The oppD Gene and Putative Peptidase Genes May Be Required for Virulence in Mycoplasma gallisepticum.
Identifieur interne : 004538 ( Ncbi/Merge ); précédent : 004537; suivant : 004539The oppD Gene and Putative Peptidase Genes May Be Required for Virulence in Mycoplasma gallisepticum.
Auteurs : Chi-Wen Tseng [Australie] ; Chien-Ju Chiu [Australie] ; Anna Kanci [Australie] ; Christine Citti [France] ; Renate Rosengarten [Autriche] ; Glenn F. Browning [Australie] ; Philip F. Markham [Australie]Source :
- Infection and immunity [ 1098-5522 ] ; 2017.
Descripteurs français
- KwdFr :
- Animaux, Facteurs de virulence (génétique), Infections à Mycoplasma (génétique), Infections à Mycoplasma (microbiologie), Maladies de la volaille (génétique), Maladies de la volaille (microbiologie), Mutagenèse par insertion (génétique), Mycoplasma gallisepticum (génétique), Mycoplasma gallisepticum (pathogénicité), Poulets (microbiologie), Protéines bactériennes (génétique), Protéines bactériennes (métabolisme), Virulence (génétique).
- MESH :
- génétique : Facteurs de virulence, Infections à Mycoplasma, Maladies de la volaille, Mutagenèse par insertion, Mycoplasma gallisepticum, Protéines bactériennes, Virulence.
- microbiologie : Infections à Mycoplasma, Maladies de la volaille, Poulets.
- métabolisme : Protéines bactériennes.
- pathogénicité : Mycoplasma gallisepticum.
- Animaux.
English descriptors
- KwdEn :
- Animals, Bacterial Proteins (genetics), Bacterial Proteins (metabolism), Chickens (microbiology), Mutagenesis, Insertional (genetics), Mycoplasma Infections (genetics), Mycoplasma Infections (microbiology), Mycoplasma gallisepticum (genetics), Mycoplasma gallisepticum (pathogenicity), Poultry Diseases (genetics), Poultry Diseases (microbiology), Virulence (genetics), Virulence Factors (genetics).
- MESH :
- chemical , genetics : Bacterial Proteins, Virulence Factors.
- chemical , metabolism : Bacterial Proteins.
- genetics : Mutagenesis, Insertional, Mycoplasma Infections, Mycoplasma gallisepticum, Poultry Diseases, Virulence.
- microbiology : Chickens, Mycoplasma Infections, Poultry Diseases.
- pathogenicity : Mycoplasma gallisepticum.
- Animals.
Abstract
Relatively few virulence genes have been identified in pathogenic mycoplasmas, so we used signature-tagged mutagenesis to identify mutants of the avian pathogen Mycoplasma gallisepticum with a reduced capacity to persist in vivo and compared the levels of virulence of selected mutants in experimentally infected chickens. Four mutants had insertions in one of the two incomplete oppABCDF operons, and a further three had insertions in distinct hypothetical genes, two containing peptidase motifs and one containing a member of a gene family. The three hypothetical gene mutants and the two with insertions in oppD1 were used to infect chickens, and all five were shown to have a reduced capacity to induce respiratory tract lesions. One oppD1 mutant and the MGA_1102 and MGA_1079 mutants had a greatly reduced capacity to persist in the respiratory tract and to induce systemic antibody responses against M. gallisepticum The other oppD1 mutant and the MGA_0588 mutant had less capacity than the wild type to persist in the respiratory tract but did elicit systemic antibody responses. Although M. gallisepticum carries two incomplete opp operons, one of which has been acquired by horizontal gene transfer, our results suggest that one of the copies of oppD may be required for full expression of virulence. We have also shown that three hypothetical genes, two of which encode putative peptidases, may be required for full expression of virulence in M. gallisepticum. None of these genes has previously been shown to influence virulence in pathogenic mycoplasmas.
