo University Hospital, University of Oslo, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation></author><author><name sortKey="Manning, Peter J" sort="Manning, Peter J" uniqKey="Manning P" first="Peter J" last="Manning">Peter J. Manning</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, Royal College of Surgeons in Ireland Medical School, Dublin, Ireland.</nlm:affiliation><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Department of Medicine, Royal College of Surgeons in Ireland Medical School, Dublin</wicri:regionArea><wicri:noRegion>Dublin</wicri:noRegion></affiliation></author><author><name sortKey="Meltzer, Eli" sort="Meltzer, Eli" uniqKey="Meltzer E" first="Eli" last="Meltzer">Eli Meltzer</name><affiliation><nlm:affiliation>Department of Pediatrics, Division of Allergy & Immunology, University of California, San Diego, Calif.</nlm:affiliation><wicri:noCountry code="subField">Calif</wicri:noCountry></affiliation></author><author><name sortKey="Mullol, Joaquim" sort="Mullol, Joaquim" uniqKey="Mullol J" first="Joaquim" last="Mullol">Joaquim Mullol</name><affiliation wicri:level="3"><nlm:affiliation>Unitat de Rinologia i Clínica de l'Olfacte, Servei d'ORL, Hospital Clínic, Clinical & Experimental Respiratory Immunoallergy, IDIBAPS, Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Unitat de Rinologia i Clínica de l'Olfacte, Servei d'ORL, Hospital Clínic, Clinical & Experimental Respiratory Immunoallergy, IDIBAPS, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Muraro, Antonella" sort="Muraro, Antonella" uniqKey="Muraro A" first="Antonella" last="Muraro">Antonella Muraro</name><affiliation wicri:level="1"><nlm:affiliation>Department of Women and Child Health & Food Allergy Referral Centre Veneto Region, University of Padua, Padua, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Women and Child Health & Food Allergy Referral Centre Veneto Region, University of Padua, Padua</wicri:regionArea><wicri:noRegion>Padua</wicri:noRegion></affiliation></author><author><name sortKey="O Hehir, Robyn" sort="O Hehir, Robyn" uniqKey="O Hehir R" first="Robyn" last="O'Hehir">Robyn O'Hehir</name><affiliation wicri:level="3"><nlm:affiliation>Alfred Hospital and Monash University, Melbourne, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Alfred Hospital and Monash University, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Ohta, Ken" sort="Ohta, Ken" uniqKey="Ohta K" first="Ken" last="Ohta">Ken Ohta</name><affiliation wicri:level="3"><nlm:affiliation>National Hospital Organization Tokyo National Hospital, Kiyose-city, Tokyo, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>National Hospital Organization Tokyo National Hospital, Kiyose-city, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region></placeName></affiliation></author><author><name sortKey="Panzner, Petr" sort="Panzner, Petr" uniqKey="Panzner P" first="Petr" last="Panzner">Petr Panzner</name><affiliation wicri:level="3"><nlm:affiliation>Department of Immunology and Allergology, Faculty of Medicine in Pilsen, Charles University in Prague, Prague, Czech Republic.</nlm:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Department of Immunology and Allergology, Faculty of Medicine in Pilsen, Charles University in Prague, Prague</wicri:regionArea><placeName><settlement type="city">Prague</settlement><region type="région" nuts="2">Bohême centrale</region></placeName></affiliation></author><author><name sortKey="Papadopoulos, Nikolaos" sort="Papadopoulos, Nikolaos" uniqKey="Papadopoulos N" first="Nikolaos" last="Papadopoulos">Nikolaos Papadopoulos</name><affiliation wicri:level="3"><nlm:affiliation>Allergy Department, 2nd Pediatric Clinic, University of Athens, Athens, Greece; Division of Infection, Immunity & Respiratory Medicine, University of Manchester, Manchester, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Allergy Department, 2nd Pediatric Clinic, University of Athens, Athens, Greece; Division of Infection, Immunity & Respiratory Medicine, University of Manchester, Manchester</wicri:regionArea><placeName><settlement type="city">Manchester</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Manchester</region></placeName></affiliation></author><author><name sortKey="Park, Hae Sim" sort="Park, Hae Sim" uniqKey="Park H" first="Hae-Sim" last="Park">Hae-Sim Park</name><affiliation wicri:level="1"><nlm:affiliation>Department of Allergy and Rheumatology, Ajou University School of Medicine, Suwon, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Allergy and Rheumatology, Ajou University School of Medicine, Suwon</wicri:regionArea><wicri:noRegion>Suwon</wicri:noRegion></affiliation></author><author><name sortKey="Passalacqua, Gianni" sort="Passalacqua, Gianni" uniqKey="Passalacqua G" first="Gianni" last="Passalacqua">Gianni Passalacqua</name><affiliation wicri:level="1"><nlm:affiliation>Allergy and Respiratory Diseases, IRCCS San Martino, IST, University of Genoa, Genoa, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Allergy and Respiratory Diseases, IRCCS San Martino, IST, University of Genoa, Genoa</wicri:regionArea><wicri:noRegion>Genoa</wicri:noRegion></affiliation></author><author><name sortKey="Pawankar, Ruby" sort="Pawankar, Ruby" uniqKey="Pawankar R" first="Ruby" last="Pawankar">Ruby Pawankar</name><affiliation wicri:level="3"><nlm:affiliation>Department of Pediatrics, Nippon Medical School, Tokyo, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Pediatrics, Nippon Medical School, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region></placeName></affiliation></author><author><name sortKey="Price, David" sort="Price, David" uniqKey="Price D" first="David" last="Price">David Price</name><affiliation wicri:level="1"><nlm:affiliation>University of Aberdeen, Aberdeen, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>University of Aberdeen, Aberdeen</wicri:regionArea><wicri:noRegion>Aberdeen</wicri:noRegion></affiliation></author><author><name sortKey="Riva, John J" sort="Riva, John J" uniqKey="Riva J" first="John J" last="Riva">John J. Riva</name><affiliation wicri:level="4"><nlm:affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; Department of Family Medicine, McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; Department of Family Medicine, McMaster University, Hamilton, Ontario</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Roldan, Yetiani" sort="Roldan, Yetiani" uniqKey="Roldan Y" first="Yetiani" last="Roldán">Yetiani Roldán</name><affiliation wicri:level="4"><nlm:affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Ryan, Dermot" sort="Ryan, Dermot" uniqKey="Ryan D" first="Dermot" last="Ryan">Dermot Ryan</name><affiliation wicri:level="4"><nlm:affiliation>Allergy and Respiratory Research Group, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Allergy and Respiratory Research Group, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Sadeghirad, Behnam" sort="Sadeghirad, Behnam" uniqKey="Sadeghirad B" first="Behnam" last="Sadeghirad">Behnam Sadeghirad</name><affiliation wicri:level="1"><nlm:affiliation>HIV/STI Surveillance Research Center, and World Health Organization Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran.</nlm:affiliation><country xml:lang="fr">Iran</country><wicri:regionArea>HIV/STI Surveillance Research Center, and World Health Organization Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman</wicri:regionArea><wicri:noRegion>Kerman</wicri:noRegion></affiliation></author><author><name sortKey="Samolinski, Boleslaw" sort="Samolinski, Boleslaw" uniqKey="Samolinski B" first="Boleslaw" last="Samolinski">Boleslaw Samolinski</name><affiliation wicri:level="1"><nlm:affiliation>Department of Prevention of Environmental Hazards and Allergology, Medical University of Warsaw, Warsaw, Poland.