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Influence of light exposure during early life on the age of onset of bipolar disorder.

Identifieur interne : 002441 ( Ncbi/Merge ); précédent : 002440; suivant : 002442

Influence of light exposure during early life on the age of onset of bipolar disorder.

Auteurs : Michael Bauer [Allemagne] ; Tasha Glenn [États-Unis] ; Martin Alda [Canada] ; Ole A. Andreassen [Norvège] ; Elias Angelopoulos [Grèce] ; Raffaella Ardau [Italie] ; Christopher Baethge [Allemagne] ; Rita Bauer [Allemagne] ; Bernhard T. Baune [Australie] ; Frank Bellivier [France] ; Robert H. Belmaker [Israël] ; Michael Berk [Australie] ; Thomas D. Bjella [Norvège] ; Letizia Bossini [Italie] ; Yuly Bersudsky [Israël] ; Eric Yat Wo Cheung [Hong Kong] ; Jörn Conell [Allemagne] ; Maria Del Zompo [Italie] ; Seetal Dodd [Australie] ; Bruno Etain [France] ; Andrea Fagiolini [Italie] ; Mark A. Frye [États-Unis] ; Kostas N. Fountoulakis [Grèce] ; Jade Garneau-Fournier [États-Unis] ; Ana Gonzalez-Pinto [Espagne] ; John F. Gottlieb [États-Unis] ; Hirohiko Harima [Japon] ; Stefanie Hassel [Canada] ; Chantal Henry [France] ; Apostolos Iacovides [Grèce] ; Erkki T. Isomets [Finlande] ; Flávio Kapczinski [Brésil] ; Sebastian Kliwicki [Pologne] ; Barbara König [Autriche] ; Rikke Krogh [Danemark] ; Mauricio Kunz [Brésil] ; Beny Lafer [Brésil] ; Erik R. Larsen [Danemark] ; Ute Lewitzka [Allemagne] ; Carlos Lopez-Jaramillo [Colombie] ; Glenda Macqueen [Canada] ; Mirko Manchia [Canada] ; Wendy Marsh [États-Unis] ; M Nica Martinez-Cengotitabengoa [Espagne] ; Ingrid Melle [Norvège] ; Scott Monteith [États-Unis] ; Gunnar Morken [Norvège] ; Rodrigo Munoz [États-Unis] ; Fabiano G. Nery [Brésil] ; Claire O'Donovan [Canada] ; Yamima Osher [Israël] ; Andrea Pfennig [Allemagne] ; Danilo Quiroz [Chili] ; Raj Ramesar [Afrique du Sud] ; Natalie Rasgon [États-Unis] ; Andreas Reif [Allemagne] ; Philipp Ritter [Allemagne] ; Janusz K. Rybakowski [Pologne] ; Kemal Sagduyu [États-Unis] ; Ângela Miranda-Scippa [Brésil] ; Emanuel Severus [Allemagne] ; Christian Simhandl [Autriche] ; Dan J. Stein [Afrique du Sud] ; Sergio Strejilevich [Argentine] ; Ahmad Hatim Sulaiman [Malaisie] ; Kirsi Suominen [Finlande] ; Hiromi Tagata [Japon] ; Yoshitaka Tatebayashi [Japon] ; Carla Torrent [Espagne] ; Eduard Vieta [Espagne] ; Biju Viswanath [Inde] ; Mihir J. Wanchoo [États-Unis] ; Mark Zetin [États-Unis] ; Peter C. Whybrow [États-Unis]

Source :

RBID : pubmed:25862378

Descripteurs français

English descriptors

Abstract

Environmental conditions early in life may imprint the circadian system and influence response to environmental signals later in life. We previously determined that a large springtime increase in solar insolation at the onset location was associated with a younger age of onset of bipolar disorder, especially with a family history of mood disorders. This study investigated whether the hours of daylight at the birth location affected this association.

DOI: 10.1016/j.jpsychires.2015.03.013
PubMed: 25862378

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pubmed:25862378

Le document en format XML

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<nlm:affiliation>Psychiatrie, GH Saint-Louis - Lariboisière - F. Widal, AP-HP, INSERM UMR-S1144, Faculté de Médecine, Université D. Diderot, Paris, France; Fondation FondaMental, Créteil, France.</nlm:affiliation>
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<name sortKey="Belmaker, Robert H" sort="Belmaker, Robert H" uniqKey="Belmaker R" first="Robert H" last="Belmaker">Robert H. Belmaker</name>
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<nlm:affiliation>Department of Psychiatry, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva Mental Health Center, Beer Sheva, Israel.</nlm:affiliation>
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<wicri:regionArea>Department of Psychiatry, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva Mental Health Center, Beer Sheva</wicri:regionArea>
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<wicri:regionArea>Department of Molecular Medicine and Department of Mental Health (DAI), University of Siena and University of Siena Medical Center (AOUS), Siena</wicri:regionArea>
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<country xml:lang="fr">Israël</country>
<wicri:regionArea>Department of Psychiatry, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva Mental Health Center, Beer Sheva</wicri:regionArea>
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<name sortKey="Wo Cheung, Eric Yat" sort="Wo Cheung, Eric Yat" uniqKey="Wo Cheung E" first="Eric Yat" last="Wo Cheung">Eric Yat Wo Cheung</name>
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<nlm:affiliation>Department of General Adult Psychiatry, Castle Peak Hospital, Hong Kong.</nlm:affiliation>
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<name sortKey="Dodd, Seetal" sort="Dodd, Seetal" uniqKey="Dodd S" first="Seetal" last="Dodd">Seetal Dodd</name>
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<nlm:affiliation>IMPACT Strategic Research Centre, School of Medicine, Deakin University, Geelong, Victoria 3220, Australia; Department of Psychiatry, University of Melbourne, Parkville, Victoria 3052, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>IMPACT Strategic Research Centre, School of Medicine, Deakin University, Geelong, Victoria 3220, Australia; Department of Psychiatry, University of Melbourne, Parkville, Victoria 3052</wicri:regionArea>
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<name sortKey="Etain, Bruno" sort="Etain, Bruno" uniqKey="Etain B" first="Bruno" last="Etain">Bruno Etain</name>
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<name sortKey="Fagiolini, Andrea" sort="Fagiolini, Andrea" uniqKey="Fagiolini A" first="Andrea" last="Fagiolini">Andrea Fagiolini</name>
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<nlm:affiliation>Department of Molecular Medicine and Department of Mental Health (DAI), University of Siena and University of Siena Medical Center (AOUS), Siena, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Molecular Medicine and Department of Mental Health (DAI), University of Siena and University of Siena Medical Center (AOUS), Siena</wicri:regionArea>
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<name sortKey="Frye, Mark A" sort="Frye, Mark A" uniqKey="Frye M" first="Mark A" last="Frye">Mark A. Frye</name>
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<nlm:affiliation>Department of Psychiatry & Psychology, Mayo Clinic Depression Center, Mayo Clinic, Rochester, MN, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
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<name sortKey="Fountoulakis, Kostas N" sort="Fountoulakis, Kostas N" uniqKey="Fountoulakis K" first="Kostas N" last="Fountoulakis">Kostas N. Fountoulakis</name>
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<nlm:affiliation>3rd Department of Psychiatry, Division of Neurosciences, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.</nlm:affiliation>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>3rd Department of Psychiatry, Division of Neurosciences, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki</wicri:regionArea>
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<author>
<name sortKey="Garneau Fournier, Jade" sort="Garneau Fournier, Jade" uniqKey="Garneau Fournier J" first="Jade" last="Garneau-Fournier">Jade Garneau-Fournier</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Palo Alto, CA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Palo Alto, CA</wicri:regionArea>
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<region type="state">Californie</region>
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<author>
<name sortKey="Gonzalez Pinto, Ana" sort="Gonzalez Pinto, Ana" uniqKey="Gonzalez Pinto A" first="Ana" last="Gonzalez-Pinto">Ana Gonzalez-Pinto</name>
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<nlm:affiliation>Department of Psychiatry, University Hospital of Alava, University of the Basque Country, CIBERSAM, Vitoria, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Department of Psychiatry, University Hospital of Alava, University of the Basque Country, CIBERSAM, Vitoria</wicri:regionArea>
<wicri:noRegion>Vitoria</wicri:noRegion>
</affiliation>
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<name sortKey="Gottlieb, John F" sort="Gottlieb, John F" uniqKey="Gottlieb J" first="John F" last="Gottlieb">John F. Gottlieb</name>
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<nlm:affiliation>Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Feinberg School of Medicine, Northwestern University, Chicago, IL</wicri:regionArea>
