Ataluren treatment of patients with nonsense mutation dystrophinopathy
Identifieur interne : 001C39 ( Ncbi/Merge ); précédent : 001C38; suivant : 001C40Ataluren treatment of patients with nonsense mutation dystrophinopathy
Auteurs : Katharine Bushby [Royaume-Uni] ; Richard Finkel [États-Unis] ; Brenda Wong [États-Unis] ; Richard Barohn [États-Unis] ; Craig Campbell [Canada] ; Giacomo P. Comi [Italie] ; Anne M. Connolly [États-Unis] ; John W. Day [États-Unis] ; Kevin M. Flanigan [États-Unis] ; Nathalie Goemans [Belgique] ; Kristi J. Jones ; Eugenio Mercuri [Italie] ; Ros Quinlivan [Royaume-Uni] ; James B. Renfroe [États-Unis] ; Barry Russman [États-Unis] ; Monique M. Ryan [Australie] ; Mar Tulinius [Suède] ; Thomas Voit [France] ; Steven A. Moore [États-Unis] ; H. Lee Sweeney [États-Unis] ; Richard T. Abresch [États-Unis] ; Kim L. Coleman [États-Unis] ; Michelle Eagle [Royaume-Uni] ; Julaine Florence [États-Unis] ; Eduard Gappmaier [États-Unis] ; Allan M. Glanzman [États-Unis] ; Erik Henricson [États-Unis] ; Jay Barth [États-Unis] ; Gary L. Elfring [États-Unis] ; Allen Reha [États-Unis] ; Robert J. Spiegel [États-Unis] ; Michael W. O'Donnell [États-Unis] ; Stuart W. Peltz [États-Unis] ; Craig M. Mcdonald [États-Unis]Source :
- Muscle & Nerve [ 0148-639X ] ; 2014.
Abstract
Url:
DOI: 10.1002/mus.24332
PubMed: 25042182
PubMed Central: 4241581
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 002778
- to stream Pmc, to step Curation: 002628
- to stream Pmc, to step Checkpoint: 001737
Links to Exploration step
PMC:4241581Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Ataluren treatment of patients with nonsense mutation dystrophinopathy</title>
<author><name sortKey="Bushby, Katharine" sort="Bushby, Katharine" uniqKey="Bushby K" first="Katharine" last="Bushby">Katharine Bushby</name>
<affiliation wicri:level="1"><nlm:aff id="au1"><institution>Institute of Genetic Medicine, Newcastle University</institution>
<addr-line>Newcastle upon Tyne, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Newcastle upon Tyne</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Finkel, Richard" sort="Finkel, Richard" uniqKey="Finkel R" first="Richard" last="Finkel">Richard Finkel</name>
<affiliation wicri:level="1"><nlm:aff id="au2"><institution>The Children's Hospital of Philadelphia</institution>
<addr-line>Pennsylvania, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Pennsylvania</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wong, Brenda" sort="Wong, Brenda" uniqKey="Wong B" first="Brenda" last="Wong">Brenda Wong</name>
<affiliation wicri:level="1"><nlm:aff id="au3"><institution>Cincinnati Children's Hospital Medical Center</institution>
<addr-line>Ohio, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Ohio</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Barohn, Richard" sort="Barohn, Richard" uniqKey="Barohn R" first="Richard" last="Barohn">Richard Barohn</name>
<affiliation wicri:level="1"><nlm:aff id="au4"><institution>University of Kansas Medical Center</institution>
<addr-line>Kansas, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Kansas</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Campbell, Craig" sort="Campbell, Craig" uniqKey="Campbell C" first="Craig" last="Campbell">Craig Campbell</name>
<affiliation wicri:level="1"><nlm:aff id="au5"><institution>University of Western Ontario</institution>
<addr-line>London, Ontario, Canada</addr-line>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>London, Ontario</wicri:regionArea>
<wicri:noRegion>Ontario</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Comi, Giacomo P" sort="Comi, Giacomo P" uniqKey="Comi G" first="Giacomo P" last="Comi">Giacomo P. Comi</name>
<affiliation wicri:level="3"><nlm:aff id="au6"><institution>Dino Ferrari Centre, Department of Neurological Sciences, University of Milan</institution>
<addr-line>I.R.C.C.S. Foundation Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy</addr-line>
</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>I.R.C.C.S. Foundation Ca' Granda, Ospedale Maggiore Policlinico, Milan</wicri:regionArea>
<placeName><settlement type="city">Milan</settlement>
<region nuts="2">Lombardie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Connolly, Anne M" sort="Connolly, Anne M" uniqKey="Connolly A" first="Anne M" last="Connolly">Anne M. Connolly</name>
<affiliation wicri:level="1"><nlm:aff id="au7"><institution>Washington University School of Medicine at St. Louis</institution>
<addr-line>Missouri, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Missouri</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Day, John W" sort="Day, John W" uniqKey="Day J" first="John W" last="Day">John W. Day</name>
<affiliation wicri:level="2"><nlm:aff id="au8"><institution>University of Minnesota</institution>
<addr-line>Minneapolis, Minnesota, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Minneapolis, Minnesota</wicri:regionArea>
<placeName><region type="state">Minnesota</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Flanigan, Kevin M" sort="Flanigan, Kevin M" uniqKey="Flanigan K" first="Kevin M" last="Flanigan">Kevin M. Flanigan</name>
<affiliation wicri:level="2"><nlm:aff id="au9"><institution>Nationwide Children's Hospital and the Ohio State University</institution>
<addr-line>Columbus, Ohio, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Columbus, Ohio</wicri:regionArea>
<placeName><region type="state">Ohio</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Goemans, Nathalie" sort="Goemans, Nathalie" uniqKey="Goemans N" first="Nathalie" last="Goemans">Nathalie Goemans</name>
<affiliation wicri:level="1"><nlm:aff id="au10"><institution>University Hospitals Leuven</institution>
<addr-line>Leuven, Belgium</addr-line>
</nlm:aff>
<country xml:lang="fr">Belgique</country>
<wicri:regionArea>Leuven</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Jones, Kristi J" sort="Jones, Kristi J" uniqKey="Jones K" first="Kristi J" last="Jones">Kristi J. Jones</name>
<affiliation><nlm:aff id="au11"><institution>Department of Clinical Genetics, Sydney Children's Hospital Network, and Disciplines of Genetics and Paediatrics and Child Health, Faculty of Medicine University of Sydney</institution>
<addr-line>Australia</addr-line>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Mercuri, Eugenio" sort="Mercuri, Eugenio" uniqKey="Mercuri E" first="Eugenio" last="Mercuri">Eugenio Mercuri</name>
<affiliation wicri:level="1"><nlm:aff id="au12"><institution>Pediatric Neurology Unit, Polilcinico Gemelli, Università Cattolica Sacro Cuore</institution>
<addr-line>Rome, Italy</addr-line>
</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Rome</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Quinlivan, Ros" sort="Quinlivan, Ros" uniqKey="Quinlivan R" first="Ros" last="Quinlivan">Ros Quinlivan</name>
<affiliation wicri:level="1"><nlm:aff id="au13"><institution>The Institute of Neurology</institution>
<addr-line>London, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>London</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Renfroe, James B" sort="Renfroe, James B" uniqKey="Renfroe J" first="James B" last="Renfroe">James B. Renfroe</name>
<affiliation wicri:level="1"><nlm:aff id="au14"><institution>Northwest Florida Clinical Research Group</institution>
<addr-line>Florida, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Florida</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Russman, Barry" sort="Russman, Barry" uniqKey="Russman B" first="Barry" last="Russman">Barry Russman</name>
<affiliation wicri:level="1"><nlm:aff id="au15"><institution>Oregon Health & Science University and Shriners Hospital for Children</institution>
<addr-line>Oregon, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Oregon</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ryan, Monique M" sort="Ryan, Monique M" uniqKey="Ryan M" first="Monique M" last="Ryan">Monique M. Ryan</name>
<affiliation wicri:level="1"><nlm:aff id="au16"><institution>Royal Children's Hospital, Murdoch Childrens Research Institute and University of Melbourne</institution>
<addr-line>Parkville, Victoria, Australia</addr-line>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Parkville, Victoria</wicri:regionArea>
<wicri:noRegion>Victoria</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Tulinius, Mar" sort="Tulinius, Mar" uniqKey="Tulinius M" first="Mar" last="Tulinius">Mar Tulinius</name>
<affiliation wicri:level="1"><nlm:aff id="au17"><institution>Department of Pediatrics, The University of Gothenburg</institution>
<addr-line>Gothenburg, Sweden</addr-line>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Gothenburg</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Voit, Thomas" sort="Voit, Thomas" uniqKey="Voit T" first="Thomas" last="Voit">Thomas Voit</name>
<affiliation wicri:level="3"><nlm:aff id="au18"><institution>Institut de Myologie, University Pierre et Marie Curie Paris 6</institution>
<addr-line>UM 76, INSERM U 974, CNRS UMR 7215, Paris, France</addr-line>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>UM 76, INSERM U 974, CNRS UMR 7215, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Moore, Steven A" sort="Moore, Steven A" uniqKey="Moore S" first="Steven A" last="Moore">Steven A. Moore</name>
<affiliation wicri:level="1"><nlm:aff id="au19"><institution>University of Iowa</institution>
<addr-line>Iowa, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Iowa</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lee Sweeney, H" sort="Lee Sweeney, H" uniqKey="Lee Sweeney H" first="H" last="Lee Sweeney">H. Lee Sweeney</name>
