Validation of criteria for the definition of transient lower esophageal sphincter relaxations using high-resolution manometry.
Identifieur interne : 003922 ( Ncbi/Merge ); précédent : 003921; suivant : 003923Validation of criteria for the definition of transient lower esophageal sphincter relaxations using high-resolution manometry.
Auteurs : S. Roman [France] ; R. Holloway [Australie] ; J. Keller [Allemagne] ; F. Herbella [Brésil] ; F. Zerbib [France] ; Y. Xiao [République populaire de Chine] ; L. Bernard [France] ; A J Bredenoord [Pays-Bas] ; S. Bruley Des Varannes [France] ; M. Chen [Australie] ; M. Fox [Suisse] ; P J Kahrilas [États-Unis] ; R K Mittal [États-Unis] ; R. Penagini [Italie] ; E. Savarino [Italie] ; D. Sifrim [Royaume-Uni] ; J. Wu [République populaire de Chine] ; E. Decullier [France] ; J E Pandolfino [États-Unis] ; F. Mion [France]Source :
- Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society [ 1365-2982 ] ; 2017.
Abstract
Criteria for transient lower esophageal sphincter relaxations (TLESRs) are well-defined for Dentsleeve manometry. As high-resolution manometry (HRM) is now the gold standard to assess esophageal motility, our aim was to propose a consensus definition of TLESRs using HRM.
DOI: 10.1111/nmo.12920
PubMed: 27477826
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Holloway</name><affiliation wicri:level="1"><nlm:affiliation>Gastroenterology and Hepatology, Royal Adelaid Hospital, Adelaide, SA, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Gastroenterology and Hepatology, Royal Adelaid Hospital, Adelaide, SA</wicri:regionArea><wicri:noRegion>SA</wicri:noRegion></affiliation></author><author><name sortKey="Keller, J" sort="Keller, J" uniqKey="Keller J" first="J" last="Keller">J. 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Bernard</name><affiliation wicri:level="3"><nlm:affiliation>Hospices Civils de Lyon, Pôle Information Médicale Evaluation Recherche, Unité de recherche clinique, Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Hospices Civils de Lyon, Pôle Information Médicale Evaluation Recherche, Unité de recherche clinique, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Bredenoord, A J" sort="Bredenoord, A J" uniqKey="Bredenoord A" first="A J" last="Bredenoord">A J Bredenoord</name><affiliation wicri:level="3"><nlm:affiliation>Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Gastroenterology and Hepatology, Academic Medical Center, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Bruley Des Varannes, S" sort="Bruley Des Varannes, S" uniqKey="Bruley Des Varannes S" first="S" last="Bruley Des Varannes">S. Bruley Des Varannes</name><affiliation wicri:level="3"><nlm:affiliation>Institut des Maladies de l'Appareil Digestif, CHU Nantes and Nantes University, Nantes, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Institut des Maladies de l'Appareil Digestif, CHU Nantes and Nantes University, Nantes</wicri:regionArea><placeName><region type="region">Pays de la Loire</region><region type="old region">Pays de la Loire</region><settlement type="city">Nantes</settlement></placeName></affiliation></author><author><name sortKey="Chen, M" sort="Chen, M" uniqKey="Chen M" first="M" last="Chen">M. Chen</name><affiliation wicri:level="1"><nlm:affiliation>Gastroenterology and Hepatology, Royal Adelaid Hospital, Adelaide, SA, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Gastroenterology and Hepatology, Royal Adelaid Hospital, Adelaide, SA</wicri:regionArea><wicri:noRegion>SA</wicri:noRegion></affiliation></author><author><name sortKey="Fox, M" sort="Fox, M" uniqKey="Fox M" first="M" last="Fox">M. Fox</name><affiliation wicri:level="1"><nlm:affiliation>iDigest Clinic and Laboratory for Disorders of GI Motility and Function, Division of Gastroenterology, University Hospital Zurich, Zurich, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>iDigest Clinic and Laboratory for Disorders of GI Motility and Function, Division of Gastroenterology, University Hospital Zurich, Zurich</wicri:regionArea><wicri:noRegion>Zurich</wicri:noRegion></affiliation></author><author><name sortKey="Kahrilas, P J" sort="Kahrilas, P J" uniqKey="Kahrilas P" first="P J" last="Kahrilas">P J Kahrilas</name><affiliation wicri:level="2"><nlm:affiliation>Division of Gasotrenterology, Department of Medicine, Northwestern University, Chicago, IL, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Gasotrenterology, Department of Medicine, Northwestern University, Chicago, IL</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Mittal, R K" sort="Mittal, R K" uniqKey="Mittal R" first="R K" last="Mittal">R K Mittal</name><affiliation