One million haemopoietic stem-cell transplants: a retrospective observational study.
Identifieur interne : 002E95 ( Ncbi/Merge ); précédent : 002E94; suivant : 002E96One million haemopoietic stem-cell transplants: a retrospective observational study.
Auteurs : Alois Gratwohl [Suisse] ; Marcelo C. Pasquini [États-Unis] ; Mahmoud Aljurf [Arabie saoudite] ; Yoshiko Atsuta [Japon] ; Helen Baldomero [Suisse] ; Lydia Foeken [Pays-Bas] ; Michael Gratwohl [Suisse] ; Luis Fernando Bouzas [Brésil] ; Dennis Confer [États-Unis] ; Karl Frauendorfer [Suisse] ; Eliane Gluckman [France] ; Hildegard Greinix [Autriche] ; Mary Horowitz [États-Unis] ; Minako Iida [Japon] ; Jeff Lipton [Canada] ; Alejandro Madrigal [Royaume-Uni] ; Mohamad Mohty [France] ; Luc Noel [Suisse] ; Nicolas Novitzky [Afrique du Sud] ; José Nunez [Suisse] ; Machteld Oudshoorn [Pays-Bas] ; Jakob Passweg [Suisse] ; Jon Van Rood [Pays-Bas] ; Jeff Szer [Australie] ; Karl Blume [États-Unis] ; Frederic R. Appelbaum [États-Unis] ; Yoshihisa Kodera [Japon] ; Dietger Niederwieser [Allemagne]Source :
- The Lancet. Haematology [ 2352-3026 ] ; 2015.
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Abstract
The transplantation of cells, tissues, and organs has been recognised by WHO as an important medical task for its member states; however, information about how to best organise transplantation is scarce. We aimed to document the activity worldwide from the beginning of transplantation and search for region adapted indications and associations between transplant rates and macroeconomics.
DOI: 10.1016/S2352-3026(15)00028-9
PubMed: 26687803
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pubmed:26687803Le document en format XML
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<author><name sortKey="Aljurf, Mahmoud" sort="Aljurf, Mahmoud" uniqKey="Aljurf M" first="Mahmoud" last="Aljurf">Mahmoud Aljurf</name>
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<author><name sortKey="Atsuta, Yoshiko" sort="Atsuta, Yoshiko" uniqKey="Atsuta Y" first="Yoshiko" last="Atsuta">Yoshiko Atsuta</name>
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<author><name sortKey="Baldomero, Helen" sort="Baldomero, Helen" uniqKey="Baldomero H" first="Helen" last="Baldomero">Helen Baldomero</name>
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<author><name sortKey="Foeken, Lydia" sort="Foeken, Lydia" uniqKey="Foeken L" first="Lydia" last="Foeken">Lydia Foeken</name>
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<author><name sortKey="Bouzas, Luis Fernando" sort="Bouzas, Luis Fernando" uniqKey="Bouzas L" first="Luis Fernando" last="Bouzas">Luis Fernando Bouzas</name>
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<author><name sortKey="Confer, Dennis" sort="Confer, Dennis" uniqKey="Confer D" first="Dennis" last="Confer">Dennis Confer</name>
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<author><name sortKey="Frauendorfer, Karl" sort="Frauendorfer, Karl" uniqKey="Frauendorfer K" first="Karl" last="Frauendorfer">Karl Frauendorfer</name>
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<author><name sortKey="Gluckman, Eliane" sort="Gluckman, Eliane" uniqKey="Gluckman E" first="Eliane" last="Gluckman">Eliane Gluckman</name>
<affiliation wicri:level="3"><nlm:affiliation>Eurocord Foundation, Paris, France.</nlm:affiliation>
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<author><name sortKey="Greinix, Hildegard" sort="Greinix, Hildegard" uniqKey="Greinix H" first="Hildegard" last="Greinix">Hildegard Greinix</name>
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<author><name sortKey="Horowitz, Mary" sort="Horowitz, Mary" uniqKey="Horowitz M" first="Mary" last="Horowitz">Mary Horowitz</name>
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<author><name sortKey="Iida, Minako" sort="Iida, Minako" uniqKey="Iida M" first="Minako" last="Iida">Minako Iida</name>
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</affiliation>
</author>
<author><name sortKey="Lipton, Jeff" sort="Lipton, Jeff" uniqKey="Lipton J" first="Jeff" last="Lipton">Jeff Lipton</name>
<affiliation wicri:level="1"><nlm:affiliation>The Canadian Blood and Marrow Transplantation Group (CBMTG), Princess Margaret Hospital, Toronto, Canada.</nlm:affiliation>
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</affiliation>