<affiliation wicri:level="1"><nlm:aff id="au20"><institution>University of Pennsylvania</institution>
<addr-line>Pennsylvania, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Pennsylvania</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Abresch, Richard T" sort="Abresch, Richard T" uniqKey="Abresch R" first="Richard T" last="Abresch">Richard T. Abresch</name>
<affiliation wicri:level="1"><nlm:aff id="au21"><institution>UC Davis Children's Hospital, Lawrence J. Ellison Ambulatory Care Center, Physical Medicine & Rehabilitation</institution>
<addr-line>4860 Y St., Suite 1700, Sacramento, California, 95817, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>4860 Y St., Suite 1700, Sacramento, California, 95817</wicri:regionArea>
<wicri:noRegion>95817</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Coleman, Kim L" sort="Coleman, Kim L" uniqKey="Coleman K" first="Kim L" last="Coleman">Kim L. Coleman</name>
<affiliation wicri:level="2"><nlm:aff id="au22"><institution>OrthoCare Innovations</institution>
<addr-line>Mountlake Terrace, Washington, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Mountlake Terrace, Washington</wicri:regionArea>
<placeName><region type="state">Washington (État)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Eagle, Michelle" sort="Eagle, Michelle" uniqKey="Eagle M" first="Michelle" last="Eagle">Michelle Eagle</name>
<affiliation wicri:level="1"><nlm:aff id="au1"><institution>Institute of Genetic Medicine, Newcastle University</institution>
<addr-line>Newcastle upon Tyne, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Newcastle upon Tyne</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Florence, Julaine" sort="Florence, Julaine" uniqKey="Florence J" first="Julaine" last="Florence">Julaine Florence</name>
<affiliation wicri:level="1"><nlm:aff id="au7"><institution>Washington University School of Medicine at St. Louis</institution>
<addr-line>Missouri, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Missouri</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gappmaier, Eduard" sort="Gappmaier, Eduard" uniqKey="Gappmaier E" first="Eduard" last="Gappmaier">Eduard Gappmaier</name>
<affiliation wicri:level="2"><nlm:aff id="au23"><institution>University of Utah School of Medicine</institution>
<addr-line>Salt Lake City, Utah, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Salt Lake City, Utah</wicri:regionArea>
<placeName><region type="state">Utah</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Glanzman, Allan M" sort="Glanzman, Allan M" uniqKey="Glanzman A" first="Allan M" last="Glanzman">Allan M. Glanzman</name>
<affiliation wicri:level="1"><nlm:aff id="au2"><institution>The Children's Hospital of Philadelphia</institution>
<addr-line>Pennsylvania, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Pennsylvania</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Henricson, Erik" sort="Henricson, Erik" uniqKey="Henricson E" first="Erik" last="Henricson">Erik Henricson</name>
<affiliation wicri:level="1"><nlm:aff id="au21"><institution>UC Davis Children's Hospital, Lawrence J. Ellison Ambulatory Care Center, Physical Medicine & Rehabilitation</institution>
<addr-line>4860 Y St., Suite 1700, Sacramento, California, 95817, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>4860 Y St., Suite 1700, Sacramento, California, 95817</wicri:regionArea>
<wicri:noRegion>95817</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Barth, Jay" sort="Barth, Jay" uniqKey="Barth J" first="Jay" last="Barth">Jay Barth</name>
<affiliation wicri:level="2"><nlm:aff id="au24"><institution>PTC Therapeutics</institution>
<addr-line>South Plainfield, New Jersey, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>South Plainfield, New Jersey</wicri:regionArea>
<placeName><region type="state">New Jersey</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Elfring, Gary L" sort="Elfring, Gary L" uniqKey="Elfring G" first="Gary L" last="Elfring">Gary L. Elfring</name>
<affiliation wicri:level="2"><nlm:aff id="au24"><institution>PTC Therapeutics</institution>
<addr-line>South Plainfield, New Jersey, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>South Plainfield, New Jersey</wicri:regionArea>
<placeName><region type="state">New Jersey</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Reha, Allen" sort="Reha, Allen" uniqKey="Reha A" first="Allen" last="Reha">Allen Reha</name>
<affiliation wicri:level="2"><nlm:aff id="au24"><institution>PTC Therapeutics</institution>
<addr-line>South Plainfield, New Jersey, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>South Plainfield, New Jersey</wicri:regionArea>
<placeName><region type="state">New Jersey</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Spiegel, Robert J" sort="Spiegel, Robert J" uniqKey="Spiegel R" first="Robert J" last="Spiegel">Robert J. Spiegel</name>
<affiliation wicri:level="2"><nlm:aff id="au24"><institution>PTC Therapeutics</institution>
<addr-line>South Plainfield, New Jersey, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>South Plainfield, New Jersey</wicri:regionArea>
<placeName><region type="state">New Jersey</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="O Donnell, Michael W" sort="O Donnell, Michael W" uniqKey="O Donnell M" first="Michael W" last="O'Donnell">Michael W. O'Donnell</name>
<affiliation wicri:level="2"><nlm:aff id="au24"><institution>PTC Therapeutics</institution>
<addr-line>South Plainfield, New Jersey, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>South Plainfield, New Jersey</wicri:regionArea>
<placeName><region type="state">New Jersey</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Peltz, Stuart W" sort="Peltz, Stuart W" uniqKey="Peltz S" first="Stuart W" last="Peltz">Stuart W. Peltz</name>
<affiliation wicri:level="2"><nlm:aff id="au24"><institution>PTC Therapeutics</institution>
<addr-line>South Plainfield, New Jersey, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>South Plainfield, New Jersey</wicri:regionArea>
<placeName><region type="state">New Jersey</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mcdonald, Craig M" sort="Mcdonald, Craig M" uniqKey="Mcdonald C" first="Craig M" last="Mcdonald">Craig M. Mcdonald</name>
<affiliation wicri:level="1"><nlm:aff id="au21"><institution>UC Davis Children's Hospital, Lawrence J. Ellison Ambulatory Care Center, Physical Medicine & Rehabilitation</institution>
<addr-line>4860 Y St., Suite 1700, Sacramento, California, 95817, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>4860 Y St., Suite 1700, Sacramento, California, 95817</wicri:regionArea>
<wicri:noRegion>95817</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">25042182</idno>
<idno type="pmc">4241581</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241581</idno>
<idno type="RBID">PMC:4241581</idno>
<idno type="doi">10.1002/mus.24332</idno>
<date when="2014">2014</date>
<idno type="wicri:Area/Pmc/Corpus">002778</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002778</idno>
<idno type="wicri:Area/Pmc/Curation">002628</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002628</idno>
<idno type="wicri:Area/Pmc/Checkpoint">001737</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001737</idno>
<idno type="wicri:Area/Ncbi/Merge">001C39</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Ataluren treatment of patients with nonsense mutation dystrophinopathy</title>
<author><name sortKey="Bushby, Katharine" sort="Bushby, Katharine" uniqKey="Bushby K" first="Katharine" last="Bushby">Katharine Bushby</name>
<affiliation wicri:level="1"><nlm:aff id="au1"><institution>Institute of Genetic Medicine, Newcastle University</institution>
<addr-line>Newcastle upon Tyne, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Newcastle upon Tyne</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Finkel, Richard" sort="Finkel, Richard" uniqKey="Finkel R" first="Richard" last="Finkel">Richard Finkel</name>
<affiliation wicri:level="1"><nlm:aff id="au2"><institution>The Children's Hospital of Philadelphia</institution>
<addr-line>Pennsylvania, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Pennsylvania</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wong, Brenda" sort="Wong, Brenda" uniqKey="Wong B" first="Brenda" last="Wong">Brenda Wong</name>
<affiliation wicri:level="1"><nlm:aff id="au3"><institution>Cincinnati Children's Hospital Medical Center</institution>
<addr-line>Ohio, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Ohio</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Barohn, Richard" sort="Barohn, Richard" uniqKey="Barohn R" first="Richard" last="Barohn">Richard Barohn</name>
<affiliation wicri:level="1"><nlm:aff id="au4"><institution>University of Kansas Medical Center</institution>
<addr-line>Kansas, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Kansas</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Campbell, Craig" sort="Campbell, Craig" uniqKey="Campbell C" first="Craig" last="Campbell">Craig Campbell</name>
<affiliation wicri:level="1"><nlm:aff id="au5"><institution>University of Western Ontario</institution>
<addr-line>London, Ontario, Canada</addr-line>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>London, Ontario</wicri:regionArea>
<wicri:noRegion>Ontario</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Comi, Giacomo P" sort="Comi, Giacomo P" uniqKey="Comi G" first="Giacomo P" last="Comi">Giacomo P. Comi</name>