DOI: 10.1128/IAI.00023-17
PubMed: 28348054
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pubmed:28348054Le document en format XML
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Markham</name><affiliation wicri:level="4"><nlm:affiliation>Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria</wicri:regionArea><orgName type="university">Université de Melbourne</orgName><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author></analytic><series><title level="j">Infection and immunity</title><idno type="eISSN">1098-5522</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Bacterial Proteins (genetics)</term><term>Bacterial Proteins (metabolism)</term><term>Chickens (microbiology)</term><term>Mutagenesis, Insertional (genetics)</term><term>Mycoplasma Infections (genetics)</term><term>Mycoplasma Infections (microbiology)</term><term>Mycoplasma gallisepticum (genetics)</term><term>Mycoplasma gallisepticum (pathogenicity)</term><term>Poultry Diseases (genetics)</term><term>Poultry Diseases (microbiology)</term><term>Virulence (genetics)</term><term>Virulence Factors (genetics)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Facteurs de virulence (génétique)</term><term>Infections à Mycoplasma (génétique)</term><term>Infections à Mycoplasma (microbiologie)</term><term>Maladies de la volaille (génétique)</term><term>Maladies de la volaille (microbiologie)</term><term>Mutagenèse par insertion (génétique)</term><term>Mycoplasma gallisepticum (génétique)</term><term>Mycoplasma gallisepticum (pathogénicité)</term><term>Poulets (microbiologie)</term><term>Protéines bactériennes (génétique)</term><term>Protéines bactériennes (métabolisme)</term><term>Virulence (génétique)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Bacterial Proteins</term><term>Virulence Factors</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Bacterial Proteins</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Mutagenesis, Insertional</term><term>Mycoplasma Infections</term><term>Mycoplasma gallisepticum</term><term>Poultry Diseases</term><term>Virulence</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Facteurs de virulence</term><term>Infections à Mycoplasma</term><term>Maladies de la volaille</term><term>Mutagenèse par insertion</term><term>Mycoplasma gallisepticum</term><term>Protéines bactériennes</term><term>Virulence</term></keywords><keywords scheme="MESH" qualifier="microbiologie" xml:lang="fr"><term>Infections à Mycoplasma</term><term>Maladies de la volaille</term><term>Poulets</term></keywords><keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Chickens</term><term>Mycoplasma Infections</term><term>Poultry Diseases</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Protéines bactériennes</term></keywords><keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>Mycoplasma gallisepticum</term></keywords><keywords scheme="MESH" qualifier="pathogénicité" xml:lang="fr"><term>Mycoplasma gallisepticum</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Relatively few virulence genes have been identified in pathogenic mycoplasmas, so we used signature-tagged mutagenesis to identify mutants of the avian pathogen Mycoplasma gallisepticum with a reduced capacity to persist in vivo and compared the levels of virulence of selected mutants in experimentally infected chickens. Four mutants had insertions in one of the two incomplete oppABCDF operons, and a further three had insertions in distinct hypothetical genes, two containing peptidase motifs and one containing a member of a gene family. The three hypothetical gene mutants and the two with insertions in oppD1 were used to infect chickens, and all five were shown to have a reduced capacity to induce respiratory tract lesions. One oppD1 mutant and the MGA_1102 and MGA_1079 mutants had a greatly reduced capacity to persist in the respiratory tract and to induce systemic antibody responses against M. gallisepticum The other oppD1 mutant and the MGA_0588 mutant had less capacity than the wild type to persist in the respiratory tract but did elicit systemic antibody responses. Although M. gallisepticum carries two incomplete opp operons, one of which has been acquired by horizontal gene transfer, our results suggest that one of the copies of oppD may be required for full expression of virulence. We have also shown that three hypothetical genes, two of which encode putative peptidases, may be required for full expression of virulence in M. gallisepticum. None of these genes has previously been shown to influence virulence in pathogenic mycoplasmas.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">28348054</PMID><DateCreated><Year>2017</Year><Month>03</Month><Day>28</Day></DateCreated><DateCompleted><Year>2017</Year><Month>07</Month><Day>31</Day></DateCompleted><DateRevised><Year>2017</Year><Month>07</Month><Day>31</Day></DateRevised><Article PubModel="Electronic-Print"><Journal><ISSN IssnType="Electronic">1098-5522</ISSN><JournalIssue CitedMedium="Internet"><Volume>85</Volume><Issue>6</Issue><PubDate><Year>2017</Year><Month>Jun</Month></PubDate></JournalIssue><Title>Infection and immunity</Title><ISOAbbreviation>Infect. Immun.</ISOAbbreviation></Journal><ArticleTitle>The oppD Gene and Putative Peptidase Genes May Be Required for Virulence in Mycoplasma gallisepticum.