Effect of sow vaccination against porcine circovirus type 2 (PCV2) on virological profiles in herds with or without PCV2 systemic disease
Identifieur interne : 003621 ( Ncbi/Merge ); précédent : 003620; suivant : 003622Effect of sow vaccination against porcine circovirus type 2 (PCV2) on virological profiles in herds with or without PCV2 systemic disease
Auteurs : Alfonso Lopez-Rodriguez ; Jeroen Dewulf ; Tom Meyns ; Rubén Del-Pozo-Sacristán ; Christine Andreoni ; Anne Goubier ; Ludivine Chapat ; Catherine Charreyre ; François Joisel ; Dominiek MaesSource :
- The Canadian Veterinary Journal [ 0008-5286 ] ; 2016.
Descripteurs français
- KwdFr :
- Animaux, Antigènes CD79 (sang), Circovirus, Femelle, Fèces (virologie), Immunité cellulaire, Infections à Circoviridae (), Infections à Circoviridae (médecine vétérinaire), Infections à Circoviridae (virologie), Maladies des porcs (), Maladies des porcs (immunologie), Maladies des porcs (virologie), Réaction de polymérisation en chaine en temps réel, Suidae, Vaccins antiviraux (administration et posologie).
- MESH :
- administration et posologie : Vaccins antiviraux.
- immunologie : Maladies des porcs.
- médecine vétérinaire : Infections à Circoviridae.
- sang : Antigènes CD79.
- virologie : Fèces, Infections à Circoviridae, Maladies des porcs.
- Animaux, Circovirus, Femelle, Immunité cellulaire, Infections à Circoviridae, Maladies des porcs, Réaction de polymérisation en chaine en temps réel, Suidae.
English descriptors
- KwdEn :
- Animals, Antigens, CD79 (blood), Circoviridae Infections (prevention & control), Circoviridae Infections (veterinary), Circoviridae Infections (virology), Circovirus, Feces (virology), Female, Immunity, Cellular, Real-Time Polymerase Chain Reaction, Swine, Swine Diseases (immunology), Swine Diseases (prevention & control), Swine Diseases (virology), Viral Vaccines (administration & dosage).
- MESH :
- chemical , administration & dosage : Viral Vaccines.
- chemical , blood : Antigens, CD79.
- immunology : Swine Diseases.
- prevention & control : Circoviridae Infections, Swine Diseases.
- veterinary : Circoviridae Infections.
- virology : Circoviridae Infections, Feces, Swine Diseases.
- Animals, Circovirus, Female, Immunity, Cellular, Real-Time Polymerase Chain Reaction, Swine.
Abstract
We investigated porcine circovirus type 2 (PCV2) virological profiles in herds affected (PCVAD-AH,
Url:
PubMed: 27247462
PubMed Central: 4866667
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PMC:4866667Le document en format XML
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vétérinaire)</term><term>Infections à Circoviridae (virologie)</term><term>Maladies des porcs ()</term><term>Maladies des porcs (immunologie)</term><term>Maladies des porcs (virologie)</term><term>Réaction de polymérisation en chaine en temps réel</term><term>Suidae</term><term>Vaccins antiviraux (administration et posologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Viral Vaccines</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Antigens, CD79</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Vaccins antiviraux</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Maladies des porcs</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Swine Diseases</term></keywords><keywords scheme="MESH" qualifier="médecine vétérinaire" xml:lang="fr"><term>Infections à Circoviridae</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Circoviridae Infections</term><term>Swine Diseases</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Antigènes CD79</term></keywords><keywords scheme="MESH" qualifier="veterinary" xml:lang="en"><term>Circoviridae Infections</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Fèces</term><term>Infections à Circoviridae</term><term>Maladies des