<affiliation wicri:level="3"><nlm:aff id="au6"><institution>Dino Ferrari Centre, Department of Neurological Sciences, University of Milan</institution>
<addr-line>I.R.C.C.S. Foundation Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy</addr-line>
</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>I.R.C.C.S. Foundation Ca' Granda, Ospedale Maggiore Policlinico, Milan</wicri:regionArea>
<placeName><settlement type="city">Milan</settlement>
<region nuts="2">Lombardie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Connolly, Anne M" sort="Connolly, Anne M" uniqKey="Connolly A" first="Anne M" last="Connolly">Anne M. Connolly</name>
<affiliation wicri:level="1"><nlm:aff id="au7"><institution>Washington University School of Medicine at St. Louis</institution>
<addr-line>Missouri, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Missouri</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Day, John W" sort="Day, John W" uniqKey="Day J" first="John W" last="Day">John W. Day</name>
<affiliation wicri:level="2"><nlm:aff id="au8"><institution>University of Minnesota</institution>
<addr-line>Minneapolis, Minnesota, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Minneapolis, Minnesota</wicri:regionArea>
<placeName><region type="state">Minnesota</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Flanigan, Kevin M" sort="Flanigan, Kevin M" uniqKey="Flanigan K" first="Kevin M" last="Flanigan">Kevin M. Flanigan</name>
<affiliation wicri:level="2"><nlm:aff id="au9"><institution>Nationwide Children's Hospital and the Ohio State University</institution>
<addr-line>Columbus, Ohio, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Columbus, Ohio</wicri:regionArea>
<placeName><region type="state">Ohio</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Goemans, Nathalie" sort="Goemans, Nathalie" uniqKey="Goemans N" first="Nathalie" last="Goemans">Nathalie Goemans</name>
<affiliation wicri:level="1"><nlm:aff id="au10"><institution>University Hospitals Leuven</institution>
<addr-line>Leuven, Belgium</addr-line>
</nlm:aff>
<country xml:lang="fr">Belgique</country>
<wicri:regionArea>Leuven</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Jones, Kristi J" sort="Jones, Kristi J" uniqKey="Jones K" first="Kristi J" last="Jones">Kristi J. Jones</name>
<affiliation><nlm:aff id="au11"><institution>Department of Clinical Genetics, Sydney Children's Hospital Network, and Disciplines of Genetics and Paediatrics and Child Health, Faculty of Medicine University of Sydney</institution>
<addr-line>Australia</addr-line>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Mercuri, Eugenio" sort="Mercuri, Eugenio" uniqKey="Mercuri E" first="Eugenio" last="Mercuri">Eugenio Mercuri</name>
<affiliation wicri:level="1"><nlm:aff id="au12"><institution>Pediatric Neurology Unit, Polilcinico Gemelli, Università Cattolica Sacro Cuore</institution>
<addr-line>Rome, Italy</addr-line>
</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Rome</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Quinlivan, Ros" sort="Quinlivan, Ros" uniqKey="Quinlivan R" first="Ros" last="Quinlivan">Ros Quinlivan</name>
<affiliation wicri:level="1"><nlm:aff id="au13"><institution>The Institute of Neurology</institution>
<addr-line>London, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>London</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Renfroe, James B" sort="Renfroe, James B" uniqKey="Renfroe J" first="James B" last="Renfroe">James B. Renfroe</name>
<affiliation wicri:level="1"><nlm:aff id="au14"><institution>Northwest Florida Clinical Research Group</institution>
<addr-line>Florida, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Florida</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Russman, Barry" sort="Russman, Barry" uniqKey="Russman B" first="Barry" last="Russman">Barry Russman</name>
<affiliation wicri:level="1"><nlm:aff id="au15"><institution>Oregon Health & Science University and Shriners Hospital for Children</institution>
<addr-line>Oregon, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Oregon</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ryan, Monique M" sort="Ryan, Monique M" uniqKey="Ryan M" first="Monique M" last="Ryan">Monique M. Ryan</name>
<affiliation wicri:level="1"><nlm:aff id="au16"><institution>Royal Children's Hospital, Murdoch Childrens Research Institute and University of Melbourne</institution>
<addr-line>Parkville, Victoria, Australia</addr-line>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Parkville, Victoria</wicri:regionArea>
<wicri:noRegion>Victoria</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Tulinius, Mar" sort="Tulinius, Mar" uniqKey="Tulinius M" first="Mar" last="Tulinius">Mar Tulinius</name>
<affiliation wicri:level="1"><nlm:aff id="au17"><institution>Department of Pediatrics, The University of Gothenburg</institution>
<addr-line>Gothenburg, Sweden</addr-line>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Gothenburg</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Voit, Thomas" sort="Voit, Thomas" uniqKey="Voit T" first="Thomas" last="Voit">Thomas Voit</name>
<affiliation wicri:level="3"><nlm:aff id="au18"><institution>Institut de Myologie, University Pierre et Marie Curie Paris 6</institution>
<addr-line>UM 76, INSERM U 974, CNRS UMR 7215, Paris, France</addr-line>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>UM 76, INSERM U 974, CNRS UMR 7215, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Moore, Steven A" sort="Moore, Steven A" uniqKey="Moore S" first="Steven A" last="Moore">Steven A. Moore</name>
<affiliation wicri:level="1"><nlm:aff id="au19"><institution>University of Iowa</institution>
<addr-line>Iowa, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Iowa</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lee Sweeney, H" sort="Lee Sweeney, H" uniqKey="Lee Sweeney H" first="H" last="Lee Sweeney">H. Lee Sweeney</name>
<affiliation wicri:level="1"><nlm:aff id="au20"><institution>University of Pennsylvania</institution>
<addr-line>Pennsylvania, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Pennsylvania</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Abresch, Richard T" sort="Abresch, Richard T" uniqKey="Abresch R" first="Richard T" last="Abresch">Richard T. Abresch</name>
<affiliation wicri:level="1"><nlm:aff id="au21"><institution>UC Davis Children's Hospital, Lawrence J. Ellison Ambulatory Care Center, Physical Medicine & Rehabilitation</institution>
<addr-line>4860 Y St., Suite 1700, Sacramento, California, 95817, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>4860 Y St., Suite 1700, Sacramento, California, 95817</wicri:regionArea>
<wicri:noRegion>95817</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Coleman, Kim L" sort="Coleman, Kim L" uniqKey="Coleman K" first="Kim L" last="Coleman">Kim L. Coleman</name>
<affiliation wicri:level="2"><nlm:aff id="au22"><institution>OrthoCare Innovations</institution>
<addr-line>Mountlake Terrace, Washington, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Mountlake Terrace, Washington</wicri:regionArea>
<placeName><region type="state">Washington (État)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Eagle, Michelle" sort="Eagle, Michelle" uniqKey="Eagle M" first="Michelle" last="Eagle">Michelle Eagle</name>
<affiliation wicri:level="1"><nlm:aff id="au1"><institution>Institute of Genetic Medicine, Newcastle University</institution>
<addr-line>Newcastle upon Tyne, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Newcastle upon Tyne</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Florence, Julaine" sort="Florence, Julaine" uniqKey="Florence J" first="Julaine" last="Florence">Julaine Florence</name>
<affiliation wicri:level="1"><nlm:aff id="au7"><institution>Washington University School of Medicine at St. Louis</institution>
<addr-line>Missouri, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Missouri</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gappmaier, Eduard" sort="Gappmaier, Eduard" uniqKey="Gappmaier E" first="Eduard" last="Gappmaier">Eduard Gappmaier</name>
<affiliation wicri:level="2"><nlm:aff id="au23"><institution>University of Utah School of Medicine</institution>
<addr-line>Salt Lake City, Utah, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Salt Lake City, Utah</wicri:regionArea>
<placeName><region type="state">Utah</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Glanzman, Allan M" sort="Glanzman, Allan M" uniqKey="Glanzman A" first="Allan M" last="Glanzman">Allan M. Glanzman</name>
<affiliation wicri:level="1"><nlm:aff id="au2"><institution>The Children's Hospital of Philadelphia</institution>
<addr-line>Pennsylvania, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Pennsylvania</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Henricson, Erik" sort="Henricson, Erik" uniqKey="Henricson E" first="Erik" last="Henricson">Erik Henricson</name>
<affiliation wicri:level="1"><nlm:aff id="au21"><institution>UC Davis Children's Hospital, Lawrence J. Ellison Ambulatory Care Center, Physical Medicine & Rehabilitation</institution>
<addr-line>4860 Y St., Suite 1700, Sacramento, California, 95817, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>4860 Y St., Suite 1700, Sacramento, California, 95817</wicri:regionArea>
<wicri:noRegion>95817</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Barth, Jay" sort="Barth, Jay" uniqKey="Barth J" first="Jay" last="Barth">Jay Barth</name>
<affiliation wicri:level="2"><nlm:aff id="au24"><institution>PTC Therapeutics</institution>