wicri:level="2"><nlm:affiliation>Division of Gastroenterology, Department of Medicine, University of California San Diego, San Diego, CA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Gastroenterology, Department of Medicine, University of California San Diego, San Diego, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Penagini, R" sort="Penagini, R" uniqKey="Penagini R" first="R" last="Penagini">R. Penagini</name><affiliation wicri:level="3"><nlm:affiliation>Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Savarino, E" sort="Savarino, E" uniqKey="Savarino E" first="E" last="Savarino">E. Savarino</name><affiliation wicri:level="1"><nlm:affiliation>Division of Gastroenterology, Department of Surgical, Oncological and Gastroenterological Sciences, University of Padua, Padua, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Gastroenterology, Department of Surgical, Oncological and Gastroenterological Sciences, University of Padua, Padua</wicri:regionArea><wicri:noRegion>Padua</wicri:noRegion></affiliation></author><author><name sortKey="Sifrim, D" sort="Sifrim, D" uniqKey="Sifrim D" first="D" last="Sifrim">D. 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Wu</name><affiliation wicri:level="4"><nlm:affiliation>Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author><author><name sortKey="Decullier, E" sort="Decullier, E" uniqKey="Decullier E" first="E" last="Decullier">E. Decullier</name><affiliation wicri:level="3"><nlm:affiliation>Hospices Civils de Lyon, Pôle Information Médicale Evaluation Recherche, Unité de recherche clinique, Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Hospices Civils de Lyon, Pôle Information Médicale Evaluation Recherche, Unité de recherche clinique, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Pandolfino, J E" sort="Pandolfino, J E" uniqKey="Pandolfino J" first="J E" last="Pandolfino">J E Pandolfino</name><affiliation wicri:level="2"><nlm:affiliation>Division of Gasotrenterology, Department of Medicine, Northwestern University, Chicago, IL, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Gasotrenterology, Department of Medicine, Northwestern University, Chicago, IL</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Mion, F" sort="Mion, F" uniqKey="Mion F" first="F" last="Mion">F. Mion</name><affiliation wicri:level="3"><nlm:affiliation>Digestive Physiology, Hospices Civils de Lyon, and Lyon I University, Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Digestive Physiology, Hospices Civils de Lyon, and Lyon I University, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:27477826</idno><idno type="pmid">27477826</idno><idno type="doi">10.1111/nmo.12920</idno><idno type="wicri:Area/PubMed/Corpus">001122</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001122</idno><idno type="wicri:Area/PubMed/Curation">001119</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001119</idno><idno type="wicri:Area/PubMed/Checkpoint">001119</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001119</idno><idno type="wicri:Area/Ncbi/Merge">003922</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Validation of criteria for the definition of transient lower esophageal sphincter relaxations using high-resolution manometry.</title><author><name sortKey="Roman, S" sort="Roman, S" uniqKey="Roman S" first="S" last="Roman">S. Roman</name><affiliation wicri:level="3"><nlm:affiliation>Digestive Physiology, Hospices Civils de Lyon, and Lyon I University, Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Digestive Physiology, Hospices Civils de Lyon, and Lyon I University, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Holloway, R" sort="Holloway, R" uniqKey="Holloway R" first="R" last="Holloway">R. Holloway</name><affiliation wicri:level="1"><nlm:affiliation>Gastroenterology and Hepatology, Royal Adelaid Hospital, Adelaide, SA, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Gastroenterology and Hepatology, Royal Adelaid Hospital, Adelaide, SA</wicri:regionArea><wicri:noRegion>SA</wicri:noRegion></affiliation></author><author><name sortKey="Keller, J" sort="Keller, J" uniqKey="Keller J" first="J" last="Keller">J. Keller</name><affiliation wicri:level="3"><nlm:affiliation>Department of Internal Medicine, Israelitic Hospital, University of Hamburg, Hamburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Internal Medicine, Israelitic Hospital, University of Hamburg, Hamburg</wicri:regionArea><placeName><settlement type="city">Hambourg</settlement><region type="land" nuts="2">Hambourg</region></placeName></affiliation></author><author><name sortKey="Herbella, F" sort="Herbella, F" uniqKey="Herbella