Minimum Information Specification For In Situ Hybridization and Immunohistochemistry Experiments (MISFISHIE)
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Auteurs : Eric W. Deutsch [États-Unis] ; Catherine A. Ball [États-Unis] ; Jules J. Berman [États-Unis] ; G Steven Bova [États-Unis] ; Alvis Brazma [Royaume-Uni] ; Roger E. Bumgarner [États-Unis] ; David Campbell [États-Unis] ; Helen C. Causton [Royaume-Uni] ; Jeffrey H. Christiansen [Royaume-Uni] ; Fabrice Daian [France] ; Delphine Dauga [France] ; Duncan R. Davidson [Royaume-Uni] ; Gregory Gimenez [France] ; Young Ah Goo [États-Unis] ; Sean Grimmond [Australie] ; Thorsten Henrich [Allemagne] ; Bernhard G. Herrmann [Allemagne] ; Michael H. Johnson [États-Unis] ; Martin Korb [États-Unis] ; Jason C. Mills [États-Unis] ; Asa J. Oudes [États-Unis] ; Helen E. Parkinson [Royaume-Uni] ; Laura E. Pascal [États-Unis] ; Nicolas Pollet [France] ; John Quackenbush [États-Unis] ; Mirana Ramialison [Allemagne] ; Martin Ringwald [États-Unis] ; David Salgado [France] ; Susanna-Assunta Sansone [Royaume-Uni] ; Gavin Sherlock [États-Unis] ; Christian J. Stoeckert [États-Unis] ; Jason Swedlow [Royaume-Uni] ; Ronald C. Taylor [États-Unis] ; Laura Walashek [États-Unis] ; Anthony Warford [Royaume-Uni] ; David G. Wilkinson [Royaume-Uni] ; Yi Zhou [États-Unis] ; Leonard I. Zon [États-Unis] ; Alvin Y. Liu [États-Unis] ; Lawrence D. True [États-Unis]Source :
- Nature biotechnology [ 1087-0156 ] ; 2008.
Abstract
One purpose of the biomedical literature is to report results in sufficient detail so that the methods of data collection and analysis can be independently replicated and verified. Here we present for consideration a minimum information specification for gene expression localization experiments, called the “Minimum Information Specification For In Situ Hybridization and Immunohistochemistry Experiments (MISFISHIE)”. It is modelled after the MIAME (Minimum Information About a Microarray Experiment) specification for microarray experiments. Data specifications like MIAME and MISFISHIE specify the information
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DOI: 10.1038/nbt1391
PubMed: 18327244
PubMed Central: 4367930
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Ball</name><affiliation wicri:level="2"><nlm:aff id="A2">Department of Biochemistry, Stanford University School of Medicine, 279 Campus Drive West, Stanford, CA 94305, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biochemistry, Stanford University School of Medicine, 279 Campus Drive West, Stanford, CA 94305</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Berman, Jules J" sort="Berman, Jules J" uniqKey="Berman J" first="Jules J" last="Berman">Jules J. 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Bumgarner</name><affiliation wicri:level="4"><nlm:aff id="A6">Department of Microbiology, University of Washington, Seattle, WA 98195, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology, University of Washington, Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Campbell, David" sort="Campbell, David" uniqKey="Campbell D" first="David" last="Campbell">David Campbell</name><affiliation wicri:level="2"><nlm:aff id="A1">Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Causton, Helen C" sort="Causton, Helen C" uniqKey="Causton H" first="Helen C" last="Causton">Helen C. Causton</name><affiliation wicri:level="1"><nlm:aff id="A7">MRC CSC Microarray Centre, Imperial College School of Medicine, London, W12 ONN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC CSC Microarray Centre, Imperial College School of Medicine, London, W12 ONN</wicri:regionArea><wicri:noRegion>W12 ONN</wicri:noRegion></affiliation></author><author><name sortKey="Christiansen, Jeffrey H" sort="Christiansen, Jeffrey H" uniqKey="Christiansen J" first="Jeffrey H" last="Christiansen">Jeffrey H. 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Davidson</name><affiliation wicri:level="3"><nlm:aff id="A8">MRC Human Genetics Unit, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU</nlm:aff><country>Royaume-Uni</country><wicri:regionArea>MRC Human Genetics Unit, Western General Hospital, Crewe Road, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Gimenez, Gregory" sort="Gimenez, Gregory" uniqKey="Gimenez G" first="Gregory" last="Gimenez">Gregory Gimenez</name><affiliation wicri:level="4"><nlm:aff id="A9">Institut de Biologie du Développement de Marseille, UMR 6216, CNRS/Université de la Méditerranée, Parc Scientifique de Luminy, Case 907, F-13288 Marseille Cedex 9, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Institut de Biologie du Développement de