<addr-line>South Plainfield, New Jersey, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>South Plainfield, New Jersey</wicri:regionArea>
<placeName><region type="state">New Jersey</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Elfring, Gary L" sort="Elfring, Gary L" uniqKey="Elfring G" first="Gary L" last="Elfring">Gary L. Elfring</name>
<affiliation wicri:level="2"><nlm:aff id="au24"><institution>PTC Therapeutics</institution>
<addr-line>South Plainfield, New Jersey, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>South Plainfield, New Jersey</wicri:regionArea>
<placeName><region type="state">New Jersey</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Reha, Allen" sort="Reha, Allen" uniqKey="Reha A" first="Allen" last="Reha">Allen Reha</name>
<affiliation wicri:level="2"><nlm:aff id="au24"><institution>PTC Therapeutics</institution>
<addr-line>South Plainfield, New Jersey, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>South Plainfield, New Jersey</wicri:regionArea>
<placeName><region type="state">New Jersey</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Spiegel, Robert J" sort="Spiegel, Robert J" uniqKey="Spiegel R" first="Robert J" last="Spiegel">Robert J. Spiegel</name>
<affiliation wicri:level="2"><nlm:aff id="au24"><institution>PTC Therapeutics</institution>
<addr-line>South Plainfield, New Jersey, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>South Plainfield, New Jersey</wicri:regionArea>
<placeName><region type="state">New Jersey</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="O Donnell, Michael W" sort="O Donnell, Michael W" uniqKey="O Donnell M" first="Michael W" last="O'Donnell">Michael W. O'Donnell</name>
<affiliation wicri:level="2"><nlm:aff id="au24"><institution>PTC Therapeutics</institution>
<addr-line>South Plainfield, New Jersey, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>South Plainfield, New Jersey</wicri:regionArea>
<placeName><region type="state">New Jersey</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Peltz, Stuart W" sort="Peltz, Stuart W" uniqKey="Peltz S" first="Stuart W" last="Peltz">Stuart W. Peltz</name>
<affiliation wicri:level="2"><nlm:aff id="au24"><institution>PTC Therapeutics</institution>
<addr-line>South Plainfield, New Jersey, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>South Plainfield, New Jersey</wicri:regionArea>
<placeName><region type="state">New Jersey</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mcdonald, Craig M" sort="Mcdonald, Craig M" uniqKey="Mcdonald C" first="Craig M" last="Mcdonald">Craig M. Mcdonald</name>
<affiliation wicri:level="1"><nlm:aff id="au21"><institution>UC Davis Children's Hospital, Lawrence J. Ellison Ambulatory Care Center, Physical Medicine & Rehabilitation</institution>
<addr-line>4860 Y St., Suite 1700, Sacramento, California, 95817, USA</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>4860 Y St., Suite 1700, Sacramento, California, 95817</wicri:regionArea>
<wicri:noRegion>95817</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">Muscle & Nerve</title>
<idno type="ISSN">0148-639X</idno>
<idno type="eISSN">1097-4598</idno>
<imprint><date when="2014">2014</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p><italic>Introduction</italic>
: Dystrophinopathy is a rare, severe muscle disorder, and nonsense mutations are found in 13% of cases. Ataluren was developed to enable ribosomal readthrough of premature stop codons in nonsense mutation (nm) genetic disorders. <italic>Methods</italic>
: Randomized, double-blind, placebo-controlled study; males ≥5 years with nm-dystrophinopathy received study drug orally 3 times daily, ataluren 10, 10, 20 mg/kg (<italic>N</italic>
= 57); ataluren 20, 20, 40 mg/kg (<italic>N</italic>
= 60); or placebo (<italic>N</italic>
= 57) for 48 weeks. The primary endpoint was change in 6-Minute Walk Distance (6MWD) at Week 48. <italic>Results</italic>
: Ataluren was generally well tolerated. The primary endpoint favored ataluren 10, 10, 20 mg/kg versus placebo; the week 48 6MWD Δ = 31.3 meters, <italic>post hoc P</italic>
= 0.056. Secondary endpoints (timed function tests) showed meaningful differences between ataluren 10, 10, 20 mg/kg, and placebo. <italic>Conclusions</italic>
: As the first investigational new drug targeting the underlying cause of nm-dystrophinopathy, ataluren offers promise as a treatment for this orphan genetic disorder with high unmet medical need. <italic>Muscle Nerve</italic>
<bold>50</bold>
: 477–487, 2014</p>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Dent, Km" uniqKey="Dent K">KM Dent</name>
</author>
<author><name sortKey="Dunn, Dm" uniqKey="Dunn D">DM Dunn</name>
</author>
<author><name sortKey="Von Niederhausern, Ac" uniqKey="Von Niederhausern A">AC von Niederhausern</name>
</author>
<author><name sortKey="Aoyagi, At" uniqKey="Aoyagi A">AT Aoyagi</name>
</author>
<author><name sortKey="Kerr, L" uniqKey="Kerr L">L Kerr</name>
</author>
<author><name sortKey="Bromberg, Mb" uniqKey="Bromberg M">MB Bromberg</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Welch, Em" uniqKey="Welch E">EM Welch</name>
</author>
<author><name sortKey="Barton, Er" uniqKey="Barton E">ER Barton</name>
</author>
<author><name sortKey="Zhuo, J" uniqKey="Zhuo J">J Zhuo</name>
</author>
<author><name sortKey="Tomizawa, Y" uniqKey="Tomizawa Y">Y Tomizawa</name>
</author>
<author><name sortKey="Friesen, Wj" uniqKey="Friesen W">WJ Friesen</name>
</author>
<author><name sortKey="Trifillis, P" uniqKey="Trifillis P">P Trifillis</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Du, M" uniqKey="Du M">M Du</name>
</author>
<author><name sortKey="Liu, X" uniqKey="Liu X">X Liu</name>
</author>
<author><name sortKey="Welch, Em" uniqKey="Welch E">EM Welch</name>
</author>
<author><name sortKey="Hirawat, S" uniqKey="Hirawat S">S Hirawat</name>
</author>
<author><name sortKey="Peltz, Sw" uniqKey="Peltz S">SW Peltz</name>
</author>
<author><name sortKey="Bedwell, Dm" uniqKey="Bedwell D">DM Bedwell</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wang, D" uniqKey="Wang D">D Wang</name>
</author>
<author><name sortKey="Shukla, C" uniqKey="Shukla C">C Shukla</name>
</author>
<author><name sortKey="Liu, X" uniqKey="Liu X">X Liu</name>
</author>
<author><name sortKey="Schoeb, Tr" uniqKey="Schoeb T">TR Schoeb</name>
</author>
<author><name sortKey="Clarke, La" uniqKey="Clarke L">LA Clarke</name>
</author>
<author><name sortKey="Bedwell, Dm" uniqKey="Bedwell D">DM Bedwell</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Malik, V" uniqKey="Malik V">V Malik</name>
</author>
<author><name sortKey="Rodino Klapac, Lr" uniqKey="Rodino Klapac L">LR Rodino-Klapac</name>
</author>
<author><name sortKey="Viollet, L" uniqKey="Viollet L">L Viollet</name>
</author>
<author><name sortKey="Wall, C" uniqKey="Wall C">C Wall</name>
</author>
<author><name sortKey="King, W" uniqKey="King W">W King</name>
</author>
<author><name sortKey="Al Dahhak, R" uniqKey="Al Dahhak R">R Al-Dahhak</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Goldmann, T" uniqKey="Goldmann T">T Goldmann</name>
</author>
<author><name sortKey="Overlack, N" uniqKey="Overlack N">N Overlack</name>
</author>
<author><name sortKey="Wolfrum, U" uniqKey="Wolfrum U">U Wolfrum</name>
</author>
<author><name sortKey="Nagel Wolfrum, K" uniqKey="Nagel Wolfrum K">K Nagel-Wolfrum</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sarkar, C" uniqKey="Sarkar C">C Sarkar</name>
</author>
<author><name sortKey="Zhang, Z" uniqKey="Zhang Z">Z Zhang</name>
</author>
<author><name sortKey="Mukherjee, Ab" uniqKey="Mukherjee A">AB Mukherjee</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Tan, L" uniqKey="Tan L">L Tan</name>
</author>
<author><name sortKey="Narayan, Sb" uniqKey="Narayan S">SB Narayan</name>
</author>
<author><name sortKey="Chen, J" uniqKey="Chen J">J Chen</name>
</author>
<author><name sortKey="Meyers, Gd" uniqKey="Meyers G">GD Meyers</name>
</author>
<author><name sortKey="Bennett, Mj" uniqKey="Bennett M">MJ Bennett</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Buck, Ne" uniqKey="Buck N">NE Buck</name>
</author>
<author><name sortKey="Wood, Lr" uniqKey="Wood L">LR Wood</name>
</author>
<author><name sortKey="Hamilton, Nj" uniqKey="Hamilton N">NJ Hamilton</name>
</author>
<author><name sortKey="Bennett, Mj" uniqKey="Bennett M">MJ Bennett</name>
</author>
<author><name sortKey="Peters, Hl" uniqKey="Peters H">HL Peters</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Gonzalez Hilarion, S" uniqKey="Gonzalez Hilarion S">S Gonzalez-Hilarion</name>
</author>
<author><name sortKey="Beghyn, T" uniqKey="Beghyn T">T Beghyn</name>
</author>
<author><name sortKey="Jia, J" uniqKey="Jia J">J Jia</name>
</author>
<author><name sortKey="Debreuck, N" uniqKey="Debreuck N">N Debreuck</name>
</author>
<author><name sortKey="Berte, G" uniqKey="Berte G">G Berte</name>
</author>
<author><name sortKey="Mamchaoui, K" uniqKey="Mamchaoui K">K Mamchaoui</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kayali, R" uniqKey="Kayali R">R Kayali</name>
</author>
<author><name sortKey="Ku, Jm" uniqKey="Ku J">JM Ku</name>
</author>
<author><name sortKey="Khitrov, G" uniqKey="Khitrov G">G Khitrov</name>
</author>
<author><name sortKey="Jung, Me" uniqKey="Jung M">ME Jung</name>
</author>
<author><name sortKey="Prikhodko, O" uniqKey="Prikhodko O">O Prikhodko</name>
</author>
<author><name sortKey="Bertoni, C" uniqKey="Bertoni C">C Bertoni</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sanchez Alcudia, R" uniqKey="Sanchez Alcudia R">R Sanchez-Alcudia</name>
