Effects of rituximab in connective tissue disorders related interstitial lung disease.
Identifieur interne : 003D18 ( Ncbi/Curation ); précédent : 003D17; suivant : 003D19Effects of rituximab in connective tissue disorders related interstitial lung disease.
Auteurs : Gemma Lepri [France] ; Jerome Avouac [France] ; Paolo Air [Italie] ; Francisco Anguita Santos ; Silvia Bellando-Randone [Italie] ; Jelena Blagojevic [Italie] ; Francisco Garcia Hernàndez ; Jose Antonio Gonzalez Nieto ; Serena Guiducci [Italie] ; Suzana Jordan [Suisse] ; Vidya Limaye [Australie] ; Britta Maurer [Suisse] ; Albert Selva-O'Callaghan ; Valeria Riccieri [Italie] ; Oliver Distler [Suisse] ; Marco Matucci-Cerinic [Italie] ; Yannick Allanore [France]Source :
- Clinical and experimental rheumatology [ 0392-856X ]
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Capacité vitale, Facteurs temps, Femelle, Humains, Immunosuppresseurs (effets indésirables), Immunosuppresseurs (usage thérapeutique), Maladies du tissu conjonctif (), Maladies du tissu conjonctif (diagnostic), Maladies du tissu conjonctif (traitement médicamenteux), Mâle, Pneumopathies interstitielles (diagnostic), Pneumopathies interstitielles (physiopathologie), Pneumopathies interstitielles (traitement médicamenteux), Pneumopathies interstitielles (étiologie), Poumon (), Poumon (physiopathologie), Rituximab (effets indésirables), Rituximab (usage thérapeutique), Récupération fonctionnelle, Résultat thérapeutique, Sujet âgé, Tests de la fonction respiratoire, Études rétrospectives, Évolution de la maladie.
- MESH :
- diagnostic : Maladies du tissu conjonctif, Pneumopathies interstitielles.
- effets indésirables : Immunosuppresseurs, Rituximab.
- physiopathologie : Pneumopathies interstitielles, Poumon.
- traitement médicamenteux : Maladies du tissu conjonctif, Pneumopathies interstitielles.
- usage thérapeutique : Immunosuppresseurs, Rituximab.
- étiologie : Pneumopathies interstitielles.
- Adulte, Adulte d'âge moyen, Capacité vitale, Facteurs temps, Femelle, Humains, Maladies du tissu conjonctif, Mâle, Poumon, Récupération fonctionnelle, Résultat thérapeutique, Sujet âgé, Tests de la fonction respiratoire, Études rétrospectives, Évolution de la maladie.
English descriptors
- KwdEn :
- Adult, Aged, Connective Tissue Diseases (complications), Connective Tissue Diseases (diagnosis), Connective Tissue Diseases (drug therapy), Disease Progression, Female, Humans, Immunosuppressive Agents (adverse effects), Immunosuppressive Agents (therapeutic use), Lung (drug effects), Lung (physiopathology), Lung Diseases, Interstitial (diagnosis), Lung Diseases, Interstitial (drug therapy), Lung Diseases, Interstitial (etiology), Lung Diseases, Interstitial (physiopathology), Male, Middle Aged, Recovery of Function, Respiratory Function Tests, Retrospective Studies, Rituximab (adverse effects), Rituximab (therapeutic use), Time Factors, Treatment Outcome, Vital Capacity.
- MESH :
- chemical , adverse effects : Immunosuppressive Agents, Rituximab.
- complications : Connective Tissue Diseases.
- diagnosis : Connective Tissue Diseases, Lung Diseases, Interstitial.
- drug effects : Lung.
- drug therapy : Connective Tissue Diseases, Lung Diseases, Interstitial.
- etiology : Lung Diseases, Interstitial.
- physiopathology : Lung, Lung Diseases, Interstitial.
- chemical , therapeutic use : Immunosuppressive Agents, Rituximab.
- Adult, Aged, Disease Progression, Female, Humans, Male, Middle Aged, Recovery of Function, Respiratory Function Tests, Retrospective Studies, Time Factors, Treatment Outcome, Vital Capacity.
Abstract
Interstitial lung disease (ILD) is a key prognostic factor in connective tissue disorders (CTDs). The aim of our study was to assess the changes in pulmonary functional tests (PFTs) in various CTDs, including anti-synthetase syndrome (SYN), systemic sclerosis (SSc) and mixed connective tissue disorder (MCTD), following the use of rituximab therapy.
