Immunotherapy of distant metastatic disease
Identifieur interne : 000616 ( Ncbi/Curation ); précédent : 000615; suivant : 000617Immunotherapy of distant metastatic disease
Auteurs : D. Schadendorf [Allemagne] ; S. M. Algarra [Espagne] ; L. Bastholt [Danemark] ; G. Cinat [Argentine] ; B. Dreno [France] ; A. M. M. Eggermont [Pays-Bas] ; E. Espinosa [Espagne] ; J. Guo [République populaire de Chine] ; A. Hauschild [Allemagne] ; T. Petrella [Canada] ; J. Schachter [Israël] ; P. Hersey [Australie]Source :
- Annals of Oncology [ 0923-7534 ] ; 2009.
Abstract
Immunotherapy of metastatic melanoma consists of various approaches leading to specific or non-specific immunomodulation. The use of FDA-approved interleukin (IL)-2 alone, in combination with interferon α, and/or with various chemotherapeutic agents (biochemotherapy) is associated with significant toxicity and poor efficacy that does not improve overall survival of 96% of patients. Many studies with allogeneic and autologous vaccines have demonstrated no clinical benefit, and some randomised trials even showed a detrimental effect in the vaccine arm. The ongoing effort to develop melanoma vaccines based on dendritic cells and peptides is driven by advances in understanding antigen presentation and processing, and by new techniques of vaccine preparation, stabilisation and delivery. Several agents that have shown promising activity in metastatic melanoma including IL-21 and monoclonal antibodies targeting cytotoxic T lymphocyte-associated antigen 4 (anti-CTLA-4) or CD137 are discussed. Recent advances of intratumour gene transfer technologies and adoptive immunotherapy, which represents a promising although technically challenging direction, are also discussed.
Url:
DOI: 10.1093/annonc/mdp253
PubMed: 19617297
PubMed Central: 2712591
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PMC:2712591Le document en format XML
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Algarra</name><affiliation wicri:level="1"><nlm:aff id="aff2">Department of Oncology, Clinica Universitaria de Navarra, Pamplona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Oncology, Clinica Universitaria de Navarra, Pamplona</wicri:regionArea><wicri:noRegion>Pamplona</wicri:noRegion></affiliation></author><author><name sortKey="Bastholt, L" sort="Bastholt, L" uniqKey="Bastholt L" first="L." last="Bastholt">L. Bastholt</name><affiliation wicri:level="1"><nlm:aff id="aff3">Department of Oncology, Odense University Hospital, Odense, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Oncology, Odense University Hospital, Odense</wicri:regionArea><wicri:noRegion>Odense</wicri:noRegion></affiliation></author><author><name sortKey="Cinat, G" sort="Cinat, G" uniqKey="Cinat G" first="G." last="Cinat">G. Cinat</name><affiliation wicri:level="1"><nlm:aff id="aff4">Department of Oncology, Instituto de Oncologia Angel Roffo, Buenos Aires, Argentina</nlm:aff><country xml:lang="fr">Argentine</country><wicri:regionArea>Department of Oncology, Instituto de Oncologia Angel Roffo, Buenos Aires</wicri:regionArea><wicri:noRegion>Buenos Aires</wicri:noRegion></affiliation></author><author><name sortKey="Dreno, B" sort="Dreno, B" uniqKey="Dreno B" first="B." last="Dreno">B. Dreno</name><affiliation wicri:level="1"><nlm:aff id="aff5">Clinique of Dermatologie, Hôtel Dieu, Nantes Cedex 01, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Clinique of Dermatologie, Hôtel Dieu, Nantes Cedex 01</wicri:regionArea><wicri:noRegion>Nantes Cedex 01</wicri:noRegion><wicri:noRegion>Nantes Cedex 01</wicri:noRegion></affiliation></author><author><name sortKey="Eggermont, A M M" sort="Eggermont, A M M" uniqKey="Eggermont A" first="A. M. M." last="Eggermont">A. M. M. Eggermont</name><affiliation wicri:level="3"><nlm:aff id="aff6">Department of Surgical Oncology, Erasmus University Medical Center–Daniel den Hoed Cancer Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Surgical Oncology, Erasmus University Medical Center–Daniel den Hoed Cancer Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Espinosa, E" sort="Espinosa, E" uniqKey="Espinosa E" first="E." last="Espinosa">E. Espinosa</name><affiliation wicri:level="3"><nlm:aff id="aff7">Department of Oncology, Hospital La Paz, Madrid, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Oncology, Hospital La Paz, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Guo, J" sort="Guo, J" uniqKey="Guo J" first="J." last="Guo">J. Guo</name><affiliation wicri:level="3"><nlm:aff id="aff8">Department of Oncology, Peking University School of Oncology, Beijing, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Oncology, Peking University School of Oncology, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Hauschild, A" sort="Hauschild, A" uniqKey="Hauschild A" first="A." last="Hauschild">A. Hauschild</name><affiliation