porcs</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Circoviridae Infections</term><term>Feces</term><term>Swine Diseases</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Circovirus</term><term>Female</term><term>Immunity, Cellular</term><term>Real-Time Polymerase Chain Reaction</term><term>Swine</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Circovirus</term><term>Femelle</term><term>Immunité cellulaire</term><term>Infections à Circoviridae</term><term>Maladies des porcs</term><term>Réaction de polymérisation en chaine en temps réel</term><term>Suidae</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>We investigated porcine circovirus type 2 (PCV2) virological profiles in herds affected (PCVAD-AH, <italic>n</italic> = 5) or non-affected (PCVAD-NAH, <italic>n</italic> = 4) by PCV2-associated diseases (PCVAD), before and after 1 y of PCV2 gilt and sow vaccination. Fresh feces from the floor (5 pens/age/farm) and 5 blood samples (1/pen) were collected at 3, 9, 15, 21 wk. Individual feces and blood samples were collected from 5 gilts and 15 sows. Sampling was repeated 1 y after vaccination. Quantitative PCR on feces, PCV2 antibodies in blood serum and cell-mediated immunity were investigated. Before vaccination, pigs of PCVAD-AH had higher viral load in feces (9 and 15 wk), lower IgG and higher IgM (3 wk) and lower lymphocyte counts (9 and 15 wk) suggesting immunosuppression. Vaccination reduced viral load in growers, increased IgG (3 wk) suggesting improved maternal immunity, reduced IgM (3 wk), increased total antibody titers in sows and increased CD79a cells in the pigs.</p></div></front></TEI><double pmid="27247462"><pmc><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Effect of sow vaccination against porcine circovirus type 2 (PCV2) on virological profiles in herds with or without PCV2 systemic disease</title><author><name sortKey="Lopez Rodriguez, Alfonso" sort="Lopez Rodriguez, Alfonso" uniqKey="Lopez Rodriguez A" first="Alfonso" last="Lopez-Rodriguez">Alfonso Lopez-Rodriguez</name></author><author><name sortKey="Dewulf, Jeroen" sort="Dewulf, Jeroen" uniqKey="Dewulf J" first="Jeroen" last="Dewulf">Jeroen Dewulf</name></author><author><name sortKey="Meyns, Tom" sort="Meyns, Tom" uniqKey="Meyns T" first="Tom" last="Meyns">Tom Meyns</name></author><author><name sortKey="Del Pozo Sacristan, Ruben" sort="Del Pozo Sacristan, Ruben" uniqKey="Del Pozo Sacristan R" first="Rubén" last="Del-Pozo-Sacristán">Rubén Del-Pozo-Sacristán</name></author><author><name sortKey="Andreoni, Christine" sort="Andreoni, Christine" uniqKey="Andreoni C" first="Christine" last="Andreoni">Christine Andreoni</name></author><author><name sortKey="Goubier, Anne" sort="Goubier, Anne" uniqKey="Goubier A" first="Anne" last="Goubier">Anne Goubier</name></author><author><name sortKey="Chapat, Ludivine" sort="Chapat, Ludivine" uniqKey="Chapat L" first="Ludivine" last="Chapat">Ludivine Chapat</name></author><author><name sortKey="Charreyre, Catherine" sort="Charreyre, Catherine" uniqKey="Charreyre C" first="Catherine" last="Charreyre">Catherine Charreyre</name></author><author><name sortKey="Joisel, Francois" sort="Joisel, Francois" uniqKey="Joisel F" first="François" last="Joisel">François Joisel</name></author><author><name sortKey="Maes, Dominiek" sort="Maes, Dominiek" uniqKey="Maes D" first="Dominiek" last="Maes">Dominiek Maes</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27247462</idno><idno type="pmc">4866667</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866667</idno><idno type="RBID">PMC:4866667</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">000438</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000438</idno><idno type="wicri:Area/Pmc/Curation">000438</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000438</idno><idno