AustralieFrV1, Ncbi, Merge, bibRecord, 002F75

Anthropometric Factors and Thyroid Cancer Risk by Histological Subtype: Pooled Analysis of 22 Prospective Studies

Identifieur interne : 002F75 ( Ncbi/Merge ); précédent : 002F74; suivant : 002F76

Anthropometric Factors and Thyroid Cancer Risk by Histological Subtype: Pooled Analysis of 22 Prospective Studies

Auteurs : Cari M. Kitahara ; Marjorie L. Mccullough ; Silvia Franceschi ; Sabina Rinaldi ; Alicja Wolk ; Gila Neta ; Hans Olov Adami ; Kristin Anderson ; Gabriella Andreotti ; Laura E. Beane Freeman ; Leslie Bernstein ; Julie E. Buring ; Francoise Clavel-Chapelon ; Lisa A. De Roo ; Yu-Tang Gao ; J. Michael Gaziano ; Graham G. Giles ; Niclas H Kansson ; Pamela L. Horn-Ross ; Vicki A. Kirsh ; Martha S. Linet ; Robert J. Macinnis ; Nicola Orsini ; Yikyung Park ; Alpa V. Patel ; Mark P. Purdue ; Elio Riboli ; Kimberly Robien ; Thomas Rohan ; Dale P. Sandler ; Catherine Schairer ; Arthur B. Schneider ; Howard D. Sesso ; Xiao-Ou Shu ; Pramil N. Singh ; Piet A. Van Den Brandt ; Elizabeth Ward ; Elisabete Weiderpass ; Emily White ; Yong-Bing Xiang ; Anne Zeleniuch-Jacquotte ; Wei Zheng ; Patricia Hartge ; Amy Berrington De González

Source :

Thyroid [ 1050-7256 ] ; 2016.

RBID : PMC:4754509

Descripteurs français

KwdFr :
- Adulte, Adulte d'âge moyen, Anthropométrie, Carcinomes (diagnostic), Carcinomes (mortalité), Carcinomes (physiopathologie), Facteurs de risque, Femelle, Humains, Indice de masse corporelle, Modèles de hasards proportionnels, Mâle, Sujet âgé, Sujet âgé de 80 ans ou plus, Tabagisme, Tour de taille, Tumeurs de la thyroïde (diagnostic), Tumeurs de la thyroïde (mortalité), Tumeurs de la thyroïde (physiopathologie), Études prospectives.
MESH :
- diagnostic : Carcinomes, Tumeurs de la thyroïde.
- mortalité : Carcinomes, Tumeurs de la thyroïde.
- physiopathologie : Carcinomes, Tumeurs de la thyroïde.
- Adulte, Adulte d'âge moyen, Anthropométrie, Facteurs de risque, Femelle, Humains, Indice de masse corporelle, Modèles de hasards proportionnels, Mâle, Sujet âgé, Sujet âgé de 80 ans ou plus, Tabagisme, Tour de taille, Études prospectives.

English descriptors

KwdEn :
- Adult, Aged, Aged, 80 and over, Anthropometry, Body Mass Index, Carcinoma (diagnosis), Carcinoma (mortality), Carcinoma (physiopathology), Female, Humans, Male, Middle Aged, Proportional Hazards Models, Prospective Studies, Risk Factors, Smoking, Thyroid Neoplasms (diagnosis), Thyroid Neoplasms (mortality), Thyroid Neoplasms (physiopathology), Waist Circumference.
MESH :
- diagnosis : Carcinoma, Thyroid Neoplasms.
- mortality : Carcinoma, Thyroid Neoplasms.
- physiopathology : Carcinoma, Thyroid Neoplasms.
- Adult, Aged, Aged, 80 and over, Anthropometry, Body Mass Index, Female, Humans, Male, Middle Aged, Proportional Hazards Models, Prospective Studies, Risk Factors, Smoking, Waist Circumference.

Abstract

Background: Greater height and body mass index (BMI) have been associated with an increased risk of thyroid cancer, particularly papillary carcinoma, the most common and least aggressive subtype. Few studies have evaluated these associations in relation to other, more aggressive histologic types or thyroid cancer-specific mortality.

Methods: This large pooled analysis of 22 prospective studies (833,176 men and 1,260,871 women) investigated thyroid cancer incidence associated with greater height, BMI at baseline and young adulthood, and adulthood BMI gain (difference between young-adult and baseline BMI), overall and separately by sex and histological subtype using multivariable Cox proportional hazards regression models. Associations with thyroid cancer mortality were investigated in a subset of cohorts (578,922 men and 774,373 women) that contributed cause of death information.

Results: During follow-up, 2996 incident thyroid cancers and 104 thyroid cancer deaths were identified. All anthropometric factors were positively associated with thyroid cancer incidence: hazard ratios (HR) [confidence intervals (CIs)] for height (per 5 cm) = 1.07 [1.04–1.10], BMI (per 5 kg/m²) = 1.06 [1.02–1.10], waist circumference (per 5 cm) = 1.03 [1.01–1.05], young-adult BMI (per 5 kg/m²) = 1.13 [1.02–1.25], and adulthood BMI gain (per 5 kg/m²) = 1.07 [1.00–1.15]. Associations for baseline BMI and waist circumference were attenuated after mutual adjustment. Baseline BMI was more strongly associated with risk in men compared with women (p = 0.04). Positive associations were observed for papillary, follicular, and anaplastic, but not medullary, thyroid carcinomas. Similar, but stronger, associations were observed for thyroid cancer mortality.

Conclusion: The results suggest that greater height and excess adiposity throughout adulthood are associated with higher incidence of most major types of thyroid cancer, including the least common but most aggressive form, anaplastic carcinoma, and higher thyroid cancer mortality. Potential underlying biological mechanisms should be explored in future studies.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754509