wicri:level="3"><nlm:aff id="aff9">Department of Dermatology, University of Kiel, Kiel, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology, University of Kiel, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author><author><name sortKey="Petrella, T" sort="Petrella, T" uniqKey="Petrella T" first="T." last="Petrella">T. Petrella</name><affiliation wicri:level="1"><nlm:aff id="aff10">Toronto Sunnybrook Regional Cancer Center, Toronto, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Toronto Sunnybrook Regional Cancer Center, Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Schachter, J" sort="Schachter, J" uniqKey="Schachter J" first="J." last="Schachter">J. Schachter</name><affiliation wicri:level="1"><nlm:aff id="aff11">The Ella Institute for Treatment and Research of Melanoma, Tel Hashomer, Israel</nlm:aff><country xml:lang="fr">Israël</country><wicri:regionArea>The Ella Institute for Treatment and Research of Melanoma, Tel Hashomer</wicri:regionArea><wicri:noRegion>Tel Hashomer</wicri:noRegion></affiliation></author><author><name sortKey="Hersey, P" sort="Hersey, P" uniqKey="Hersey P" first="P." last="Hersey">P. Hersey</name><affiliation wicri:level="1"><nlm:aff id="aff12">Immunology and Oncology Unit, Calvary Mater Newcastle Hospital, New South Wales, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Immunology and Oncology Unit, Calvary Mater Newcastle Hospital, New South Wales</wicri:regionArea><wicri:noRegion>New South Wales</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">19617297</idno><idno type="pmc">2712591</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712591</idno><idno type="RBID">PMC:2712591</idno><idno type="doi">10.1093/annonc/mdp253</idno><date when="2009">2009</date><idno type="wicri:Area/Pmc/Corpus">002241</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002241</idno><idno type="wicri:Area/Pmc/Curation">002091</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002091</idno><idno type="wicri:Area/Pmc/Checkpoint">002783</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">002783</idno><idno type="wicri:Area/Ncbi/Merge">000616</idno><idno type="wicri:Area/Ncbi/Curation">000616</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Immunotherapy of distant metastatic disease</title><author><name sortKey="Schadendorf, D" sort="Schadendorf, D" uniqKey="Schadendorf D" first="D." last="Schadendorf">D. Schadendorf</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Dermatology, University Hospital Essen, Essen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology, University Hospital Essen, Essen</wicri:regionArea><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Algarra, S M" sort="Algarra, S M" uniqKey="Algarra S" first="S. M." last="Algarra">S. M. Algarra</name><affiliation wicri:level="1"><nlm:aff id="aff2">Department of Oncology, Clinica Universitaria de Navarra, Pamplona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Oncology, Clinica Universitaria de Navarra, Pamplona</wicri:regionArea><wicri:noRegion>Pamplona</wicri:noRegion></affiliation></author><author><name sortKey="Bastholt, L" sort="Bastholt, L" uniqKey="Bastholt L" first="L." last="Bastholt">L. Bastholt</name><affiliation wicri:level="1"><nlm:aff id="aff3">Department of Oncology, Odense University Hospital, Odense, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Oncology, Odense University Hospital, Odense</wicri:regionArea><wicri:noRegion>Odense</wicri:noRegion></affiliation></author><author><name sortKey="Cinat, G" sort="Cinat, G" uniqKey="Cinat G" first="G." last="Cinat">G. Cinat</name><affiliation wicri:level="1"><nlm:aff id="aff4">Department of Oncology, Instituto de Oncologia Angel Roffo, Buenos Aires, Argentina</nlm:aff><country xml:lang="fr">Argentine</country><wicri:regionArea>Department of Oncology, Instituto de Oncologia Angel Roffo, Buenos Aires</wicri:regionArea><wicri:noRegion>Buenos Aires</wicri:noRegion></affiliation></author><author><name sortKey="Dreno, B" sort="Dreno, B" uniqKey="Dreno B" first="B." last="Dreno">B. Dreno</name><affiliation wicri:level="1"><nlm:aff id="aff5">Clinique of Dermatologie, Hôtel Dieu, Nantes Cedex 01, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Clinique of Dermatologie, Hôtel Dieu, Nantes Cedex 01</wicri:regionArea><wicri:noRegion>Nantes Cedex 01</wicri:noRegion><wicri:noRegion>Nantes Cedex 01</wicri:noRegion></affiliation></author><author><name sortKey="Eggermont, A M M" sort="Eggermont, A M M" uniqKey="Eggermont A" first="A. M. M." last="Eggermont">A. M. M. Eggermont</name><affiliation wicri:level="3"><nlm:aff id="aff6">Department of Surgical Oncology, Erasmus University Medical Center–Daniel den Hoed Cancer Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Surgical Oncology, Erasmus University Medical Center–Daniel den Hoed Cancer Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Espinosa, E" sort="Espinosa, E" uniqKey="Espinosa