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Prevention of Environmental Hazards and Allergology, Medical University of Warsaw, Warsaw</wicri:regionArea><wicri:noRegion>Warsaw</wicri:noRegion></affiliation></author><author><name sortKey="Schmid Grendelmeier, Peter" sort="Schmid Grendelmeier, Peter" uniqKey="Schmid Grendelmeier P" first="Peter" last="Schmid-Grendelmeier">Peter Schmid-Grendelmeier</name><affiliation wicri:level="1"><nlm:affiliation>Allergy Unit, Department of Dermatology, University Hospital of Zürich and Christine Kühne Center for Allergy Research and Education CK-CARE, Davos, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Allergy Unit, Department of Dermatology, University Hospital of Zürich and Christine Kühne Center for Allergy Research and Education CK-CARE, Davos</wicri:regionArea><wicri:noRegion>Davos</wicri:noRegion></affiliation></author><author><name sortKey="Sheikh, Aziz" sort="Sheikh, Aziz" uniqKey="Sheikh A" first="Aziz" last="Sheikh">Aziz Sheikh</name><affiliation wicri:level="4"><nlm:affiliation>Asthma UK Centre for Applied Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Asthma UK Centre for Applied Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Togias, Alkis" sort="Togias, Alkis" uniqKey="Togias A" first="Alkis" last="Togias">Alkis Togias</name><affiliation><nlm:affiliation>Asthma and Inflammation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.</nlm:affiliation><wicri:noCountry code="subField">Md</wicri:noCountry></affiliation></author><author><name sortKey="Valero, Antonio" sort="Valero, Antonio" uniqKey="Valero A" first="Antonio" last="Valero">Antonio Valero</name><affiliation wicri:level="3"><nlm:affiliation>Department of Pneumology and Allergy, Immunoallèrgia Respiratòria Clínica I Experimental (IDIBAPS), Centro de Investigaciones Biomédicas en Red de Enfermedades Respiratorias (CIBERES), Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Pneumology and Allergy, Immunoallèrgia Respiratòria Clínica I Experimental (IDIBAPS), Centro de Investigaciones Biomédicas en Red de Enfermedades Respiratorias (CIBERES), Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Valiulis, Arunas" sort="Valiulis, Arunas" uniqKey="Valiulis A" first="Arunas" last="Valiulis">Arunas Valiulis</name><affiliation wicri:level="3"><nlm:affiliation>Vilnius University Clinic of Children's Diseases and Public Health Institute, Vilnius, and the European Academy of Paediatrics (EAP/UEMS-SP), Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Vilnius University Clinic of Children's Diseases and Public Health Institute, Vilnius, and the European Academy of Paediatrics (EAP/UEMS-SP), Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation></author><author><name sortKey="Valovirta, Erkka" sort="Valovirta, Erkka" uniqKey="Valovirta E" first="Erkka" last="Valovirta">Erkka Valovirta</name><affiliation wicri:level="3"><nlm:affiliation>Department of Lung Diseases and Clinical Immunology, University of Turku and Allergy Clinic Terveystalo Turku, Turku, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Lung Diseases and Clinical Immunology, University of Turku and Allergy Clinic Terveystalo Turku, Turku</wicri:regionArea><placeName><settlement type="city">Turku</settlement><region type="région" nuts="2">Finlande occidentale</region></placeName></affiliation></author><author><name sortKey="Ventresca, Matthew" sort="Ventresca, Matthew" uniqKey="Ventresca M" first="Matthew" last="Ventresca">Matthew Ventresca</name><affiliation wicri:level="4"><nlm:affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Wallace, Dana" sort="Wallace, Dana" uniqKey="Wallace D" first="Dana" last="Wallace">Dana Wallace</name><affiliation><nlm:affiliation>Nova Southeastern University, Fort Lauderdale, Fla.</nlm:affiliation><wicri:noCountry code="subField">Fla</wicri:noCountry></affiliation></author><author><name sortKey="Waserman, Susan" sort="Waserman, Susan" uniqKey="Waserman S" first="Susan" last="Waserman">Susan Waserman</name><affiliation wicri:level="4"><nlm:affiliation>Division of Clinical Immunology and Allergy, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Division of Clinical Immunology and Allergy, Department of Medicine, McMaster University, Hamilton, Ontario</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Wickman, Magnus" sort="Wickman, Magnus" uniqKey="Wickman M" first="Magnus" last="Wickman">Magnus Wickman</name><affiliation wicri:level="3"><nlm:affiliation>Department of Pediatrics, Sachs' Children's Hospital, South General Hospital and Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Pediatrics, Sachs' Children's Hospital, South General Hospital and Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Wiercioch, Wojtek" sort="Wiercioch, Wojtek" uniqKey="Wiercioch W" first="Wojtek" last="Wiercioch">Wojtek Wiercioch</name><affiliation wicri:level="4"><nlm:affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Yepes Nu Ez, Juan Jose" sort="Yepes Nu Ez, Juan Jose" uniqKey="Yepes Nu Ez J" first="Juan José" last="Yepes-Nu Ez">Juan José Yepes-Nu Ez</name><affiliation wicri:level="4"><nlm:affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; School of Medicine, University of Antioquia, Medellín, Colombia.</nlm:affiliation><country xml:lang="fr">Colombie</country><wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; School of Medicine, University of Antioquia, Medellín</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Zhang, Luo" sort="Zhang, Luo" uniqKey="Zhang L" first="Luo" last="Zhang">Luo Zhang</name><affiliation wicri:level="3"><nlm:affiliation>Department of Otolaryngology Head and Neck Surgery, Beijing TongRen Hospital and Beijing Institute of Otolaryngology, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Otolaryngology Head and Neck Surgery, Beijing TongRen Hospital and Beijing Institute of Otolaryngology, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Zhang, Yuan" sort="Zhang, Yuan" uniqKey="Zhang Y" first="Yuan" last="Zhang">Yuan Zhang</name><affiliation wicri:level="4"><nlm:affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Zidarn, Mihaela" sort="Zidarn, Mihaela" uniqKey="Zidarn M" first="Mihaela" last="Zidarn">Mihaela Zidarn</name><affiliation wicri:level="1"><nlm:affiliation>University Clinic of Pulmonary and Allergic Diseases Golnik, Golnik, Slovenia.</nlm:affiliation><country xml:lang="fr">Slovénie</country><wicri:regionArea>University Clinic of Pulmonary and Allergic Diseases Golnik, Golnik</wicri:regionArea><wicri:noRegion>Golnik</wicri:noRegion></affiliation></author><author><name sortKey="Zuberbier, Torsten" sort="Zuberbier, Torsten" uniqKey="Zuberbier T" first="Torsten" last="Zuberbier">Torsten Zuberbier</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Schunemann, Holger J" sort="Schunemann, Holger J" uniqKey="Schunemann H" first="Holger J" last="Schünemann">Holger J. Schünemann</name><affiliation wicri:level="4"><nlm:affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; Division of General Internal Medicine, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; Division of General Internal Medicine, Department of Medicine, McMaster University, Hamilton, Ontario</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28602936</idno><idno type="pmid">28602936</idno><idno type="doi">10.1016/j.jaci.2017.03.050</idno><idno type="wicri:Area/PubMed/Corpus">000314</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000314</idno><idno type="wicri:Area/PubMed/Curation">000312</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000312</idno><idno type="wicri:Area/PubMed/Checkpoint">000312</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000312</idno><idno type="wicri:Area/Ncbi/Merge">004963</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines-2016 revision.</title><author><name sortKey="Bro Ek, Jan L" sort="Bro Ek, Jan L" uniqKey="Bro Ek J" first="Jan L" last="Bro Ek">Jan L. Bro Ek</name><affiliation wicri:level="4"><nlm:affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; Division of Clinical Immunology and Allergy, Department of Medicine, McMaster University, Hamilton, Ontario, Canada. Electronic address: jan.l.brozek@gmail.com.