F" first="F" last="Herbella">F. Herbella</name><affiliation wicri:level="3"><nlm:affiliation>Department of Surgery, Escola Paulista de Medicina, Federal University of Sao Paulo, Sao Paulo, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Surgery, Escola Paulista de Medicina, Federal University of Sao Paulo, Sao Paulo</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region></placeName></affiliation></author><author><name sortKey="Zerbib, F" sort="Zerbib, F" uniqKey="Zerbib F" first="F" last="Zerbib">F. Zerbib</name><affiliation wicri:level="3"><nlm:affiliation>Gastroenterology, CHU Bordeaux and Bordeaux II University, Bordeaux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Gastroenterology, CHU Bordeaux and Bordeaux II University, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Xiao, Y" sort="Xiao, Y" uniqKey="Xiao Y" first="Y" last="Xiao">Y. Xiao</name><affiliation wicri:level="3"><nlm:affiliation>Department of Gastroenterology and Hepatology, The First affiliated Hospital, Sen Yat-sen University, Guangzhou, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Gastroenterology and Hepatology, The First affiliated Hospital, Sen Yat-sen University, Guangzhou</wicri:regionArea><placeName><settlement type="city">Jiangmen</settlement><region type="province">Guangdong</region></placeName></affiliation></author><author><name sortKey="Bernard, L" sort="Bernard, L" uniqKey="Bernard L" first="L" last="Bernard">L. Bernard</name><affiliation wicri:level="3"><nlm:affiliation>Hospices Civils de Lyon, Pôle Information Médicale Evaluation Recherche, Unité de recherche clinique, Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Hospices Civils de Lyon, Pôle Information Médicale Evaluation Recherche, Unité de recherche clinique, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Bredenoord, A J" sort="Bredenoord, A J" uniqKey="Bredenoord A" first="A J" last="Bredenoord">A J Bredenoord</name><affiliation wicri:level="3"><nlm:affiliation>Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Gastroenterology and Hepatology, Academic Medical Center, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Bruley Des Varannes, S" sort="Bruley Des Varannes, S" uniqKey="Bruley Des Varannes S" first="S" last="Bruley Des Varannes">S. Bruley Des Varannes</name><affiliation wicri:level="3"><nlm:affiliation>Institut des Maladies de l'Appareil Digestif, CHU Nantes and Nantes University, Nantes, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Institut des Maladies de l'Appareil Digestif, CHU Nantes and Nantes University, Nantes</wicri:regionArea><placeName><region type="region">Pays de la Loire</region><region type="old region">Pays de la Loire</region><settlement type="city">Nantes</settlement></placeName></affiliation></author><author><name sortKey="Chen, M" sort="Chen, M" uniqKey="Chen M" first="M" last="Chen">M. Chen</name><affiliation wicri:level="1"><nlm:affiliation>Gastroenterology and Hepatology, Royal Adelaid Hospital, Adelaide, SA, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Gastroenterology and Hepatology, Royal Adelaid Hospital, Adelaide, SA</wicri:regionArea><wicri:noRegion>SA</wicri:noRegion></affiliation></author><author><name sortKey="Fox, M" sort="Fox, M" uniqKey="Fox M" first="M" last="Fox">M. Fox</name><affiliation wicri:level="1"><nlm:affiliation>iDigest Clinic and Laboratory for Disorders of GI Motility and Function, Division of Gastroenterology, University Hospital Zurich, Zurich, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>iDigest Clinic and Laboratory for Disorders of GI Motility and Function, Division of Gastroenterology, University Hospital Zurich, Zurich</wicri:regionArea><wicri:noRegion>Zurich</wicri:noRegion></affiliation></author><author><name sortKey="Kahrilas, P J" sort="Kahrilas, P J" uniqKey="Kahrilas P" first="P J" last="Kahrilas">P J Kahrilas</name><affiliation wicri:level="2"><nlm:affiliation>Division of Gasotrenterology, Department of Medicine, Northwestern University, Chicago, IL, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Gasotrenterology, Department of Medicine, Northwestern University, Chicago, IL</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Mittal, R K" sort="Mittal, R K" uniqKey="Mittal R" first="R K" last="Mittal">R K Mittal</name><affiliation wicri:level="2"><nlm:affiliation>Division of Gastroenterology, Department of Medicine, University of California San Diego, San Diego, CA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Gastroenterology, Department of Medicine, University of California San Diego, San Diego, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Penagini, R" sort="Penagini, R" uniqKey="Penagini