High-intensity statin therapy alters the natural history of diabetic coronary atherosclerosis: insights from SATURN.
Identifieur interne : 001D73 ( Ncbi/Curation ); précédent : 001D72; suivant : 001D74High-intensity statin therapy alters the natural history of diabetic coronary atherosclerosis: insights from SATURN.
Auteurs : Brian Stegman [États-Unis] ; Rishi Puri [États-Unis] ; Leslie Cho [États-Unis] ; Mingyuan Shao [États-Unis] ; Christie M. Ballantyne [États-Unis] ; Phillip J. Barter [Australie] ; M John Chapman [France] ; Raimund Erbel [Allemagne] ; Peter Libby [États-Unis] ; Joel S. Raichlen [États-Unis] ; Kiyoko Uno [États-Unis] ; Yu Kataoka [Australie] ; Steven E. Nissen [États-Unis] ; Stephen J. Nicholls [Oman]Source :
- Diabetes care [ 1935-5548 ] ; 2014.
Descripteurs français
- KwdFr :
- Acides heptanoïques (usage thérapeutique), Adulte d'âge moyen, Atorvastatine de calcium, Cholestérol HDL (sang), Cholestérol LDL (sang), Diabète (traitement médicamenteux), Femelle, Fluorobenzènes (usage thérapeutique), Humains, Inhibiteurs de l'hydroxyméthylglutaryl-CoA réductase (usage thérapeutique), Maladie des artères coronaires (traitement médicamenteux), Mâle, Plaque d'athérosclérose (traitement médicamenteux), Plaque d'athérosclérose (étiologie), Pyrimidines (usage thérapeutique), Pyrroles (usage thérapeutique), Rosuvastatine de calcium, Sujet âgé, Sulfonamides (usage thérapeutique), Échographie interventionnelle.
- MESH :
- sang : Cholestérol HDL, Cholestérol LDL.
- traitement médicamenteux : Diabète, Maladie des artères coronaires, Plaque d'athérosclérose.
- usage thérapeutique : Acides heptanoïques, Fluorobenzènes, Inhibiteurs de l'hydroxyméthylglutaryl-CoA réductase, Pyrimidines, Pyrroles, Sulfonamides.
- étiologie : Plaque d'athérosclérose.
- Adulte d'âge moyen, Atorvastatine de calcium, Femelle, Humains, Mâle, Rosuvastatine de calcium, Sujet âgé, Échographie interventionnelle.
English descriptors
- KwdEn :
- Aged, Atorvastatin Calcium, Cholesterol, HDL (blood), Cholesterol, LDL (blood), Coronary Artery Disease (drug therapy), Diabetes Mellitus (drug therapy), Female, Fluorobenzenes (therapeutic use), Heptanoic Acids (therapeutic use), Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors (therapeutic use), Male, Middle Aged, Plaque, Atherosclerotic (drug therapy), Plaque, Atherosclerotic (etiology), Pyrimidines (therapeutic use), Pyrroles (therapeutic use), Rosuvastatin Calcium, Sulfonamides (therapeutic use), Ultrasonography, Interventional.
- MESH :
- chemical , blood : Cholesterol, HDL, Cholesterol, LDL.
- chemical , therapeutic use : Fluorobenzenes, Heptanoic Acids, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Pyrimidines, Pyrroles, Sulfonamides.
- chemical : Atorvastatin Calcium, Rosuvastatin Calcium.
- drug therapy : Coronary Artery Disease, Diabetes Mellitus, Plaque, Atherosclerotic.
- etiology : Plaque, Atherosclerotic.
- Aged, Female, Humans, Male, Middle Aged, Ultrasonography, Interventional.
Abstract
Although statins can induce coronary atheroma regression, this benefit has yet to be demonstrated in diabetic individuals. We tested the hypothesis that high-intensity statin therapy may promote coronary atheroma regression in patients with diabetes.
DOI: 10.2337/dc14-1121
PubMed: 25190674
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Ballantyne</name><affiliation wicri:level="2"><nlm:affiliation>Section of Cardiovascular Research, Baylor College of Medicine, and the Methodist DeBakey Heart and Vascular Center, Houston, TX.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Texas</region></placeName><wicri:cityArea>Section of Cardiovascular Research, Baylor College of Medicine, and the Methodist DeBakey Heart and Vascular Center, Houston</wicri:cityArea></affiliation></author><author><name sortKey="Barter, Phillip J" sort="Barter, Phillip J" uniqKey="Barter P" first="Phillip J" last="Barter">Phillip J. Barter</name><affiliation wicri:level="3"><nlm:affiliation>Centre for Vascular Research, University of New South Wales, Sydney, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Vascular Research, University of New South Wales, Sydney</wicri:regionArea><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation></author><author><name sortKey="Chapman, M John" sort="Chapman, M John" uniqKey="Chapman M" first="M John" last="Chapman">M John Chapman</name><affiliation wicri:level="3"><nlm:affiliation>INSERM Dyslipidaemia and Atherosclerosis Research Unit, Pitié-Salpètrière University Hospital, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM Dyslipidaemia and Atherosclerosis Research Unit, Pitié-Salpètrière University Hospital, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Erbel, Raimund" sort="Erbel, Raimund" uniqKey="Erbel R" first="Raimund" last="Erbel">Raimund Erbel</name><affiliation wicri:level="1"><nlm:affiliation>West German Heart Center, Essen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>West German Heart Center, Essen</wicri:regionArea><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Libby, Peter" sort="Libby, Peter" uniqKey="Libby P" first="Peter" last="Libby">Peter Libby</name><affiliation wicri:level="2"><nlm:affiliation>Cardiovascular Division, Brigham and Women's Hospital, Boston, MA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Cardiovascular Division, Brigham and Women's Hospital, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Raichlen, Joel S" sort="Raichlen, Joel S" uniqKey="Raichlen J" first="Joel S" last="Raichlen">Joel S. Raichlen</name><affiliation wicri:level="2"><nlm:affiliation>AstraZeneca, Wilmington, DE.