PubMed: 27749242
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Francisco Anguita Santos<affiliation><nlm:affiliation>Hospital Clinico San Cecilio, Granada, Spain; on behalf of GEAS-SEMI (Grupo Enfermedades Autoinmune Sistémicas)-(Sociedad Española de Medicina Interna).</nlm:affiliation>
<wicri:noCountry code="subField">Spain; on behalf of GEAS-SEMI (Grupo Enfermedades Autoinmune Sistémicas)-(Sociedad Española de Medicina Interna)</wicri:noCountry>
</affiliation>
<affiliation><nlm:affiliation>Hospital Virgen del Rocio, Department of Internal Medicine, Sevilla, Spain; on behalf of GEAS-SEMI (Grupo Enfermedades Autoinmune Sistémicas)-(Sociedad Española de Medicina Interna).</nlm:affiliation>
<wicri:noCountry code="subField">Spain; on behalf of GEAS-SEMI (Grupo Enfermedades Autoinmune Sistémicas)-(Sociedad Española de Medicina Interna)</wicri:noCountry>
</affiliation>
<affiliation><nlm:affiliation>Hospital Can Misses, Autoimmune Disease Unit, Internal Medicine, Ibiza, Spain; on behalf of GEAS-SEMI (Grupo Enfermedades Autoinmune Sistémicas)-(Sociedad Española de Medicina Interna).</nlm:affiliation>
<wicri:noCountry code="subField">Spain; on behalf of GEAS-SEMI (Grupo Enfermedades Autoinmune Sistémicas)-(Sociedad Española de Medicina Interna)</wicri:noCountry>
</affiliation>
<affiliation><nlm:affiliation>Vall D'Hebron General Hospital, Autonoma Univeristy of Barcelona, Internal Medicine, Barcelona, Spain; on behalf of GEAS-SEMI (Grupo Enfermedades Autoinmune Sistémicas)-(Sociedad Española de Medicina Interna).</nlm:affiliation>
<wicri:noCountry code="subField">Spain; on behalf of GEAS-SEMI (Grupo Enfermedades Autoinmune Sistémicas)-(Sociedad Española de Medicina Interna)</wicri:noCountry>
</affiliation>
Le document en format XML
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<author><name sortKey="Lepri, Gemma" sort="Lepri, Gemma" uniqKey="Lepri G" first="Gemma" last="Lepri">Gemma Lepri</name>
<affiliation wicri:level="3"><nlm:affiliation>Dept. of Clinical and Experimental Medicine, AOUC, University of Florence, Italy; and Paris Descartes University, Rheumatology A Dept., APHP, Cochin Hospital, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Dept. of Clinical and Experimental Medicine, AOUC, University of Florence, Italy; and Paris Descartes University, Rheumatology A Dept., APHP, Cochin Hospital, Paris</wicri:regionArea>
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<author><name sortKey="Avouac, Jerome" sort="Avouac, Jerome" uniqKey="Avouac J" first="Jerome" last="Avouac">Jerome Avouac</name>
<affiliation wicri:level="3"><nlm:affiliation>Paris Descartes University, Rheumatology A Department, APHP, Cochin Hospital, Paris, France.</nlm:affiliation>
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<author><name sortKey="Air, Paolo" sort="Air, Paolo" uniqKey="Air P" first="Paolo" last="Air">Paolo Air</name>
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<author><name sortKey="Anguita Santos, Francisco" sort="Anguita Santos, Francisco" uniqKey="Anguita Santos F" first="Francisco" last="Anguita Santos">Francisco Anguita Santos</name>
<affiliation><nlm:affiliation>Hospital Clinico San Cecilio, Granada, Spain; on behalf of GEAS-SEMI (Grupo Enfermedades Autoinmune Sistémicas)-(Sociedad Española de Medicina Interna).</nlm:affiliation>
<wicri:noCountry code="subField">Spain; on behalf of GEAS-SEMI (Grupo Enfermedades Autoinmune Sistémicas)-(Sociedad Española de Medicina Interna)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Bellando Randone, Silvia" sort="Bellando Randone, Silvia" uniqKey="Bellando Randone S" first="Silvia" last="Bellando-Randone">Silvia Bellando-Randone</name>
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<country xml:lang="fr">Italie</country>
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<author><name sortKey="Blagojevic, Jelena" sort="Blagojevic, Jelena" uniqKey="Blagojevic J" first="Jelena" last="Blagojevic">Jelena Blagojevic</name>
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<country xml:lang="fr">Italie</country>
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<author><name sortKey="Garcia Hernandez, Francisco" sort="Garcia Hernandez, Francisco" uniqKey="Garcia Hernandez F" first="Francisco" last="Garcia Hernàndez">Francisco Garcia Hernàndez</name>
<affiliation><nlm:affiliation>Hospital Virgen del Rocio, Department of Internal Medicine, Sevilla, Spain; on behalf of GEAS-SEMI (Grupo Enfermedades Autoinmune Sistémicas)-(Sociedad Española de Medicina Interna).</nlm:affiliation>