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<region type="state">Illinois</region>
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</author>
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<name sortKey="Harima, Hirohiko" sort="Harima, Hirohiko" uniqKey="Harima H" first="Hirohiko" last="Harima">Hirohiko Harima</name>
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<nlm:affiliation>Department of Psychiatry, Tokyo Metropolitan Matsuzawa Hospital, Setagaya, Tokyo, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Psychiatry, Tokyo Metropolitan Matsuzawa Hospital, Setagaya, Tokyo</wicri:regionArea>
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<settlement type="city">Tokyo</settlement>
<region type="région">Région de Kantō</region>
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<name sortKey="Hassel, Stefanie" sort="Hassel, Stefanie" uniqKey="Hassel S" first="Stefanie" last="Hassel">Stefanie Hassel</name>
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<nlm:affiliation>Department of Psychiatry, Faculty of Medicine, University of Calgary, Calgary, AB, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Department of Psychiatry, Faculty of Medicine, University of Calgary, Calgary, AB</wicri:regionArea>
<orgName type="university">Université de Calgary</orgName>
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<settlement type="city">Calgary</settlement>
<region type="state">Alberta</region>
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<author>
<name sortKey="Henry, Chantal" sort="Henry, Chantal" uniqKey="Henry C" first="Chantal" last="Henry">Chantal Henry</name>
<affiliation wicri:level="3">
<nlm:affiliation>AP-HP, Hôpitaux Universitaires Henri-Mondor, INSERM U955 (IMRB), Université Paris Est, Créteil, France; Fondation FondaMental, Créteil, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>AP-HP, Hôpitaux Universitaires Henri-Mondor, INSERM U955 (IMRB), Université Paris Est, Créteil, France; Fondation FondaMental, Créteil</wicri:regionArea>
<placeName>
<region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Créteil</settlement>
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<author>
<name sortKey="Iacovides, Apostolos" sort="Iacovides, Apostolos" uniqKey="Iacovides A" first="Apostolos" last="Iacovides">Apostolos Iacovides</name>
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<nlm:affiliation>3rd Department of Psychiatry, Division of Neurosciences, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.</nlm:affiliation>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>3rd Department of Psychiatry, Division of Neurosciences, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki</wicri:regionArea>
<wicri:noRegion>Thessaloniki</wicri:noRegion>
</affiliation>
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<name sortKey="Isomets, Erkki T" sort="Isomets, Erkki T" uniqKey="Isomets E" first="Erkki T" last="Isomets">Erkki T. Isomets</name>
<affiliation wicri:level="4">
<nlm:affiliation>Department of Psychiatry, Institute of Clinical Medicine, University of Helsinki, Finland; National Institute for Health and Welfare, Helsinki, Finland.</nlm:affiliation>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Psychiatry, Institute of Clinical Medicine, University of Helsinki, Finland; National Institute for Health and Welfare, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName>
<settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
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</author>
<author>
<name sortKey="Kapczinski, Flavio" sort="Kapczinski, Flavio" uniqKey="Kapczinski F" first="Flávio" last="Kapczinski">Flávio Kapczinski</name>
<affiliation wicri:level="4">
<nlm:affiliation>Laboratory of Molecular Psychiatry, Hospital de Clínicas de Porto Alegre, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Laboratory of Molecular Psychiatry, Hospital de Clínicas de Porto Alegre, Federal University of Rio Grande do Sul, Porto Alegre</wicri:regionArea>
<placeName>
<settlement type="city">Porto Alegre</settlement>
<region type="state">Rio Grande do Sul</region>
<settlement type="city">Porto Alegre</settlement>
</placeName>
<orgName type="university">Université fédérale du Rio Grande do Sul</orgName>
</affiliation>
</author>
<author>
<name sortKey="Kliwicki, Sebastian" sort="Kliwicki, Sebastian" uniqKey="Kliwicki S" first="Sebastian" last="Kliwicki">Sebastian Kliwicki</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland.</nlm:affiliation>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea>Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan</wicri:regionArea>
<wicri:noRegion>Poznan</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Konig, Barbara" sort="Konig, Barbara" uniqKey="Konig B" first="Barbara" last="König">Barbara König</name>
<affiliation wicri:level="1">
<nlm:affiliation>BIPOLAR Zentrum Wiener Neustadt, Wiener Neustadt, Austria.</nlm:affiliation>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>BIPOLAR Zentrum Wiener Neustadt, Wiener Neustadt</wicri:regionArea>
<wicri:noRegion>Wiener Neustadt</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Krogh, Rikke" sort="Krogh, Rikke" uniqKey="Krogh R" first="Rikke" last="Krogh">Rikke Krogh</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Affective Disorders, Q, Mood Disorders Research Unit, Aarhus University Hospital, Denmark.</nlm:affiliation>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Department of Affective Disorders, Q, Mood Disorders Research Unit, Aarhus University Hospital</wicri:regionArea>
<wicri:noRegion>Aarhus University Hospital</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Kunz, Mauricio" sort="Kunz, Mauricio" uniqKey="Kunz M" first="Mauricio" last="Kunz">Mauricio Kunz</name>
<affiliation wicri:level="4">
<nlm:affiliation>Laboratory of Molecular Psychiatry, Hospital de Clínicas de Porto Alegre, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Laboratory of Molecular Psychiatry, Hospital de Clínicas de Porto Alegre, Federal University of Rio Grande do Sul, Porto Alegre</wicri:regionArea>
<placeName>
<settlement type="city">Porto Alegre</settlement>
<region type="state">Rio Grande do Sul</region>
<settlement type="city">Porto Alegre</settlement>
</placeName>
<orgName type="university">Université fédérale du Rio Grande do Sul</orgName>
</affiliation>
</author>
<author>
<name sortKey="Lafer, Beny" sort="Lafer, Beny" uniqKey="Lafer B" first="Beny" last="Lafer">Beny Lafer</name>
<affiliation wicri:level="3">
<nlm:affiliation>Bipolar Disorder Research Program, Department of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Bipolar Disorder Research Program, Department of Psychiatry, University of São Paulo Medical School, São Paulo</wicri:regionArea>
<placeName>
<settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Larsen, Erik R" sort="Larsen, Erik R" uniqKey="Larsen E" first="Erik R" last="Larsen">Erik R. Larsen</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Affective Disorders, Q, Mood Disorders Research Unit, Aarhus University Hospital, Denmark.</nlm:affiliation>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Department of Affective Disorders, Q, Mood Disorders Research Unit, Aarhus University Hospital</wicri:regionArea>
<wicri:noRegion>Aarhus University Hospital</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Lewitzka, Ute" sort="Lewitzka, Ute" uniqKey="Lewitzka U" first="Ute" last="Lewitzka">Ute Lewitzka</name>
<affiliation wicri:level="3">
<nlm:affiliation>Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität, Dresden, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität, Dresden</wicri:regionArea>
<placeName>
<region type="land" nuts="1">Saxe (Land)</region>
<region type="district" nuts="2">District de Dresde</region>
<settlement type="city">Dresde</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Lopez Jaramillo, Carlos" sort="Lopez Jaramillo, Carlos" uniqKey="Lopez Jaramillo C" first="Carlos" last="Lopez-Jaramillo">Carlos Lopez-Jaramillo</name>
<affiliation wicri:level="1">
<nlm:affiliation>Mood Disorders Program, Fundacion San Vicente de Paul, Department of Psychiatry, Universidad de Antioquia, Medellín, Colombia.</nlm:affiliation>
<country xml:lang="fr">Colombie</country>
<wicri:regionArea>Mood Disorders Program, Fundacion San Vicente de Paul, Department of Psychiatry, Universidad de Antioquia, Medellín</wicri:regionArea>
<wicri:noRegion>Medellín</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Macqueen, Glenda" sort="Macqueen, Glenda" uniqKey="Macqueen G" first="Glenda" last="Macqueen">Glenda Macqueen</name>
<affiliation wicri:level="4">