DOI: 10.1089/thy.2015.0319
PubMed: 26756356
PubMed Central: 4754509

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PMC:4754509

Le document en format XML

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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Anthropometric Factors and Thyroid Cancer Risk by Histological Subtype: Pooled Analysis of 22 Prospective Studies</title>
<author><name sortKey="Kitahara, Cari M" sort="Kitahara, Cari M" uniqKey="Kitahara C" first="Cari M." last="Kitahara">Cari M. Kitahara</name>
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<author><name sortKey="Mccullough, Marjorie L" sort="Mccullough, Marjorie L" uniqKey="Mccullough M" first="Marjorie L." last="Mccullough">Marjorie L. Mccullough</name>
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<author><name sortKey="Franceschi, Silvia" sort="Franceschi, Silvia" uniqKey="Franceschi S" first="Silvia" last="Franceschi">Silvia Franceschi</name>
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<author><name sortKey="Rinaldi, Sabina" sort="Rinaldi, Sabina" uniqKey="Rinaldi S" first="Sabina" last="Rinaldi">Sabina Rinaldi</name>
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</affiliation>
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<author><name sortKey="Bernstein, Leslie" sort="Bernstein, Leslie" uniqKey="Bernstein L" first="Leslie" last="Bernstein">Leslie Bernstein</name>
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<author><name sortKey="Buring, Julie E" sort="Buring, Julie E" uniqKey="Buring J" first="Julie E." last="Buring">Julie E. Buring</name>
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</affiliation>
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<author><name sortKey="Gaziano, J Michael" sort="Gaziano, J Michael" uniqKey="Gaziano J" first="J. Michael" last="Gaziano">J. Michael Gaziano</name>
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</affiliation>
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</affiliation>
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<author><name sortKey="Kirsh, Vicki A" sort="Kirsh, Vicki A" uniqKey="Kirsh V" first="Vicki A." last="Kirsh">Vicki A. Kirsh</name>
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<affiliation><nlm:aff id="aff22"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Linet, Martha S" sort="Linet, Martha S" uniqKey="Linet M" first="Martha S." last="Linet">Martha S. Linet</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Macinnis, Robert J" sort="Macinnis, Robert J" uniqKey="Macinnis R" first="Robert J." last="Macinnis">Robert J. Macinnis</name>
<affiliation><nlm:aff id="aff18"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff19"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Orsini, Nicola" sort="Orsini, Nicola" uniqKey="Orsini N" first="Nicola" last="Orsini">Nicola Orsini</name>
<affiliation><nlm:aff id="aff4"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Park, Yikyung" sort="Park, Yikyung" uniqKey="Park Y" first="Yikyung" last="Park">Yikyung Park</name>
<affiliation><nlm:aff id="aff23"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Patel, Alpa V" sort="Patel, Alpa V" uniqKey="Patel A" first="Alpa V." last="Patel">Alpa V. Patel</name>
<affiliation><nlm:aff id="aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Purdue, Mark P" sort="Purdue, Mark P" uniqKey="Purdue M" first="Mark P." last="Purdue">Mark P. Purdue</name>
<affiliation><nlm:aff id="aff24"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Riboli, Elio" sort="Riboli, Elio" uniqKey="Riboli E" first="Elio" last="Riboli">Elio Riboli</name>
<affiliation><nlm:aff id="aff25"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Robien, Kimberly" sort="Robien, Kimberly" uniqKey="Robien K" first="Kimberly" last="Robien">Kimberly Robien</name>
<affiliation><nlm:aff id="aff26"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rohan, Thomas" sort="Rohan, Thomas" uniqKey="Rohan T" first="Thomas" last="Rohan">Thomas Rohan</name>
<affiliation><nlm:aff id="aff27"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Sandler, Dale P" sort="Sandler, Dale P" uniqKey="Sandler D" first="Dale P." last="Sandler">Dale P. Sandler</name>
<affiliation><nlm:aff id="aff14"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Schairer, Catherine" sort="Schairer, Catherine" uniqKey="Schairer C" first="Catherine" last="Schairer">Catherine Schairer</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Schneider, Arthur B" sort="Schneider, Arthur B" uniqKey="Schneider A" first="Arthur B." last="Schneider">Arthur B. Schneider</name>
<affiliation><nlm:aff id="aff28"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Sesso, Howard D" sort="Sesso, Howard D" uniqKey="Sesso H" first="Howard D." last="Sesso">Howard D. Sesso</name>
<affiliation><nlm:aff id="aff7"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff11"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff16"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Shu, Xiao Ou" sort="Shu, Xiao Ou" uniqKey="Shu X" first="Xiao-Ou" last="Shu">Xiao-Ou Shu</name>
<affiliation><nlm:aff id="aff29"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Singh, Pramil N" sort="Singh, Pramil N" uniqKey="Singh P" first="Pramil N." last="Singh">Pramil N. Singh</name>
<affiliation><nlm:aff id="aff30"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Van Den Brandt, Piet A" sort="Van Den Brandt, Piet A" uniqKey="Van Den Brandt P" first="Piet A." last="Van Den Brandt">Piet A. Van Den Brandt</name>
<affiliation><nlm:aff id="aff31"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ward, Elizabeth" sort="Ward, Elizabeth" uniqKey="Ward E" first="Elizabeth" last="Ward">Elizabeth Ward</name>
<affiliation><nlm:aff id="aff32"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name>
<affiliation><nlm:aff id="aff6"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff33"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff34"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff35"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="White, Emily" sort="White, Emily" uniqKey="White E" first="Emily" last="White">Emily White</name>
<affiliation><nlm:aff id="aff36"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff37"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Xiang, Yong Bing" sort="Xiang, Yong Bing" uniqKey="Xiang Y" first="Yong-Bing" last="Xiang">Yong-Bing Xiang</name>
<affiliation><nlm:aff id="aff15"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Zeleniuch Jacquotte, Anne" sort="Zeleniuch Jacquotte, Anne" uniqKey="Zeleniuch Jacquotte A" first="Anne" last="Zeleniuch-Jacquotte">Anne Zeleniuch-Jacquotte</name>
<affiliation><nlm:aff id="aff38"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Zheng, Wei" sort="Zheng, Wei" uniqKey="Zheng W" first="Wei" last="Zheng">Wei Zheng</name>
<affiliation><nlm:aff id="aff29"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hartge, Patricia" sort="Hartge, Patricia" uniqKey="Hartge P" first="Patricia" last="Hartge">Patricia Hartge</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Berrington De Gonzalez, Amy" sort="Berrington De Gonzalez, Amy" uniqKey="Berrington De Gonzalez A" first="Amy" last="Berrington De González">Amy Berrington De González</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Thyroid</title>
<idno type="ISSN">1050-7256</idno>
<idno type="eISSN">1557-9077</idno>
<imprint><date when="2016">2016</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Anthropometry</term>
<term>Body Mass Index</term>
<term>Carcinoma (diagnosis)</term>
<term>Carcinoma (mortality)</term>
<term>Carcinoma (physiopathology)</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Proportional Hazards Models</term>
<term>Prospective Studies</term>
<term>Risk Factors</term>
<term>Smoking</term>
<term>Thyroid Neoplasms (diagnosis)</term>
<term>Thyroid Neoplasms (mortality)</term>
<term>Thyroid Neoplasms (physiopathology)</term>
<term>Waist Circumference</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Anthropométrie</term>
<term>Carcinomes (diagnostic)</term>
<term>Carcinomes (mortalité)</term>
<term>Carcinomes (physiopathologie)</term>
<term>Facteurs de risque</term>
<term>Femelle</term>
<term>Humains</term>
<term>Indice de masse corporelle</term>
<term>Modèles de hasards proportionnels</term>
<term>Mâle</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Tabagisme</term>
<term>Tour de taille</term>
<term>Tumeurs de la thyroïde (diagnostic)</term>
<term>Tumeurs de la thyroïde (mortalité)</term>
<term>Tumeurs de la thyroïde (physiopathologie)</term>
<term>Études prospectives</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Carcinoma</term>
<term>Thyroid Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Carcinomes</term>
<term>Tumeurs de la thyroïde</term>
</keywords>
<keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Carcinoma</term>
<term>Thyroid Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Carcinomes</term>
<term>Tumeurs de la thyroïde</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Carcinomes</term>
<term>Tumeurs de la thyroïde</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Carcinoma</term>
<term>Thyroid Neoplasms</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Anthropometry</term>
<term>Body Mass Index</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Proportional Hazards Models</term>
<term>Prospective Studies</term>
<term>Risk Factors</term>
<term>Smoking</term>
<term>Waist Circumference</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Anthropométrie</term>
<term>Facteurs de risque</term>
<term>Femelle</term>
<term>Humains</term>
<term>Indice de masse corporelle</term>
<term>Modèles de hasards proportionnels</term>
<term>Mâle</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Tabagisme</term>
<term>Tour de taille</term>
<term>Études prospectives</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p><bold><italic>Background:</italic>
</bold>
 Greater height and body mass index (BMI) have been associated with an increased risk of thyroid cancer, particularly papillary carcinoma, the most common and least aggressive subtype. Few studies have evaluated these associations in relation to other, more aggressive histologic types or thyroid cancer-specific mortality.</p>
<p><bold><italic>Methods:</italic>
</bold>
 This large pooled analysis of 22 prospective studies (833,176 men and 1,260,871 women) investigated thyroid cancer incidence associated with greater height, BMI at baseline and young adulthood, and adulthood BMI gain (difference between young-adult and baseline BMI), overall and separately by sex and histological subtype using multivariable Cox proportional hazards regression models. Associations with thyroid cancer mortality were investigated in a subset of cohorts (578,922 men and 774,373 women) that contributed cause of death information.</p>
<p><bold><italic>Results:</italic>
</bold>
 During follow-up, 2996 incident thyroid cancers and 104 thyroid cancer deaths were identified. All anthropometric factors were positively associated with thyroid cancer incidence: hazard ratios (HR) [confidence intervals (CIs)] for height (per 5 cm) = 1.07 [1.04–1.10], BMI (per 5 kg/m<sup>2</sup>
) = 1.06 [1.02–1.10], waist circumference (per 5 cm) = 1.03 [1.01–1.05], young-adult BMI (per 5 kg/m<sup>2</sup>
) = 1.13 [1.02–1.25], and adulthood BMI gain (per 5 kg/m<sup>2</sup>
) = 1.07 [1.00–1.15]. Associations for baseline BMI and waist circumference were attenuated after mutual adjustment. Baseline BMI was more strongly associated with risk in men compared with women (<italic>p</italic>