Marseille, UMR 6216, CNRS/Université de la Méditerranée, Parc Scientifique de Luminy, Case 907, F-13288 Marseille Cedex 9</wicri:regionArea><placeName><region type="region" nuts="2">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement><settlement type="city">Marseille</settlement></placeName><orgName type="university">Université de la Méditerranée</orgName></affiliation></author><author><name sortKey="Goo, Young Ah" sort="Goo, Young Ah" uniqKey="Goo Y" first="Young Ah" last="Goo">Young Ah Goo</name><affiliation wicri:level="2"><nlm:aff id="A1">Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A10">Department of Urology, University of Washington, Seattle, WA 98195, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Urology, University of Washington, Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Grimmond, Sean" sort="Grimmond, Sean" uniqKey="Grimmond S" first="Sean" last="Grimmond">Sean Grimmond</name><affiliation wicri:level="1"><nlm:aff id="A11">Institute for Molecular Bioscience, University of Queensland, St. Lucia, Qld, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Institute for Molecular Bioscience, University of Queensland, St. Lucia, Qld</wicri:regionArea><wicri:noRegion>Qld</wicri:noRegion></affiliation></author><author><name sortKey="Henrich, Thorsten" sort="Henrich, Thorsten" uniqKey="Henrich T" first="Thorsten" last="Henrich">Thorsten Henrich</name><affiliation wicri:level="3"><nlm:aff id="A12">EMBL Heidelberg, Meyerhofstrasse 1, D-69117 Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>EMBL Heidelberg, Meyerhofstrasse 1, D-69117 Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Herrmann, Bernhard G" sort="Herrmann, Bernhard G" uniqKey="Herrmann B" first="Bernhard G" last="Herrmann">Bernhard G. Herrmann</name><affiliation wicri:level="3"><nlm:aff id="A13">Institute for medical Genetics, Charité-CBF, and Dept. Developmental Genetics, Max-Planck-Institute for molecular Genetics, Ihnestrasse 73, 14195 Berlin, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for medical Genetics, Charité-CBF, and Dept. Developmental Genetics, Max-Planck-Institute for molecular Genetics, Ihnestrasse 73, 14195 Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Johnson, Michael H" sort="Johnson, Michael H" uniqKey="Johnson M" first="Michael H" last="Johnson">Michael H. Johnson</name><affiliation wicri:level="2"><nlm:aff id="A1">Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Korb, Martin" sort="Korb, Martin" uniqKey="Korb M" first="Martin" last="Korb">Martin Korb</name><affiliation wicri:level="2"><nlm:aff id="A1">Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Mills, Jason C" sort="Mills, Jason C" uniqKey="Mills J" first="Jason C" last="Mills">Jason C. Mills</name><affiliation wicri:level="4"><nlm:aff id="A14">Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName></affiliation></author><author><name sortKey="Oudes, Asa J" sort="Oudes, Asa J" uniqKey="Oudes A" first="Asa J" last="Oudes">Asa J. Oudes</name><affiliation wicri:level="2"><nlm:aff id="A1">Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A10">Department of Urology, University of Washington, Seattle, WA 98195, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Urology, University of Washington, Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Parkinson, Helen E" sort="Parkinson, Helen E" uniqKey="Parkinson H" first="Helen E" last="Parkinson">Helen E. Parkinson</name><affiliation wicri:level="1"><nlm:aff id="A5">EMBL-EBI, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>EMBL-EBI, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD</wicri:regionArea><wicri:noRegion>Cambridge CB10 1SD</wicri:noRegion></affiliation></author><author><name sortKey="Pascal, Laura E" sort="Pascal, Laura E" uniqKey="Pascal L" first="Laura E" last="Pascal">Laura E. Pascal</name><affiliation wicri:level="2"><nlm:aff id="A1">Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A10">Department of Urology, University of Washington, Seattle, WA 98195, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Urology, University of Washington, Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Pollet, Nicolas" sort="Pollet, Nicolas" uniqKey="Pollet N" first="Nicolas" last="Pollet">Nicolas Pollet</name><affiliation wicri:level="4"><nlm:aff id="A15">CNRS UMR 8080, Université Paris-Sud, 91405 Orsay, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>CNRS UMR 8080, Université Paris-Sud, 91405 Orsay</wicri:regionArea><wicri:noRegion>91405 Orsay</wicri:noRegion><orgName type="university">Université Paris-Sud</orgName><placeName><settlement type="city">Orsay</settlement><region