</ArticleTitle><ELocationID EIdType="pii" ValidYN="Y">e00023-17</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1128/IAI.00023-17</ELocationID><Abstract><AbstractText>Relatively few virulence genes have been identified in pathogenic mycoplasmas, so we used signature-tagged mutagenesis to identify mutants of the avian pathogen Mycoplasma gallisepticum with a reduced capacity to persist in vivo and compared the levels of virulence of selected mutants in experimentally infected chickens. Four mutants had insertions in one of the two incomplete oppABCDF operons, and a further three had insertions in distinct hypothetical genes, two containing peptidase motifs and one containing a member of a gene family. The three hypothetical gene mutants and the two with insertions in oppD1 were used to infect chickens, and all five were shown to have a reduced capacity to induce respiratory tract lesions. One oppD1 mutant and the MGA_1102 and MGA_1079 mutants had a greatly reduced capacity to persist in the respiratory tract and to induce systemic antibody responses against M. gallisepticum The other oppD1 mutant and the MGA_0588 mutant had less capacity than the wild type to persist in the respiratory tract but did elicit systemic antibody responses. Although M. gallisepticum carries two incomplete opp operons, one of which has been acquired by horizontal gene transfer, our results suggest that one of the copies of oppD may be required for full expression of virulence. We have also shown that three hypothetical genes, two of which encode putative peptidases, may be required for full expression of virulence in M. gallisepticum. None of these genes has previously been shown to influence virulence in pathogenic mycoplasmas.</AbstractText><CopyrightInformation>Copyright © 2017 American Society for Microbiology.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Tseng</LastName><ForeName>Chi-Wen</ForeName><Initials>CW</Initials><AffiliationInfo><Affiliation>Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chiu</LastName><ForeName>Chien-Ju</ForeName><Initials>CJ</Initials><AffiliationInfo><Affiliation>Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kanci</LastName><ForeName>Anna</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Citti</LastName><ForeName>Christine</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>INRA, ENVT, UMR 1225, Toulouse, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Institute of Bacteriology, Mycology and Hygiene, University of Veterinary Medicine, Vienna, Vienna, Austria.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rosengarten</LastName><ForeName>Renate</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Institute of Bacteriology, Mycology and Hygiene, University of Veterinary Medicine, Vienna, Vienna, Austria.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Browning</LastName><ForeName>Glenn F</ForeName><Initials>GF</Initials><Identifier Source="ORCID">http://orcid.org/0000-0002-0903-2469</Identifier><AffiliationInfo><Affiliation>Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria, Australia glenfb@unimelb.edu.au.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Markham</LastName><ForeName>Philip F</ForeName><Initials>PF</Initials><AffiliationInfo><Affiliation>Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria, Australia.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>05</Month><Day>23</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Infect Immun</MedlineTA><NlmUniqueID>0246127</NlmUniqueID><ISSNLinking>0019-9567</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D001426">Bacterial Proteins</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D037521">Virulence Factors</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Infect Immun. 2014 Nov;82(11):4758-66</RefSource><PMID Version="1">25156736</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>PLoS One. 2012;7(5):e38239</RefSource><PMID Version="1">22693604</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nucleic Acids Res. 1996 Nov 15;24(22):4420-49</RefSource><PMID Version="1">8948633</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Microbiology. 2003 Jan;149(Pt 1):167-76</RefSource><PMID Version="1">12576590</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Curr Opin Struct Biol. 2002 Dec;12(6):754-60</RefSource><PMID Version="1">12504680</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>PLoS Genet. 2007 May 18;3(5):e75</RefSource><PMID Version="1">17511520</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Avian Dis. 1982 Jul-Sep;26(3):487-95</RefSource><PMID Version="1">7150143</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Avian Dis. 1986 Jan-Mar;30(1):160-8</RefSource><PMID Version="1">3729859</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Microbiology. 2003 Sep;149(Pt 9):2307-16</RefSource><PMID Version="1">12949158</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Infect Immun. 2003 Mar;71(3):1265-73</RefSource><PMID Version="1">12595441</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Biochim Biophys Acta. 1999 Dec 6;1461(2):177-200</RefSource><PMID Version="1">10581355</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Bioenerg Biomembr. 2005 Dec;37(6):349-57</RefSource><PMID Version="1">16691464</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nihon Juigaku Zasshi. 1987 Aug;49(4):621-9</RefSource><PMID Version="1">3626242</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Avian Dis. 1996 Jul-Sep;40(3):654-60</RefSource><PMID Version="1">8883797</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Infect Immun. 2011 Feb;79(2):982-3</RefSource><PMID Version="1">21134966</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Microbiology. 