</author>
<author><name sortKey="Perez, B" uniqKey="Perez B">B Perez</name>
</author>
<author><name sortKey="Ugarte, M" uniqKey="Ugarte M">M Ugarte</name>
</author>
<author><name sortKey="Desviat, Lr" uniqKey="Desviat L">LR Desviat</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Goldmann, T" uniqKey="Goldmann T">T Goldmann</name>
</author>
<author><name sortKey="Overlack, N" uniqKey="Overlack N">N Overlack</name>
</author>
<author><name sortKey="Moller, F" uniqKey="Moller F">F Möller</name>
</author>
<author><name sortKey="Belakhov, V" uniqKey="Belakhov V">V Belakhov</name>
</author>
<author><name sortKey="Van Wyk, M" uniqKey="Van Wyk M">M van Wyk</name>
</author>
<author><name sortKey="Baasov, T" uniqKey="Baasov T">T Baasov</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bartolomeo, R" uniqKey="Bartolomeo R">R Bartolomeo</name>
</author>
<author><name sortKey="Polishchuk, Ev" uniqKey="Polishchuk E">EV Polishchuk</name>
</author>
<author><name sortKey="Volpi, N" uniqKey="Volpi N">N Volpi</name>
</author>
<author><name sortKey="Polishchuk, Rs" uniqKey="Polishchuk R">RS Polishchuk</name>
</author>
<author><name sortKey="Auricchio, A" uniqKey="Auricchio A">A Auricchio</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Drake, Km" uniqKey="Drake K">KM Drake</name>
</author>
<author><name sortKey="Dunmore, Bj" uniqKey="Dunmore B">BJ Dunmore</name>
</author>
<author><name sortKey="Mcnelly, Ln" uniqKey="Mcnelly L">LN McNelly</name>
</author>
<author><name sortKey="Morrell, Nw" uniqKey="Morrell N">NW Morrell</name>
</author>
<author><name sortKey="Aldred, Ma" uniqKey="Aldred M">MA Aldred</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Du, L" uniqKey="Du L">L Du</name>
</author>
<author><name sortKey="Jung, Me" uniqKey="Jung M">ME Jung</name>
</author>
<author><name sortKey="Damoiseaux, R" uniqKey="Damoiseaux R">R Damoiseaux</name>
</author>
<author><name sortKey="Completo, G" uniqKey="Completo G">G Completo</name>
</author>
<author><name sortKey="Fike, F" uniqKey="Fike F">F Fike</name>
</author>
<author><name sortKey="Ku, Jm" uniqKey="Ku J">JM Ku</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Zhou, Y" uniqKey="Zhou Y">Y Zhou</name>
</author>
<author><name sortKey="Jiang, Q" uniqKey="Jiang Q">Q Jiang</name>
</author>
<author><name sortKey="Takahagi, S" uniqKey="Takahagi S">S Takahagi</name>
</author>
<author><name sortKey="Shao, C" uniqKey="Shao C">C Shao</name>
</author>
<author><name sortKey="Uitto, J" uniqKey="Uitto J">J Uitto</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Miller, Jn" uniqKey="Miller J">JN Miller</name>
</author>
<author><name sortKey="Chan, Ch" uniqKey="Chan C">CH Chan</name>
</author>
<author><name sortKey="Pearce, Da" uniqKey="Pearce D">DA Pearce</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Gregory Evans, Cy" uniqKey="Gregory Evans C">CY Gregory-Evans</name>
</author>
<author><name sortKey="Wang, X" uniqKey="Wang X">X Wang</name>
</author>
<author><name sortKey="Wasan, Km" uniqKey="Wasan K">KM Wasan</name>
</author>
<author><name sortKey="Zhao, J" uniqKey="Zhao J">J Zhao</name>
</author>
<author><name sortKey="Metcalfe, Al" uniqKey="Metcalfe A">AL Metcalfe</name>
</author>
<author><name sortKey="Gregory Evans, K" uniqKey="Gregory Evans K">K Gregory-Evans</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Yu, H" uniqKey="Yu H">H Yu</name>
</author>
<author><name sortKey="Liu, X" uniqKey="Liu X">X Liu</name>
</author>
<author><name sortKey="Huang, J" uniqKey="Huang J">J Huang</name>
</author>
<author><name sortKey="Zhang, Y" uniqKey="Zhang Y">Y Zhang</name>
</author>
<author><name sortKey="Hu, R" uniqKey="Hu R">R Hu</name>
</author>
<author><name sortKey="Pu, J" uniqKey="Pu J">J Pu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lojewski, X" uniqKey="Lojewski X">X Lojewski</name>
</author>
<author><name sortKey="Staropoli, Jf" uniqKey="Staropoli J">JF Staropoli</name>
</author>
<author><name sortKey="Biswas Legrand, S" uniqKey="Biswas Legrand S">S Biswas-Legrand</name>
</author>
<author><name sortKey="Simas, Am" uniqKey="Simas A">AM Simas</name>
</author>
<author><name sortKey="Haliw, L" uniqKey="Haliw L">L Haliw</name>
</author>
<author><name sortKey="Selig, Mk" uniqKey="Selig M">MK Selig</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Finkel, R" uniqKey="Finkel R">R Finkel</name>
</author>
<author><name sortKey="Flanigan, K" uniqKey="Flanigan K">K Flanigan</name>
</author>
<author><name sortKey="Wong, B" uniqKey="Wong B">B Wong</name>
</author>
<author><name sortKey="Bonnemann, C" uniqKey="Bonnemann C">C Bönnemann</name>
</author>
<author><name sortKey="Sampson, J" uniqKey="Sampson J">J Sampson</name>
</author>
<author><name sortKey="Sweeney, Hl" uniqKey="Sweeney H">HL Sweeney</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kerem, E" uniqKey="Kerem E">E Kerem</name>
</author>
<author><name sortKey="Hirawat, S" uniqKey="Hirawat S">S Hirawat</name>
</author>
<author><name sortKey="Armoni, S" uniqKey="Armoni S">S Armoni</name>
</author>
<author><name sortKey="Yaakov, Y" uniqKey="Yaakov Y">Y Yaakov</name>
</author>
<author><name sortKey="Shoseyov, D" uniqKey="Shoseyov D">D Shoseyov</name>
</author>
<author><name sortKey="Cohen, M" uniqKey="Cohen M">M Cohen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sermet Gaudelus, I" uniqKey="Sermet Gaudelus I">I Sermet-Gaudelus</name>
</author>
<author><name sortKey="Boeck, Kd" uniqKey="Boeck K">KD Boeck</name>
</author>
<author><name sortKey="Casimir, Gj" uniqKey="Casimir G">GJ Casimir</name>
</author>
<author><name sortKey="Vermeulen, F" uniqKey="Vermeulen F">F Vermeulen</name>
</author>
<author><name sortKey="Leal, T" uniqKey="Leal T">T Leal</name>
</author>
<author><name sortKey="Mogenet, A" uniqKey="Mogenet A">A Mogenet</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bushby, K" uniqKey="Bushby K">K Bushby</name>
</author>
<author><name sortKey="Finkel, R" uniqKey="Finkel R">R Finkel</name>
</author>
<author><name sortKey="Birnkrant, Dj" uniqKey="Birnkrant D">DJ Birnkrant</name>
</author>
<author><name sortKey="Case, Le" uniqKey="Case L">LE Case</name>
</author>
<author><name sortKey="Clemens, Pr" uniqKey="Clemens P">PR Clemens</name>
</author>
<author><name sortKey="Cripe, L" uniqKey="Cripe L">L Cripe</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mcdonald, Cm" uniqKey="Mcdonald C">CM McDonald</name>
</author>
<author><name sortKey="Henricson, Ek" uniqKey="Henricson E">EK Henricson</name>
</author>
<author><name sortKey="Abresch, Rt" uniqKey="Abresch R">RT Abresch</name>
</author>
<author><name sortKey="Florence, Jm" uniqKey="Florence J">JM Florence</name>
</author>
<author><name sortKey="Eagle, M" uniqKey="Eagle M">M Eagle</name>
</author>
<author><name sortKey="Gappmaier, E" uniqKey="Gappmaier E">E Gappmaier</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mcdonald, Cm" uniqKey="Mcdonald C">CM McDonald</name>
</author>
<author><name sortKey="Henricson, Ek" uniqKey="Henricson E">EK Henricson</name>
</author>
<author><name sortKey="Han, Jj" uniqKey="Han J">JJ Han</name>
</author>
<author><name sortKey="Abresch, Rt" uniqKey="Abresch R">RT Abresch</name>
</author>
<author><name sortKey="Nicorici, A" uniqKey="Nicorici A">A Nicorici</name>
</author>
<author><name sortKey="Elfring, Gl" uniqKey="Elfring G">GL Elfring</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mcdonald, Cm" uniqKey="Mcdonald C">CM McDonald</name>
</author>
<author><name sortKey="Henricson, Ek" uniqKey="Henricson E">EK Henricson</name>
</author>
<author><name sortKey="Han, Jj" uniqKey="Han J">JJ Han</name>
</author>
<author><name sortKey="Abresch, Rt" uniqKey="Abresch R">RT Abresch</name>
</author>
<author><name sortKey="Nicorici, A" uniqKey="Nicorici A">A Nicorici</name>
</author>
<author><name sortKey="Atkinson, L" uniqKey="Atkinson L">L Atkinson</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Varni, Jw" uniqKey="Varni J">JW Varni</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hirawat, S" uniqKey="Hirawat S">S Hirawat</name>
</author>
<author><name sortKey="Welch, Em" uniqKey="Welch E">EM Welch</name>
</author>
<author><name sortKey="Elfring, Gl" uniqKey="Elfring G">GL Elfring</name>
</author>
<author><name sortKey="Northcutt, Vj" uniqKey="Northcutt V">VJ Northcutt</name>
</author>
<author><name sortKey="Paushkin, S" uniqKey="Paushkin S">S Paushkin</name>
</author>
<author><name sortKey="Hwang, S" uniqKey="Hwang S">S Hwang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wraith, Je" uniqKey="Wraith J">JE Wraith</name>
</author>
<author><name sortKey="Clarke, La" uniqKey="Clarke L">LA Clarke</name>
</author>
<author><name sortKey="Beck, M" uniqKey="Beck M">M Beck</name>
</author>
<author><name sortKey="Kolodny, Eh" uniqKey="Kolodny E">EH Kolodny</name>
</author>
<author><name sortKey="Pastores, Gm" uniqKey="Pastores G">GM Pastores</name>
</author>
<author><name sortKey="Muenzer, J" uniqKey="Muenzer J">J Muenzer</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Muenzer, J" uniqKey="Muenzer J">J Muenzer</name>
</author>
<author><name sortKey="Wraith, Je" uniqKey="Wraith J">JE Wraith</name>
</author>
<author><name sortKey="Beck, M" uniqKey="Beck M">M Beck</name>
</author>
<author><name sortKey="Giugliani, R" uniqKey="Giugliani R">R Giugliani</name>
</author>
<author><name sortKey="Harmatz, P" uniqKey="Harmatz P">P Harmatz</name>
</author>