type="region" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Quackenbush, John" sort="Quackenbush, John" uniqKey="Quackenbush J" first="John" last="Quackenbush">John Quackenbush</name><affiliation wicri:level="2"><nlm:aff id="A16">Dana-Farber Cancer Institute, 44 Binney Street, M232, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Dana-Farber Cancer Institute, 44 Binney Street, M232, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Ramialison, Mirana" sort="Ramialison, Mirana" uniqKey="Ramialison M" first="Mirana" last="Ramialison">Mirana Ramialison</name><affiliation wicri:level="3"><nlm:aff id="A12">EMBL Heidelberg, Meyerhofstrasse 1, D-69117 Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>EMBL Heidelberg, Meyerhofstrasse 1, D-69117 Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Ringwald, Martin" sort="Ringwald, Martin" uniqKey="Ringwald M" first="Martin" last="Ringwald">Martin Ringwald</name><affiliation wicri:level="2"><nlm:aff id="A17">The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609</wicri:regionArea><placeName><region type="state">Maine (État)</region></placeName></affiliation></author><author><name sortKey="Salgado, David" sort="Salgado, David" uniqKey="Salgado D" first="David" last="Salgado">David Salgado</name><affiliation wicri:level="4"><nlm:aff id="A9">Institut de Biologie du Développement de Marseille, UMR 6216, CNRS/Université de la Méditerranée, Parc Scientifique de Luminy, Case 907, F-13288 Marseille Cedex 9, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Institut de Biologie du Développement de Marseille, UMR 6216, CNRS/Université de la Méditerranée, Parc Scientifique de Luminy, Case 907, F-13288 Marseille Cedex 9</wicri:regionArea><wicri:noRegion>13288 Marseille Cedex 9</wicri:noRegion><orgName type="university">Université de la Méditerranée</orgName><placeName><settlement type="city">Marseille</settlement><region type="region" nuts="2">Provence-Alpes-Côte d'Azur</region></placeName></affiliation></author><author><name sortKey="Sansone, Susanna Assunta" sort="Sansone, Susanna Assunta" uniqKey="Sansone S" first="Susanna-Assunta" last="Sansone">Susanna-Assunta Sansone</name><affiliation wicri:level="1"><nlm:aff id="A5">EMBL-EBI, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>EMBL-EBI, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD</wicri:regionArea><wicri:noRegion>Cambridge CB10 1SD</wicri:noRegion></affiliation></author><author><name sortKey="Sherlock, Gavin" sort="Sherlock, Gavin" uniqKey="Sherlock G" first="Gavin" last="Sherlock">Gavin Sherlock</name><affiliation wicri:level="2"><nlm:aff id="A18">Department of Genetics, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305-5120, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genetics, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305-5120</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Stoeckert, Christian J" sort="Stoeckert, Christian J" uniqKey="Stoeckert C" first="Christian J" last="Stoeckert">Christian J. Stoeckert</name><affiliation wicri:level="2"><nlm:aff id="A19">Center for Bioinformatics and Department of Genetics, University of Pennsylvania, Philadelphia, PA 19104, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Bioinformatics and Department of Genetics, University of Pennsylvania, Philadelphia, PA 19104</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Swedlow, Jason" sort="Swedlow, Jason" uniqKey="Swedlow J" first="Jason" last="Swedlow">Jason Swedlow</name><affiliation wicri:level="2"><nlm:aff id="A20">Division of Gene Regulation and Expression, Wellcome Trust Biocentre, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland</nlm:aff><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>Division of Gene Regulation and Expression, Wellcome Trust Biocentre, University of Dundee, Dow Street, Dundee DD1 5EH</wicri:cityArea></affiliation></author><author><name sortKey="Taylor, Ronald C" sort="Taylor, Ronald C" uniqKey="Taylor R" first="Ronald C" last="Taylor">Ronald C. Taylor</name><affiliation wicri:level="2"><nlm:aff id="A21">Computational Biology & Bioinformatics Group, Pacific Northwest National Laboratory, PO Box 999, MS K7-90, Richland, WA 99352, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Computational Biology & Bioinformatics Group, Pacific Northwest National Laboratory, PO Box 999, MS K7-90, Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Walashek, Laura" sort="Walashek, Laura" uniqKey="Walashek L" first="Laura" last="Walashek">Laura Walashek</name><affiliation wicri:level="2"><nlm:aff id="A1">Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A10">Department of Urology, University of Washington, Seattle, WA 