type="wicri:Area/Pmc/Checkpoint">000988</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000988</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Effect of sow vaccination against porcine circovirus type 2 (PCV2) on virological profiles in herds with or without PCV2 systemic disease</title><author><name sortKey="Lopez Rodriguez, Alfonso" sort="Lopez Rodriguez, Alfonso" uniqKey="Lopez Rodriguez A" first="Alfonso" last="Lopez-Rodriguez">Alfonso Lopez-Rodriguez</name></author><author><name sortKey="Dewulf, Jeroen" sort="Dewulf, Jeroen" uniqKey="Dewulf J" first="Jeroen" last="Dewulf">Jeroen Dewulf</name></author><author><name sortKey="Meyns, Tom" sort="Meyns, Tom" uniqKey="Meyns T" first="Tom" last="Meyns">Tom Meyns</name></author><author><name sortKey="Del Pozo Sacristan, Ruben" sort="Del Pozo Sacristan, Ruben" uniqKey="Del Pozo Sacristan R" first="Rubén" last="Del-Pozo-Sacristán">Rubén Del-Pozo-Sacristán</name></author><author><name sortKey="Andreoni, Christine" sort="Andreoni, Christine" uniqKey="Andreoni C" first="Christine" last="Andreoni">Christine Andreoni</name></author><author><name sortKey="Goubier, Anne" sort="Goubier, Anne" uniqKey="Goubier A" first="Anne" last="Goubier">Anne Goubier</name></author><author><name sortKey="Chapat, Ludivine" sort="Chapat, Ludivine" uniqKey="Chapat L" first="Ludivine" last="Chapat">Ludivine Chapat</name></author><author><name sortKey="Charreyre, Catherine" sort="Charreyre, Catherine" uniqKey="Charreyre C" first="Catherine" last="Charreyre">Catherine Charreyre</name></author><author><name sortKey="Joisel, Francois" sort="Joisel, Francois" uniqKey="Joisel F" first="François" last="Joisel">François Joisel</name></author><author><name sortKey="Maes, Dominiek" sort="Maes, Dominiek" uniqKey="Maes D" first="Dominiek" last="Maes">Dominiek Maes</name></author></analytic><series><title level="j">The Canadian Veterinary Journal</title><idno type="ISSN">0008-5286</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>We investigated porcine circovirus type 2 (PCV2) virological profiles in herds affected (PCVAD-AH, <italic>n</italic> = 5) or non-affected (PCVAD-NAH, <italic>n</italic> = 4) by PCV2-associated diseases (PCVAD), before and after 1 y of PCV2 gilt and sow vaccination. Fresh feces from the floor (5 pens/age/farm) and 5 blood samples (1/pen) were collected at 3, 9, 15, 21 wk. Individual feces and blood samples were collected from 5 gilts and 15 sows. Sampling was repeated 1 y after vaccination. Quantitative PCR on feces, PCV2 antibodies in blood serum and cell-mediated immunity were investigated. Before vaccination, pigs of PCVAD-AH had higher viral load in feces (9 and 15 wk), lower IgG and higher IgM (3 wk) and lower lymphocyte counts (9 and 15 wk) suggesting immunosuppression. Vaccination reduced viral load in growers, increased IgG (3 wk) suggesting improved maternal immunity, reduced IgM (3 wk), increased total antibody titers in sows and increased CD79a cells in the pigs.</p></div></front></TEI></pmc><pubmed><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Effect of sow vaccination against porcine circovirus type 2 (PCV2) on virological profiles in herds with or without PCV2 systemic disease.</title><author><name sortKey="Lopez Rodriguez, Alfonso" sort="Lopez Rodriguez, Alfonso" uniqKey="Lopez Rodriguez A" first="Alfonso" last="Lopez-Rodriguez">Alfonso Lopez-Rodriguez</name><affiliation wicri:level="4"><nlm:affiliation>Faculty of Veterinary Medicine, Ghent University, Belgium (Lopez-Rodriguez, Dewulf, Del-Pozo-Sacristán, Maes); Merial SAS, Lyon, France (Meyns, Andreoni, Chapat, Charreyre, Joisel); PX Biosolutions, South Melbourne, Australia (Goubier).