<author><name sortKey="Eng, Cm" uniqKey="Eng C">CM Eng</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mallinckrodt, Ch" uniqKey="Mallinckrodt C">CH Mallinckrodt</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mallinckrodt, Ch" uniqKey="Mallinckrodt C">CH Mallinckrodt</name>
</author>
<author><name sortKey="Kenward, Mg" uniqKey="Kenward M">MG Kenward</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Geiger, R" uniqKey="Geiger R">R Geiger</name>
</author>
<author><name sortKey="Strasak, A" uniqKey="Strasak A">A Strasak</name>
</author>
<author><name sortKey="Treml, B" uniqKey="Treml B">B Treml</name>
</author>
<author><name sortKey="K, Gasser" uniqKey="K G">Gasser K</name>
</author>
<author><name sortKey="A, Kleinsasser" uniqKey="A K">Kleinsasser A</name>
</author>
<author><name sortKey="V, Fischer" uniqKey="V F">Fischer V</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Henricson, E" uniqKey="Henricson E">E Henricson</name>
</author>
<author><name sortKey="Abresch, R" uniqKey="Abresch R">R Abresch</name>
</author>
<author><name sortKey="Han, Jj" uniqKey="Han J">JJ Han</name>
</author>
<author><name sortKey="A, Nicorici" uniqKey="A N">Nicorici A</name>
</author>
<author><name sortKey="E, Goudekeller" uniqKey="E G">GoudeKeller E</name>
</author>
<author><name sortKey="G, Elfring" uniqKey="G E">Elfring G</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Escolar, Dm" uniqKey="Escolar D">DM Escolar</name>
</author>
<author><name sortKey="Hache, Lp" uniqKey="Hache L">LP Hache</name>
</author>
<author><name sortKey="Clemens, Pr" uniqKey="Clemens P">PR Clemens</name>
</author>
<author><name sortKey="Cnaan, A" uniqKey="Cnaan A">A Cnaan</name>
</author>
<author><name sortKey="Mcdonald, Cm" uniqKey="Mcdonald C">CM McDonald</name>
</author>
<author><name sortKey="Viswanathan, V" uniqKey="Viswanathan V">V Viswanathan</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mcdonald, Cm" uniqKey="Mcdonald C">CM McDonald</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Vestergaard, P" uniqKey="Vestergaard P">P Vestergaard</name>
</author>
<author><name sortKey="Glerup, H" uniqKey="Glerup H">H Glerup</name>
</author>
<author><name sortKey="Steffensen, Bf" uniqKey="Steffensen B">BF Steffensen</name>
</author>
<author><name sortKey="Rejnmark, L" uniqKey="Rejnmark L">L Rejnmark</name>
</author>
<author><name sortKey="Rahbek, J" uniqKey="Rahbek J">J Rahbek</name>
</author>
<author><name sortKey="Moseklide, L" uniqKey="Moseklide L">L Moseklide</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Worton, Rg" uniqKey="Worton R">RG Worton</name>
</author>
<author><name sortKey="Molnar, Mj" uniqKey="Molnar M">MJ Molnar</name>
</author>
<author><name sortKey="Brais, B" uniqKey="Brais B">B Brais</name>
</author>
<author><name sortKey="Karpati, G" uniqKey="Karpati G">G Karpati</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Kierkegaard, M" uniqKey="Kierkegaard M">M Kierkegaard</name>
</author>
<author><name sortKey="Tollback, A" uniqKey="Tollback A">A Tollback</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mazzone, E" uniqKey="Mazzone E">E Mazzone</name>
</author>
<author><name sortKey="Martinelli, D" uniqKey="Martinelli D">D Martinelli</name>
</author>
<author><name sortKey="Berardinelli, A" uniqKey="Berardinelli A">A Berardinelli</name>
</author>
<author><name sortKey="Messina, S" uniqKey="Messina S">S Messina</name>
</author>
<author><name sortKey="D Amico, A" uniqKey="D Amico A">A D'Amico</name>
</author>
<author><name sortKey="Vasco, G" uniqKey="Vasco G">G Vasco</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mazzone, E" uniqKey="Mazzone E">E Mazzone</name>
</author>
<author><name sortKey="Vasco, G" uniqKey="Vasco G">G Vasco</name>
</author>
<author><name sortKey="Sormani, Mp" uniqKey="Sormani M">MP Sormani</name>
</author>
<author><name sortKey="Torrente, Y" uniqKey="Torrente Y">Y Torrente</name>
</author>
<author><name sortKey="Berardinelli, A" uniqKey="Berardinelli A">A Berardinelli</name>
</author>
<author><name sortKey="Messina, S" uniqKey="Messina S">S Messina</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Henricson, E" uniqKey="Henricson E">E Henricson</name>
</author>
<author><name sortKey="Abresch, R" uniqKey="Abresch R">R Abresch</name>
</author>
<author><name sortKey="Han, Jj" uniqKey="Han J">JJ Han</name>
</author>
<author><name sortKey="Nicorici, A" uniqKey="Nicorici A">A Nicorici</name>
</author>
<author><name sortKey="Goude Keller, E" uniqKey="Goude Keller E">E Goude Keller</name>
</author>
<author><name sortKey="De Bie, E" uniqKey="De Bie E">E de Bie</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mazzone, Es" uniqKey="Mazzone E">ES Mazzone</name>
</author>
<author><name sortKey="Pane, M" uniqKey="Pane M">M Pane</name>
</author>
<author><name sortKey="Sormani, Mp" uniqKey="Sormani M">MP Sormani</name>
</author>
<author><name sortKey="Scalise, R" uniqKey="Scalise R">R Scalise</name>
</author>
<author><name sortKey="Berardinelli, A" uniqKey="Berardinelli A">A Berardinelli</name>
</author>
<author><name sortKey="Messina, S" uniqKey="Messina S">S Messina</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Yilmaz, O" uniqKey="Yilmaz O">O Yilmaz</name>
</author>
<author><name sortKey="Karaduman, A" uniqKey="Karaduman A">A Karaduman</name>
</author>
<author><name sortKey="Topaloglu, H" uniqKey="Topaloglu H">H Topaloglu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kinali, M" uniqKey="Kinali M">M Kinali</name>
</author>
<author><name sortKey="Main, M" uniqKey="Main M">M Main</name>
</author>
<author><name sortKey="Eliahoo, J" uniqKey="Eliahoo J">J Eliahoo</name>
</author>
<author><name sortKey="Messina, S" uniqKey="Messina S">S Messina</name>
</author>
<author><name sortKey="Knight, Rk" uniqKey="Knight R">RK Knight</name>
</author>
<author><name sortKey="Lehovsky, J" uniqKey="Lehovsky J">J Lehovsky</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mcdonald, Cm" uniqKey="Mcdonald C">CM McDonald</name>
</author>
<author><name sortKey="Abresch, Rt" uniqKey="Abresch R">RT Abresch</name>
</author>
<author><name sortKey="Carter, Gt" uniqKey="Carter G">GT Carter</name>
</author>
<author><name sortKey="Fowler Wm, Jr" uniqKey="Fowler Wm J">Jr Fowler WM</name>
</author>
<author><name sortKey="Johnson, Er" uniqKey="Johnson E">ER Johnson</name>
</author>
<author><name sortKey="Kilmer, Dd" uniqKey="Kilmer D">DD Kilmer</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Beenakker, Eac" uniqKey="Beenakker E">EAC Beenakker</name>
</author>
<author><name sortKey="Maurits, Nm" uniqKey="Maurits N">NM Maurits</name>
</author>
<author><name sortKey="Fock, Jm" uniqKey="Fock J">JM Fock</name>
</author>
<author><name sortKey="Brouwer, Of" uniqKey="Brouwer O">OF Brouwer</name>
</author>
<author><name sortKey="Van Der Hoeven, Jh" uniqKey="Van Der Hoeven J">JH van der Hoeven</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Uchikawa, K" uniqKey="Uchikawa K">K Uchikawa</name>
</author>
<author><name sortKey="Liu, M" uniqKey="Liu M">M Liu</name>
</author>
<author><name sortKey="Hanayama, K" uniqKey="Hanayama K">K Hanayama</name>
</author>
<author><name sortKey="Tsuji, T" uniqKey="Tsuji T">T Tsuji</name>
</author>
<author><name sortKey="Fujiwara, T" uniqKey="Fujiwara T">T Fujiwara</name>
</author>
<author><name sortKey="Chino, N" uniqKey="Chino N">N Chino</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Li, M" uniqKey="Li M">M Li</name>
</author>
<author><name sortKey="Andersson Lendahl, M" uniqKey="Andersson Lendahl M">M Andersson-Lendahl</name>
</author>
<author><name sortKey="Sejersen, T" uniqKey="Sejersen T">T Sejersen</name>
</author>
<author><name sortKey="Arner, A" uniqKey="Arner A">A Arner</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Burke, Jf" uniqKey="Burke J">JF Burke</name>
</author>
<author><name sortKey="Mogg, Ae" uniqKey="Mogg A">AE Mogg</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lai, Ch" uniqKey="Lai C">CH Lai</name>
</author>
<author><name sortKey="Chun, Hh" uniqKey="Chun H">HH Chun</name>
</author>
<author><name sortKey="Nahas, Sa" uniqKey="Nahas S">SA Nahas</name>
</author>
<author><name sortKey="Mitui, M" uniqKey="Mitui M">M Mitui</name>
</author>
<author><name sortKey="Gamo, Km" uniqKey="Gamo K">KM Gamo</name>
</author>
<author><name sortKey="Du, L" uniqKey="Du L">L Du</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bellais, S" uniqKey="Bellais S">S Bellais</name>
</author>
<author><name sortKey="Le Goff, C" uniqKey="Le Goff C">C Le Goff</name>
</author>
<author><name sortKey="Dagoneau, N" uniqKey="Dagoneau N">N Dagoneau</name>
</author>
<author><name sortKey="Munnich, A" uniqKey="Munnich A">A Munnich</name>
</author>
<author><name sortKey="Cormier Daire, V" uniqKey="Cormier Daire V">V Cormier-Daire</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Brown, Kj" uniqKey="Brown K">KJ Brown</name>
</author>
<author><name sortKey="Marathi, R" uniqKey="Marathi R">R Marathi</name>
</author>
<author><name sortKey="Fiorillo, Aa" uniqKey="Fiorillo A">AA Fiorillo</name>
</author>
<author><name sortKey="Ciccimaro, Ef" uniqKey="Ciccimaro E">EF Ciccimaro</name>
</author>
<author><name sortKey="Sharma, S" uniqKey="Sharma S">S Sharma</name>
</author>
<author><name sortKey="Rowlands, Ds" uniqKey="Rowlands D">DS Rowlands</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Muscle Nerve</journal-id>
<journal-id journal-id-type="iso-abbrev">Muscle Nerve</journal-id>
<journal-id journal-id-type="publisher-id">mus</journal-id>
<journal-title-group><journal-title>Muscle & Nerve</journal-title>
</journal-title-group>
<issn pub-type="ppub">0148-639X</issn>
<issn pub-type="epub">1097-4598</issn>