<nlm:affiliation>Department of Psychiatry, Faculty of Medicine, University of Calgary, Calgary, AB, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Department of Psychiatry, Faculty of Medicine, University of Calgary, Calgary, AB</wicri:regionArea>
<orgName type="university">Université de Calgary</orgName>
<placeName>
<settlement type="city">Calgary</settlement>
<region type="state">Alberta</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Manchia, Mirko" sort="Manchia, Mirko" uniqKey="Manchia M" first="Mirko" last="Manchia">Mirko Manchia</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Psychiatry, Dalhousie University, Halifax, NS, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Department of Psychiatry, Dalhousie University, Halifax, NS</wicri:regionArea>
<wicri:noRegion>NS</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Marsh, Wendy" sort="Marsh, Wendy" uniqKey="Marsh W" first="Wendy" last="Marsh">Wendy Marsh</name>
<affiliation wicri:level="4">
<nlm:affiliation>Department of Psychiatry, University of Massachusetts, Worcester, MA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry, University of Massachusetts, Worcester, MA</wicri:regionArea>
<placeName>
<region type="state">Massachusetts</region>
<settlement type="city">Amherst (Massachusetts)</settlement>
</placeName>
<orgName type="university">Université du Massachusetts</orgName>
</affiliation>
</author>
<author>
<name sortKey="Martinez Cengotitabengoa, M Nica" sort="Martinez Cengotitabengoa, M Nica" uniqKey="Martinez Cengotitabengoa M" first="M Nica" last="Martinez-Cengotitabengoa">M Nica Martinez-Cengotitabengoa</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Psychiatry, University Hospital of Alava, University of the Basque Country, CIBERSAM, Vitoria, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Department of Psychiatry, University Hospital of Alava, University of the Basque Country, CIBERSAM, Vitoria</wicri:regionArea>
<wicri:noRegion>Vitoria</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Melle, Ingrid" sort="Melle, Ingrid" uniqKey="Melle I" first="Ingrid" last="Melle">Ingrid Melle</name>
<affiliation wicri:level="3">
<nlm:affiliation>NORMENT - K.G. Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, Oslo, Norway.</nlm:affiliation>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea>NORMENT - K.G. Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, Oslo</wicri:regionArea>
<placeName>
<settlement type="city">Oslo</settlement>
<region nuts="2">Østlandet</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Monteith, Scott" sort="Monteith, Scott" uniqKey="Monteith S" first="Scott" last="Monteith">Scott Monteith</name>
<affiliation wicri:level="2">
<nlm:affiliation>Michigan State University College of Human Medicine, Traverse City Campus, Traverse City, MI, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Michigan State University College of Human Medicine, Traverse City Campus, Traverse City, MI</wicri:regionArea>
<placeName>
<region type="state">Michigan</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Morken, Gunnar" sort="Morken, Gunnar" uniqKey="Morken G" first="Gunnar" last="Morken">Gunnar Morken</name>
<affiliation wicri:level="3">
<nlm:affiliation>Department of Neuroscience, Norwegian University of Science and Technology (NTNU), Trondheim, Norway; Department of Research and Development, Psychiatry, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.</nlm:affiliation>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea>Department of Neuroscience, Norwegian University of Science and Technology (NTNU), Trondheim, Norway; Department of Research and Development, Psychiatry, St. Olavs Hospital, Trondheim University Hospital, Trondheim</wicri:regionArea>
<placeName>
<settlement type="city">Trondheim</settlement>
<region type="région" nuts="2">Trøndelag</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Munoz, Rodrigo" sort="Munoz, Rodrigo" uniqKey="Munoz R" first="Rodrigo" last="Munoz">Rodrigo Munoz</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Psychiatry, University of California San Diego, San Diego, CA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry, University of California San Diego, San Diego, CA</wicri:regionArea>
<placeName>
<region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Nery, Fabiano G" sort="Nery, Fabiano G" uniqKey="Nery F" first="Fabiano G" last="Nery">Fabiano G. Nery</name>
<affiliation wicri:level="3">
<nlm:affiliation>Bipolar Disorder Research Program, Department of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Bipolar Disorder Research Program, Department of Psychiatry, University of São Paulo Medical School, São Paulo</wicri:regionArea>
<placeName>
<settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="O Donovan, Claire" sort="O Donovan, Claire" uniqKey="O Donovan C" first="Claire" last="O'Donovan">Claire O'Donovan</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Psychiatry, Dalhousie University, Halifax, NS, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Department of Psychiatry, Dalhousie University, Halifax, NS</wicri:regionArea>
<wicri:noRegion>NS</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Osher, Yamima" sort="Osher, Yamima" uniqKey="Osher Y" first="Yamima" last="Osher">Yamima Osher</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Psychiatry, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva Mental Health Center, Beer Sheva, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Department of Psychiatry, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva Mental Health Center, Beer Sheva</wicri:regionArea>
<wicri:noRegion>Beer Sheva</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Pfennig, Andrea" sort="Pfennig, Andrea" uniqKey="Pfennig A" first="Andrea" last="Pfennig">Andrea Pfennig</name>
<affiliation wicri:level="3">
<nlm:affiliation>Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität, Dresden, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität, Dresden</wicri:regionArea>
<placeName>
<region type="land" nuts="1">Saxe (Land)</region>
<region type="district" nuts="2">District de Dresde</region>
<settlement type="city">Dresde</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Quiroz, Danilo" sort="Quiroz, Danilo" uniqKey="Quiroz D" first="Danilo" last="Quiroz">Danilo Quiroz</name>
<affiliation wicri:level="1">
<nlm:affiliation>Deparment of Psychiatry, Diego Portales University, Santiago, Chile.</nlm:affiliation>
<country xml:lang="fr">Chili</country>
<wicri:regionArea>Deparment of Psychiatry, Diego Portales University, Santiago</wicri:regionArea>
<wicri:noRegion>Santiago</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Ramesar, Raj" sort="Ramesar, Raj" uniqKey="Ramesar R" first="Raj" last="Ramesar">Raj Ramesar</name>
<affiliation wicri:level="1">
<nlm:affiliation>UCT/MRC Human Genetics Research Unit, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.</nlm:affiliation>
<country xml:lang="fr">Afrique du Sud</country>
<wicri:regionArea>UCT/MRC Human Genetics Research Unit, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town</wicri:regionArea>
<wicri:noRegion>Cape Town</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Rasgon, Natalie" sort="Rasgon, Natalie" uniqKey="Rasgon N" first="Natalie" last="Rasgon">Natalie Rasgon</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Palo Alto, CA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Palo Alto, CA</wicri:regionArea>
<placeName>
<region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Reif, Andreas" sort="Reif, Andreas" uniqKey="Reif A" first="Andreas" last="Reif">Andreas Reif</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Goethe-University Frankfurt am Main, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Goethe-University Frankfurt am Main</wicri:regionArea>
<wicri:noRegion>Goethe-University Frankfurt am Main</wicri:noRegion>
<wicri:noRegion>Goethe-University Frankfurt am Main</wicri:noRegion>
<wicri:noRegion>Goethe-University Frankfurt am Main</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Ritter, Philipp" sort="Ritter, Philipp" uniqKey="Ritter P" first="Philipp" last="Ritter">Philipp Ritter</name>
<affiliation wicri:level="3">
<nlm:affiliation>Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität, Dresden, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität, Dresden</wicri:regionArea>
<placeName>
<region type="land" nuts="1">Saxe (Land)</region>
<region type="district" nuts="2">District de Dresde</region>
<settlement type="city">Dresde</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Rybakowski, Janusz K" sort="Rybakowski, Janusz K" uniqKey="Rybakowski J" first="Janusz K" last="Rybakowski">Janusz K. Rybakowski</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland.</nlm:affiliation>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea>Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan</wicri:regionArea>