<wicri:noCountry code="subField">Spain; on behalf of GEAS-SEMI (Grupo Enfermedades Autoinmune Sistémicas)-(Sociedad Española de Medicina Interna)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Gonzalez Nieto, Jose Antonio" sort="Gonzalez Nieto, Jose Antonio" uniqKey="Gonzalez Nieto J" first="Jose Antonio" last="Gonzalez Nieto">Jose Antonio Gonzalez Nieto</name>
<affiliation><nlm:affiliation>Hospital Can Misses, Autoimmune Disease Unit, Internal Medicine, Ibiza, Spain; on behalf of GEAS-SEMI (Grupo Enfermedades Autoinmune Sistémicas)-(Sociedad Española de Medicina Interna).</nlm:affiliation>
<wicri:noCountry code="subField">Spain; on behalf of GEAS-SEMI (Grupo Enfermedades Autoinmune Sistémicas)-(Sociedad Española de Medicina Interna)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Guiducci, Serena" sort="Guiducci, Serena" uniqKey="Guiducci S" first="Serena" last="Guiducci">Serena Guiducci</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Clinical and Experimental Medicine, AOUC, University of Florence, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Clinical and Experimental Medicine, AOUC, University of Florence</wicri:regionArea>
<wicri:noRegion>University of Florence</wicri:noRegion>
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<author><name sortKey="Jordan, Suzana" sort="Jordan, Suzana" uniqKey="Jordan S" first="Suzana" last="Jordan">Suzana Jordan</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Rheumatology, University Hospital Zurich, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Rheumatology, University Hospital Zurich</wicri:regionArea>
<wicri:noRegion>University Hospital Zurich</wicri:noRegion>
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<author><name sortKey="Limaye, Vidya" sort="Limaye, Vidya" uniqKey="Limaye V" first="Vidya" last="Limaye">Vidya Limaye</name>
<affiliation wicri:level="1"><nlm:affiliation>Royal Adelaide Hospital, University of Adelaide, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Royal Adelaide Hospital, University of Adelaide</wicri:regionArea>
<wicri:noRegion>University of Adelaide</wicri:noRegion>
</affiliation>
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<author><name sortKey="Maurer, Britta" sort="Maurer, Britta" uniqKey="Maurer B" first="Britta" last="Maurer">Britta Maurer</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Rheumatology, University Hospital Zurich, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Rheumatology, University Hospital Zurich</wicri:regionArea>
<wicri:noRegion>University Hospital Zurich</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Selva O Callaghan, Albert" sort="Selva O Callaghan, Albert" uniqKey="Selva O Callaghan A" first="Albert" last="Selva-O'Callaghan">Albert Selva-O'Callaghan</name>
<affiliation><nlm:affiliation>Vall D'Hebron General Hospital, Autonoma Univeristy of Barcelona, Internal Medicine, Barcelona, Spain; on behalf of GEAS-SEMI (Grupo Enfermedades Autoinmune Sistémicas)-(Sociedad Española de Medicina Interna).</nlm:affiliation>
<wicri:noCountry code="subField">Spain; on behalf of GEAS-SEMI (Grupo Enfermedades Autoinmune Sistémicas)-(Sociedad Española de Medicina Interna)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Riccieri, Valeria" sort="Riccieri, Valeria" uniqKey="Riccieri V" first="Valeria" last="Riccieri">Valeria Riccieri</name>
<affiliation wicri:level="3"><nlm:affiliation>Sapienza University of Rome, Department of Internal Medicine and Medical Specialities, Rome, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
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<region nuts="2">Latium</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Distler, Oliver" sort="Distler, Oliver" uniqKey="Distler O" first="Oliver" last="Distler">Oliver Distler</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Rheumatology, University Hospital Zurich, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Rheumatology, University Hospital Zurich</wicri:regionArea>
<wicri:noRegion>University Hospital Zurich</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Matucci Cerinic, Marco" sort="Matucci Cerinic, Marco" uniqKey="Matucci Cerinic M" first="Marco" last="Matucci-Cerinic">Marco Matucci-Cerinic</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Clinical and Experimental Medicine, AOUC, University of Florence, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Clinical and Experimental Medicine, AOUC, University of Florence</wicri:regionArea>
<wicri:noRegion>University of Florence</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Allanore, Yannick" sort="Allanore, Yannick" uniqKey="Allanore Y" first="Yannick" last="Allanore">Yannick Allanore</name>