E" first="E." last="Espinosa">E. Espinosa</name><affiliation wicri:level="3"><nlm:aff id="aff7">Department of Oncology, Hospital La Paz, Madrid, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Oncology, Hospital La Paz, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Guo, J" sort="Guo, J" uniqKey="Guo J" first="J." last="Guo">J. Guo</name><affiliation wicri:level="3"><nlm:aff id="aff8">Department of Oncology, Peking University School of Oncology, Beijing, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Oncology, Peking University School of Oncology, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Hauschild, A" sort="Hauschild, A" uniqKey="Hauschild A" first="A." last="Hauschild">A. Hauschild</name><affiliation wicri:level="3"><nlm:aff id="aff9">Department of Dermatology, University of Kiel, Kiel, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology, University of Kiel, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author><author><name sortKey="Petrella, T" sort="Petrella, T" uniqKey="Petrella T" first="T." last="Petrella">T. Petrella</name><affiliation wicri:level="1"><nlm:aff id="aff10">Toronto Sunnybrook Regional Cancer Center, Toronto, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Toronto Sunnybrook Regional Cancer Center, Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Schachter, J" sort="Schachter, J" uniqKey="Schachter J" first="J." last="Schachter">J. Schachter</name><affiliation wicri:level="1"><nlm:aff id="aff11">The Ella Institute for Treatment and Research of Melanoma, Tel Hashomer, Israel</nlm:aff><country xml:lang="fr">Israël</country><wicri:regionArea>The Ella Institute for Treatment and Research of Melanoma, Tel Hashomer</wicri:regionArea><wicri:noRegion>Tel Hashomer</wicri:noRegion></affiliation></author><author><name sortKey="Hersey, P" sort="Hersey, P" uniqKey="Hersey P" first="P." last="Hersey">P. Hersey</name><affiliation wicri:level="1"><nlm:aff id="aff12">Immunology and Oncology Unit, Calvary Mater Newcastle Hospital, New South Wales, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Immunology and Oncology Unit, Calvary Mater Newcastle Hospital, New South Wales</wicri:regionArea><wicri:noRegion>New South Wales</wicri:noRegion></affiliation></author></analytic><series><title level="j">Annals of Oncology</title><idno type="ISSN">0923-7534</idno><idno type="eISSN">1569-8041</idno><imprint><date when="2009">2009</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Immunotherapy of metastatic melanoma consists of various approaches leading to specific or non-specific immunomodulation. The use of FDA-approved interleukin (IL)-2 alone, in combination with interferon α, and/or with various chemotherapeutic agents (biochemotherapy) is associated with significant toxicity and poor efficacy that does not improve overall survival of 96% of patients. Many studies with allogeneic and autologous vaccines have demonstrated no clinical benefit, and some randomised trials even showed a detrimental effect in the vaccine arm. The ongoing effort to develop melanoma vaccines based on dendritic cells and peptides is driven by advances in understanding antigen presentation and processing, and by new techniques of vaccine preparation, stabilisation and delivery. Several agents that have shown promising activity in metastatic melanoma including IL-21 and monoclonal antibodies targeting cytotoxic T lymphocyte-associated antigen 4 (anti-CTLA-4) or CD137 are discussed. Recent advances of intratumour gene transfer technologies and adoptive immunotherapy, which represents a promising although technically challenging direction, are also discussed.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Balch, Cm" uniqKey="Balch C">CM Balch</name></author><author><name sortKey="Buzaid, Ac" uniqKey="Buzaid A">AC Buzaid</name></author><author><name sortKey="Soong, Sj" uniqKey="Soong S">SJ Soong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Atkins, Mb" uniqKey="Atkins M">MB Atkins</name></author><author><name sortKey="Lotze, Mt" uniqKey="Lotze M">MT Lotze</name></author><author><name sortKey="Dutcher, Jp" uniqKey="Dutcher J">JP Dutcher</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tsao, H" uniqKey="Tsao H">H Tsao</name></author><author><name sortKey="Atkins, Mb" uniqKey="Atkins M">MB Atkins</name></author><author><name sortKey="Sober, Aj" uniqKey="Sober A">AJ Sober</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Keilholz, U" uniqKey="Keilholz U">U Keilholz</name></author><author><name sortKey="Conradt, C" uniqKey="Conradt C">C Conradt</name></author><author><name sortKey="Legha, Ss" uniqKey="Legha S">SS Legha</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Phan, Gq" uniqKey="Phan G">GQ Phan</name></author><author><name sortKey="Attia, P" uniqKey="Attia P">P