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<author><name sortKey="Madrigal, Alejandro" sort="Madrigal, Alejandro" uniqKey="Madrigal A" first="Alejandro" last="Madrigal">Alejandro Madrigal</name>
<affiliation wicri:level="4"><nlm:affiliation>Anthony Nolan Research Institute, Royal Free and University College London, UK.</nlm:affiliation>
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</placeName>
<orgName type="university">University College de Londres</orgName>
</affiliation>
</author>
<author><name sortKey="Mohty, Mohamad" sort="Mohty, Mohamad" uniqKey="Mohty M" first="Mohamad" last="Mohty">Mohamad Mohty</name>
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<author><name sortKey="Noel, Luc" sort="Noel, Luc" uniqKey="Noel L" first="Luc" last="Noel">Luc Noel</name>
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<author><name sortKey="Novitzky, Nicolas" sort="Novitzky, Nicolas" uniqKey="Novitzky N" first="Nicolas" last="Novitzky">Nicolas Novitzky</name>
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</author>
<author><name sortKey="Nunez, Jose" sort="Nunez, Jose" uniqKey="Nunez J" first="José" last="Nunez">José Nunez</name>
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<author><name sortKey="Oudshoorn, Machteld" sort="Oudshoorn, Machteld" uniqKey="Oudshoorn M" first="Machteld" last="Oudshoorn">Machteld Oudshoorn</name>
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</placeName>
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<author><name sortKey="Passweg, Jakob" sort="Passweg, Jakob" uniqKey="Passweg J" first="Jakob" last="Passweg">Jakob Passweg</name>
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<wicri:noRegion>Basel</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Van Rood, Jon" sort="Van Rood, Jon" uniqKey="Van Rood J" first="Jon" last="Van Rood">Jon Van Rood</name>
<affiliation wicri:level="3"><nlm:affiliation>Bone Marrow Donors Worldwide, Leiden, Netherlands.</nlm:affiliation>
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<placeName><settlement type="city">Leyde</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
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</author>
<author><name sortKey="Szer, Jeff" sort="Szer, Jeff" uniqKey="Szer J" first="Jeff" last="Szer">Jeff Szer</name>
<affiliation wicri:level="1"><nlm:affiliation>The Australasian Bone Marrow Transplant Recipient Registry (ABMTRR), Royal Melbourne Hospital, Parkville, Victoria, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>The Australasian Bone Marrow Transplant Recipient Registry (ABMTRR), Royal Melbourne Hospital, Parkville, Victoria</wicri:regionArea>
<wicri:noRegion>Victoria</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Blume, Karl" sort="Blume, Karl" uniqKey="Blume K" first="Karl" last="Blume">Karl Blume</name>
<affiliation wicri:level="1"><nlm:affiliation>Stanford University School of Medicine, Standford, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Stanford University School of Medicine, Standford</wicri:regionArea>
<wicri:noRegion>Standford</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Appelbaum, Frederic R" sort="Appelbaum, Frederic R" uniqKey="Appelbaum F" first="Frederic R" last="Appelbaum">Frederic R. Appelbaum</name>
<affiliation wicri:level="1"><nlm:affiliation>Fred Hutchinson Cancer Research Center, Seattle, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Fred Hutchinson Cancer Research Center, Seattle</wicri:regionArea>
<wicri:noRegion>Seattle</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kodera, Yoshihisa" sort="Kodera, Yoshihisa" uniqKey="Kodera Y" first="Yoshihisa" last="Kodera">Yoshihisa Kodera</name>
<affiliation wicri:level="1"><nlm:affiliation>Aichi Medical University, School of Medicine, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Aichi Medical University, School of Medicine</wicri:regionArea>
<wicri:noRegion>School of Medicine</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Niederwieser, Dietger" sort="Niederwieser, Dietger" uniqKey="Niederwieser D" first="Dietger" last="Niederwieser">Dietger Niederwieser</name>
<affiliation wicri:level="3"><nlm:affiliation>Hematology-Oncology Department, University Hospital, Leipzig, Germany. Electronic address: dietger.niederwieser@medizin.uni-leipzig.de.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Hematology-Oncology Department, University Hospital, Leipzig</wicri:regionArea>
<placeName><region type="land" nuts="1">Saxe (Land)</region>