<affiliation wicri:level="3"><nlm:affiliation>Paris Descartes University, Rheumatology A Department, APHP, Cochin Hospital, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Paris Descartes University, Rheumatology A Department, APHP, Cochin Hospital, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
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</titleStmt>
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<date when="????"><PubDate><MedlineDate>2016 Sep-Oct</MedlineDate>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Effects of rituximab in connective tissue disorders related interstitial lung disease.</title>
<author><name sortKey="Lepri, Gemma" sort="Lepri, Gemma" uniqKey="Lepri G" first="Gemma" last="Lepri">Gemma Lepri</name>
<affiliation wicri:level="3"><nlm:affiliation>Dept. of Clinical and Experimental Medicine, AOUC, University of Florence, Italy; and Paris Descartes University, Rheumatology A Dept., APHP, Cochin Hospital, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Dept. of Clinical and Experimental Medicine, AOUC, University of Florence, Italy; and Paris Descartes University, Rheumatology A Dept., APHP, Cochin Hospital, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Avouac, Jerome" sort="Avouac, Jerome" uniqKey="Avouac J" first="Jerome" last="Avouac">Jerome Avouac</name>
<affiliation wicri:level="3"><nlm:affiliation>Paris Descartes University, Rheumatology A Department, APHP, Cochin Hospital, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Paris Descartes University, Rheumatology A Department, APHP, Cochin Hospital, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Air, Paolo" sort="Air, Paolo" uniqKey="Air P" first="Paolo" last="Air">Paolo Air</name>
<affiliation wicri:level="1"><nlm:affiliation>Spedali Civili di Brescia, Service of Rheumatology and Clinical Immunology, University of Brescia, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Spedali Civili di Brescia, Service of Rheumatology and Clinical Immunology, University of Brescia</wicri:regionArea>
<wicri:noRegion>University of Brescia</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Anguita Santos, Francisco" sort="Anguita Santos, Francisco" uniqKey="Anguita Santos F" first="Francisco" last="Anguita Santos">Francisco Anguita Santos</name>
<affiliation><nlm:affiliation>Hospital Clinico San Cecilio, Granada, Spain; on behalf of GEAS-SEMI (Grupo Enfermedades Autoinmune Sistémicas)-(Sociedad Española de Medicina Interna).</nlm:affiliation>
<wicri:noCountry code="subField">Spain; on behalf of GEAS-SEMI (Grupo Enfermedades Autoinmune Sistémicas)-(Sociedad Española de Medicina Interna)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Bellando Randone, Silvia" sort="Bellando Randone, Silvia" uniqKey="Bellando Randone S" first="Silvia" last="Bellando-Randone">Silvia Bellando-Randone</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Clinical and Experimental Medicine, AOUC, University of Florence, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Clinical and Experimental Medicine, AOUC, University of Florence</wicri:regionArea>
<wicri:noRegion>University of Florence</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Blagojevic, Jelena" sort="Blagojevic, Jelena" uniqKey="Blagojevic J" first="Jelena" last="Blagojevic">Jelena Blagojevic</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Clinical and Experimental Medicine, AOUC, University of Florence, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Clinical and Experimental Medicine, AOUC, University of Florence</wicri:regionArea>
<wicri:noRegion>University of Florence</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Garcia Hernandez, Francisco" sort="Garcia Hernandez, Francisco" uniqKey="Garcia Hernandez F" first="Francisco" last="Garcia Hernàndez">Francisco Garcia Hernàndez</name>
<affiliation><nlm:affiliation>Hospital Virgen del Rocio, Department of Internal Medicine, Sevilla, Spain; on behalf of GEAS-SEMI (Grupo Enfermedades Autoinmune Sistémicas)-(Sociedad Española de Medicina Interna).</nlm:affiliation>
<wicri:noCountry code="subField">Spain; on behalf of GEAS-SEMI (Grupo Enfermedades Autoinmune Sistémicas)-(Sociedad Española de Medicina Interna)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Gonzalez Nieto, Jose Antonio" sort="Gonzalez Nieto, Jose Antonio" uniqKey="Gonzalez Nieto J" first="Jose Antonio" last="Gonzalez Nieto">Jose Antonio Gonzalez Nieto</name>
<affiliation><nlm:affiliation>Hospital Can Misses, Autoimmune Disease Unit, Internal Medicine, Ibiza, Spain; on behalf of GEAS-SEMI (Grupo Enfermedades Autoinmune Sistémicas)-(Sociedad Española de Medicina Interna).</nlm:affiliation>