<wicri:noRegion>Poznan</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Sagduyu, Kemal" sort="Sagduyu, Kemal" uniqKey="Sagduyu K" first="Kemal" last="Sagduyu">Kemal Sagduyu</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Psychiatry, University of Missouri Kansas City School of Medicine, Kansas City, MO, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry, University of Missouri Kansas City School of Medicine, Kansas City, MO</wicri:regionArea>
<placeName>
<region type="state">Missouri (État)</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Miranda Scippa, Angela" sort="Miranda Scippa, Angela" uniqKey="Miranda Scippa A" first="Ângela" last="Miranda-Scippa">Ângela Miranda-Scippa</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Neuroscience and Mental Health, Federal University of Bahia, Salvador, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Department of Neuroscience and Mental Health, Federal University of Bahia, Salvador</wicri:regionArea>
<wicri:noRegion>Salvador</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Severus, Emanuel" sort="Severus, Emanuel" uniqKey="Severus E" first="Emanuel" last="Severus">Emanuel Severus</name>
<affiliation wicri:level="3">
<nlm:affiliation>Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität, Dresden, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität, Dresden</wicri:regionArea>
<placeName>
<region type="land" nuts="1">Saxe (Land)</region>
<region type="district" nuts="2">District de Dresde</region>
<settlement type="city">Dresde</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Simhandl, Christian" sort="Simhandl, Christian" uniqKey="Simhandl C" first="Christian" last="Simhandl">Christian Simhandl</name>
<affiliation wicri:level="1">
<nlm:affiliation>BIPOLAR Zentrum Wiener Neustadt, Wiener Neustadt, Austria.</nlm:affiliation>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>BIPOLAR Zentrum Wiener Neustadt, Wiener Neustadt</wicri:regionArea>
<wicri:noRegion>Wiener Neustadt</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Stein, Dan J" sort="Stein, Dan J" uniqKey="Stein D" first="Dan J" last="Stein">Dan J. Stein</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Psychiatry, University of Cape Town, Cape Town, South Africa.</nlm:affiliation>
<country xml:lang="fr">Afrique du Sud</country>
<wicri:regionArea>Department of Psychiatry, University of Cape Town, Cape Town</wicri:regionArea>
<wicri:noRegion>Cape Town</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Strejilevich, Sergio" sort="Strejilevich, Sergio" uniqKey="Strejilevich S" first="Sergio" last="Strejilevich">Sergio Strejilevich</name>
<affiliation wicri:level="1">
<nlm:affiliation>Bipolar Disorder Program, Neuroscience Institute, Favaloro University, Buenos Aires, Argentina.</nlm:affiliation>
<country xml:lang="fr">Argentine</country>
<wicri:regionArea>Bipolar Disorder Program, Neuroscience Institute, Favaloro University, Buenos Aires</wicri:regionArea>
<wicri:noRegion>Buenos Aires</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Sulaiman, Ahmad Hatim" sort="Sulaiman, Ahmad Hatim" uniqKey="Sulaiman A" first="Ahmad Hatim" last="Sulaiman">Ahmad Hatim Sulaiman</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Psychological Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.</nlm:affiliation>
<country xml:lang="fr">Malaisie</country>
<wicri:regionArea>Department of Psychological Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur</wicri:regionArea>
<wicri:noRegion>Kuala Lumpur</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Suominen, Kirsi" sort="Suominen, Kirsi" uniqKey="Suominen K" first="Kirsi" last="Suominen">Kirsi Suominen</name>
<affiliation wicri:level="1">
<nlm:affiliation>City of Helsinki, Department of Social Services and Health Care, Psychiatry, Helsinki, Finland.</nlm:affiliation>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>City of Helsinki, Department of Social Services and Health Care, Psychiatry, Helsinki</wicri:regionArea>
<wicri:noRegion>Helsinki</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Tagata, Hiromi" sort="Tagata, Hiromi" uniqKey="Tagata H" first="Hiromi" last="Tagata">Hiromi Tagata</name>
<affiliation wicri:level="3">
<nlm:affiliation>Department of Psychiatry, Tokyo Metropolitan Matsuzawa Hospital, Setagaya, Tokyo, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Psychiatry, Tokyo Metropolitan Matsuzawa Hospital, Setagaya, Tokyo</wicri:regionArea>
<placeName>
<settlement type="city">Tokyo</settlement>
<region type="région">Région de Kantō</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Tatebayashi, Yoshitaka" sort="Tatebayashi, Yoshitaka" uniqKey="Tatebayashi Y" first="Yoshitaka" last="Tatebayashi">Yoshitaka Tatebayashi</name>
<affiliation wicri:level="3">
<nlm:affiliation>Schizophrenia & Affective Disorders Research Project, Tokyo Metropolitan Institute of Medical Science, Seatagaya, Tokyo, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Schizophrenia & Affective Disorders Research Project, Tokyo Metropolitan Institute of Medical Science, Seatagaya, Tokyo</wicri:regionArea>
<placeName>
<settlement type="city">Tokyo</settlement>
<region type="région">Région de Kantō</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Torrent, Carla" sort="Torrent, Carla" uniqKey="Torrent C" first="Carla" last="Torrent">Carla Torrent</name>
<affiliation wicri:level="1">
<nlm:affiliation>Bipolar Disorders Program, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Catalonia, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Bipolar Disorders Program, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Catalonia</wicri:regionArea>
<wicri:noRegion>Catalonia</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Vieta, Eduard" sort="Vieta, Eduard" uniqKey="Vieta E" first="Eduard" last="Vieta">Eduard Vieta</name>
<affiliation wicri:level="1">
<nlm:affiliation>Bipolar Disorders Program, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Catalonia, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
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<title xml:lang="en">Influence of light exposure during early life on the age of onset of bipolar disorder.</title>
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<country xml:lang="fr">Israël</country>
<wicri:regionArea>Department of Psychiatry, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva Mental Health Center, Beer Sheva</wicri:regionArea>
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<country xml:lang="fr">Australie</country>
<wicri:regionArea>IMPACT Strategic Research Centre, School of Medicine, Deakin University, Geelong, Victoria 3220, Australia; Department of Psychiatry, ORYGEN Youth Health Research Centre, Centre for Youth Mental Health and the Florey Institute for Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria 3052</wicri:regionArea>
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<wicri:regionArea>Department of Molecular Medicine and Department of Mental Health (DAI), University of Siena and University of Siena Medical Center (AOUS), Siena</wicri:regionArea>
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<nlm:affiliation>Department of Psychiatry, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva Mental Health Center, Beer Sheva, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Department of Psychiatry, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva Mental Health Center, Beer Sheva</wicri:regionArea>
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<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität, Dresden</wicri:regionArea>
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<country xml:lang="fr">Australie</country>
<wicri:regionArea>IMPACT Strategic Research Centre, School of Medicine, Deakin University, Geelong, Victoria 3220, Australia; Department of Psychiatry, University of Melbourne, Parkville, Victoria 3052</wicri:regionArea>
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<nlm:affiliation>Department of Molecular Medicine and Department of Mental Health (DAI), University of Siena and University of Siena Medical Center (AOUS), Siena, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
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<nlm:affiliation>Department of Psychiatry & Psychology, Mayo Clinic Depression Center, Mayo Clinic, Rochester, MN, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry & Psychology, Mayo Clinic Depression Center, Mayo Clinic, Rochester, MN</wicri:regionArea>
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<name sortKey="Fountoulakis, Kostas N" sort="Fountoulakis, Kostas N" uniqKey="Fountoulakis K" first="Kostas N" last="Fountoulakis">Kostas N. Fountoulakis</name>