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; Division of Clinical Immunology and Allergy, Department of Medicine, McMaster University, Hamilton, Ontario</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Bousquet, Jean" sort="Bousquet, Jean" uniqKey="Bousquet J" first="Jean" last="Bousquet">Jean Bousquet</name><affiliation wicri:level="3"><nlm:affiliation>University Hospital, Montpellier, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University Hospital, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Agache, Ioana" sort="Agache, Ioana" uniqKey="Agache I" first="Ioana" last="Agache">Ioana Agache</name><affiliation wicri:level="1"><nlm:affiliation>Faculty of Medicine, Transylvania University, Brasov, Romania.</nlm:affiliation><country xml:lang="fr">Roumanie</country><wicri:regionArea>Faculty of Medicine, Transylvania University, Brasov</wicri:regionArea><wicri:noRegion>Brasov</wicri:noRegion></affiliation></author><author><name sortKey="Agarwal, Arnav" sort="Agarwal, Arnav" uniqKey="Agarwal A" first="Arnav" last="Agarwal">Arnav Agarwal</name><affiliation wicri:level="4"><nlm:affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; School of Medicine, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; School of Medicine, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Bachert, Claus" sort="Bachert, Claus" uniqKey="Bachert C" first="Claus" last="Bachert">Claus Bachert</name><affiliation wicri:level="1"><nlm:affiliation>Upper Airways Research Laboratory, Ghent University Hospital, Ghent, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Upper Airways Research Laboratory, Ghent University Hospital, Ghent</wicri:regionArea><wicri:noRegion>Ghent</wicri:noRegion></affiliation></author><author><name sortKey="Bosnic Anticevich, Sinthia" sort="Bosnic Anticevich, Sinthia" uniqKey="Bosnic Anticevich S" first="Sinthia" last="Bosnic-Anticevich">Sinthia Bosnic-Anticevich</name><affiliation wicri:level="4"><nlm:affiliation>Woolcock Institute, University of Sydney, Sydney, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Woolcock Institute, University of Sydney, Sydney</wicri:regionArea><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region><settlement type="city">Sydney</settlement></placeName><orgName type="university">Université de Sydney</orgName></affiliation></author><author><name sortKey="Brignardello Petersen, Romina" sort="Brignardello Petersen, Romina" uniqKey="Brignardello Petersen R" first="Romina" last="Brignardello-Petersen">Romina Brignardello-Petersen</name><affiliation wicri:level="4"><nlm:affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Canonica, G Walter" sort="Canonica, G Walter" uniqKey="Canonica G" first="G Walter" last="Canonica">G Walter Canonica</name><affiliation wicri:level="3"><nlm:affiliation>Asthma & Allergy Clinic, Humanitas University, Rozzano, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Asthma & Allergy Clinic, Humanitas University, Rozzano, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Casale, Thomas" sort="Casale, Thomas" uniqKey="Casale T" first="Thomas" last="Casale">Thomas Casale</name><affiliation wicri:level="4"><nlm:affiliation>Division of Allergy and Immunology, University of South Florida, Tampa, Fla.</nlm:affiliation><orgName type="university">Université de Floride du Sud</orgName><country>États-Unis</country><placeName><settlement type="city">Tampa</settlement><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Chavannes, Niels H" sort="Chavannes, Niels H" uniqKey="Chavannes N" first="Niels H" last="Chavannes">Niels H. Chavannes</name><affiliation wicri:level="3"><nlm:affiliation>Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Public Health and Primary Care, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Correia De Sousa, Jaime" sort="Correia De Sousa, Jaime" uniqKey="Correia De Sousa J" first="Jaime" last="Correia De Sousa">Jaime Correia De Sousa</name><affiliation wicri:level="4"><nlm:affiliation>Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, and ICVS/3B's-PT Government Associate Laboratory, Braga/Guimarães, Portugal.</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, and ICVS/3B's-PT Government Associate Laboratory, Braga/Guimarães</wicri:regionArea><orgName type="university">Université du Minho</orgName><placeName><settlement type="city">Braga</settlement><region>Région Nord (Portugal)</region></placeName></affiliation></author><author><name sortKey="Cruz, Alvaro A" sort="Cruz, Alvaro A" uniqKey="Cruz A" first="Alvaro A" last="Cruz">Alvaro A. Cruz</name><affiliation wicri:level="1"><nlm:affiliation>ProAR-Center of Excellence for Asthma, Federal University of Bahia, Salvador, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>ProAR-Center of Excellence for Asthma, Federal University of Bahia, Salvador</wicri:regionArea><wicri:noRegion>Salvador</wicri:noRegion></affiliation></author><author><name sortKey="Cuello Garcia, Carlos A" sort="Cuello Garcia, Carlos A" uniqKey="Cuello Garcia C" first="Carlos A" last="Cuello-Garcia">Carlos A. Cuello-Garcia</name><affiliation wicri:level="4"><nlm:affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Demoly, Pascal" sort="Demoly, Pascal" uniqKey="Demoly P" first="Pascal" last="Demoly">Pascal Demoly</name><affiliation wicri:level="3"><nlm:affiliation>University Hospital of Montpellier, Montpellier, and Sorbonne Universités, UPMC Paris 06, UMR-S 1136, IPLESP, Equipe EPAR, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University Hospital of Montpellier, Montpellier, and Sorbonne Universités, UPMC Paris 06, UMR-S 1136, IPLESP, Equipe EPAR, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Dykewicz, Mark" sort="Dykewicz, Mark" uniqKey="Dykewicz M" first="Mark" last="Dykewicz">Mark Dykewicz</name><affiliation><nlm:affiliation>Section of Allergy and Immunology, Department of Internal Medicine, Saint Louis University School of Medicine, St Louis, Mo.</nlm:affiliation><wicri:noCountry code="subField">Mo</wicri:noCountry></affiliation></author><author><name sortKey="Etxeandia Ikobaltzeta, Itziar" sort="Etxeandia Ikobaltzeta, Itziar" uniqKey="Etxeandia Ikobaltzeta I" first="Itziar" last="Etxeandia-Ikobaltzeta">Itziar Etxeandia-Ikobaltzeta</name><affiliation wicri:level="4"><nlm:affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; Dirección de Investigación e Innovación Sanitaria, Departamento de Salud, Gobierno Vasco-Eusko Jaurlaritza, Vitoria-Gasteiz, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; Dirección de Investigación e Innovación Sanitaria, Departamento de Salud, Gobierno Vasco-Eusko Jaurlaritza, Vitoria-Gasteiz</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Florez, Ivan D" sort="Florez, Ivan D" uniqKey="Florez I" first="Ivan D" last="Florez">Ivan D. Florez</name><affiliation wicri:level="4"><nlm:affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; Department of Pediatrics, University of Antioquia, Medellin, Colombia.</nlm:affiliation><country xml:lang="fr">Colombie</country><wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; Department of Pediatrics, University of Antioquia, Medellin</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Fokkens, Wytske" sort="Fokkens, Wytske" uniqKey="Fokkens W" first="Wytske" last="Fokkens">Wytske Fokkens</name><affiliation wicri:level="3"><nlm:affiliation>Department of Otorhinolaryngology, Academic Medical Centre, Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Otorhinolaryngology, Academic Medical Centre, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Fonseca, Joao" sort="Fonseca, Joao" uniqKey="Fonseca J" first="Joao" last="Fonseca">Joao Fonseca</name><affiliation wicri:level="1"><nlm:affiliation>CINTESIS-Center for Health Technology and Services Research, Faculdade de Medicina, Universidade do Porto & Allergy, CUF Porto Hospital and Instituto, Porto, Portugal.