</nlm:affiliation><orgName type="university">Université de Gand</orgName><country>Belgique</country><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Dewulf, Jeroen" sort="Dewulf, Jeroen" uniqKey="Dewulf J" first="Jeroen" last="Dewulf">Jeroen Dewulf</name><affiliation wicri:level="4"><nlm:affiliation>Faculty of Veterinary Medicine, Ghent University, Belgium (Lopez-Rodriguez, Dewulf, Del-Pozo-Sacristán, Maes); Merial SAS, Lyon, France (Meyns, Andreoni, Chapat, Charreyre, Joisel); PX Biosolutions, South Melbourne, Australia (Goubier).</nlm:affiliation><orgName type="university">Université de Gand</orgName><country>Belgique</country><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Meyns, Tom" sort="Meyns, Tom" uniqKey="Meyns T" first="Tom" last="Meyns">Tom Meyns</name><affiliation wicri:level="4"><nlm:affiliation>Faculty of Veterinary Medicine, Ghent University, Belgium (Lopez-Rodriguez, Dewulf, Del-Pozo-Sacristán, Maes); Merial SAS, Lyon, France (Meyns, Andreoni, Chapat, Charreyre, Joisel); PX Biosolutions, South Melbourne, Australia (Goubier).</nlm:affiliation><orgName type="university">Université de Gand</orgName><country>Belgique</country><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Del Pozo Sacristan, Ruben" sort="Del Pozo Sacristan, Ruben" uniqKey="Del Pozo Sacristan R" first="Rubén" last="Del-Pozo-Sacristán">Rubén Del-Pozo-Sacristán</name><affiliation wicri:level="4"><nlm:affiliation>Faculty of Veterinary Medicine, Ghent University, Belgium (Lopez-Rodriguez, Dewulf, Del-Pozo-Sacristán, Maes); Merial SAS, Lyon, France (Meyns, Andreoni, Chapat, Charreyre, Joisel); PX Biosolutions, South Melbourne, Australia (Goubier).</nlm:affiliation><orgName type="university">Université de Gand</orgName><country>Belgique</country><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Andreoni, Christine" sort="Andreoni, Christine" uniqKey="Andreoni C" first="Christine" last="Andreoni">Christine Andreoni</name><affiliation wicri:level="4"><nlm:affiliation>Faculty of Veterinary Medicine, Ghent University, Belgium (Lopez-Rodriguez, Dewulf, Del-Pozo-Sacristán, Maes); Merial SAS, Lyon, France (Meyns, Andreoni, Chapat, Charreyre, Joisel); PX Biosolutions, South Melbourne, Australia (Goubier).</nlm:affiliation><orgName type="university">Université de Gand</orgName><country>Belgique</country><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Goubier, Anne" sort="Goubier, Anne" uniqKey="Goubier A" first="Anne" last="Goubier">Anne Goubier</name><affiliation wicri:level="4"><nlm:affiliation>Faculty of Veterinary Medicine, Ghent University, Belgium (Lopez-Rodriguez, Dewulf, Del-Pozo-Sacristán, Maes); Merial SAS, Lyon, France (Meyns, Andreoni, Chapat, Charreyre, Joisel); PX Biosolutions, South Melbourne, Australia (Goubier).</nlm:affiliation><orgName type="university">Université de Gand</orgName><country>Belgique</country><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Chapat, Ludivine" sort="Chapat, Ludivine" uniqKey="Chapat L" first="Ludivine" last="Chapat">Ludivine Chapat</name><affiliation wicri:level="4"><nlm:affiliation>Faculty of Veterinary Medicine, Ghent University, Belgium (Lopez-Rodriguez, Dewulf, Del-Pozo-Sacristán, Maes); Merial SAS, Lyon, France (Meyns, Andreoni, Chapat, Charreyre, Joisel); PX Biosolutions, South Melbourne, Australia (Goubier).</nlm:affiliation><orgName type="university">Université de Gand</orgName><country>Belgique</country><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Charreyre, Catherine" sort="Charreyre, Catherine" uniqKey="Charreyre C" first="Catherine" last="Charreyre">Catherine Charreyre</name><affiliation wicri:level="4"><nlm:affiliation>Faculty of Veterinary Medicine, Ghent University, Belgium (Lopez-Rodriguez, Dewulf, Del-Pozo-Sacristán, Maes); Merial SAS, Lyon, France (Meyns, Andreoni, Chapat, Charreyre, Joisel); PX Biosolutions, South Melbourne, Australia (Goubier).