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<nlm:affiliation>3rd Department of Psychiatry, Division of Neurosciences, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.</nlm:affiliation>
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<nlm:affiliation>Department of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Palo Alto, CA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
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<nlm:affiliation>Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.</nlm:affiliation>
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</affiliation>
</author>
<author>
<name sortKey="Kapczinski, Flavio" sort="Kapczinski, Flavio" uniqKey="Kapczinski F" first="Flávio" last="Kapczinski">Flávio Kapczinski</name>
<affiliation wicri:level="4">
<nlm:affiliation>Laboratory of Molecular Psychiatry, Hospital de Clínicas de Porto Alegre, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Laboratory of Molecular Psychiatry, Hospital de Clínicas de Porto Alegre, Federal University of Rio Grande do Sul, Porto Alegre</wicri:regionArea>
<placeName>
<settlement type="city">Porto Alegre</settlement>
<region type="state">Rio Grande do Sul</region>
<settlement type="city">Porto Alegre</settlement>
</placeName>
<orgName type="university">Université fédérale du Rio Grande do Sul</orgName>
</affiliation>
</author>
<author>
<name sortKey="Kliwicki, Sebastian" sort="Kliwicki, Sebastian" uniqKey="Kliwicki S" first="Sebastian" last="Kliwicki">Sebastian Kliwicki</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland.</nlm:affiliation>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea>Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan</wicri:regionArea>
<wicri:noRegion>Poznan</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Konig, Barbara" sort="Konig, Barbara" uniqKey="Konig B" first="Barbara" last="König">Barbara König</name>
<affiliation wicri:level="1">
<nlm:affiliation>BIPOLAR Zentrum Wiener Neustadt, Wiener Neustadt, Austria.</nlm:affiliation>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>BIPOLAR Zentrum Wiener Neustadt, Wiener Neustadt</wicri:regionArea>
<wicri:noRegion>Wiener Neustadt</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Krogh, Rikke" sort="Krogh, Rikke" uniqKey="Krogh R" first="Rikke" last="Krogh">Rikke Krogh</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Affective Disorders, Q, Mood Disorders Research Unit, Aarhus University Hospital, Denmark.</nlm:affiliation>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Department of Affective Disorders, Q, Mood Disorders Research Unit, Aarhus University Hospital</wicri:regionArea>
<wicri:noRegion>Aarhus University Hospital</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Kunz, Mauricio" sort="Kunz, Mauricio" uniqKey="Kunz M" first="Mauricio" last="Kunz">Mauricio Kunz</name>
<affiliation wicri:level="4">
<nlm:affiliation>Laboratory of Molecular Psychiatry, Hospital de Clínicas de Porto Alegre, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Laboratory of Molecular Psychiatry, Hospital de Clínicas de Porto Alegre, Federal University of Rio Grande do Sul, Porto Alegre</wicri:regionArea>
<placeName>
<settlement type="city">Porto Alegre</settlement>
<region type="state">Rio Grande do Sul</region>
<settlement type="city">Porto Alegre</settlement>
</placeName>
<orgName type="university">Université fédérale du Rio Grande do Sul</orgName>
</affiliation>
</author>
<author>
<name sortKey="Lafer, Beny" sort="Lafer, Beny" uniqKey="Lafer B" first="Beny" last="Lafer">Beny Lafer</name>
<affiliation wicri:level="3">
<nlm:affiliation>Bipolar Disorder Research Program, Department of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Bipolar Disorder Research Program, Department of Psychiatry, University of São Paulo Medical School, São Paulo</wicri:regionArea>
<placeName>
<settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Larsen, Erik R" sort="Larsen, Erik R" uniqKey="Larsen E" first="Erik R" last="Larsen">Erik R. Larsen</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Affective Disorders, Q, Mood Disorders Research Unit, Aarhus University Hospital, Denmark.</nlm:affiliation>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Department of Affective Disorders, Q, Mood Disorders Research Unit, Aarhus University Hospital</wicri:regionArea>
<wicri:noRegion>Aarhus University Hospital</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Lewitzka, Ute" sort="Lewitzka, Ute" uniqKey="Lewitzka U" first="Ute" last="Lewitzka">Ute Lewitzka</name>
<affiliation wicri:level="3">
<nlm:affiliation>Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität, Dresden, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität, Dresden</wicri:regionArea>
<placeName>
<region type="land" nuts="1">Saxe (Land)</region>
<region type="district" nuts="2">District de Dresde</region>
<settlement type="city">Dresde</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Lopez Jaramillo, Carlos" sort="Lopez Jaramillo, Carlos" uniqKey="Lopez Jaramillo C" first="Carlos" last="Lopez-Jaramillo">Carlos Lopez-Jaramillo</name>
<affiliation wicri:level="1">
<nlm:affiliation>Mood Disorders Program, Fundacion San Vicente de Paul, Department of Psychiatry, Universidad de Antioquia, Medellín, Colombia.</nlm:affiliation>
<country xml:lang="fr">Colombie</country>
<wicri:regionArea>Mood Disorders Program, Fundacion San Vicente de Paul, Department of Psychiatry, Universidad de Antioquia, Medellín</wicri:regionArea>
<wicri:noRegion>Medellín</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Macqueen, Glenda" sort="Macqueen, Glenda" uniqKey="Macqueen G" first="Glenda" last="Macqueen">Glenda Macqueen</name>
<affiliation wicri:level="4">
<nlm:affiliation>Department of Psychiatry, Faculty of Medicine, University of Calgary, Calgary, AB, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Department of Psychiatry, Faculty of Medicine, University of Calgary, Calgary, AB</wicri:regionArea>
<orgName type="university">Université de Calgary</orgName>
<placeName>
<settlement type="city">Calgary</settlement>
<region type="state">Alberta</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Manchia, Mirko" sort="Manchia, Mirko" uniqKey="Manchia M" first="Mirko" last="Manchia">Mirko Manchia</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Psychiatry, Dalhousie University, Halifax, NS, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Department of Psychiatry, Dalhousie University, Halifax, NS</wicri:regionArea>
<wicri:noRegion>NS</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Marsh, Wendy" sort="Marsh, Wendy" uniqKey="Marsh W" first="Wendy" last="Marsh">Wendy Marsh</name>
<affiliation wicri:level="4">
<nlm:affiliation>Department of Psychiatry, University of Massachusetts, Worcester, MA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry, University of Massachusetts, Worcester, MA</wicri:regionArea>
<placeName>
<region type="state">Massachusetts</region>
<settlement type="city">Amherst (Massachusetts)</settlement>
</placeName>
<orgName type="university">Université du Massachusetts</orgName>
</affiliation>
</author>
<author>
<name sortKey="Martinez Cengotitabengoa, M Nica" sort="Martinez Cengotitabengoa, M Nica" uniqKey="Martinez Cengotitabengoa M" first="M Nica" last="Martinez-Cengotitabengoa">M Nica Martinez-Cengotitabengoa</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Psychiatry, University Hospital of Alava, University of the Basque Country, CIBERSAM, Vitoria, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Department of Psychiatry, University Hospital of Alava, University of the Basque Country, CIBERSAM, Vitoria</wicri:regionArea>
<wicri:noRegion>Vitoria</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Melle, Ingrid" sort="Melle, Ingrid" uniqKey="Melle I" first="Ingrid" last="Melle">Ingrid Melle</name>
<affiliation wicri:level="3">
<nlm:affiliation>NORMENT - K.G. Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, Oslo, Norway.</nlm:affiliation>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea>NORMENT - K.G. Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, Oslo</wicri:regionArea>
<placeName>
<settlement type="city">Oslo</settlement>
<region nuts="2">Østlandet</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Monteith, Scott" sort="Monteith, Scott" uniqKey="Monteith S" first="Scott" last="Monteith">Scott Monteith</name>
<affiliation wicri:level="2">
<nlm:affiliation>Michigan State University College of Human Medicine, Traverse City Campus, Traverse City, MI, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Michigan State University College of Human Medicine, Traverse City Campus, Traverse City, MI</wicri:regionArea>