</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>CINTESIS-Center for Health Technology and Services Research, Faculdade de Medicina, Universidade do Porto & Allergy, CUF Porto Hospital and Instituto, Porto</wicri:regionArea><wicri:noRegion>Porto</wicri:noRegion></affiliation></author><author><name sortKey="Hellings, Peter W" sort="Hellings, Peter W" uniqKey="Hellings P" first="Peter W" last="Hellings">Peter W. Hellings</name><affiliation wicri:level="3"><nlm:affiliation>Department of Otorhinolaryngology, University Hospitals Leuven, and the Department of Otorhinolaryngology, Academic Medical Center (AMC), Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Otorhinolaryngology, University Hospitals Leuven, and the Department of Otorhinolaryngology, Academic Medical Center (AMC), Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Klimek, Ludger" sort="Klimek, Ludger" uniqKey="Klimek L" first="Ludger" last="Klimek">Ludger Klimek</name><affiliation wicri:level="1"><nlm:affiliation>Center of Rhinology and Allergology, Wiesbaden, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Center of Rhinology and Allergology, Wiesbaden</wicri:regionArea><wicri:noRegion>Wiesbaden</wicri:noRegion><wicri:noRegion>Wiesbaden</wicri:noRegion><wicri:noRegion>Wiesbaden</wicri:noRegion></affiliation></author><author><name sortKey="Kowalski, Sergio" sort="Kowalski, Sergio" uniqKey="Kowalski S" first="Sergio" last="Kowalski">Sergio Kowalski</name><affiliation wicri:level="4"><nlm:affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Kuna, Piotr" sort="Kuna, Piotr" uniqKey="Kuna P" first="Piotr" last="Kuna">Piotr Kuna</name><affiliation wicri:level="1"><nlm:affiliation>Division of Internal Medicine Asthma and Allergy, Faculty of Medicine, Medical University of Lodz, Lodz, Poland.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Division of Internal Medicine Asthma and Allergy, Faculty of Medicine, Medical University of Lodz, Lodz</wicri:regionArea><wicri:noRegion>Lodz</wicri:noRegion></affiliation></author><author><name sortKey="Laisaar, Kaja Triin" sort="Laisaar, Kaja Triin" uniqKey="Laisaar K" first="Kaja-Triin" last="Laisaar">Kaja-Triin Laisaar</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Family Medicine and Public Health, University of Tartu, Tartu, Estonia.</nlm:affiliation><country xml:lang="fr">Estonie</country><wicri:regionArea>Institute of Family Medicine and Public Health, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation></author><author><name sortKey="Larenas Linnemann, Desiree E" sort="Larenas Linnemann, Desiree E" uniqKey="Larenas Linnemann D" first="Désirée E" last="Larenas-Linnemann">Désirée E. Larenas-Linnemann</name><affiliation wicri:level="1"><nlm:affiliation>Hospital Médica Sur, Mexico City, Mexico.</nlm:affiliation><country xml:lang="fr">Mexique</country><wicri:regionArea>Hospital Médica Sur, Mexico City</wicri:regionArea><wicri:noRegion>Mexico City</wicri:noRegion></affiliation></author><author><name sortKey="L Drup Carlsen, Karin C" sort="L Drup Carlsen, Karin C" uniqKey="L Drup Carlsen K" first="Karin C" last="L Drup Carlsen">Karin C. L Drup Carlsen</name><affiliation wicri:level="3"><nlm:affiliation>Department of Paediatrics, Oslo University Hospital, University of Oslo, Oslo, Norway.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Paediatrics, Oslo University Hospital, University of Oslo, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation></author><author><name sortKey="Manning, Peter J" sort="Manning, Peter J" uniqKey="Manning P" first="Peter J" last="Manning">Peter J. Manning</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, Royal College of Surgeons in Ireland Medical School, Dublin, Ireland.</nlm:affiliation><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Department of Medicine, Royal College of Surgeons in Ireland Medical School, Dublin</wicri:regionArea><wicri:noRegion>Dublin</wicri:noRegion></affiliation></author><author><name sortKey="Meltzer, Eli" sort="Meltzer, Eli" uniqKey="Meltzer E" first="Eli" last="Meltzer">Eli Meltzer</name><affiliation><nlm:affiliation>Department of Pediatrics, Division of Allergy & Immunology, University of California, San Diego, Calif.</nlm:affiliation><wicri:noCountry code="subField">Calif</wicri:noCountry></affiliation></author><author><name sortKey="Mullol, Joaquim" sort="Mullol, Joaquim" uniqKey="Mullol J" first="Joaquim" last="Mullol">Joaquim Mullol</name><affiliation wicri:level="3"><nlm:affiliation>Unitat de Rinologia i Clínica de l'Olfacte, Servei d'ORL, Hospital Clínic, Clinical & Experimental Respiratory Immunoallergy, IDIBAPS, Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Unitat de Rinologia i Clínica de l'Olfacte, Servei d'ORL, Hospital Clínic, Clinical & Experimental Respiratory Immunoallergy, IDIBAPS, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Muraro, Antonella" sort="Muraro, Antonella" uniqKey="Muraro A" first="Antonella" last="Muraro">Antonella Muraro</name><affiliation wicri:level="1"><nlm:affiliation>Department of Women and Child Health & Food Allergy Referral Centre Veneto Region, University of Padua, Padua, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Women and Child Health & Food Allergy Referral Centre Veneto Region, University of Padua, Padua</wicri:regionArea><wicri:noRegion>Padua</wicri:noRegion></affiliation></author><author><name sortKey="O Hehir, Robyn" sort="O Hehir, Robyn" uniqKey="O Hehir R" first="Robyn" last="O'Hehir">Robyn O'Hehir</name><affiliation wicri:level="3"><nlm:affiliation>Alfred Hospital and Monash University, Melbourne, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Alfred Hospital and Monash University, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Ohta, Ken" sort="Ohta, Ken" uniqKey="Ohta K" first="Ken" last="Ohta">Ken Ohta</name><affiliation wicri:level="3"><nlm:affiliation>National Hospital Organization Tokyo National Hospital, Kiyose-city, Tokyo, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>National Hospital Organization Tokyo National Hospital, Kiyose-city, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region></placeName></affiliation></author><author><name sortKey="Panzner, Petr" sort="Panzner, Petr" uniqKey="Panzner P" first="Petr" last="Panzner">Petr Panzner</name><affiliation wicri:level="3"><nlm:affiliation>Department of Immunology and Allergology, Faculty of Medicine in Pilsen, Charles University in Prague, Prague, Czech Republic.</nlm:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Department of Immunology and Allergology, Faculty of Medicine in Pilsen, Charles University in Prague, Prague</wicri:regionArea><placeName><settlement type="city">Prague</settlement><region type="région" nuts="2">Bohême centrale</region></placeName></affiliation></author><author><name sortKey="Papadopoulos, Nikolaos" sort="Papadopoulos, Nikolaos" uniqKey="Papadopoulos N" first="Nikolaos" last="Papadopoulos">Nikolaos Papadopoulos</name><affiliation wicri:level="3"><nlm:affiliation>Allergy Department, 2nd Pediatric Clinic, University of Athens, Athens, Greece; Division of Infection, Immunity & Respiratory Medicine, University of Manchester, Manchester, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Allergy Department, 2nd Pediatric Clinic, University of Athens, Athens, Greece; Division of Infection, Immunity & Respiratory Medicine, University of Manchester, Manchester</wicri:regionArea><placeName><settlement type="city">Manchester</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Manchester</region></placeName></affiliation></author><author><name sortKey="Park, Hae Sim" sort="Park, Hae Sim" uniqKey="Park H" first="Hae-Sim" last="Park">Hae-Sim Park</name><affiliation wicri:level="1"><nlm:affiliation>Department of Allergy and Rheumatology, Ajou University School of Medicine, Suwon, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Allergy and Rheumatology, Ajou University School of Medicine, Suwon</wicri:regionArea><wicri:noRegion>Suwon</wicri:noRegion></affiliation></author><author><name sortKey="Passalacqua, Gianni" sort="Passalacqua, Gianni" uniqKey="Passalacqua G" first="Gianni" last="Passalacqua">Gianni Passalacqua</name><affiliation wicri:level="1"><nlm:affiliation>Allergy and Respiratory Diseases, IRCCS San Martino, IST, University of Genoa, Genoa, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Allergy and Respiratory Diseases, IRCCS San Martino, IST, University of Genoa, Genoa</wicri:regionArea><wicri:noRegion>Genoa</wicri:noRegion></affiliation></author><author><name sortKey="Pawankar, Ruby" sort="Pawankar, Ruby" uniqKey="Pawankar