R" first="R" last="Penagini">R. Penagini</name><affiliation wicri:level="3"><nlm:affiliation>Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Savarino, E" sort="Savarino, E" uniqKey="Savarino E" first="E" last="Savarino">E. Savarino</name><affiliation wicri:level="1"><nlm:affiliation>Division of Gastroenterology, Department of Surgical, Oncological and Gastroenterological Sciences, University of Padua, Padua, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Gastroenterology, Department of Surgical, Oncological and Gastroenterological Sciences, University of Padua, Padua</wicri:regionArea><wicri:noRegion>Padua</wicri:noRegion></affiliation></author><author><name sortKey="Sifrim, D" sort="Sifrim, D" uniqKey="Sifrim D" first="D" last="Sifrim">D. Sifrim</name><affiliation wicri:level="3"><nlm:affiliation>Center for Digestive Diseases, Bart's and the London School and Dentistry, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Center for Digestive Diseases, Bart's and the London School and Dentistry, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Wu, J" sort="Wu, J" uniqKey="Wu J" first="J" last="Wu">J. Wu</name><affiliation wicri:level="4"><nlm:affiliation>Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author><author><name sortKey="Decullier, E" sort="Decullier, E" uniqKey="Decullier E" first="E" last="Decullier">E. Decullier</name><affiliation wicri:level="3"><nlm:affiliation>Hospices Civils de Lyon, Pôle Information Médicale Evaluation Recherche, Unité de recherche clinique, Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Hospices Civils de Lyon, Pôle Information Médicale Evaluation Recherche, Unité de recherche clinique, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Pandolfino, J E" sort="Pandolfino, J E" uniqKey="Pandolfino J" first="J E" last="Pandolfino">J E Pandolfino</name><affiliation wicri:level="2"><nlm:affiliation>Division of Gasotrenterology, Department of Medicine, Northwestern University, Chicago, IL, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Gasotrenterology, Department of Medicine, Northwestern University, Chicago, IL</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Mion, F" sort="Mion, F" uniqKey="Mion F" first="F" last="Mion">F. Mion</name><affiliation wicri:level="3"><nlm:affiliation>Digestive Physiology, Hospices Civils de Lyon, and Lyon I University, Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Digestive Physiology, Hospices Civils de Lyon, and Lyon I University, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author></analytic><series><title level="j">Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society</title><idno type="eISSN">1365-2982</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Criteria for transient lower esophageal sphincter relaxations (TLESRs) are well-defined for Dentsleeve manometry. As high-resolution manometry (HRM) is now the gold standard to assess esophageal motility, our aim was to propose a consensus definition of TLESRs using HRM.</div></front></TEI><pubmed><MedlineCitation Status="In-Process" Owner="NLM"><PMID Version="1">27477826</PMID><DateCreated><Year>2016</Year><Month>08</Month><Day>01</Day></DateCreated><DateRevised><Year>2017</Year><Month>01</Month><Day>29</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1365-2982</ISSN><JournalIssue CitedMedium="Internet"><Volume>29</Volume><Issue>2</Issue><PubDate><Year>2017</Year><Month>Feb</Month></PubDate></JournalIssue><Title>Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society</Title><ISOAbbreviation>Neurogastroenterol. Motil.</ISOAbbreviation></Journal><ArticleTitle>Validation of criteria for the definition of transient lower esophageal sphincter relaxations using high-resolution manometry.</ArticleTitle><ELocationID EIdType="doi" ValidYN="Y">10.1111/nmo.12920</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Criteria for transient lower esophageal sphincter relaxations (TLESRs) are well-defined for Dentsleeve manometry. As high-resolution manometry (HRM) is now the gold standard to assess esophageal motility, our aim was to propose a consensus definition of TLESRs using HRM.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Postprandial esophageal HRM combined with impedance was performed in 10 patients with gastroesophageal reflux disease. Transient lower esophageal sphincter relaxations identification was performed by 17 experts using a Delphi process. Four investigators then characterized TLESR candidates that achieved 100% agreement (TLESR events) and those that achieved less than 25% agreement (non-events) after the third round. Logistic regression and decision tree analysis were used to define optimal diagnostic criteria.