Attia</name></author><author><name sortKey="Steinberg, Sm" uniqKey="Steinberg S">SM Steinberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schmidt, H" uniqKey="Schmidt H">H Schmidt</name></author><author><name sortKey="Bastholt, L" uniqKey="Bastholt L">L Bastholt</name></author><author><name sortKey="Geertsen, P" uniqKey="Geertsen P">P Geertsen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schmidt, H" uniqKey="Schmidt H">H Schmidt</name></author><author><name sortKey="Suciu, S" uniqKey="Suciu S">S Suciu</name></author><author><name sortKey="Punt, Cj" uniqKey="Punt C">CJ Punt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tarhini, Aa" uniqKey="Tarhini A">AA Tarhini</name></author><author><name sortKey="Kirkwood, Jm" uniqKey="Kirkwood J">JM Kirkwood</name></author><author><name sortKey="Gooding, We" uniqKey="Gooding W">WE Gooding</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Petrella, T" uniqKey="Petrella T">T Petrella</name></author><author><name sortKey="Quirt, I" uniqKey="Quirt I">I Quirt</name></author><author><name sortKey="Verma, S" uniqKey="Verma S">S Verma</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Legha, Ss" uniqKey="Legha S">SS Legha</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bukowski, Rm" uniqKey="Bukowski R">RM Bukowski</name></author><author><name sortKey="Tendler, C" uniqKey="Tendler C">C Tendler</name></author><author><name sortKey="Cutler, D" uniqKey="Cutler D">D Cutler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dummer, R" uniqKey="Dummer R">R Dummer</name></author><author><name sortKey="Garbe, C" uniqKey="Garbe C">C Garbe</name></author><author><name sortKey="Thompson, Ja" uniqKey="Thompson J">JA Thompson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hauschild, A" uniqKey="Hauschild A">A Hauschild</name></author><author><name sortKey="Dummer, R" uniqKey="Dummer R">R Dummer</name></author><author><name sortKey="Ugurel, S" uniqKey="Ugurel S">S Ugurel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Spieth, K" uniqKey="Spieth K">K Spieth</name></author><author><name sortKey="Kaufmann, R" uniqKey="Kaufmann R">R Kaufmann</name></author><author><name sortKey="Dummer, R" uniqKey="Dummer R">R Dummer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sparano, Ja" uniqKey="Sparano J">JA Sparano</name></author><author><name sortKey="Fisher, Ri" uniqKey="Fisher R">RI Fisher</name></author><author><name sortKey="Sunderland, M" uniqKey="Sunderland M">M Sunderland</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Marincola, Fm" uniqKey="Marincola F">FM Marincola</name></author><author><name sortKey="White, De" uniqKey="White D">DE White</name></author><author><name sortKey="Wise, Ap" uniqKey="Wise A">AP Wise</name></author><author><name sortKey="Rosenberg, Sa" uniqKey="Rosenberg S">SA Rosenberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hamm, C" uniqKey="Hamm C">C Hamm</name></author><author><name sortKey="Verma, S" uniqKey="Verma S">S Verma</name></author><author><name sortKey="Petrella, T" uniqKey="Petrella T">T Petrella</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ives, Nj" uniqKey="Ives N">NJ Ives</name></author><author><name sortKey="Stowe, Rl" uniqKey="Stowe R">RL Stowe</name></author><author><name sortKey="Lorigan, P" uniqKey="Lorigan P">P Lorigan</name></author><author><name sortKey="Wheatley, K" uniqKey="Wheatley K">K Wheatley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Falkson, Ci" uniqKey="Falkson C">CI Falkson</name></author><author><name sortKey="Falkson, G" uniqKey="Falkson G">G Falkson</name></author><author><name sortKey="Falkson, Hc" uniqKey="Falkson H">HC Falkson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thomson, Db" uniqKey="Thomson D">DB Thomson</name></author><author><name sortKey="Adena, M" uniqKey="Adena M">M Adena</name></author><author><name sortKey="Mcleod, Gr" uniqKey="Mcleod G">GR McLeod</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bajetta, E" uniqKey="Bajetta E">E Bajetta</name></author><author><name sortKey="Di Leo, A" uniqKey="Di Leo A">A Di Leo</name></author><author><name sortKey="Zampino, Mg" uniqKey="Zampino M">MG Zampino</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Falkson, Ci" uniqKey="Falkson C">CI Falkson</name></author><author><name sortKey="Ibrahim, J" uniqKey="Ibrahim J">J Ibrahim</name></author><author><name sortKey="Kirkwood, Jm" uniqKey="Kirkwood J">JM Kirkwood</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Middleton, Mr" uniqKey="Middleton M">MR Middleton</name></author><author><name sortKey="Lorigan, P" uniqKey="Lorigan P">P Lorigan</name></author><author><name sortKey="Owen, J" uniqKey="Owen J">J Owen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Young, Am" uniqKey="Young A">AM Young</name></author><author><name sortKey="Marsden, J" uniqKey="Marsden J">J Marsden</name></author><author><name