R" first="Ruby" last="Pawankar">Ruby Pawankar</name><affiliation wicri:level="3"><nlm:affiliation>Department of Pediatrics, Nippon Medical School, Tokyo, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Pediatrics, Nippon Medical School, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region></placeName></affiliation></author><author><name sortKey="Price, David" sort="Price, David" uniqKey="Price D" first="David" last="Price">David Price</name><affiliation wicri:level="1"><nlm:affiliation>University of Aberdeen, Aberdeen, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>University of Aberdeen, Aberdeen</wicri:regionArea><wicri:noRegion>Aberdeen</wicri:noRegion></affiliation></author><author><name sortKey="Riva, John J" sort="Riva, John J" uniqKey="Riva J" first="John J" last="Riva">John J. Riva</name><affiliation wicri:level="4"><nlm:affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; Department of Family Medicine, McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; Department of Family Medicine, McMaster University, Hamilton, Ontario</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Roldan, Yetiani" sort="Roldan, Yetiani" uniqKey="Roldan Y" first="Yetiani" last="Roldán">Yetiani Roldán</name><affiliation wicri:level="4"><nlm:affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Ryan, Dermot" sort="Ryan, Dermot" uniqKey="Ryan D" first="Dermot" last="Ryan">Dermot Ryan</name><affiliation wicri:level="4"><nlm:affiliation>Allergy and Respiratory Research Group, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Allergy and Respiratory Research Group, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Sadeghirad, Behnam" sort="Sadeghirad, Behnam" uniqKey="Sadeghirad B" first="Behnam" last="Sadeghirad">Behnam Sadeghirad</name><affiliation wicri:level="1"><nlm:affiliation>HIV/STI Surveillance Research Center, and World Health Organization Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran.</nlm:affiliation><country xml:lang="fr">Iran</country><wicri:regionArea>HIV/STI Surveillance Research Center, and World Health Organization Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman</wicri:regionArea><wicri:noRegion>Kerman</wicri:noRegion></affiliation></author><author><name sortKey="Samolinski, Boleslaw" sort="Samolinski, Boleslaw" uniqKey="Samolinski B" first="Boleslaw" last="Samolinski">Boleslaw Samolinski</name><affiliation wicri:level="1"><nlm:affiliation>Department of Prevention of Environmental Hazards and Allergology, Medical University of Warsaw, Warsaw, Poland.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Prevention of Environmental Hazards and Allergology, Medical University of Warsaw, Warsaw</wicri:regionArea><wicri:noRegion>Warsaw</wicri:noRegion></affiliation></author><author><name sortKey="Schmid Grendelmeier, Peter" sort="Schmid Grendelmeier, Peter" uniqKey="Schmid Grendelmeier P" first="Peter" last="Schmid-Grendelmeier">Peter Schmid-Grendelmeier</name><affiliation wicri:level="1"><nlm:affiliation>Allergy Unit, Department of Dermatology, University Hospital of Zürich and Christine Kühne Center for Allergy Research and Education CK-CARE, Davos, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Allergy Unit, Department of Dermatology, University Hospital of Zürich and Christine Kühne Center for Allergy Research and Education CK-CARE, Davos</wicri:regionArea><wicri:noRegion>Davos</wicri:noRegion></affiliation></author><author><name sortKey="Sheikh, Aziz" sort="Sheikh, Aziz" uniqKey="Sheikh A" first="Aziz" last="Sheikh">Aziz Sheikh</name><affiliation wicri:level="4"><nlm:affiliation>Asthma UK Centre for Applied Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Asthma UK Centre for Applied Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Togias, Alkis" sort="Togias, Alkis" uniqKey="Togias A" first="Alkis" last="Togias">Alkis Togias</name><affiliation><nlm:affiliation>Asthma and Inflammation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.</nlm:affiliation><wicri:noCountry code="subField">Md</wicri:noCountry></affiliation></author><author><name sortKey="Valero, Antonio" sort="Valero, Antonio" uniqKey="Valero A" first="Antonio" last="Valero">Antonio Valero</name><affiliation wicri:level="3"><nlm:affiliation>Department of Pneumology and Allergy, Immunoallèrgia Respiratòria Clínica I Experimental (IDIBAPS), Centro de Investigaciones Biomédicas en Red de Enfermedades Respiratorias (CIBERES), Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Pneumology and Allergy, Immunoallèrgia Respiratòria Clínica I Experimental (IDIBAPS), Centro de Investigaciones Biomédicas en Red de Enfermedades Respiratorias (CIBERES), Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Valiulis, Arunas" sort="Valiulis, Arunas" uniqKey="Valiulis A" first="Arunas" last="Valiulis">Arunas Valiulis</name><affiliation wicri:level="3"><nlm:affiliation>Vilnius University Clinic of Children's Diseases and Public Health Institute, Vilnius, and the European Academy of Paediatrics (EAP/UEMS-SP), Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Vilnius University Clinic of Children's Diseases and Public Health Institute, Vilnius, and the European Academy of Paediatrics (EAP/UEMS-SP), Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation></author><author><name sortKey="Valovirta, Erkka" sort="Valovirta, Erkka" uniqKey="Valovirta E" first="Erkka" last="Valovirta">Erkka Valovirta</name><affiliation wicri:level="3"><nlm:affiliation>Department of Lung Diseases and Clinical Immunology, University of Turku and Allergy Clinic Terveystalo Turku, Turku, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Lung Diseases and Clinical Immunology, University of Turku and Allergy Clinic Terveystalo Turku, Turku</wicri:regionArea><placeName><settlement type="city">Turku</settlement><region type="région" nuts="2">Finlande occidentale</region></placeName></affiliation></author><author><name sortKey="Ventresca, Matthew" sort="Ventresca, Matthew" uniqKey="Ventresca M" first="Matthew" last="Ventresca">Matthew Ventresca</name><affiliation wicri:level="4"><nlm:affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Wallace, Dana" sort="Wallace, Dana" uniqKey="Wallace D" first="Dana" last="Wallace">Dana Wallace</name><affiliation><nlm:affiliation>Nova Southeastern University, Fort Lauderdale, Fla.</nlm:affiliation><wicri:noCountry code="subField">Fla</wicri:noCountry></affiliation></author><author><name sortKey="Waserman, Susan" sort="Waserman, Susan" uniqKey="Waserman S" first="Susan" last="Waserman">Susan Waserman</name><affiliation wicri:level="4"><nlm:affiliation>Division of Clinical Immunology and Allergy, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Division of Clinical Immunology and Allergy, Department of Medicine, McMaster University, Hamilton, Ontario</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Wickman, Magnus" sort="Wickman, Magnus" uniqKey="Wickman M" first="Magnus" last="Wickman">Magnus Wickman</name><affiliation wicri:level="3"><nlm:affiliation>Department of Pediatrics, Sachs' Children's Hospital, South General Hospital and Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Pediatrics, Sachs' Children's Hospital, South General Hospital and Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Wiercioch, Wojtek" sort="Wiercioch, Wojtek" uniqKey="Wiercioch W" first="Wojtek" last="Wiercioch">Wojtek Wiercioch</name><affiliation wicri:level="4"><nlm:affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Yepes Nu Ez, Juan Jose" sort="Yepes Nu Ez, Juan Jose" uniqKey="Yepes Nu Ez J" first="Juan José" last="Yepes-Nu Ez">Juan José Yepes-Nu Ez</name><affiliation wicri:level="4"><nlm:affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; School of Medicine, University of Antioquia, Medellín, Colombia.