<region type="district" nuts="2">District de Leipzig</region>
<settlement type="city">Leipzig</settlement>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">One million haemopoietic stem-cell transplants: a retrospective observational study.</title>
<author><name sortKey="Gratwohl, Alois" sort="Gratwohl, Alois" uniqKey="Gratwohl A" first="Alois" last="Gratwohl">Alois Gratwohl</name>
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<author><name sortKey="Pasquini, Marcelo C" sort="Pasquini, Marcelo C" uniqKey="Pasquini M" first="Marcelo C" last="Pasquini">Marcelo C. Pasquini</name>
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<author><name sortKey="Aljurf, Mahmoud" sort="Aljurf, Mahmoud" uniqKey="Aljurf M" first="Mahmoud" last="Aljurf">Mahmoud Aljurf</name>
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<country xml:lang="fr">Arabie saoudite</country>
<wicri:regionArea>The Eastern Mediterranean Blood and Marrow Transplantation Group (EMBMT), King Faisal Specialist Hospital & Research Centre, Riyadh</wicri:regionArea>
<wicri:noRegion>Riyadh</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Atsuta, Yoshiko" sort="Atsuta, Yoshiko" uniqKey="Atsuta Y" first="Yoshiko" last="Atsuta">Yoshiko Atsuta</name>
<affiliation wicri:level="1"><nlm:affiliation>Japanese Data Center for Hematopoietic Cell Transplantation, Nagoya, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Japanese Data Center for Hematopoietic Cell Transplantation, Nagoya</wicri:regionArea>
<wicri:noRegion>Nagoya</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Baldomero, Helen" sort="Baldomero, Helen" uniqKey="Baldomero H" first="Helen" last="Baldomero">Helen Baldomero</name>
<affiliation wicri:level="1"><nlm:affiliation>Worldwide Network for Blood and Marrow Transplantation (WBMT) Transplant Activity Survey Office, University Hospital, Basel, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Worldwide Network for Blood and Marrow Transplantation (WBMT) Transplant Activity Survey Office, University Hospital, Basel</wicri:regionArea>
<wicri:noRegion>Basel</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Foeken, Lydia" sort="Foeken, Lydia" uniqKey="Foeken L" first="Lydia" last="Foeken">Lydia Foeken</name>
<affiliation wicri:level="3"><nlm:affiliation>World Marrow Donor Association, Europdonor Foundation, Leiden, Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>World Marrow Donor Association, Europdonor Foundation, Leiden</wicri:regionArea>
<placeName><settlement type="city">Leyde</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
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<author><name sortKey="Gratwohl, Michael" sort="Gratwohl, Michael" uniqKey="Gratwohl M" first="Michael" last="Gratwohl">Michael Gratwohl</name>
<affiliation wicri:level="1"><nlm:affiliation>Institute for Operations Research and Computational Finances, University of St Gallen, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Institute for Operations Research and Computational Finances, University of St Gallen</wicri:regionArea>
<wicri:noRegion>University of St Gallen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Bouzas, Luis Fernando" sort="Bouzas, Luis Fernando" uniqKey="Bouzas L" first="Luis Fernando" last="Bouzas">Luis Fernando Bouzas</name>
<affiliation wicri:level="3"><nlm:affiliation>The Latin American Blood and Marrow Transplantation Group (LABMT), Instituto Nacional de Cancer, Rio de Janeiro, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>The Latin American Blood and Marrow Transplantation Group (LABMT), Instituto Nacional de Cancer, Rio de Janeiro</wicri:regionArea>
<placeName><settlement type="city">Rio de Janeiro</settlement>
<region type="state">État de Rio de Janeiro</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Confer, Dennis" sort="Confer, Dennis" uniqKey="Confer D" first="Dennis" last="Confer">Dennis Confer</name>
<affiliation wicri:level="1"><nlm:affiliation>National Marrow Donor Program, Minneapolis, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>National Marrow Donor Program, Minneapolis</wicri:regionArea>
<wicri:noRegion>Minneapolis</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Frauendorfer, Karl" sort="Frauendorfer, Karl" uniqKey="Frauendorfer K" first="Karl" last="Frauendorfer">Karl Frauendorfer</name>