2013 Jul;159(Pt 7):1459-70</RefSource><PMID Version="1">23657682</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Avian Dis. 1981 Oct-Dec;25(4):1005-18</RefSource><PMID Version="1">7337604</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Annu Rev Cell Biol. 1992;8:67-113</RefSource><PMID Version="1">1282354</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Gene. 1989 Sep 30;81(2):361-7</RefSource><PMID Version="1">2553542</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Gene. 1993 Dec 31;137(2):217-22</RefSource><PMID Version="1">8299950</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Biomed Res Int. 2014;2014:489782</RefSource><PMID Version="1">24895581</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Infect Immun. 2013 Sep;81(9):3220-6</RefSource><PMID Version="1">23798535</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell Mol Life Sci. 2004 Mar;61(6):682-99</RefSource><PMID Version="1">15052411</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Science. 1995 Oct 20;270(5235):397-403</RefSource><PMID Version="1">7569993</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Bacteriol. 1999 Aug;181(16):4873-8</RefSource><PMID Version="1">10438757</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Plasmid. 1993 Sep;30(2):170-5</RefSource><PMID Version="1">8234492</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Brief Bioinform. 2004 Jun;5(2):150-63</RefSource><PMID Version="1">15260895</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Infect Immun. 2004 Dec;72(12):6757-63</RefSource><PMID Version="1">15557595</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Microbiology. 2000 May;146 ( Pt 5):1223-9</RefSource><PMID Version="1">10832650</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nucleic Acids Res. 1994 Nov 11;22(22):4673-80</RefSource><PMID Version="1">7984417</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Science. 1995 Jul 21;269(5222):400-3</RefSource><PMID Version="1">7618105</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Aust Vet J. 1989 Mar;66(3):65-72</RefSource><PMID Version="1">2712773</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Infect Immun. 2006 Feb;74(2):931-9</RefSource><PMID Version="1">16428737</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Infect Immun. 2010 Aug;78(8):3475-83</RefSource><PMID Version="1">20515935</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001426" MajorTopicYN="N">Bacterial Proteins</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002645" MajorTopicYN="N">Chickens</DescriptorName><QualifierName UI="Q000382" MajorTopicYN="Y">microbiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016254" MajorTopicYN="N">Mutagenesis, Insertional</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D009175" MajorTopicYN="N">Mycoplasma Infections</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D045686" MajorTopicYN="N">Mycoplasma gallisepticum</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName><QualifierName UI="Q000472" MajorTopicYN="Y">pathogenicity</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011201" MajorTopicYN="N">Poultry Diseases</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000382" MajorTopicYN="Y">microbiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014774" MajorTopicYN="N">Virulence</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D037521" MajorTopicYN="N">Virulence Factors</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Mycoplasma gallisepticum</Keyword><Keyword MajorTopicYN="N">oppD</Keyword><Keyword MajorTopicYN="N">virulence</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2017</Year><Month>01</Month><Day>09</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2017</Year><Month>03</Month><Day>19</Day></PubMedPubDate><PubMedPubDate PubStatus="pmc-release"><Year>2017</Year><Month>11</Month><Day>23</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>3</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>8</Month><Day>2</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>3</Month><Day>29</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28348054</ArticleId><ArticleId IdType="pii">IAI.00023-17</ArticleId><ArticleId IdType="doi">10.1128/IAI.00023-17</ArticleId><ArticleId IdType="pmc">PMC5442611</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Australie</li><li>Autriche</li><li>France</li></country><region><li>Midi-Pyrénées</li><li>Occitanie (région administrative)</li><li>Victoria (État)</li><li>Vienne (Autriche)</li></region><settlement><li>Melbourne</li><li>Toulouse</li><li>Vienne (Autriche)</li></settlement><orgName><li>Université de Melbourne</li></orgName></list><tree><country name="Australie"><region name="Victoria (État)"><name sortKey="Tseng, Chi Wen" sort="Tseng, Chi Wen" uniqKey="Tseng C" first="Chi-Wen" last="Tseng">Chi-Wen Tseng</name></region><name sortKey="Browning, Glenn F" sort="Browning, Glenn F" uniqKey="Browning G" first="Glenn F" last="Browning">Glenn F. Browning</name><name sortKey="Chiu, Chien Ju" sort="Chiu, Chien Ju" uniqKey="Chiu C" first="Chien-Ju" last="Chiu">Chien-Ju Chiu</name><name sortKey="Kanci, Anna" sort="Kanci, Anna" uniqKey="Kanci A" first="Anna" last="Kanci">Anna Kanci</name><name sortKey="Markham, Philip F" sort="Markham, Philip F" uniqKey="Markham P" first="Philip F" last="Markham">Philip F. Markham</name></country><country name="France"><region name="Occitanie (région administrative)"><name sortKey="Citti, Christine" sort="Citti, Christine" uniqKey="Citti C" first="Christine" last="Citti">Christine Citti</name></region></country><country name="Autriche"><region name="Vienne (Autriche)"><name sortKey="Rosengarten, Renate" sort="Rosengarten, Renate" uniqKey="Rosengarten R" first="Renate" last="Rosengarten">Renate Rosengarten</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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