</AbstractText><AbstractText Label="KEY RESULTS" NlmCategory="RESULTS">All diagnostic criteria were more frequently encountered in the 57 TLESR events than in the 52 non-events. Crural diaphragm (CD) inhibition and LES relaxation duration >10 seconds had the highest predictive value to identify TLESR. Based on decision tree analysis, reflux on impedance, esophageal shortening, common cavity, upper esophageal sphincter relaxation without swallow and secondary peristalsis were alternate diagnostic criteria.</AbstractText><AbstractText Label="CONCLUSION & INFERENCES" NlmCategory="CONCLUSIONS">Using HRM, TLESR might be defined as LES relaxation occurring in absence of swallowing, lasting more than 10 seconds and associated with CD inhibition.</AbstractText><CopyrightInformation>© 2016 John Wiley & Sons Ltd.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Roman</LastName><ForeName>S</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Digestive Physiology, Hospices Civils de Lyon, and Lyon I University, Lyon, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Inserm U1032, LabTAU, Lyon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Holloway</LastName><ForeName>R</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Gastroenterology and Hepatology, Royal Adelaid Hospital, Adelaide, SA, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Keller</LastName><ForeName>J</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, Israelitic Hospital, University of Hamburg, Hamburg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Herbella</LastName><ForeName>F</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Department of Surgery, Escola Paulista de Medicina, Federal University of Sao Paulo, Sao Paulo, Brazil.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zerbib</LastName><ForeName>F</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Gastroenterology, CHU Bordeaux and Bordeaux II University, Bordeaux, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Xiao</LastName><ForeName>Y</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Department of Gastroenterology and Hepatology, The First affiliated Hospital, Sen Yat-sen University, Guangzhou, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bernard</LastName><ForeName>L</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Hospices Civils de Lyon, Pôle Information Médicale Evaluation Recherche, Unité de recherche clinique, Lyon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bredenoord</LastName><ForeName>A J</ForeName><Initials>AJ</Initials><AffiliationInfo><Affiliation>Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bruley des Varannes</LastName><ForeName>S</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Institut des Maladies de l'Appareil Digestif, CHU Nantes and Nantes University, Nantes, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chen</LastName><ForeName>M</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Gastroenterology and Hepatology, Royal Adelaid Hospital, Adelaide, SA, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fox</LastName><ForeName>M</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>iDigest Clinic and Laboratory for Disorders of GI Motility and Function, Division of Gastroenterology, University Hospital Zurich, Zurich, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kahrilas</LastName><ForeName>P J</ForeName><Initials>PJ</Initials><AffiliationInfo><Affiliation>Division of Gasotrenterology, Department of Medicine, Northwestern University, Chicago, IL, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mittal</LastName><ForeName>R K</ForeName><Initials>RK</Initials><AffiliationInfo><Affiliation>Division of Gastroenterology, Department of Medicine, University of California San Diego, San Diego, CA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Penagini</LastName><ForeName>R</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Pathophysiology and Transplantation, Università degli Studi, Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Savarino</LastName><ForeName>E</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Division of Gastroenterology, Department of Surgical, Oncological and Gastroenterological Sciences, University of Padua, Padua, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sifrim</LastName><ForeName>D</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Center for Digestive Diseases, Bart's and the London School and Dentistry, London, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wu</LastName><ForeName>J</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Decullier</LastName><ForeName>E</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Hospices