<affiliation wicri:level="1"><nlm:affiliation>Institute for Operations Research and Computational Finances, University of St Gallen, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Institute for Operations Research and Computational Finances, University of St Gallen</wicri:regionArea>
<wicri:noRegion>University of St Gallen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gluckman, Eliane" sort="Gluckman, Eliane" uniqKey="Gluckman E" first="Eliane" last="Gluckman">Eliane Gluckman</name>
<affiliation wicri:level="3"><nlm:affiliation>Eurocord Foundation, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Eurocord Foundation, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Greinix, Hildegard" sort="Greinix, Hildegard" uniqKey="Greinix H" first="Hildegard" last="Greinix">Hildegard Greinix</name>
<affiliation wicri:level="3"><nlm:affiliation>Medical Clinic, University of Vienna, Vienna, Austria.</nlm:affiliation>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Medical Clinic, University of Vienna, Vienna</wicri:regionArea>
<placeName><settlement type="city">Vienne (Autriche)</settlement>
<region nuts="2" type="province">Vienne (Autriche)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Horowitz, Mary" sort="Horowitz, Mary" uniqKey="Horowitz M" first="Mary" last="Horowitz">Mary Horowitz</name>
<affiliation wicri:level="1"><nlm:affiliation>The Center for International Blood and Marrow Transplant Research (CIBMTR), Medical College of Wisconsin, Milwaukee, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>The Center for International Blood and Marrow Transplant Research (CIBMTR), Medical College of Wisconsin, Milwaukee</wicri:regionArea>
<wicri:noRegion>Milwaukee</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Iida, Minako" sort="Iida, Minako" uniqKey="Iida M" first="Minako" last="Iida">Minako Iida</name>
<affiliation wicri:level="1"><nlm:affiliation>The Asian Pacific Blood and Marrow Transplantation Group (APBMT) Data Centre, Aichi Medical University, School of Medicine, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>The Asian Pacific Blood and Marrow Transplantation Group (APBMT) Data Centre, Aichi Medical University, School of Medicine</wicri:regionArea>
<wicri:noRegion>School of Medicine</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lipton, Jeff" sort="Lipton, Jeff" uniqKey="Lipton J" first="Jeff" last="Lipton">Jeff Lipton</name>
<affiliation wicri:level="1"><nlm:affiliation>The Canadian Blood and Marrow Transplantation Group (CBMTG), Princess Margaret Hospital, Toronto, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>The Canadian Blood and Marrow Transplantation Group (CBMTG), Princess Margaret Hospital, Toronto</wicri:regionArea>
<wicri:noRegion>Toronto</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Madrigal, Alejandro" sort="Madrigal, Alejandro" uniqKey="Madrigal A" first="Alejandro" last="Madrigal">Alejandro Madrigal</name>
<affiliation wicri:level="4"><nlm:affiliation>Anthony Nolan Research Institute, Royal Free and University College London, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Anthony Nolan Research Institute, Royal Free and University College London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
<orgName type="university">University College de Londres</orgName>
</affiliation>
</author>
<author><name sortKey="Mohty, Mohamad" sort="Mohty, Mohamad" uniqKey="Mohty M" first="Mohamad" last="Mohty">Mohamad Mohty</name>
<affiliation wicri:level="3"><nlm:affiliation>The European Society for Blood and Marrow Transplantation (EBMT), Hôpital St. Antoine, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>The European Society for Blood and Marrow Transplantation (EBMT), Hôpital St. Antoine, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Noel, Luc" sort="Noel, Luc" uniqKey="Noel L" first="Luc" last="Noel">Luc Noel</name>
<affiliation wicri:level="1"><nlm:affiliation>WHO, Geneva, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>WHO, Geneva</wicri:regionArea>
<wicri:noRegion>Geneva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Novitzky, Nicolas" sort="Novitzky, Nicolas" uniqKey="Novitzky N" first="Nicolas" last="Novitzky">Nicolas Novitzky</name>
<affiliation wicri:level="1"><nlm:affiliation>The African Blood and Marrow Transplantation Group (AFBMT), Johannesburg, South Africa.</nlm:affiliation>
<country xml:lang="fr">Afrique du Sud</country>
<wicri:regionArea>The African Blood and Marrow Transplantation Group (AFBMT), Johannesburg</wicri:regionArea>