98195, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Urology, University of Washington, Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Warford, Anthony" sort="Warford, Anthony" uniqKey="Warford A" first="Anthony" last="Warford">Anthony Warford</name><affiliation wicri:level="1"><nlm:aff id="A22">Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 IHH, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 IHH</wicri:regionArea><wicri:noRegion>Cambridge CB10 IHH</wicri:noRegion></affiliation></author><author><name sortKey="Wilkinson, David G" sort="Wilkinson, David G" uniqKey="Wilkinson D" first="David G" last="Wilkinson">David G. Wilkinson</name><affiliation wicri:level="1"><nlm:aff id="A23">Division of Developmental Neurobiology, National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Developmental Neurobiology, National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA</wicri:regionArea><wicri:noRegion>London NW7 1AA</wicri:noRegion></affiliation></author><author><name sortKey="Zhou, Yi" sort="Zhou, Yi" uniqKey="Zhou Y" first="Yi" last="Zhou">Yi Zhou</name><affiliation wicri:level="2"><nlm:aff id="A24">Stem Cell Program, Division of Hematology/Oncology, Children’s Hospital Boston and Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Stem Cell Program, Division of Hematology/Oncology, Children’s Hospital Boston and Harvard Medical School, 300 Longwood Ave, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Zon, Leonard I" sort="Zon, Leonard I" uniqKey="Zon L" first="Leonard I" last="Zon">Leonard I. Zon</name><affiliation wicri:level="2"><nlm:aff id="A24">Stem Cell Program, Division of Hematology/Oncology, Children’s Hospital Boston and Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Stem Cell Program, Division of Hematology/Oncology, Children’s Hospital Boston and Harvard Medical School, 300 Longwood Ave, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Liu, Alvin Y" sort="Liu, Alvin Y" uniqKey="Liu A" first="Alvin Y" last="Liu">Alvin Y. Liu</name><affiliation wicri:level="2"><nlm:aff id="A1">Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A10">Department of Urology, University of Washington, Seattle, WA 98195, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Urology, University of Washington, Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="True, Lawrence D" sort="True, Lawrence D" uniqKey="True L" first="Lawrence D" last="True">Lawrence D. True</name><affiliation wicri:level="4"><nlm:aff id="A25">Department of Pathology, University of Washington, Seattle, WA 98195-6100, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pathology, University of Washington, Seattle, WA 98195-6100</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">18327244</idno><idno type="pmc">4367930</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367930</idno><idno type="RBID">PMC:4367930</idno><idno type="doi">10.1038/nbt1391</idno><date when="2008">2008</date><idno type="wicri:Area/Pmc/Corpus">002196</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002196</idno><idno type="wicri:Area/Pmc/Curation">002047</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002047</idno><idno type="wicri:Area/Pmc/Checkpoint">002966</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">002966</idno><idno type="wicri:Area/Ncbi/Merge">000353</idno><idno type="wicri:Area/Ncbi/Curation">000353</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Minimum Information Specification For In Situ Hybridization and Immunohistochemistry Experiments (MISFISHIE)</title><author><name sortKey="Deutsch, Eric W" sort="Deutsch, Eric W" uniqKey="Deutsch E" first="Eric W" last="Deutsch">Eric W. Deutsch</name><affiliation wicri:level="2"><nlm:aff id="A1">Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Ball, Catherine A" sort="Ball, Catherine A" uniqKey="Ball C" first="Catherine A" last="Ball">Catherine A. Ball</name><affiliation wicri:level="2"><nlm:aff id="A2">Department of Biochemistry, Stanford University School of Medicine, 279 Campus Drive West, Stanford, CA 94305, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biochemistry, Stanford University School of Medicine, 279 Campus Drive West, Stanford, CA 94305</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Berman, Jules J" sort="Berman, Jules J" uniqKey="Berman J" first="Jules J" last="Berman">Jules J. Berman</name><affiliation wicri:level="2"><nlm:aff id="A3">Association for Pathology Informatics, 9650 Rockville Pike, Bethesda, MD 20814, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Association for Pathology Informatics, 9650 Rockville Pike, Bethesda, MD 