Civils de Lyon, Pôle Information Médicale Evaluation Recherche, Unité de recherche clinique, Lyon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pandolfino</LastName><ForeName>J E</ForeName><Initials>JE</Initials><AffiliationInfo><Affiliation>Division of Gasotrenterology, Department of Medicine, Northwestern University, Chicago, IL, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mion</LastName><ForeName>F</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Digestive Physiology, Hospices Civils de Lyon, and Lyon I University, Lyon, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Inserm U1032, LabTAU, Lyon, France.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2016</Year><Month>07</Month><Day>31</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Neurogastroenterol Motil</MedlineTA><NlmUniqueID>9432572</NlmUniqueID><ISSNLinking>1350-1925</ISSNLinking></MedlineJournalInfo><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">consensus</Keyword><Keyword MajorTopicYN="N">gastroesophageal reflux disease</Keyword><Keyword MajorTopicYN="N">high-resolution manometry</Keyword><Keyword MajorTopicYN="N">transient lower esophageal sphincter relaxation</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year><Month>05</Month><Day>03</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2016</Year><Month>07</Month><Day>14</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2016</Year><Month>8</Month><Day>2</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2016</Year><Month>8</Month><Day>2</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2016</Year><Month>8</Month><Day>2</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">27477826</ArticleId><ArticleId IdType="doi">10.1111/nmo.12920</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Brésil</li><li>France</li><li>Italie</li><li>Pays-Bas</li><li>Royaume-Uni</li><li>République populaire de Chine</li><li>Suisse</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Aquitaine</li><li>Auvergne-Rhône-Alpes</li><li>Californie</li><li>Grand Londres</li><li>Guangdong</li><li>Hambourg</li><li>Hollande-Septentrionale</li><li>Illinois</li><li>Lombardie</li><li>Nouvelle-Aquitaine</li><li>Pays de la Loire</li><li>Rhône-Alpes</li><li>État de São Paulo</li></region><settlement><li>Amsterdam</li><li>Bordeaux</li><li>Hambourg</li><li>Jiangmen</li><li>Londres</li><li>Lyon</li><li>Milan</li><li>Nantes</li><li>Sha Tin</li><li>São Paulo</li></settlement><orgName><li>Université chinoise de Hong Kong</li></orgName></list><tree><country name="France"><region name="Auvergne-Rhône-Alpes"><name sortKey="Roman, S" sort="Roman, S" uniqKey="Roman S" first="S" last="Roman">S. Roman</name></region><name sortKey="Bernard, L" sort="Bernard, L" uniqKey="Bernard L" first="L" last="Bernard">L. Bernard</name><name sortKey="Bruley Des Varannes, S" sort="Bruley Des Varannes, S" uniqKey="Bruley Des Varannes S" first="S" last="Bruley Des Varannes">S. Bruley Des Varannes</name><name sortKey="Decullier, E" sort="Decullier, E" uniqKey="Decullier E" first="E" last="Decullier">E. Decullier</name><name sortKey="Mion, F" sort="Mion, F" uniqKey="Mion F" first="F" last="Mion">F. Mion</name><name sortKey="Zerbib, F" sort="Zerbib, F" uniqKey="Zerbib F" first="F" last="Zerbib">F. Zerbib</name></country><country name="Australie"><noRegion><name sortKey="Holloway, R" sort="Holloway, R" uniqKey="Holloway R" first="R" last="Holloway">R. Holloway</name></noRegion><name sortKey="Chen, M" sort="Chen, M" uniqKey="Chen M" first="M" last="Chen">M. Chen</name></country><country name="Allemagne"><region name="Hambourg"><name sortKey="Keller, J" sort="Keller, J" uniqKey="Keller J" first="J" last="Keller">J. Keller</name></region></country><country name="Brésil"><region name="État de São Paulo"><name sortKey="Herbella, F" sort="Herbella, F" uniqKey="Herbella F" first="F" last="Herbella">F. Herbella</name></region></country><country name="République populaire de Chine"><region name="Guangdong"><name sortKey="Xiao, Y" sort="Xiao, Y" uniqKey="Xiao Y" first="Y" last="Xiao">Y. Xiao</name></region><name sortKey="Wu, J" sort="Wu, J" uniqKey="Wu J" first="J" last="Wu">J. Wu</name></country><country name="Pays-Bas"><region name="Hollande-Septentrionale"><name sortKey="Bredenoord, A J" sort="Bredenoord, A J" uniqKey="Bredenoord A" first="A J" last="Bredenoord">A J Bredenoord</name></region></country><country name="Suisse"><noRegion><name sortKey="Fox, M" sort="Fox, M" uniqKey="Fox M" first="M" last="Fox">M. 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