<publisher><publisher-name>BlackWell Publishing Ltd</publisher-name>
<publisher-loc>Oxford, UK</publisher-loc>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">25042182</article-id>
<article-id pub-id-type="pmc">4241581</article-id>
<article-id pub-id-type="doi">10.1002/mus.24332</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Main Articles</subject>
</subj-group>
</article-categories>
<title-group><article-title>Ataluren treatment of patients with nonsense mutation dystrophinopathy</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Bushby</surname>
<given-names>Katharine</given-names>
<suffix>MD</suffix>
</name>
<xref ref-type="aff" rid="au1">1</xref>
<xref ref-type="author-notes" rid="fn1">*</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Finkel</surname>
<given-names>Richard</given-names>
<suffix>MD</suffix>
</name>
<xref ref-type="aff" rid="au2">2</xref>
<xref ref-type="author-notes" rid="fn1">*</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Wong</surname>
<given-names>Brenda</given-names>
<suffix>MD</suffix>
</name>
<xref ref-type="aff" rid="au3">3</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Barohn</surname>
<given-names>Richard</given-names>
<suffix>MD</suffix>
</name>
<xref ref-type="aff" rid="au4">4</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Campbell</surname>
<given-names>Craig</given-names>
<suffix>MD</suffix>
</name>
<xref ref-type="aff" rid="au5">5</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Comi</surname>
<given-names>Giacomo P</given-names>
<suffix>MD</suffix>
</name>
<xref ref-type="aff" rid="au6">6</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Connolly</surname>
<given-names>Anne M</given-names>
<suffix>MD</suffix>
</name>
<xref ref-type="aff" rid="au7">7</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Day</surname>
<given-names>John W</given-names>
<suffix>MD PhD</suffix>
</name>
<xref ref-type="aff" rid="au8">8</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Flanigan</surname>
<given-names>Kevin M</given-names>
<suffix>MD</suffix>
</name>
<xref ref-type="aff" rid="au9">9</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Goemans</surname>
<given-names>Nathalie</given-names>
<suffix>MD</suffix>
</name>
<xref ref-type="aff" rid="au10">10</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Jones</surname>
<given-names>Kristi J</given-names>
<suffix>MD PhD</suffix>
</name>
<xref ref-type="aff" rid="au11">11</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Mercuri</surname>
<given-names>Eugenio</given-names>
<suffix>MD</suffix>
</name>
<xref ref-type="aff" rid="au12">12</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Quinlivan</surname>
<given-names>Ros</given-names>
<suffix>MD</suffix>
</name>
<xref ref-type="aff" rid="au13">13</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Renfroe</surname>
<given-names>James B</given-names>
<suffix>MD</suffix>
</name>
<xref ref-type="aff" rid="au14">14</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Russman</surname>
<given-names>Barry</given-names>
<suffix>MD</suffix>
</name>
<xref ref-type="aff" rid="au15">15</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Ryan</surname>
<given-names>Monique M</given-names>
<suffix>MED BS</suffix>
</name>
<xref ref-type="aff" rid="au16">16</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Tulinius</surname>
<given-names>Mar</given-names>
<suffix>MD PhD</suffix>
</name>
<xref ref-type="aff" rid="au17">17</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Voit</surname>
<given-names>Thomas</given-names>
<suffix>MD</suffix>
</name>
<xref ref-type="aff" rid="au18">18</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Moore</surname>
<given-names>Steven A</given-names>
<suffix>MD PhD</suffix>
</name>
<xref ref-type="aff" rid="au19">19</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Lee Sweeney</surname>
<given-names>H</given-names>
<suffix>PhD</suffix>
</name>
<xref ref-type="aff" rid="au20">20</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Abresch</surname>
<given-names>Richard T</given-names>
<suffix>MS</suffix>
</name>
<xref ref-type="aff" rid="au21">21</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Coleman</surname>
<given-names>Kim L</given-names>
<suffix>MS</suffix>
</name>
<xref ref-type="aff" rid="au22">22</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Eagle</surname>
<given-names>Michelle</given-names>
<suffix>PhD</suffix>
</name>
<xref ref-type="aff" rid="au1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Florence</surname>
<given-names>Julaine</given-names>
<suffix>PhD</suffix>
</name>
<xref ref-type="aff" rid="au7">7</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Gappmaier</surname>
<given-names>Eduard</given-names>
<suffix>PhD</suffix>
</name>
<xref ref-type="aff" rid="au23">23</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Glanzman</surname>
<given-names>Allan M</given-names>
<suffix>DPT</suffix>
</name>
<xref ref-type="aff" rid="au2">2</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Henricson</surname>
<given-names>Erik</given-names>
<suffix>MPH</suffix>
</name>
<xref ref-type="aff" rid="au21">21</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Barth</surname>
<given-names>Jay</given-names>
<suffix>MD</suffix>
</name>
<xref ref-type="aff" rid="au24">24</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Elfring</surname>
<given-names>Gary L</given-names>
<suffix>MS</suffix>
</name>
<xref ref-type="aff" rid="au24">24</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Reha</surname>
<given-names>Allen</given-names>
<suffix>MS</suffix>
</name>
<xref ref-type="aff" rid="au24">24</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Spiegel</surname>
<given-names>Robert J</given-names>
<suffix>MD</suffix>
</name>
<xref ref-type="aff" rid="au24">24</xref>
</contrib>
<contrib contrib-type="author"><name><surname>O'donnell</surname>
<given-names>Michael W</given-names>
<suffix>MS</suffix>
</name>
<xref ref-type="aff" rid="au24">24</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Peltz</surname>
<given-names>Stuart W</given-names>
<suffix>PhD</suffix>
</name>
<xref ref-type="aff" rid="au24">24</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Mcdonald</surname>
<given-names>Craig M</given-names>
<suffix>MD</suffix>
</name>
<xref ref-type="aff" rid="au21">21</xref>
<xref ref-type="corresp" rid="cor1"></xref>
</contrib>
<contrib contrib-type="author"><name><surname>FOR THE PTC124-GD-007-DMD STUDY GROUP</surname>
<given-names></given-names>
</name>
<xref ref-type="author-notes" rid="fn2">**</xref>
</contrib>
<aff id="au1"><label>1</label>
<institution>Institute of Genetic Medicine, Newcastle University</institution>
<addr-line>Newcastle upon Tyne, United Kingdom</addr-line>
</aff>
<aff id="au2"><label>2</label>
<institution>The Children's Hospital of Philadelphia</institution>
<addr-line>Pennsylvania, USA</addr-line>
</aff>
<aff id="au3"><label>3</label>
<institution>Cincinnati Children's Hospital Medical Center</institution>
<addr-line>Ohio, USA</addr-line>
</aff>
<aff id="au4"><label>4</label>
<institution>University of Kansas Medical Center</institution>
<addr-line>Kansas, USA</addr-line>
</aff>
<aff id="au5"><label>5</label>
<institution>University of Western Ontario</institution>
<addr-line>London, Ontario, Canada</addr-line>
</aff>
<aff id="au6"><label>6</label>
<institution>Dino Ferrari Centre, Department of Neurological Sciences, University of Milan</institution>
<addr-line>I.R.C.C.S. Foundation Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy</addr-line>
</aff>
<aff id="au7"><label>7</label>
<institution>Washington University School of Medicine at St. Louis</institution>
<addr-line>Missouri, USA</addr-line>
</aff>
<aff id="au8"><label>8</label>
<institution>University of Minnesota</institution>
<addr-line>Minneapolis, Minnesota, USA</addr-line>
</aff>
<aff id="au9"><label>9</label>
<institution>Nationwide Children's Hospital and the Ohio State University</institution>
<addr-line>Columbus, Ohio, USA</addr-line>
</aff>
<aff id="au10"><label>10</label>
<institution>University Hospitals Leuven</institution>
<addr-line>Leuven, Belgium</addr-line>
</aff>
<aff id="au11"><label>11</label>
<institution>Department of Clinical Genetics, Sydney Children's Hospital Network, and Disciplines of Genetics and Paediatrics and Child Health, Faculty of Medicine University of Sydney</institution>
<addr-line>Australia</addr-line>
</aff>
<aff id="au12"><label>12</label>
<institution>Pediatric Neurology Unit, Polilcinico Gemelli, Università Cattolica Sacro Cuore</institution>
<addr-line>Rome, Italy</addr-line>
</aff>
<aff id="au13"><label>13</label>
<institution>The Institute of Neurology</institution>
<addr-line>London, United Kingdom</addr-line>
</aff>
<aff id="au14"><label>14</label>
<institution>Northwest Florida Clinical Research Group</institution>
<addr-line>Florida, USA</addr-line>
</aff>
<aff id="au15"><label>15</label>
<institution>Oregon Health & Science University and Shriners Hospital for Children</institution>
<addr-line>Oregon, USA</addr-line>
</aff>
<aff id="au16"><label>16</label>
<institution>Royal Children's Hospital, Murdoch Childrens Research Institute and University of Melbourne</institution>
<addr-line>Parkville, Victoria, Australia</addr-line>
</aff>
<aff id="au17"><label>17</label>
<institution>Department of Pediatrics, The University of Gothenburg</institution>
<addr-line>Gothenburg, Sweden</addr-line>
</aff>
<aff id="au18"><label>18</label>