</nlm:affiliation><country xml:lang="fr">Colombie</country><wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; School of Medicine, University of Antioquia, Medellín</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Zhang, Luo" sort="Zhang, Luo" uniqKey="Zhang L" first="Luo" last="Zhang">Luo Zhang</name><affiliation wicri:level="3"><nlm:affiliation>Department of Otolaryngology Head and Neck Surgery, Beijing TongRen Hospital and Beijing Institute of Otolaryngology, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Otolaryngology Head and Neck Surgery, Beijing TongRen Hospital and Beijing Institute of Otolaryngology, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Zhang, Yuan" sort="Zhang, Yuan" uniqKey="Zhang Y" first="Yuan" last="Zhang">Yuan Zhang</name><affiliation wicri:level="4"><nlm:affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Zidarn, Mihaela" sort="Zidarn, Mihaela" uniqKey="Zidarn M" first="Mihaela" last="Zidarn">Mihaela Zidarn</name><affiliation wicri:level="1"><nlm:affiliation>University Clinic of Pulmonary and Allergic Diseases Golnik, Golnik, Slovenia.</nlm:affiliation><country xml:lang="fr">Slovénie</country><wicri:regionArea>University Clinic of Pulmonary and Allergic Diseases Golnik, Golnik</wicri:regionArea><wicri:noRegion>Golnik</wicri:noRegion></affiliation></author><author><name sortKey="Zuberbier, Torsten" sort="Zuberbier, Torsten" uniqKey="Zuberbier T" first="Torsten" last="Zuberbier">Torsten Zuberbier</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Schunemann, Holger J" sort="Schunemann, Holger J" uniqKey="Schunemann H" first="Holger J" last="Schünemann">Holger J. Schünemann</name><affiliation wicri:level="4"><nlm:affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; Division of General Internal Medicine, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; Division of General Internal Medicine, Department of Medicine, McMaster University, Hamilton, Ontario</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author></analytic><series><title level="j">The Journal of allergy and clinical immunology</title><idno type="eISSN">1097-6825</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Anti-Allergic Agents (therapeutic use)</term><term>Asthma (prevention & control)</term><term>Child</term><term>Clinical Decision-Making</term><term>Evidence-Based Practice</term><term>Histamine H1 Antagonists (therapeutic use)</term><term>Humans</term><term>Quality of Life</term><term>Rhinitis, Allergic (drug therapy)</term><term>Rhinitis, Allergic (epidemiology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Antiallergiques (usage thérapeutique)</term><term>Antihistaminiques des récepteurs H1 (usage thérapeutique)</term><term>Asthme ()</term><term>Enfant</term><term>Humains</term><term>Pratique factuelle</term><term>Prise de décision clinique</term><term>Qualité de vie</term><term>Rhinite allergique (traitement médicamenteux)</term><term>Rhinite allergique (épidémiologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Anti-Allergic Agents</term><term>Histamine H1 Antagonists</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Rhinitis, Allergic</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Rhinitis, Allergic</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Asthma</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Rhinite allergique</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Antiallergiques</term><term>Antihistaminiques des récepteurs H1</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Rhinite allergique</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Child</term><term>Clinical Decision-Making</term><term>Evidence-Based Practice</term><term>Humans</term><term>Quality of Life</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Asthme</term><term>Enfant</term><term>Humains</term><term>Pratique factuelle</term><term>Prise de décision clinique</term><term>Qualité de vie</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Allergic rhinitis (AR) affects 10% to 40% of the population. It reduces quality of life and school and work performance and is a frequent reason for office visits in general practice. Medical costs are large, but avoidable costs associated with lost work productivity are even larger than those incurred by asthma. New evidence has accumulated since the last revision of the Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines in 2010, prompting its update.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">28602936</PMID><DateCreated><Year>2017</Year><Month>06</Month><Day>12</Day></DateCreated><DateCompleted><Year>2017</Year><Month>10</Month><Day>23</Day></DateCompleted><DateRevised><Year>2017</Year><Month>10</Month><Day>23</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1097-6825</ISSN><JournalIssue CitedMedium="Internet"><Volume>140</Volume><Issue>4</Issue><PubDate><Year>2017</Year><Month>Oct</Month></PubDate></JournalIssue><Title>The Journal of allergy and clinical immunology</Title><ISOAbbreviation>J. Allergy Clin. Immunol.</ISOAbbreviation></Journal><ArticleTitle>Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines-2016 revision.</ArticleTitle><Pagination><MedlinePgn>950-958</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0091-6749(17)30919-3</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jaci.2017.03.050</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Allergic rhinitis (AR) affects 10% to 40% of the population. It reduces quality of life and school and work performance and is a frequent reason for office visits in general practice. Medical costs are large, but avoidable costs associated with lost work productivity are even larger than those incurred by asthma. New evidence has accumulated since the last revision of the Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines in 2010, prompting its update.</AbstractText><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">We sought to provide a targeted update of the ARIA guidelines.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">The ARIA guideline panel identified new clinical questions and selected questions requiring an update. We performed systematic reviews of health effects and the evidence about patients' values and preferences and resource requirements (up to June 2016). We followed the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) evidence-to-decision frameworks to develop recommendations.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">The 2016 revision of the ARIA guidelines provides both updated and new recommendations about the pharmacologic treatment of AR. Specifically, it addresses the relative merits of using oral H1-antihistamines, intranasal H1-antihistamines, intranasal corticosteroids, and leukotriene receptor antagonists either alone or in combination. The ARIA guideline panel provides specific recommendations for the choice of treatment and the rationale for the choice and discusses specific considerations that clinicians and patients might want to review to choose the management most appropriate for an individual patient.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Appropriate treatment of AR might improve patients' quality of life and school and work productivity. ARIA recommendations support patients, their caregivers, and health care providers in choosing the optimal treatment.</AbstractText><CopyrightInformation>Copyright © 2017 American Academy of Allergy, Asthma & Immunology. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Brożek</LastName><ForeName>Jan L</ForeName><Initials>JL</Initials><AffiliationInfo><Affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; Division of Clinical Immunology and Allergy, Department of Medicine, McMaster University, Hamilton, Ontario, Canada. Electronic address: jan.l.brozek@gmail.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bousquet</LastName><ForeName>Jean</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>University Hospital, Montpellier, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Agache</LastName><ForeName>Ioana</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Faculty of Medicine, Transylvania University, Brasov, Romania.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Agarwal</LastName><ForeName>Arnav</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; School of Medicine, University of Toronto, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bachert</LastName><ForeName>Claus</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Upper Airways Research Laboratory, Ghent University Hospital, Ghent, Belgium.