<wicri:noCountry code="subField">Spain; on behalf of GEAS-SEMI (Grupo Enfermedades Autoinmune Sistémicas)-(Sociedad Española de Medicina Interna)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Guiducci, Serena" sort="Guiducci, Serena" uniqKey="Guiducci S" first="Serena" last="Guiducci">Serena Guiducci</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Clinical and Experimental Medicine, AOUC, University of Florence, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Clinical and Experimental Medicine, AOUC, University of Florence</wicri:regionArea>
<wicri:noRegion>University of Florence</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Jordan, Suzana" sort="Jordan, Suzana" uniqKey="Jordan S" first="Suzana" last="Jordan">Suzana Jordan</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Rheumatology, University Hospital Zurich, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Rheumatology, University Hospital Zurich</wicri:regionArea>
<wicri:noRegion>University Hospital Zurich</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Limaye, Vidya" sort="Limaye, Vidya" uniqKey="Limaye V" first="Vidya" last="Limaye">Vidya Limaye</name>
<affiliation wicri:level="1"><nlm:affiliation>Royal Adelaide Hospital, University of Adelaide, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Royal Adelaide Hospital, University of Adelaide</wicri:regionArea>
<wicri:noRegion>University of Adelaide</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Maurer, Britta" sort="Maurer, Britta" uniqKey="Maurer B" first="Britta" last="Maurer">Britta Maurer</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Rheumatology, University Hospital Zurich, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Rheumatology, University Hospital Zurich</wicri:regionArea>
<wicri:noRegion>University Hospital Zurich</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Selva O Callaghan, Albert" sort="Selva O Callaghan, Albert" uniqKey="Selva O Callaghan A" first="Albert" last="Selva-O'Callaghan">Albert Selva-O'Callaghan</name>
<affiliation><nlm:affiliation>Vall D'Hebron General Hospital, Autonoma Univeristy of Barcelona, Internal Medicine, Barcelona, Spain; on behalf of GEAS-SEMI (Grupo Enfermedades Autoinmune Sistémicas)-(Sociedad Española de Medicina Interna).</nlm:affiliation>
<wicri:noCountry code="subField">Spain; on behalf of GEAS-SEMI (Grupo Enfermedades Autoinmune Sistémicas)-(Sociedad Española de Medicina Interna)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Riccieri, Valeria" sort="Riccieri, Valeria" uniqKey="Riccieri V" first="Valeria" last="Riccieri">Valeria Riccieri</name>
<affiliation wicri:level="3"><nlm:affiliation>Sapienza University of Rome, Department of Internal Medicine and Medical Specialities, Rome, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Sapienza University of Rome, Department of Internal Medicine and Medical Specialities, Rome</wicri:regionArea>
<placeName><settlement type="city">Rome</settlement>
<region nuts="2">Latium</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Distler, Oliver" sort="Distler, Oliver" uniqKey="Distler O" first="Oliver" last="Distler">Oliver Distler</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Rheumatology, University Hospital Zurich, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Rheumatology, University Hospital Zurich</wicri:regionArea>
<wicri:noRegion>University Hospital Zurich</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Matucci Cerinic, Marco" sort="Matucci Cerinic, Marco" uniqKey="Matucci Cerinic M" first="Marco" last="Matucci-Cerinic">Marco Matucci-Cerinic</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Clinical and Experimental Medicine, AOUC, University of Florence, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Clinical and Experimental Medicine, AOUC, University of Florence</wicri:regionArea>
<wicri:noRegion>University of Florence</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Allanore, Yannick" sort="Allanore, Yannick" uniqKey="Allanore Y" first="Yannick" last="Allanore">Yannick Allanore</name>
<affiliation wicri:level="3"><nlm:affiliation>Paris Descartes University, Rheumatology A Department, APHP, Cochin Hospital, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Paris Descartes University, Rheumatology A Department, APHP, Cochin Hospital, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">Clinical and experimental rheumatology</title>
<idno type="ISSN">0392-856X</idno>
</series>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Connective Tissue Diseases (complications)</term>
<term>Connective Tissue Diseases (diagnosis)</term>