 = 0.04). Positive associations were observed for papillary, follicular, and anaplastic, but not medullary, thyroid carcinomas. Similar, but stronger, associations were observed for thyroid cancer mortality.</p>
<p><bold><italic>Conclusion:</italic>
</bold>
 The results suggest that greater height and excess adiposity throughout adulthood are associated with higher incidence of most major types of thyroid cancer, including the least common but most aggressive form, anaplastic carcinoma, and higher thyroid cancer mortality. Potential underlying biological mechanisms should be explored in future studies.</p>
</div>
</front>
</TEI>
<double pmid="26756356"><pmc><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Anthropometric Factors and Thyroid Cancer Risk by Histological Subtype: Pooled Analysis of 22 Prospective Studies</title>
<author><name sortKey="Kitahara, Cari M" sort="Kitahara, Cari M" uniqKey="Kitahara C" first="Cari M." last="Kitahara">Cari M. Kitahara</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Mccullough, Marjorie L" sort="Mccullough, Marjorie L" uniqKey="Mccullough M" first="Marjorie L." last="Mccullough">Marjorie L. Mccullough</name>
<affiliation><nlm:aff id="aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Franceschi, Silvia" sort="Franceschi, Silvia" uniqKey="Franceschi S" first="Silvia" last="Franceschi">Silvia Franceschi</name>
<affiliation><nlm:aff id="aff3"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rinaldi, Sabina" sort="Rinaldi, Sabina" uniqKey="Rinaldi S" first="Sabina" last="Rinaldi">Sabina Rinaldi</name>
<affiliation><nlm:aff id="aff3"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Wolk, Alicja" sort="Wolk, Alicja" uniqKey="Wolk A" first="Alicja" last="Wolk">Alicja Wolk</name>
<affiliation><nlm:aff id="aff4"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Neta, Gila" sort="Neta, Gila" uniqKey="Neta G" first="Gila" last="Neta">Gila Neta</name>
<affiliation><nlm:aff id="aff5"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Olov Adami, Hans" sort="Olov Adami, Hans" uniqKey="Olov Adami H" first="Hans" last="Olov Adami">Hans Olov Adami</name>
<affiliation><nlm:aff id="aff6"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff7"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Anderson, Kristin" sort="Anderson, Kristin" uniqKey="Anderson K" first="Kristin" last="Anderson">Kristin Anderson</name>
<affiliation><nlm:aff id="aff8"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff9"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Andreotti, Gabriella" sort="Andreotti, Gabriella" uniqKey="Andreotti G" first="Gabriella" last="Andreotti">Gabriella Andreotti</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Beane Freeman, Laura E" sort="Beane Freeman, Laura E" uniqKey="Beane Freeman L" first="Laura E." last="Beane Freeman">Laura E. Beane Freeman</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Bernstein, Leslie" sort="Bernstein, Leslie" uniqKey="Bernstein L" first="Leslie" last="Bernstein">Leslie Bernstein</name>
<affiliation><nlm:aff id="aff10"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Buring, Julie E" sort="Buring, Julie E" uniqKey="Buring J" first="Julie E." last="Buring">Julie E. Buring</name>
<affiliation><nlm:aff id="aff7"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff11"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Clavel Chapelon, Francoise" sort="Clavel Chapelon, Francoise" uniqKey="Clavel Chapelon F" first="Francoise" last="Clavel-Chapelon">Francoise Clavel-Chapelon</name>
<affiliation><nlm:aff id="aff12"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="De Roo, Lisa A" sort="De Roo, Lisa A" uniqKey="De Roo L" first="Lisa A." last="De Roo">Lisa A. De Roo</name>
<affiliation><nlm:aff id="aff13"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff14"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Gao, Yu Tang" sort="Gao, Yu Tang" uniqKey="Gao Y" first="Yu-Tang" last="Gao">Yu-Tang Gao</name>
<affiliation><nlm:aff id="aff15"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Gaziano, J Michael" sort="Gaziano, J Michael" uniqKey="Gaziano J" first="J. Michael" last="Gaziano">J. Michael Gaziano</name>
<affiliation><nlm:aff id="aff11"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff16"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff17"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Giles, Graham G" sort="Giles, Graham G" uniqKey="Giles G" first="Graham G." last="Giles">Graham G. Giles</name>
<affiliation><nlm:aff id="aff18"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff19"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="H Kansson, Niclas" sort="H Kansson, Niclas" uniqKey="H Kansson N" first="Niclas" last="H Kansson">Niclas H Kansson</name>
<affiliation><nlm:aff id="aff4"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Horn Ross, Pamela L" sort="Horn Ross, Pamela L" uniqKey="Horn Ross P" first="Pamela L." last="Horn-Ross">Pamela L. Horn-Ross</name>
<affiliation><nlm:aff id="aff20"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kirsh, Vicki A" sort="Kirsh, Vicki A" uniqKey="Kirsh V" first="Vicki A." last="Kirsh">Vicki A. Kirsh</name>
<affiliation><nlm:aff id="aff21"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff22"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Linet, Martha S" sort="Linet, Martha S" uniqKey="Linet M" first="Martha S." last="Linet">Martha S. Linet</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Macinnis, Robert J" sort="Macinnis, Robert J" uniqKey="Macinnis R" first="Robert J." last="Macinnis">Robert J. Macinnis</name>
<affiliation><nlm:aff id="aff18"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff19"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Orsini, Nicola" sort="Orsini, Nicola" uniqKey="Orsini N" first="Nicola" last="Orsini">Nicola Orsini</name>
<affiliation><nlm:aff id="aff4"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Park, Yikyung" sort="Park, Yikyung" uniqKey="Park Y" first="Yikyung" last="Park">Yikyung Park</name>
<affiliation><nlm:aff id="aff23"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Patel, Alpa V" sort="Patel, Alpa V" uniqKey="Patel A" first="Alpa V." last="Patel">Alpa V. Patel</name>
<affiliation><nlm:aff id="aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Purdue, Mark P" sort="Purdue, Mark P" uniqKey="Purdue M" first="Mark P." last="Purdue">Mark P. Purdue</name>
<affiliation><nlm:aff id="aff24"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Riboli, Elio" sort="Riboli, Elio" uniqKey="Riboli E" first="Elio" last="Riboli">Elio Riboli</name>
<affiliation><nlm:aff id="aff25"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Robien, Kimberly" sort="Robien, Kimberly" uniqKey="Robien K" first="Kimberly" last="Robien">Kimberly Robien</name>
<affiliation><nlm:aff id="aff26"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rohan, Thomas" sort="Rohan, Thomas" uniqKey="Rohan T" first="Thomas" last="Rohan">Thomas Rohan</name>
<affiliation><nlm:aff id="aff27"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Sandler, Dale P" sort="Sandler, Dale P" uniqKey="Sandler D" first="Dale P." last="Sandler">Dale P. Sandler</name>
<affiliation><nlm:aff id="aff14"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Schairer, Catherine" sort="Schairer, Catherine" uniqKey="Schairer C" first="Catherine" last="Schairer">Catherine Schairer</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Schneider, Arthur B" sort="Schneider, Arthur B" uniqKey="Schneider A" first="Arthur B." last="Schneider">Arthur B. Schneider</name>
<affiliation><nlm:aff id="aff28"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Sesso, Howard D" sort="Sesso, Howard D" uniqKey="Sesso H" first="Howard D." last="Sesso">Howard D. Sesso</name>
<affiliation><nlm:aff id="aff7"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff11"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff16"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Shu, Xiao Ou" sort="Shu, Xiao Ou" uniqKey="Shu X" first="Xiao-Ou" last="Shu">Xiao-Ou Shu</name>
<affiliation><nlm:aff id="aff29"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Singh, Pramil N" sort="Singh, Pramil N" uniqKey="Singh P" first="Pramil N." last="Singh">Pramil N. Singh</name>
<affiliation><nlm:aff id="aff30"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Van Den Brandt, Piet A" sort="Van Den Brandt, Piet A" uniqKey="Van Den Brandt P" first="Piet A." last="Van Den Brandt">Piet A. Van Den Brandt</name>
<affiliation><nlm:aff id="aff31"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ward, Elizabeth" sort="Ward, Elizabeth" uniqKey="Ward E" first="Elizabeth" last="Ward">Elizabeth Ward</name>
<affiliation><nlm:aff id="aff32"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name>
<affiliation><nlm:aff id="aff6"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff33"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff34"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff35"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="White, Emily" sort="White, Emily" uniqKey="White E" first="Emily" last="White">Emily White</name>
<affiliation><nlm:aff id="aff36"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff37"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Xiang, Yong Bing" sort="Xiang, Yong Bing" uniqKey="Xiang Y" first="Yong-Bing" last="Xiang">Yong-Bing Xiang</name>
<affiliation><nlm:aff id="aff15"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Zeleniuch Jacquotte, Anne" sort="Zeleniuch Jacquotte, Anne" uniqKey="Zeleniuch Jacquotte A" first="Anne" last="Zeleniuch-Jacquotte">Anne Zeleniuch-Jacquotte</name>
<affiliation><nlm:aff id="aff38"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Zheng, Wei" sort="Zheng, Wei" uniqKey="Zheng W" first="Wei" last="Zheng">Wei Zheng</name>
<affiliation><nlm:aff id="aff29"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hartge, Patricia" sort="Hartge, Patricia" uniqKey="Hartge P" first="Patricia" last="Hartge">Patricia Hartge</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Berrington De Gonzalez, Amy" sort="Berrington De Gonzalez, Amy" uniqKey="Berrington De Gonzalez A" first="Amy" last="Berrington De González">Amy Berrington De González</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">26756356</idno>
<idno type="pmc">4754509</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754509</idno>
<idno type="RBID">PMC:4754509</idno>
<idno type="doi">10.1089/thy.2015.0319</idno>
<date when="2016">2016</date>
<idno type="wicri:Area/Pmc/Corpus">000501</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000501</idno>
<idno type="wicri:Area/Pmc/Curation">000501</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000501</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000B29</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000B29</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Anthropometric Factors and Thyroid Cancer Risk by Histological Subtype: Pooled Analysis of 22 Prospective Studies</title>
<author><name sortKey="Kitahara, Cari M" sort="Kitahara, Cari M" uniqKey="Kitahara C" first="Cari M." last="Kitahara">Cari M. Kitahara</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Mccullough, Marjorie L" sort="Mccullough, Marjorie L" uniqKey="Mccullough M" first="Marjorie L." last="Mccullough">Marjorie L. Mccullough</name>
<affiliation><nlm:aff id="aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Franceschi, Silvia" sort="Franceschi, Silvia" uniqKey="Franceschi S" first="Silvia" last="Franceschi">Silvia Franceschi</name>
<affiliation><nlm:aff id="aff3"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rinaldi, Sabina" sort="Rinaldi, Sabina" uniqKey="Rinaldi S" first="Sabina" last="Rinaldi">Sabina Rinaldi</name>