sortKey="Goodman, A" uniqKey="Goodman A">A Goodman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kaufmann, R" uniqKey="Kaufmann R">R Kaufmann</name></author><author><name sortKey="Spieth, K" uniqKey="Spieth K">K Spieth</name></author><author><name sortKey="Leiter, U" uniqKey="Leiter U">U Leiter</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vuoristo, Ms" uniqKey="Vuoristo M">MS Vuoristo</name></author><author><name sortKey="Hahka Kemppinen, M" uniqKey="Hahka Kemppinen M">M Hahka-Kemppinen</name></author><author><name sortKey="Parvinen, Lm" uniqKey="Parvinen L">LM Parvinen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Agarwala, Ss" uniqKey="Agarwala S">SS Agarwala</name></author><author><name sortKey="Glaspy, J" uniqKey="Glaspy J">J Glaspy</name></author><author><name sortKey="O Day, Sj" uniqKey="O Day S">SJ O'Day</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Keilholz, U" uniqKey="Keilholz U">U Keilholz</name></author><author><name sortKey="Goey, Sh" uniqKey="Goey S">SH Goey</name></author><author><name sortKey="Punt, Cj" uniqKey="Punt C">CJ Punt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Johnston, Sr" uniqKey="Johnston S">SR Johnston</name></author><author><name sortKey="Constenla, Do" uniqKey="Constenla D">DO Constenla</name></author><author><name sortKey="Moore, J" uniqKey="Moore J">J Moore</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dorval, T" uniqKey="Dorval T">T Dorval</name></author><author><name sortKey="Negrier, S" uniqKey="Negrier S">S Negrier</name></author><author><name sortKey="Chevreau, C" uniqKey="Chevreau C">C Chevreau</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rosenberg, Sa" uniqKey="Rosenberg S">SA Rosenberg</name></author><author><name sortKey="Yang, Jc" uniqKey="Yang J">JC Yang</name></author><author><name sortKey="Schwartzentruber, Dj" uniqKey="Schwartzentruber D">DJ Schwartzentruber</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hauschild, A" uniqKey="Hauschild A">A Hauschild</name></author><author><name sortKey="Garbe, C" uniqKey="Garbe C">C Garbe</name></author><author><name sortKey="Stolz, W" uniqKey="Stolz W">W Stolz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Eton, O" uniqKey="Eton O">O Eton</name></author><author><name sortKey="Legha, Ss" uniqKey="Legha S">SS Legha</name></author><author><name sortKey="Bedikian, Ay" uniqKey="Bedikian A">AY Bedikian</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Atzpodien, J" uniqKey="Atzpodien J">J Atzpodien</name></author><author><name sortKey="Neuber, K" uniqKey="Neuber K">K Neuber</name></author><author><name sortKey="Kamanabrou, D" uniqKey="Kamanabrou D">D Kamanabrou</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ridolfi, R" uniqKey="Ridolfi R">R Ridolfi</name></author><author><name sortKey="Chiarion Sileni, V" uniqKey="Chiarion Sileni V">V Chiarion-Sileni</name></author><author><name sortKey="Guida, M" uniqKey="Guida M">M Guida</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Keilholz, U" uniqKey="Keilholz U">U Keilholz</name></author><author><name sortKey="Punt, Cj" uniqKey="Punt C">CJ Punt</name></author><author><name sortKey="Gore, M" uniqKey="Gore M">M Gore</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bajetta, E" uniqKey="Bajetta E">E Bajetta</name></author><author><name sortKey="Del Vecchio, M" uniqKey="Del Vecchio M">M Del Vecchio</name></author><author><name sortKey="Nova, P" uniqKey="Nova P">P Nova</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Atkins, Mb" uniqKey="Atkins M">MB Atkins</name></author><author><name sortKey="Hsu, J" uniqKey="Hsu J">J Hsu</name></author><author><name sortKey="Lee, S" uniqKey="Lee S">S Lee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Davis, Id" uniqKey="Davis I">ID Davis</name></author><author><name sortKey="Skak, K" uniqKey="Skak K">K Skak</name></author><author><name sortKey="Smyth, Mj" uniqKey="Smyth M">MJ Smyth</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fehniger, Ta" uniqKey="Fehniger T">TA Fehniger</name></author><author><name sortKey="Cooper, Ma" uniqKey="Cooper M">MA Cooper</name></author><author><name sortKey="Caligiuri, Ma" uniqKey="Caligiuri M">MA Caligiuri</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thompson, Ja" uniqKey="Thompson J">JA Thompson</name></author><author><name sortKey="Curti, Bd" uniqKey="Curti B">BD Curti</name></author><author><name sortKey="Redman, Bg" uniqKey="Redman B">BG Redman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Frederiksen, Ks" uniqKey="Frederiksen K">KS Frederiksen</name></author><author><name sortKey="Lundsgaard, D" uniqKey="Lundsgaard D">D Lundsgaard</name></author><author><name sortKey="Freeman, Ja" uniqKey="Freeman J">JA Freeman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Inman, Ba" uniqKey="Inman B">BA Inman</name></author><author><name sortKey="Frigola, X" uniqKey="Frigola