Young Women With Abdominal Obesity Have Subclinical Myocardial Dysfunction.
Identifieur interne : 002611 ( Ncbi/Merge ); précédent : 002610; suivant : 002612Young Women With Abdominal Obesity Have Subclinical Myocardial Dysfunction.
Auteurs : Bianca L. Share [Australie] ; André La Gerche [Australie] ; Geraldine A. Naughton [Australie] ; Philippe Obert [France] ; Justin G. Kemp [Australie]Source :
- The Canadian journal of cardiology [ 1916-7075 ] ; 2015.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Cardiopathies (physiopathologie), Cardiopathies (épidémiologie), Coeur (physiopathologie), Facteurs de risque, Femelle, Humains, Imagerie d'élasticité tissulaire, Jeune adulte, Obésité abdominale (imagerie diagnostique), Obésité abdominale (physiopathologie), Obésité abdominale (épidémiologie), Échocardiographie-doppler.
- MESH :
- imagerie diagnostique : Obésité abdominale.
- physiopathologie : Cardiopathies, Coeur, Obésité abdominale.
- épidémiologie : Cardiopathies, Obésité abdominale.
- Adolescent, Adulte, Facteurs de risque, Femelle, Humains, Imagerie d'élasticité tissulaire, Jeune adulte, Échocardiographie-doppler.
English descriptors
- KwdEn :
- Adolescent, Adult, Echocardiography, Doppler, Elasticity Imaging Techniques, Female, Heart (physiopathology), Heart Diseases (epidemiology), Heart Diseases (physiopathology), Humans, Obesity, Abdominal (diagnostic imaging), Obesity, Abdominal (epidemiology), Obesity, Abdominal (physiopathology), Risk Factors, Young Adult.
- MESH :
- diagnostic imaging : Obesity, Abdominal.
- epidemiology : Heart Diseases, Obesity, Abdominal.
- physiopathology : Heart, Heart Diseases, Obesity, Abdominal.
- Adolescent, Adult, Echocardiography, Doppler, Elasticity Imaging Techniques, Female, Humans, Risk Factors, Young Adult.
Abstract
Abdominal obesity is an independent risk factor for cardiovascular disease. The effect of abdominal obesity on myocardial function in young obese women remains unknown. Therefore, we aimed to investigate cardiac morphology and function, myocardial deformation, and mechanical indices, in young women with and without abdominal obesity.
DOI: 10.1016/j.cjca.2015.02.004
PubMed: 26002065
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pubmed:26002065Le document en format XML
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<term>Female</term>
<term>Heart (physiopathology)</term>
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<term>Imagerie d'élasticité tissulaire</term>
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<front><div type="abstract" xml:lang="en">Abdominal obesity is an independent risk factor for cardiovascular disease. The effect of abdominal obesity on myocardial function in young obese women remains unknown. Therefore, we aimed to investigate cardiac morphology and function, myocardial deformation, and mechanical indices, in young women with and without abdominal obesity.</div>
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<ArticleTitle>Young Women With Abdominal Obesity Have Subclinical Myocardial Dysfunction.</ArticleTitle>
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<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Abdominal obesity is an independent risk factor for cardiovascular disease. The effect of abdominal obesity on myocardial function in young obese women remains unknown. Therefore, we aimed to investigate cardiac morphology and function, myocardial deformation, and mechanical indices, in young women with and without abdominal obesity.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Cross-sectional analyses of 39 women with abdominal obesity (waist circumference ≥ 80 cm) and 33 nonobese control subjects (waist circumference < 80 cm) aged 18-30 years underwent conventional echocardiographic measures of cardiac morphology and function together with tissue Doppler, and 2-dimensional speckle tracking measures of myocardial deformation and mechanics. Cardiometabolic risk factors including anthropometric, hypertension, biochemistry, and fitness were also assessed.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Standard echocardiography results for cardiac morphology and function were similar between groups, with the exception of larger left atrial dimensions in women with abdominal obesity (P ≤ 0.05). Compared with control subjects, women with abdominal obesity also demonstrated reduced systolic and diastolic mitral annular plane velocities, increased left atrial pressure surrogates (E/diastolic mitral annular plane velocity), and prolonged timing measures of diastolic function including isovolumic relaxation time and transmitral deceleration time (P ≤ 0.05). In addition, longitudinal strain and diastolic strain rate were reduced in women with abdominal obesity (P ≤ 0.05) but circumferential deformation and myocardial mechanics (twist indices and rotation) were preserved. Markers of abdominal obesity retained an independent direct correlation with parameters of cardiac dysfunction, explaining 12%-39% of the overall variability.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">A young, otherwise healthy group of women with abdominal obesity displayed subclinical cardiac dysfunction indicated using selected tissue Doppler imaging and speckle tracking echocardiography measures.</AbstractText>
<CopyrightInformation>Copyright © 2015 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.</CopyrightInformation>
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<ForeName>Bianca L</ForeName>
<Initials>BL</Initials>
<AffiliationInfo><Affiliation>School of Exercise Science, Australian Catholic University, Melbourne, Australia. Electronic address: bianca.share@acu.edu.au.</Affiliation>
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<Author ValidYN="Y"><LastName>La Gerche</LastName>
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