Role of cortical bone in bone fragility.
Identifieur interne : 002610 ( Ncbi/Curation ); précédent : 002609; suivant : 002611Role of cortical bone in bone fragility.
Auteurs : Yohann Bala [Australie] ; Roger Zebaze ; Ego SeemanSource :
- Current opinion in rheumatology [ 1531-6963 ] ; 2015.
Descripteurs français
- KwdFr :
- MESH :
- physiologie : Densité osseuse, Remodelage osseux.
- physiopathologie : Fractures ostéoporotiques, Ostéoporose.
- Humains, Porosité.
English descriptors
- KwdEn :
- MESH :
- physiology : Bone Density, Bone Remodeling.
- physiopathology : Osteoporosis, Osteoporotic Fractures.
- Humans, Porosity.
Abstract
Trabecular bone loss and vertebral fractures are historical hallmarks of osteoporosis. During the past 70 years, this view has dominated research aiming to understand the structural basis of bone fragility. We suggest this notion needs to be revised to recognize and include the role of cortical bone deterioration as an important determinant of bone strength throughout life.
DOI: 10.1097/BOR.0000000000000183
PubMed: 26002033
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