X">X Frigola</name></author><author><name sortKey="Dong, H" uniqKey="Dong H">H Dong</name></author><author><name sortKey="Kwon, Ed" uniqKey="Kwon E">ED Kwon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Melero, I" uniqKey="Melero I">I Melero</name></author><author><name sortKey="Hervas Stubbs, S" uniqKey="Hervas Stubbs S">S Hervas-Stubbs</name></author><author><name sortKey="Glennie, M" uniqKey="Glennie M">M Glennie</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="O Day, Sj" uniqKey="O Day S">SJ O'Day</name></author><author><name sortKey="Hamid, O" uniqKey="Hamid O">O Hamid</name></author><author><name sortKey="Urba, Wj" uniqKey="Urba W">WJ Urba</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cranmer, Ld" uniqKey="Cranmer L">LD Cranmer</name></author><author><name sortKey="Hersh, E" uniqKey="Hersh E">E Hersh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Weber, J" uniqKey="Weber J">J Weber</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ribas, A" uniqKey="Ribas A">A Ribas</name></author><author><name sortKey="Hanson, Dc" uniqKey="Hanson D">DC Hanson</name></author><author><name sortKey="Noe, Da" uniqKey="Noe D">DA Noe</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hersh, Em" uniqKey="Hersh E">EM Hersh</name></author><author><name sortKey="Weber, Js" uniqKey="Weber J">JS Weber</name></author><author><name sortKey="Powderly, Jd" uniqKey="Powderly J">JD Powderly</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Attia, P" uniqKey="Attia P">P Attia</name></author><author><name sortKey="Phan, Gq" uniqKey="Phan G">GQ Phan</name></author><author><name sortKey="Maker, Av" uniqKey="Maker A">AV Maker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Downey, Sg" uniqKey="Downey S">SG Downey</name></author><author><name sortKey="Klapper, Ja" uniqKey="Klapper J">JA Klapper</name></author><author><name sortKey="Smith, Fo" uniqKey="Smith F">FO Smith</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Beck, Ke" uniqKey="Beck K">KE Beck</name></author><author><name sortKey="Blansfield, Ja" uniqKey="Blansfield J">JA Blansfield</name></author><author><name sortKey="Tran, Kq" uniqKey="Tran K">KQ Tran</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hamid, O" uniqKey="Hamid O">O Hamid</name></author><author><name sortKey="Chin, K" uniqKey="Chin K">K Chin</name></author><author><name sortKey="Li, J" uniqKey="Li J">J Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="O Day, Sj" uniqKey="O Day S">SJ O'Day</name></author><author><name sortKey="Ibrahim, R" uniqKey="Ibrahim R">R Ibrahim</name></author><author><name sortKey="Depril, V" uniqKey="Depril V">V DePril</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wolchok, Jd" uniqKey="Wolchok J">JD Wolchok</name></author><author><name sortKey="Ibrahim, R" uniqKey="Ibrahim R">R Ibrahim</name></author><author><name sortKey="Depril, V" uniqKey="Depril V">V DePril</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hodi, Fs" uniqKey="Hodi F">FS Hodi</name></author><author><name sortKey="Hoos, A" uniqKey="Hoos A">A Hoos</name></author><author><name sortKey="Ibrahim, R" uniqKey="Ibrahim R">R Ibrahim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ribas, A" uniqKey="Ribas A">A Ribas</name></author><author><name sortKey="Antonia, S" uniqKey="Antonia S">S Antonia</name></author><author><name sortKey="Sosman, J" uniqKey="Sosman J">J Sosman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gomez Navarro, J" uniqKey="Gomez Navarro J">J Gomez-Navarro</name></author><author><name sortKey="Antonia, S" uniqKey="Antonia S">S Antonia</name></author><author><name sortKey="Sosman, J" uniqKey="Sosman J">J Sosman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kirkwood, Jm" uniqKey="Kirkwood J">JM Kirkwood</name></author><author><name sortKey="Lorigan, P" uniqKey="Lorigan P">P Lorigan</name></author><author><name sortKey="Hersey, P" uniqKey="Hersey P">P Hersey</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ribas, A" uniqKey="Ribas A">A Ribas</name></author><author><name sortKey="Hauschild, A" uniqKey="Hauschild A">A Hauschild</name></author><author><name sortKey="Kefford, R" uniqKey="Kefford R">R Kefford</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tarhini, Aa" uniqKey="Tarhini A">AA Tarhini</name></author><author><name sortKey="Moschos, Ss" uniqKey="Moschos S">SS Moschos</name></author><author><name sortKey="Schlesselman, Jj" uniqKey="Schlesselman J">JJ Schlesselman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, B" uniqKey="Li B">B Li</name></author><author><name sortKey="Lin, J" uniqKey="Lin J">J Lin</name></author><author><name sortKey="Vanroey, M" uniqKey="Vanroey M">M Vanroey</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Choi, Bk" uniqKey="Choi B">BK Choi</name></author><author><name sortKey="Kim, Yh" uniqKey="Kim Y">YH Kim</name></author><author><name