<placeName>
<region type="state">Michigan</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Morken, Gunnar" sort="Morken, Gunnar" uniqKey="Morken G" first="Gunnar" last="Morken">Gunnar Morken</name>
<affiliation wicri:level="3">
<nlm:affiliation>Department of Neuroscience, Norwegian University of Science and Technology (NTNU), Trondheim, Norway; Department of Research and Development, Psychiatry, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.</nlm:affiliation>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea>Department of Neuroscience, Norwegian University of Science and Technology (NTNU), Trondheim, Norway; Department of Research and Development, Psychiatry, St. Olavs Hospital, Trondheim University Hospital, Trondheim</wicri:regionArea>
<placeName>
<settlement type="city">Trondheim</settlement>
<region type="région" nuts="2">Trøndelag</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Munoz, Rodrigo" sort="Munoz, Rodrigo" uniqKey="Munoz R" first="Rodrigo" last="Munoz">Rodrigo Munoz</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Psychiatry, University of California San Diego, San Diego, CA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry, University of California San Diego, San Diego, CA</wicri:regionArea>
<placeName>
<region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Nery, Fabiano G" sort="Nery, Fabiano G" uniqKey="Nery F" first="Fabiano G" last="Nery">Fabiano G. Nery</name>
<affiliation wicri:level="3">
<nlm:affiliation>Bipolar Disorder Research Program, Department of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Bipolar Disorder Research Program, Department of Psychiatry, University of São Paulo Medical School, São Paulo</wicri:regionArea>
<placeName>
<settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="O Donovan, Claire" sort="O Donovan, Claire" uniqKey="O Donovan C" first="Claire" last="O'Donovan">Claire O'Donovan</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Psychiatry, Dalhousie University, Halifax, NS, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Department of Psychiatry, Dalhousie University, Halifax, NS</wicri:regionArea>
<wicri:noRegion>NS</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Osher, Yamima" sort="Osher, Yamima" uniqKey="Osher Y" first="Yamima" last="Osher">Yamima Osher</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Psychiatry, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva Mental Health Center, Beer Sheva, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Department of Psychiatry, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva Mental Health Center, Beer Sheva</wicri:regionArea>
<wicri:noRegion>Beer Sheva</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Pfennig, Andrea" sort="Pfennig, Andrea" uniqKey="Pfennig A" first="Andrea" last="Pfennig">Andrea Pfennig</name>
<affiliation wicri:level="3">
<nlm:affiliation>Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität, Dresden, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität, Dresden</wicri:regionArea>
<placeName>
<region type="land" nuts="1">Saxe (Land)</region>
<region type="district" nuts="2">District de Dresde</region>
<settlement type="city">Dresde</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Quiroz, Danilo" sort="Quiroz, Danilo" uniqKey="Quiroz D" first="Danilo" last="Quiroz">Danilo Quiroz</name>
<affiliation wicri:level="1">
<nlm:affiliation>Deparment of Psychiatry, Diego Portales University, Santiago, Chile.</nlm:affiliation>
<country xml:lang="fr">Chili</country>
<wicri:regionArea>Deparment of Psychiatry, Diego Portales University, Santiago</wicri:regionArea>
<wicri:noRegion>Santiago</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Ramesar, Raj" sort="Ramesar, Raj" uniqKey="Ramesar R" first="Raj" last="Ramesar">Raj Ramesar</name>
<affiliation wicri:level="1">
<nlm:affiliation>UCT/MRC Human Genetics Research Unit, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.</nlm:affiliation>
<country xml:lang="fr">Afrique du Sud</country>
<wicri:regionArea>UCT/MRC Human Genetics Research Unit, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town</wicri:regionArea>
<wicri:noRegion>Cape Town</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Rasgon, Natalie" sort="Rasgon, Natalie" uniqKey="Rasgon N" first="Natalie" last="Rasgon">Natalie Rasgon</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Palo Alto, CA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Palo Alto, CA</wicri:regionArea>
<placeName>
<region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Reif, Andreas" sort="Reif, Andreas" uniqKey="Reif A" first="Andreas" last="Reif">Andreas Reif</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Goethe-University Frankfurt am Main, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Goethe-University Frankfurt am Main</wicri:regionArea>
<wicri:noRegion>Goethe-University Frankfurt am Main</wicri:noRegion>
<wicri:noRegion>Goethe-University Frankfurt am Main</wicri:noRegion>
<wicri:noRegion>Goethe-University Frankfurt am Main</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Ritter, Philipp" sort="Ritter, Philipp" uniqKey="Ritter P" first="Philipp" last="Ritter">Philipp Ritter</name>
<affiliation wicri:level="3">
<nlm:affiliation>Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität, Dresden, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität, Dresden</wicri:regionArea>
<placeName>
<region type="land" nuts="1">Saxe (Land)</region>
<region type="district" nuts="2">District de Dresde</region>
<settlement type="city">Dresde</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Rybakowski, Janusz K" sort="Rybakowski, Janusz K" uniqKey="Rybakowski J" first="Janusz K" last="Rybakowski">Janusz K. Rybakowski</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland.</nlm:affiliation>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea>Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan</wicri:regionArea>
<wicri:noRegion>Poznan</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Sagduyu, Kemal" sort="Sagduyu, Kemal" uniqKey="Sagduyu K" first="Kemal" last="Sagduyu">Kemal Sagduyu</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Psychiatry, University of Missouri Kansas City School of Medicine, Kansas City, MO, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry, University of Missouri Kansas City School of Medicine, Kansas City, MO</wicri:regionArea>
<placeName>
<region type="state">Missouri (État)</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Miranda Scippa, Angela" sort="Miranda Scippa, Angela" uniqKey="Miranda Scippa A" first="Ângela" last="Miranda-Scippa">Ângela Miranda-Scippa</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Neuroscience and Mental Health, Federal University of Bahia, Salvador, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Department of Neuroscience and Mental Health, Federal University of Bahia, Salvador</wicri:regionArea>
<wicri:noRegion>Salvador</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Severus, Emanuel" sort="Severus, Emanuel" uniqKey="Severus E" first="Emanuel" last="Severus">Emanuel Severus</name>
<affiliation wicri:level="3">
<nlm:affiliation>Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität, Dresden, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität, Dresden</wicri:regionArea>
<placeName>
<region type="land" nuts="1">Saxe (Land)</region>
<region type="district" nuts="2">District de Dresde</region>
<settlement type="city">Dresde</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Simhandl, Christian" sort="Simhandl, Christian" uniqKey="Simhandl C" first="Christian" last="Simhandl">Christian Simhandl</name>
<affiliation wicri:level="1">
<nlm:affiliation>BIPOLAR Zentrum Wiener Neustadt, Wiener Neustadt, Austria.</nlm:affiliation>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>BIPOLAR Zentrum Wiener Neustadt, Wiener Neustadt</wicri:regionArea>
<wicri:noRegion>Wiener Neustadt</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Stein, Dan J" sort="Stein, Dan J" uniqKey="Stein D" first="Dan J" last="Stein">Dan J. Stein</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Psychiatry, University of Cape Town, Cape Town, South Africa.</nlm:affiliation>
<country xml:lang="fr">Afrique du Sud</country>
<wicri:regionArea>Department of Psychiatry, University of Cape Town, Cape Town</wicri:regionArea>
<wicri:noRegion>Cape Town</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Strejilevich, Sergio" sort="Strejilevich, Sergio" uniqKey="Strejilevich S" first="Sergio" last="Strejilevich">Sergio Strejilevich</name>
<affiliation wicri:level="1">
<nlm:affiliation>Bipolar Disorder Program, Neuroscience Institute, Favaloro University, Buenos Aires, Argentina.</nlm:affiliation>
