Vemurafenib in metastatic melanoma patients with brain metastases: an open-label, single-arm, phase 2, multicentre study.
Identifieur interne : 004058 ( Ncbi/Curation ); précédent : 004057; suivant : 004059Vemurafenib in metastatic melanoma patients with brain metastases: an open-label, single-arm, phase 2, multicentre study.
Auteurs : G A Mcarthur [Australie] ; M. Maio [Italie] ; A. Arance [Espagne] ; P. Nathan [Royaume-Uni] ; C. Blank [Pays-Bas] ; M-F Avril [France] ; C. Garbe ; A. Hauschild ; D. Schadendorf [Allemagne] ; O. Hamid [États-Unis] ; M. Fluck [Allemagne] ; M. Thebeau [États-Unis] ; J. Schachter [Israël] ; R. Kefford [Australie] ; M. Chamberlain [États-Unis] ; M. Makrutzki [Suisse] ; S. Robson [Suisse] ; R. Gonzalez ; K. Margolin [États-Unis]Source :
- Annals of oncology : official journal of the European Society for Medical Oncology [ 1569-8041 ] ; 2017.
Abstract
Vemurafenib has shown activity in patients with BRAFV600 mutated melanoma with brain metastases (BM). This phase 2 study evaluated vemurafenib in patients with/without prior treatment for BM.
DOI: 10.1093/annonc/mdw641
PubMed: 27993793
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C. Garbe<affiliation><nlm:affiliation>Department of Dermatology, University Hospital Tuebingen, Tuebingen.</nlm:affiliation>
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<affiliation><nlm:affiliation>Department of Dermatology, University Hospital Schleswig-Holstein (UKSH), Campus Kiel, Kiel.</nlm:affiliation>
<wicri:noCountry code="subField">Kiel</wicri:noCountry>
</affiliation>
<affiliation><nlm:affiliation>University of Colorado Cancer Center, Aurora.</nlm:affiliation>
<wicri:noCountry code="subField">Aurora</wicri:noCountry>
</affiliation>
Le document en format XML
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<front><div type="abstract" xml:lang="en">Vemurafenib has shown activity in patients with BRAFV600 mutated melanoma with brain metastases (BM). This phase 2 study evaluated vemurafenib in patients with/without prior treatment for BM.</div>
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