<term>Connective Tissue Diseases (drug therapy)</term>
<term>Disease Progression</term>
<term>Female</term>
<term>Humans</term>
<term>Immunosuppressive Agents (adverse effects)</term>
<term>Immunosuppressive Agents (therapeutic use)</term>
<term>Lung (drug effects)</term>
<term>Lung (physiopathology)</term>
<term>Lung Diseases, Interstitial (diagnosis)</term>
<term>Lung Diseases, Interstitial (drug therapy)</term>
<term>Lung Diseases, Interstitial (etiology)</term>
<term>Lung Diseases, Interstitial (physiopathology)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Recovery of Function</term>
<term>Respiratory Function Tests</term>
<term>Retrospective Studies</term>
<term>Rituximab (adverse effects)</term>
<term>Rituximab (therapeutic use)</term>
<term>Time Factors</term>
<term>Treatment Outcome</term>
<term>Vital Capacity</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Capacité vitale</term>
<term>Facteurs temps</term>
<term>Femelle</term>
<term>Humains</term>
<term>Immunosuppresseurs (effets indésirables)</term>
<term>Immunosuppresseurs (usage thérapeutique)</term>
<term>Maladies du tissu conjonctif ()</term>
<term>Maladies du tissu conjonctif (diagnostic)</term>
<term>Maladies du tissu conjonctif (traitement médicamenteux)</term>
<term>Mâle</term>
<term>Pneumopathies interstitielles (diagnostic)</term>
<term>Pneumopathies interstitielles (physiopathologie)</term>
<term>Pneumopathies interstitielles (traitement médicamenteux)</term>
<term>Pneumopathies interstitielles (étiologie)</term>
<term>Poumon ()</term>
<term>Poumon (physiopathologie)</term>
<term>Rituximab (effets indésirables)</term>
<term>Rituximab (usage thérapeutique)</term>
<term>Récupération fonctionnelle</term>
<term>Résultat thérapeutique</term>
<term>Sujet âgé</term>
<term>Tests de la fonction respiratoire</term>
<term>Études rétrospectives</term>
<term>Évolution de la maladie</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Immunosuppressive Agents</term>
<term>Rituximab</term>
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</keywords>
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<term>Lung Diseases, Interstitial</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Maladies du tissu conjonctif</term>
<term>Pneumopathies interstitielles</term>
</keywords>
<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Lung</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Connective Tissue Diseases</term>
<term>Lung Diseases, Interstitial</term>
</keywords>
<keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Immunosuppresseurs</term>
<term>Rituximab</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Lung Diseases, Interstitial</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Pneumopathies interstitielles</term>
<term>Poumon</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Lung</term>
<term>Lung Diseases, Interstitial</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Immunosuppressive Agents</term>
<term>Rituximab</term>
</keywords>
<keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Maladies du tissu conjonctif</term>
<term>Pneumopathies interstitielles</term>
</keywords>
<keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Immunosuppresseurs</term>
<term>Rituximab</term>
</keywords>
<keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Pneumopathies interstitielles</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Disease Progression</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Recovery of Function</term>
<term>Respiratory Function Tests</term>
<term>Retrospective Studies</term>
<term>Time Factors</term>
<term>Treatment Outcome</term>
<term>Vital Capacity</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Capacité vitale</term>
<term>Facteurs temps</term>
<term>Femelle</term>
<term>Humains</term>
<term>Maladies du tissu conjonctif</term>
<term>Mâle</term>
<term>Poumon</term>
<term>Récupération fonctionnelle</term>
<term>Résultat thérapeutique</term>
<term>Sujet âgé</term>
<term>Tests de la fonction respiratoire</term>
<term>Études rétrospectives</term>
<term>Évolution de la maladie</term>
</keywords>
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<front><div type="abstract" xml:lang="en">Interstitial lung disease (ILD) is a key prognostic factor in connective tissue disorders (CTDs). The aim of our study was to assess the changes in pulmonary functional tests (PFTs) in various CTDs, including anti-synthetase syndrome (SYN), systemic sclerosis (SSc) and mixed connective tissue disorder (MCTD), following the use of rituximab therapy.</div>
</front>
</TEI>
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