</nlm:affiliation><orgName type="university">Université de Gand</orgName><country>Belgique</country><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Joisel, Francois" sort="Joisel, Francois" uniqKey="Joisel F" first="François" last="Joisel">François Joisel</name><affiliation wicri:level="4"><nlm:affiliation>Faculty of Veterinary Medicine, Ghent University, Belgium (Lopez-Rodriguez, Dewulf, Del-Pozo-Sacristán, Maes); Merial SAS, Lyon, France (Meyns, Andreoni, Chapat, Charreyre, Joisel); PX Biosolutions, South Melbourne, Australia (Goubier).</nlm:affiliation><orgName type="university">Université de Gand</orgName><country>Belgique</country><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Maes, Dominiek" sort="Maes, Dominiek" uniqKey="Maes D" first="Dominiek" last="Maes">Dominiek Maes</name><affiliation wicri:level="4"><nlm:affiliation>Faculty of Veterinary Medicine, Ghent University, Belgium (Lopez-Rodriguez, Dewulf, Del-Pozo-Sacristán, Maes); Merial SAS, Lyon, France (Meyns, Andreoni, Chapat, Charreyre, Joisel); PX Biosolutions, South Melbourne, Australia (Goubier).</nlm:affiliation><orgName type="university">Université de Gand</orgName><country>Belgique</country><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2016">2016</date><idno type="RBID">pubmed:27247462</idno><idno type="pmid">27247462</idno><idno type="wicri:Area/PubMed/Corpus">001D11</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001D11</idno><idno type="wicri:Area/PubMed/Curation">001C87</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001C87</idno><idno type="wicri:Area/PubMed/Checkpoint">001C87</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001C87</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Effect of sow vaccination against porcine circovirus type 2 (PCV2) on virological profiles in herds with or without PCV2 systemic disease.</title><author><name sortKey="Lopez Rodriguez, Alfonso" sort="Lopez Rodriguez, Alfonso" uniqKey="Lopez Rodriguez A" first="Alfonso" last="Lopez-Rodriguez">Alfonso Lopez-Rodriguez</name><affiliation wicri:level="4"><nlm:affiliation>Faculty of Veterinary Medicine, Ghent University, Belgium (Lopez-Rodriguez, Dewulf, Del-Pozo-Sacristán, Maes); Merial SAS, Lyon, France (Meyns, Andreoni, Chapat, Charreyre, Joisel); PX Biosolutions, South Melbourne, Australia (Goubier).</nlm:affiliation><orgName type="university">Université de Gand</orgName><country>Belgique</country><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Dewulf, Jeroen" sort="Dewulf, Jeroen" uniqKey="Dewulf J" first="Jeroen" last="Dewulf">Jeroen Dewulf</name><affiliation wicri:level="4"><nlm:affiliation>Faculty of Veterinary Medicine, Ghent University, Belgium (Lopez-Rodriguez, Dewulf, Del-Pozo-Sacristán, Maes); Merial SAS, Lyon, France (Meyns, Andreoni, Chapat, Charreyre, Joisel); PX Biosolutions, South Melbourne, Australia (Goubier).</nlm:affiliation><orgName type="university">Université de Gand</orgName><country>Belgique</country><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Meyns, Tom" sort="Meyns, Tom" uniqKey="Meyns T" first="Tom" last="Meyns">Tom Meyns</name><affiliation wicri:level="4"><nlm:affiliation>Faculty of Veterinary Medicine, Ghent University, Belgium (Lopez-Rodriguez, Dewulf, Del-Pozo-Sacristán, Maes); Merial SAS, Lyon, France (Meyns, Andreoni, Chapat, Charreyre, Joisel); PX Biosolutions, South Melbourne, Australia (Goubier).</nlm:affiliation><orgName type="university">Université de Gand</orgName><country>Belgique</country><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Del Pozo Sacristan, Ruben" sort="Del Pozo Sacristan, Ruben" uniqKey="Del Pozo Sacristan R" first="Rubén" last="Del-Pozo-Sacristán">Rubén Del-Pozo-Sacristán</name><affiliation wicri:level="4"><nlm:affiliation>Faculty of Veterinary Medicine, Ghent University, Belgium (Lopez-Rodriguez, Dewulf, Del-Pozo-Sacristán, Maes); Merial SAS, Lyon, France (Meyns, Andreoni, Chapat, Charreyre, Joisel); PX Biosolutions, South Melbourne, Australia (Goubier).