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bosnic-Anticevich</LastName><ForeName>Sinthia</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Woolcock Institute, University of Sydney, Sydney, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Brignardello-Petersen</LastName><ForeName>Romina</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Canonica</LastName><ForeName>G Walter</ForeName><Initials>GW</Initials><AffiliationInfo><Affiliation>Asthma & Allergy Clinic, Humanitas University, Rozzano, Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Casale</LastName><ForeName>Thomas</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Division of Allergy and Immunology, University of South Florida, Tampa, Fla.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chavannes</LastName><ForeName>Niels H</ForeName><Initials>NH</Initials><AffiliationInfo><Affiliation>Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Correia de Sousa</LastName><ForeName>Jaime</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, and ICVS/3B's-PT Government Associate Laboratory, Braga/Guimarães, Portugal.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cruz</LastName><ForeName>Alvaro A</ForeName><Initials>AA</Initials><AffiliationInfo><Affiliation>ProAR-Center of Excellence for Asthma, Federal University of Bahia, Salvador, Brazil.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cuello-Garcia</LastName><ForeName>Carlos A</ForeName><Initials>CA</Initials><AffiliationInfo><Affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Demoly</LastName><ForeName>Pascal</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>University Hospital of Montpellier, Montpellier, and Sorbonne Universités, UPMC Paris 06, UMR-S 1136, IPLESP, Equipe EPAR, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dykewicz</LastName><ForeName>Mark</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Section of Allergy and Immunology, Department of Internal Medicine, Saint Louis University School of Medicine, St Louis, Mo.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Etxeandia-Ikobaltzeta</LastName><ForeName>Itziar</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; Dirección de Investigación e Innovación Sanitaria, Departamento de Salud, Gobierno Vasco-Eusko Jaurlaritza, Vitoria-Gasteiz, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Florez</LastName><ForeName>Ivan D</ForeName><Initials>ID</Initials><AffiliationInfo><Affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; Department of Pediatrics, University of Antioquia, Medellin, Colombia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fokkens</LastName><ForeName>Wytske</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>Department of Otorhinolaryngology, Academic Medical Centre, Amsterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fonseca</LastName><ForeName>Joao</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>CINTESIS-Center for Health Technology and Services Research, Faculdade de Medicina, Universidade do Porto & Allergy, CUF Porto Hospital and Instituto, Porto, Portugal.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hellings</LastName><ForeName>Peter W</ForeName><Initials>PW</Initials><AffiliationInfo><Affiliation>Department of Otorhinolaryngology, University Hospitals Leuven, and the Department of Otorhinolaryngology, Academic Medical Center (AMC), Amsterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Klimek</LastName><ForeName>Ludger</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Center of Rhinology and Allergology, Wiesbaden, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kowalski</LastName><ForeName>Sergio</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kuna</LastName><ForeName>Piotr</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Division of Internal Medicine Asthma and Allergy, Faculty of Medicine, Medical University of Lodz, Lodz, Poland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Laisaar</LastName><ForeName>Kaja-Triin</ForeName><Initials>KT</Initials><AffiliationInfo><Affiliation>Institute of Family Medicine and Public Health, University of Tartu, Tartu, Estonia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Larenas-Linnemann</LastName><ForeName>Désirée E</ForeName><Initials>DE</Initials><AffiliationInfo><Affiliation>Hospital Médica Sur, Mexico City, Mexico.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lødrup Carlsen</LastName><ForeName>Karin C</ForeName><Initials>KC</Initials><AffiliationInfo><Affiliation>Department of Paediatrics, Oslo University Hospital, University of Oslo, Oslo, Norway.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Manning</LastName><ForeName>Peter J</ForeName><Initials>PJ</Initials><AffiliationInfo><Affiliation>Department of Medicine, Royal College of Surgeons in Ireland Medical School, Dublin, Ireland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Meltzer</LastName><ForeName>Eli</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Department of Pediatrics, Division of Allergy & Immunology, University of California, San Diego, Calif.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mullol</LastName><ForeName>Joaquim</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Unitat de Rinologia i Clínica de l'Olfacte, Servei d'ORL, Hospital Clínic, Clinical & Experimental Respiratory Immunoallergy, IDIBAPS, Barcelona, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Muraro</LastName><ForeName>Antonella</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Women and Child Health & Food Allergy Referral Centre Veneto Region, University of Padua, Padua, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>O'Hehir</LastName><ForeName>Robyn</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Alfred Hospital and Monash University, Melbourne, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ohta</LastName><ForeName>Ken</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>National Hospital Organization Tokyo National Hospital, Kiyose-city, Tokyo, Japan.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Panzner</LastName><ForeName>Petr</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Immunology and Allergology, Faculty of Medicine in Pilsen, Charles University in Prague, Prague, Czech Republic.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Papadopoulos</LastName><ForeName>Nikolaos</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Allergy Department, 2nd Pediatric Clinic, University of Athens, Athens, Greece; Division of Infection, Immunity & Respiratory Medicine, University of Manchester, Manchester, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Park</LastName><ForeName>Hae-Sim</ForeName><Initials>HS</Initials><AffiliationInfo><Affiliation>Department of Allergy and Rheumatology, Ajou University School of Medicine, Suwon, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Passalacqua</LastName><ForeName>Gianni</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Allergy and Respiratory Diseases, IRCCS San Martino, IST, University of Genoa, Genoa, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pawankar</LastName><ForeName>Ruby</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Department of Pediatrics, Nippon Medical School, Tokyo, Japan.