<country xml:lang="fr">Argentine</country>
<wicri:regionArea>Bipolar Disorder Program, Neuroscience Institute, Favaloro University, Buenos Aires</wicri:regionArea>
<wicri:noRegion>Buenos Aires</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Sulaiman, Ahmad Hatim" sort="Sulaiman, Ahmad Hatim" uniqKey="Sulaiman A" first="Ahmad Hatim" last="Sulaiman">Ahmad Hatim Sulaiman</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Psychological Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.</nlm:affiliation>
<country xml:lang="fr">Malaisie</country>
<wicri:regionArea>Department of Psychological Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur</wicri:regionArea>
<wicri:noRegion>Kuala Lumpur</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Suominen, Kirsi" sort="Suominen, Kirsi" uniqKey="Suominen K" first="Kirsi" last="Suominen">Kirsi Suominen</name>
<affiliation wicri:level="1">
<nlm:affiliation>City of Helsinki, Department of Social Services and Health Care, Psychiatry, Helsinki, Finland.</nlm:affiliation>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>City of Helsinki, Department of Social Services and Health Care, Psychiatry, Helsinki</wicri:regionArea>
<wicri:noRegion>Helsinki</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Tagata, Hiromi" sort="Tagata, Hiromi" uniqKey="Tagata H" first="Hiromi" last="Tagata">Hiromi Tagata</name>
<affiliation wicri:level="3">
<nlm:affiliation>Department of Psychiatry, Tokyo Metropolitan Matsuzawa Hospital, Setagaya, Tokyo, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Psychiatry, Tokyo Metropolitan Matsuzawa Hospital, Setagaya, Tokyo</wicri:regionArea>
<placeName>
<settlement type="city">Tokyo</settlement>
<region type="région">Région de Kantō</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Tatebayashi, Yoshitaka" sort="Tatebayashi, Yoshitaka" uniqKey="Tatebayashi Y" first="Yoshitaka" last="Tatebayashi">Yoshitaka Tatebayashi</name>
<affiliation wicri:level="3">
<nlm:affiliation>Schizophrenia & Affective Disorders Research Project, Tokyo Metropolitan Institute of Medical Science, Seatagaya, Tokyo, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Schizophrenia & Affective Disorders Research Project, Tokyo Metropolitan Institute of Medical Science, Seatagaya, Tokyo</wicri:regionArea>
<placeName>
<settlement type="city">Tokyo</settlement>
<region type="région">Région de Kantō</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Torrent, Carla" sort="Torrent, Carla" uniqKey="Torrent C" first="Carla" last="Torrent">Carla Torrent</name>
<affiliation wicri:level="1">
<nlm:affiliation>Bipolar Disorders Program, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Catalonia, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Bipolar Disorders Program, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Catalonia</wicri:regionArea>
<wicri:noRegion>Catalonia</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Vieta, Eduard" sort="Vieta, Eduard" uniqKey="Vieta E" first="Eduard" last="Vieta">Eduard Vieta</name>
<affiliation wicri:level="1">
<nlm:affiliation>Bipolar Disorders Program, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Catalonia, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
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<name sortKey="Viswanath, Biju" sort="Viswanath, Biju" uniqKey="Viswanath B" first="Biju" last="Viswanath">Biju Viswanath</name>
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<nlm:affiliation>Department of Psychiatry, NIMHANS, Bangalore 560029, India.</nlm:affiliation>
<country xml:lang="fr">Inde</country>
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<name sortKey="Zetin, Mark" sort="Zetin, Mark" uniqKey="Zetin M" first="Mark" last="Zetin">Mark Zetin</name>
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<nlm:affiliation>Department of Psychology, Chapman University, Orange, CA, USA.</nlm:affiliation>
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<wicri:regionArea>Department of Psychology, Chapman University, Orange, CA</wicri:regionArea>
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</placeName>
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<author>
<name sortKey="Whybrow, Peter C" sort="Whybrow, Peter C" uniqKey="Whybrow P" first="Peter C" last="Whybrow">Peter C. Whybrow</name>
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<nlm:affiliation>Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior University of California Los Angeles (UCLA), Los Angeles, CA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior University of California Los Angeles (UCLA), Los Angeles, CA</wicri:regionArea>
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<region type="state">Californie</region>
</placeName>
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<series>
<title level="j">Journal of psychiatric research</title>
<idno type="eISSN">1879-1379</idno>
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<term>Adult</term>
<term>Age of Onset</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Bipolar Disorder (epidemiology)</term>
<term>Climate</term>
<term>Cohort Studies</term>
<term>Databases, Factual (statistics & numerical data)</term>
<term>Female</term>
<term>Humans</term>
<term>International Cooperation</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Seasons</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr">
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Bases de données factuelles ()</term>
<term>Climat</term>
<term>Coopération internationale</term>
<term>Femelle</term>
<term>Humains</term>
<term>Mâle</term>
<term>Saisons</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Trouble bipolaire (épidémiologie)</term>
<term>Âge de début</term>
<term>Études de cohortes</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en">
<term>Bipolar Disorder</term>
</keywords>
<keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en">
<term>Databases, Factual</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr">
<term>Trouble bipolaire</term>
</keywords>
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<term>Adult</term>
<term>Age of Onset</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Climate</term>
<term>Cohort Studies</term>
<term>Female</term>
<term>Humans</term>
<term>International Cooperation</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Seasons</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr">
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Bases de données factuelles</term>
<term>Climat</term>
<term>Coopération internationale</term>
<term>Femelle</term>
<term>Humains</term>
<term>Mâle</term>
<term>Saisons</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Âge de début</term>
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<front>
<div type="abstract" xml:lang="en">Environmental conditions early in life may imprint the circadian system and influence response to environmental signals later in life. We previously determined that a large springtime increase in solar insolation at the onset location was associated with a younger age of onset of bipolar disorder, especially with a family history of mood disorders. This study investigated whether the hours of daylight at the birth location affected this association.</div>
</front>
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<MedlineCitation Status="MEDLINE" Owner="NLM">
<PMID Version="1">25862378</PMID>
<DateCreated>
<Year>2015</Year>
<Month>04</Month>
<Day>20</Day>
</DateCreated>
<DateCompleted>
<Year>2016</Year>
<Month>01</Month>
<Day>04</Day>
</DateCompleted>
<DateRevised>
<Year>2015</Year>
<Month>04</Month>
<Day>20</Day>
</DateRevised>
<Article PubModel="Print-Electronic">
<Journal>
<ISSN IssnType="Electronic">1879-1379</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>64</Volume>
<PubDate>
<Year>2015</Year>
<Month>May</Month>
</PubDate>
</JournalIssue>
<Title>Journal of psychiatric research</Title>
<ISOAbbreviation>J Psychiatr Res</ISOAbbreviation>
</Journal>
<ArticleTitle>Influence of light exposure during early life on the age of onset of bipolar disorder.</ArticleTitle>
<Pagination>
<MedlinePgn>1-8</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jpsychires.2015.03.013</ELocationID>
<ELocationID EIdType="pii" ValidYN="Y">S0022-3956(15)00082-5</ELocationID>
<Abstract>