<affiliation><nlm:aff id="aff3"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Wolk, Alicja" sort="Wolk, Alicja" uniqKey="Wolk A" first="Alicja" last="Wolk">Alicja Wolk</name>
<affiliation><nlm:aff id="aff4"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Neta, Gila" sort="Neta, Gila" uniqKey="Neta G" first="Gila" last="Neta">Gila Neta</name>
<affiliation><nlm:aff id="aff5"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Olov Adami, Hans" sort="Olov Adami, Hans" uniqKey="Olov Adami H" first="Hans" last="Olov Adami">Hans Olov Adami</name>
<affiliation><nlm:aff id="aff6"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff7"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Anderson, Kristin" sort="Anderson, Kristin" uniqKey="Anderson K" first="Kristin" last="Anderson">Kristin Anderson</name>
<affiliation><nlm:aff id="aff8"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff9"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Andreotti, Gabriella" sort="Andreotti, Gabriella" uniqKey="Andreotti G" first="Gabriella" last="Andreotti">Gabriella Andreotti</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Beane Freeman, Laura E" sort="Beane Freeman, Laura E" uniqKey="Beane Freeman L" first="Laura E." last="Beane Freeman">Laura E. Beane Freeman</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Bernstein, Leslie" sort="Bernstein, Leslie" uniqKey="Bernstein L" first="Leslie" last="Bernstein">Leslie Bernstein</name>
<affiliation><nlm:aff id="aff10"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Buring, Julie E" sort="Buring, Julie E" uniqKey="Buring J" first="Julie E." last="Buring">Julie E. Buring</name>
<affiliation><nlm:aff id="aff7"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff11"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Clavel Chapelon, Francoise" sort="Clavel Chapelon, Francoise" uniqKey="Clavel Chapelon F" first="Francoise" last="Clavel-Chapelon">Francoise Clavel-Chapelon</name>
<affiliation><nlm:aff id="aff12"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="De Roo, Lisa A" sort="De Roo, Lisa A" uniqKey="De Roo L" first="Lisa A." last="De Roo">Lisa A. De Roo</name>
<affiliation><nlm:aff id="aff13"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff14"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Gao, Yu Tang" sort="Gao, Yu Tang" uniqKey="Gao Y" first="Yu-Tang" last="Gao">Yu-Tang Gao</name>
<affiliation><nlm:aff id="aff15"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Gaziano, J Michael" sort="Gaziano, J Michael" uniqKey="Gaziano J" first="J. Michael" last="Gaziano">J. Michael Gaziano</name>
<affiliation><nlm:aff id="aff11"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff16"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff17"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Giles, Graham G" sort="Giles, Graham G" uniqKey="Giles G" first="Graham G." last="Giles">Graham G. Giles</name>
<affiliation><nlm:aff id="aff18"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff19"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="H Kansson, Niclas" sort="H Kansson, Niclas" uniqKey="H Kansson N" first="Niclas" last="H Kansson">Niclas H Kansson</name>
<affiliation><nlm:aff id="aff4"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Horn Ross, Pamela L" sort="Horn Ross, Pamela L" uniqKey="Horn Ross P" first="Pamela L." last="Horn-Ross">Pamela L. Horn-Ross</name>
<affiliation><nlm:aff id="aff20"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kirsh, Vicki A" sort="Kirsh, Vicki A" uniqKey="Kirsh V" first="Vicki A." last="Kirsh">Vicki A. Kirsh</name>
<affiliation><nlm:aff id="aff21"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff22"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Linet, Martha S" sort="Linet, Martha S" uniqKey="Linet M" first="Martha S." last="Linet">Martha S. Linet</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Macinnis, Robert J" sort="Macinnis, Robert J" uniqKey="Macinnis R" first="Robert J." last="Macinnis">Robert J. Macinnis</name>
<affiliation><nlm:aff id="aff18"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff19"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Orsini, Nicola" sort="Orsini, Nicola" uniqKey="Orsini N" first="Nicola" last="Orsini">Nicola Orsini</name>
<affiliation><nlm:aff id="aff4"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Park, Yikyung" sort="Park, Yikyung" uniqKey="Park Y" first="Yikyung" last="Park">Yikyung Park</name>
<affiliation><nlm:aff id="aff23"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Patel, Alpa V" sort="Patel, Alpa V" uniqKey="Patel A" first="Alpa V." last="Patel">Alpa V. Patel</name>
<affiliation><nlm:aff id="aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Purdue, Mark P" sort="Purdue, Mark P" uniqKey="Purdue M" first="Mark P." last="Purdue">Mark P. Purdue</name>
<affiliation><nlm:aff id="aff24"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Riboli, Elio" sort="Riboli, Elio" uniqKey="Riboli E" first="Elio" last="Riboli">Elio Riboli</name>
<affiliation><nlm:aff id="aff25"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Robien, Kimberly" sort="Robien, Kimberly" uniqKey="Robien K" first="Kimberly" last="Robien">Kimberly Robien</name>
<affiliation><nlm:aff id="aff26"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rohan, Thomas" sort="Rohan, Thomas" uniqKey="Rohan T" first="Thomas" last="Rohan">Thomas Rohan</name>
<affiliation><nlm:aff id="aff27"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Sandler, Dale P" sort="Sandler, Dale P" uniqKey="Sandler D" first="Dale P." last="Sandler">Dale P. Sandler</name>
<affiliation><nlm:aff id="aff14"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Schairer, Catherine" sort="Schairer, Catherine" uniqKey="Schairer C" first="Catherine" last="Schairer">Catherine Schairer</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Schneider, Arthur B" sort="Schneider, Arthur B" uniqKey="Schneider A" first="Arthur B." last="Schneider">Arthur B. Schneider</name>
<affiliation><nlm:aff id="aff28"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Sesso, Howard D" sort="Sesso, Howard D" uniqKey="Sesso H" first="Howard D." last="Sesso">Howard D. Sesso</name>
<affiliation><nlm:aff id="aff7"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff11"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff16"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Shu, Xiao Ou" sort="Shu, Xiao Ou" uniqKey="Shu X" first="Xiao-Ou" last="Shu">Xiao-Ou Shu</name>
<affiliation><nlm:aff id="aff29"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Singh, Pramil N" sort="Singh, Pramil N" uniqKey="Singh P" first="Pramil N." last="Singh">Pramil N. Singh</name>
<affiliation><nlm:aff id="aff30"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Van Den Brandt, Piet A" sort="Van Den Brandt, Piet A" uniqKey="Van Den Brandt P" first="Piet A." last="Van Den Brandt">Piet A. Van Den Brandt</name>
<affiliation><nlm:aff id="aff31"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ward, Elizabeth" sort="Ward, Elizabeth" uniqKey="Ward E" first="Elizabeth" last="Ward">Elizabeth Ward</name>
<affiliation><nlm:aff id="aff32"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name>
<affiliation><nlm:aff id="aff6"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff33"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff34"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff35"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="White, Emily" sort="White, Emily" uniqKey="White E" first="Emily" last="White">Emily White</name>
<affiliation><nlm:aff id="aff36"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff37"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Xiang, Yong Bing" sort="Xiang, Yong Bing" uniqKey="Xiang Y" first="Yong-Bing" last="Xiang">Yong-Bing Xiang</name>
<affiliation><nlm:aff id="aff15"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Zeleniuch Jacquotte, Anne" sort="Zeleniuch Jacquotte, Anne" uniqKey="Zeleniuch Jacquotte A" first="Anne" last="Zeleniuch-Jacquotte">Anne Zeleniuch-Jacquotte</name>
<affiliation><nlm:aff id="aff38"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Zheng, Wei" sort="Zheng, Wei" uniqKey="Zheng W" first="Wei" last="Zheng">Wei Zheng</name>
<affiliation><nlm:aff id="aff29"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hartge, Patricia" sort="Hartge, Patricia" uniqKey="Hartge P" first="Patricia" last="Hartge">Patricia Hartge</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Berrington De Gonzalez, Amy" sort="Berrington De Gonzalez, Amy" uniqKey="Berrington De Gonzalez A" first="Amy" last="Berrington De González">Amy Berrington De González</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Thyroid</title>
<idno type="ISSN">1050-7256</idno>
<idno type="eISSN">1557-9077</idno>
<imprint><date when="2016">2016</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p><bold><italic>Background:</italic>
</bold>
 Greater height and body mass index (BMI) have been associated with an increased risk of thyroid cancer, particularly papillary carcinoma, the most common and least aggressive subtype. Few studies have evaluated these associations in relation to other, more aggressive histologic types or thyroid cancer-specific mortality.</p>
<p><bold><italic>Methods:</italic>
</bold>
 This large pooled analysis of 22 prospective studies (833,176 men and 1,260,871 women) investigated thyroid cancer incidence associated with greater height, BMI at baseline and young adulthood, and adulthood BMI gain (difference between young-adult and baseline BMI), overall and separately by sex and histological subtype using multivariable Cox proportional hazards regression models. Associations with thyroid cancer mortality were investigated in a subset of cohorts (578,922 men and 774,373 women) that contributed cause of death information.</p>
<p><bold><italic>Results:</italic>
</bold>
 During follow-up, 2996 incident thyroid cancers and 104 thyroid cancer deaths were identified. All anthropometric factors were positively associated with thyroid cancer incidence: hazard ratios (HR) [confidence intervals (CIs)] for height (per 5 cm) = 1.07 [1.04–1.10], BMI (per 5 kg/m<sup>2</sup>
) = 1.06 [1.02–1.10], waist circumference (per 5 cm) = 1.03 [1.01–1.05], young-adult BMI (per 5 kg/m<sup>2</sup>
) = 1.13 [1.02–1.25], and adulthood BMI gain (per 5 kg/m<sup>2</sup>
) = 1.07 [1.00–1.15]. Associations for baseline BMI and waist circumference were attenuated after mutual adjustment. Baseline BMI was more strongly associated with risk in men compared with women (<italic>p</italic>
 = 0.04). Positive associations were observed for papillary, follicular, and anaplastic, but not medullary, thyroid carcinomas. Similar, but stronger, associations were observed for thyroid cancer mortality.</p>
<p><bold><italic>Conclusion:</italic>
</bold>
 The results suggest that greater height and excess adiposity throughout adulthood are associated with higher incidence of most major types of thyroid cancer, including the least common but most aggressive form, anaplastic carcinoma, and higher thyroid cancer mortality. Potential underlying biological mechanisms should be explored in future studies.</p>
</div>
</front>
</TEI>
</pmc>
<pubmed><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Anthropometric Factors and Thyroid Cancer Risk by Histological Subtype: Pooled Analysis of 22 Prospective Studies.</title>
<author><name sortKey="Kitahara, Cari M" sort="Kitahara, Cari M" uniqKey="Kitahara C" first="Cari M" last="Kitahara">Cari M. Kitahara</name>