sortKey="Kang, Wj" uniqKey="Kang W">WJ Kang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sznol, M" uniqKey="Sznol M">M Sznol</name></author><author><name sortKey="Hodi, Fs" uniqKey="Hodi F">FS Hodi</name></author><author><name sortKey="Margolin, K" uniqKey="Margolin K">K Margolin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Trikha, M" uniqKey="Trikha M">M Trikha</name></author><author><name sortKey="Zhou, Z" uniqKey="Zhou Z">Z Zhou</name></author><author><name sortKey="Nemeth, Ja" uniqKey="Nemeth J">JA Nemeth</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jayson, Gc" uniqKey="Jayson G">GC Jayson</name></author><author><name sortKey="Mullamitha, S" uniqKey="Mullamitha S">S Mullamitha</name></author><author><name sortKey="Ton, C" uniqKey="Ton C">C Ton</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cranmer, Ld" uniqKey="Cranmer L">LD Cranmer</name></author><author><name sortKey="Bedikian, Ay" uniqKey="Bedikian A">AY Bedikian</name></author><author><name sortKey="Ribas, A" uniqKey="Ribas A">A Ribas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Linette, G" uniqKey="Linette G">G Linette</name></author><author><name sortKey="Cranmer, L" uniqKey="Cranmer L">L Cranmer</name></author><author><name sortKey="Hodi, S" uniqKey="Hodi S">S Hodi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mulgrew, K" uniqKey="Mulgrew K">K Mulgrew</name></author><author><name sortKey="Kinneer, K" uniqKey="Kinneer K">K Kinneer</name></author><author><name sortKey="Yao, Xt" uniqKey="Yao X">XT Yao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hersey, P" uniqKey="Hersey P">P Hersey</name></author><author><name sortKey="Sosman, J" uniqKey="Sosman J">J Sosman</name></author><author><name sortKey="O Day, S" uniqKey="O Day S">S O'Day</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rosenberg, Sa" uniqKey="Rosenberg S">SA Rosenberg</name></author><author><name sortKey="Yang, Jc" uniqKey="Yang J">JC Yang</name></author><author><name sortKey="Restifo, Np" uniqKey="Restifo N">NP Restifo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sondak, Vk" uniqKey="Sondak V">VK Sondak</name></author><author><name sortKey="Sabel, Ms" uniqKey="Sabel M">MS Sabel</name></author><author><name sortKey="Mule, Jj" uniqKey="Mule J">JJ Mule</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Morton, Dl" uniqKey="Morton D">DL Morton</name></author><author><name sortKey="Mozzillo, N" uniqKey="Mozzillo N">N Mozzillo</name></author><author><name sortKey="Thompson, Jf" uniqKey="Thompson J">JF Thompson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Srivastava, P" uniqKey="Srivastava P">P Srivastava</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Belli, F" uniqKey="Belli F">F Belli</name></author><author><name sortKey="Testori, A" uniqKey="Testori A">A Testori</name></author><author><name sortKey="Rivoltini, L" uniqKey="Rivoltini L">L Rivoltini</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Testori, A" uniqKey="Testori A">A Testori</name></author><author><name sortKey="Richards, J" uniqKey="Richards J">J Richards</name></author><author><name sortKey="Whitman, E" uniqKey="Whitman E">E Whitman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Coulie, Pg" uniqKey="Coulie P">PG Coulie</name></author><author><name sortKey="Karanikas, V" uniqKey="Karanikas V">V Karanikas</name></author><author><name sortKey="Colau, D" uniqKey="Colau D">D Colau</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kruit, Wh" uniqKey="Kruit W">WH Kruit</name></author><author><name sortKey="Suciu, S" uniqKey="Suciu S">S Suciu</name></author><author><name sortKey="Dreno, B" uniqKey="Dreno B">B Dreno</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Purcell, Aw" uniqKey="Purcell A">AW Purcell</name></author><author><name sortKey="Mccluskey, J" uniqKey="Mccluskey J">J McCluskey</name></author><author><name sortKey="Rossjohn, J" uniqKey="Rossjohn J">J Rossjohn</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Melief, Cj" uniqKey="Melief C">CJ Melief</name></author><author><name sortKey="Van Der Burg, Sh" uniqKey="Van Der Burg S">SH van der Burg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Osada, T" uniqKey="Osada T">T Osada</name></author><author><name sortKey="Clay, Tm" uniqKey="Clay T">TM Clay</name></author><author><name sortKey="Woo, Cy" uniqKey="Woo C">CY Woo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thurner, B" uniqKey="Thurner B">B Thurner</name></author><author><name sortKey="Haendle, I" uniqKey="Haendle I">I Haendle</name></author><author><name sortKey="Roder, C" uniqKey="Roder C">C Roder</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schadendorf, D" uniqKey="Schadendorf D">D Schadendorf</name></author><author><name sortKey="Ugurel, S" uniqKey="Ugurel S">S Ugurel</name></author><author><name sortKey="Schuler Thurner, B" uniqKey="Schuler Thurner B">B