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Delaware</region></placeName><wicri:cityArea>AstraZeneca, Wilmington</wicri:cityArea></affiliation></author><author><name sortKey="Uno, Kiyoko" sort="Uno, Kiyoko" uniqKey="Uno K" first="Kiyoko" last="Uno">Kiyoko Uno</name><affiliation wicri:level="2"><nlm:affiliation>Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea>Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland</wicri:cityArea></affiliation></author><author><name sortKey="Kataoka, Yu" sort="Kataoka, Yu" uniqKey="Kataoka Y" first="Yu" last="Kataoka">Yu Kataoka</name><affiliation wicri:level="1"><nlm:affiliation>South Australian Health and Medical Research Institute, University of Adelaide, Adelaide, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>South Australian Health and Medical Research Institute, University of Adelaide, Adelaide</wicri:regionArea><wicri:noRegion>Adelaide</wicri:noRegion></affiliation></author><author><name sortKey="Nissen, Steven E" sort="Nissen, Steven E" uniqKey="Nissen S" first="Steven E" last="Nissen">Steven E. Nissen</name><affiliation wicri:level="2"><nlm:affiliation>Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH C5Research, Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea>Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH C5Research, Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland</wicri:cityArea></affiliation></author><author><name sortKey="Nicholls, Stephen J" sort="Nicholls, Stephen J" uniqKey="Nicholls S" first="Stephen J" last="Nicholls">Stephen J. Nicholls</name><affiliation wicri:level="1"><nlm:affiliation>South Australian Health and Medical Research Institute, University of Adelaide, Adelaide, Australia stephen.nicholls@sahmri.com.</nlm:affiliation><country wicri:rule="url">Oman</country><wicri:regionArea>South Australian Health and Medical Research Institute, University of Adelaide, Adelaide</wicri:regionArea><wicri:noRegion>Adelaide</wicri:noRegion></affiliation></author></analytic><series><title level="j">Diabetes care</title><idno type="eISSN">1935-5548</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Atorvastatin Calcium</term><term>Cholesterol, HDL (blood)</term><term>Cholesterol, LDL (blood)</term><term>Coronary Artery Disease (drug therapy)</term><term>Diabetes Mellitus (drug therapy)</term><term>Female</term><term>Fluorobenzenes (therapeutic use)</term><term>Heptanoic Acids (therapeutic use)</term><term>Humans</term><term>Hydroxymethylglutaryl-CoA Reductase Inhibitors (therapeutic use)</term><term>Male</term><term>Middle Aged</term><term>Plaque, Atherosclerotic (drug therapy)</term><term>Plaque, Atherosclerotic (etiology)</term><term>Pyrimidines (therapeutic use)</term><term>Pyrroles (therapeutic use)</term><term>Rosuvastatin Calcium</term><term>Sulfonamides (therapeutic use)</term><term>Ultrasonography, Interventional</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Acides heptanoïques (usage thérapeutique)</term><term>Adulte d'âge moyen</term><term>Atorvastatine de calcium</term><term>Cholestérol HDL (sang)</term><term>Cholestérol LDL (sang)</term><term>Diabète (traitement médicamenteux)</term><term>Femelle</term><term>Fluorobenzènes (usage thérapeutique)</term><term>Humains</term><term>Inhibiteurs de l'hydroxyméthylglutaryl-CoA réductase (usage thérapeutique)</term><term>Maladie des artères coronaires (traitement médicamenteux)</term><term>Mâle</term><term>Plaque d'athérosclérose (traitement médicamenteux)</term><term>Plaque d'athérosclérose (étiologie)</term><term>Pyrimidines (usage thérapeutique)</term><term>Pyrroles (usage thérapeutique)</term><term>Rosuvastatine de calcium</term><term>Sujet âgé</term><term>Sulfonamides (usage thérapeutique)</term><term>Échographie interventionnelle</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Cholesterol, HDL</term><term>Cholesterol, LDL</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Fluorobenzenes</term><term>Heptanoic Acids</term><term>Hydroxymethylglutaryl-CoA Reductase Inhibitors</term><term>Pyrimidines</term><term>Pyrroles</term><term>Sulfonamides</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>Atorvastatin Calcium</term><term>Rosuvastatin Calcium</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Coronary Artery Disease</term><term>Diabetes Mellitus</term><term>Plaque, Atherosclerotic</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Plaque, Atherosclerotic</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Cholestérol HDL</term><term>Cholestérol LDL</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Diabète</term><term>Maladie des artères coronaires</term><term>Plaque d'athérosclérose</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Acides heptanoïques</term><term>Fluorobenzènes</term><term>Inhibiteurs de l'hydroxyméthylglutaryl-CoA réductase</term><term>Pyrimidines</term><term>Pyrroles</term><term>Sulfonamides</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Plaque d'athérosclérose</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Ultrasonography, Interventional</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Atorvastatine de calcium</term><term>Femelle</term><term>Humains</term><term>Mâle</term><term>Rosuvastatine de calcium</term><term>Sujet âgé</term><term>Échographie interventionnelle</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Although statins can induce coronary atheroma regression, this benefit has yet to be demonstrated in diabetic individuals. We tested the hypothesis that high-intensity statin therapy may promote coronary atheroma regression in patients with diabetes.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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