20814</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Bova, G Steven" sort="Bova, G Steven" uniqKey="Bova G" first="G Steven" last="Bova">G Steven Bova</name><affiliation wicri:level="2"><nlm:aff id="A4">Johns Hopkins University School of Medicine, PELICAN Laboratory, Departments of Pathology , Health Information Sciences, Genetic Medicine, Oncology, and Urology, Baltimore, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Johns Hopkins University School of Medicine, PELICAN Laboratory, Departments of Pathology , Health Information Sciences, Genetic Medicine, Oncology, and Urology, Baltimore, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Brazma, Alvis" sort="Brazma, Alvis" uniqKey="Brazma A" first="Alvis" last="Brazma">Alvis Brazma</name><affiliation wicri:level="1"><nlm:aff id="A5">EMBL-EBI, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>EMBL-EBI, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD</wicri:regionArea><wicri:noRegion>Cambridge CB10 1SD</wicri:noRegion></affiliation></author><author><name sortKey="Bumgarner, Roger E" sort="Bumgarner, Roger E" uniqKey="Bumgarner R" first="Roger E" last="Bumgarner">Roger E. Bumgarner</name><affiliation wicri:level="4"><nlm:aff id="A6">Department of Microbiology, University of Washington, Seattle, WA 98195, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology, University of Washington, Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Campbell, David" sort="Campbell, David" uniqKey="Campbell D" first="David" last="Campbell">David Campbell</name><affiliation wicri:level="2"><nlm:aff id="A1">Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Causton, Helen C" sort="Causton, Helen C" uniqKey="Causton H" first="Helen C" last="Causton">Helen C. Causton</name><affiliation wicri:level="1"><nlm:aff id="A7">MRC CSC Microarray Centre, Imperial College School of Medicine, London, W12 ONN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC CSC Microarray Centre, Imperial College School of Medicine, London, W12 ONN</wicri:regionArea><wicri:noRegion>W12 ONN</wicri:noRegion></affiliation></author><author><name sortKey="Christiansen, Jeffrey H" sort="Christiansen, Jeffrey H" uniqKey="Christiansen J" first="Jeffrey H" last="Christiansen">Jeffrey H. Christiansen</name><affiliation wicri:level="3"><nlm:aff id="A8">MRC Human Genetics Unit, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU</nlm:aff><country>Royaume-Uni</country><wicri:regionArea>MRC Human Genetics Unit, Western General Hospital, Crewe Road, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Daian, Fabrice" sort="Daian, Fabrice" uniqKey="Daian F" first="Fabrice" last="Daian">Fabrice Daian</name><affiliation wicri:level="4"><nlm:aff id="A9">Institut de Biologie du Développement de Marseille, UMR 6216, CNRS/Université de la Méditerranée, Parc Scientifique de Luminy, Case 907, F-13288 Marseille Cedex 9, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Institut de Biologie du Développement de Marseille, UMR 6216, CNRS/Université de la Méditerranée, Parc Scientifique de Luminy, Case 907, F-13288 Marseille Cedex 9</wicri:regionArea><placeName><region type="region" nuts="2">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement><settlement type="city">Marseille</settlement></placeName><orgName type="university">Université de la Méditerranée</orgName></affiliation></author><author><name sortKey="Dauga, Delphine" sort="Dauga, Delphine" uniqKey="Dauga D" first="Delphine" last="Dauga">Delphine Dauga</name><affiliation wicri:level="4"><nlm:aff id="A9">Institut de Biologie du Développement de Marseille, UMR 6216, CNRS/Université de la Méditerranée, Parc Scientifique de Luminy, Case 907, F-13288 Marseille Cedex 9, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Institut de Biologie du Développement de Marseille, UMR 6216, CNRS/Université de la Méditerranée, Parc Scientifique de Luminy, Case 907, F-13288 Marseille Cedex 9</wicri:regionArea><wicri:noRegion>13288 Marseille Cedex 9</wicri:noRegion><orgName type="university">Université de la Méditerranée</orgName><placeName><settlement type="city">Marseille</settlement><region type="region" nuts="2">Provence-Alpes-Côte d'Azur</region></placeName></affiliation></author><author><name sortKey="Davidson, Duncan R" sort="Davidson, Duncan R" uniqKey="Davidson D" first="Duncan R" last="Davidson">Duncan R. Davidson</name><affiliation wicri:level="3"><nlm:aff id="A8">MRC Human Genetics Unit, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU</nlm:aff><country>Royaume-Uni</country><wicri:regionArea>MRC Human Genetics Unit, Western General Hospital, Crewe Road, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Gimenez, Gregory" sort="Gimenez, Gregory" uniqKey="Gimenez