<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Environmental conditions early in life may imprint the circadian system and influence response to environmental signals later in life. We previously determined that a large springtime increase in solar insolation at the onset location was associated with a younger age of onset of bipolar disorder, especially with a family history of mood disorders. This study investigated whether the hours of daylight at the birth location affected this association.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Data collected previously at 36 collection sites from 23 countries were available for 3896 patients with bipolar I disorder, born between latitudes of 1.4 N and 70.7 N, and 1.2 S and 41.3 S. Hours of daylight variables for the birth location were added to a base model to assess the relation between the age of onset and solar insolation.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">More hours of daylight at the birth location during early life was associated with an older age of onset, suggesting reduced vulnerability to the future circadian challenge of the springtime increase in solar insolation at the onset location. Addition of the minimum of the average monthly hours of daylight during the first 3 months of life improved the base model, with a significant positive relationship to age of onset. Coefficients for all other variables remained stable, significant and consistent with the base model.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Light exposure during early life may have important consequences for those who are susceptible to bipolar disorder, especially at latitudes with little natural light in winter. This study indirectly supports the concept that early life exposure to light may affect the long term adaptability to respond to a circadian challenge later in life.</AbstractText>
<CopyrightInformation>Copyright © 2015 Elsevier Ltd. All rights reserved.</CopyrightInformation>
</Abstract>
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<LastName>Bauer</LastName>
<ForeName>Michael</ForeName>
<Initials>M</Initials>
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<Affiliation>Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität, Dresden, Germany. Electronic address: michael.bauer@uniklinikum-dresden.de.</Affiliation>
</AffiliationInfo>
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<ForeName>Tasha</ForeName>
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</AffiliationInfo>
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<LastName>Andreassen</LastName>
<ForeName>Ole A</ForeName>
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<Affiliation>NORMENT - K.G. Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, Oslo, Norway.</Affiliation>
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<LastName>Angelopoulos</LastName>
<ForeName>Elias</ForeName>
<Initials>E</Initials>
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<Affiliation>Department of Psychiatry, University of Athens Medical School, Eginition Hospital, Athens, Greece.</Affiliation>
</AffiliationInfo>
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<LastName>Ardau</LastName>
<ForeName>Raffaella</ForeName>
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</AffiliationInfo>
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<LastName>Bossini</LastName>
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<LastName>Bersudsky</LastName>
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<LastName>Dodd</LastName>
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<Initials>A</Initials>
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<Affiliation>3rd Department of Psychiatry, Division of Neurosciences, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.</Affiliation>
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<LastName>Isometsä</LastName>
<ForeName>Erkki T</ForeName>
<Initials>ET</Initials>
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<Affiliation>Department of Psychiatry, Institute of Clinical Medicine, University of Helsinki, Finland; National Institute for Health and Welfare, Helsinki, Finland.</Affiliation>
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<Affiliation>Laboratory of Molecular Psychiatry, Hospital de Clínicas de Porto Alegre, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.</Affiliation>
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<Affiliation>Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland.</Affiliation>
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<LastName>König</LastName>
<ForeName>Barbara</ForeName>
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<LastName>Krogh</LastName>
<ForeName>Rikke</ForeName>
<Initials>R</Initials>
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<Affiliation>Department of Affective Disorders, Q, Mood Disorders Research Unit, Aarhus University Hospital, Denmark.</Affiliation>
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<LastName>Kunz</LastName>
<ForeName>Mauricio</ForeName>
<Initials>M</Initials>
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<Affiliation>Laboratory of Molecular Psychiatry, Hospital de Clínicas de Porto Alegre, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.</Affiliation>
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</Author>
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<LastName>Lafer</LastName>
<ForeName>Beny</ForeName>
<Initials>B</Initials>
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<Affiliation>Bipolar Disorder Research Program, Department of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil.</Affiliation>
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</Author>
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<LastName>Larsen</LastName>
<ForeName>Erik R</ForeName>
<Initials>ER</Initials>
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<Affiliation>Department of Affective Disorders, Q, Mood Disorders Research Unit, Aarhus University Hospital, Denmark.</Affiliation>
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</Author>
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<LastName>Lewitzka</LastName>
<ForeName>Ute</ForeName>
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<Affiliation>Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität, Dresden, Germany.</Affiliation>
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<LastName>Lopez-Jaramillo</LastName>
<ForeName>Carlos</ForeName>
<Initials>C</Initials>
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<Affiliation>Mood Disorders Program, Fundacion San Vicente de Paul, Department of Psychiatry, Universidad de Antioquia, Medellín, Colombia.</Affiliation>
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<LastName>MacQueen</LastName>
<ForeName>Glenda</ForeName>
<Initials>G</Initials>
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<ForeName>Mirko</ForeName>
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<ForeName>Mónica</ForeName>
<Initials>M</Initials>
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<Affiliation>Department of Psychiatry, University Hospital of Alava, University of the Basque Country, CIBERSAM, Vitoria, Spain.</Affiliation>
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<LastName>Melle</LastName>
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<LastName>Monteith</LastName>
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<Affiliation>Michigan State University College of Human Medicine, Traverse City Campus, Traverse City, MI, USA.</Affiliation>
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<LastName>Morken</LastName>
<ForeName>Gunnar</ForeName>
<Initials>G</Initials>
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<LastName>Munoz</LastName>
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<Affiliation>Department of Psychiatry, University of California San Diego, San Diego, CA, USA.</Affiliation>
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<LastName>Nery</LastName>
<ForeName>Fabiano G</ForeName>
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<Affiliation>Bipolar Disorder Research Program, Department of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil.</Affiliation>
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<LastName>O'Donovan</LastName>
<ForeName>Claire</ForeName>
<Initials>C</Initials>
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<Affiliation>Department of Psychiatry, Dalhousie University, Halifax, NS, Canada.</Affiliation>
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<LastName>Osher</LastName>
<ForeName>Yamima</ForeName>
<Initials>Y</Initials>
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<Affiliation>Department of Psychiatry, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva Mental Health Center, Beer Sheva, Israel.</Affiliation>
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<LastName>Pfennig</LastName>
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<name sortKey="Stein, Dan J" sort="Stein, Dan J" uniqKey="Stein D" first="Dan J" last="Stein">Dan J. Stein</name>
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