<affiliation wicri:level="2"><nlm:affiliation>1 Division of Cancer Epidemiology and Genetics; National Cancer Institute , Rockville, Maryland.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>1 Division of Cancer Epidemiology and Genetics; National Cancer Institute , Rockville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Mccullough, Marjorie L" sort="Mccullough, Marjorie L" uniqKey="Mccullough M" first="Marjorie L" last="Mccullough">Marjorie L. Mccullough</name>
<affiliation wicri:level="1"><nlm:affiliation>2 Epidemiology Research Program, American Cancer Society , Atlanta, Georgia .</nlm:affiliation>
<country xml:lang="fr">Géorgie (pays)</country>
<wicri:regionArea>2 Epidemiology Research Program, American Cancer Society , Atlanta</wicri:regionArea>
<wicri:noRegion>Atlanta</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Franceschi, Silvia" sort="Franceschi, Silvia" uniqKey="Franceschi S" first="Silvia" last="Franceschi">Silvia Franceschi</name>
<affiliation wicri:level="3"><nlm:affiliation>3 International Agency for Research on Cancer , Lyon, France .</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>3 International Agency for Research on Cancer , Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Rinaldi, Sabina" sort="Rinaldi, Sabina" uniqKey="Rinaldi S" first="Sabina" last="Rinaldi">Sabina Rinaldi</name>
<affiliation wicri:level="3"><nlm:affiliation>3 International Agency for Research on Cancer , Lyon, France .</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>3 International Agency for Research on Cancer , Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Wolk, Alicja" sort="Wolk, Alicja" uniqKey="Wolk A" first="Alicja" last="Wolk">Alicja Wolk</name>
<affiliation wicri:level="3"><nlm:affiliation>4 Division of Nutritional Epidemiology, Institute of Environmental Medicine; Karolinska Institutet , Stockholm, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>4 Division of Nutritional Epidemiology, Institute of Environmental Medicine; Karolinska Institutet , Stockholm</wicri:regionArea>
<placeName><settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Neta, Gila" sort="Neta, Gila" uniqKey="Neta G" first="Gila" last="Neta">Gila Neta</name>
<affiliation wicri:level="2"><nlm:affiliation>5 Division of Cancer Control and Population Sciences; National Cancer Institute , Rockville, Maryland.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>5 Division of Cancer Control and Population Sciences; National Cancer Institute , Rockville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Olov Adami, Hans" sort="Olov Adami, Hans" uniqKey="Olov Adami H" first="Hans" last="Olov Adami">Hans Olov Adami</name>
<affiliation wicri:level="3"><nlm:affiliation>6 Department of Medical Epidemiology and Biostatistics; Karolinska Institutet , Stockholm, Sweden .</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>6 Department of Medical Epidemiology and Biostatistics; Karolinska Institutet , Stockholm</wicri:regionArea>
<placeName><settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Anderson, Kristin" sort="Anderson, Kristin" uniqKey="Anderson K" first="Kristin" last="Anderson">Kristin Anderson</name>
<affiliation wicri:level="2"><nlm:affiliation>8 Division of Epidemiology and Community Health, School of Public Health; University of Minnesota , Minneapolis, Minnesota.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Minnesota</region>
</placeName>
<wicri:cityArea>8 Division of Epidemiology and Community Health, School of Public Health; University of Minnesota , Minneapolis</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Andreotti, Gabriella" sort="Andreotti, Gabriella" uniqKey="Andreotti G" first="Gabriella" last="Andreotti">Gabriella Andreotti</name>
<affiliation wicri:level="2"><nlm:affiliation>1 Division of Cancer Epidemiology and Genetics; National Cancer Institute , Rockville, Maryland.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>1 Division of Cancer Epidemiology and Genetics; National Cancer Institute , Rockville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Beane Freeman, Laura E" sort="Beane Freeman, Laura E" uniqKey="Beane Freeman L" first="Laura E" last="Beane Freeman">Laura E. Beane Freeman</name>
<affiliation wicri:level="2"><nlm:affiliation>1 Division of Cancer Epidemiology and Genetics; National Cancer Institute , Rockville, Maryland.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>1 Division of Cancer Epidemiology and Genetics; National Cancer Institute , Rockville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Bernstein, Leslie" sort="Bernstein, Leslie" uniqKey="Bernstein L" first="Leslie" last="Bernstein">Leslie Bernstein</name>
<affiliation wicri:level="2"><nlm:affiliation>10 Division of Cancer Etiology, Department of Population Sciences, Beckman Research Institute , City of Hope, Duarte, California.</nlm:affiliation>
<country>États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>10 Division of Cancer Etiology, Department of Population Sciences, Beckman Research Institute , City of Hope, Duarte</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Buring, Julie E" sort="Buring, Julie E" uniqKey="Buring J" first="Julie E" last="Buring">Julie E. Buring</name>
<affiliation wicri:level="2"><nlm:affiliation>7 Department of Epidemiology, Harvard School of Public Health , Boston, Massachusetts.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>7 Department of Epidemiology, Harvard School of Public Health , Boston</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Clavel Chapelon, Francoise" sort="Clavel Chapelon, Francoise" uniqKey="Clavel Chapelon F" first="Francoise" last="Clavel-Chapelon">Francoise Clavel-Chapelon</name>
<affiliation wicri:level="1"><nlm:affiliation>12 Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Villejuif, France Paris South University , UMRS Inserm 1018 Team 9, Villejuif, France .</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>12 Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Villejuif, France Paris South University , UMRS Inserm 1018 Team 9, Villejuif</wicri:regionArea>
<wicri:noRegion>Villejuif</wicri:noRegion>
<wicri:noRegion>Villejuif</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="De Roo, Lisa A" sort="De Roo, Lisa A" uniqKey="De Roo L" first="Lisa A" last="De Roo">Lisa A. De Roo</name>
<affiliation wicri:level="1"><nlm:affiliation>13 Department of Global Public Health and Primary Care, University of Bergen , Bergen, Norway .</nlm:affiliation>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea>13 Department of Global Public Health and Primary Care, University of Bergen , Bergen</wicri:regionArea>
<wicri:noRegion>Bergen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gao, Yu Tang" sort="Gao, Yu Tang" uniqKey="Gao Y" first="Yu-Tang" last="Gao">Yu-Tang Gao</name>
<affiliation wicri:level="1"><nlm:affiliation>15 Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine , Shanghai, China .</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>15 Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine , Shanghai</wicri:regionArea>
<wicri:noRegion>Shanghai</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gaziano, J Michael" sort="Gaziano, J Michael" uniqKey="Gaziano J" first="J Michael" last="Gaziano">J Michael Gaziano</name>
<affiliation wicri:level="2"><nlm:affiliation>11 Division of Preventive Medicine, Department of Medicine; Brigham and Women's Hospital , Boston, Massachusetts.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>11 Division of Preventive Medicine, Department of Medicine; Brigham and Women's Hospital , Boston</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Giles, Graham G" sort="Giles, Graham G" uniqKey="Giles G" first="Graham G" last="Giles">Graham G. Giles</name>
<affiliation wicri:level="3"><nlm:affiliation>18 Cancer Epidemiology Centre, Cancer Council Victoria , Melbourne, Australia .</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>18 Cancer Epidemiology Centre, Cancer Council Victoria , Melbourne</wicri:regionArea>
<placeName><settlement type="city">Melbourne</settlement>
<region type="état">Victoria (État)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="H Kansson, Niclas" sort="H Kansson, Niclas" uniqKey="H Kansson N" first="Niclas" last="H Kansson">Niclas H Kansson</name>
<affiliation wicri:level="3"><nlm:affiliation>4 Division of Nutritional Epidemiology, Institute of Environmental Medicine; Karolinska Institutet , Stockholm, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>4 Division of Nutritional Epidemiology, Institute of Environmental Medicine; Karolinska Institutet , Stockholm</wicri:regionArea>
<placeName><settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Horn Ross, Pamela L" sort="Horn Ross, Pamela L" uniqKey="Horn Ross P" first="Pamela L" last="Horn-Ross">Pamela L. Horn-Ross</name>
<affiliation wicri:level="2"><nlm:affiliation>20 Cancer Prevention Institute of California , Fremont, California.</nlm:affiliation>
<country>États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>20 Cancer Prevention Institute of California , Fremont</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Kirsh, Vicki A" sort="Kirsh, Vicki A" uniqKey="Kirsh V" first="Vicki A" last="Kirsh">Vicki A. Kirsh</name>
<affiliation wicri:level="1"><nlm:affiliation>21 Prevention and Cancer Control, Cancer Care Ontario , Toronto, Canada .</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>21 Prevention and Cancer Control, Cancer Care Ontario , Toronto</wicri:regionArea>
<wicri:noRegion>Toronto</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Linet, Martha S" sort="Linet, Martha S" uniqKey="Linet M" first="Martha S" last="Linet">Martha S. Linet</name>
<affiliation wicri:level="2"><nlm:affiliation>1 Division of Cancer Epidemiology and Genetics; National Cancer Institute , Rockville, Maryland.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>1 Division of Cancer Epidemiology and Genetics; National Cancer Institute , Rockville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Macinnis, Robert J" sort="Macinnis, Robert J" uniqKey="Macinnis R" first="Robert J" last="Macinnis">Robert J. Macinnis</name>
<affiliation wicri:level="3"><nlm:affiliation>18 Cancer Epidemiology Centre, Cancer Council Victoria , Melbourne, Australia .</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>18 Cancer Epidemiology Centre, Cancer Council Victoria , Melbourne</wicri:regionArea>
<placeName><settlement type="city">Melbourne</settlement>
<region type="état">Victoria (État)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Orsini, Nicola" sort="Orsini, Nicola" uniqKey="Orsini N" first="Nicola" last="Orsini">Nicola Orsini</name>
<affiliation wicri:level="3"><nlm:affiliation>4 Division of Nutritional Epidemiology, Institute of Environmental Medicine; Karolinska Institutet , Stockholm, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>4 Division of Nutritional Epidemiology, Institute of Environmental Medicine; Karolinska Institutet , Stockholm</wicri:regionArea>
<placeName><settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Park, Yikyung" sort="Park, Yikyung" uniqKey="Park Y" first="Yikyung" last="Park">Yikyung Park</name>
<affiliation wicri:level="2"><nlm:affiliation>23 Division of Public Health Sciences, Washington University School of Medicine in St. Louis , St. Louis, Missouri.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Missouri (État)</region>
</placeName>
<wicri:cityArea>23 Division of Public Health Sciences, Washington University School of Medicine in St. Louis , St. Louis</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Patel, Alpa V" sort="Patel, Alpa V" uniqKey="Patel A" first="Alpa V" last="Patel">Alpa V. Patel</name>