<wicri:noRegion>Johannesburg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Nunez, Jose" sort="Nunez, Jose" uniqKey="Nunez J" first="José" last="Nunez">José Nunez</name>
<affiliation wicri:level="1"><nlm:affiliation>WHO, Geneva, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>WHO, Geneva</wicri:regionArea>
<wicri:noRegion>Geneva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Oudshoorn, Machteld" sort="Oudshoorn, Machteld" uniqKey="Oudshoorn M" first="Machteld" last="Oudshoorn">Machteld Oudshoorn</name>
<affiliation wicri:level="3"><nlm:affiliation>World Marrow Donor Association, Europdonor Foundation, Leiden, Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>World Marrow Donor Association, Europdonor Foundation, Leiden</wicri:regionArea>
<placeName><settlement type="city">Leyde</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Passweg, Jakob" sort="Passweg, Jakob" uniqKey="Passweg J" first="Jakob" last="Passweg">Jakob Passweg</name>
<affiliation wicri:level="1"><nlm:affiliation>Worldwide Network for Blood and Marrow Transplantation (WBMT) Transplant Activity Survey Office, University Hospital, Basel, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Worldwide Network for Blood and Marrow Transplantation (WBMT) Transplant Activity Survey Office, University Hospital, Basel</wicri:regionArea>
<wicri:noRegion>Basel</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Van Rood, Jon" sort="Van Rood, Jon" uniqKey="Van Rood J" first="Jon" last="Van Rood">Jon Van Rood</name>
<affiliation wicri:level="3"><nlm:affiliation>Bone Marrow Donors Worldwide, Leiden, Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Bone Marrow Donors Worldwide, Leiden</wicri:regionArea>
<placeName><settlement type="city">Leyde</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Szer, Jeff" sort="Szer, Jeff" uniqKey="Szer J" first="Jeff" last="Szer">Jeff Szer</name>
<affiliation wicri:level="1"><nlm:affiliation>The Australasian Bone Marrow Transplant Recipient Registry (ABMTRR), Royal Melbourne Hospital, Parkville, Victoria, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>The Australasian Bone Marrow Transplant Recipient Registry (ABMTRR), Royal Melbourne Hospital, Parkville, Victoria</wicri:regionArea>
<wicri:noRegion>Victoria</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Blume, Karl" sort="Blume, Karl" uniqKey="Blume K" first="Karl" last="Blume">Karl Blume</name>
<affiliation wicri:level="1"><nlm:affiliation>Stanford University School of Medicine, Standford, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Stanford University School of Medicine, Standford</wicri:regionArea>
<wicri:noRegion>Standford</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Appelbaum, Frederic R" sort="Appelbaum, Frederic R" uniqKey="Appelbaum F" first="Frederic R" last="Appelbaum">Frederic R. Appelbaum</name>
<affiliation wicri:level="1"><nlm:affiliation>Fred Hutchinson Cancer Research Center, Seattle, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Fred Hutchinson Cancer Research Center, Seattle</wicri:regionArea>
<wicri:noRegion>Seattle</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kodera, Yoshihisa" sort="Kodera, Yoshihisa" uniqKey="Kodera Y" first="Yoshihisa" last="Kodera">Yoshihisa Kodera</name>
<affiliation wicri:level="1"><nlm:affiliation>Aichi Medical University, School of Medicine, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Aichi Medical University, School of Medicine</wicri:regionArea>
<wicri:noRegion>School of Medicine</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Niederwieser, Dietger" sort="Niederwieser, Dietger" uniqKey="Niederwieser D" first="Dietger" last="Niederwieser">Dietger Niederwieser</name>
<affiliation wicri:level="3"><nlm:affiliation>Hematology-Oncology Department, University Hospital, Leipzig, Germany. Electronic address: dietger.niederwieser@medizin.uni-leipzig.de.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Hematology-Oncology Department, University Hospital, Leipzig</wicri:regionArea>
<placeName><region type="land" nuts="1">Saxe (Land)</region>
<region type="district" nuts="2">District de Leipzig</region>
<settlement type="city">Leipzig</settlement>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">The Lancet. Haematology</title>
<idno type="eISSN">2352-3026</idno>
<imprint><date when="2015" type="published">2015</date>
</imprint>
</series>