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Price</LastName><ForeName>David</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>University of Aberdeen, Aberdeen, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Riva</LastName><ForeName>John J</ForeName><Initials>JJ</Initials><AffiliationInfo><Affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; Department of Family Medicine, McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Roldán</LastName><ForeName>Yetiani</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ryan</LastName><ForeName>Dermot</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Allergy and Respiratory Research Group, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sadeghirad</LastName><ForeName>Behnam</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>HIV/STI Surveillance Research Center, and World Health Organization Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Samolinski</LastName><ForeName>Boleslaw</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Department of Prevention of Environmental Hazards and Allergology, Medical University of Warsaw, Warsaw, Poland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schmid-Grendelmeier</LastName><ForeName>Peter</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Allergy Unit, Department of Dermatology, University Hospital of Zürich and Christine Kühne Center for Allergy Research and Education CK-CARE, Davos, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sheikh</LastName><ForeName>Aziz</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Asthma UK Centre for Applied Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Togias</LastName><ForeName>Alkis</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Asthma and Inflammation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Valero</LastName><ForeName>Antonio</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Pneumology and Allergy, Immunoallèrgia Respiratòria Clínica I Experimental (IDIBAPS), Centro de Investigaciones Biomédicas en Red de Enfermedades Respiratorias (CIBERES), Barcelona, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Valiulis</LastName><ForeName>Arunas</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Vilnius University Clinic of Children's Diseases and Public Health Institute, Vilnius, and the European Academy of Paediatrics (EAP/UEMS-SP), Brussels, Belgium.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Valovirta</LastName><ForeName>Erkka</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Department of Lung Diseases and Clinical Immunology, University of Turku and Allergy Clinic Terveystalo Turku, Turku, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ventresca</LastName><ForeName>Matthew</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wallace</LastName><ForeName>Dana</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Nova Southeastern University, Fort Lauderdale, Fla.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Waserman</LastName><ForeName>Susan</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Division of Clinical Immunology and Allergy, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wickman</LastName><ForeName>Magnus</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Pediatrics, Sachs' Children's Hospital, South General Hospital and Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wiercioch</LastName><ForeName>Wojtek</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yepes-Nuñez</LastName><ForeName>Juan José</ForeName><Initials>JJ</Initials><AffiliationInfo><Affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; School of Medicine, University of Antioquia, Medellín, Colombia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Luo</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Otolaryngology Head and Neck Surgery, Beijing TongRen Hospital and Beijing Institute of Otolaryngology, Beijing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Yuan</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zidarn</LastName><ForeName>Mihaela</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>University Clinic of Pulmonary and Allergic Diseases Golnik, Golnik, Slovenia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zuberbier</LastName><ForeName>Torsten</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Berlin, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schünemann</LastName><ForeName>Holger J</ForeName><Initials>HJ</Initials><AffiliationInfo><Affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; Division of General Internal Medicine, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D017065">Practice Guideline</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>06</Month><Day>08</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>J Allergy Clin Immunol</MedlineTA><NlmUniqueID>1275002</NlmUniqueID><ISSNLinking>0091-6749</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D018926">Anti-Allergic Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D006634">Histamine H1 Antagonists</NameOfSubstance></Chemical></ChemicalList><CitationSubset>AIM</CitationSubset><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018926" MajorTopicYN="N">Anti-Allergic Agents</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001249" MajorTopicYN="N">Asthma</DescriptorName><QualifierName UI="Q000517" MajorTopicYN="Y">prevention & control</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002648" MajorTopicYN="N">Child</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000066491" MajorTopicYN="N">Clinical Decision-Making</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D055317" MajorTopicYN="N">Evidence-Based Practice</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006634" MajorTopicYN="N">Histamine H1 Antagonists</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011788" MajorTopicYN="N">Quality of Life</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D065631" MajorTopicYN="N">Rhinitis, Allergic</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Allergic rhinitis</Keyword><Keyword MajorTopicYN="N">practice guideline</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year><Month>10</Month><Day>03</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2017</Year><Month>02</Month><Day>12</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2017</Year><Month>03</Month><Day>15</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>6</Month><Day>13</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>10</Month><Day>24</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>6</Month><Day>13</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28602936</ArticleId><ArticleId IdType="pii">S0091-6749(17)30919-3</ArticleId><ArticleId IdType="doi">10.1016/j.jaci.2017.03.050</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Belgique</li><li>Brésil</li><li>Canada</li><li>Colombie</li><li>Corée du Sud</li><li>Espagne</li><li>Estonie</li><li>Finlande</li><li>France</li><li>Iran</li><li>Irlande (pays)</li><li>Italie</li><li>Japon</li><li>Mexique</li><li>Norvège</li><li>Pays-Bas</li><li>Pologne</li><li>Portugal</li><li>Roumanie</li><li>Royaume-Uni</li><li>République populaire de Chine</li><li>République tchèque</li><li>Slovénie</li><li>Suisse</li><li>Suède</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Berlin</li><li>Bohême centrale</li><li>Catalogne</li><li>Finlande occidentale</li><li>Floride</li><li>Grand Manchester</li><li>Hollande-Méridionale</li><li>Hollande-Septentrionale</li><li>Languedoc-Roussillon</li><li>Lombardie</li><li>Nouvelle-Galles du Sud</li><li>Occitanie (région 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Bro Ek</name></region><name sortKey="Agarwal, Arnav" sort="Agarwal, Arnav" uniqKey="Agarwal A" first="Arnav" last="Agarwal">Arnav Agarwal</name><name sortKey="Brignardello Petersen, Romina" sort="Brignardello Petersen, Romina" uniqKey="Brignardello Petersen R" first="Romina" last="Brignardello-Petersen">Romina Brignardello-Petersen</name><name sortKey="Cuello Garcia, Carlos A" sort="Cuello Garcia, Carlos A" uniqKey="Cuello Garcia C" first="Carlos A" last="Cuello-Garcia">Carlos A. Cuello-Garcia</name><name sortKey="Kowalski, Sergio" sort="Kowalski, Sergio" uniqKey="Kowalski S" first="Sergio" last="Kowalski">Sergio Kowalski</name><name sortKey="Riva, John J" sort="Riva, John J" uniqKey="Riva J" first="John J" last="Riva">John J. Riva</name><name sortKey="Roldan, Yetiani" sort="Roldan, Yetiani" uniqKey="Roldan Y" first="Yetiani" last="Roldán">Yetiani Roldán</name><name sortKey="Schunemann, Holger J" sort="Schunemann, Holger J" uniqKey="Schunemann H" first="Holger J" last="Schünemann">Holger J. 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