</nlm:affiliation><orgName type="university">Université de Gand</orgName><country>Belgique</country><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Andreoni, Christine" sort="Andreoni, Christine" uniqKey="Andreoni C" first="Christine" last="Andreoni">Christine Andreoni</name><affiliation wicri:level="4"><nlm:affiliation>Faculty of Veterinary Medicine, Ghent University, Belgium (Lopez-Rodriguez, Dewulf, Del-Pozo-Sacristán, Maes); Merial SAS, Lyon, France (Meyns, Andreoni, Chapat, Charreyre, Joisel); PX Biosolutions, South Melbourne, Australia (Goubier).</nlm:affiliation><orgName type="university">Université de Gand</orgName><country>Belgique</country><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Goubier, Anne" sort="Goubier, Anne" uniqKey="Goubier A" first="Anne" last="Goubier">Anne Goubier</name><affiliation wicri:level="4"><nlm:affiliation>Faculty of Veterinary Medicine, Ghent University, Belgium (Lopez-Rodriguez, Dewulf, Del-Pozo-Sacristán, Maes); Merial SAS, Lyon, France (Meyns, Andreoni, Chapat, Charreyre, Joisel); PX Biosolutions, South Melbourne, Australia (Goubier).</nlm:affiliation><orgName type="university">Université de Gand</orgName><country>Belgique</country><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Chapat, Ludivine" sort="Chapat, Ludivine" uniqKey="Chapat L" first="Ludivine" last="Chapat">Ludivine Chapat</name><affiliation wicri:level="4"><nlm:affiliation>Faculty of Veterinary Medicine, Ghent University, Belgium (Lopez-Rodriguez, Dewulf, Del-Pozo-Sacristán, Maes); Merial SAS, Lyon, France (Meyns, Andreoni, Chapat, Charreyre, Joisel); PX Biosolutions, South Melbourne, Australia (Goubier).</nlm:affiliation><orgName type="university">Université de Gand</orgName><country>Belgique</country><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Charreyre, Catherine" sort="Charreyre, Catherine" uniqKey="Charreyre C" first="Catherine" last="Charreyre">Catherine Charreyre</name><affiliation wicri:level="4"><nlm:affiliation>Faculty of Veterinary Medicine, Ghent University, Belgium (Lopez-Rodriguez, Dewulf, Del-Pozo-Sacristán, Maes); Merial SAS, Lyon, France (Meyns, Andreoni, Chapat, Charreyre, Joisel); PX Biosolutions, South Melbourne, Australia (Goubier).</nlm:affiliation><orgName type="university">Université de Gand</orgName><country>Belgique</country><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Joisel, Francois" sort="Joisel, Francois" uniqKey="Joisel F" first="François" last="Joisel">François Joisel</name><affiliation wicri:level="4"><nlm:affiliation>Faculty of Veterinary Medicine, Ghent University, Belgium (Lopez-Rodriguez, Dewulf, Del-Pozo-Sacristán, Maes); Merial SAS, Lyon, France (Meyns, Andreoni, Chapat, Charreyre, Joisel); PX Biosolutions, South Melbourne, Australia (Goubier).</nlm:affiliation><orgName type="university">Université de Gand</orgName><country>Belgique</country><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Maes, Dominiek" sort="Maes, Dominiek" uniqKey="Maes D" first="Dominiek" last="Maes">Dominiek Maes</name><affiliation wicri:level="4"><nlm:affiliation>Faculty of Veterinary Medicine, Ghent University, Belgium (Lopez-Rodriguez, Dewulf, Del-Pozo-Sacristán, Maes); Merial SAS, Lyon, France (Meyns, Andreoni, Chapat, Charreyre, Joisel); PX Biosolutions, South Melbourne, Australia (Goubier).