G" first="Gregory" last="Gimenez">Gregory Gimenez</name><affiliation wicri:level="4"><nlm:aff id="A9">Institut de Biologie du Développement de Marseille, UMR 6216, CNRS/Université de la Méditerranée, Parc Scientifique de Luminy, Case 907, F-13288 Marseille Cedex 9, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Institut de Biologie du Développement de Marseille, UMR 6216, CNRS/Université de la Méditerranée, Parc Scientifique de Luminy, Case 907, F-13288 Marseille Cedex 9</wicri:regionArea><placeName><region type="region" nuts="2">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement><settlement type="city">Marseille</settlement></placeName><orgName type="university">Université de la Méditerranée</orgName></affiliation></author><author><name sortKey="Goo, Young Ah" sort="Goo, Young Ah" uniqKey="Goo Y" first="Young Ah" last="Goo">Young Ah Goo</name><affiliation wicri:level="2"><nlm:aff id="A1">Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A10">Department of Urology, University of Washington, Seattle, WA 98195, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Urology, University of Washington, Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Grimmond, Sean" sort="Grimmond, Sean" uniqKey="Grimmond S" first="Sean" last="Grimmond">Sean Grimmond</name><affiliation wicri:level="1"><nlm:aff id="A11">Institute for Molecular Bioscience, University of Queensland, St. Lucia, Qld, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Institute for Molecular Bioscience, University of Queensland, St. Lucia, Qld</wicri:regionArea><wicri:noRegion>Qld</wicri:noRegion></affiliation></author><author><name sortKey="Henrich, Thorsten" sort="Henrich, Thorsten" uniqKey="Henrich T" first="Thorsten" last="Henrich">Thorsten Henrich</name><affiliation wicri:level="3"><nlm:aff id="A12">EMBL Heidelberg, Meyerhofstrasse 1, D-69117 Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>EMBL Heidelberg, Meyerhofstrasse 1, D-69117 Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Herrmann, Bernhard G" sort="Herrmann, Bernhard G" uniqKey="Herrmann B" first="Bernhard G" last="Herrmann">Bernhard G. Herrmann</name><affiliation wicri:level="3"><nlm:aff id="A13">Institute for medical Genetics, Charité-CBF, and Dept. Developmental Genetics, Max-Planck-Institute for molecular Genetics, Ihnestrasse 73, 14195 Berlin, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for medical Genetics, Charité-CBF, and Dept. Developmental Genetics, Max-Planck-Institute for molecular Genetics, Ihnestrasse 73, 14195 Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Johnson, Michael H" sort="Johnson, Michael H" uniqKey="Johnson M" first="Michael H" last="Johnson">Michael H. Johnson</name><affiliation wicri:level="2"><nlm:aff id="A1">Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Korb, Martin" sort="Korb, Martin" uniqKey="Korb M" first="Martin" last="Korb">Martin Korb</name><affiliation wicri:level="2"><nlm:aff id="A1">Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Mills, Jason C" sort="Mills, Jason C" uniqKey="Mills J" first="Jason C" last="Mills">Jason C. Mills</name><affiliation wicri:level="4"><nlm:aff id="A14">Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName></affiliation></author><author><name sortKey="Oudes, Asa J" sort="Oudes, Asa J" uniqKey="Oudes A" first="Asa J" last="Oudes">Asa J. Oudes</name><affiliation wicri:level="2"><nlm:aff id="A1">Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A10">Department of Urology, University of Washington, Seattle, WA 98195, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Urology, University of Washington, Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Parkinson, Helen E" sort="Parkinson, Helen E" uniqKey="Parkinson H" first="Helen E" last="Parkinson">Helen E. Parkinson</name><affiliation wicri:level="1"><nlm:aff id="A5">EMBL-EBI, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>EMBL-EBI, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD</wicri:regionArea><wicri:noRegion>Cambridge CB10 1SD</wicri:noRegion></affiliation></author><author><name sortKey="Pascal, Laura E" sort="Pascal, Laura E" uniqKey="Pascal L" first="Laura E" last="Pascal">Laura E. Pascal</name><affiliation wicri:level="2"><nlm:aff id="A1">Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A10">Department of Urology, University of Washington, Seattle, WA 98195, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Urology, University of Washington, Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Pollet, Nicolas" sort="Pollet, Nicolas" uniqKey="Pollet N" first="Nicolas" last="Pollet">Nicolas