<affiliation wicri:level="1"><nlm:affiliation>2 Epidemiology Research Program, American Cancer Society , Atlanta, Georgia .</nlm:affiliation>
<country xml:lang="fr">Géorgie (pays)</country>
<wicri:regionArea>2 Epidemiology Research Program, American Cancer Society , Atlanta</wicri:regionArea>
<wicri:noRegion>Atlanta</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Purdue, Mark P" sort="Purdue, Mark P" uniqKey="Purdue M" first="Mark P" last="Purdue">Mark P. Purdue</name>
<affiliation wicri:level="1"><nlm:affiliation>24 Ontario Institute for Cancer Research , Toronto, Canada .</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>24 Ontario Institute for Cancer Research , Toronto</wicri:regionArea>
<wicri:noRegion>Toronto</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Riboli, Elio" sort="Riboli, Elio" uniqKey="Riboli E" first="Elio" last="Riboli">Elio Riboli</name>
<affiliation wicri:level="3"><nlm:affiliation>25 Imperial School of Public Health, Imperial College London , London, United Kingdom .</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>25 Imperial School of Public Health, Imperial College London , London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Robien, Kimberly" sort="Robien, Kimberly" uniqKey="Robien K" first="Kimberly" last="Robien">Kimberly Robien</name>
<affiliation wicri:level="2"><nlm:affiliation>26 Department of Exercise and Nutrition Sciences, Milken Institute School of Public Health, George Washington University , Washington, DC.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">District de Columbia</region>
</placeName>
<wicri:cityArea>26 Department of Exercise and Nutrition Sciences, Milken Institute School of Public Health, George Washington University , Washington</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Rohan, Thomas" sort="Rohan, Thomas" uniqKey="Rohan T" first="Thomas" last="Rohan">Thomas Rohan</name>
<affiliation wicri:level="2"><nlm:affiliation>27 Department of Epidemiology and Population Health, Albert Einstein College of Medicine , Bronx, New York.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">État de New York</region>
</placeName>
<wicri:cityArea>27 Department of Epidemiology and Population Health, Albert Einstein College of Medicine , Bronx</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Sandler, Dale P" sort="Sandler, Dale P" uniqKey="Sandler D" first="Dale P" last="Sandler">Dale P. Sandler</name>
<affiliation wicri:level="2"><nlm:affiliation>14 Epidemiology Branch, National Institute of Environmental Health Sciences , Research Triangle Park, North Carolina.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
<wicri:cityArea>14 Epidemiology Branch, National Institute of Environmental Health Sciences , Research Triangle Park</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Schairer, Catherine" sort="Schairer, Catherine" uniqKey="Schairer C" first="Catherine" last="Schairer">Catherine Schairer</name>
<affiliation wicri:level="2"><nlm:affiliation>1 Division of Cancer Epidemiology and Genetics; National Cancer Institute , Rockville, Maryland.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>1 Division of Cancer Epidemiology and Genetics; National Cancer Institute , Rockville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Schneider, Arthur B" sort="Schneider, Arthur B" uniqKey="Schneider A" first="Arthur B" last="Schneider">Arthur B. Schneider</name>
<affiliation wicri:level="2"><nlm:affiliation>28 Section of Endocrinology, Diabetes and Metabolism, University of Illinois at Chicago , Chicago, Illinois.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Illinois</region>
</placeName>
<wicri:cityArea>28 Section of Endocrinology, Diabetes and Metabolism, University of Illinois at Chicago , Chicago</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Sesso, Howard D" sort="Sesso, Howard D" uniqKey="Sesso H" first="Howard D" last="Sesso">Howard D. Sesso</name>
<affiliation wicri:level="2"><nlm:affiliation>7 Department of Epidemiology, Harvard School of Public Health , Boston, Massachusetts.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>7 Department of Epidemiology, Harvard School of Public Health , Boston</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Shu, Xiao Ou" sort="Shu, Xiao Ou" uniqKey="Shu X" first="Xiao-Ou" last="Shu">Xiao-Ou Shu</name>
<affiliation wicri:level="2"><nlm:affiliation>29 Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine , Nashville, Tennessee.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Tennessee</region>
</placeName>
<wicri:cityArea>29 Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine , Nashville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Singh, Pramil N" sort="Singh, Pramil N" uniqKey="Singh P" first="Pramil N" last="Singh">Pramil N. Singh</name>
<affiliation wicri:level="2"><nlm:affiliation>30 Center for Health Research, School of Public Health, Loma Linda University , Loma Linda, California.</nlm:affiliation>
<country>États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>30 Center for Health Research, School of Public Health, Loma Linda University , Loma Linda</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Van Den Brandt, Piet A" sort="Van Den Brandt, Piet A" uniqKey="Van Den Brandt P" first="Piet A" last="Van Den Brandt">Piet A. Van Den Brandt</name>
<affiliation wicri:level="1"><nlm:affiliation>31 Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University , Maastricht, Netherlands .</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>31 Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University , Maastricht</wicri:regionArea>
<wicri:noRegion>Maastricht</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ward, Elizabeth" sort="Ward, Elizabeth" uniqKey="Ward E" first="Elizabeth" last="Ward">Elizabeth Ward</name>
<affiliation wicri:level="1"><nlm:affiliation>32 Intramural Research, American Cancer Society , Atlanta, Georgia .</nlm:affiliation>
<country xml:lang="fr">Géorgie (pays)</country>
<wicri:regionArea>32 Intramural Research, American Cancer Society , Atlanta</wicri:regionArea>
<wicri:noRegion>Atlanta</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name>
<affiliation wicri:level="3"><nlm:affiliation>6 Department of Medical Epidemiology and Biostatistics; Karolinska Institutet , Stockholm, Sweden .</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>6 Department of Medical Epidemiology and Biostatistics; Karolinska Institutet , Stockholm</wicri:regionArea>
<placeName><settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="White, Emily" sort="White, Emily" uniqKey="White E" first="Emily" last="White">Emily White</name>
<affiliation wicri:level="2"><nlm:affiliation>36 Public Health Services Division, Fred Hutchinson Cancer Research Center , Seattle, Washington.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Washington (État)</region>
</placeName>
<wicri:cityArea>36 Public Health Services Division, Fred Hutchinson Cancer Research Center , Seattle</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Xiang, Yong Bing" sort="Xiang, Yong Bing" uniqKey="Xiang Y" first="Yong-Bing" last="Xiang">Yong-Bing Xiang</name>
<affiliation wicri:level="1"><nlm:affiliation>15 Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine , Shanghai, China .</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>15 Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine , Shanghai</wicri:regionArea>
<wicri:noRegion>Shanghai</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zeleniuch Jacquotte, Anne" sort="Zeleniuch Jacquotte, Anne" uniqKey="Zeleniuch Jacquotte A" first="Anne" last="Zeleniuch-Jacquotte">Anne Zeleniuch-Jacquotte</name>
<affiliation wicri:level="2"><nlm:affiliation>38 Division of Epidemiology, Department of Population Health and NYU Cancer Institute, NYU School of Medicine , New York, New York.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">État de New York</region>
</placeName>
<wicri:cityArea>38 Division of Epidemiology, Department of Population Health and NYU Cancer Institute, NYU School of Medicine , New York</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Zheng, Wei" sort="Zheng, Wei" uniqKey="Zheng W" first="Wei" last="Zheng">Wei Zheng</name>
<affiliation wicri:level="2"><nlm:affiliation>29 Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine , Nashville, Tennessee.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Tennessee</region>
</placeName>
<wicri:cityArea>29 Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine , Nashville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Hartge, Patricia" sort="Hartge, Patricia" uniqKey="Hartge P" first="Patricia" last="Hartge">Patricia Hartge</name>
<affiliation wicri:level="2"><nlm:affiliation>1 Division of Cancer Epidemiology and Genetics; National Cancer Institute , Rockville, Maryland.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>1 Division of Cancer Epidemiology and Genetics; National Cancer Institute , Rockville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Berrington De Gonzalez, Amy" sort="Berrington De Gonzalez, Amy" uniqKey="Berrington De Gonzalez A" first="Amy" last="Berrington De González">Amy Berrington De González</name>
<affiliation wicri:level="2"><nlm:affiliation>1 Division of Cancer Epidemiology and Genetics; National Cancer Institute , Rockville, Maryland.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>1 Division of Cancer Epidemiology and Genetics; National Cancer Institute , Rockville</wicri:cityArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2016">2016</date>
<idno type="RBID">pubmed:26756356</idno>
<idno type="pmid">26756356</idno>
<idno type="doi">10.1089/thy.2015.0319</idno>
<idno type="wicri:Area/PubMed/Corpus">002307</idno>
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<idno type="wicri:Area/PubMed/Curation">002281</idno>
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<idno type="wicri:Area/PubMed/Checkpoint">002281</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002281</idno>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Anthropometric Factors and Thyroid Cancer Risk by Histological Subtype: Pooled Analysis of 22 Prospective Studies.</title>
<author><name sortKey="Kitahara, Cari M" sort="Kitahara, Cari M" uniqKey="Kitahara C" first="Cari M" last="Kitahara">Cari M. Kitahara</name>
<affiliation wicri:level="2"><nlm:affiliation>1 Division of Cancer Epidemiology and Genetics; National Cancer Institute , Rockville, Maryland.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>1 Division of Cancer Epidemiology and Genetics; National Cancer Institute , Rockville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Mccullough, Marjorie L" sort="Mccullough, Marjorie L" uniqKey="Mccullough M" first="Marjorie L" last="Mccullough">Marjorie L. Mccullough</name>
<affiliation wicri:level="1"><nlm:affiliation>2 Epidemiology Research Program, American Cancer Society , Atlanta, Georgia .</nlm:affiliation>
<country xml:lang="fr">Géorgie (pays)</country>
<wicri:regionArea>2 Epidemiology Research Program, American Cancer Society , Atlanta</wicri:regionArea>
<wicri:noRegion>Atlanta</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Franceschi, Silvia" sort="Franceschi, Silvia" uniqKey="Franceschi S" first="Silvia" last="Franceschi">Silvia Franceschi</name>
<affiliation wicri:level="3"><nlm:affiliation>3 International Agency for Research on Cancer , Lyon, France .</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>3 International Agency for Research on Cancer , Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Rinaldi, Sabina" sort="Rinaldi, Sabina" uniqKey="Rinaldi S" first="Sabina" last="Rinaldi">Sabina Rinaldi</name>