Schuler-Thurner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lesterhuis, Wj" uniqKey="Lesterhuis W">WJ Lesterhuis</name></author><author><name sortKey="Aarntzen, Eh" uniqKey="Aarntzen E">EH Aarntzen</name></author><author><name sortKey="De Vries, Ij" uniqKey="De Vries I">IJ De Vries</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lens, M" uniqKey="Lens M">M Lens</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dummer, R" uniqKey="Dummer R">R Dummer</name></author><author><name sortKey="Rochlitz, C" uniqKey="Rochlitz C">C Rochlitz</name></author><author><name sortKey="Velu, T" uniqKey="Velu T">T Velu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Heinzerling, L" uniqKey="Heinzerling L">L Heinzerling</name></author><author><name sortKey="Burg, G" uniqKey="Burg G">G Burg</name></author><author><name sortKey="Dummer, R" uniqKey="Dummer R">R Dummer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mahvi, Dm" uniqKey="Mahvi D">DM Mahvi</name></author><author><name sortKey="Henry, Mb" uniqKey="Henry M">MB Henry</name></author><author><name sortKey="Albertini, Mr" uniqKey="Albertini M">MR Albertini</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Senzer, Nn" uniqKey="Senzer N">NN Senzer</name></author><author><name sortKey="Kaufman, Hl" uniqKey="Kaufman H">HL Kaufman</name></author><author><name sortKey="Amatruda, T" uniqKey="Amatruda T">T Amatruda</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gattinoni, L" uniqKey="Gattinoni L">L Gattinoni</name></author><author><name sortKey="Powell, Dj" uniqKey="Powell D">DJ Powell</name></author><author><name sortKey="Rosenberg, Sa" uniqKey="Rosenberg S">SA Rosenberg</name></author><author><name sortKey="Restifo, Np" uniqKey="Restifo N">NP Restifo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mule, Jj" uniqKey="Mule J">JJ Mule</name></author><author><name sortKey="Shu, S" uniqKey="Shu S">S Shu</name></author><author><name sortKey="Schwarz, Sl" uniqKey="Schwarz S">SL Schwarz</name></author><author><name sortKey="Rosenberg, Sa" uniqKey="Rosenberg S">SA Rosenberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rosenberg, Sa" uniqKey="Rosenberg S">SA Rosenberg</name></author><author><name sortKey="Spiess, P" uniqKey="Spiess P">P Spiess</name></author><author><name sortKey="Lafreniere, R" uniqKey="Lafreniere R">R Lafreniere</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rosenberg, Sa" uniqKey="Rosenberg S">SA Rosenberg</name></author><author><name sortKey="Yannelli, Jr" uniqKey="Yannelli J">JR Yannelli</name></author><author><name sortKey="Yang, Jc" uniqKey="Yang J">JC Yang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dudley, Me" uniqKey="Dudley M">ME Dudley</name></author><author><name sortKey="Wunderlich, Jr" uniqKey="Wunderlich J">JR Wunderlich</name></author><author><name sortKey="Robbins, Pf" uniqKey="Robbins P">PF Robbins</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mackensen, A" uniqKey="Mackensen A">A Mackensen</name></author><author><name sortKey="Meidenbauer, N" uniqKey="Meidenbauer N">N Meidenbauer</name></author><author><name sortKey="Vogl, S" uniqKey="Vogl S">S Vogl</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Powell, Dj" uniqKey="Powell D">DJ Powell</name></author><author><name sortKey="Dudley, Me" uniqKey="Dudley M">ME Dudley</name></author><author><name sortKey="Hogan, Ka" uniqKey="Hogan K">KA Hogan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hunder, Nn" uniqKey="Hunder N">NN Hunder</name></author><author><name sortKey="Wallen, H" uniqKey="Wallen H">H Wallen</name></author><author><name sortKey="Cao, J" uniqKey="Cao J">J Cao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dudley, Me" uniqKey="Dudley M">ME Dudley</name></author><author><name sortKey="Wunderlich, Jr" uniqKey="Wunderlich J">JR Wunderlich</name></author><author><name sortKey="Yang, Jc" uniqKey="Yang J">JC Yang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rosenberg, Sa" uniqKey="Rosenberg S">SA Rosenberg</name></author><author><name sortKey="Restifo, Np" uniqKey="Restifo N">NP Restifo</name></author><author><name sortKey="Yang, Jc" uniqKey="Yang J">JC Yang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Morgan, Ra" uniqKey="Morgan R">RA Morgan</name></author><author><name sortKey="Dudley, Me" uniqKey="Dudley M">ME Dudley</name></author><author><name sortKey="Wunderlich, Jr" uniqKey="Wunderlich J">JR Wunderlich</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tran, Kq" uniqKey="Tran K">KQ Tran</name></author><author><name sortKey="Zhou, J" uniqKey="Zhou J">J Zhou</name></author><author><name sortKey="Durflinger, Kh" uniqKey="Durflinger K">KH Durflinger</name></author></analytic></biblStruct></listBibl></div1></back></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd \
| NlmPubMed2Wicri -a AustralieFrV1
| This area was generated with Dilib version V0.6.33. |  |