</biblStruct>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Data Collection</term>
<term>Global Health</term>
<term>Hematopoietic Stem Cell Transplantation</term>
<term>Humans</term>
<term>Registries</term>
<term>Retrospective Studies</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Collecte de données</term>
<term>Enregistrements</term>
<term>Humains</term>
<term>Santé mondiale</term>
<term>Transplantation de cellules souches hématopoïétiques</term>
<term>Études rétrospectives</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Data Collection</term>
<term>Global Health</term>
<term>Hematopoietic Stem Cell Transplantation</term>
<term>Humans</term>
<term>Registries</term>
<term>Retrospective Studies</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Collecte de données</term>
<term>Enregistrements</term>
<term>Humains</term>
<term>Santé mondiale</term>
<term>Transplantation de cellules souches hématopoïétiques</term>
<term>Études rétrospectives</term>
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<front><div type="abstract" xml:lang="en">The transplantation of cells, tissues, and organs has been recognised by WHO as an important medical task for its member states; however, information about how to best organise transplantation is scarce. We aimed to document the activity worldwide from the beginning of transplantation and search for region adapted indications and associations between transplant rates and macroeconomics.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26687803</PMID>
<DateCreated><Year>2015</Year>
<Month>12</Month>
<Day>21</Day>
</DateCreated>
<DateCompleted><Year>2017</Year>
<Month>10</Month>
<Day>11</Day>
</DateCompleted>
<DateRevised><Year>2017</Year>
<Month>10</Month>
<Day>11</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">2352-3026</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>2</Volume>
<Issue>3</Issue>
<PubDate><Year>2015</Year>
<Month>Mar</Month>
</PubDate>
</JournalIssue>
<Title>The Lancet. Haematology</Title>
<ISOAbbreviation>Lancet Haematol</ISOAbbreviation>
</Journal>
<ArticleTitle>One million haemopoietic stem-cell transplants: a retrospective observational study.</ArticleTitle>
<Pagination><MedlinePgn>e91-100</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1016/S2352-3026(15)00028-9</ELocationID>
<ELocationID EIdType="pii" ValidYN="Y">S2352-3026(15)00028-9</ELocationID>
<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">The transplantation of cells, tissues, and organs has been recognised by WHO as an important medical task for its member states; however, information about how to best organise transplantation is scarce. We aimed to document the activity worldwide from the beginning of transplantation and search for region adapted indications and associations between transplant rates and macroeconomics.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Between Jan 1, 2006, and Dec 31, 2014, the Worldwide Network for Blood and Marrow Transplantation collected data for the evolution of haemopoietic stem-cell transplantation (HSCT) activity and volunteer donors in the 194 WHO member states.</AbstractText>
<AbstractText Label="FINDINGS" NlmCategory="RESULTS">953,651 HSCTs (553,350 [58%] autologous and 400,301 [42%] allogeneic) were reported by 1516 transplant centres from 75 countries. No transplants were done in countries with fewer than 300,000 inhabitants, a surface area less than 700 km(2), and a gross national income per person of US$1260 or lower. Use of HSCT increased from the first transplant in 1957 to almost 10,000 by 1985. We recorded a cumulative total of about 100,000 transplants by 1995, and an estimated 1 million by December, 2012. Unrelated donor registries contributed 22·3 million typed volunteer donors and 645,646 cord blood products by 2012. Numbers of allogeneic HSCTs increased in the past 35 years with no signs of saturation (R(2)=0·989). Transplant rates were higher in countries with more resources, more transplant teams, and an unrelated donor infrastructure.</AbstractText>
<AbstractText Label="INTERPRETATION" NlmCategory="CONCLUSIONS">Our findings show achievements and high unmet needs and give guidance for decisions; to grant access for patients, to provide a donor infrastructure, and to limit overuse by defining risk and region adapted indications for HSCT as an efficient and cost-effective approach for life-threatening, potentially curable diseases.</AbstractText>