</nlm:affiliation><orgName type="university">Université de Gand</orgName><country>Belgique</country><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author></analytic><series><title level="j">The Canadian veterinary journal = La revue veterinaire canadienne</title><idno type="ISSN">0008-5286</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Antigens, CD79 (blood)</term><term>Circoviridae Infections (prevention & control)</term><term>Circoviridae Infections (veterinary)</term><term>Circoviridae Infections (virology)</term><term>Circovirus</term><term>Feces (virology)</term><term>Female</term><term>Immunity, Cellular</term><term>Real-Time Polymerase Chain Reaction</term><term>Swine</term><term>Swine Diseases (immunology)</term><term>Swine Diseases (prevention & control)</term><term>Swine Diseases (virology)</term><term>Viral Vaccines (administration & dosage)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Antigènes CD79 (sang)</term><term>Circovirus</term><term>Femelle</term><term>Fèces (virologie)</term><term>Immunité cellulaire</term><term>Infections à Circoviridae ()</term><term>Infections à Circoviridae (médecine vétérinaire)</term><term>Infections à Circoviridae (virologie)</term><term>Maladies des porcs ()</term><term>Maladies des porcs (immunologie)</term><term>Maladies des porcs (virologie)</term><term>Réaction de polymérisation en chaine en temps réel</term><term>Suidae</term><term>Vaccins antiviraux (administration et posologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Viral Vaccines</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Antigens, CD79</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Vaccins antiviraux</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Maladies des porcs</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Swine Diseases</term></keywords><keywords scheme="MESH" qualifier="médecine vétérinaire" xml:lang="fr"><term>Infections à Circoviridae</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Circoviridae Infections</term><term>Swine Diseases</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Antigènes CD79</term></keywords><keywords scheme="MESH" qualifier="veterinary" xml:lang="en"><term>Circoviridae Infections</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Fèces</term><term>Infections à Circoviridae</term><term>Maladies des porcs</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Circoviridae Infections</term><term>Feces</term><term>Swine Diseases</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Circovirus</term><term>Female</term><term>Immunity, Cellular</term><term>Real-Time Polymerase Chain Reaction</term><term>Swine</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Circovirus</term><term>Femelle</term><term>Immunité cellulaire</term><term>Infections à Circoviridae</term><term>Maladies des porcs</term><term>Réaction de polymérisation en chaine en temps réel</term><term>Suidae</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We investigated porcine circovirus type 2 (PCV2) virological profiles in herds affected (PCVAD-AH, n = 5) or non-affected (PCVAD-NAH, n = 4) by PCV2-associated diseases (PCVAD), before and after 1 y of PCV2 gilt and sow vaccination. Fresh feces from the floor (5 pens/age/farm) and 5 blood samples (1/pen) were collected at 3, 9, 15, 21 wk. Individual feces and blood samples were collected from 5 gilts and 15 sows. Sampling was repeated 1 y after vaccination. Quantitative PCR on feces, PCV2 antibodies in blood serum and cell-mediated immunity were investigated. Before vaccination, pigs of PCVAD-AH had higher viral load in feces (9 and 15 wk), lower IgG and higher IgM (3 wk) and lower lymphocyte counts (9 and 15 wk) suggesting immunosuppression. Vaccination reduced viral load in growers, increased IgG (3 wk) suggesting improved maternal immunity, reduced IgM (3 wk), increased total antibody titers in sows and increased CD79a cells in the pigs.</div></front></TEI></pubmed></double></record>Pour manipuler ce document sous Unix (Dilib)
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