<affiliation wicri:level="3"><nlm:affiliation>3 International Agency for Research on Cancer , Lyon, France .</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>3 International Agency for Research on Cancer , Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Wolk, Alicja" sort="Wolk, Alicja" uniqKey="Wolk A" first="Alicja" last="Wolk">Alicja Wolk</name>
<affiliation wicri:level="3"><nlm:affiliation>4 Division of Nutritional Epidemiology, Institute of Environmental Medicine; Karolinska Institutet , Stockholm, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>4 Division of Nutritional Epidemiology, Institute of Environmental Medicine; Karolinska Institutet , Stockholm</wicri:regionArea>
<placeName><settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Neta, Gila" sort="Neta, Gila" uniqKey="Neta G" first="Gila" last="Neta">Gila Neta</name>
<affiliation wicri:level="2"><nlm:affiliation>5 Division of Cancer Control and Population Sciences; National Cancer Institute , Rockville, Maryland.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>5 Division of Cancer Control and Population Sciences; National Cancer Institute , Rockville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Olov Adami, Hans" sort="Olov Adami, Hans" uniqKey="Olov Adami H" first="Hans" last="Olov Adami">Hans Olov Adami</name>
<affiliation wicri:level="3"><nlm:affiliation>6 Department of Medical Epidemiology and Biostatistics; Karolinska Institutet , Stockholm, Sweden .</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>6 Department of Medical Epidemiology and Biostatistics; Karolinska Institutet , Stockholm</wicri:regionArea>
<placeName><settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Anderson, Kristin" sort="Anderson, Kristin" uniqKey="Anderson K" first="Kristin" last="Anderson">Kristin Anderson</name>
<affiliation wicri:level="2"><nlm:affiliation>8 Division of Epidemiology and Community Health, School of Public Health; University of Minnesota , Minneapolis, Minnesota.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Minnesota</region>
</placeName>
<wicri:cityArea>8 Division of Epidemiology and Community Health, School of Public Health; University of Minnesota , Minneapolis</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Andreotti, Gabriella" sort="Andreotti, Gabriella" uniqKey="Andreotti G" first="Gabriella" last="Andreotti">Gabriella Andreotti</name>
<affiliation wicri:level="2"><nlm:affiliation>1 Division of Cancer Epidemiology and Genetics; National Cancer Institute , Rockville, Maryland.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>1 Division of Cancer Epidemiology and Genetics; National Cancer Institute , Rockville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Beane Freeman, Laura E" sort="Beane Freeman, Laura E" uniqKey="Beane Freeman L" first="Laura E" last="Beane Freeman">Laura E. Beane Freeman</name>
<affiliation wicri:level="2"><nlm:affiliation>1 Division of Cancer Epidemiology and Genetics; National Cancer Institute , Rockville, Maryland.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>1 Division of Cancer Epidemiology and Genetics; National Cancer Institute , Rockville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Bernstein, Leslie" sort="Bernstein, Leslie" uniqKey="Bernstein L" first="Leslie" last="Bernstein">Leslie Bernstein</name>
<affiliation wicri:level="2"><nlm:affiliation>10 Division of Cancer Etiology, Department of Population Sciences, Beckman Research Institute , City of Hope, Duarte, California.</nlm:affiliation>
<country>États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>10 Division of Cancer Etiology, Department of Population Sciences, Beckman Research Institute , City of Hope, Duarte</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Buring, Julie E" sort="Buring, Julie E" uniqKey="Buring J" first="Julie E" last="Buring">Julie E. Buring</name>
<affiliation wicri:level="2"><nlm:affiliation>7 Department of Epidemiology, Harvard School of Public Health , Boston, Massachusetts.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>7 Department of Epidemiology, Harvard School of Public Health , Boston</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Clavel Chapelon, Francoise" sort="Clavel Chapelon, Francoise" uniqKey="Clavel Chapelon F" first="Francoise" last="Clavel-Chapelon">Francoise Clavel-Chapelon</name>
<affiliation wicri:level="1"><nlm:affiliation>12 Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Villejuif, France Paris South University , UMRS Inserm 1018 Team 9, Villejuif, France .</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>12 Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Villejuif, France Paris South University , UMRS Inserm 1018 Team 9, Villejuif</wicri:regionArea>
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<author><name sortKey="Gao, Yu Tang" sort="Gao, Yu Tang" uniqKey="Gao Y" first="Yu-Tang" last="Gao">Yu-Tang Gao</name>
<affiliation wicri:level="1"><nlm:affiliation>15 Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine , Shanghai, China .</nlm:affiliation>
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<wicri:regionArea>15 Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine , Shanghai</wicri:regionArea>
<wicri:noRegion>Shanghai</wicri:noRegion>
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</author>
<author><name sortKey="Gaziano, J Michael" sort="Gaziano, J Michael" uniqKey="Gaziano J" first="J Michael" last="Gaziano">J Michael Gaziano</name>
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<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>11 Division of Preventive Medicine, Department of Medicine; Brigham and Women's Hospital , Boston</wicri:cityArea>
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</author>
<author><name sortKey="Giles, Graham G" sort="Giles, Graham G" uniqKey="Giles G" first="Graham G" last="Giles">Graham G. Giles</name>
<affiliation wicri:level="3"><nlm:affiliation>18 Cancer Epidemiology Centre, Cancer Council Victoria , Melbourne, Australia .</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>18 Cancer Epidemiology Centre, Cancer Council Victoria , Melbourne</wicri:regionArea>
<placeName><settlement type="city">Melbourne</settlement>
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</author>
<author><name sortKey="H Kansson, Niclas" sort="H Kansson, Niclas" uniqKey="H Kansson N" first="Niclas" last="H Kansson">Niclas H Kansson</name>
<affiliation wicri:level="3"><nlm:affiliation>4 Division of Nutritional Epidemiology, Institute of Environmental Medicine; Karolinska Institutet , Stockholm, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>4 Division of Nutritional Epidemiology, Institute of Environmental Medicine; Karolinska Institutet , Stockholm</wicri:regionArea>
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<author><name sortKey="Horn Ross, Pamela L" sort="Horn Ross, Pamela L" uniqKey="Horn Ross P" first="Pamela L" last="Horn-Ross">Pamela L. Horn-Ross</name>
<affiliation wicri:level="2"><nlm:affiliation>20 Cancer Prevention Institute of California , Fremont, California.</nlm:affiliation>
<country>États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>20 Cancer Prevention Institute of California , Fremont</wicri:cityArea>
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<author><name sortKey="Kirsh, Vicki A" sort="Kirsh, Vicki A" uniqKey="Kirsh V" first="Vicki A" last="Kirsh">Vicki A. Kirsh</name>
<affiliation wicri:level="1"><nlm:affiliation>21 Prevention and Cancer Control, Cancer Care Ontario , Toronto, Canada .</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>21 Prevention and Cancer Control, Cancer Care Ontario , Toronto</wicri:regionArea>
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<author><name sortKey="Linet, Martha S" sort="Linet, Martha S" uniqKey="Linet M" first="Martha S" last="Linet">Martha S. Linet</name>
<affiliation wicri:level="2"><nlm:affiliation>1 Division of Cancer Epidemiology and Genetics; National Cancer Institute , Rockville, Maryland.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>1 Division of Cancer Epidemiology and Genetics; National Cancer Institute , Rockville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Macinnis, Robert J" sort="Macinnis, Robert J" uniqKey="Macinnis R" first="Robert J" last="Macinnis">Robert J. Macinnis</name>
<affiliation wicri:level="3"><nlm:affiliation>18 Cancer Epidemiology Centre, Cancer Council Victoria , Melbourne, Australia .</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>18 Cancer Epidemiology Centre, Cancer Council Victoria , Melbourne</wicri:regionArea>
<placeName><settlement type="city">Melbourne</settlement>
<region type="état">Victoria (État)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Orsini, Nicola" sort="Orsini, Nicola" uniqKey="Orsini N" first="Nicola" last="Orsini">Nicola Orsini</name>
<affiliation wicri:level="3"><nlm:affiliation>4 Division of Nutritional Epidemiology, Institute of Environmental Medicine; Karolinska Institutet , Stockholm, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>4 Division of Nutritional Epidemiology, Institute of Environmental Medicine; Karolinska Institutet , Stockholm</wicri:regionArea>
<placeName><settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Park, Yikyung" sort="Park, Yikyung" uniqKey="Park Y" first="Yikyung" last="Park">Yikyung Park</name>
<affiliation wicri:level="2"><nlm:affiliation>23 Division of Public Health Sciences, Washington University School of Medicine in St. Louis , St. Louis, Missouri.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Missouri (État)</region>
</placeName>
<wicri:cityArea>23 Division of Public Health Sciences, Washington University School of Medicine in St. Louis , St. Louis</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Patel, Alpa V" sort="Patel, Alpa V" uniqKey="Patel A" first="Alpa V" last="Patel">Alpa V. Patel</name>
<affiliation wicri:level="1"><nlm:affiliation>2 Epidemiology Research Program, American Cancer Society , Atlanta, Georgia .</nlm:affiliation>
<country xml:lang="fr">Géorgie (pays)</country>
<wicri:regionArea>2 Epidemiology Research Program, American Cancer Society , Atlanta</wicri:regionArea>
<wicri:noRegion>Atlanta</wicri:noRegion>
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</author>
<author><name sortKey="Purdue, Mark P" sort="Purdue, Mark P" uniqKey="Purdue M" first="Mark P" last="Purdue">Mark P. Purdue</name>
<affiliation wicri:level="1"><nlm:affiliation>24 Ontario Institute for Cancer Research , Toronto, Canada .</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>24 Ontario Institute for Cancer Research , Toronto</wicri:regionArea>
<wicri:noRegion>Toronto</wicri:noRegion>
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<author><name sortKey="Riboli, Elio" sort="Riboli, Elio" uniqKey="Riboli E" first="Elio" last="Riboli">Elio Riboli</name>
<affiliation wicri:level="3"><nlm:affiliation>25 Imperial School of Public Health, Imperial College London , London, United Kingdom .</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>25 Imperial School of Public Health, Imperial College London , London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Robien, Kimberly" sort="Robien, Kimberly" uniqKey="Robien K" first="Kimberly" last="Robien">Kimberly Robien</name>
<affiliation wicri:level="2"><nlm:affiliation>26 Department of Exercise and Nutrition Sciences, Milken Institute School of Public Health, George Washington University , Washington, DC.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">District de Columbia</region>
</placeName>