<AbstractText Label="FUNDING" NlmCategory="BACKGROUND">Funding for this study was indirectly provided by support of the WBMT.</AbstractText>
<CopyrightInformation>Copyright © 2015 Elsevier Ltd. All rights reserved.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Gratwohl</LastName>
<ForeName>Alois</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Worldwide Network for Blood and Marrow Transplantation (WBMT) Transplant Activity Survey Office, University Hospital, Basel, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Pasquini</LastName>
<ForeName>Marcelo C</ForeName>
<Initials>MC</Initials>
<AffiliationInfo><Affiliation>The Center for International Blood and Marrow Transplant Research (CIBMTR), Medical College of Wisconsin, Milwaukee, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Aljurf</LastName>
<ForeName>Mahmoud</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>The Eastern Mediterranean Blood and Marrow Transplantation Group (EMBMT), King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Atsuta</LastName>
<ForeName>Yoshiko</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>Japanese Data Center for Hematopoietic Cell Transplantation, Nagoya, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Baldomero</LastName>
<ForeName>Helen</ForeName>
<Initials>H</Initials>
<AffiliationInfo><Affiliation>Worldwide Network for Blood and Marrow Transplantation (WBMT) Transplant Activity Survey Office, University Hospital, Basel, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Foeken</LastName>
<ForeName>Lydia</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>World Marrow Donor Association, Europdonor Foundation, Leiden, Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gratwohl</LastName>
<ForeName>Michael</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Institute for Operations Research and Computational Finances, University of St Gallen, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bouzas</LastName>
<ForeName>Luis Fernando</ForeName>
<Initials>LF</Initials>
<AffiliationInfo><Affiliation>The Latin American Blood and Marrow Transplantation Group (LABMT), Instituto Nacional de Cancer, Rio de Janeiro, Brazil.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Confer</LastName>
<ForeName>Dennis</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>National Marrow Donor Program, Minneapolis, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Frauendorfer</LastName>
<ForeName>Karl</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>Institute for Operations Research and Computational Finances, University of St Gallen, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gluckman</LastName>
<ForeName>Eliane</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Eurocord Foundation, Paris, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Greinix</LastName>
<ForeName>Hildegard</ForeName>
<Initials>H</Initials>
<AffiliationInfo><Affiliation>Medical Clinic, University of Vienna, Vienna, Austria.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Horowitz</LastName>
<ForeName>Mary</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>The Center for International Blood and Marrow Transplant Research (CIBMTR), Medical College of Wisconsin, Milwaukee, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Iida</LastName>
<ForeName>Minako</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>The Asian Pacific Blood and Marrow Transplantation Group (APBMT) Data Centre, Aichi Medical University, School of Medicine, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Lipton</LastName>
<ForeName>Jeff</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>The Canadian Blood and Marrow Transplantation Group (CBMTG), Princess Margaret Hospital, Toronto, Canada.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Madrigal</LastName>
<ForeName>Alejandro</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Anthony Nolan Research Institute, Royal Free and University College London, UK.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Mohty</LastName>
<ForeName>Mohamad</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>The European Society for Blood and Marrow Transplantation (EBMT), Hôpital St. Antoine, Paris, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Noel</LastName>
<ForeName>Luc</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>WHO, Geneva, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Novitzky</LastName>