<institution>Institut de Myologie, University Pierre et Marie Curie Paris 6</institution>
<addr-line>UM 76, INSERM U 974, CNRS UMR 7215, Paris, France</addr-line>
</aff>
<aff id="au19"><label>19</label>
<institution>University of Iowa</institution>
<addr-line>Iowa, USA</addr-line>
</aff>
<aff id="au20"><label>20</label>
<institution>University of Pennsylvania</institution>
<addr-line>Pennsylvania, USA</addr-line>
</aff>
<aff id="au21"><label>21</label>
<institution>UC Davis Children's Hospital, Lawrence J. Ellison Ambulatory Care Center, Physical Medicine & Rehabilitation</institution>
<addr-line>4860 Y St., Suite 1700, Sacramento, California, 95817, USA</addr-line>
</aff>
<aff id="au22"><label>22</label>
<institution>OrthoCare Innovations</institution>
<addr-line>Mountlake Terrace, Washington, USA</addr-line>
</aff>
<aff id="au23"><label>23</label>
<institution>University of Utah School of Medicine</institution>
<addr-line>Salt Lake City, Utah, USA</addr-line>
</aff>
<aff id="au24"><label>24</label>
<institution>PTC Therapeutics</institution>
<addr-line>South Plainfield, New Jersey, USA</addr-line>
</aff>
</contrib-group>
<author-notes><corresp id="cor1">Correspondence to: C.M. McDonald; e-mail: <email>cmmcdonald@ucdavis.edu</email>
</corresp>
<fn id="fn1"><label>*</label>
<p>Drs. Bushby and Finkel, contributed equally to this work.</p>
</fn>
<fn id="fn2"><label>**</label>
<p>The members of the PTC124-GD-007-DMD Study Group are listed in the Supplementary Appendix (available online).</p>
</fn>
</author-notes>
<pub-date pub-type="ppub"><month>10</month>
<year>2014</year>
</pub-date>
<pub-date pub-type="epub"><day>22</day>
<month>9</month>
<year>2014</year>
</pub-date>
<volume>50</volume>
<issue>4</issue>
<fpage>477</fpage>
<lpage>487</lpage>
<history><date date-type="accepted"><day>01</day>
<month>7</month>
<year>2014</year>
</date>
</history>
<permissions><copyright-statement>Copyright © 2014 Wiley Periodicals, Inc.</copyright-statement>
<copyright-year>2014</copyright-year>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc-nd/3.0/"><license-p>This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.</license-p>
</license>
</permissions>
<abstract><p><italic>Introduction</italic>
: Dystrophinopathy is a rare, severe muscle disorder, and nonsense mutations are found in 13% of cases. Ataluren was developed to enable ribosomal readthrough of premature stop codons in nonsense mutation (nm) genetic disorders. <italic>Methods</italic>
: Randomized, double-blind, placebo-controlled study; males ≥5 years with nm-dystrophinopathy received study drug orally 3 times daily, ataluren 10, 10, 20 mg/kg (<italic>N</italic>
= 57); ataluren 20, 20, 40 mg/kg (<italic>N</italic>
= 60); or placebo (<italic>N</italic>
= 57) for 48 weeks. The primary endpoint was change in 6-Minute Walk Distance (6MWD) at Week 48. <italic>Results</italic>
: Ataluren was generally well tolerated. The primary endpoint favored ataluren 10, 10, 20 mg/kg versus placebo; the week 48 6MWD Δ = 31.3 meters, <italic>post hoc P</italic>
= 0.056. Secondary endpoints (timed function tests) showed meaningful differences between ataluren 10, 10, 20 mg/kg, and placebo. <italic>Conclusions</italic>
: As the first investigational new drug targeting the underlying cause of nm-dystrophinopathy, ataluren offers promise as a treatment for this orphan genetic disorder with high unmet medical need. <italic>Muscle Nerve</italic>
<bold>50</bold>
: 477–487, 2014</p>
</abstract>
<kwd-group><kwd>Duchenne muscular dystrophy</kwd>
<kwd>genetic</kwd>
<kwd>pediatric</kwd>
<kwd>nonsense mutation</kwd>
<kwd>orphan</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
<affiliations><list><country><li>Australie</li>
<li>Belgique</li>
<li>Canada</li>
<li>France</li>
<li>Italie</li>
<li>Royaume-Uni</li>
<li>Suède</li>
<li>États-Unis</li>
</country>
<region><li>Lombardie</li>
<li>Minnesota</li>
<li>New Jersey</li>
<li>Ohio</li>
<li>Utah</li>
<li>Washington (État)</li>
<li>Île-de-France</li>
</region>
<settlement><li>Milan</li>
<li>Paris</li>
</settlement>
</list>
<tree><noCountry><name sortKey="Jones, Kristi J" sort="Jones, Kristi J" uniqKey="Jones K" first="Kristi J" last="Jones">Kristi J. Jones</name>
</noCountry>
<country name="Royaume-Uni"><noRegion><name sortKey="Bushby, Katharine" sort="Bushby, Katharine" uniqKey="Bushby K" first="Katharine" last="Bushby">Katharine Bushby</name>
</noRegion>
<name sortKey="Eagle, Michelle" sort="Eagle, Michelle" uniqKey="Eagle M" first="Michelle" last="Eagle">Michelle Eagle</name>
<name sortKey="Quinlivan, Ros" sort="Quinlivan, Ros" uniqKey="Quinlivan R" first="Ros" last="Quinlivan">Ros Quinlivan</name>
</country>
<country name="États-Unis"><noRegion><name sortKey="Finkel, Richard" sort="Finkel, Richard" uniqKey="Finkel R" first="Richard" last="Finkel">Richard Finkel</name>
</noRegion>
<name sortKey="Abresch, Richard T" sort="Abresch, Richard T" uniqKey="Abresch R" first="Richard T" last="Abresch">Richard T. Abresch</name>
<name sortKey="Barohn, Richard" sort="Barohn, Richard" uniqKey="Barohn R" first="Richard" last="Barohn">Richard Barohn</name>
<name sortKey="Barth, Jay" sort="Barth, Jay" uniqKey="Barth J" first="Jay" last="Barth">Jay Barth</name>
<name sortKey="Coleman, Kim L" sort="Coleman, Kim L" uniqKey="Coleman K" first="Kim L" last="Coleman">Kim L. Coleman</name>
<name sortKey="Connolly, Anne M" sort="Connolly, Anne M" uniqKey="Connolly A" first="Anne M" last="Connolly">Anne M. Connolly</name>
<name sortKey="Day, John W" sort="Day, John W" uniqKey="Day J" first="John W" last="Day">John W. Day</name>
<name sortKey="Elfring, Gary L" sort="Elfring, Gary L" uniqKey="Elfring G" first="Gary L" last="Elfring">Gary L. Elfring</name>
<name sortKey="Flanigan, Kevin M" sort="Flanigan, Kevin M" uniqKey="Flanigan K" first="Kevin M" last="Flanigan">Kevin M. Flanigan</name>
<name sortKey="Florence, Julaine" sort="Florence, Julaine" uniqKey="Florence J" first="Julaine" last="Florence">Julaine Florence</name>
<name sortKey="Gappmaier, Eduard" sort="Gappmaier, Eduard" uniqKey="Gappmaier E" first="Eduard" last="Gappmaier">Eduard Gappmaier</name>
<name sortKey="Glanzman, Allan M" sort="Glanzman, Allan M" uniqKey="Glanzman A" first="Allan M" last="Glanzman">Allan M. Glanzman</name>
<name sortKey="Henricson, Erik" sort="Henricson, Erik" uniqKey="Henricson E" first="Erik" last="Henricson">Erik Henricson</name>
<name sortKey="Lee Sweeney, H" sort="Lee Sweeney, H" uniqKey="Lee Sweeney H" first="H" last="Lee Sweeney">H. Lee Sweeney</name>
<name sortKey="Mcdonald, Craig M" sort="Mcdonald, Craig M" uniqKey="Mcdonald C" first="Craig M" last="Mcdonald">Craig M. Mcdonald</name>
<name sortKey="Moore, Steven A" sort="Moore, Steven A" uniqKey="Moore S" first="Steven A" last="Moore">Steven A. Moore</name>
<name sortKey="O Donnell, Michael W" sort="O Donnell, Michael W" uniqKey="O Donnell M" first="Michael W" last="O'Donnell">Michael W. O'Donnell</name>
<name sortKey="Peltz, Stuart W" sort="Peltz, Stuart W" uniqKey="Peltz S" first="Stuart W" last="Peltz">Stuart W. Peltz</name>
<name sortKey="Reha, Allen" sort="Reha, Allen" uniqKey="Reha A" first="Allen" last="Reha">Allen Reha</name>
<name sortKey="Renfroe, James B" sort="Renfroe, James B" uniqKey="Renfroe J" first="James B" last="Renfroe">James B. Renfroe</name>
<name sortKey="Russman, Barry" sort="Russman, Barry" uniqKey="Russman B" first="Barry" last="Russman">Barry Russman</name>
<name sortKey="Spiegel, Robert J" sort="Spiegel, Robert J" uniqKey="Spiegel R" first="Robert J" last="Spiegel">Robert J. Spiegel</name>
<name sortKey="Wong, Brenda" sort="Wong, Brenda" uniqKey="Wong B" first="Brenda" last="Wong">Brenda Wong</name>
</country>
<country name="Canada"><noRegion><name sortKey="Campbell, Craig" sort="Campbell, Craig" uniqKey="Campbell C" first="Craig" last="Campbell">Craig Campbell</name>
</noRegion>
</country>
<country name="Italie"><region name="Lombardie"><name sortKey="Comi, Giacomo P" sort="Comi, Giacomo P" uniqKey="Comi G" first="Giacomo P" last="Comi">Giacomo P. Comi</name>
</region>
<name sortKey="Mercuri, Eugenio" sort="Mercuri, Eugenio" uniqKey="Mercuri E" first="Eugenio" last="Mercuri">Eugenio Mercuri</name>
</country>
<country name="Belgique"><noRegion><name sortKey="Goemans, Nathalie" sort="Goemans, Nathalie" uniqKey="Goemans N" first="Nathalie" last="Goemans">Nathalie Goemans</name>
</noRegion>
</country>
<country name="Australie"><noRegion><name sortKey="Ryan, Monique M" sort="Ryan, Monique M" uniqKey="Ryan M" first="Monique M" last="Ryan">Monique M. Ryan</name>
</noRegion>
</country>
<country name="Suède"><noRegion><name sortKey="Tulinius, Mar" sort="Tulinius, Mar" uniqKey="Tulinius M" first="Mar" last="Tulinius">Mar Tulinius</name>
</noRegion>
</country>
<country name="France"><region name="Île-de-France"><name sortKey="Voit, Thomas" sort="Voit, Thomas" uniqKey="Voit T" first="Thomas" last="Voit">Thomas Voit</name>
</region>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Ncbi/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001C39 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd -nk 001C39 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Asie |area= AustralieFrV1 |flux= Ncbi |étape= Merge |type= RBID |clé= PMC:4241581 |texte= Ataluren treatment of patients with nonsense mutation dystrophinopathy }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/RBID.i -Sk "pubmed:25042182" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd \ | NlmPubMed2Wicri -a AustralieFrV1
![]() | This area was generated with Dilib version V0.6.33. | ![]() |