<wicri:cityArea>26 Department of Exercise and Nutrition Sciences, Milken Institute School of Public Health, George Washington University , Washington</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Rohan, Thomas" sort="Rohan, Thomas" uniqKey="Rohan T" first="Thomas" last="Rohan">Thomas Rohan</name>
<affiliation wicri:level="2"><nlm:affiliation>27 Department of Epidemiology and Population Health, Albert Einstein College of Medicine , Bronx, New York.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">État de New York</region>
</placeName>
<wicri:cityArea>27 Department of Epidemiology and Population Health, Albert Einstein College of Medicine , Bronx</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Sandler, Dale P" sort="Sandler, Dale P" uniqKey="Sandler D" first="Dale P" last="Sandler">Dale P. Sandler</name>
<affiliation wicri:level="2"><nlm:affiliation>14 Epidemiology Branch, National Institute of Environmental Health Sciences , Research Triangle Park, North Carolina.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
<wicri:cityArea>14 Epidemiology Branch, National Institute of Environmental Health Sciences , Research Triangle Park</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Schairer, Catherine" sort="Schairer, Catherine" uniqKey="Schairer C" first="Catherine" last="Schairer">Catherine Schairer</name>
<affiliation wicri:level="2"><nlm:affiliation>1 Division of Cancer Epidemiology and Genetics; National Cancer Institute , Rockville, Maryland.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>1 Division of Cancer Epidemiology and Genetics; National Cancer Institute , Rockville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Schneider, Arthur B" sort="Schneider, Arthur B" uniqKey="Schneider A" first="Arthur B" last="Schneider">Arthur B. Schneider</name>
<affiliation wicri:level="2"><nlm:affiliation>28 Section of Endocrinology, Diabetes and Metabolism, University of Illinois at Chicago , Chicago, Illinois.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Illinois</region>
</placeName>
<wicri:cityArea>28 Section of Endocrinology, Diabetes and Metabolism, University of Illinois at Chicago , Chicago</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Sesso, Howard D" sort="Sesso, Howard D" uniqKey="Sesso H" first="Howard D" last="Sesso">Howard D. Sesso</name>
<affiliation wicri:level="2"><nlm:affiliation>7 Department of Epidemiology, Harvard School of Public Health , Boston, Massachusetts.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>7 Department of Epidemiology, Harvard School of Public Health , Boston</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Shu, Xiao Ou" sort="Shu, Xiao Ou" uniqKey="Shu X" first="Xiao-Ou" last="Shu">Xiao-Ou Shu</name>
<affiliation wicri:level="2"><nlm:affiliation>29 Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine , Nashville, Tennessee.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Tennessee</region>
</placeName>
<wicri:cityArea>29 Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine , Nashville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Singh, Pramil N" sort="Singh, Pramil N" uniqKey="Singh P" first="Pramil N" last="Singh">Pramil N. Singh</name>
<affiliation wicri:level="2"><nlm:affiliation>30 Center for Health Research, School of Public Health, Loma Linda University , Loma Linda, California.</nlm:affiliation>
<country>États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>30 Center for Health Research, School of Public Health, Loma Linda University , Loma Linda</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Van Den Brandt, Piet A" sort="Van Den Brandt, Piet A" uniqKey="Van Den Brandt P" first="Piet A" last="Van Den Brandt">Piet A. Van Den Brandt</name>
<affiliation wicri:level="1"><nlm:affiliation>31 Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University , Maastricht, Netherlands .</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>31 Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University , Maastricht</wicri:regionArea>
<wicri:noRegion>Maastricht</wicri:noRegion>
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</author>
<author><name sortKey="Ward, Elizabeth" sort="Ward, Elizabeth" uniqKey="Ward E" first="Elizabeth" last="Ward">Elizabeth Ward</name>
<affiliation wicri:level="1"><nlm:affiliation>32 Intramural Research, American Cancer Society , Atlanta, Georgia .</nlm:affiliation>
<country xml:lang="fr">Géorgie (pays)</country>
<wicri:regionArea>32 Intramural Research, American Cancer Society , Atlanta</wicri:regionArea>
<wicri:noRegion>Atlanta</wicri:noRegion>
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<author><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name>
<affiliation wicri:level="3"><nlm:affiliation>6 Department of Medical Epidemiology and Biostatistics; Karolinska Institutet , Stockholm, Sweden .</nlm:affiliation>
<country xml:lang="fr">Suède</country>
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<placeName><settlement type="city">Stockholm</settlement>
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<author><name sortKey="White, Emily" sort="White, Emily" uniqKey="White E" first="Emily" last="White">Emily White</name>
<affiliation wicri:level="2"><nlm:affiliation>36 Public Health Services Division, Fred Hutchinson Cancer Research Center , Seattle, Washington.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Washington (État)</region>
</placeName>
<wicri:cityArea>36 Public Health Services Division, Fred Hutchinson Cancer Research Center , Seattle</wicri:cityArea>
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<author><name sortKey="Xiang, Yong Bing" sort="Xiang, Yong Bing" uniqKey="Xiang Y" first="Yong-Bing" last="Xiang">Yong-Bing Xiang</name>
<affiliation wicri:level="1"><nlm:affiliation>15 Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine , Shanghai, China .</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>15 Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine , Shanghai</wicri:regionArea>
<wicri:noRegion>Shanghai</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zeleniuch Jacquotte, Anne" sort="Zeleniuch Jacquotte, Anne" uniqKey="Zeleniuch Jacquotte A" first="Anne" last="Zeleniuch-Jacquotte">Anne Zeleniuch-Jacquotte</name>
<affiliation wicri:level="2"><nlm:affiliation>38 Division of Epidemiology, Department of Population Health and NYU Cancer Institute, NYU School of Medicine , New York, New York.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">État de New York</region>
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<wicri:cityArea>38 Division of Epidemiology, Department of Population Health and NYU Cancer Institute, NYU School of Medicine , New York</wicri:cityArea>
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</author>
<author><name sortKey="Zheng, Wei" sort="Zheng, Wei" uniqKey="Zheng W" first="Wei" last="Zheng">Wei Zheng</name>
<affiliation wicri:level="2"><nlm:affiliation>29 Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine , Nashville, Tennessee.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Tennessee</region>
</placeName>
<wicri:cityArea>29 Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine , Nashville</wicri:cityArea>
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<author><name sortKey="Hartge, Patricia" sort="Hartge, Patricia" uniqKey="Hartge P" first="Patricia" last="Hartge">Patricia Hartge</name>
<affiliation wicri:level="2"><nlm:affiliation>1 Division of Cancer Epidemiology and Genetics; National Cancer Institute , Rockville, Maryland.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>1 Division of Cancer Epidemiology and Genetics; National Cancer Institute , Rockville</wicri:cityArea>
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</author>
<author><name sortKey="Berrington De Gonzalez, Amy" sort="Berrington De Gonzalez, Amy" uniqKey="Berrington De Gonzalez A" first="Amy" last="Berrington De González">Amy Berrington De González</name>
<affiliation wicri:level="2"><nlm:affiliation>1 Division of Cancer Epidemiology and Genetics; National Cancer Institute , Rockville, Maryland.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>1 Division of Cancer Epidemiology and Genetics; National Cancer Institute , Rockville</wicri:cityArea>
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<series><title level="j">Thyroid : official journal of the American Thyroid Association</title>
<idno type="eISSN">1557-9077</idno>
<imprint><date when="2016" type="published">2016</date>
</imprint>
</series>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Anthropometry</term>
<term>Body Mass Index</term>
<term>Carcinoma (diagnosis)</term>
<term>Carcinoma (mortality)</term>
<term>Carcinoma (physiopathology)</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Proportional Hazards Models</term>
<term>Prospective Studies</term>
<term>Risk Factors</term>
<term>Smoking</term>
<term>Thyroid Neoplasms (diagnosis)</term>
<term>Thyroid Neoplasms (mortality)</term>
<term>Thyroid Neoplasms (physiopathology)</term>
<term>Waist Circumference</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Anthropométrie</term>
<term>Carcinomes (diagnostic)</term>
<term>Carcinomes (mortalité)</term>
<term>Carcinomes (physiopathologie)</term>
<term>Facteurs de risque</term>
<term>Femelle</term>
<term>Humains</term>
<term>Indice de masse corporelle</term>
<term>Modèles de hasards proportionnels</term>
<term>Mâle</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Tabagisme</term>
<term>Tour de taille</term>
<term>Tumeurs de la thyroïde (diagnostic)</term>
<term>Tumeurs de la thyroïde (mortalité)</term>
<term>Tumeurs de la thyroïde (physiopathologie)</term>
<term>Études prospectives</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Carcinoma</term>
<term>Thyroid Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Carcinomes</term>
<term>Tumeurs de la thyroïde</term>
</keywords>
<keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Carcinoma</term>
<term>Thyroid Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Carcinomes</term>
<term>Tumeurs de la thyroïde</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Carcinomes</term>
<term>Tumeurs de la thyroïde</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Carcinoma</term>
<term>Thyroid Neoplasms</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Anthropometry</term>
<term>Body Mass Index</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Proportional Hazards Models</term>
<term>Prospective Studies</term>
<term>Risk Factors</term>
<term>Smoking</term>
<term>Waist Circumference</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Anthropométrie</term>
<term>Facteurs de risque</term>
<term>Femelle</term>
<term>Humains</term>
<term>Indice de masse corporelle</term>
<term>Modèles de hasards proportionnels</term>
<term>Mâle</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Tabagisme</term>
<term>Tour de taille</term>
<term>Études prospectives</term>
</keywords>
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<front><div type="abstract" xml:lang="en">Greater height and body mass index (BMI) have been associated with an increased risk of thyroid cancer, particularly papillary carcinoma, the most common and least aggressive subtype. Few studies have evaluated these associations in relation to other, more aggressive histologic types or thyroid cancer-specific mortality.</div>
</front>
</TEI>
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Anthropometric Factors and Thyroid Cancer Risk by Histological Subtype: Pooled Analysis of 22 Prospective Studies

Anthropometric Factors and Thyroid Cancer Risk by Histological Subtype: Pooled Analysis of 22 Prospective Studies

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