<ForeName>Nicolas</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>The African Blood and Marrow Transplantation Group (AFBMT), Johannesburg, South Africa.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Nunez</LastName>
<ForeName>José</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>WHO, Geneva, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Oudshoorn</LastName>
<ForeName>Machteld</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>World Marrow Donor Association, Europdonor Foundation, Leiden, Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Passweg</LastName>
<ForeName>Jakob</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Worldwide Network for Blood and Marrow Transplantation (WBMT) Transplant Activity Survey Office, University Hospital, Basel, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>van Rood</LastName>
<ForeName>Jon</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Bone Marrow Donors Worldwide, Leiden, Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Szer</LastName>
<ForeName>Jeff</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>The Australasian Bone Marrow Transplant Recipient Registry (ABMTRR), Royal Melbourne Hospital, Parkville, Victoria, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Blume</LastName>
<ForeName>Karl</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>Stanford University School of Medicine, Standford, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Appelbaum</LastName>
<ForeName>Frederic R</ForeName>
<Initials>FR</Initials>
<AffiliationInfo><Affiliation>Fred Hutchinson Cancer Research Center, Seattle, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kodera</LastName>
<ForeName>Yoshihisa</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>Aichi Medical University, School of Medicine, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Niederwieser</LastName>
<ForeName>Dietger</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>Hematology-Oncology Department, University Hospital, Leipzig, Germany. Electronic address: dietger.niederwieser@medizin.uni-leipzig.de.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><CollectiveName>Worldwide Network for Blood and Marrow Transplantation (WBMT)</CollectiveName>
</Author>
</AuthorList>
<Language>eng</Language>
<GrantList CompleteYN="Y"><Grant><GrantID>001</GrantID>
<Agency>World Health Organization</Agency>
<Country>International</Country>
</Grant>
</GrantList>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D064888">Observational Study</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2015</Year>
<Month>02</Month>
<Day>27</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>England</Country>
<MedlineTA>Lancet Haematol</MedlineTA>
<NlmUniqueID>101643584</NlmUniqueID>
<ISSNLinking>2352-3026</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<CommentsCorrectionsList><CommentsCorrections RefType="CommentIn"><RefSource>Lancet Haematol. 2015 Mar;2(3):e83-4</RefSource>
<PMID Version="1">26687799</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="ErratumIn"><RefSource>Lancet Haematol. 2015 May;2(5):e184</RefSource>
</CommentsCorrections>
</CommentsCorrectionsList>
<MeshHeadingList><MeshHeading><DescriptorName UI="D003625" MajorTopicYN="N">Data Collection</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014943" MajorTopicYN="N">Global Health</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018380" MajorTopicYN="Y">Hematopoietic Stem Cell Transplantation</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012042" MajorTopicYN="Y">Registries</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2014</Year>
<Month>12</Month>
<Day>21</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="revised"><Year>2015</Year>
<Month>01</Month>
<Day>27</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2015</Year>
<Month>01</Month>
<Day>30</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2015</Year>
<Month>12</Month>
<Day>22</Day>
<Hour>6</Hour>
<Minute>0</Minute>
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<PubMedPubDate PubStatus="pubmed"><Year>2015</Year>
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<li>Brésil</li>
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<li>District de Leipzig</li>
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<li>Vienne (Autriche)</li>
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