Contemporary challenges of catheter ablation for atrial fibrillation.
Identifieur interne : 001D72 ( Ncbi/Merge ); précédent : 001D71; suivant : 001D73Contemporary challenges of catheter ablation for atrial fibrillation.
Auteurs : Rukshen Weerasooriya [Australie] ; Ashok J. Shah [France] ; Meleze Hocini [France] ; Pierre Jaïs [France] ; Michel Haïssaguerre [France]Source :
- Clinical therapeutics [ 1879-114X ] ; 2014.
Descripteurs français
- KwdFr :
- MESH :
- analyse : Adénosine.
- anatomopathologie : Atrium du coeur.
- physiopathologie : Fibrillation auriculaire.
- Ablation par cathéter, Fibrillation auriculaire, Fibrose, Humains, Résultat thérapeutique, Sélection de patients, Techniques électrophysiologiques cardiaques, Veines pulmonaires.
English descriptors
- KwdEn :
- MESH :
- chemical , analysis : Adenosine.
- methods : Catheter Ablation.
- pathology : Heart Atria.
- physiopathology : Atrial Fibrillation.
- surgery : Atrial Fibrillation.
- Electrophysiologic Techniques, Cardiac, Fibrosis, Humans, Patient Selection, Pulmonary Veins, Treatment Outcome.
Abstract
Catheter ablation of atrial fibrillation (AF) is now one of the most frequently performed ablation procedures, but there are currently 2 important challenges: achieving permanent/durable rather than transient pulmonary vein isolation (PVI) and improving the results of ablation for the wider patient population with persistent AF.
DOI: 10.1016/j.clinthera.2014.07.014
PubMed: 25189853
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pubmed:25189853Le document en format XML
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<term>Atrial Fibrillation (physiopathology)</term>
<term>Atrial Fibrillation (surgery)</term>
<term>Catheter Ablation (methods)</term>
<term>Electrophysiologic Techniques, Cardiac</term>
<term>Fibrosis</term>
<term>Heart Atria (pathology)</term>
<term>Humans</term>
<term>Patient Selection</term>
<term>Pulmonary Veins</term>
<term>Treatment Outcome</term>
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<term>Adénosine (analyse)</term>
<term>Atrium du coeur (anatomopathologie)</term>
<term>Fibrillation auriculaire ()</term>
<term>Fibrillation auriculaire (physiopathologie)</term>
<term>Fibrose</term>
<term>Humains</term>
<term>Résultat thérapeutique</term>
<term>Sélection de patients</term>
<term>Techniques électrophysiologiques cardiaques</term>
<term>Veines pulmonaires</term>
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<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Catheter Ablation</term>
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<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Heart Atria</term>
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</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Atrial Fibrillation</term>
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<term>Humans</term>
<term>Patient Selection</term>
<term>Pulmonary Veins</term>
<term>Treatment Outcome</term>
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<term>Fibrillation auriculaire</term>
<term>Fibrose</term>
<term>Humains</term>
<term>Résultat thérapeutique</term>
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<front><div type="abstract" xml:lang="en">Catheter ablation of atrial fibrillation (AF) is now one of the most frequently performed ablation procedures, but there are currently 2 important challenges: achieving permanent/durable rather than transient pulmonary vein isolation (PVI) and improving the results of ablation for the wider patient population with persistent AF.</div>
</front>
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<DateCreated><Year>2014</Year>
<Month>09</Month>
<Day>19</Day>
</DateCreated>
<DateCompleted><Year>2016</Year>
<Month>03</Month>
<Day>29</Day>
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<Month>09</Month>
<Day>19</Day>
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<JournalIssue CitedMedium="Internet"><Volume>36</Volume>
<Issue>9</Issue>
<PubDate><Year>2014</Year>
<Month>Sep</Month>
<Day>01</Day>
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<Title>Clinical therapeutics</Title>
<ISOAbbreviation>Clin Ther</ISOAbbreviation>
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<ArticleTitle>Contemporary challenges of catheter ablation for atrial fibrillation.</ArticleTitle>
<Pagination><MedlinePgn>1145-50</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.clinthera.2014.07.014</ELocationID>
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<Abstract><AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">Catheter ablation of atrial fibrillation (AF) is now one of the most frequently performed ablation procedures, but there are currently 2 important challenges: achieving permanent/durable rather than transient pulmonary vein isolation (PVI) and improving the results of ablation for the wider patient population with persistent AF.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Recent technical advances in the technique of ablation and the results of clinical trials aimed at achieving more permanent and durable PVI are reviewed. We also summarize recent advances in identifying atrial fibrosis and in understanding the pathophysiology of AF relevant to selecting patients for ablation of persistent AF.</AbstractText>
<AbstractText Label="FINDINGS" NlmCategory="RESULTS">The use of contact force-sensing technology, adenosine testing after ablation, and pace capture-guided ablation all have the potential for achieving more durable ablation. Selection of patients suitable for ablation of persistent AF may be improved by assessing the extent of atrial fibrosis with delayed enhancement imaging with cardiac magnetic resonance or by assessing the pattern of atrial electrical activity with the use of complex atrial electrograms. Advances in treatment are likely to result from the recognition of localized rotors and focal sources as primary sustaining mechanisms for all types of human AF and in the use of noninvasive mapping for their identification. Linear ablation to supplement PVI may improve the results of AF ablation.</AbstractText>
<AbstractText Label="IMPLICATIONS" NlmCategory="CONCLUSIONS">Rapidly unfolding advances in the techniques of AF ablation and the understanding of mechanisms of AF hold promise for improving the durability of PVI and for extending the technique to carefully selected patients with persistent AF.</AbstractText>
<CopyrightInformation>Copyright © 2014 Elsevier HS Journals, Inc. All rights reserved.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Weerasooriya</LastName>
<ForeName>Rukshen</ForeName>
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<AffiliationInfo><Affiliation>University of Western Australia, Crawley, Royal Perth Hospital, Perth, Hollywood Private Hospital, Nedlands, Western Australia, Australia. Electronic address: rukshen@gmail.com.</Affiliation>
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<Author ValidYN="Y"><LastName>Shah</LastName>
<ForeName>Ashok J</ForeName>
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<AffiliationInfo><Affiliation>University of Bordeaux, Bordeaux, Hôpital Cardiologique du Haut-Leveque, Pessac, France.</Affiliation>
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<Author ValidYN="Y"><LastName>Jaïs</LastName>
<ForeName>Pierre</ForeName>
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