Pollet</name><affiliation wicri:level="4"><nlm:aff id="A15">CNRS UMR 8080, Université Paris-Sud, 91405 Orsay, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>CNRS UMR 8080, Université Paris-Sud, 91405 Orsay</wicri:regionArea><wicri:noRegion>91405 Orsay</wicri:noRegion><orgName type="university">Université Paris-Sud</orgName><placeName><settlement type="city">Orsay</settlement><region type="region" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Quackenbush, John" sort="Quackenbush, John" uniqKey="Quackenbush J" first="John" last="Quackenbush">John Quackenbush</name><affiliation wicri:level="2"><nlm:aff id="A16">Dana-Farber Cancer Institute, 44 Binney Street, M232, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Dana-Farber Cancer Institute, 44 Binney Street, M232, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Ramialison, Mirana" sort="Ramialison, Mirana" uniqKey="Ramialison M" first="Mirana" last="Ramialison">Mirana Ramialison</name><affiliation wicri:level="3"><nlm:aff id="A12">EMBL Heidelberg, Meyerhofstrasse 1, D-69117 Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>EMBL Heidelberg, Meyerhofstrasse 1, D-69117 Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Ringwald, Martin" sort="Ringwald, Martin" uniqKey="Ringwald M" first="Martin" last="Ringwald">Martin Ringwald</name><affiliation wicri:level="2"><nlm:aff id="A17">The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609</wicri:regionArea><placeName><region type="state">Maine (État)</region></placeName></affiliation></author><author><name sortKey="Salgado, David" sort="Salgado, David" uniqKey="Salgado D" first="David" last="Salgado">David Salgado</name><affiliation wicri:level="4"><nlm:aff id="A9">Institut de Biologie du Développement de Marseille, UMR 6216, CNRS/Université de la Méditerranée, Parc Scientifique de Luminy, Case 907, F-13288 Marseille Cedex 9, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Institut de Biologie du Développement de Marseille, UMR 6216, CNRS/Université de la Méditerranée, Parc Scientifique de Luminy, Case 907, F-13288 Marseille Cedex 9</wicri:regionArea><wicri:noRegion>13288 Marseille Cedex 9</wicri:noRegion><orgName type="university">Université de la Méditerranée</orgName><placeName><settlement type="city">Marseille</settlement><region type="region" nuts="2">Provence-Alpes-Côte d'Azur</region></placeName></affiliation></author><author><name sortKey="Sansone, Susanna Assunta" sort="Sansone, Susanna Assunta" uniqKey="Sansone S" first="Susanna-Assunta" last="Sansone">Susanna-Assunta Sansone</name><affiliation wicri:level="1"><nlm:aff id="A5">EMBL-EBI, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>EMBL-EBI, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD</wicri:regionArea><wicri:noRegion>Cambridge CB10 1SD</wicri:noRegion></affiliation></author><author><name sortKey="Sherlock, Gavin" sort="Sherlock, Gavin" uniqKey="Sherlock G" first="Gavin" last="Sherlock">Gavin Sherlock</name><affiliation wicri:level="2"><nlm:aff id="A18">Department of Genetics, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305-5120, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genetics, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305-5120</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Stoeckert, Christian J" sort="Stoeckert, Christian J" uniqKey="Stoeckert C" first="Christian J" last="Stoeckert">Christian J. Stoeckert</name><affiliation wicri:level="2"><nlm:aff id="A19">Center for Bioinformatics and Department of Genetics, University of Pennsylvania, Philadelphia, PA 19104, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Bioinformatics and Department of Genetics, University of Pennsylvania, Philadelphia, PA 19104</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Swedlow, Jason" sort="Swedlow, Jason" uniqKey="Swedlow J" first="Jason" last="Swedlow">Jason Swedlow</name><affiliation wicri:level="2"><nlm:aff id="A20">Division of Gene Regulation and Expression, Wellcome Trust Biocentre, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland</nlm:aff><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>Division of Gene Regulation and Expression, Wellcome Trust Biocentre, University of Dundee, Dow Street, Dundee DD1 5EH</wicri:cityArea></affiliation></author><author><name sortKey="Taylor, Ronald C" sort="Taylor, Ronald C" uniqKey="Taylor R" first="Ronald C" last="Taylor">Ronald C. Taylor</name><affiliation wicri:level="2"><nlm:aff id="A21">Computational Biology & Bioinformatics Group, Pacific Northwest National Laboratory, PO Box 999, MS K7-90, Richland, WA 99352, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Computational Biology & Bioinformatics Group, Pacific Northwest National Laboratory, PO Box 999, MS K7-90, Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Walashek, Laura" sort="Walashek, Laura" uniqKey="Walashek L" first="Laura" last="Walashek">Laura Walashek</name><affiliation wicri:level="2"><nlm:aff id="A1">Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A10">Department of Urology, University of Washington, Seattle, WA 98195, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Urology, University of Washington, Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Warford, Anthony" sort="Warford, Anthony" uniqKey="Warford A" first="Anthony" last="Warford">Anthony Warford</name><affiliation wicri:level="1"><nlm:aff id="A22">Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 IHH, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 IHH</wicri:regionArea><wicri:noRegion>Cambridge CB10 IHH</wicri:noRegion></affiliation></author><author><name sortKey="Wilkinson, David G" sort="Wilkinson, David G" uniqKey="Wilkinson D" first="David G" last="Wilkinson">David G. Wilkinson</name><affiliation wicri:level="1"><nlm:aff id="A23">Division of Developmental Neurobiology, National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Developmental Neurobiology, National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA</wicri:regionArea><wicri:noRegion>London NW7 1AA</wicri:noRegion></affiliation></author><author><name sortKey="Zhou, Yi" sort="Zhou, Yi" uniqKey="Zhou Y" first="Yi" last="Zhou">Yi Zhou</name><affiliation wicri:level="2"><nlm:aff id="A24">Stem Cell Program, Division of Hematology/Oncology, Children’s Hospital Boston and Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Stem Cell Program, Division of Hematology/Oncology, Children’s Hospital Boston and Harvard Medical School, 300 Longwood Ave, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Zon, Leonard I" sort="Zon, Leonard I" uniqKey="Zon L" first="Leonard I" last="Zon">Leonard I. Zon</name><affiliation wicri:level="2"><nlm:aff id="A24">Stem Cell Program, Division of Hematology/Oncology, Children’s Hospital Boston and Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Stem Cell Program, Division of Hematology/Oncology, Children’s Hospital Boston and Harvard Medical School, 300 Longwood Ave, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Liu, Alvin Y" sort="Liu, Alvin Y" uniqKey="Liu A" first="Alvin Y" last="Liu">Alvin Y. Liu</name><affiliation wicri:level="2"><nlm:aff id="A1">Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A10">Department of Urology, University of Washington, Seattle, WA 98195, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Urology, University of Washington, Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="True, Lawrence D" sort="True, Lawrence D" uniqKey="True L" first="Lawrence D" last="True">Lawrence D. True</name><affiliation wicri:level="4"><nlm:aff id="A25">Department of Pathology, University of Washington, Seattle, WA 98195-6100, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pathology, University of Washington, Seattle, WA 98195-6100</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author></analytic><series><title level="j">Nature biotechnology</title><idno type="ISSN">1087-0156</idno><idno type="eISSN">1546-1696</idno><imprint><date when="2008">2008</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">One purpose of the biomedical literature is to report results in sufficient detail so that the methods of data collection and analysis can be independently replicated and verified. Here we present for consideration a minimum information specification for gene expression localization experiments, called the “Minimum Information Specification For In Situ Hybridization and Immunohistochemistry Experiments (MISFISHIE)”. It is modelled after the MIAME (Minimum Information About a Microarray Experiment) specification for microarray experiments. Data specifications like MIAME and MISFISHIE specify the information <italic>content</italic> without dictating a <italic>format</italic> for encoding that information. The MISFISHIE specification describes six types of information that should be provided for each experiment: Experimental Design, Biomaterials and Treatments, Reporters, Staining, Imaging Data, and Image Characterizations. This specification has benefited the consortium within which it was initially developed and is expected to benefit the wider research community. We welcome feedback from the scientific community to help improve our proposal.</p></div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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